Pub Date : 2023-04-18DOI: 10.3329/bsmmuj.v16i1.65668
Md Shakhawat Islam, Md. Ruhul Amin, A. Z. Hossain, Md. Tosaddeque Hossain Siddiqui, K. Islam, S. Mondal, M. Nooruzzaman, Md. Abu Bakar Akan, Farah Nazlee
Background: Pelvi-ureteric junction obstruction is the most common cause of pediatric hydronephrosis where A-H pyeloplasty with D-J stent is the established treatment option with a high success rate. We observed the predictive value of sonological parameters for early detection of postoperative obstruction at the new pelvi-ureteric junction in children following unilateral A-H pyeloplasty. Methods: This cross-sectional study included 12 children who underwent unilateral A-H pyeloplasty. Post-operative follow-up was done after D-J stent removal and completed within six months. Maximum antero-posterior pelvic diameter (APPD), cortical thickness (CT), and pelvi-cortical (P/C) ratio were compared. Results: Mean APPD was 32.7 mm at the day after removal of the stent, 24.4 mm at one month, and 19.7 mm at four months. Mean CT was 5.2 mm at the day after removal of the stent, 6.1 mm at one month and 8.0 mm at four months. P/C ratio was 8.3 mm at the day after removal of the stent, 5.2 mm at one month, and 3.4 mm at four months. Increased CT and reduced P/C ratio were significant at four months (P= 0.05). Conclusion: CT value and P/C ratio can be used as an early marker of success for pelvi-ureteric drainage following A-H pyeloplasty. Bangabandhu Sheikh Mujib Medical University Journal 2023;16(1): 58-61
背景:肾盂输尿管连接处梗阻是儿童肾积水最常见的原因，其中a - h肾盂成形术加D-J支架是目前成功率较高的治疗选择。我们观察了超声参数对儿童单侧A-H肾盂成形术术后新肾盂输尿管连接处梗阻的早期检测的预测价值。方法:本横断面研究包括12例接受单侧A-H型肾盂成形术的儿童。D-J支架取出后随访6个月。比较最大前后骨盆直径(APPD)、皮质厚度(CT)和骨盆皮质(P/C)比。结果:取出支架后1天的平均APPD为32.7 mm, 1个月时为24.4 mm, 4个月时为19.7 mm。取出支架后一天的CT平均值为5.2 mm, 1个月时为6.1 mm, 4个月时为8.0 mm。P/C比值在取出支架后一天为8.3 mm, 1个月时为5.2 mm, 4个月时为3.4 mm。4个月时CT升高，P/C降低(P= 0.05)。结论:CT值及P/C比值可作为A-H型肾盂成形术后输尿管引流成功的早期指标。Bangabandhu Sheikh Mujib医科大学学报，2023;16(1):58-61
{"title":"Post-operative sonological evaluation of pelvi-ureteric drainage of unilateral A-H pyeloplasty in children","authors":"Md Shakhawat Islam, Md. Ruhul Amin, A. Z. Hossain, Md. Tosaddeque Hossain Siddiqui, K. Islam, S. Mondal, M. Nooruzzaman, Md. Abu Bakar Akan, Farah Nazlee","doi":"10.3329/bsmmuj.v16i1.65668","DOIUrl":"https://doi.org/10.3329/bsmmuj.v16i1.65668","url":null,"abstract":"Background: Pelvi-ureteric junction obstruction is the most common cause of pediatric hydronephrosis where A-H pyeloplasty with D-J stent is the established treatment option with a high success rate. We observed the predictive value of sonological parameters for early detection of postoperative obstruction at the new pelvi-ureteric junction in children following unilateral A-H pyeloplasty.\u0000Methods: This cross-sectional study included 12 children who underwent unilateral A-H pyeloplasty. Post-operative follow-up was done after D-J stent removal and completed within six months. Maximum antero-posterior pelvic diameter (APPD), cortical thickness (CT), and pelvi-cortical (P/C) ratio were compared.\u0000Results: Mean APPD was 32.7 mm at the day after removal of the stent, 24.4 mm at one month, and 19.7 mm at four months. Mean CT was 5.2 mm at the day after removal of the stent, 6.1 mm at one month and 8.0 mm at four months. P/C ratio was 8.3 mm at the day after removal of the stent, 5.2 mm at one month, and 3.4 mm at four months. Increased CT and reduced P/C ratio were significant at four months (P= 0.05).\u0000Conclusion: CT value and P/C ratio can be used as an early marker of success for pelvi-ureteric drainage following A-H pyeloplasty.\u0000Bangabandhu Sheikh Mujib Medical University Journal 2023;16(1): 58-61\u0000 ","PeriodicalId":8681,"journal":{"name":"Bangabandhu Sheikh Mujib Medical University Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48807601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-18DOI: 10.3329/bsmmuj.v16i1.65660
Asifur Rahman, Md. Atikur Rahman, Md. Shamsul Alam, Abu Saleh Mohammad Abu Obaida, Mohammad Farid Raihan, A. N. W. Uddin, A. Hossain, Mohammad Ruhul Kuddus, M. Hossain, A. Khan
Background: The surgical management of symptomatic adult Chiari malformation type 1 (CM1) with or without syringomyelia (SM) continues to be a dilemma considering the outcomes. Objectives: The study aimed to compare the clinical outcomes between stealth cranioplasty (SC) and one of the most commonly practiced standard procedures, posterior fossa decompression with duraplasty (PFDD). Clinical outcomes between SC and another procedure posterior fossa decompression (PFD) were also compared. Methods: This comparative cross-sectional study was carried out on 37 males and 16 females symptomatic adult CM1 patients, ranging from 18 to 47 years of age from June 2019 to May 2021. Clinical outcomes were assessed, compared, and analyzed in terms of changes in clinical symptoms and signs, chicago chiari outcome scale (CCOS) score, and occurrence of complications. Results: Of the 53 patients, 23, 19 and 11 underwent SC, PFDD, and PFD, respectively. There were no significant post-operative changes in symptoms and signs among groups except changes in limb weakness between SC and PFDD (P=0.004). Considering average CCOS score, SC performed better only than PFDD (P=0.003), while category-wise SC was better than both PFDD (P=0.004) and PFD (P=0.010). Considering complications, the PFDD group had a significantly higher rate of complications than the SC group (P=0.001), while there was no significant difference in the rate of complications between the PFD and SC groups. Conclusion: SC was found to have better clinical outcomes than the PFDD and PFD groups as a technique. Bangabandhu Sheikh Mujib Medical University Journal 2023;16(1): 08-16
{"title":"Stealth cranioplasty in symptomatic adult chiari 1 malformations: Experience at Bangabandhu Sheikh Mujib Medical University","authors":"Asifur Rahman, Md. Atikur Rahman, Md. Shamsul Alam, Abu Saleh Mohammad Abu Obaida, Mohammad Farid Raihan, A. N. W. Uddin, A. Hossain, Mohammad Ruhul Kuddus, M. Hossain, A. Khan","doi":"10.3329/bsmmuj.v16i1.65660","DOIUrl":"https://doi.org/10.3329/bsmmuj.v16i1.65660","url":null,"abstract":"Background: The surgical management of symptomatic adult Chiari malformation type 1 (CM1) with or without syringomyelia (SM) continues to be a dilemma considering the outcomes.\u0000Objectives: The study aimed to compare the clinical outcomes between stealth cranioplasty (SC) and one of the most commonly practiced standard procedures, posterior fossa decompression with duraplasty (PFDD). Clinical outcomes between SC and another procedure posterior fossa decompression (PFD) were also compared.\u0000Methods: This comparative cross-sectional study was carried out on 37 males and 16 females symptomatic adult CM1 patients, ranging from 18 to 47 years of age from June 2019 to May 2021. Clinical outcomes were assessed, compared, and analyzed in terms of changes in clinical symptoms and signs, chicago chiari outcome scale (CCOS) score, and occurrence of complications. \u0000Results: Of the 53 patients, 23, 19 and 11 underwent SC, PFDD, and PFD, respectively. There were no significant post-operative changes in symptoms and signs among groups except changes in limb weakness between SC and PFDD (P=0.004). Considering average CCOS score, SC performed better only than PFDD (P=0.003), while category-wise SC was better than both PFDD (P=0.004) and PFD (P=0.010). Considering complications, the PFDD group had a significantly higher rate of complications than the SC group (P=0.001), while there was no significant difference in the rate of complications between the PFD and SC groups.\u0000Conclusion: SC was found to have better clinical outcomes than the PFDD and PFD groups as a technique.\u0000Bangabandhu Sheikh Mujib Medical University Journal 2023;16(1): 08-16","PeriodicalId":8681,"journal":{"name":"Bangabandhu Sheikh Mujib Medical University Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47542992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-18DOI: 10.3329/bsmmuj.v16i1.65662
Sonia Afroz, F. Alam, R. Saleheen, Md. Yasir Arafat, Rupash Paul, Aysha Khatun, Khandaker Md Tasnim Sajid, Abu Naser Ibne Sattar, Md. Ruhul Amin Miah
Background: This study was carried out to evaluate the utility of multiplex real-time polymerase chain reaction (PCR) to identify the common bacterial agents of community acquired pneumonia (CAP). Methods: Sputum and blood samples were collected from 80 clinically suspected CAP patients in three tertiary-level hospitals in Dhaka city. Multiplex real-time PCR assay was carried out to simultaneously detect five common bacterial agents of CAP; Streptococcus pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, Chlamydophila pneumoniae, and Legionella pneumophila. Routine microbiological methods and serology were carried out. The results of PCR were compared with culture, Gram stain and serology. Results: Among the 80 patients, sputum samples of 35 (43.7%) patients were positive by PCR, of which the most commonly detected bacteria were S. pneumoniae (25/35, 71.4%), followed by H. influenzae (9/35, 25.7%) and L. pneumophila (1/35, 2.9%). All 80 sputum samples were negative for both M. pneumoniae and C. pneumoniae by PCR. Out of the 26 culture positive sputum samples, 8 (30.7%) were positive for S. pneumoniae and 1 (3.8%) was positive for H. influenzae. Among the 52 Gram stain valid sputum samples, 24 (46.1%) were S. pneumoniae and 7 (13.5%) were H. influenzae. By serology, out of the 80 cases, M. pneumoniae was detected in 32 (40%) and C. pneumoniae in 24 (30%) of cases. Mixed infections comprised of 38.8% (31/80) cases. Conclusion: Multiplex real-time PCR is useful for the rapid and simultaneous detection of bacterial pathogens of CAP in sputum and can help support traditional laboratory methods for the accurate diagnosis of CAP patients. Bangabandhu Sheikh Mujib Medical University Journal 2023;16(1): 17-25
{"title":"Utility of multiplex real-time polymerase chain reaction for the detection of bacteria from sputum samples of community acquired pneumonia patients: A study from Dhaka, Bangladesh","authors":"Sonia Afroz, F. Alam, R. Saleheen, Md. Yasir Arafat, Rupash Paul, Aysha Khatun, Khandaker Md Tasnim Sajid, Abu Naser Ibne Sattar, Md. Ruhul Amin Miah","doi":"10.3329/bsmmuj.v16i1.65662","DOIUrl":"https://doi.org/10.3329/bsmmuj.v16i1.65662","url":null,"abstract":"Background: This study was carried out to evaluate the utility of multiplex real-time polymerase chain reaction (PCR) to identify the common bacterial agents of community acquired pneumonia (CAP).\u0000Methods: Sputum and blood samples were collected from 80 clinically suspected CAP patients in three tertiary-level hospitals in Dhaka city. Multiplex real-time PCR assay was carried out to simultaneously detect five common bacterial agents of CAP; Streptococcus pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, Chlamydophila pneumoniae, and Legionella pneumophila. Routine microbiological methods and serology were carried out. The results of PCR were compared with culture, Gram stain and serology.\u0000Results: Among the 80 patients, sputum samples of 35 (43.7%) patients were positive by PCR, of which the most commonly detected bacteria were S. pneumoniae (25/35, 71.4%), followed by H. influenzae (9/35, 25.7%) and L. pneumophila (1/35, 2.9%). All 80 sputum samples were negative for both M. pneumoniae and C. pneumoniae by PCR. Out of the 26 culture positive sputum samples, 8 (30.7%) were positive for S. pneumoniae and 1 (3.8%) was positive for H. influenzae. Among the 52 Gram stain valid sputum samples, 24 (46.1%) were S. pneumoniae and 7 (13.5%) were H. influenzae. By serology, out of the 80 cases, M. pneumoniae was detected in 32 (40%) and C. pneumoniae in 24 (30%) of cases. Mixed infections comprised of 38.8% (31/80) cases.\u0000Conclusion: Multiplex real-time PCR is useful for the rapid and simultaneous detection of bacterial pathogens of CAP in sputum and can help support traditional laboratory methods for the accurate diagnosis of CAP patients.\u0000Bangabandhu Sheikh Mujib Medical University Journal 2023;16(1): 17-25\u0000 ","PeriodicalId":8681,"journal":{"name":"Bangabandhu Sheikh Mujib Medical University Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45816288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-18DOI: 10.3329/bsmmuj.v16i1.65664
S. Afroz, A. Kabir, B. P. Dey, M. M. Rahman, Papiya Rahman, Rezwana Karim, Syeeda Shiraj Um Mahmuda, Umama-Tun-Nesa Emita, S. Jahan
Background: Primary and secondary myelofibrosis has become a global burden due to its increased mortality and morbidity. Angiogenesis is a significant driving force in the development of fibrogenesis in the bone marrow, which leads to myelofibrosis. The microvascular density (MVD) with immunomarker CD34 can be used to assess the degree of angiogenesis. The objective of this study was to examine the association between degree of myelofibrosis and angiogenesis in hematological malignancies. Methods: Forty-six trephine biopsy specimens of various hematological malignancies with myelofibrosis were studied at the Department of Pathology of Bangabandhu Sheikh Mujib Medical University. Extent of myelofibrosis in each case was assessed by examining the reticulin and Masson’s trichrome stained sections using a semiquantitative grading system of bone marrow fibrosis (MF) within a scale of MF-0 to MF-3. Angiogenesis was measured by counting MVD in the ‘hotspots’ after immunostaining with CD34 antibody. Results: The trephine biopsy cases were grouped into early fibrotic (MF-1) and advanced fibrotic (MF-2,3) consisting of 16 (34.8%) and 30 (65.2%) patients, respectively. Angiogenesis was estimated as mean MVD count which revealed 16.7 ± 5.4 and 32.0 ± 11.5 in these groups, respectively. Significant difference of mean MVD values (P<0.001) between the early and advanced fibrotic groups revealed the association of angiogenesis and degree of myelofibrosis. Conclusion: MVD may be used to measure angiogenesis in myelofibrotic marrow along with other clinical and laboratory indices as a marker of disease activity in hematological malignancies, thus aiding disease prognosis. Bangabandhu Sheikh Mujib Medical University Journal 2023;16(1): 26-34
{"title":"Degree of fibrosis and its association with angiogenesis in the myelofibrotic bone marrow","authors":"S. Afroz, A. Kabir, B. P. Dey, M. M. Rahman, Papiya Rahman, Rezwana Karim, Syeeda Shiraj Um Mahmuda, Umama-Tun-Nesa Emita, S. Jahan","doi":"10.3329/bsmmuj.v16i1.65664","DOIUrl":"https://doi.org/10.3329/bsmmuj.v16i1.65664","url":null,"abstract":"Background: Primary and secondary myelofibrosis has become a global burden due to its increased mortality and morbidity. Angiogenesis is a significant driving force in the development of fibrogenesis in the bone marrow, which leads to myelofibrosis. The microvascular density (MVD) with immunomarker CD34 can be used to assess the degree of angiogenesis. The objective of this study was to examine the association between degree of myelofibrosis and angiogenesis in hematological malignancies.\u0000Methods: Forty-six trephine biopsy specimens of various hematological malignancies with myelofibrosis were studied at the Department of Pathology of Bangabandhu Sheikh Mujib Medical University. Extent of myelofibrosis in each case was assessed by examining the reticulin and Masson’s trichrome stained sections using a semiquantitative grading system of bone marrow fibrosis (MF) within a scale of MF-0 to MF-3. Angiogenesis was measured by counting MVD in the ‘hotspots’ after immunostaining with CD34 antibody.\u0000Results: The trephine biopsy cases were grouped into early fibrotic (MF-1) and advanced fibrotic (MF-2,3) consisting of 16 (34.8%) and 30 (65.2%) patients, respectively. Angiogenesis was estimated as mean MVD count which revealed 16.7 ± 5.4 and 32.0 ± 11.5 in these groups, respectively. Significant difference of mean MVD values (P<0.001) between the early and advanced fibrotic groups revealed the association of angiogenesis and degree of myelofibrosis.\u0000Conclusion: MVD may be used to measure angiogenesis in myelofibrotic marrow along with other clinical and laboratory indices as a marker of disease activity in hematological malignancies, thus aiding disease prognosis.\u0000Bangabandhu Sheikh Mujib Medical University Journal 2023;16(1): 26-34\u0000 ","PeriodicalId":8681,"journal":{"name":"Bangabandhu Sheikh Mujib Medical University Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48637958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-18DOI: 10.3329/bsmmuj.v16i1.65671
Mazharul Hoque Bhuiyan, Md Sharfuddin Ahmed, Rajashree Das, M. S. Rahman, Md Showkat Kabir, M. Hoque
We report a rare case of perforated corneal ulcer due to recurrent viral keratitis with stromal necrosis and iris prolapse. The patient was 75 years old farmer, normotensive, diabetic, and presented with complaints of pain, watering, photophobia, redness and dimness of vision in the left eye. The left eye's visual acuity was perception of light and projection of rays in all four quadrants. Slit lamp examination found swollen eyelids, matted eyelashes, congested conjunctiva, seidel test positive, an inferonasal corneal perforation, shallow anterior chamber, irregular pupil, and prolapse of the iris through the perforated cornea. The patient was diagnosed with a left-sided perforated corneal ulcer (recurrent viral keratitis with stromal necrotizing variety) having iris prolapse. The perforation was sealed by cyanoacrylate glue and a soft bandage contact lens. This improved the patient’s condition. Early medical and surgical interventions thus can save vision as well as the eyeball. Bangabandhu Sheikh Mujib Medical University Journal 2023;16(1): 66-69
{"title":"Management of perforated corneal ulcer with iris prolapse by cyanoacrylate glue: A case report","authors":"Mazharul Hoque Bhuiyan, Md Sharfuddin Ahmed, Rajashree Das, M. S. Rahman, Md Showkat Kabir, M. Hoque","doi":"10.3329/bsmmuj.v16i1.65671","DOIUrl":"https://doi.org/10.3329/bsmmuj.v16i1.65671","url":null,"abstract":"We report a rare case of perforated corneal ulcer due to recurrent viral keratitis with stromal necrosis and iris prolapse. The patient was 75 years old farmer, normotensive, diabetic, and presented with complaints of pain, watering, photophobia, redness and dimness of vision in the left eye. The left eye's visual acuity was perception of light and projection of rays in all four quadrants. Slit lamp examination found swollen eyelids, matted eyelashes, congested conjunctiva, seidel test positive, an inferonasal corneal perforation, shallow anterior chamber, irregular pupil, and prolapse of the iris through the perforated cornea. The patient was diagnosed with a left-sided perforated corneal ulcer (recurrent viral keratitis with stromal necrotizing variety) having iris prolapse. The perforation was sealed by cyanoacrylate glue and a soft bandage contact lens. This improved the patient’s condition. Early medical and surgical interventions thus can save vision as well as the eyeball.\u0000Bangabandhu Sheikh Mujib Medical University Journal 2023;16(1): 66-69\u0000 ","PeriodicalId":8681,"journal":{"name":"Bangabandhu Sheikh Mujib Medical University Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47979007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-05DOI: 10.3329/bsmmuj.v15i4.63892
S. Mashreky, A. Rahman, M. Moniruzzaman, M. M. Zaman
Globally more than a billion people are living with disabilities. Injuries are one of the major causes of disabilities. A cross-sectional survey was conducted in 2009 to explore the epidemiology of injury-related disability in a district of Bangladesh. A total of 37,039 populations were interviewed in 8905 households both in the urban and rural area. Overall prevalence of injury-related disability was found 6.8 per 1000 population. Significantly higher rate was observed in the rural area compared to urban. Compare to female the rate was found significantly higher among male (8.5; 95% confidence interval: 7.3-9.9), compared to female (5.0; 95% CI: 4.1-6.2). Rates were found to increase with age, the highest prevalence was found among 60 years and above age group where the rate was 24.3 (95% CI: 19.0-30.6) per 1000 population. Compare to literate people illiterate people were found more vulnerable (odds ratio 3.1; 95% CI 1.7-5.9). The prevalence among illiterate was 13.4 (95% CI: 11.1-16.1) per 1000 population, and it was 3.8 (95% CI: 2.0-6.5) among higher secondary & above education level population. Falls caused more than 32% disabilities. Road traffic injuries, cuts, machine injuries, burns, and violence were the other common causes of injury disability. About 30% of the people identified with an injury-related disability mentioned that they don’t use public transports, and 65% of them mentioned this is because of their disability. About 37% people reported that they had lost their job because of the disability. Injury share the significant cause of disability in Bangladesh. Fall, road traffic injury and cuts are the common causes of injury-related disabilities. Bangabandhu Sheikh Mujib Medical University Journal 2022;15(4):16-21
{"title":"Epidemiology of injury related disabilities in a selected district in Bangladesh: A cross-sectional study","authors":"S. Mashreky, A. Rahman, M. Moniruzzaman, M. M. Zaman","doi":"10.3329/bsmmuj.v15i4.63892","DOIUrl":"https://doi.org/10.3329/bsmmuj.v15i4.63892","url":null,"abstract":"Globally more than a billion people are living with disabilities. Injuries are one of the major causes of disabilities. A cross-sectional survey was conducted in 2009 to explore the epidemiology of injury-related disability in a district of Bangladesh. A total of 37,039 populations were interviewed in 8905 households both in the urban and rural area. Overall prevalence of injury-related disability was found 6.8 per 1000 population. Significantly higher rate was observed in the rural area compared to urban. Compare to female the rate was found significantly higher among male (8.5; 95% confidence interval: 7.3-9.9), compared to female (5.0; 95% CI: 4.1-6.2). Rates were found to increase with age, the highest prevalence was found among 60 years and above age group where the rate was 24.3 (95% CI: 19.0-30.6) per 1000 population. Compare to literate people illiterate people were found more vulnerable (odds ratio 3.1; 95% CI 1.7-5.9). The prevalence among illiterate was 13.4 (95% CI: 11.1-16.1) per 1000 population, and it was 3.8 (95% CI: 2.0-6.5) among higher secondary & above education level population. Falls caused more than 32% disabilities. Road traffic injuries, cuts, machine injuries, burns, and violence were the other common causes of injury disability. About 30% of the people identified with an injury-related disability mentioned that they don’t use public transports, and 65% of them mentioned this is because of their disability. About 37% people reported that they had lost their job because of the disability. Injury share the significant cause of disability in Bangladesh. Fall, road traffic injury and cuts are the common causes of injury-related disabilities.\u0000Bangabandhu Sheikh Mujib Medical University Journal 2022;15(4):16-21","PeriodicalId":8681,"journal":{"name":"Bangabandhu Sheikh Mujib Medical University Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42740670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-05DOI: 10.3329/bsmmuj.v15i4.64255
M. Zaman
Abstract not available Bangabandhu Sheikh Mujib Medical University Journal 2022;15(4):1
摘要不可用Bangabandhu Sheikh Mujib医科大学学报2022；15（4）：1
{"title":"The ethics of plagiarism","authors":"M. Zaman","doi":"10.3329/bsmmuj.v15i4.64255","DOIUrl":"https://doi.org/10.3329/bsmmuj.v15i4.64255","url":null,"abstract":"Abstract not available\u0000Bangabandhu Sheikh Mujib Medical University Journal 2022;15(4):1\u0000 ","PeriodicalId":8681,"journal":{"name":"Bangabandhu Sheikh Mujib Medical University Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42252148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-05DOI: 10.3329/bsmmuj.v15i4.64152
Sanjida Ahmed, K. Fatema, G. Kundu, S. T. Alam, Rebecca Sultana, Nahid Neela, S. Sultana, Z. Ferdous, Bikush Chandra Paul, Rumana Sultana, K. Poddar, S. Akhter
This cross-sectional study was carried out at the department of Pediatric Neurology, Institute of Pediatric Neurodisorder and Autism, Bangabandhu Sheikh Mujib Medical University, Dhaka with the aim to assess the relationship between gross motor function and MRI findings in children with cerebral palsy. The duration of the study was 12 months. All the cerebral palsy cases who met the selection criteria were enrolled. Detailed history taking and physical examination was done. The gross motor function of all cases was evaluated according to Gross Motor Function Classification System- Expanded and Revised (GMECS-E and R). Magnetic resonance imaging of brain was done in all enrolled patients and reports were evaluated. MRI findings were classified as maldevelopment, cortical and subcortical gray matter lesion, periventricular white matter injury, basal ganglia lesion, normal and other findings. A total of 45 children with cerebral palsy aged between 2 to 12 years were included in this study. Mean age of the children was 4.73 (+3.17) years. Male were 31 and female were 14 in number. Functionally majority patients were in GMFCS level IV (26.7%) and level V (20%). MRI findings were abnormal in 35 (77.78%) cases. Most common abnormal MRI finding was cortical and subcortical grey matter lesions 22 (48.9%). This study revealed that cortical and subcortical gray matter lesions were significantly associated with higher level of GMFCS (IV-V) (P=0.038) and maldevelopment of brain were also significantly associated with higher level of GMFCS (P=0.01). Normal MRI findings had significant association with mild to moderate GMFCS level (I-III) (P=0.012). From this study significant relationship was found between gross motor function and MRI of brain findings in children with cerebral palsy. Bangabandhu Sheikh Mujib Medical University Journal 2022;15(4):8-15
{"title":"Relationship between gross motor function and magnetic resonance imaging findings in children with cerebral palsy","authors":"Sanjida Ahmed, K. Fatema, G. Kundu, S. T. Alam, Rebecca Sultana, Nahid Neela, S. Sultana, Z. Ferdous, Bikush Chandra Paul, Rumana Sultana, K. Poddar, S. Akhter","doi":"10.3329/bsmmuj.v15i4.64152","DOIUrl":"https://doi.org/10.3329/bsmmuj.v15i4.64152","url":null,"abstract":"This cross-sectional study was carried out at the department of Pediatric Neurology, Institute of Pediatric Neurodisorder and Autism, Bangabandhu Sheikh Mujib Medical University, Dhaka with the aim to assess the relationship between gross motor function and MRI findings in children with cerebral palsy. The duration of the study was 12 months. All the cerebral palsy cases who met the selection criteria were enrolled. Detailed history taking and physical examination was done. The gross motor function of all cases was evaluated according to Gross Motor Function Classification System- Expanded and Revised (GMECS-E and R). Magnetic resonance imaging of brain was done in all enrolled patients and reports were evaluated. MRI findings were classified as maldevelopment, cortical and subcortical gray matter lesion, periventricular white matter injury, basal ganglia lesion, normal and other findings. A total of 45 children with cerebral palsy aged between 2 to 12 years were included in this study. Mean age of the children was 4.73 (+3.17) years. Male were 31 and female were 14 in number. Functionally majority patients were in GMFCS level IV (26.7%) and level V (20%). MRI findings were abnormal in 35 (77.78%) cases. Most common abnormal MRI finding was cortical and subcortical grey matter lesions 22 (48.9%). This study revealed that cortical and subcortical gray matter lesions were significantly associated with higher level of GMFCS (IV-V) (P=0.038) and maldevelopment of brain were also significantly associated with higher level of GMFCS (P=0.01). Normal MRI findings had significant association with mild to moderate GMFCS level (I-III) (P=0.012). From this study significant relationship was found between gross motor function and MRI of brain findings in children with cerebral palsy.\u0000Bangabandhu Sheikh Mujib Medical University Journal 2022;15(4):8-15","PeriodicalId":8681,"journal":{"name":"Bangabandhu Sheikh Mujib Medical University Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44698295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-05DOI: 10.3329/bsmmuj.v15i4.64151
Gopa Sarkar, S. Paul, R. Chakrabortty, Shamim Ahmed, S. Islam, Shipan Chandra Paul, Debashish Dhar, Kaoser Alam, Shahed Choudhury, M. A. Rayhan, A. M. Hossain, M. A. Rahman
This cross-sectional study was conducted to determine the serum lipid profiles in chronic obstructive pulmonary disease (COPD) patients and its correlation with the severity of COPD in the Department of Respiratory Medicine at Bangabandhu Sheikh Mujib Medical University. A total of 100 spirometric-confirmed cases of COPD were included. Fasting blood samples for lipid profiles were collected. To identify the association between severity of COPD with lipid profiles Pearson’s correlation was used. Further multiple linear regression was done to identify the relation. The mean (standard deviation) age of the patients was 59.0 (10.7)years. The ratio of males and females was 19:1. The mean forced expiratory volume (liters) in 1 second (FEV1) was 55.1 (18.1). Most of the patients had stage II (48%) and stage III (36%) airflow obstruction. Plasma level of total cholesterol and triglyceride tend to increase, statistically non-significant, with stages of COPD. However, the association of plasma lipids becomes statistically significant with FEV1 when the effects of age, BMI, pack-year smoking, duration of illness are accounted in multiple linear regression analysis. Bangabandhu Sheikh Mujib Medical University Journal 2022;15(4):37-41
{"title":"Lipid profile patterns in chronic obstructive pulmonary disease and its correlation with the severity of disease","authors":"Gopa Sarkar, S. Paul, R. Chakrabortty, Shamim Ahmed, S. Islam, Shipan Chandra Paul, Debashish Dhar, Kaoser Alam, Shahed Choudhury, M. A. Rayhan, A. M. Hossain, M. A. Rahman","doi":"10.3329/bsmmuj.v15i4.64151","DOIUrl":"https://doi.org/10.3329/bsmmuj.v15i4.64151","url":null,"abstract":"This cross-sectional study was conducted to determine the serum lipid profiles in chronic obstructive pulmonary disease (COPD) patients and its correlation with the severity of COPD in the Department of Respiratory Medicine at Bangabandhu Sheikh Mujib Medical University. A total of 100 spirometric-confirmed cases of COPD were included. Fasting blood samples for lipid profiles were collected. To identify the association between severity of COPD with lipid profiles Pearson’s correlation was used. Further multiple linear regression was done to identify the relation. The mean (standard deviation) age of the patients was 59.0 (10.7)years. The ratio of males and females was 19:1. The mean forced expiratory volume (liters) in 1 second (FEV1) was 55.1 (18.1). Most of the patients had stage II (48%) and stage III (36%) airflow obstruction. Plasma level of total cholesterol and triglyceride tend to increase, statistically non-significant, with stages of COPD. However, the association of plasma lipids becomes statistically significant with FEV1 when the effects of age, BMI, pack-year smoking, duration of illness are accounted in multiple linear regression analysis.\u0000Bangabandhu Sheikh Mujib Medical University Journal 2022;15(4):37-41 ","PeriodicalId":8681,"journal":{"name":"Bangabandhu Sheikh Mujib Medical University Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44594609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-05DOI: 10.3329/bsmmuj.v15i4.64225
Jasmine Akhter Jahan, S. Islam, Md. Shafikul Alam Tanim, Tasnim Binte Ahmed, Md Rabiul Alam, F. Begum
Epstein Barr virus plays an important role in the pathogenesis of Hodgkin lymphoma. However, the frequency of its association in Bangladeshi people has not been widely studied. The aim of this study was to determine the association of Epstein Barr virus association in Hodgkin Lymphoma through detection of Latent Membrane Protein 1 by immunohistochemistry and serum Epstein Barr virus viral capsid antigen IgG antibody titer by serology. This was a cross-sectional study in purposively selected 45 histologically diagnosed cases of Hodgkin lymphoma at Bangabandhu Sheikh Mujib Medical University, Dhaka, during the period of March 2017 to December 2018. Latent membrane protein 1 was positive in 71.1% of cases of Hodgkin lymphoma. Among these positive cases, 96% of cases had significantly raised titer of serum Epstein Barr virus viral capsid antigen IgG antibody (P<0.0001 obtained by Fisher’s Exact test), which had a male predominance. Mixed cellularity classical Hodgkin lymphoma showed the highest positivity. Bangabandhu Sheikh Mujib Medical University Journal 2022;15(4):32-36
{"title":"Analysis of the association between Epstein Barr virus infection and Hodgkin lymphoma","authors":"Jasmine Akhter Jahan, S. Islam, Md. Shafikul Alam Tanim, Tasnim Binte Ahmed, Md Rabiul Alam, F. Begum","doi":"10.3329/bsmmuj.v15i4.64225","DOIUrl":"https://doi.org/10.3329/bsmmuj.v15i4.64225","url":null,"abstract":"Epstein Barr virus plays an important role in the pathogenesis of Hodgkin lymphoma. However, the frequency of its association in Bangladeshi people has not been widely studied. The aim of this study was to determine the association of Epstein Barr virus association in Hodgkin Lymphoma through detection of Latent Membrane Protein 1 by immunohistochemistry and serum Epstein Barr virus viral capsid antigen IgG antibody titer by serology. This was a cross-sectional study in purposively selected 45 histologically diagnosed cases of Hodgkin lymphoma at Bangabandhu Sheikh Mujib Medical University, Dhaka, during the period of March 2017 to December 2018. Latent membrane protein 1 was positive in 71.1% of cases of Hodgkin lymphoma. Among these positive cases, 96% of cases had significantly raised titer of serum Epstein Barr virus viral capsid antigen IgG antibody (P<0.0001 obtained by Fisher’s Exact test), which had a male predominance. Mixed cellularity classical Hodgkin lymphoma showed the highest positivity.\u0000Bangabandhu Sheikh Mujib Medical University Journal 2022;15(4):32-36","PeriodicalId":8681,"journal":{"name":"Bangabandhu Sheikh Mujib Medical University Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45204955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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