Pub Date : 2017-07-20DOI: 10.15406/ICPJL.2017.05.00118
A. Silva, D. Silva, J. I. Santos, G. Le, R. D. Sousa, Ruan Carlos Gomes da Silva, Josefa Elaine Silva Germinio, S. R. Oliveira
Upper airway infections are one of the most common causes of medical appointment in clinical practice mainly faced by pediatric population.1 According to a study conducted by Morais et al.2 the incidence of respiratory tract infections due to β-hemolytic streptococcus can be more than 18times higher in children attending some day care center or environments where they are close to others sharing belongings. However, individuals of all ages are susceptible to propagation of this microorganism under conditions of overcrowding, because the interpersonal dissemination of these bacteria occurs through aerosolized microdroplets and/or by direct contact, mainly in environments where there are clusters of people. Among the diseases that affect the upper airways, acute pharyngitis (AP) is one of the most frequent in children. Although most of the AP is of viral origin, Group a Streptococcus Beta-hemolytic (EBHGA) presents as a significant bacterial etiological agent diagnosed in about 15-30% of acute pharyngitis.3 EBHGA or Streptococcus pyogenic is grampositive aerobic bacteria that causes a variety of infectious syndromes4 and is considered of great clinical interest due to its high pathogen city, usually involving or pharynx and skin, as a consequence these bacteria may cause several inflammatory diseases. One of the main laboratorial characteristics this pathogen presents to be identified and classified is the ability to shatter completely red blood cells in 5% sheep blood culture, causing a transparency in the culture medium, which is called Beta-hemolytic.5 Streptococcus pyogenic is important when compared to groups B, C and G, not only because it is the main etiological agent of streptococcal pharyngitis,6 but also because it causes suppurate complications such as, cervical adenitis, peritonsillar abscess, retropharyngeal or cervical abscess.7 In addition, EBHGA is related to other diseases such as streptococcal toxic shock syndrome, necrotizing fasciitis, scarlet fever and skin infections.8 According to Areas et al.9 its main complications are acute rheumatic fever, rheumatic heart disease and acute streptococcal disease, with a higher incidence especially in developing countries. Therefore, the early diagnosis of this condition, followed by adequate antimicrobial treatment, is extremely important not just for the prevention of rheumatic fever (RF) and other pathologies, but also for the reduction of EBHGA transmission among patients.3 Living in restricted settings, such as day care centers and schools, can greatly influence the dissemination of these bacteria, placing the health of children and adolescents at risk,10 considering that children and teenagers or pharynx is very sensitive to EBHGA infections, especially among 5 And 15years of age.11 Besides that, they can carry pathogenic microorganisms without presenting symptoms, characterizing the asymptomatic carriers. The epidemiological profile of this pathogen shows the relevance of it’s diagno
{"title":"Prevalence of streptocochemical hemolytic beta from group a in asympletic children","authors":"A. Silva, D. Silva, J. I. Santos, G. Le, R. D. Sousa, Ruan Carlos Gomes da Silva, Josefa Elaine Silva Germinio, S. R. Oliveira","doi":"10.15406/ICPJL.2017.05.00118","DOIUrl":"https://doi.org/10.15406/ICPJL.2017.05.00118","url":null,"abstract":"Upper airway infections are one of the most common causes of medical appointment in clinical practice mainly faced by pediatric population.1 According to a study conducted by Morais et al.2 the incidence of respiratory tract infections due to β-hemolytic streptococcus can be more than 18times higher in children attending some day care center or environments where they are close to others sharing belongings. However, individuals of all ages are susceptible to propagation of this microorganism under conditions of overcrowding, because the interpersonal dissemination of these bacteria occurs through aerosolized microdroplets and/or by direct contact, mainly in environments where there are clusters of people. Among the diseases that affect the upper airways, acute pharyngitis (AP) is one of the most frequent in children. Although most of the AP is of viral origin, Group a Streptococcus Beta-hemolytic (EBHGA) presents as a significant bacterial etiological agent diagnosed in about 15-30% of acute pharyngitis.3 EBHGA or Streptococcus pyogenic is grampositive aerobic bacteria that causes a variety of infectious syndromes4 and is considered of great clinical interest due to its high pathogen city, usually involving or pharynx and skin, as a consequence these bacteria may cause several inflammatory diseases. One of the main laboratorial characteristics this pathogen presents to be identified and classified is the ability to shatter completely red blood cells in 5% sheep blood culture, causing a transparency in the culture medium, which is called Beta-hemolytic.5 Streptococcus pyogenic is important when compared to groups B, C and G, not only because it is the main etiological agent of streptococcal pharyngitis,6 but also because it causes suppurate complications such as, cervical adenitis, peritonsillar abscess, retropharyngeal or cervical abscess.7 In addition, EBHGA is related to other diseases such as streptococcal toxic shock syndrome, necrotizing fasciitis, scarlet fever and skin infections.8 According to Areas et al.9 its main complications are acute rheumatic fever, rheumatic heart disease and acute streptococcal disease, with a higher incidence especially in developing countries. Therefore, the early diagnosis of this condition, followed by adequate antimicrobial treatment, is extremely important not just for the prevention of rheumatic fever (RF) and other pathologies, but also for the reduction of EBHGA transmission among patients.3 Living in restricted settings, such as day care centers and schools, can greatly influence the dissemination of these bacteria, placing the health of children and adolescents at risk,10 considering that children and teenagers or pharynx is very sensitive to EBHGA infections, especially among 5 And 15years of age.11 Besides that, they can carry pathogenic microorganisms without presenting symptoms, characterizing the asymptomatic carriers. The epidemiological profile of this pathogen shows the relevance of it’s diagno","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":"5 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43878267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-20DOI: 10.15406/ICPJL.2017.04.00114
Judith Namuyonga, Twalib Olega, E. Tenywa, Sulaiman Lubega, R. Idro, H. Heather, P. Lwabi
Tetralogy of Fallot is the most common cyanotic congenital heart disease worldwide [1]. Among other conotruncal abnormalities, 13-16% of Tetralogy of Fallot individuals are reported to have 22q11.2 deletion syndrome which is characterized by thymic hypoplasia, endocrine abnormalities and hypocalcaemia [2]. Individuals with micro deletion 22q11.2 deletion syndrome are prone to auto immune disorders. Defects in thymic development predispose them to impaired immune function especially T cell deficiency [3]. However autoimmune vasculitis has not been well documented in children with Tetralogy of Fallot. We report on an eleven-year-old child post Tetralogy of Fallot repair who presented with persistent fevers and an over whelming infection.
{"title":"Autoimmune vasculitis in a child following tetralogy of Fallot repair in Uganda","authors":"Judith Namuyonga, Twalib Olega, E. Tenywa, Sulaiman Lubega, R. Idro, H. Heather, P. Lwabi","doi":"10.15406/ICPJL.2017.04.00114","DOIUrl":"https://doi.org/10.15406/ICPJL.2017.04.00114","url":null,"abstract":"Tetralogy of Fallot is the most common cyanotic congenital heart disease worldwide [1]. Among other conotruncal abnormalities, 13-16% of Tetralogy of Fallot individuals are reported to have 22q11.2 deletion syndrome which is characterized by thymic hypoplasia, endocrine abnormalities and hypocalcaemia [2]. Individuals with micro deletion 22q11.2 deletion syndrome are prone to auto immune disorders. Defects in thymic development predispose them to impaired immune function especially T cell deficiency [3]. However autoimmune vasculitis has not been well documented in children with Tetralogy of Fallot. We report on an eleven-year-old child post Tetralogy of Fallot repair who presented with persistent fevers and an over whelming infection.","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":"4 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41792944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-16DOI: 10.15406/ICPJL.2017.04.00113
G. Gogoi, M. Borgohain, Projnan Saikia, Brinkal Patel, R. Hazarika, RC Brahma, B. Gogoi, N. Saikia, Jolly Rabha
1Assistant Professor of Pathology, Assam Medical College, India 2,3,5Professor of Pathology, Assam Medical College, India 4Graduate Trainee of Pathology, Assam Medical College, India 6Associate Professor of Surgery, Assam Medical College, India 7Demonstrator of Pathology, Assam Medical College, India 8Associate Professor of Otolaryngology, Assam Medical College, India 9Assistant Professor, Pediatrics, Assam Medical College, India
{"title":"Histomorphological study of soft tissue tumors and review of literature of rarer types","authors":"G. Gogoi, M. Borgohain, Projnan Saikia, Brinkal Patel, R. Hazarika, RC Brahma, B. Gogoi, N. Saikia, Jolly Rabha","doi":"10.15406/ICPJL.2017.04.00113","DOIUrl":"https://doi.org/10.15406/ICPJL.2017.04.00113","url":null,"abstract":"1Assistant Professor of Pathology, Assam Medical College, India 2,3,5Professor of Pathology, Assam Medical College, India 4Graduate Trainee of Pathology, Assam Medical College, India 6Associate Professor of Surgery, Assam Medical College, India 7Demonstrator of Pathology, Assam Medical College, India 8Associate Professor of Otolaryngology, Assam Medical College, India 9Assistant Professor, Pediatrics, Assam Medical College, India","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":"4 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2017-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45569002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-15DOI: 10.15406/icpjl.2017.04.00112
F. Khan, R. Zafar, M. F. Lambert, Yasmine Kanaan, T. Naab
Ductal and lobular breast neoplasms represent morphologically distinct entities. Ductal breast carcinoma may involve lobules and lobular carcinoma may involve ducts. Invasive lobular carcinoma is difficult to diagnose on screening mammogram since it often does not form a mass lesion in contrast to ductal breast cancer [13]. It may present as an area of thickening or change in texture [4]. Lobular neoplasia includes atypical lobular hyperplasia, lobular carcinoma in situ (LCIS) and invasive lobular carcinoma.
{"title":"Aggressive well differentiated invasive ductal carcinoma twelve years after bilateral mastectomies for invasive lobular carcinoma","authors":"F. Khan, R. Zafar, M. F. Lambert, Yasmine Kanaan, T. Naab","doi":"10.15406/icpjl.2017.04.00112","DOIUrl":"https://doi.org/10.15406/icpjl.2017.04.00112","url":null,"abstract":"Ductal and lobular breast neoplasms represent morphologically distinct entities. Ductal breast carcinoma may involve lobules and lobular carcinoma may involve ducts. Invasive lobular carcinoma is difficult to diagnose on screening mammogram since it often does not form a mass lesion in contrast to ductal breast cancer [13]. It may present as an area of thickening or change in texture [4]. Lobular neoplasia includes atypical lobular hyperplasia, lobular carcinoma in situ (LCIS) and invasive lobular carcinoma.","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49429088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-08DOI: 10.15406/ICPJL.2017.04.00111
V. Bhatia, A. Jawarkar, Varun Gohil, Darshana Patel
The most common helminthic infection occurring worldwide is considered to be Enterobius Vermicularis commonly known as pinworm or thread worm mainly in GIT.1,2 The incidence of Enterobius Vermicularis infection is predominantly seen in children which is around 4% to 28% and is rarely seen in adults.3,4 The most common route of infection is through feco-oral route. Enterobius Vermicularis infection is generally asymptomatic, if it infects appendix it may mimic acute appendicitis without histological evidence of acute inflammation.5,6 The pathological diagnosis of Enterobius Vermicularis in appendix is an infrequent finding and is mainly associated with chronic inflammatory infiltrate & eosinophils in the mucosa without invasion of mucosa by the parasite.7 We report a case of 22year old young adult male with right iliac fossa tenderness who underwent appendicectomy and pathology revealed Enterobius Vermicularis.
{"title":"Parasitic infection mimicking acute appendicitis in an adult male-A rare case","authors":"V. Bhatia, A. Jawarkar, Varun Gohil, Darshana Patel","doi":"10.15406/ICPJL.2017.04.00111","DOIUrl":"https://doi.org/10.15406/ICPJL.2017.04.00111","url":null,"abstract":"The most common helminthic infection occurring worldwide is considered to be Enterobius Vermicularis commonly known as pinworm or thread worm mainly in GIT.1,2 The incidence of Enterobius Vermicularis infection is predominantly seen in children which is around 4% to 28% and is rarely seen in adults.3,4 The most common route of infection is through feco-oral route. Enterobius Vermicularis infection is generally asymptomatic, if it infects appendix it may mimic acute appendicitis without histological evidence of acute inflammation.5,6 The pathological diagnosis of Enterobius Vermicularis in appendix is an infrequent finding and is mainly associated with chronic inflammatory infiltrate & eosinophils in the mucosa without invasion of mucosa by the parasite.7 We report a case of 22year old young adult male with right iliac fossa tenderness who underwent appendicectomy and pathology revealed Enterobius Vermicularis.","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46046364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-01DOI: 10.15406/ICPJL.2017.4.00115
Syed A. A. Aziz
According to the work done in my lab the most significant issues is the average age at which the breast cancer effect the women of east and west, there is a clear difference of 10 years as the average age of eastern women is 50 years and western female gets at 60 years and this difference of 10 year is being carried by the migrant women in the west as well and many studies should this difference is purely genetic and not environmental. Based these studies and advocacy group the age of mammography has been reduced to 10 years for eastern origin women. Once the breast cancer has been diagnosed the next step is prognosis. Family history does play a different role in prognosis according to a contemporarily published study where an accumulated number of ER negative & PR negative breast cancer was acclaimed among younger Spanish women who have a family account of the disease [1]. The established/routinely used prognostic markers which are being used by some of the highly respected institutes are ER, PR, Her-2, p53, CD31, Ki-67/PCNA. Trastuzumab is being offered to Her-2 positive patients who will benefit with this monoclonal drug or in other words Her-2 is being performed on a selective group of patients. Whereas ER, PR, p53, CD31, Ki-67/PCNA are being performed on almost every breast cancer patient.
{"title":"Breast cancer progression, prognosis and prospective outcomes","authors":"Syed A. A. Aziz","doi":"10.15406/ICPJL.2017.4.00115","DOIUrl":"https://doi.org/10.15406/ICPJL.2017.4.00115","url":null,"abstract":"According to the work done in my lab the most significant issues is the average age at which the breast cancer effect the women of east and west, there is a clear difference of 10 years as the average age of eastern women is 50 years and western female gets at 60 years and this difference of 10 year is being carried by the migrant women in the west as well and many studies should this difference is purely genetic and not environmental. Based these studies and advocacy group the age of mammography has been reduced to 10 years for eastern origin women. Once the breast cancer has been diagnosed the next step is prognosis. Family history does play a different role in prognosis according to a contemporarily published study where an accumulated number of ER negative & PR negative breast cancer was acclaimed among younger Spanish women who have a family account of the disease [1]. The established/routinely used prognostic markers which are being used by some of the highly respected institutes are ER, PR, Her-2, p53, CD31, Ki-67/PCNA. Trastuzumab is being offered to Her-2 positive patients who will benefit with this monoclonal drug or in other words Her-2 is being performed on a selective group of patients. Whereas ER, PR, p53, CD31, Ki-67/PCNA are being performed on almost every breast cancer patient.","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49007642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-24DOI: 10.15406/ICPJL.2017.04.00110
Sohaib Abu Farsakh, H. Farsakh
{"title":"Breast carcinoma versus benign breast lesions diagnosed by fine needle aspiration and core biopsies: types, age, risk factors, and hormonal receptors status in Jordan","authors":"Sohaib Abu Farsakh, H. Farsakh","doi":"10.15406/ICPJL.2017.04.00110","DOIUrl":"https://doi.org/10.15406/ICPJL.2017.04.00110","url":null,"abstract":"","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45869642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-16DOI: 10.15406/ICPJL.2017.04.00109
S. Thind
apple scab, mango malformation, guava wilt, fire blights, banana bunchy top and wilt, brown rots of stone fruits, crown galls, downy and powdery mildews are the destructive fruit diseases causing huge losses to the fruit industry worldwide.1 Intensive agriculture provides greatest opportunities for the buildup of many new diseases and insect–pests. Plant protection mainly aims to attain maximum yield by keeping the crops healthy and preventing the losses occurring from diseases and insect–pests. The successful and profitable fruit industry largely depends on the adoption of improved scientific agricultural technology. A principle of plant disease management broadly includes preventive measures and curative measures that cure the plants suffering from diseases. But none of the control methods when applied individually provide satisfactory and effective disease control. Hence, Integrated Disease Management (IDM) is the complete solution of all the disease problems. This chapter describes the role and application of plant pathology to horticulture in managing diseases of fruit crops. The intended scientific information will be beneficial to the students, scientists, researchers, planners and extension personnel for better understanding of various plant protection methods. This better understanding will lead to boost the world fruit industry for prosperity.
{"title":"Principles of disease management in fruit crops","authors":"S. Thind","doi":"10.15406/ICPJL.2017.04.00109","DOIUrl":"https://doi.org/10.15406/ICPJL.2017.04.00109","url":null,"abstract":"apple scab, mango malformation, guava wilt, fire blights, banana bunchy top and wilt, brown rots of stone fruits, crown galls, downy and powdery mildews are the destructive fruit diseases causing huge losses to the fruit industry worldwide.1 Intensive agriculture provides greatest opportunities for the buildup of many new diseases and insect–pests. Plant protection mainly aims to attain maximum yield by keeping the crops healthy and preventing the losses occurring from diseases and insect–pests. The successful and profitable fruit industry largely depends on the adoption of improved scientific agricultural technology. A principle of plant disease management broadly includes preventive measures and curative measures that cure the plants suffering from diseases. But none of the control methods when applied individually provide satisfactory and effective disease control. Hence, Integrated Disease Management (IDM) is the complete solution of all the disease problems. This chapter describes the role and application of plant pathology to horticulture in managing diseases of fruit crops. The intended scientific information will be beneficial to the students, scientists, researchers, planners and extension personnel for better understanding of various plant protection methods. This better understanding will lead to boost the world fruit industry for prosperity.","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45895858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-11DOI: 10.15406/ICPJL.2017.04.00108
A. E. Haynes
{"title":"Saving $1 million (and counting) on blood acquisition","authors":"A. E. Haynes","doi":"10.15406/ICPJL.2017.04.00108","DOIUrl":"https://doi.org/10.15406/ICPJL.2017.04.00108","url":null,"abstract":"","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45044264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-08DOI: 10.15406/ICPJL.2017.04.00107
D. Paul, Abu Naser Ibne Sattar, A. Roy, S. Islam, Sheuly Ferdousi, T. Paul, Mesbah U. Ahmed, S. Sikder
Results: We found high percentage of expression of CD64 on neutrophils in patients (67.73 ± 24.74) when compared with controls (8.19 ± 3.64) and also their percentage of expression was higher in culture positive sepsis (76.25 ± 29.07) than culture negative sepsis (42.21 ± 33.24). In the present study, I/T ratio >0.2 had a sensitivity, specificity, PPV, NPV and accuracy i.e. 70.0%, 72.0%, 33.3%, 92.3% and 71.7% respectively.
{"title":"Role of neutrophil CD64 as an emerging biomarker in the evaluation of neonatal sepsis","authors":"D. Paul, Abu Naser Ibne Sattar, A. Roy, S. Islam, Sheuly Ferdousi, T. Paul, Mesbah U. Ahmed, S. Sikder","doi":"10.15406/ICPJL.2017.04.00107","DOIUrl":"https://doi.org/10.15406/ICPJL.2017.04.00107","url":null,"abstract":"Results: We found high percentage of expression of CD64 on neutrophils in patients (67.73 ± 24.74) when compared with controls (8.19 ± 3.64) and also their percentage of expression was higher in culture positive sepsis (76.25 ± 29.07) than culture negative sepsis (42.21 ± 33.24). In the present study, I/T ratio >0.2 had a sensitivity, specificity, PPV, NPV and accuracy i.e. 70.0%, 72.0%, 33.3%, 92.3% and 71.7% respectively.","PeriodicalId":92215,"journal":{"name":"International clinical pathology journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42334700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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