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Morphology-dependent catalytic performance of Co3O4 nanomaterials in the oxidative dehydrogenation of tetrahydroquinolines 纳米材料Co3O4在四氢喹啉氧化脱氢反应中的催化性能
IF 6.7 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-30 DOI: 10.1039/d5nr04947d
Suresh Babu Putla, Palanivel Subha, Nittan Singh, Putla Sudarsanam, PAVULURI Srinivasu
Nanostructured metal oxides with controlled particle morphology are considered to be highly effective for heterogeneous catalysis owing to their unique surface, acid-base, and redox properties. Here, we report the synthesis of shape-controlled Co3O4 nanocatalysts for the oxidative dehydrogenation of N-heterocycles to their corresponding aromatic derivatives. Various Co3O4 nanostructured catalysts, namely spherical-like (Co3O4-SP) and cubes (Co3O4-C), along with randomly shaped nanoparticles (Co3O4-NP), were prepared via template-free hydrothermal methods and thoroughly characterized using several analytical techniques. Among them, the Co3O4-SP material exhibited superior catalytic performance in the oxidative dehydrogenation of 1,2,3,4-tetrahydroquinoline (THQ), achieving 95% conversion of THQ with 100% selectivity to quinoline, which is due to the optimum amount of Co3+ species (Co3+/Co2+ = 0.515) and acid sites (0.192 mmol g⁻¹), along with the oxygen vacancy sites. In contrast, the Co3O4-NP and Co3O4-C catalysts gave 72% and 51% conversions of THQ, respectively, although 100% quinoline selectivity was achieved in both cases. The substrate scope was further extended to diverse N-heteroaromatic compounds (10 examples), delivering good to excellent yields under mild reaction conditions. Notably, the Co3O4-SP catalyst exhibited excellent reusability, with negligible loss in its catalytic activity over five cycles. The evaluated green chemistry metrics further demonstrated the sustainability of the developed Co3O4-SP-catalyzed oxidative dehydrogenation of N-heterocycles.
具有可控颗粒形态的纳米结构金属氧化物由于其独特的表面、酸碱和氧化还原性质,被认为对多相催化非常有效。在这里,我们报道了形状控制的Co3O4纳米催化剂的合成,用于n -杂环氧化脱氢成相应的芳香衍生物。采用无模板水热法制备了球形(Co3O4- sp)、立方体(Co3O4- c)以及随机形状的纳米颗粒(Co3O4- np)等多种Co3O4纳米结构催化剂,并利用多种分析技术对其进行了全面表征。其中,Co3O4-SP材料在1,2,3,4-四氢喹啉(THQ)的氧化脱氢反应中表现出优异的催化性能,由于Co3+的量(Co3+/Co2+ = 0.515)和酸位(0.192 mmol g⁻¹)以及氧空位的数量最优,THQ的转化率为95%,选择性为100%。相比之下,Co3O4-NP和Co3O4-C催化剂的THQ转化率分别为72%和51%,尽管这两种催化剂的喹啉选择性都达到了100%。底物范围进一步扩展到不同的n -杂芳烃化合物(10个例子),在温和的反应条件下获得了良好的收率。值得注意的是,Co3O4-SP催化剂具有良好的可重复使用性,在5个循环中其催化活性的损失可以忽略不计。评价的绿色化学指标进一步证明了所开发的co3o4 - sp催化n -杂环氧化脱氢的可持续性。
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引用次数: 0
A meniscus morphology modulation method for meniscus-confined electrodeposition. 半月板受限电沉积的半月板形态调制方法。
IF 6.7 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-30 DOI: 10.1039/d5nr04452a
Yi Zhou,Xiaobo Liao,Long Chen,Xuan Liao,Jian Zhuang,Lei Cheng,Wang Zhi Wu,Jia Xin Yu,Yinghao Wang,Linxiao Teng
Meniscus-confined electrodeposition (MCED) is an emerging micro-nano-fabrication method. It has attracted much attention due to its low cost, simple process and ability to freely fabricate complex three-dimensional structures with high aspect ratios. However, in the MCED process, the meniscus morphology (confined electrochemical reaction micro-region) is susceptible to the interference of external factors (environmental humidity and variation in the distance between the probe tip and the deposited microstructure), thereby affecting the deposition continuity and stability. To address this challenge, we developed a meniscus morphology regulation method that controls the pressure inside glass probes through tail-end pressurization to adjust the radius of meniscus profile. Simulation and experimental results show that by adjusting the solution pressure (ranging from -5 kPa to 5 kPa), the meniscus width can be controlled within 0.6 to 1.5 times its initial value (the width under no applied pressure). The most notable achievement is that a copper pillar array with a height of 33 μm and a width ranging from 7 to 15 μm is successfully fabricated by adjusting the diameter of the meniscus profile during the deposition process. The results show that the proposed method not only improves the continuity and stability of electrochemical deposition, but also provides a new idea for the preparation of complex three-dimensional structures, which effectively expands the application scenarios of MCED.
半月板约束电沉积(MCED)是一种新兴的微纳米加工方法。它以其成本低、工艺简单、能够自由制作高纵横比的复杂三维结构而备受关注。然而,在MCED过程中,半月板形貌(受限电化学反应微区)容易受到外界因素(环境湿度、探针尖端与沉积微观结构之间距离的变化)的干扰,从而影响沉积的连续性和稳定性。为了解决这一挑战,我们开发了一种半月板形态调节方法,通过尾端加压来控制玻璃探头内的压力,以调节半月板轮廓的半径。仿真和实验结果表明,通过调节溶液压力(-5 kPa ~ 5 kPa),可以将半月板宽度控制在初始值(无压力下宽度)的0.6 ~ 1.5倍。最显著的成果是在沉积过程中通过调整半月板轮廓的直径,成功地制备了高33 μm、宽7 ~ 15 μm的铜柱阵列。结果表明,该方法不仅提高了电化学沉积的连续性和稳定性,而且为复杂三维结构的制备提供了新的思路,有效地拓展了MCED的应用场景。
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引用次数: 0
The role of lattice strain in advancing electrocatalytic performance: from mechanisms to practical applications. 晶格应变在提高电催化性能中的作用:从机理到实际应用。
IF 5.1 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-30 DOI: 10.1039/d5nr04443j
Juan Luo, Jiaxin Tong, Haili Zhao, Xiaonian Zeng, Feng Liu, Haiyan Wu, Hao Cui, Pengfei Tan, Jun Pan

Lattice strain engineering has emerged as a powerful and versatile strategy for modulating the electronic and geometric structures of electrocatalysts at the atomic scale. By finely tuning interatomic distances and orbital interactions, lattice strain directly influences adsorption energetics and reaction kinetics, offering an effective pathway to overcome intrinsic activity and stability limitations in key electrochemical processes. This review systematically summarizes the fundamental principles of lattice strain effects, including electronic and geometric modulation mechanisms and their correlation with the d-band center theory. We highlight the main approaches for strain induction, such as orbital symmetry matching, antibonding state occupancy, charge redistribution, and adsorbate-induced surface relaxation. We further summarize quantitative relationships between strain and catalytic activity, including volcano plots, strain-ΔG* correlations, and strain-TOF dependencies, distinguishing between compressive and tensile strain effects across various reactions such as HER, OER, ORR, CO2RR, and NRR. Special attention is given to how controlled strain optimizes intermediate adsorption energies in accordance with the Sabatier principle, thereby enhancing catalytic activity, selectivity, and durability. Finally, we discuss the remaining challenges in controlling strain magnitude, stability, and scalability, and outline perspectives for integrating strain engineering with other design principles. This review establishes lattice strain as a unifying and predictive framework for rational catalyst design, paving the way for high-performance electrocatalysts in sustainable energy conversion and storage technologies.

晶格应变工程已经成为在原子尺度上调制电催化剂的电子和几何结构的一种强大而通用的策略。通过微调原子间距离和轨道相互作用,晶格应变直接影响吸附能量和反应动力学,为克服关键电化学过程的固有活性和稳定性限制提供了有效途径。本文系统地总结了晶格应变效应的基本原理,包括电子调制机制和几何调制机制以及它们与d波段中心理论的关系。我们重点介绍了应变诱导的主要方法,如轨道对称匹配、反键态占用、电荷重分配和吸附诱导的表面弛豫。我们进一步总结了应变和催化活性之间的定量关系,包括火山图,应变-ΔG*相关性和应变- tof依赖性,区分了各种反应(如HER, OER, ORR, CO2RR和NRR)中的压缩和拉伸应变效应。特别注意控制菌株如何根据萨巴蒂尔原理优化中间吸附能,从而提高催化活性、选择性和耐久性。最后,我们讨论了控制应变大小、稳定性和可扩展性方面的挑战,并概述了将应变工程与其他设计原则相结合的观点。本文建立了晶格应变作为合理设计催化剂的统一和预测框架,为可持续能量转换和存储技术中的高性能电催化剂铺平了道路。
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引用次数: 0
Nanoindentation-induced subsurface phase engineering in oxide-capped silicon. 氧化盖硅纳米压痕诱导的亚表面相工程。
IF 6.7 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-30 DOI: 10.1039/d5nr04069h
Megha Sasidharan Nisha,Kiran Mangalampalli
The controlled formation of high-pressure silicon polymorphs beneath an oxide layer offers a new paradigm for subsurface phase engineering. We systematically compared sharp Berkovich and spherical nanoindentation on 285 nm SiO2-capped Si(100) using Raman spectroscopy and cross-sectional electron microscopy to reveal how contact geometry and oxide constraint govern phase transformation. Sharp indentation initiates R8 (rhombohedral)/BC8 (body-centered-cubic) phase formation at low loads (42 mN), but the high stress concentration promotes early oxide fracture and radial cracking, limiting the continuous crystalline volume. In contrast, spherical indentation delays observable transformation until ∼92 mN, distributing stress more uniformly. Crucially, we identify a "critical loading window" for optimization. While moderate spherical loads (∼200 mN) facilitate highly ordered crystalline recovery with intact interfaces, excessive loads (∼500 mN) exceed the oxide's confinement capacity, favoring collapse into a disordered amorphous state and localized fracture due to the significant volumetric expansion of the intermediate β-Sn phase. Our results confirm that the oxide modulates stress-relaxation kinetics without altering the fundamental 11-12 GPa transformation threshold. These findings explicitly define the operational limits for dielectric confinement, providing a versatile pathway for engineering subsurface crystalline phases with enhanced carrier mobility and sub-bandgap optical absorption for next-generation silicon photonic and sensing platforms.
氧化层下高压硅多晶的可控形成为地下相工程提供了新的范例。我们使用拉曼光谱和横截面电子显微镜系统地比较了285 nm二氧化硅覆盖的Si(100)上的尖锐Berkovich和球形纳米压痕,以揭示接触几何形状和氧化物约束如何影响相变。在低载荷(42 mN)下,尖锐的压痕会形成R8(菱形体)/BC8(体心立方)相,但高应力浓度会促进早期氧化物断裂和径向开裂,限制了连续结晶体积。相比之下,球形压痕将可观察到的转变延迟到~ 92 mN,使应力分布更均匀。至关重要的是,我们确定了一个“关键加载窗口”进行优化。虽然适度的球形载荷(~ 200 mN)有利于高度有序的晶体恢复和完整的界面,但过量的载荷(~ 500 mN)超过了氧化物的约束能力,有利于崩溃成无序的非晶态和局部断裂,因为中间β-Sn相的显著体积膨胀。我们的研究结果证实,氧化物在不改变基本的11-12 GPa转变阈值的情况下调节应力松弛动力学。这些发现明确地定义了介电约束的操作极限,为下一代硅光子和传感平台提供了一种具有增强载流子迁移率和亚带隙光吸收的工程亚表面晶体相的通用途径。
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引用次数: 0
Recent advances in femtosecond laser micro/nano processing of perovskite for optical applications 飞秒激光微纳加工光学用钙钛矿的研究进展
IF 6.7 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-30 DOI: 10.1039/d5nr04944j
Hao Song, Kai Yin, Jianqiang Xiao, Jiaqing Pei, Fan Zhang, Yu Chen
In recent years, with the rapid development of new energy and optoelectronic technologies, perovskite materials have become a research hotspot of common interest in both academic and industrial communities due to their excellent optoelectronic properties, low-cost fabrication processes, and diverse application scenarios. However, achieving efficient and high-precision processing of perovskite materials remains a key challenge hindering their broader application. In this context, femtosecond laser processing technology, leveraging its ultra-short pulse duration and high-precision machining capabilities, has opened up new possibilities for the research and application of perovskite materials. This review summarizes the mechanisms and recent advances in femtosecond laser micro/nano-processing of perovskite single crystals, glasses, and polymer thin films, systematically outlines relevant methods and their unique advantages, provides an in-depth discussion on the application potential of femtosecond laser direct writing in the field of perovskite luminescence, and offers prospects for future optimization and improvement of femtosecond laser-based preparation and processing techniques. The findings presented are expected to provide important theoretical support and technical reference for further research and practical applications of perovskite materials.
近年来,随着新能源和光电子技术的快速发展,钙钛矿材料以其优异的光电性能、低成本的制造工艺和多样化的应用场景,成为学术界和工业界共同关注的研究热点。然而,实现钙钛矿材料的高效和高精度加工仍然是阻碍其广泛应用的关键挑战。在此背景下,飞秒激光加工技术凭借其超短脉冲持续时间和高精度加工能力,为钙钛矿材料的研究和应用开辟了新的可能性。本文综述了飞秒激光微纳加工钙钛矿单晶、玻璃和聚合物薄膜的机理和最新进展,系统概述了相关方法及其独特优势,深入探讨了飞秒激光直写技术在钙钛矿发光领域的应用潜力,并对飞秒激光制备和加工技术的未来优化和改进进行了展望。研究结果有望为钙钛矿材料的进一步研究和实际应用提供重要的理论支持和技术参考。
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引用次数: 0
Single-Element Heterovalent Doping Strategy Stabilizing the Cathode Structure for Reversible Zinc-Ion Storage to Power Soft Robotics 稳定可逆锌离子存储阴极结构的单元素杂价掺杂策略为软机器人供电
IF 6.7 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-29 DOI: 10.1039/d5nr04570c
Yameng Zhu, Xiaona Wang, Jiajia Xia, Xuechun Wang, Ying Kong, Yurong Zhou, Shuxuan Qu, Wei Feng, Jiangtao Di
Zinc-ion batteries (ZIBs), recognized for their safe aqueous electrolyte and low-cost, abundant zinc resources, offer significant promise for applications in energy storage. MnO2 is a promising cathode material due to its environmental friendliness and low cost, but it faces challenges related to low conductivity and structural instability. Herein, a single-element (Ce) heterovalent doping strategy was proposed to boost the capacity and structural stability of δ-MnO2 (Ce-MnO2). Ce4+ can preferentially occupy the Mn sites with the same and stable valence state to Mn4+, effectively suppress structural collapse during charge and discharge processes. Ce3+ could contribute to improved electronic conductivity through aliovalent substitution leading to charge compensation and altered the local chemical environment by creating oxygen vacancies and optimizing Mn-O interactions. Moreover, it can improve the specific surface area and provide active sites, thereby promoting electrochemical activity and facilitating superior ion transport. Consequently, The Ce-MnO2 cathode achieved a high specific capacity of 374.5 mAh g−1, with 90% capacity retention after 1000 cycles. When further applied in powering a PNIPAM hydrogel actuator, Zn//MnO2 ion batteries exhibited potential for actuator-driven technologies.
锌离子电池(zib)以其安全的水电解质和低成本、丰富的锌资源而闻名,在储能领域的应用前景广阔。二氧化锰具有环境友好、成本低等优点,是一种极具发展前景的正极材料,但其电导率低、结构不稳定等问题仍面临挑战。本文提出了单元素(Ce)杂价掺杂策略来提高δ-MnO2 (Ce- mno2)的容量和结构稳定性。Ce4+能优先占据与Mn4+价态相同且稳定的Mn位,有效抑制充放电过程中的结构坍塌。Ce3+可以通过价取代导致电荷补偿来改善电子导电性,并通过创造氧空位和优化Mn-O相互作用来改变局部化学环境。此外,它可以提高比表面积,提供活性位点,从而提高电化学活性,促进优越的离子运输。因此,Ce-MnO2阴极获得了374.5 mAh g−1的高比容量,在1000次循环后保持了90%的容量。当进一步应用于PNIPAM水凝胶致动器时,Zn//MnO2离子电池显示出致动器驱动技术的潜力。
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引用次数: 0
Interplay of Hot Carrier Relaxation and Trapping in Red Emissive Formamidinium Lead Iodide Perovskite Nanorods 红发射甲醛碘化铅钙钛矿纳米棒中热载流子弛豫和俘获的相互作用
IF 6.7 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-29 DOI: 10.1039/d5nr04239a
Ankit Kumar, P. Kumar Singha, Aakash Gupta, Tapas Pal, Sounak Bhattacharya, Anindya Datta
Stable, red-emissive formamidinium lead triiodide (FAPbI 3 ) nanorods have been synthesized by modification of conditions for the synthesis of FAPbI 3 nanocubes. The bimodal PL decays with components of 9 ns and 30 ns are ascribed to trap-assisted radiative recombination. Transient absorption spectroscopy at different pump wavelengths and fluences indicates the involvement of phonon bottleneck effect in hot carrier relaxation. Global analysis of transient absorption data yields four components. The two fastest ones (0.5-3.7 ps) are ascribed to two different hot carrier cooling pathways. The tens of picosecond component is attributed to ground state bleach associated with band-edge transition. The longest component (>1 ns, negative signal corresponding to stimulated emission, Stokes shifted with respect to the band gap) is attributed to radiative recombination involving mid-gap trap states. Hence, a detailed understanding of the interplay of hot carrier cooling and trapping in the exciton dynamics, leading to the population of radiative trap states, is obtained.
通过改进fapbi3纳米立方的合成条件,合成了稳定的红发射型三碘化甲醛铅(fapbi3)纳米棒。双峰PL衰减的分量分别为9ns和30ns,是由阱辅助的辐射复合引起的。不同泵浦波长和不同影响下的瞬态吸收光谱表明,声子瓶颈效应参与了热载子弛豫。瞬态吸收数据的全局分析产生了四个组成部分。两个最快的(0.5-3.7 ps)归因于两种不同的热载流子冷却途径。数十皮秒分量归因于与带边跃迁相关的基态漂白。最长的分量(> 1ns,对应于受激发射的负信号,相对于带隙的斯托克斯位移)归因于涉及中隙阱态的辐射复合。因此,详细了解了热载子冷却和捕获在激子动力学中的相互作用,从而导致辐射捕获态的分布。
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引用次数: 0
Recent Advances in Perovskite-Derived Microwave Absorption Materials 钙钛矿衍生微波吸收材料的研究进展
IF 6.7 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-29 DOI: 10.1039/d5nr04884b
Yu-Kai Luo, Ming Wang
The growing concern over electromagnetic pollution necessitates the developing of high-performance microwave absorption materials. Perovskites have emerged as promising candidates due to their unique crystal structure and tunable electromagnetic properties. This comprehensive review systematically elucidates the crystallographic characteristics, functional properties, and structural classifications of perovskite materials, and summarizes recent advances in perovskite-based microwave absorbers over the past decade. Critical analysis are including synthesis methodologies, performance optimization strategies with a focus on defect engineering, hetero-structure design, and multi-component hybridization, and microwave absorption enhancement. Current challenges are critically assessed, including limited high-frequency absorption (8-18 GHz) and scalability issues associated with complex perovskite structures. Finally, perspectives are discussed for the design of next-generation perovskite-derived microwave absorption materials.
随着人们对电磁污染问题的日益关注,开发高性能的微波吸收材料势在必行。钙钛矿由于其独特的晶体结构和可调谐的电磁特性而成为有希望的候选者。本文系统地阐述了钙钛矿材料的晶体学特征、功能特性和结构分类,并总结了近十年来钙钛矿基微波吸收剂的最新进展。关键分析包括合成方法、以缺陷工程为重点的性能优化策略、异质结构设计、多组分杂交和微波吸收增强。目前面临的挑战是严格评估,包括有限的高频吸收(8-18 GHz)和复杂钙钛矿结构相关的可扩展性问题。最后,对下一代钙钛矿衍生微波吸收材料的设计进行了展望。
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引用次数: 0
Nano-engineered PEDOT(MXene)/PVDF(HFP) bilayer membranes for dual-mode flexible sensing and machine learning-guided signal recognition 用于双模柔性传感和机器学习引导信号识别的纳米工程PEDOT(MXene)/PVDF(HFP)双层膜
IF 6.7 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-29 DOI: 10.1039/d5nr04473a
Pingping Wu, Lin Li, Qilin Guo, Sijing Zhang, Yuanzhen Zhou
Flexible nanostructured sensors that combine electrical conductivity, mechanical robustness, and multimodal recognition capability are crucial for next-generation wearable electronics and intelligent human-machine interfaces. This study reports a dual-mode flexible sensor based on a bilayer PEDOT(MXene)-PVDF(HFP) composite membrane (denoted as PMPH), rationally designed via electrochemical polymerization and solvent-driven interface regulation. Through dual-dopant optimization and dimethyl sulfoxide-induced structural rearrangement, the PEDOT chains exhibit a transition from benzenoid to quinoid configurations, while MXene nanosheets provide a highly conductive and mechanically resilient framework. The resulting PMPH membrane displays superior conductivity, large stretchability (up to 1200%), and stable pressure and strain responses. The dual-mode flexible sensor not only distinguishes stretching and pressing behaviors but also achieves an intelligent classification accuracy of 92.13% through a machine-learning-assisted data recognition model.This study demonstrates a simple yet efficient strategy to couple conductive polymer-MXene hybrids with flexible fluoropolymers, bridging materials design and intelligent sensing toward advanced wearable devices.
柔性纳米结构传感器结合了导电性、机械稳健性和多模态识别能力,对下一代可穿戴电子产品和智能人机界面至关重要。本研究报道了一种基于双层PEDOT(MXene)-PVDF(HFP)复合膜(简称PMPH)的双模柔性传感器,通过电化学聚合和溶剂驱动的界面调节合理设计。通过双掺杂优化和二甲亚砜诱导的结构重排,PEDOT链呈现出从苯类到醌类结构的转变,而MXene纳米片提供了一个高导电性和机械弹性的框架。由此产生的PMPH膜具有优异的导电性,大拉伸性(高达1200%),稳定的压力和应变响应。双模柔性传感器不仅能够区分拉伸和挤压行为,而且通过机器学习辅助数据识别模型实现了92.13%的智能分类准确率。这项研究展示了一种简单而有效的策略,将导电聚合物- mxene杂化物与柔性含氟聚合物、桥接材料设计和智能传感耦合到先进的可穿戴设备中。
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引用次数: 0
Recent advances in the microfluidic preparation of organic nanoparticles for cancer therapy: a review. 微流控制备有机纳米颗粒用于癌症治疗的研究进展
IF 5.1 3区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-29 DOI: 10.1039/d5nr04077a
Muqarrab Ahmed, Nadia Anwar, Tingting Yu

Organic nanoparticles can play an integral role in the biomedical field by optimizing the medication process in cancer treatment. They can ensure the non-toxic and target-specific delivery of a cancer-based antigen. Compared to conventional strategies, the microfluidic approach can ensure reproducible organic nanoparticles. The microfluidic approach can ensure the utmost controllability over reaction parameters and mixing performance. In this way, scientists can secure organic nanoparticles with a narrow size distribution and mono-dispersion. The microfluidic approach offers the chance for health scientists to secure industrial-scale productivity of organic nanoparticles. This review summarizes recent advancements in microfluidics for the synthesis of organic nanoparticles with relevant specifications. We emphasize the key fundamentals and the advantages of next-generation microfluidics over conventional strategies for the preparation of organic nanoparticles. Some positive and negative prospects that can affect the structural morphology and delivery of organic nanoparticles are highlighted. The developments in cancer-based therapies and administration routes via organic nanoparticles are also discussed briefly.

有机纳米粒子通过优化癌症治疗的药物过程,在生物医学领域发挥着不可或缺的作用。它们可以确保以癌症为基础的抗原的无毒和靶向性传递。与传统方法相比,微流体方法可以确保有机纳米颗粒的可重复性。微流控方法可以确保对反应参数和混合性能的最大可控性。通过这种方式,科学家可以获得具有窄尺寸分布和单分散的有机纳米颗粒。微流体方法为健康科学家提供了确保有机纳米颗粒工业规模生产力的机会。本文综述了近年来微流控技术在有机纳米颗粒合成方面的研究进展。我们强调的关键基础和优势的新一代微流体相对于传统策略的有机纳米颗粒的制备。强调了影响有机纳米粒子结构形态和传递的一些积极和消极的前景。本文还简要讨论了基于有机纳米颗粒的癌症治疗和给药途径的发展。
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引用次数: 0
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