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Modelling the probability of presence of Aedes aegypti and Aedes albopictus in Iran until 2070 2070年之前伊朗埃及伊蚊和白纹伊蚊存在的概率建模
IF 3.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-01-01 DOI: 10.4103/1995-7645.368017
M. Sedaghat, F. Omid, M. Karimi, Sajjad Haghi, A. Hanafi-Bojd
Objective: To determine the suitable ecological habitats of Aedes (Ae.) aegypti and Ae. albopictus in Iran due to climate change by the 2070s. Methods: All data relating to the spatial distribution of Ae. aegypti and Ae. albopictus worldwide, which indicated the geographical coordinates of the collection sites of these mosquitoes, were extracted from online scientific websites and entered into an Excel file. The effect of climatic and environmental variables on these mosquitoes was evaluated using the MaxEnt model in the current and future climatic conditions in the 2030s, 2050s, and 2070s. Results: The most suitable areas for the establishment of Ae. aegypti are located in the southern and northern coastal areas of Iran, based on the model outputs. The modelling result for suitable ecological niches of Ae. albopictus shows that in the current climatic conditions, the southern half of Iran from east to west, and parts of the northern coasts are prone to the presence of this species. In the future, some regions, such as Gilan and Golestan provinces, will have more potential to exist/establish Ae. albopictus. Also, according to the different climate change scenarios, suitable habitats for this species will gradually change to the northwest and west of the country. The temperature of the wettest season of the year (Bio8) and average annual temperature (Bio1) were the most effective factors in predicting the model for Ae. aegypti and Ae. albopictus, respectively. Conclusions: It is required to focus on entomological studies using different collection methods in the vulnerable areas of Iran. The future modelling results can also be used for long-term planning to prevent the entry and establishment of these invasive Aedes vectors in the country.
目的:确定埃及伊蚊和白纹伊蚊的适宜生态生境。到20世纪70年代,伊朗的白纹伊蚊将因气候变化而减少。方法:所有与伊蚊空间分布有关的资料。埃及伊蚊和伊蚊。从网上科学网站提取白纹伊蚊全球采集点地理坐标,并录入Excel文件。利用MaxEnt模型在2030年代、2050年代和2070年代的当前和未来气候条件下,评估了气候和环境变量对这些蚊子的影响。结果:该地区最适宜建立Ae。根据模型输出,埃及伊蚊位于伊朗南部和北部沿海地区。拟合的生态位模拟结果。白纹伊蚊表明,在目前的气候条件下,伊朗南半部从东到西,以及北部海岸的部分地区容易出现该物种。未来,一些地区,如吉兰省和戈列斯坦省,将更有可能存在/建立ai。蚊。此外,根据不同的气候变化情景,该物种的适宜栖息地将逐渐向西北和西部转移。全年最湿季节温度(Bio8)和年平均温度(Bio1)是预测该模型最有效的因子。埃及伊蚊和伊蚊。分别排。结论:在伊朗易感地区,应重点开展不同采集方法的昆虫学研究。未来的建模结果也可用于长期规划,以防止这些入侵伊蚊媒介在该国的进入和建立。
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引用次数: 1
Knowledge and associated factors of healthcare workers on measles vaccine and cold chain management at health institutions in Gondar, Ethiopia 埃塞俄比亚贡达尔卫生机构卫生保健工作者对麻疹疫苗和冷链管理的知识及其相关因素
IF 3.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-01-01 DOI: 10.4103/1995-7645.368019
A. Gelaw, Yeshambel Belyhun, Yitayih Wondimeneh, Mehretie Kokeb, Mulat Dagnew, Azanaw Amare, Mesert Mulu, M. Alemayehu, B. Gelaw
Objective: To assess the knowledge of healthcare workers on the measles vaccine and its cold chain management. Method: An institutional-based cross-sectional study was conducted from February 1 to March 30, 2022 in Gondar City Administration public health institutions among 165 healthcare workers. Data were collected using a structured questionnaire. In addition, an on-spot observation checklist was used to assess the availability, status and management of the cold chain. A logistic regression model was used to assess the relationship between the outcome and predictor variables. Crude and adjusted odds ratios were calculated with 95% confidence intervals. Results: Overall, 87 (52.7%; 95% Cl 44.8%-60.5%) of the healthcare workers had unsatisfactory knowledge regarding the measles vaccine and its cold chain management. One hundred thirty-six (82.4%) healthcare workers correctly mentioned the recommended range of temperature (2-8 °C) for measles vaccine storage. Healthcare workers aged 18-29 years (P=0.001) and 30-44 years (P=0.014) were observed as determinants of unsatisfactory knowledge on the measles vaccine and its cold chain management. One hundred and five (63.6%) of the healthcare workers did not correctly mention the type of measles vaccine used in routine immunization. More than one-third (36.4%) of the healthcare workers perceived that the measles vaccine is not safe and could cause measles. Conclusions: More than half of the healthcare workers in the study area had unsatisfactory knowledge on the measles vaccine and its cold chain management. It is necessary to provide technical support and in-service training for healthcare workers to ensure optimal immunization effectiveness.
目的:评估医护人员对麻疹疫苗及其冷链管理的认识。方法:2022年2月1日至3月30日,在贡达尔市公共卫生机构对165名医护人员进行了一项基于机构的横断面研究。使用结构化问卷收集数据。此外,还使用了现场观察清单来评估冷链的可用性、状态和管理。使用逻辑回归模型来评估结果与预测变量之间的关系。以95%的置信区间计算粗比值比和调整后的比值比。结果:总体而言,87名(52.7%;95%Cl 44.8%-60.5%)医护人员对麻疹疫苗及其冷链管理的了解不令人满意。136名(82.4%)医护人员正确地提到了麻疹疫苗储存的推荐温度范围(2-8°C)。18-29岁(P=0.001)和30-44岁(P=0.014)的医护人员被视为麻疹疫苗及其冷链管理知识不令人满意的决定因素。105名(63.6%)医护人员没有正确提及常规免疫中使用的麻疹疫苗类型。超过三分之一(36.4%)的医护人员认为麻疹疫苗不安全,可能导致麻疹。结论:研究地区超过一半的医护人员对麻疹疫苗及其冷链管理的了解不令人满意。有必要为医护人员提供技术支持和在职培训,以确保最佳免疫效果。
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引用次数: 1
Atypical pompholyx presentation of secondary Staphyloccoccus and Klebsiella infections in a patient with premorbid Ebstein anomaly: A case report 继发性葡萄球菌和克雷伯氏菌感染的非典型脓包表现在发病前Ebstein异常患者:1例报告
IF 3.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-01-01 DOI: 10.4103/1995-7645.368020
Hartantyo Kusuma, Dwiyanti Puspitasari, D. Husada, Leny Kartina, P. Basuki, Ismoedijanto
Rationale: Pompholyx refers to pruritic vesicles or bullous rash that mainly distribute on the palms and lateral surfaces of the fingers. It is less common among Asians, and in a severe condition, secondary bacterial infection of pompholyx can happen and result in pain, swelling and pustules. Patient concerns: A 15-year-old girl complained of progressive wound and small bumps containing yellowish pus and crusts on her hands and feet for over 6 months and worsened in the last month before admission. She also had Ebstein anomaly. Diagnosis: Atypical pompholyx with secondary Staphylococcus and Klebsiella infections. Interventions: Wound care with wet dressing and applying moisturizer on crusts, application of antibiotics for Gram positive and negative bacteria and giving nutritional support with reckoning of proper calories. Outcomes: Skin lesions were completely healed and the patient was discharged after 10 days of hospitalization. Lessons: Atypical manifestation of pompholyx makes it hard to diagnose. The diagnosis can be confirmed with meticulous history-taking and physical examination. Wound caring and controlling of the infection should be done to earn an optimal outcome.
理由:丘疹是指主要分布在手掌和手指侧面的瘙痒性小泡或大疱性皮疹。它在亚洲人中不太常见,在严重的情况下,可能会发生绒球的继发性细菌感染,并导致疼痛、肿胀和脓疱。患者担忧:一名15岁女孩抱怨她的手和脚上有6个多月的渐进性伤口和含有黄色脓液和硬皮的小肿块,并在入院前的最后一个月恶化。她也有Ebstein异常。诊断:非典型绒球炎伴继发性葡萄球菌和克雷伯氏菌感染。干预措施:用湿敷料护理伤口,在结壳上涂抹保湿霜,对革兰氏阳性菌和阴性菌使用抗生素,并在计算适当热量的情况下提供营养支持。结果:皮肤损伤完全愈合,患者在住院10天后出院。经验教训:绒球炎的非典型表现使其难以诊断。诊断可以通过仔细的病史和身体检查来确认。伤口护理和控制感染应该得到一个最佳的结果。
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引用次数: 0
Erratum: A curious hypothetical mechanism whereby malaria infection protects against COVID-19 勘误表:疟疾感染预防新冠肺炎的一种奇怪的假设机制
IF 3.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-01-01 DOI: 10.4103/1995-7645.368516
Anonymous
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引用次数: 0
Sociodemographic and clinical characteristics of SARS-CoV-2 infected population during the second and third epidemiological waves in Sri Lanka 斯里兰卡第二波和第三波疫情期间严重急性呼吸系统综合征冠状病毒2型感染人群的社会形态和临床特征
IF 3.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-01-01 DOI: 10.4103/1995-7645.368015
H. Harshani, Ruvini Wijewickrama, Gayan Wimalarathne, C. Jayamaha, J. Abeynayake
Objective: To analyze data on socio-demographic and clinical characteristics of SARS-CoV-2 infected population whose samples were received from Medical Research Institute, Sri Lanka. Methods: Laboratory based retrospective study was done on patient samples which were tested positive for SARS-CoV-2 by National Reference Virology Laboratory at the Medical Research Institute, Sri Lanka, from November, 2020 to November, 2021. Data on socio-demographic characteristics and clinical presentation of 13 126 patients were examined. Results: The mean age of the study population was (36.0±7.2) years and the majority were men (64.0%). The highest number of positive cases were found in the 21-30 years-of-age group. Two distinct peaks were noted in the incidence of SARS-CoV-2 positive individuals. In addition, 42.5% of the positive samples tested positive (42.5%) were from Medical Officer of Health collection centres. Furthermore, 60.6% (7 951) of the infected subjects were asymptomatic whereas the remaining were symptomatic. The highest percentage of symptomatic patients were observed in the 91-100 years-of-age group while the highest asymptomatic subjects were found in the 31-40 years-of-age group. The percentage of asymptomatic children (65.3%) was significantly (P<0.05) higher than that of adults (43.4%). Conclusions: The findings of this study aid decision makers to focus on the vulnerable groups, and geographic and temporal distribution of patients in the public health strategies that aim at preventing the spread of the disease and reducinig its mortalities.
目的:分析斯里兰卡医学研究所提供的严重急性呼吸系统综合征冠状病毒2型感染人群的社会人口学和临床特征数据。方法:对斯里兰卡医学研究所国家参考病毒学实验室于2020年11月至2021年11月检测出严重急性呼吸系统综合征冠状病毒2型阳性的患者样本进行实验室回顾性研究。研究了13126名患者的社会人口学特征和临床表现数据。结果:研究人群的平均年龄为(36.0±7.2)岁,大多数为男性(64.0%)。21-30岁年龄组的阳性病例最多。严重急性呼吸系统综合征冠状病毒2型阳性个体的发病率出现了两个明显的峰值。此外,42.5%的检测呈阳性的阳性样本(42.5%)来自卫生部采集中心的医务人员。此外,60.6%(7951)的受试者无症状,而其余受试者有症状。91-100岁年龄组有症状的患者比例最高,而31-40岁年龄组无症状患者比例最高。无症状儿童的比例(65.3%)显著高于成人(43.4%)(P<0.05)。结论:本研究的结果有助于决策者在旨在防止疾病传播和降低死亡率的公共卫生策略中关注弱势群体以及患者的地理和时间分布。
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引用次数: 0
Efficacy and safety of ivermectin in patients with mild and moderate COVID-19: A randomized controlled trial 伊维菌素治疗轻中度新冠肺炎患者的有效性和安全性:一项随机对照试验
IF 3.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-01-01 DOI: 10.4103/1995-7645.364007
M. Ersi, Alireza Malektojari, Sara Ghazizadeh, Elham Brahimi, Soheil Hassanipour, M. Fathalipour, Mehdi Hassaniazad
Objective: To evaluate the effectiveness and safety of ivermectin in patients with mild and moderate COVID-19. Methods: This study was a single-center, randomized, open-label, controlled trial with a 2-arm parallel-group design on 68 patients with COVID-19. According to the 1:1 ratio between the study groups (ivermectin group and standard treatment group), patients were randomly admitted to each intervention arm. Results: The mean age of the participants in the ivermectin group was (48.37±13.32) years. Eighteen of them were males (54.5%) and the participants in the control group had a mean age of (46.28±14.47) years, with nineteen of them being males (59.4%). As a primary outcome, after 5 days of randomization, there was no significant difference between the ivermectin group and the control group in the length of stay in the hospital (P=0.168). ICU admission (P=0.764), length of stay in ICU (P=0.622), in-hospital mortality (P=0.427), adverse drug reactions, and changes in the mean difference of laboratory data had not any significant difference between the two groups (except for urea change). In addition, the radiologic findings of the two groups of patients were not significantly different. Linear regression analysis showed that for every 10 years increase of age, 0.6 day of hospitalization duration was increased. There was no statistically significant association between other variables and clinical outcomes. Conclusions: Among adult hospitalized patients with moderate to severe COVID-19, there was no significant relationship between the administration of ivermectin single dose in a five-day course and clinical improvement, and mortality of the participants.
目的:评价伊维菌素治疗轻中度新冠肺炎患者的有效性和安全性。方法:本研究是一项单中心、随机、开放标签、对照试验,采用2臂平行组设计,对68例新冠肺炎患者进行研究。根据研究组(伊维菌素组和标准治疗组)之间的1:1比例,将患者随机纳入每个干预组。结果:伊维菌素组受试者的平均年龄为(48.37±13.32)岁。其中18人为男性(54.5%),对照组参与者的平均年龄为(46.28±14.47)岁,其中19人为男性(59.4%)。作为主要结果,经过5天的随机分组,伊维菌素组和对照组在住院时间上没有显著差异(P=0.168),ICU住院时间(P=0.622)、住院死亡率(P=0.427)、药物不良反应和实验室数据平均差异的变化在两组之间没有任何显著差异(尿素变化除外)。此外,两组患者的放射学检查结果没有显著差异。线性回归分析表明,年龄每增加10年,住院时间增加0.6天。其他变量与临床结果之间没有统计学意义的相关性。结论:在成年中重度新冠肺炎住院患者中,为期五天的单剂伊维菌素给药与患者的临床改善和死亡率之间没有显著关系。
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引用次数: 0
Clinical profile of tuberculosis patients in a rural teaching hospital in South-South Nigeria: a ten-year retrospective review 尼日利亚南南农村教学医院结核病患者临床概况:十年回顾性审查
IF 3.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-01-01 DOI: 10.4103/1995-7645.374356
Airenakho Emorinken
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引用次数: 0
Acknowledgment to Reviewers, 2022 对审稿人的感谢,2022
4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-01-01 DOI: 10.4103/1995-7645.370676
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引用次数: 0
Prevalence and risk factors associated with tuberculosis mortality in Brunei Darussalam 文莱达鲁萨兰国结核病发病率及与死亡率相关的危险因素
IF 3.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-01-01 DOI: 10.4103/1995-7645.368018
Liling Chaw, Nurul Jeludin, Kyaw Thu
Objective: To determine the prevalence and risk factors associated with tuberculosis mortality in Brunei Darussalam and to explore its underlying causes. Methods: A retrospective cohort study was conducted where data on socio-demographics, clinical characteristics and treatment outcomes of all tuberculosis patients registered at the National tuberculosis Coordinating Centre between 2013 and 2017 were collected. Overall tuberculosis mortality and the proportion of tuberculosis-related deaths were calculated. Logistic regression analysis was used to determine the risk factors of tuberculosis mortality when compared to those who are cured and/or completed tuberculosis treatment. Results: Of 1 107 tuberculosis cases, 99 died, giving an overall tuberculosis mortality rate of 8.9% (95% CI 7.4%-10.8%). Significant risk factors associated with tuberculosis mortality were age ⩾40 years (adjusted OR for 40-59 years was 3.89; 95% CI 1.13-1.69; adjusted OR for ⩾60 years was 22.3; 95% CI 7.27-91.9, using 20-39 years as reference), female sex (adjusted OR 1.74; 95% CI 1.09-2.79), having renal disease (adjusted OR 25.7; 95% CI 2.82-191.50) and having any cancers (adjusted OR 3.61; 95% CI 1.26-10.00). The majority (75.8%) of the recorded deaths were not related to tuberculosis. Conclusions: Tuberculosis patients who were older than 40 years, female, and having renal disease and any cancer will need close monitoring in their management program to prevent tuberculosis mortality. Clinicians should also focus on other non-tuberculosis aspects of the patient’s medical history.
目的:确定文莱达鲁萨兰国肺结核的患病率和与死亡率相关的危险因素,并探讨其根本原因。方法:进行回顾性队列研究,收集2013年至2017年间在国家结核病协调中心登记的所有结核病患者的社会人口统计、临床特征和治疗结果数据。计算了总体结核病死亡率和与结核病相关的死亡比例。与治愈和/或完成结核病治疗的患者相比,采用Logistic回归分析来确定结核病死亡率的危险因素。结果:在1107例结核病病例中,99例死亡,总体结核病死亡率为8.9%(95%CI 7.4%-10.8%)。与结核病死亡率相关的显著危险因素为年龄40岁(40-59岁的校正OR为3.89;95%CI 1.13-1.69;60岁的校正OR为22.3;95%CI 7.27-91.9,以20-39岁为参考),女性(校正OR 1.74;95%CI 1.09-2.79)、患有肾脏疾病(校正OR 25.7;95%CI 2.82-191.50)和患有任何癌症(校正OR 3.61;95%CI 1.26-10.00)。大多数(75.8%)记录的死亡与肺结核无关。结论:40岁以上、女性、患有肾病和任何癌症的结核病患者需要在其管理计划中密切监测,以预防结核病死亡。临床医生还应关注患者病史的其他非结核病方面。
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引用次数: 0
Time to stimulate Plasmodium vivax research in India: A way forward 是时候刺激印度间日疟原虫研究了:前进的道路
IF 3.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2023-01-01 DOI: 10.4103/1995-7645.368016
Himanshu Gupta, S. Nema, Praveen Bharti
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引用次数: 0
期刊
Asian Pacific journal of tropical medicine
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