Pub Date : 2024-07-01DOI: 10.21608/bvmj.2024.279370.1799
A. Sobeih, Hossam Eldin El Attar, Yassen Abdel-Raoof, mohammed anwar ramadan, M. Helal
Keywords Feline enteritis has significant clinical issues that have an impact on their health. We conducted this study on 30 cats suffering from various types of enteritis affection, including viral, bacterial, and parasitic. The study aimed to assess the clinical, hematological and biochemical alterations in cats with various forms of enteritis. The most prevalent clinical signs seen in all forms of enteritis were diarrhea, vomiting, dehydration, and anorexia. Hematological changes revealed a significant reduction in hemoglobin content and red blood cell count than control values in viral and bacterial enteritis. WBCs count and granulocytes were significantly increased in bacterial enteritis. In viral enteritis, there was a significant decrease in lymphocytes and granulocytes, while in parasitic enteritis, there was a significant increase in eosinophils. Different types of enteritis showed significant increases in total protein, globulin, ALT, ALP, and AST, as well as BUN and creatinine, and significant decreases in Ca, P, Na, Cl, and K ions. There was a significant increase in antioxidant enzyme levels, including GSH-Px and SOD, and a significant increase in MDA, inflammatory cytokines, including IL2 and IL6, and acute phase proteins, including HP and CRP, in all affections. These results highlight the complexity of feline enteritis and the demand for specialized treatment strategies to meet the wide range of clinical, hematological and biochemical changes..
关键词 猫肠炎是影响猫健康的重大临床问题。我们对 30 只患有各种类型肠炎(包括病毒性、细菌性和寄生虫性)的猫进行了研究。研究旨在评估患有各种类型肠炎的猫的临床、血液学和生化变化。各种肠炎最常见的临床症状是腹泻、呕吐、脱水和厌食。血液学变化显示,在病毒性和细菌性肠炎中,血红蛋白含量和红细胞计数比对照值明显降低。细菌性肠炎患者的白细胞计数和粒细胞明显增加。在病毒性肠炎中,淋巴细胞和粒细胞明显减少,而在寄生虫性肠炎中,嗜酸性粒细胞明显增加。不同类型的肠炎显示总蛋白、球蛋白、ALT、ALP 和 AST 以及 BUN 和肌酐显著增加,而 Ca、P、Na、Cl 和 K 离子显著减少。在所有病症中,抗氧化酶(包括 GSH-Px 和 SOD)水平都有明显升高,而 MDA、炎症细胞因子(包括 IL2 和 IL6)以及急性期蛋白(包括 HP 和 CRP)都有明显升高。这些结果突显了猫肠炎的复杂性,以及对专门治疗策略的需求,以满足广泛的临床、血液学和生化变化。
{"title":"Clinical, Hematological and Biochemical Studies on Feline Enteritis","authors":"A. Sobeih, Hossam Eldin El Attar, Yassen Abdel-Raoof, mohammed anwar ramadan, M. Helal","doi":"10.21608/bvmj.2024.279370.1799","DOIUrl":"https://doi.org/10.21608/bvmj.2024.279370.1799","url":null,"abstract":"Keywords Feline enteritis has significant clinical issues that have an impact on their health. We conducted this study on 30 cats suffering from various types of enteritis affection, including viral, bacterial, and parasitic. The study aimed to assess the clinical, hematological and biochemical alterations in cats with various forms of enteritis. The most prevalent clinical signs seen in all forms of enteritis were diarrhea, vomiting, dehydration, and anorexia. Hematological changes revealed a significant reduction in hemoglobin content and red blood cell count than control values in viral and bacterial enteritis. WBCs count and granulocytes were significantly increased in bacterial enteritis. In viral enteritis, there was a significant decrease in lymphocytes and granulocytes, while in parasitic enteritis, there was a significant increase in eosinophils. Different types of enteritis showed significant increases in total protein, globulin, ALT, ALP, and AST, as well as BUN and creatinine, and significant decreases in Ca, P, Na, Cl, and K ions. There was a significant increase in antioxidant enzyme levels, including GSH-Px and SOD, and a significant increase in MDA, inflammatory cytokines, including IL2 and IL6, and acute phase proteins, including HP and CRP, in all affections. These results highlight the complexity of feline enteritis and the demand for specialized treatment strategies to meet the wide range of clinical, hematological and biochemical changes..","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":"124 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141697162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/bvmj.2024.283972.1814
Heba Elsaied Sherif, Y. E. El- Senosi, S. Hussein, Ehab Elzoghby, Mohamed Ahmed Sobh, Sara M. Farrag, Basma Hamed Osman
Keywords Chemotherapeutic drugs, particularly alkylating cytotoxics such as cyclophosphamide (CYP) play a great job in inducing premature ovarian failure (POF). Hormone replacement therapy (HRT) is a widely used medication to improve hormone secretion. However, long-term HRT increases the risk of breast cancer and cardiovascular disease is concerning. Therefore, there is an urgent need to develop a safe and effective treatment for POF. Bone Marrow-(BM-MSCs) and Umbilical Cord -(UC-MSCs) derived stem cells (SCs) were isolated and identified from healthy rats. For POF induction, CYP (200mg/Kg b.wt) injected (i.p) into CYP, CYP+BMSCs, and CYP+UCMSCs followed by another dose (10mg/ b.wt, i.p) after one week. The normal control (NC) group were injected with saline. After two weeks of POF induction MSCs (1 × 10 6 cells/ml) of media were transplanted into POF rats through tail-vein. The effects of MSCs transplantation to POF were evaluated through sex hormones, iron, and complete blood count (CBC) analysis. POF-induced rats showed a significant increase in serum FSH and LH, with marked decrease in anti-Mullerian hormone (AMH) and estradiol (E2). Obvious increase in serum iron level observed in CYP group compared to the NC. Moreover, POF-induced rats displayed leucopenia, erythrocytopenia, and thrombocytopenia with a significant reduction in Hb, PCV, MCV, MCH, and MCHC compared to the NC. Administration of MSCs to CYP-injured rats significantly improved female reproductive hormones disturbances, iron, and hemogram. It was suggested that MSCs was a potential approach for improving sex hormones, iron, and hematological alterations, and potentially promoting the restoration of CYP-induced POF. Cyclophosphamide
{"title":"Mesenchymal stem cells promote the repair of chemotherapy-induced premature ovarian failure in female rats","authors":"Heba Elsaied Sherif, Y. E. El- Senosi, S. Hussein, Ehab Elzoghby, Mohamed Ahmed Sobh, Sara M. Farrag, Basma Hamed Osman","doi":"10.21608/bvmj.2024.283972.1814","DOIUrl":"https://doi.org/10.21608/bvmj.2024.283972.1814","url":null,"abstract":"Keywords Chemotherapeutic drugs, particularly alkylating cytotoxics such as cyclophosphamide (CYP) play a great job in inducing premature ovarian failure (POF). Hormone replacement therapy (HRT) is a widely used medication to improve hormone secretion. However, long-term HRT increases the risk of breast cancer and cardiovascular disease is concerning. Therefore, there is an urgent need to develop a safe and effective treatment for POF. Bone Marrow-(BM-MSCs) and Umbilical Cord -(UC-MSCs) derived stem cells (SCs) were isolated and identified from healthy rats. For POF induction, CYP (200mg/Kg b.wt) injected (i.p) into CYP, CYP+BMSCs, and CYP+UCMSCs followed by another dose (10mg/ b.wt, i.p) after one week. The normal control (NC) group were injected with saline. After two weeks of POF induction MSCs (1 × 10 6 cells/ml) of media were transplanted into POF rats through tail-vein. The effects of MSCs transplantation to POF were evaluated through sex hormones, iron, and complete blood count (CBC) analysis. POF-induced rats showed a significant increase in serum FSH and LH, with marked decrease in anti-Mullerian hormone (AMH) and estradiol (E2). Obvious increase in serum iron level observed in CYP group compared to the NC. Moreover, POF-induced rats displayed leucopenia, erythrocytopenia, and thrombocytopenia with a significant reduction in Hb, PCV, MCV, MCH, and MCHC compared to the NC. Administration of MSCs to CYP-injured rats significantly improved female reproductive hormones disturbances, iron, and hemogram. It was suggested that MSCs was a potential approach for improving sex hormones, iron, and hematological alterations, and potentially promoting the restoration of CYP-induced POF. Cyclophosphamide","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":"9 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141708818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/bvmj.2024.284390.1815
Mohamed A. Abd El-Hameed, Hemmat M. Ibrahim, Reham A. Amin
.
.
{"title":"Quality and chemical composition of meat recovered from bovine carcasses lightly infested with cysticercosis","authors":"Mohamed A. Abd El-Hameed, Hemmat M. Ibrahim, Reham A. Amin","doi":"10.21608/bvmj.2024.284390.1815","DOIUrl":"https://doi.org/10.21608/bvmj.2024.284390.1815","url":null,"abstract":".","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":"114 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141712884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/bvmj.2024.283262.1808
Wesam Dawam, Mai Elsheikh, Shimaa N. Edris, Ali Osman, M. Sitohy, I. Sabike
.
.
{"title":"Soybean 11S globulin spray boosts chilled shrimp shelf-life, physicochemical, and sensory attributes beyond twelve days","authors":"Wesam Dawam, Mai Elsheikh, Shimaa N. Edris, Ali Osman, M. Sitohy, I. Sabike","doi":"10.21608/bvmj.2024.283262.1808","DOIUrl":"https://doi.org/10.21608/bvmj.2024.283262.1808","url":null,"abstract":".","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":"10 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141704433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/bvmj.2024.280836.1803
Aya Mohamed Ahmed, F. Mohamed, Gehan Sayed eltanany, Shimaa N. Edris
Keywords Food safety is a global priority due to foodborne pathogens contamination. This study determined the prevalence of Aerobic mesophilic bacteria count (AMB), Staphylococcus aureus, Salmonella spp., E. coli and Listeria monocytogenes in imported chilled and frozen beef in Egypt. The experimental results revealed that the AMB (cfu/g) in chilled samples varied from 5.3×10 4 to 4.7×10 6 , with an average of 8.35×10 5 ±1.06. In contrast, for frozen samples, the range was from 9.7×10 3 to 1.5×10 6 , with an average of 3.11×10 5 ±0.29. Staphylococcus aureus was found in 24 % of chilled beef samples and 16 % of imported frozen beef samples. The prevalence of Salmonella spp. was identified in 5% of chilled beef samples and 3% of imported frozen beef samples . Additionally, Escherichia coli was identified in and 14% of chilled samples and 8% of frozen samples. The presence of L. monocytogenes was identified in 3% of chilled beef samples and 1% of frozen samples. The results obtained validated the inadequate bacteriological quality of certain imported chilled and frozen meats sold in the markets of Cairo and Qalyubia. This quality deficiency is a result of unclean transportation practices that continue to the retail levels. Chilled comprehensive findings, it can be inferred that imported chilled and frozen beef poses a substantial bacteriological public health risk and requires specific control measures.
{"title":"Prevalence of some Foodborne Pathogens (FBPs) in imported chilled and frozen beef in Egypt","authors":"Aya Mohamed Ahmed, F. Mohamed, Gehan Sayed eltanany, Shimaa N. Edris","doi":"10.21608/bvmj.2024.280836.1803","DOIUrl":"https://doi.org/10.21608/bvmj.2024.280836.1803","url":null,"abstract":"Keywords Food safety is a global priority due to foodborne pathogens contamination. This study determined the prevalence of Aerobic mesophilic bacteria count (AMB), Staphylococcus aureus, Salmonella spp., E. coli and Listeria monocytogenes in imported chilled and frozen beef in Egypt. The experimental results revealed that the AMB (cfu/g) in chilled samples varied from 5.3×10 4 to 4.7×10 6 , with an average of 8.35×10 5 ±1.06. In contrast, for frozen samples, the range was from 9.7×10 3 to 1.5×10 6 , with an average of 3.11×10 5 ±0.29. Staphylococcus aureus was found in 24 % of chilled beef samples and 16 % of imported frozen beef samples. The prevalence of Salmonella spp. was identified in 5% of chilled beef samples and 3% of imported frozen beef samples . Additionally, Escherichia coli was identified in and 14% of chilled samples and 8% of frozen samples. The presence of L. monocytogenes was identified in 3% of chilled beef samples and 1% of frozen samples. The results obtained validated the inadequate bacteriological quality of certain imported chilled and frozen meats sold in the markets of Cairo and Qalyubia. This quality deficiency is a result of unclean transportation practices that continue to the retail levels. Chilled comprehensive findings, it can be inferred that imported chilled and frozen beef poses a substantial bacteriological public health risk and requires specific control measures.","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":"25 5‐6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141689084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/bvmj.2024.283865.1813
Mohamed A. Abd El-Hameed, Hemmat M. Ibrahim, Reham A. Amin
{"title":"The prevalence detection of Cysticercus bovis in slaughtered cattle in El-Bassatine abattoir, Cairo, Egypt","authors":"Mohamed A. Abd El-Hameed, Hemmat M. Ibrahim, Reham A. Amin","doi":"10.21608/bvmj.2024.283865.1813","DOIUrl":"https://doi.org/10.21608/bvmj.2024.283865.1813","url":null,"abstract":"","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":"36 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141712772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/bvmj.2024.282792.1807
Mai Elsheikh, Wesam Dawam, Shimaa N. Edris, Ali Osman, M. Sitohy, I. Sabike
Keywords Shrimp preservation is of interest to food scientists and processors because of their restricted shelf life caused by microbial spoilage, black spot formation, and the associated financial losses and food safety risks. Current study was conducted to determine the preservative impacts of Cowpea ( Vigna unguiculata ) 11S globulin (CPEG) spray on tiger shrimp ( Penaeus monodon ) shelf-life and physicochemical characteristics, as well as optimum field preservative levels. Fresh peeled tiger shrimp were sprayed with either 100µg/ml (CPEG1) or 200µg/ml (CPEG2) of CPEG at a rate of 2 ml/100 gm and refrigerated at 2±0.5°C. The control shrimp received only sterile distilled water. After 12 storage days, CPEG2 sprayed shrimp displayed a steadily raising pH trend, reaching 7.3, whereas control and CPEG1 sprayed shrimp demonstrated a V-pH curve. Though was not entirely significant, but 200 µg/ml of CPEG spray improved shrimp WHC and drip loss attributes. Compared to the apparent increasing curves of control shrimp's native microbial curves, which culminated in clear spoiling on the eighth day, CPEG-treated shrimp at both doses did not exceed 6 log cfu/gm for the entire twelve-day chilling period. Also, both CPEG levels exhibited a significant antioxidant impact compared to the control. The retarding effect of CPEG on treated shrimp native microbial curves and malondialdehyde was dose dependent. Conclusively, both CPEG levels kept the fresh tiger shrimp's organoleptic aspects and postponed the spoilage beyond twelve-days. Therefore, the shrimp's shelf-life can potentially be extended while preserving its safety and quality by using the CPEG spray, which works best at 200 µg/ml.
{"title":"Cowpea 11S globulin spray quadruples shrimp shelf-life and maintains freshness","authors":"Mai Elsheikh, Wesam Dawam, Shimaa N. Edris, Ali Osman, M. Sitohy, I. Sabike","doi":"10.21608/bvmj.2024.282792.1807","DOIUrl":"https://doi.org/10.21608/bvmj.2024.282792.1807","url":null,"abstract":"Keywords Shrimp preservation is of interest to food scientists and processors because of their restricted shelf life caused by microbial spoilage, black spot formation, and the associated financial losses and food safety risks. Current study was conducted to determine the preservative impacts of Cowpea ( Vigna unguiculata ) 11S globulin (CPEG) spray on tiger shrimp ( Penaeus monodon ) shelf-life and physicochemical characteristics, as well as optimum field preservative levels. Fresh peeled tiger shrimp were sprayed with either 100µg/ml (CPEG1) or 200µg/ml (CPEG2) of CPEG at a rate of 2 ml/100 gm and refrigerated at 2±0.5°C. The control shrimp received only sterile distilled water. After 12 storage days, CPEG2 sprayed shrimp displayed a steadily raising pH trend, reaching 7.3, whereas control and CPEG1 sprayed shrimp demonstrated a V-pH curve. Though was not entirely significant, but 200 µg/ml of CPEG spray improved shrimp WHC and drip loss attributes. Compared to the apparent increasing curves of control shrimp's native microbial curves, which culminated in clear spoiling on the eighth day, CPEG-treated shrimp at both doses did not exceed 6 log cfu/gm for the entire twelve-day chilling period. Also, both CPEG levels exhibited a significant antioxidant impact compared to the control. The retarding effect of CPEG on treated shrimp native microbial curves and malondialdehyde was dose dependent. Conclusively, both CPEG levels kept the fresh tiger shrimp's organoleptic aspects and postponed the spoilage beyond twelve-days. Therefore, the shrimp's shelf-life can potentially be extended while preserving its safety and quality by using the CPEG spray, which works best at 200 µg/ml.","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":"19 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141688735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/bvmj.2024.270979.1790
hadeer youseef, Eman Araby, Amel El Asely, A. Shaheen, Amany Abbass
Keywords The present research was carried out to evaluate the effect of Sanacore ® GM feed additives on the growth rate, hematological indices, biochemical indicators, anti-oxidative profile, non-specific immune response, and defense of Nile tilapia against Aeromonas veronii ( A. veronii ). Two fish groups of mean initial weight (13.5 ± 1.5g) were randomly allocated in triplicate and fed Sanacore ® GM at a dose of 0 (control) and 5 g/kg diet for a period of 30 days. Fish were challenged by A. veronii at the experimental endpoint and the mortality rate was recorded for 15 days. Fish fed Sanacore ® GM supplemented diet revealed significant increase in final body weight, haemato-biochemical indices (red blood cells, white blood cells, hemoglobin concentration, lymphocytes, neutrophils, serum total protein, and albumin levels), and immunological parameters (phagocytic activity, nitric oxide, lysozyme activity, IgM, and serum bactericidal activity). In addition, the anti-oxidative enzymes activity (superoxide dismutase and glutathione peroxidase) showed meaningful increase in Nile tilapia received Sanacore ® GM incorporated diet. However, catalase enzyme displayed no significant activity ( P > 0.05) in the supplemented group compared to the control group. The relative percentage survival was 100% in the challenged Sanacore ® GM group compared the control. Our finding suggested that Sanacore ® GM might considerably boost final growth rate, haemato-biochemical indices, immune response, anti-oxidative capability of Nile tilapia, as well as disease resistant against pathogenic strains of A. veronii . Aeromonas veronii,
{"title":"Sanacore® GM supplemented feed boosts the haemato-biochemical indices, immune response, anti-oxidative profile, and defense against Aeromonas Vernoii in Nile tilapia (Oreochromis niloticus).","authors":"hadeer youseef, Eman Araby, Amel El Asely, A. Shaheen, Amany Abbass","doi":"10.21608/bvmj.2024.270979.1790","DOIUrl":"https://doi.org/10.21608/bvmj.2024.270979.1790","url":null,"abstract":"Keywords The present research was carried out to evaluate the effect of Sanacore ® GM feed additives on the growth rate, hematological indices, biochemical indicators, anti-oxidative profile, non-specific immune response, and defense of Nile tilapia against Aeromonas veronii ( A. veronii ). Two fish groups of mean initial weight (13.5 ± 1.5g) were randomly allocated in triplicate and fed Sanacore ® GM at a dose of 0 (control) and 5 g/kg diet for a period of 30 days. Fish were challenged by A. veronii at the experimental endpoint and the mortality rate was recorded for 15 days. Fish fed Sanacore ® GM supplemented diet revealed significant increase in final body weight, haemato-biochemical indices (red blood cells, white blood cells, hemoglobin concentration, lymphocytes, neutrophils, serum total protein, and albumin levels), and immunological parameters (phagocytic activity, nitric oxide, lysozyme activity, IgM, and serum bactericidal activity). In addition, the anti-oxidative enzymes activity (superoxide dismutase and glutathione peroxidase) showed meaningful increase in Nile tilapia received Sanacore ® GM incorporated diet. However, catalase enzyme displayed no significant activity ( P > 0.05) in the supplemented group compared to the control group. The relative percentage survival was 100% in the challenged Sanacore ® GM group compared the control. Our finding suggested that Sanacore ® GM might considerably boost final growth rate, haemato-biochemical indices, immune response, anti-oxidative capability of Nile tilapia, as well as disease resistant against pathogenic strains of A. veronii . Aeromonas veronii,","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":"13 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141698471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/bvmj.2024.275730.1797
Ragaa Salah Kawara, Fatma Moawed, Hussein Abd Elmaksoud, Yakout Elsenosi, Omayma R Abo-Zaid
Keywords Lemon balm has many therapeutic effects including antimicrobial activity (anti-parasitic, antibacterial, antiviral, antifungal, etc.). Various studies have shown that Lemon balm possesses a high amount of antioxidant activity through its chemical components including high amount of flavonoids, rosmaric acid, gallic acid and phenolic contents. This study was designed to evaluate the therapeutic effect of Lemon balm extract against hyperthyroidism induced by Eltroxin. Hyperthyroidism was induced by injecting rats with Eltroxin (100 μg/kg/ day) for 14 days. The hyperthyroid rats were orally treated with Lemon balm extract (75 mg/kg/day) at the beginning of the second week of the Eltroxin injection and continued for another week. The levels of TSH , T3 ,T4 and oxidative biomarkers (NO and CAT ) were measured using commercial kits. Thyroid specimens were taken for histopathological examination. Lemon balm extract reversed the effect of Eltroxin on rats and attenuated the thyroid hormones Additionally, Lemon balm extract alleviated the inflammatory response by suppressing the NO and increasing CAT when compared to hyperthyroid group. Accordingly, these results might strengthen the protective effect of Lemon balm extract in a rat model of hyperthyroidism.
{"title":"Ameliorative effect of lemon balm on eltroxin induced-hyperthyroidism in rats","authors":"Ragaa Salah Kawara, Fatma Moawed, Hussein Abd Elmaksoud, Yakout Elsenosi, Omayma R Abo-Zaid","doi":"10.21608/bvmj.2024.275730.1797","DOIUrl":"https://doi.org/10.21608/bvmj.2024.275730.1797","url":null,"abstract":"Keywords Lemon balm has many therapeutic effects including antimicrobial activity (anti-parasitic, antibacterial, antiviral, antifungal, etc.). Various studies have shown that Lemon balm possesses a high amount of antioxidant activity through its chemical components including high amount of flavonoids, rosmaric acid, gallic acid and phenolic contents. This study was designed to evaluate the therapeutic effect of Lemon balm extract against hyperthyroidism induced by Eltroxin. Hyperthyroidism was induced by injecting rats with Eltroxin (100 μg/kg/ day) for 14 days. The hyperthyroid rats were orally treated with Lemon balm extract (75 mg/kg/day) at the beginning of the second week of the Eltroxin injection and continued for another week. The levels of TSH , T3 ,T4 and oxidative biomarkers (NO and CAT ) were measured using commercial kits. Thyroid specimens were taken for histopathological examination. Lemon balm extract reversed the effect of Eltroxin on rats and attenuated the thyroid hormones Additionally, Lemon balm extract alleviated the inflammatory response by suppressing the NO and increasing CAT when compared to hyperthyroid group. Accordingly, these results might strengthen the protective effect of Lemon balm extract in a rat model of hyperthyroidism.","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":"53 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141689905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.21608/bvmj.2024.288584.1825
mohamed osama rateb, Afaf D. Abdelmagid, Omnia Abd elhamid, Alshaimaa Said
ABSTRACT
摘要
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