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PERSPECTIVES OF PSYCHOLOGICAL SUPPORT IN FUTURE EXPLORATION MISSIONS 未来探索任务中的心理支持展望
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-01-01 DOI: 10.21687/0233-528x-2022-56-5-5-13
V. Gushchin, O. Ryumin, О.I. Karpova, I. A. Rozanov, D. Shved, A. Yusupova
The paper summarizes the experience of providing the psychological support for orbital space crews, discusses current practices applicable in future exploration missions, and the psychological negative factors in autonomous missions including new promising technologies developed with these factors in mind.
本文总结了为轨道航天员提供心理支持的经验,讨论了适用于未来探索任务的现行做法,以及自主任务中的心理负面因素,包括考虑到这些因素而开发的有前景的新技术。
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引用次数: 0
IMITATIVE VIRTUAL REALITY-BASED MODELING OF THE MODES OF PILOTED VEHICLE CONTROL ON A LUNAR STATION TO INVESTIGATE OPERATOR'S ACTIVITY IN ISOLATION STUDIES 基于仿真虚拟现实技术的月球站飞行器控制模式建模,以调查操作员在隔离研究中的活动
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-01-01 DOI: 10.21687/0233-528x-2022-56-5-14-28
Y. Bubeev, V. Usov, A. Polyakov, М.V. Mikhaylyuk
The survey is focused on the applicability of virtual reality(VR) and 3D immersive technologies for isolation studies of the human-robot interaction during intravehicular activities (IVA) and scenarios of pilotless vehicles (PVs) operations on a lunar station. The investigation resulted in covering the prototyped multicopter drones for inspecting closed environments on Earth and future creation of appropriate VR models, and proposing off-line PVs analogous to the NASA Free-Flyers Units Astrobee, and VirSim system for use on the lunar station. The imitative VR models and suggested research tasks include the following: 1) PVs scenarios, routing and scheduling, 2) modeling autonomous navigation and control (local positioning and navigation) inside the station, 3) manual piloting, 4) virtual and real control panels, 5) comparison of displays representing PVs cameras stream, 2D-electronic maps and real-time 3D-image, 6) PVs scenarios for potential danger to the lunar station, and support of response to unexpected events. Knowledge from the isolation studies can substantiate guidelines on PVs operations aboard habitable lunar stations.
该调查的重点是虚拟现实(VR)和3D沉浸式技术在车辆内活动(IVA)期间人机交互隔离研究和无人驾驶车辆(pv)在月球站操作场景中的适用性。调查结果涵盖了用于检查地球封闭环境的多架无人机原型和未来创建适当的VR模型,并提出了类似于美国宇航局自由飞行单位Astrobee的离线pv,以及用于月球站的VirSim系统。模拟的VR模型和建议的研究任务包括:1)pv场景、路由和调度,2)建立站内自主导航和控制(局部定位和导航)模型,3)手动驾驶,4)虚拟和真实控制面板,5)pv摄像机流、2d电子地图和实时3d图像显示的比较,6)pv场景对月球站潜在危险的预测,以及对突发事件的响应支持。从隔离研究中获得的知识可以证实pv在可居住的月球站上的操作指南。
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引用次数: 0
EPIDEMIOLOGICAL INVESTIGATION BASED ON ANALYSIS OF MORTALITY AMONG CIVIL PILOTS OF THE RUSSIAN FEDERATION 基于俄罗斯联邦民用飞行员死亡率分析的流行病学调查
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-01-01 DOI: 10.21687/0233-528x-2022-56-4-83-88
I. Bukhtiyarov, E. Zibarev, K. Betts
The paper presents first results of an epidemiological investigation concerned with mortality among Russian civil pilots fulfilled in 2021. Object was a cohort of former pilots selected in the database of the Pension Fund of the Russian Federation since 1991. Each one in the cohort had more than 6 000 flight hours and retired on a pension at the age of 35 the earliest. Mortality was analyzed in the timeframe of 2015 to 2019. Since the RFPF does not contain information about cause of death, the mortality rates were calculated without regard for the cause. As of 31.12.2019, out of 18 254 former pilots in the cohort 1381 (7.6 %) were dead and 16 873 (92.4 %) were alive; total number of person-year observations made up 78 453.7. For the period between 2015 and 2019, the age-standardized mortality factor for pilots was 164.8 per 10 000 which is 31.3 % less when compared to the male population in Russia (238.9 per 10 000), p < 0.05. The risk of death for any reason among former pilots was reliably less in comparison to the male population in Russia: odds ratio is equal to 0.68 within the 95 % confidence interval of 0.56–0.83. Comparatively low death risk for pilots is attributed to the effect of healthy employee, more careful professional selection, high level of medical care, and well-being. However, for the majority of flights the uncontrolled risk of tumor dictates the necessity of further prospective investigations of mortality among civil pilots.
本文介绍了2021年完成的关于俄罗斯民用飞行员死亡率的流行病学调查的初步结果。对象是自1991年以来在俄罗斯联邦养恤基金数据库中选出的前飞行员队列。这个队列中的每个人都有超过6000个飞行小时,最早在35岁时退休。在2015年至2019年的时间框架内分析了死亡率。由于RFPF不包含关于死亡原因的信息,死亡率的计算不考虑死因。截至2019年12月31日,在18254名前飞行员中,1381名(7.6%)死亡,16873名(92.4%)活着;人年观测总数为78 453.7次。2015年至2019年期间,飞行员的年龄标准化死亡率为164.8 / 10000,比俄罗斯男性人口(238.9 / 10000)低31.3%,p < 0.05。与俄罗斯男性人口相比,前飞行员因任何原因死亡的风险确实更低:在0.56-0.83的95%置信区间内,优势比等于0.68。飞行员相对较低的死亡风险归因于健康的员工,更仔细的专业选择,高水平的医疗保健和福利的影响。然而,对于大多数飞行而言,肿瘤的不可控风险决定了对民用飞行员死亡率进行进一步前瞻性调查的必要性。
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引用次数: 0
TOXICOLOGY ISSUES OF LUNAR DUST EFFECTS ON BIOLOGICAL OBJECTS (LITERATURE REVIEW) 月球尘埃对生物物体影响的毒理学问题(文献综述)
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-01-01 DOI: 10.21687/0233-528x-2022-56-5-29-37
M.Yu. Barantseva, L. N. Mukhamedieva, D. Ozerov, A. A. Pakhomova, P. V. Lashukov, I. A. Grabeklis
Long-term lunar missions will require a toxicological and hygienic assessment of the biological impact of lunar dust on humans, as one of the main factors limiting the duration of human stay on the lunar surface. This review summarizes the results of scientific research aimed at studying the acute and chronic effects of lunar dust and its imitators when inhaled and intratracheally administered to animals. The analysis of the biological activity of the particles after their penetration into the respiratory tract and lung tissue was carried out. Based on the modern understanding of the pathogenesis of pulmonary fibrosis, a hypothesis was formulated for the development of toxic damage to the lungs when exposed to lunar dust: mechanical damage to the alveolar epithelium by dust particles, increased microvascular permeability, local and systemic autoimmune inflammatory reactions, activation of cytokine regulation of the inflammatory and fibroplastic process in the lungs and heart.
长期月球任务将需要对月球尘埃对人类的生物影响进行毒理学和卫生评估,这是限制人类在月球表面停留时间的主要因素之一。本文综述了有关月尘及其仿制品吸入和经气管给药对动物急性和慢性影响的科学研究结果。对颗粒进入呼吸道和肺组织后的生物活性进行了分析。基于对肺纤维化发病机制的现代理解,对暴露于月尘时肺毒性损伤的发展提出了一个假设:尘颗粒对肺泡上皮的机械损伤,微血管通透性增加,局部和全身自身免疫炎症反应,激活细胞因子调节肺和心脏的炎症和纤维化过程。
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引用次数: 0
CONTRAST SENSITIVITY AND OCULAR TREMULOUS MICRO-MOTIONS: A MODEL STUDY OF CHANGED GRAVITY EFFECTS ON VISUAL PERCEPTION 对比敏感度和眼球震颤微运动:重力变化对视觉感知影响的模型研究
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-01-01 DOI: 10.21687/0233-528x-2022-56-6-23-30
I. Shoshina, D. Kotova, I. Zelenskaya, S. Lyapunov, I. Lyapunov, M. Bekreneva, E. Tomilovskaya
Visual contrast sensitivity and tremulous micro-movements of eyes were evaluated in 10 human subjects (mean age 30.8 ± 4/6 yrs) volunteered for dry immersion (DI) as a model of the physiological effects of microgravity. Contrast sensitivity was registered using visocontrastmetry with presentation of the Gabor patches with spatial frequency 0.4, 1.0, 3.0, 6.0 and 10.0 c/deg. Amplitude and frequency of eye tremulous movements were measured using a high-frequency optical tweezer. Measurements were performed a day prior to immersion, on DI days 1, 3, 5 and 7, and on the next day after the DI completion. Contrast sensitivity was found altered within both the low and high spatial frequencies; ocular micro-motion amplitudes changed within a wide range. At this point in time, these findings are a step forward in search for a method of objective assessment of the central nervous system functioning in a changed environment.
我们对10名志愿者(平均年龄30.8±4/6岁)进行了视觉对比敏感度和眼球震颤微运动的评估,并将其作为微重力生理效应的模型。对比灵敏度采用视觉对比法,呈现空间频率为0.4、1.0、3.0、6.0和10.0 c/℃的Gabor斑块。用高频光镊测量眼球震颤运动的幅度和频率。测量分别在浸泡前一天、DI第1、3、5和7天以及DI完成后第二天进行。对比灵敏度在低、高空间频率范围内均发生改变;眼微动幅度变化幅度较大。在这个时间点上,这些发现是向前迈进了一步,寻找一种客观评估中枢神经系统在变化环境中的功能的方法。
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引用次数: 0
MEDICO-PSYCHOLOGICAL CORRECTION OF EMOTIONAL STRESS WITH HYPERVENTILATION: ASSESSMENT OF CLINICAL EFFECTS AND INDICATIONS FOR APPLICATION TO PILOTS AND COMBATANTS 过度通气对情绪应激的医学-心理矫正:临床效果评估及应用于飞行员和战斗人员的适应症
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-01-01 DOI: 10.21687/0233-528x-2022-56-2-54-63
I. V. Ivanov, A.A. Milanin, О.P. Zhelty, Yu.V. Stas
We analyzed psychotherapeutic effectiveness of and individual clinical reactions to hyperventilation sessions used for emotional stress correction in 517 patients including 211 pilots and 306 war veterans at the age of 22 to 52 years. The hyperventilation method was recommended for pilots' treatment in hospitals and rehabilitation centers. However, the method may provoke convulsive activities in the brain and personal disorientation and, therefore, should be prescribed on the clinical evidence of benefit to an individuum with post-traumatic stress disorders, and lack of contraindications.
我们分析了517例患者(包括211名飞行员和306名22 - 52岁的退伍军人)对过度通气用于情绪压力矫正的心理治疗效果和个人临床反应。在医院和康复中心的飞行员治疗中,推荐使用过度通气方法。然而,该方法可能引起大脑抽搐活动和个人定向障碍,因此,应根据对创伤后应激障碍患者有益的临床证据和缺乏禁忌症来开处方。
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引用次数: 0
ON THE SUBJECT OF SUBSTANTIATING COEFFICIENTS КМimAND КМdel CHARACTERIZING MODIFICATION OF THE ORGANISM RESPONSE TO RADIATION IMMEDIATELY OR IN DELAYED PERIODS DUE TO THE COMBINED ACTION OF THE STRESSFUL FACTORS IN EXTENDED ORBITAL AND EXPLORATION MISSIONS 关于证实系数的主题КМimAND КМdel表征生物体对辐射反应的立即或延迟的变化,由于在延长的轨道和探索任务中压力因素的共同作用
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-01-01 DOI: 10.21687/0233-528x-2022-56-4-5-20
A. Shafirkin, A. Vasin, S. Tatarkin
Analysis of the huge array of experimental data on the effects of radiation and other physical and natural factors in space missions enabled substantiation of the coefficient of immediate response to radiation (КМim) in context of the risk to cosmonaut's health and efficiency. The КМim value lies with the range of 0.8 – 1.3. Currently, KMim can be taken equal to 1.0 owing to rapid cell recovery in the radiation sensitive bone marrow, GIT, lens epithelium, and brain cortex neurons during prolonged exposure to protons of the solar cosmic rays. The authors validate the modification coefficient for a delayed response (КМdel) presuming probable aggravating effects of air chemical contamination and weightlessness. The КМdel value was established using a calculated overall logarithmic index to quantify the level of stress to the body regulation systems, and functional reserve reduction. Acetone, acetaldehyde and ethanol vapors at maximal admissible concentrations may increase KMdel up to 1.5. Moreover, KMdel should be taken equal to 2.0 on the evidence that synergy of microgravity and GCR heavy nuclei threatens with morphological and functional CNS disorders, vascular damages and cardiovascular diseases and lifespan reduction.
对关于空间任务中辐射及其他物理和自然因素影响的大量实验数据的分析,使在对宇航员健康和效率构成风险的情况下确定对辐射的即时反应系数(КМim)。КМim的取值范围为0.8 - 1.3。目前,由于长时间暴露在太阳宇宙射线的质子下,对辐射敏感的骨髓、GIT、晶状体上皮和大脑皮层神经元的细胞恢复迅速,KMim可以取为1.0。作者验证了延迟响应的修正系数(КМdel),假设空气化学污染和失重可能会加重影响。使用计算的总体对数指数来确定КМdel值,以量化身体调节系统的压力水平和功能储备减少。丙酮、乙醛和乙醇蒸气在最大允许浓度下可使kmodel升高至1.5。此外,微重力和GCR重核的协同作用对中枢神经系统的形态和功能紊乱、血管损伤和心血管疾病的威胁以及寿命缩短的证据应使kmodel等于2.0。
{"title":"ON THE SUBJECT OF SUBSTANTIATING COEFFICIENTS КМimAND КМdel CHARACTERIZING MODIFICATION OF THE ORGANISM RESPONSE TO RADIATION IMMEDIATELY OR IN DELAYED PERIODS DUE TO THE COMBINED ACTION OF THE STRESSFUL FACTORS IN EXTENDED ORBITAL AND EXPLORATION MISSIONS","authors":"A. Shafirkin, A. Vasin, S. Tatarkin","doi":"10.21687/0233-528x-2022-56-4-5-20","DOIUrl":"https://doi.org/10.21687/0233-528x-2022-56-4-5-20","url":null,"abstract":"Analysis of the huge array of experimental data on the effects of radiation and other physical and natural factors in space missions enabled substantiation of the coefficient of immediate response to radiation (КМim) in context of the risk to cosmonaut's health and efficiency. The КМim value lies with the range of 0.8 – 1.3. Currently, KMim can be taken equal to 1.0 owing to rapid cell recovery in the radiation sensitive bone marrow, GIT, lens epithelium, and brain cortex neurons during prolonged exposure to protons of the solar cosmic rays. The authors validate the modification coefficient for a delayed response (КМdel) presuming probable aggravating effects of air chemical contamination and weightlessness. The КМdel value was established using a calculated overall logarithmic index to quantify the level of stress to the body regulation systems, and functional reserve reduction. Acetone, acetaldehyde and ethanol vapors at maximal admissible concentrations may increase KMdel up to 1.5. Moreover, KMdel should be taken equal to 2.0 on the evidence that synergy of microgravity and GCR heavy nuclei threatens with morphological and functional CNS disorders, vascular damages and cardiovascular diseases and lifespan reduction.","PeriodicalId":8683,"journal":{"name":"Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67953839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MARKERS OF THE OCCUPATIONAL HEALTH RISKS TO FLIGHT PERSONNEL OF THE STATE-OWNED AIRLINERS ACCORDING TO THE DATA OF PILOTS MEDICAL CERTIFICATION 根据飞行员体检合格证数据分析国有航空公司飞行人员职业健康风险指标
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-01-01 DOI: 10.21687/0233-528x-2022-56-6-51-59
V. S. Vovkodav
The paper discusses the occupational risks for flight crews of the state-owned airliners. In the period of 2004–2009, prevalence of the cardiovascular diseases was low and increased in 2010–2015, as well as relative risks of the cardiovascular, ear and mastoid diseases. The period of 2016–2020 was marked by a high risk of urogenital diseases, as the probability of these diseases made up 2.2 and the etiological percent amounted to 50 %. The system of flight personnel health monitoring has been time-proved. The author points out the areas of research to be focused on in order to improve the crew work environment and calls for introduction of the informatics technology in the crew health monitoring system.
本文对国有航空公司机组人员的职业风险进行了探讨。2004-2009年期间,心血管疾病患病率较低,2010-2015年有所增加,心血管、耳部和乳突疾病的相对风险也有所增加。2016-2020年期间,泌尿生殖系统疾病的风险很高,因为这些疾病的概率为2.2%,病因率为50%。飞行人员健康监测系统已经过实践验证。指出了改善机组工作环境需要重点研究的领域,并呼吁在机组健康监测系统中引入信息技术。
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引用次数: 0
ADMINISTRATION IN EXTREME CONDITIONS OF MEDICAMENTS BASED ON NICOTINIC ACID AND ITS DERIVATIVES 以烟酸及其衍生物为基础的药物在极端条件下的施用
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-01-01 DOI: 10.21687/0233-528x-2022-56-4-35-43
V. Yasnetsov, D. E. Kaurova
The literary review encompasses the experimental and clinical evidence of the potency of Russian medicaments nicotinoyl gamma-aminobutyric acid (picamilon), hydroxyzine nicotinoyl glutamate calcium (ampasse), and combineddrug cytoflavin containing nicotinic acid and its derivatives in extreme conditions. Analysis shows that these medicaments and nicotinic acid derivatives protect tangibly from acute and chronic hypoxia of varying genesis, hypo- and hyperthermia, hypokinesia etc. To increase potency and safety of medical care after exposure to extreme factors the search for other nicotinic acid derivatives should be furthered.
文献综述包括俄罗斯药物烟酰γ -氨基丁酸(picamilon),羟嗪烟酰谷氨酸钙(ampasse)和含有烟酸及其衍生物的联合药物细胞黄素在极端条件下的效力的实验和临床证据。分析表明,这些药物和烟酸衍生物对不同原因的急慢性缺氧、低体温和高热、运动不足等有明显的保护作用。为了提高暴露于极端因素后医疗保健的效力和安全性,应进一步寻找其他烟酸衍生物。
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引用次数: 0
OPTIMIZATION OF THE PLANT ILLUMINATION SYSTEM STABILIZING OXYGEN CONCENTRATION IN THE GAS MEDIUM WITHIN A PROTOTYPED BIOTECHNICAL CREW LIFE SUPPORT SYSTEM 植物照明系统的优化,稳定了生物技术船员生命维持系统原型中气体介质中的氧气浓度
Q4 Biochemistry, Genetics and Molecular Biology Pub Date : 2022-01-01 DOI: 10.21687/0233-528x-2022-56-5-102-110
Y. Berkovich, О.А. Shalopanova, А.А. Buriak
We validated an approach to optimization of the higher plant illumination system within a biotechnical life support system (BTLSS) in order to reduce power consumption and equivalent harvest mass. The challenge was to stabilize oxygen concentration in the air of a pressurized compartment. To compare different approaches to power consumption optimization, we used publications on a study in which BTLSS with a 27 m2 cultivation area provided leaf vegetables (Chinese cabbage) to 2 human subjects. Time course of the daily energy and O2 consumption was divided into 5 periods according to specified levels of loading. In context of a Moon mission scenario, the optimal photon flux density and white-red light ratios were calculated using regression models for each day between vegetation days 8 and 14. Experimentally obtained models of photosynthetic productivity were used to calculate a daily lighting level required to produce oxygen in the amount sufficient for the crew. It was shown that this method of O2 stabilization makes possible, within 7 days, power consumption reduction by 68 % and increase of the coefficient of light energy consumption by harvest in 2.3 times as compared to the control growing under continuous invariable illumination. Moreover, equivalent mass of the illumination system reduced 30 % as compared to the control.
我们验证了一种在生物技术生命支持系统(BTLSS)中优化高等植物照明系统的方法,以降低功耗和等效收获质量。挑战在于稳定增压舱空气中的氧气浓度。为了比较不同的功耗优化方法,我们使用了一项研究的出版物,该研究中,种植面积为27平方米的BTLSS为2名人类受试者提供叶菜(大白菜)。根据规定的负荷水平,将每日能量和氧气消耗的时间过程划分为5个时段。在月球任务情景下,利用回归模型计算了植被第8至14天之间每天的最佳光子通量密度和白红光比。通过实验获得的光合作用效率模型被用来计算每天所需的光照水平,以产生足够船员所需的氧气。结果表明,与连续不变光照条件下的对照相比,这种O2稳定方法可在7天内使收获时的耗电量降低68%,光能消耗系数提高2.3倍。此外,与对照组相比,照明系统的等效质量减少了30%。
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引用次数: 0
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Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine
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