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The impact of common cleaning solutions on the mechanical properties of clear orthodontic aligners made from PET-G, polyurethane and resin-based materials is of interest. Nanoindentation tests measured elastic modulus, hardness, elastic index and load relaxation after exposure to Retainer Brite®, Fresh Guard® and artificial saliva. The results showed that peroxide-based cleaners significantly degrade aligner properties, while Fresh Guard® causes moderate changes and artificial saliva has minimal effects. Resin-based aligners showed superior chemical stability, making them more resistant to cleaning agents. Thus, mild cleaners are recommended for maintaining aligner performance.

Malocclusion in children often remains unnoticed or underestimated by parents, despite its significant impact on oral function and psychosocial well-being. Therefore, it is of interest to assess parental awareness and practices regarding malocclusion and orthodontic care among 200 parents in Ahmedabad, Gujarat, using a validated bilingual questionnaire. Data revealed that while 75.5% of parents were aware of malocclusion, only 30% knew about orthodontic appliances beyond fixed metal braces and male parents demonstrated significantly higher awareness levels. Most parents (86%) expressed readiness to persuade their child for treatment based on professional advice; yet socioeconomic factors influenced treatment preferences. Thus, that despite moderate awareness, there is a pressing need for targeted public health programs and educational initiatives to enhance parental knowledge and encourage timely orthodontic intervention for children.

Ileostomy is a life-saving procedure often performed in emergency settings for complicated cases such as ileal perforation, particularly due to enteric fever and intestinal tuberculosis. We conducted a prospective study between October 2018 and September 2020, including 57 patients who underwent temporary ileostomy for faecal diversion in emergency laparotomies. The majority of patients were male, with common presenting symptoms being abdominal pain, fever and vomiting. Postoperative complications were frequent, the most common being skin excoriation and ileostomy diarrhoea, while the overall mortality rate was 3.51% and the average hospital stay was 10-14 days. Despite these challenges, temporary ileostomy remains an effective and essential intervention in critically ill patients, with manageable complications and favourable outcomes.

The effect of platelet-rich fibrin (PRF) in improving healing post-impacted mandibular third molar extractions is of interest. Hence, a randomized trial was conducted with 30 patients, comparing outcomes between those treated with PRF and those without. The results demonstrated that PRF significantly reduced pain and swelling and promoted better bone healing, particularly in the early postoperative period. Although benefits plateaued at 6 months, PRF remains a promising adjunct for enhancing recovery in oral surgery.

Total hip arthroplasty is an effective procedure for improving mobility and quality of life, but the comparative functional outcomes of cemented and uncemented techniques remain debated. In this prospective randomised study of 50 patients divided into two equal groups, clinical and radiological assessments were performed preoperatively and at regular intervals up to 4 years. Cemented THR demonstrated superior early outcomes, with significantly better pain relief and Harris Hip Scores at 6 weeks and 3 months. By 6 months, functional outcomes between cemented and uncemented THRs converged, with both groups achieving good-to-excellent results and minimal complications. Cemented implants provide faster early recovery, while the long-term advantages of uncemented implants require further investigation to guide individualised implant selection.

Leveraging QR codes in medical education enhances student motivation, autonomy and engagement. Therefore, it is of interest to evaluate the use of QR codes as educational tools among 106 Phase 3 MBBS students in India, utilizing online resources such as lecture slides and quizzes. Data collected through surveys and focus group discussions revealed that 98.11% of participants were familiar with QR codes. Data indicated improved engagement and convenience in accessing educational content, although opinions varied on their comfort and effectiveness compared to traditional methods. While QR codes enrich learning experiences, challenges like technology access and internet connectivity must be addressed.

Digital health technologies have enhanced cardiac rehabilitation by enabling remote monitoring, personalized feedback and increased patient engagement. This retrospective study analyzed four years of medical records from patients using digital platforms, wearables and teleconsultations. Those using digital tools showed higher adherence, better functional gains and improved risk factor control than those in traditional care. Remote monitoring allowed for earlier detection of clinical changes and timely treatment adjustments, reducing hospital readmissions. Data highlight digital health's potential to expand access and improve long-term outcomes in cardiac care.

Emergence agitation (EA) is a common concern in maxillofacial surgeries under general anaesthesia. Therefore, it is of interest to evaluate the role of intraoperative dexmedetomidine infusion in its prevention. Ninety ASA I-II adult patients were randomized into two groups general anaesthesia alone (Group A) and general anaesthesia with dexmedetomidine (Group B). Dexmedetomidine significantly reduced the incidence and severity of EA (p

Halophytes are remarkable plants that have evolved unique strategies to thrive in saline environments. Microbial communities of halophytes are being studied extensively as potential sources of bioactive compounds. Therefore, it is of interest to identify the secondary metabolites of the rhizospheric bacterial Desertihabitans sp. FB5 from the halophyte Salsola Imbricata. Strain Desertihabitans sp. FB5 was identified using a molecular technique (16S rDNA) and showed a similarity of 99% to Desertihabitans aurantiacus CPCC 204711T. Antifungal activity of the strain was tested against five different pathogenic fungi: Fusarium moniliforme, Altenaria mali, Magnaporthe grisea, Phytophthora capsici and Pythium ultimum in an in vitro assay. Desertihabitans sp. FB5 showed weak-to-moderate inhibition of different pathogenic fungi tested in the inhibitory assay. The production of lytic enzymes was evaluated using different enzymatic activities. Desertihabitans sp. FB5 was positive for both cellulolytic and lipolytic activities. To detect bioactive metabolites, gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) were performed. Both analyses showed the presence of the antimicrobial compound bacitracin and phytohormones, Indole-3-acetic acid (IAA) and Gibberellin A3 (GA3) in the culture extracts of strain. Our results demonstrated that halophytes are recognised as key source of potent bacterial strains capable of producing metabolites of industrial and medical significance.

The biomechanical function of teeth with endodontic treatment is directly impacted by the restorative material chosen. It has been demonstrated that biomimetic restorative techniques, such as fiber-reinforced composites, polyethylene fibre reinforcement, and bioactive core materials, more successfully mimic the functional characteristics of natural dentin and enamel than traditional composites. Therefore, it is of interest to evaluate the strengthening effect of biomimetic restorative materials on root canal-treated teeth subjected to orthodontic intrusion and extrusion. Forty extracted maxillary premolars were restored using short fibre-reinforced composite, polyethylene fibre with composite, biodentine, or conventional composite, and tested under 150 g orthodontic force. Teeth restored with fibre-based materials exhibited significantly higher fracture resistance than biodentine and control groups (p < 0.05). Favorable fracture patterns predominated in fibre-reinforced groups, while conventional composites showed mainly unfavorable fractures. Biomimetic restorations, particularly fibre-based materials, enhance fracture resistance and promote favorable failure modes during orthodontic loading.