{"title":"Pharmacokinetics and Bioequivalence Study of Two Proton Pump Inhibitor Products","authors":"E. Taha, F. Abd-Alla","doi":"10.9734/BJPR/2016/29952","DOIUrl":"https://doi.org/10.9734/BJPR/2016/29952","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"31 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82040508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phytochemical Study, Chemicalphysical Analysis and Toxicological Testing of Stem Bark of Dalbergia monetaria L. f.","authors":"E. Melo, R. S. Ramos, S. Almeida","doi":"10.9734/bjpr/2016/20204","DOIUrl":"https://doi.org/10.9734/bjpr/2016/20204","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"1 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73184120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Gevrenova, D. Zheleva-Dimitrova, S. Ruseva, N. Denkov, S. Konstantinov, V. Lozanov, V. Mitev
Aims: In this study, we aimed at investigating the possible cytotoxic and hepatoprotective effects of crude extract, flavonoid mixture and pure flavonoids isolated from the aerial parts of Bupleurum flavum Forsk. (Apiaceae) native to Bulgaria. Methods: For the first time flavon C-glycoside vicenin-2 was isolated from B. flavum. Its structure was identified by LC-ESI/MS/MS analysis in positive ion mode. Cytotoxic effects of vicenin-2, as well as the known flavonoid narcissin and B. flavum crude extract at concentrations ranging from Original Research Article
{"title":"Cytotoxic and Hepatoprotective Effects of Bupleurum flavum Flavonoids on Hepatocellular Carcinoma HEP-G2 Cells","authors":"R. Gevrenova, D. Zheleva-Dimitrova, S. Ruseva, N. Denkov, S. Konstantinov, V. Lozanov, V. Mitev","doi":"10.9734/BJPR/2016/25785","DOIUrl":"https://doi.org/10.9734/BJPR/2016/25785","url":null,"abstract":"Aims: In this study, we aimed at investigating the possible cytotoxic and hepatoprotective effects of crude extract, flavonoid mixture and pure flavonoids isolated from the aerial parts of Bupleurum flavum Forsk. (Apiaceae) native to Bulgaria. Methods: For the first time flavon C-glycoside vicenin-2 was isolated from B. flavum. Its structure was identified by LC-ESI/MS/MS analysis in positive ion mode. Cytotoxic effects of vicenin-2, as well as the known flavonoid narcissin and B. flavum crude extract at concentrations ranging from Original Research Article","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"18 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73324390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute and Sub-chronic Oral Toxicity of Anthocleista vogelii (Cabbage Tree) Root Hydroethanolic Extract in Albino Rats","authors":"R. Sunday, O. Ilesanmi, E. Obuotor","doi":"10.9734/BJPR/2016/27018","DOIUrl":"https://doi.org/10.9734/BJPR/2016/27018","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"112 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76799286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Summary of the Advances in Ophthalmic Drug Delivery via Iontophoresis and Microneedles","authors":"D. Vettori","doi":"10.9734/bjpr/2016/30601","DOIUrl":"https://doi.org/10.9734/bjpr/2016/30601","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"74 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87085784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aml I Mekkawy, M. El-Mokhtar, S. M. El-Shanawany, Ehsan H. Ibrahim
{"title":"Silver Nanoparticles-loaded Hydrogels, A Potential Treatment for Resistant Bacterial Infection and Wound Healing: A Review","authors":"Aml I Mekkawy, M. El-Mokhtar, S. M. El-Shanawany, Ehsan H. Ibrahim","doi":"10.9734/BJPR/2016/30525","DOIUrl":"https://doi.org/10.9734/BJPR/2016/30525","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"36 1","pages":"1-19"},"PeriodicalIF":0.0,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87158748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Dubey, P. Prabhu, J. Patel, S. Hebbar, C. Shastry, R. Charyulu
{"title":"Investigation of Nano Lipid Vesicles of Lornoxicam for Targeted Drug Delivery","authors":"A. Dubey, P. Prabhu, J. Patel, S. Hebbar, C. Shastry, R. Charyulu","doi":"10.9734/bjpr/2016/25290","DOIUrl":"https://doi.org/10.9734/bjpr/2016/25290","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"24 5","pages":"1-15"},"PeriodicalIF":0.0,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91438141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ethnopharmacological Relevance : Xylopia aethiopica or Ethiopian pepper is a plant that thrives in most of the evergreen rain forests of tropical and subtropical Africa, and it is currently grown most prominently in Ghana as a crop. Almost all parts of Xylopia aethiopica possess great medicinal values in traditional medicine. In most parts of Africa, it is used in the treatment of cough, rheumatism, dysentery, malaria, uterine fibroid, boils, and wounds among others. This review summarizes published data on phytochemistry, toxicological properties, Ethnopharmacological and other uses of Xylopia aethiopica , and aims at providing an up-to-date detail that should constitute baseline information for future research on the plant. Materials and Methods: Google Scholar, Scifinder® and PubMed were the electronic databases used to search for and filter published research on Xylopia aethiopica . Results: The various parts of Xylopia aethiopica possess a wide diversity of phytochemicals. A detailed description of only a few of these phytochemicals i.e. essential oils, alkaloids and Review Article
{"title":"Ethnopharmacological Importance of Xylopia aethiopica (DUNAL) A. RICH (Annonaceae) - A Review","authors":"J. Fetse, W. Kofie, R. Adosraku","doi":"10.9734/BJPR/2016/24746","DOIUrl":"https://doi.org/10.9734/BJPR/2016/24746","url":null,"abstract":"Ethnopharmacological Relevance : Xylopia aethiopica or Ethiopian pepper is a plant that thrives in most of the evergreen rain forests of tropical and subtropical Africa, and it is currently grown most prominently in Ghana as a crop. Almost all parts of Xylopia aethiopica possess great medicinal values in traditional medicine. In most parts of Africa, it is used in the treatment of cough, rheumatism, dysentery, malaria, uterine fibroid, boils, and wounds among others. This review summarizes published data on phytochemistry, toxicological properties, Ethnopharmacological and other uses of Xylopia aethiopica , and aims at providing an up-to-date detail that should constitute baseline information for future research on the plant. Materials and Methods: Google Scholar, Scifinder® and PubMed were the electronic databases used to search for and filter published research on Xylopia aethiopica . Results: The various parts of Xylopia aethiopica possess a wide diversity of phytochemicals. A detailed description of only a few of these phytochemicals i.e. essential oils, alkaloids and Review Article","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"146 1","pages":"1-21"},"PeriodicalIF":0.0,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80566619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimisation of Alfuzosin Hydrochloride Organogels for Transdermal Delivery","authors":"D. Prasanthi, K. Jyothirmai, Lakshmi Pk","doi":"10.9734/bjpr/2016/24433","DOIUrl":"https://doi.org/10.9734/bjpr/2016/24433","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"67 1","pages":"1-16"},"PeriodicalIF":0.0,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79604974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Q. Shaqra, A. Q. A. Shaqra, Mohammad Q. Abu Shaqra
Background: Official methods for the microbiological testing of cosmetics are available; evidence is required for the suitability of procedure employed particularly while dealing with thick or viscous preparations such as gel formulations. Aim: To illustrate the inherent problems that exist in conventional methodologies used for the microbiological testing of cosmetic gels and to recommend new strategies which could yield more consistent results. Place and Duration of Study: The work was carried out at the quality control laboratories in Jordan Medical Solutions Manufacturing Company over a period of 4 months Methodology: A carbomer based hair styling gel formulation and a cell suspension of Pseudomonas aeruginosa ATCC 9027 were prepared following standard procedures. Homogeneous dispersion of the prepared microbial challenge into the gel was achieved by two approaches. The first depended on inoculating the gel preparation prior to the addition of alkali while the second relied on breaking down the gel matrix by acidification of the original gel to pH 4
{"title":"Strategies for the Microbiological Testing of Cosmetic Gels","authors":"Q. Shaqra, A. Q. A. Shaqra, Mohammad Q. Abu Shaqra","doi":"10.9734/BJPR/2016/25196","DOIUrl":"https://doi.org/10.9734/BJPR/2016/25196","url":null,"abstract":"Background: Official methods for the microbiological testing of cosmetics are available; evidence is required for the suitability of procedure employed particularly while dealing with thick or viscous preparations such as gel formulations. Aim: To illustrate the inherent problems that exist in conventional methodologies used for the microbiological testing of cosmetic gels and to recommend new strategies which could yield more consistent results. Place and Duration of Study: The work was carried out at the quality control laboratories in Jordan Medical Solutions Manufacturing Company over a period of 4 months Methodology: A carbomer based hair styling gel formulation and a cell suspension of Pseudomonas aeruginosa ATCC 9027 were prepared following standard procedures. Homogeneous dispersion of the prepared microbial challenge into the gel was achieved by two approaches. The first depended on inoculating the gel preparation prior to the addition of alkali while the second relied on breaking down the gel matrix by acidification of the original gel to pH 4","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"13 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2016-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83025333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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