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The Current Evidence for Vegetarian and Vegan Diets in the Management of Type 2 Diabetes 素食和纯素饮食治疗 2 型糖尿病的现有证据
IF 8 1区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2024-10-01 DOI: 10.1016/j.advnut.2024.100296
Sabrina Schlesinger , Lukas Schwingshackl
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引用次数: 0
Emerging Evidence and Critical Issues with the Use of Single-Drop Capillary Blood for the Measurement of Hemoglobin Concentration in Population-Level Anemia Surveys 透视:在人群贫血调查中使用单滴毛细管血液测量血红蛋白浓度的新证据和关键问题。
IF 8 1区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2024-10-01 DOI: 10.1016/j.advnut.2024.100290
Crystal D Karakochuk , Omar Dary , Monica C Flores-Urrutia , Maria Nieves Garcia-Casal , Chika Hayashi , Maria Elena D Jefferds , Robert Johnston , Leila M Larson , Carine Mapango , Dora I Mazariegos Cordero , Denish Moorthy , Sorrel Namaste , Lisa M Rogers , Kuntal Saha , Sara Wuehler
Accurate and precise measurement of hemoglobin concentration is critical for reliable estimations of anemia prevalence at the population level. When systematic and/or random error are introduced in hemoglobin measurement, estimates of anemia prevalence might be significantly erroneous and, hence, limit their usefulness. For decades, single-drop capillary blood has been the most common blood source used for the measurement of hemoglobin concentration in surveys, especially in low-income and middle-income countries. In this study, we highlight historical and emerging evidence that single-drop capillary blood introduces a high degree of random error (variability) to hemoglobin estimates, leading to less reliable estimates of anemia prevalence at the population level. At present, the best practice is to collect and use venous blood for measurement of hemoglobin with an automated hematology analyzer, following standard operating procedures and quality assurance measures. Where use of an automated analyzer is not possible, the analysis of venous blood in a point-of-care hemoglobinometer by trained phlebotomists or specimen collectors should be considered. A forthcoming systematic review will provide additional evidence on the accuracy and precision of single-drop capillary blood for hemoglobin assessment. In the meantime, we raise caution when using single-drop capillary blood for hemoglobin measurement as it can result in inaccurate hemoglobin estimates and less reliable anemia prevalence estimates.
准确、精确地测量血红蛋白浓度对于可靠地估算人群贫血患病率至关重要。如果在血红蛋白测量中引入了系统误差和/或随机误差,贫血患病率的估算值就可能出现严重错误,从而限制了其实用性。几十年来,单滴毛细管血一直是调查中测量血红蛋白浓度最常用的血源,尤其是在中低收入国家。在此,我们强调了历史和新出现的证据,即单滴毛细管血液会给血红蛋白估计值带来很大的随机误差(变异性),从而导致对人群贫血患病率的估计不够可靠。目前,最佳做法是按照标准操作程序和质量保证措施,使用自动血液分析仪采集和使用静脉血测量血红蛋白。如果无法使用自动分析仪,则应考虑由训练有素的抽血员或标本采集员使用护理点血红蛋白仪分析静脉血。即将进行的系统综述将为单滴毛细管血进行血红蛋白评估的准确性和精确性提供更多证据。与此同时,我们建议在使用单滴毛细管血液测量血红蛋白时要谨慎,因为这会导致血红蛋白估计值不准确,贫血患病率估计值也不可靠。
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引用次数: 0
The Use of Ginger Bioactive Compounds in Pregnancy: An Evidence Scan and Umbrella Review of Existing Meta-Analyses 妊娠期使用生姜生物活性化合物:证据扫描和现有荟萃分析综述。
IF 8 1区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2024-09-28 DOI: 10.1016/j.advnut.2024.100308
Kendra A Tiani , Cristina M Arenaz , Maureen K Spill , Margaret J Foster , Julie S Davis , Regan L Bailey , Martha S Field , Patrick J Stover , Amanda J MacFarlane
Ginger is a commonly used nonpharmacological treatment of pregnancy-related symptoms including nausea and vomiting, inflammation, and gastrointestinal dysfunction. Determining the efficacy of ginger is particularly important during pregnancy and lactation when maternal and neonatal detrimental effects may be a concern. This evidence scan and umbrella review aimed to assess the extent and quality of the evidence regarding the effectiveness and safety of using dietary preparations of ginger during pregnancy and lactation. We searched MEDLINE, Embase, CAB Abstracts, and International Pharmaceutical Abstracts up to 20 December, 2023, to identify maternal and neonatal outcomes associated with ginger use during pregnancy or lactation compared to placebo or conventional medicines. Outcomes for which a meta-analysis (MA) of intervention studies was identified were synthesized in an umbrella review. The AMSTAR-2 (A MeaSurement Tool to Assess systematic Reviews-2) tool was used to critically appraise the reviews. The percent overlap in primary studies was calculated overall and pairwise for each included MA. Data extracted from each MA included the summary estimate of the effect of ginger, the formulation of the ginger treatment, gestational timepoint at intervention, population enrolled in the study, type of intervention, comparator intervention, and number of study participants. The evidence scan identified 90 articles relevant to ginger use during pregnancy and lactation. Seven MAs of ginger use for treating nausea and vomiting of pregnancy reported 22 independent studies with a 49% study overlap overall. The majority of the MAs found a significant positive effect of ginger on the improvement of nausea in pregnancy compared with placebo, or equivalence to conventional treatments, and no evidence of significant adverse effects. The quality of the MAs ranged from critically low to low. The evidence suggests that ginger is effective at reducing nausea in pregnancy; however, the included studies contained substantial heterogeneity and were of low quality.
背景:生姜是一种常用的非药物治疗方法,可用于治疗与妊娠有关的症状,包括恶心和呕吐、炎症和胃肠功能紊乱。在妊娠期和哺乳期,确定生姜的疗效尤为重要,因为此时可能会对母体和新生儿产生不利影响:这项证据扫描和总体回顾旨在评估有关孕期和哺乳期使用生姜膳食制剂的有效性和安全性的证据的范围和质量:方法:我们检索了截至 2023 年 12 月 20 日的 MEDLINE、Embase、CAB Abstracts 和 International Pharmaceutical Abstracts,以确定与安慰剂或常规药物相比,孕期或哺乳期使用生姜的相关孕产妇和新生儿结果。对干预研究的荟萃分析(MA)结果进行了汇总。采用 AMSTAR-2 工具对综述进行严格评估。对每项纳入的荟萃分析计算主要研究的总体重叠率和配对重叠率。从每篇MA中提取的数据包括生姜效果的简要估计值、生姜治疗的配方、干预时的妊娠时间点、参与研究的人群、干预类型、对比干预以及研究参与者的数量:证据扫描发现了 90 篇与孕期和哺乳期使用生姜相关的文章。关于生姜用于治疗妊娠恶心和呕吐的 7 项 MA 报告了 22 项独立研究,研究重叠率为 49%。与安慰剂相比,大多数生姜对改善妊娠恶心有显著的积极作用,或与常规治疗效果相当,没有证据表明生姜有明显的不良反应。这些评估报告的质量从极低到较低不等:结论:证据表明,生姜能有效减轻妊娠期恶心症状;然而,纳入的研究存在很大的异质性,且质量较低:尽管孕妇普遍使用生姜制剂,但最近关于生姜使用的综述并未关注这一弱势群体食用生姜的潜在健康结果。
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引用次数: 0
The Role of Iron in Intestinal Mucus: Perspectives from Both the Host and Gut Microbiota 肠粘液中铁的作用:来自宿主和肠道微生物群的视角。
IF 8 1区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2024-09-26 DOI: 10.1016/j.advnut.2024.100307
Shuan Liu , Jie Yin , Dan Wan , Yulong Yin
Although research on the role of iron in host immunity has a history spanning decades, it is only relatively recently that attention has been directed toward the biological effects of iron on the intestinal mucus layer, prompted by an evolving understanding of the role of this material in immune defense. The mucus layer, secreted by intestinal goblet cells, covers the intestinal epithelium, and given its unique location, interactions between the host and gut microbiota, as well as among constituent microbiota, occur frequently within the mucus layer. Iron, as an essential nutrient for the vast majority of life forms, regulates immune responses from both the host and microbial perspectives. In this review, we summarize the iron metabolism of both the host and gut microbiota and describe how iron contributes to intestinal mucosal homeostasis via the intestinal mucus layer with respect to both host and constituent gut microbiota. The findings described herein offer a new perspective on iron-mediated intestinal mucosal barrier function.
尽管有关铁在宿主免疫中作用的研究已有几十年的历史,但直到最近,人们才开始关注铁对肠粘液层的生物效应,这是因为人们对这种物质在免疫防御中作用的认识在不断发展。粘液层由肠道鹅口疮细胞分泌,覆盖在肠道上皮细胞上,由于其独特的位置,宿主与肠道微生物群之间以及组成微生物群之间的相互作用经常发生在粘液层内。铁是绝大多数生命形式的必需营养素,从宿主和微生物的角度调节免疫反应。在这篇综述中,我们总结了宿主和肠道微生物群的铁代谢,并描述了铁如何通过肠道粘液层对宿主和组成肠道微生物群的肠道粘膜平衡做出贡献。本文所述的研究结果为了解铁介导的肠粘膜屏障功能提供了一个新的视角。
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引用次数: 0
A Narrative Review of Strategies to Optimize Nutrition, Feeding, and Growth among Preterm-Born Infants: Implications for Practice 早产儿营养、喂养和生长优化策略综述》:对实践的启示。
IF 8 1区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2024-09-21 DOI: 10.1016/j.advnut.2024.100305
Faith E Bala , Katlyn E McGrattan , Christina J Valentine , Sudarshan R Jadcherla
Preterm birth is the leading cause of neonatal and under-5 mortality globally, and healthcare-related burden and nutrition-related morbidities are unsustainable, particularly in resource-limited regions. Additionally, preterm infants are susceptible to multiple adverse outcomes including growth faltering, suboptimal neurodevelopment, and multisystemic morbidities. Maturation, healing, repair, and restoration to normalcy in preterm-born infants require optimizing nutrition; only then, prognosis, growth, neurodevelopment, and overall quality of life can improve. In this article, we discuss the various evidence-based feeding and nutritional strategies that can be applicable even in resource-limited settings, where resources and infrastructure for advanced neonatal care are limited. This article addresses nutrition, feeding strategies, and growth monitoring in the neonatal intensive care unit and at discharge to optimize nutrition, growth, and development.
早产是全球新生儿和五岁以下儿童死亡的主要原因,与医疗相关的负担和与营养相关的发病率是不可持续的,尤其是在资源有限的地区。此外,早产儿容易出现多种不良后果,包括生长发育迟缓、神经发育不达标和多系统疾病。早产儿的成熟、愈合、修复和恢复正常需要优化营养;只有这样,才能改善预后、生长、神经发育和整体生活质量。在本文中,我们讨论了各种循证喂养和营养策略,这些策略即使在资源有限的环境中也能适用,因为在这些环境中,先进的新生儿护理资源和基础设施都很有限。本文探讨了新生儿重症监护室(NICU)和出院时的营养、喂养策略和生长监测,以优化营养、生长和发育。意义说明:早产儿的营养和生长评估以及营养优化是全球面临的一个重要问题。我们回顾了近期的相关文献,为包括营养师、护士、喂养治疗师和医生在内的跨学科团队提供了最新信息。
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引用次数: 0
Carotenoids 类胡萝卜素‡。
IF 8 1区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2024-09-18 DOI: 10.1016/j.advnut.2024.100304
Abdulkerim Eroglu , Genan Wang , Nathan Crook , Torsten Bohn
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引用次数: 0
Addressing Infant and Young Child Feeding Recommendations From a Planetary Health Perspective 从地球健康的角度提出婴幼儿喂养建议。
IF 8 1区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2024-09-13 DOI: 10.1016/j.advnut.2024.100303
Andrea Santos-Guzmán , Juan A Rivera , Mishel Unar-Munguía , Ivonne Ramírez-Silva
Current international infant and young child (IYC) feeding recommendations consider nutrition and health but not environmental impacts. Only a handful of countries have dietary guidelines that provide quantitative recommendations for food groups of environmental concern. This study aimed to perform a narrative review of the environmental impacts of commercial milk formula compared with breastfeeding and to analyze the degree to which current country-specific IYC feeding recommendations are aligned with sustainable dietary targets. A mixed-methods review was conducted, including the following: 1) a narrative review of the environmental impact of commercial milk formula compared with breastfeeding and 2) a comparison of recommended intake of meats and dairy for children IYC based on country-specific dietary guidelines compared with the EAT–Lancet Commission dietary targets (ELCT) for children 24 mo or older and adults and if the ELCT should be adjusted for the energy needs of IYC. Formula feeding has a greater environmental impact (∼48% higher carbon footprint) than exclusive breastfeeding. Available country-specific dietary guidelines for meat and dairy products in children IYC are, in general, at or below the upper limits of the ELCT recommended ranges for older children and adults but are in most cases above the upper limit when adjusting for the energy needs of IYC. Exclusive breastfeeding should be protected and promoted not only as the healthier but also as the most sustainable alternative. Available complementary dietary feeding recommendations of nonprocessed meat and dairy fall below current ELCT for older children and adults. Given that IYC require a more nutrient-dense diet than older children and adults and considering the small quantities they consume, we recommend using the unadjusted ELCT as reference for IYC feeding while specific international consumption recommendations are developed for this age group.
当前国际婴幼儿(IYC)喂养建议考虑了营养和健康,但没有考虑环境影响。只有少数几个国家的膳食指南对环境问题食品类别提出了量化建议:对商业配方奶粉与母乳喂养对环境的影响进行叙述性综述,并分析目前各国的国际幼儿保育喂养建议在多大程度上与可持续膳食目标保持一致:方法:采用混合方法进行回顾,包括:a) 对商业配方奶粉与母乳喂养对环境的影响进行叙述性回顾;b) 比较根据各国膳食指南推荐的国际幼儿中心儿童肉类和乳制品摄入量与针对 24 个月或以上儿童和成人的 "吃-胰委员会 "膳食目标(ELCT),以及是否应根据国际幼儿中心的能量需求对 "吃-胰委员会 "膳食目标进行调整:结果:与纯母乳喂养相比,配方奶喂养对环境的影响更大(碳足迹高出 48%)。各国现有的针对国际幼儿中心儿童的肉类和乳制品膳食指南一般处于或低于 ELCT 推荐的较大儿童和成人膳食范围的上限,但在根据国际幼儿中心的能量需求进行调整后,大多数情况下高于上限:结论:纯母乳喂养不仅是更健康的选择,也是最可持续的选择,因此应得到保护和推广。现有的非加工肉类和乳制品补充膳食喂养建议低于目前针对年长儿童和成人的 ELCT。鉴于幼儿和儿童需要比年龄较大的儿童和成人摄入营养密度更高的膳食,同时考虑到他们的摄入量较小,我们建议在国际上为这一年龄组制定具体的消费建议时,使用未经调整的 ELCT 作为幼儿和儿童喂养的参考。
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引用次数: 0
The Carbon Isotope Ratio as an Objective Biomarker of Added Sugar Intake: A Scoping Review of Current Evidence in Human Nutrition 碳稳定同位素比(CIR)作为添加糖摄入量的客观生物标志物:人类营养学现有证据范围综述》。
IF 8 1区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2024-09-01 DOI: 10.1016/j.advnut.2024.100281
Gina L Tripicchio , Alissa D Smethers , Jessica J Johnson , Jordan A Olenginski , Diane M O’Brien , Jennifer Orlet Fisher , Vitalina A Robinson , Sarah H Nash

Objective biomarkers of dietary intake are needed to advance nutrition research. The carbon isotope ratio (C13/C12; CIR) holds promise as an objective biomarker of added sugar (AS) and sugar-sweetened beverage (SSB) intake. This systematic scoping review presents the current evidence on CIRs from human studies. Search results (through April 12, 2024) yielded 6297 studies and 24 final articles. Studies were observational (n = 12), controlled feeding (n = 10), or dietary interventions (n = 2). CIRs were sampled from blood (n = 23), hair (n = 5), breath (n = 2), and/or adipose tissue (n = 1). Most (n = 17) conducted whole tissue (that is, bulk) analysis, 8 used compound specific isotope analysis (CSIA), and/or 2 studies used methods appropriate for analyzing breath. Studies were conducted in 3 concentrated geographic regions of the United States (n = 7 Virginia; n = 5 Arizona; n = 4 Alaska), with only 2 studies conducted in other countries. Studies that used CSIA to examine the CIR from the amino acid alanine (CIR-Ala; n = 4) and CIR analyzed from breath (n = 2) provided the most robust evidence for CIR as an objective biomarker of AS and SSBs (R2 range 0.36–0.91). Studies using bulk analysis of hair or blood showed positive, but modest and more variable associations with AS and SSBs (R2 range 0.05–0.48). Few studies showed no association, particularly in non-United States populations and those with low AS and SSB intakes. Two studies provided evidence for CIR to detect changes in SSB intake in response to dietary interventions. Overall, the most compelling evidence supports CIR-Ala as an objective indicator of AS intake and breath CIR as an indicator of short-term AS intake. Considering how to adjust for underlying dietary patterns remains an important area of future work and emerging methods using breath and CSIA warrant additional investigation. More evidence is needed to refine the utility and specificity of CIRs to measure AS and SSB intake.

推进营养研究需要客观的膳食摄入生物标志物。碳稳定同位素比值(C13/C12;CIR)有望成为添加糖(AS)和含糖饮料(SSB)摄入量的客观生物标志物。本系统性范围综述介绍了目前人类研究中有关 CIR 的证据。搜索结果(截至 2024 年 4 月 12 日)共获得 6297 项研究和 24 篇最终文章。研究为观察性研究(12 篇)、控制喂养研究(10 篇)或膳食干预研究(2 篇)。CIR 取样于血液(23 例)、毛发(5 例)、呼气(2 例)和/或脂肪组织(1 例)。大多数研究(n=17)进行了整体组织(即块状)分析,8 项研究使用了特定化合物同位素分析 (CSIA),和/或 2 项研究使用了适合分析呼气的方法。研究集中在美国的三个地理区域进行(弗吉尼亚州 7 项;亚利桑那州 5 项;阿拉斯加州 4 项),只有两项研究在其他国家进行。使用 CSIA 检测来自非必需氨基酸丙氨酸的 CIR(CIR-Ala;n=4)和来自呼气分析的 CIR(n=2)的研究提供了最有力的证据,证明 CIR 是 AS 和 SSB 的客观生物标志物(R2 范围为 0.36-0.91)。对毛发或血液进行批量分析的研究表明,CIR 与 AS 和 SSB 呈正相关,但相关性不大,且差异较大(R2 范围为 0.05-0.48)。少数研究显示两者之间没有关联,尤其是在非美国人口和 AS 与 SSB 摄入量较低的人群中。有两项研究证明,CIR 可检测膳食干预对 SSB 摄入量的影响。总之,最有说服力的证据支持将 CIR-Ala 作为 AS 摄入量的客观指标,并将呼气 CIR 作为短期 AS 摄入量的指标。考虑如何调整潜在的膳食模式仍然是未来工作的一个重要领域,使用呼气和 CSIA 的新方法值得进一步研究。还需要更多的证据来完善CIRs在测量AS和SSB摄入量方面的实用性和特异性。
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引用次数: 0
Artificial Intelligence in Malnutrition: A Systematic Literature Review 营养不良中的人工智能:系统文献综述。
IF 8 1区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2024-09-01 DOI: 10.1016/j.advnut.2024.100264

Malnutrition among the population of the world is a frequent yet underdiagnosed problem in both children and adults. Development of malnutrition screening and diagnostic tools for early detection of malnutrition is necessary to prevent long-term complications to patients’ health and well-being. Most of these tools are based on predefined questionnaires and consensus guidelines. The use of artificial intelligence (AI) allows for automated tools to detect malnutrition in an earlier stage to prevent long-term consequences. In this study, a systematic literature review was carried out with the goal of providing detailed information on what patient groups, screening tools, machine learning algorithms, data types, and variables are being used, as well as the current limitations and implementation stage of these AI-based tools. The results showed that a staggering majority exceeding 90% of all AI models go unused in day-to-day clinical practice. Furthermore, supervised learning models seemed to be the most popular type of learning. Alongside this, disease-related malnutrition was the most common category of malnutrition found in the analysis of all primary studies. This research provides a resource for researchers to identify directions for their research on the use of AI in malnutrition.

营养不良是世界人口中经常出现的问题,但对儿童和成人的诊断都不足。有必要开发营养不良筛查和诊断工具,以便及早发现营养不良,防止对患者健康和福祉造成长期并发症。这些工具大多基于预定义问卷和共识指南。人工智能(AI)的使用可使自动工具更早地检测出营养不良,从而预防长期后果。在这项研究中,我们进行了系统的文献综述,目的是提供详细信息,说明正在使用哪些患者群体、筛查工具、机器学习算法、数据类型和变量,以及这些人工智能工具目前的局限性和实施阶段。结果显示,在日常临床实践中,超过 90% 的人工智能模型未被使用,比例之高令人吃惊。此外,监督学习模型似乎是最受欢迎的学习类型。与此同时,与疾病相关的营养不良是所有主要研究分析中发现的最常见的营养不良类别。目前的研究为研究人员提供了一个资源库,帮助他们确定在营养不良中使用人工智能的研究方向。
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引用次数: 0
The Effect of Whole-Diet Interventions on Memory and Cognitive Function in Healthy Older Adults – A Systematic Review 全膳食干预对健康老年人记忆力和认知功能的影响--系统综述。
IF 8 1区 医学 Q1 NUTRITION & DIETETICS Pub Date : 2024-09-01 DOI: 10.1016/j.advnut.2024.100291
Lina Tingö , Cecilia Bergh , Julia Rode , Maria Fernanda Roca Rubio , Jonas Persson , Linnea Brengesjö Johnson , Lotte H Smit , Ashley N Hutchinson

An increasing number of cross-sectional studies suggests that diet may impact memory and cognition in healthy older adults. However, randomized controlled trials investigating the effects of whole-diet interventions on memory and cognition in healthy older adults are rather rare, and conflicting results are often reported. Therefore, a systematic review was conducted to compile the current evidence regarding the potential effects of whole-diet interventions on 1) memory and 2) other cognitive outcomes in older adults. Studies that reported on randomized controlled trials with dietary interventions in healthy older adults (≥60 y) were included. Studies utilizing supplements, single food items, or trials in specific patient groups (i.e., neurodegenerative diagnoses) were excluded. For the 23 included articles, the main outcomes examined fell into 1 or more of the following categories: cognitive task-based outcomes related to memory, other cognitive task-based outcomes, and additional outcomes related to cognitive function or disease risk. Three of the studies that investigated dietary interventions alone and 2 multidomain studies showed positive effects on memory function, whereas 5 multidomain interventions and 1 intervention that focused on diet alone showed positive effects on other cognitive outcomes. The effect of randomized, controlled whole-diet interventions on memory and cognitive function in healthy older adults is modest and inconclusive, highlighting the need for more well-designed, sufficiently powered studies. Furthermore, the potential mechanisms by which diet impacts cognition in healthy aging need to be elucidated.

This systematic review is registered in PROSPERO as CRD42022329759.

背景:越来越多的横断面研究表明,饮食可能会影响健康老年人的记忆力和认知能力。然而,调查全膳食干预对健康老年人记忆和认知影响的随机对照试验却相当罕见,而且报告的结果往往相互矛盾:因此,我们进行了一项系统性综述,以汇编有关全膳食干预对 1) 老年人记忆力和 2) 其他认知结果的潜在影响的现有证据:方法:纳入对健康老年人(60 岁及以上)进行饮食干预的随机对照试验的研究报告。不包括使用补充剂、单一食品或对特定患者群体(即神经退行性疾病诊断)进行试验的研究:在纳入的 23 篇文章中,主要研究结果分为以下一个或多个类别:与记忆有关的认知任务结果、其他认知任务结果以及与认知功能或疾病风险有关的其他结果。其中三项单独调查饮食干预的研究和两项多领域研究显示了对记忆功能的积极影响,而五项多领域干预和一项单独关注饮食的干预则显示了对其他认知结果的积极影响:结论:随机对照的全膳食干预对健康老年人的记忆和认知功能的影响不大,尚无定论,这突出表明需要进行更多设计合理、有充分证据支持的研究。此外,饮食影响健康老年人认知能力的潜在机制也有待阐明。系统综述或荟萃分析的注册表和注册号:本系统综述已在 PROSPERO 注册,注册号为 CRD42022329759。
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引用次数: 0
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Advances in Nutrition
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