Pub Date : 2019-11-20DOI: 10.3760/CMA.J.ISSN.1674-6554.2019.11.005
W. Feng, Q. Jia, Shuping Tan, Ting Yu, Jia Li, Zhiren Wang, Fude Yang, Li Tian, Yunlong Tan
Objective To explore the relationship between plasma cytokine level and cognitive function in patients with stable schizophrenia and explore the possible role of cytokine in the occurrence mechanism of cognitive impairment in them. Methods A total of 75 stable patients who met the mental disorder diagnostic criteria of DSM-IV (patient group) and 40 healthy people (control group) were included in the essay.The method of enzymelinked immunosorbent assay (ELISA) were used to detected the concentrations of plasma proinflammatory cytokines IL-1β, IL-8, TNF-α and IFN-γ as well as the anti-inflammatory cytokines IL-10 in all research objects.The MATRICS Consensus Cognitive Battery (MCCB) was used to assess the cognitive function of patients.The relationship between plasma cytokines and cognitive function of patients were analyzed when the differences of the plasma cytokines concentrations were compared between the patient group and the control group. Results (1)Compared with the control group, plasma IL-8 (2.80(2.13)pg/ml vs 0.23 (0.80)pg/ml), TNF-α (1.16(0.47)pg/ml vs 0.67(0.15)pg/ml) in the patient group showed statistically significant difference (P<0.01). (2)In the partial correlation analysis of plasma cytokines and cognitive functions in patients, TNF-α was negatively correlated with the attention/vigilance dimensions(r=-0.29, P=0.03). Conclusion Stable schizophrenia patients have some problems with cytokine level.There is a correlation between TNF-α level and attention/vigilance dimensions.What's more, cytokine level immunological abnormalities may play some role in the development of cognitive impairment occurrence in patients. Key words: Stable schizophrenia; Cytokines; Cognitive function
目的探讨稳定期精神分裂症患者血浆细胞因子水平与认知功能的关系，探讨细胞因子在其认知障碍发生机制中的可能作用。方法纳入符合DSM-IV精神障碍诊断标准的75例稳定期患者（患者组）和40例健康人（对照组）。采用酶联免疫吸附法（ELISA）检测各研究对象血浆促炎细胞因子IL-1β、IL-8、TNF-α和IFN-γ以及抗炎细胞因子IL-10的浓度。MATRICS共识认知电池（MCCB）用于评估患者的认知功能。比较患者组和对照组血浆细胞因子浓度的差异，分析血浆细胞因子与患者认知功能的关系。结果（1）患者组血浆IL-8（2.80（2.13）pg/ml vs 0.23（0.80）pgml）、TNF-α（1.16（0.47）pg/ml vs0.67（0.15）pg/ml）与对照组比较，差异有统计学意义（P<0.01），TNF-α与注意/警惕维度呈负相关（r=-0.29，P=0.03）。TNF-α水平与注意力/警惕维度之间存在相关性。此外，细胞因子水平的免疫异常可能在患者认知障碍的发展中发挥一定作用。关键词：稳定型精神分裂症；细胞因子；认知功能
{"title":"Relationship between plasma cytokine level and cognitive function in patients with stable schizophrenia","authors":"W. Feng, Q. Jia, Shuping Tan, Ting Yu, Jia Li, Zhiren Wang, Fude Yang, Li Tian, Yunlong Tan","doi":"10.3760/CMA.J.ISSN.1674-6554.2019.11.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-6554.2019.11.005","url":null,"abstract":"Objective \u0000To explore the relationship between plasma cytokine level and cognitive function in patients with stable schizophrenia and explore the possible role of cytokine in the occurrence mechanism of cognitive impairment in them. \u0000 \u0000 \u0000Methods \u0000A total of 75 stable patients who met the mental disorder diagnostic criteria of DSM-IV (patient group) and 40 healthy people (control group) were included in the essay.The method of enzymelinked immunosorbent assay (ELISA) were used to detected the concentrations of plasma proinflammatory cytokines IL-1β, IL-8, TNF-α and IFN-γ as well as the anti-inflammatory cytokines IL-10 in all research objects.The MATRICS Consensus Cognitive Battery (MCCB) was used to assess the cognitive function of patients.The relationship between plasma cytokines and cognitive function of patients were analyzed when the differences of the plasma cytokines concentrations were compared between the patient group and the control group. \u0000 \u0000 \u0000Results \u0000(1)Compared with the control group, plasma IL-8 (2.80(2.13)pg/ml vs 0.23 (0.80)pg/ml), TNF-α (1.16(0.47)pg/ml vs 0.67(0.15)pg/ml) in the patient group showed statistically significant difference (P<0.01). (2)In the partial correlation analysis of plasma cytokines and cognitive functions in patients, TNF-α was negatively correlated with the attention/vigilance dimensions(r=-0.29, P=0.03). \u0000 \u0000 \u0000Conclusion \u0000Stable schizophrenia patients have some problems with cytokine level.There is a correlation between TNF-α level and attention/vigilance dimensions.What's more, cytokine level immunological abnormalities may play some role in the development of cognitive impairment occurrence in patients. \u0000 \u0000 \u0000Key words: \u0000Stable schizophrenia; Cytokines; Cognitive function","PeriodicalId":9940,"journal":{"name":"Chinese Journal of Behavioral Medicine and Brain Science","volume":"28 1","pages":"983-987"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47024428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-20DOI: 10.3760/CMA.J.ISSN.1674-6554.2019.11.016
Ting Xue
Despite the numerous advances in cardiovasular diseasec(CVD) prevention and control during the past decades, it remains the leading cause of mortality and morbidity worldwide, which is a huge burden for global health care.Because of the high cost and side effects of the drugs, it is necessary to find novel, cost-effective and efficient inventions for CVD prevention.Unhealthy lifestyles contribute as a risk factor, such as unhealthy diet, sedentary lifestyle, tobacco, alcohol, hypertension, diabetes, dyslipidemia and psychosocial stress.To date, numerous studies have reported the benefit of meditation on health.This review discussed the effect of meditation on cardiovascular risks, including stress, blood pressure, smoking, alcohol drinking and atherosclerosis, as well as the effect on telomere.This review limited to sitting meditation alone (yoga, Qigong, and tai chi were excluded) to reduce the confounding influence of the effects of physical therapies.Overall, meditation showed possible benefits on reduction of cardiovascular risks and improved telomerase activity, although limitations on sample size, quality and methodology are included in current studies.Given its accessibility, low-cost and low-risk, meditation might serve as an adjunct to treatment and prevention of CVD.Since the limitations of current studies, further researches are needed to be established to confirm the benefit of meditation on cardiovascular disease. Key words: Meditation; Cardiovascular disease; Cardiovascular risk
{"title":"Effects of meditation on reducing the risk of cardiovascular disease","authors":"Ting Xue","doi":"10.3760/CMA.J.ISSN.1674-6554.2019.11.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-6554.2019.11.016","url":null,"abstract":"Despite the numerous advances in cardiovasular diseasec(CVD) prevention and control during the past decades, it remains the leading cause of mortality and morbidity worldwide, which is a huge burden for global health care.Because of the high cost and side effects of the drugs, it is necessary to find novel, cost-effective and efficient inventions for CVD prevention.Unhealthy lifestyles contribute as a risk factor, such as unhealthy diet, sedentary lifestyle, tobacco, alcohol, hypertension, diabetes, dyslipidemia and psychosocial stress.To date, numerous studies have reported the benefit of meditation on health.This review discussed the effect of meditation on cardiovascular risks, including stress, blood pressure, smoking, alcohol drinking and atherosclerosis, as well as the effect on telomere.This review limited to sitting meditation alone (yoga, Qigong, and tai chi were excluded) to reduce the confounding influence of the effects of physical therapies.Overall, meditation showed possible benefits on reduction of cardiovascular risks and improved telomerase activity, although limitations on sample size, quality and methodology are included in current studies.Given its accessibility, low-cost and low-risk, meditation might serve as an adjunct to treatment and prevention of CVD.Since the limitations of current studies, further researches are needed to be established to confirm the benefit of meditation on cardiovascular disease. \u0000 \u0000 \u0000Key words: \u0000Meditation; Cardiovascular disease; Cardiovascular risk","PeriodicalId":9940,"journal":{"name":"Chinese Journal of Behavioral Medicine and Brain Science","volume":"28 1","pages":"1043-1047"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46593601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-20DOI: 10.3760/CMA.J.ISSN.1674-6554.2019.11.013
Quan Gan, Dong Zhou, Ruoqin Cheng
Objective To study the related factors of postpartum posttraumatic stress disorder. Methods Perinatal posttraumatic stress disorder questionnaire-Chinese edition(PPQ-C) was used to measure the symptoms of 1 160 puerpera in maternal and child health hospital of Hubei Province.Chi-square test was used to evaluate the differences of positive and negative symptom group in living area (urban or rural), employment status (employment or unemployment), medical insurance status (with or without medical insurance), parity (primiparity or multiparity), mode of delivery (natural labor or cesarean section). Logistic regression analysis was used to discuss the influencing factors of postpartum PTSD. Results In all 1 160, there were 188 puerpera meet the positive standard postpartum PTSD(16.2%), and the average score of PPQ-C of this 188 puerpera was (25.71±6.22). Women who were unemployed(OR=0.64, 95%CI: 0.46-0.89, P=0.01), who had no medical insurance (OR=0.60, 95%CI: 0.43-0.82, P<0.01), who gave birth by cesarean section(OR=1.47, 95%CI: 1.06-2.03, P=0.02) and who had pregnancy complications (OR=1.47, 95%CI: 1.06-2.03, P=0.03) were at higher risk of postpartum PTSD. Conclusion Medical insurance status and employment status were important factors affecting postpartum PTSD.Delivery mode and pregnancy complications are important factors affecting the occurrence and development of postpartum PTSD symptoms, and abnormal results of pregnancy examination which related to pregnancy complications are important stressor for postpartum PTSD symptoms. Key words: Postpartum; Posttraumatic stress disorder; Related factors
{"title":"Analysis of related factors of postpartum post-traumatic stress disorder","authors":"Quan Gan, Dong Zhou, Ruoqin Cheng","doi":"10.3760/CMA.J.ISSN.1674-6554.2019.11.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-6554.2019.11.013","url":null,"abstract":"Objective \u0000To study the related factors of postpartum posttraumatic stress disorder. \u0000 \u0000 \u0000Methods \u0000Perinatal posttraumatic stress disorder questionnaire-Chinese edition(PPQ-C) was used to measure the symptoms of 1 160 puerpera in maternal and child health hospital of Hubei Province.Chi-square test was used to evaluate the differences of positive and negative symptom group in living area (urban or rural), employment status (employment or unemployment), medical insurance status (with or without medical insurance), parity (primiparity or multiparity), mode of delivery (natural labor or cesarean section). Logistic regression analysis was used to discuss the influencing factors of postpartum PTSD. \u0000 \u0000 \u0000Results \u0000In all 1 160, there were 188 puerpera meet the positive standard postpartum PTSD(16.2%), and the average score of PPQ-C of this 188 puerpera was (25.71±6.22). Women who were unemployed(OR=0.64, 95%CI: 0.46-0.89, P=0.01), who had no medical insurance (OR=0.60, 95%CI: 0.43-0.82, P<0.01), who gave birth by cesarean section(OR=1.47, 95%CI: 1.06-2.03, P=0.02) and who had pregnancy complications (OR=1.47, 95%CI: 1.06-2.03, P=0.03) were at higher risk of postpartum PTSD. \u0000 \u0000 \u0000Conclusion \u0000Medical insurance status and employment status were important factors affecting postpartum PTSD.Delivery mode and pregnancy complications are important factors affecting the occurrence and development of postpartum PTSD symptoms, and abnormal results of pregnancy examination which related to pregnancy complications are important stressor for postpartum PTSD symptoms. \u0000 \u0000 \u0000Key words: \u0000Postpartum; Posttraumatic stress disorder; Related factors","PeriodicalId":9940,"journal":{"name":"Chinese Journal of Behavioral Medicine and Brain Science","volume":"28 1","pages":"1025-1029"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43180003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-20DOI: 10.3760/CMA.J.ISSN.1674-6554.2019.11.010
Zhang Junrui, Wen Xu, Ren Hongxu, Qian Ming-yi, Liu Jun, Zhao Zhengzheng, Sun Xuhai
Objective To investigate the automatic implicit attitude and explicit stigma of mental illness, and the intervention effectiveness on the stigma of mental illness in college students. Methods Single category implicit association test(SC-IAT) and questionnaire survey were used to study the degree of implicit and explicit mental illness stigma among 30 college students of Peking University, and investigated the effect of two strategies, education and contact.Data were analyzed by SPSS 22.0 with t-test and variance analysis. Results The D values of SC-IAT in the three dimensions of cognitive evaluation, emotional response and behavioral tendency of college students were 0.29±0.37, 0.24±0.43, and 0.10±0.43.There was a statistically significant difference between the cognitive evaluation dimension, the emotional response dimension and 0(t=4.069, P 0.05). The correct rates of questions "Which of the following situations do you think are considered mentally unhealthy? " and "Which of the following disorders are mental illnesses" (42±13)%, (54±13)%) increased after receiving educational intervention ((49±12)%, (64±13)%), the difference was statistically significant (F=3.682, P<0.05; F=3.576, P<0.05). Conclusion College students have implicit mental illness stigma, educational and contact intervention strategies can help improve college students' understanding of relevant knowledge, and cannot improve the level of implicit stigma of college students on mental illness. Key words: Mental illness stigma; Implicit stigma; Single category implicit association test; Stigma intervention
{"title":"Intervention study on the stigma of mental illness in college students","authors":"Zhang Junrui, Wen Xu, Ren Hongxu, Qian Ming-yi, Liu Jun, Zhao Zhengzheng, Sun Xuhai","doi":"10.3760/CMA.J.ISSN.1674-6554.2019.11.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-6554.2019.11.010","url":null,"abstract":"Objective \u0000To investigate the automatic implicit attitude and explicit stigma of mental illness, and the intervention effectiveness on the stigma of mental illness in college students. \u0000 \u0000 \u0000Methods \u0000Single category implicit association test(SC-IAT) and questionnaire survey were used to study the degree of implicit and explicit mental illness stigma among 30 college students of Peking University, and investigated the effect of two strategies, education and contact.Data were analyzed by SPSS 22.0 with t-test and variance analysis. \u0000 \u0000 \u0000Results \u0000The D values of SC-IAT in the three dimensions of cognitive evaluation, emotional response and behavioral tendency of college students were 0.29±0.37, 0.24±0.43, and 0.10±0.43.There was a statistically significant difference between the cognitive evaluation dimension, the emotional response dimension and 0(t=4.069, P 0.05). The correct rates of questions \"Which of the following situations do you think are considered mentally unhealthy? \" and \"Which of the following disorders are mental illnesses\" (42±13)%, (54±13)%) increased after receiving educational intervention ((49±12)%, (64±13)%), the difference was statistically significant (F=3.682, P<0.05; F=3.576, P<0.05). \u0000 \u0000 \u0000Conclusion \u0000College students have implicit mental illness stigma, educational and contact intervention strategies can help improve college students' understanding of relevant knowledge, and cannot improve the level of implicit stigma of college students on mental illness. \u0000 \u0000 \u0000Key words: \u0000Mental illness stigma; Implicit stigma; Single category implicit association test; Stigma intervention","PeriodicalId":9940,"journal":{"name":"Chinese Journal of Behavioral Medicine and Brain Science","volume":"28 1","pages":"1010-1014"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48211326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To compare the difference of cognitive fusion, empirical avoidance between patients with obsessive-compulsive disorder and healthy control group, and to explore the relationship between obsessive-compulsive score and cognitive fusion, empirical avoidance. Methods The cognitive fusion questionnaire(CFQ), acceptance and action questionnaire-2nd edition(AAQ-II) and Yale-Brown scale for obsessive-compulsive symptoms (Y-BOCS) were used to investigate 100 subjects with obsessive-compulsive disorder (OCD) and 166 healthy controls.And the differences in cognitive fusion and empirical avoidance scores were compared between the two groups.The relationship of obsessive-compulsive symptoms and cognitive fusion, empirical avoidance was analyzed using multiple linear regression analysis. Results The scores of cognitive fusion ((49.89±10.62) vs (33.88±11.44), t=-11.345, P<0.01)and empirical avoidance ((29.75±9.53) vs (21.59±7.03), t=-7.995, P<0.01) in obsessive-compulsive disorder group were significantly higher than those in healthy control group.There were significant differences in cognitive fusion and empirical avoidance in age variables (F=8.63, P<0.01). In AAQ-Ⅱ, item 2 (r=0.246, P<0.05), item 6 (r=0.223, P<0.05) and total score (r=0.240, P<0.05) were positively correlated with the total score of Y-BOCS.Item 2 (r=0.311, P<0.01), item 3 (r=0.286, P<0.05), item 6 (r=0.248, P<0.05) and total score (r=0.229, P<0.05) were positively correlated with the scores of obsessive-thinking.In CFQ, item 2 (r=0.231, P<0.0) 5), item 4 (r=0.242, P<0.05), item 7 (r=0.308, P<0.05), item 8 (r=0.277, P<0.05) and item 9 (r=0.249, P<0.05) were positively correlated with the total score of Y-BOCS.Item 8 (r=0.261, P<0.05) was positively correlated with the scores of obsessive-thinking, item 7 (r=0.237, P<0.05) and item 9 (r=0.238, P<0.05) were positively correlated with scores of obsessive-compulsive behavior.When predicting total obsessive-compulsive scores, only CF item 7 of Q (B=1.827, P<0.01), item 3 (B=0.956, P<0.05), and item 6 of AAQ-Ⅱ (B=0.584, P<0.05) entered the equation with a joint explanatory variation of 19%.When predicting the score of obsessive-thinking, only item 2 of AAQ-Ⅱ (B=0.446, P<0.01) entered the equation, explaining the variance was 9.7%.In the prediction of obsessive-compulsive behavior, only item 9 (B=0.815, P<0.05) of CFQ entered the equation, and the explanatory variation was 5.6%. Conclusion Cognitive fusion in the patients with obsessive-compulsive disorder and the high level of empirical avoidance may be an important factor for the maintenance of the symptoms. Key words: Obsessive-compulsive disorder; Cognitive fusion; Empirical avoidance; Acceptance and commitment therapy
{"title":"Relationship between cognitive fusion, empirical avoidance and obsessive-compulsive symptoms in patients with obsessive-compulsive disorder","authors":"Lifang Qiu, Jian Liu, Wenxin Tang, Cuiru Yang, Cheng Zhu, Xia Zhao, Wenjing Zhu","doi":"10.3760/CMA.J.ISSN.1674-6554.2019.11.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-6554.2019.11.008","url":null,"abstract":"Objective \u0000To compare the difference of cognitive fusion, empirical avoidance between patients with obsessive-compulsive disorder and healthy control group, and to explore the relationship between obsessive-compulsive score and cognitive fusion, empirical avoidance. \u0000 \u0000 \u0000Methods \u0000The cognitive fusion questionnaire(CFQ), acceptance and action questionnaire-2nd edition(AAQ-II) and Yale-Brown scale for obsessive-compulsive symptoms (Y-BOCS) were used to investigate 100 subjects with obsessive-compulsive disorder (OCD) and 166 healthy controls.And the differences in cognitive fusion and empirical avoidance scores were compared between the two groups.The relationship of obsessive-compulsive symptoms and cognitive fusion, empirical avoidance was analyzed using multiple linear regression analysis. \u0000 \u0000 \u0000Results \u0000The scores of cognitive fusion ((49.89±10.62) vs (33.88±11.44), t=-11.345, P<0.01)and empirical avoidance ((29.75±9.53) vs (21.59±7.03), t=-7.995, P<0.01) in obsessive-compulsive disorder group were significantly higher than those in healthy control group.There were significant differences in cognitive fusion and empirical avoidance in age variables (F=8.63, P<0.01). In AAQ-Ⅱ, item 2 (r=0.246, P<0.05), item 6 (r=0.223, P<0.05) and total score (r=0.240, P<0.05) were positively correlated with the total score of Y-BOCS.Item 2 (r=0.311, P<0.01), item 3 (r=0.286, P<0.05), item 6 (r=0.248, P<0.05) and total score (r=0.229, P<0.05) were positively correlated with the scores of obsessive-thinking.In CFQ, item 2 (r=0.231, P<0.0) 5), item 4 (r=0.242, P<0.05), item 7 (r=0.308, P<0.05), item 8 (r=0.277, P<0.05) and item 9 (r=0.249, P<0.05) were positively correlated with the total score of Y-BOCS.Item 8 (r=0.261, P<0.05) was positively correlated with the scores of obsessive-thinking, item 7 (r=0.237, P<0.05) and item 9 (r=0.238, P<0.05) were positively correlated with scores of obsessive-compulsive behavior.When predicting total obsessive-compulsive scores, only CF item 7 of Q (B=1.827, P<0.01), item 3 (B=0.956, P<0.05), and item 6 of AAQ-Ⅱ (B=0.584, P<0.05) entered the equation with a joint explanatory variation of 19%.When predicting the score of obsessive-thinking, only item 2 of AAQ-Ⅱ (B=0.446, P<0.01) entered the equation, explaining the variance was 9.7%.In the prediction of obsessive-compulsive behavior, only item 9 (B=0.815, P<0.05) of CFQ entered the equation, and the explanatory variation was 5.6%. \u0000 \u0000 \u0000Conclusion \u0000Cognitive fusion in the patients with obsessive-compulsive disorder and the high level of empirical avoidance may be an important factor for the maintenance of the symptoms. \u0000 \u0000 \u0000Key words: \u0000Obsessive-compulsive disorder; Cognitive fusion; Empirical avoidance; Acceptance and commitment therapy","PeriodicalId":9940,"journal":{"name":"Chinese Journal of Behavioral Medicine and Brain Science","volume":"28 1","pages":"999-1004"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43868483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-20DOI: 10.3760/CMA.J.ISSN.1674-6554.2019.11.012
Yan-zhang Li, Mei-Jia Xiong, Yuping Zhang
Objective To explore the current status and predictive factors of frailty among community-dwelling old adults. Methods A total of 1 012 community-dwelling older adults aged 65 years and above in Sichuan Province were enrolled and investigated by self-made general condition scale, Tilburg Frailty Indicator (TFI), Short Physical Performance Battery(SPPB), 10-item Connor-Davidson Resilience Scale(CD-RISC-10), Mini-Mental State Examination(MMSE) and Geriatric Depression Scale Short-form(GDS-15). Results (1) The prevalence of frailty was 30.73%.(2) There were significant differences in the frailty scores of community-dwelling older adults in terms of gender, education, marital status, living condition, spouse support, children support, family economic conditions, self-perceived health status, number of chronic diseases, body mass index, number of falls in the past year, exercise state and sleep time at night(all P<0.05). (3) The frailty (3.72±2.88) was significantly positively correlated with depression (2.69±2.58; r=0.58, P<0.01), and negatively correlated with the scores of balance ability(3.28±1.01), walking speed(2.92±1.05), chair rise test(2.92±1.27), strength of resilience(13.99±3.57) and MMSE(23.71±5.55) (r=-0.33-0.43, P<0.01). (4) Depression (β=0.416, P<0.001), the number of chronic diseases(β=0.219, P<0.001), balance ability(β=-0.166, P<0.001), spousal support(β=-0.089, P<0.01), strength of resilience(β =-0.097, P<0.01), family economic status(β=0.093, P<0.01) and gender(β=0.082, P<0.01) significantly influenced frailty, with a combined explanation variance of 45.9%. Conclusions The rate of frailty of community-dwelling old adults is high, which is influenced by physiological, psychological and social factors.Therefore, it is necessary to adopt a comprehensive model of multi-disciplinary cooperation to carry out frailty intervention in community. Key words: Frailty; Influencing factor; Community-dwelling old adults
{"title":"The current status and influencing factors of frailty among community-dwelling old adults","authors":"Yan-zhang Li, Mei-Jia Xiong, Yuping Zhang","doi":"10.3760/CMA.J.ISSN.1674-6554.2019.11.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-6554.2019.11.012","url":null,"abstract":"Objective \u0000To explore the current status and predictive factors of frailty among community-dwelling old adults. \u0000 \u0000 \u0000Methods \u0000A total of 1 012 community-dwelling older adults aged 65 years and above in Sichuan Province were enrolled and investigated by self-made general condition scale, Tilburg Frailty Indicator (TFI), Short Physical Performance Battery(SPPB), 10-item Connor-Davidson Resilience Scale(CD-RISC-10), Mini-Mental State Examination(MMSE) and Geriatric Depression Scale Short-form(GDS-15). \u0000 \u0000 \u0000Results \u0000(1) The prevalence of frailty was 30.73%.(2) There were significant differences in the frailty scores of community-dwelling older adults in terms of gender, education, marital status, living condition, spouse support, children support, family economic conditions, self-perceived health status, number of chronic diseases, body mass index, number of falls in the past year, exercise state and sleep time at night(all P<0.05). (3) The frailty (3.72±2.88) was significantly positively correlated with depression (2.69±2.58; r=0.58, P<0.01), and negatively correlated with the scores of balance ability(3.28±1.01), walking speed(2.92±1.05), chair rise test(2.92±1.27), strength of resilience(13.99±3.57) and MMSE(23.71±5.55) (r=-0.33-0.43, P<0.01). (4) Depression (β=0.416, P<0.001), the number of chronic diseases(β=0.219, P<0.001), balance ability(β=-0.166, P<0.001), spousal support(β=-0.089, P<0.01), strength of resilience(β =-0.097, P<0.01), family economic status(β=0.093, P<0.01) and gender(β=0.082, P<0.01) significantly influenced frailty, with a combined explanation variance of 45.9%. \u0000 \u0000 \u0000Conclusions \u0000The rate of frailty of community-dwelling old adults is high, which is influenced by physiological, psychological and social factors.Therefore, it is necessary to adopt a comprehensive model of multi-disciplinary cooperation to carry out frailty intervention in community. \u0000 \u0000 \u0000Key words: \u0000Frailty; Influencing factor; Community-dwelling old adults","PeriodicalId":9940,"journal":{"name":"Chinese Journal of Behavioral Medicine and Brain Science","volume":"28 1","pages":"1020-1024"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43285380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-20DOI: 10.3760/CMA.J.ISSN.1674-6554.2019.11.003
W. Qian, Leng Hui, L. Xiao, Guo Feifei, Sun Xiangrong, G. Shengli, Xu Luo
Objective To investigate whether γ-aminobutyric acid (GABA) receptor signaling pathway is involved in the regulation of thalamic undefined (ZI)-nucleus accumbens (NAc) neural pathways on gastric distraction (GD)-sensitive neuronal firing activity and the impact on food intake, the number of times and the frequency in rats. Methods Six rats were randomly selected and the neural pathway between ZI and NAc in rat thalamus was observed by fluorescent gold (FG) retrograde tracing method.Eighty-two rats were randomly selected, and the gastric balloon was placed in gastric cavity, the microelectrode was placed in the NAc, and the stimulating electrode was placed in the ZI. The single-cell discharge recording method was used to observe the effect of electrical stimulation ZI on the excitability of GD-sensitive neurons in rat NAc.Eighteen rats were randomly selected and were divided into three groups according to the random number table. They were NS group, GABA group, GABA + GABA receptor antagonist bicuculline (BIC) group with 6 in each group, and the rat NAc was used to embed the cannula. The method of GABA and BIC was injected to observe the changes of cumulative food intake in rats for 4 h. Eighteen rats were randomly selected and randomly divided into three groups: sham stimulation (SS) group, 50 μA electrical stimulation group, 50 μA electrical stimulation + BIC group with 6 in each group. The 4 h cumulative food intake of rats was observed by electro-stimulation of rat ZI and rat NAc injection of BIC. Results Fluorescent gold retrograde tracking combined with fluorescent immunohistochemical staining showed that there were visible GABA and fluorescent gold double labeled neurons in ZI. Electrical stimulation of ZI, the frequency of GABA-sensitive GD neurons in rat NAc increased significantly (GD-E increase: (78.8±8.4)%, GD-I increase: (89.3±9.2)%, P<0.01), but the inhibitory effect was antagonized by BIC (GD-E increase: (113.8±13.6)%, GD-I increase: (121.8±14.2)%, P<0.01). Microinjection of GABA in rat NAc significantly increased the cumulative food intake for 4 h ((155.72±18.84) kcal, t=3.41, P<0.05), which was antagonized by partial BIC (123.43±15.11) kcal, t=3.28, P<0.05). Electrical stimulation of ZI significantly increased the food intake in rats ((39.07±11.27) kcal, t=2.96, P<0.05), and this effect can be partially antagonized by BIC ((34.17±10.85)kcal, t=2.33, P<0.05). Conclusion The ZI-NAc neural pathway regulates the discharge activity of rat gastric distension (GD)-sensitive neurons and the feeding status of rats, and the GABA receptor signaling pathway may be involved in mediating the process. Key words: Zona incerta; Nucleus accumbens; γ-aminobutyric acid; Gastric distension-sensitive neurons; Feeding
{"title":"Effects of γ-aminobutyric acid on feeding changes in rats and its potential mechanism","authors":"W. Qian, Leng Hui, L. Xiao, Guo Feifei, Sun Xiangrong, G. Shengli, Xu Luo","doi":"10.3760/CMA.J.ISSN.1674-6554.2019.11.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-6554.2019.11.003","url":null,"abstract":"Objective \u0000To investigate whether γ-aminobutyric acid (GABA) receptor signaling pathway is involved in the regulation of thalamic undefined (ZI)-nucleus accumbens (NAc) neural pathways on gastric distraction (GD)-sensitive neuronal firing activity and the impact on food intake, the number of times and the frequency in rats. \u0000 \u0000 \u0000Methods \u0000Six rats were randomly selected and the neural pathway between ZI and NAc in rat thalamus was observed by fluorescent gold (FG) retrograde tracing method.Eighty-two rats were randomly selected, and the gastric balloon was placed in gastric cavity, the microelectrode was placed in the NAc, and the stimulating electrode was placed in the ZI. The single-cell discharge recording method was used to observe the effect of electrical stimulation ZI on the excitability of GD-sensitive neurons in rat NAc.Eighteen rats were randomly selected and were divided into three groups according to the random number table. They were NS group, GABA group, GABA + GABA receptor antagonist bicuculline (BIC) group with 6 in each group, and the rat NAc was used to embed the cannula. The method of GABA and BIC was injected to observe the changes of cumulative food intake in rats for 4 h. Eighteen rats were randomly selected and randomly divided into three groups: sham stimulation (SS) group, 50 μA electrical stimulation group, 50 μA electrical stimulation + BIC group with 6 in each group. The 4 h cumulative food intake of rats was observed by electro-stimulation of rat ZI and rat NAc injection of BIC. \u0000 \u0000 \u0000Results \u0000Fluorescent gold retrograde tracking combined with fluorescent immunohistochemical staining showed that there were visible GABA and fluorescent gold double labeled neurons in ZI. Electrical stimulation of ZI, the frequency of GABA-sensitive GD neurons in rat NAc increased significantly (GD-E increase: (78.8±8.4)%, GD-I increase: (89.3±9.2)%, P<0.01), but the inhibitory effect was antagonized by BIC (GD-E increase: (113.8±13.6)%, GD-I increase: (121.8±14.2)%, P<0.01). Microinjection of GABA in rat NAc significantly increased the cumulative food intake for 4 h ((155.72±18.84) kcal, t=3.41, P<0.05), which was antagonized by partial BIC (123.43±15.11) kcal, t=3.28, P<0.05). Electrical stimulation of ZI significantly increased the food intake in rats ((39.07±11.27) kcal, t=2.96, P<0.05), and this effect can be partially antagonized by BIC ((34.17±10.85)kcal, t=2.33, P<0.05). \u0000 \u0000 \u0000Conclusion \u0000The ZI-NAc neural pathway regulates the discharge activity of rat gastric distension (GD)-sensitive neurons and the feeding status of rats, and the GABA receptor signaling pathway may be involved in mediating the process. \u0000 \u0000 \u0000Key words: \u0000Zona incerta; Nucleus accumbens; γ-aminobutyric acid; Gastric distension-sensitive neurons; Feeding","PeriodicalId":9940,"journal":{"name":"Chinese Journal of Behavioral Medicine and Brain Science","volume":"28 1","pages":"971-977"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42481149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-20DOI: 10.3760/CMA.J.ISSN.1674-6554.2019.11.015
Zhou Wang, Qian Bian, J. He, Jingping Shu, Yaping Kong, Lulu Yang, Jie Zhou, Shanshan Chen
Objective To examine the reliability and validity of the Columbia suicide screen (CSS) in detecting suicide risk for junior middle school students. Methods Using convenient sampling, 902 students of a junior middle school were tested with CSS and Beck depression inventory (BDI) .Cronbach's alpha coefficient, parity split-half coefficient and test-retest reliability were examined after two weeks.Content validity was evaluated using specialist analysis and sensibility analysis.The BDI was used to explore the correlative validity.The convergent validity of CSS and another suicide risk screening method was examined. Results The proportion of students with suicide problem (suicide ideation or suicide attempts), suicide ideation within the previous year and suicide attempts in the past were 14.97%(135/902), 14.19%(128/902)and 3.66%(33/902) respectively.The Cronbach's alpha coefficient and Parity split-half coefficient of CSS were 0.844 and 0.908, respectively.The test-retest reliability of CSS were screening of suicide ideation (ICC=0.897), screening of suicide attempts (ICC=0.798), screening of substance use (ICC=0.882), screening of suicide problem (ICC=0.881), and screening of suicide problem combine depression (ICC=0.829) (P<0.01). Sensibility analysis of CSS showed the cronbach α ranged from 0.834 to 0.845.Correlative validity between CSS and BDI were screening of suicide ideation(ρ=0.238, 0.337, 0.334, 0.599), screening of suicide attempts(ρ=0.122, 0.231, 0.310, 0.221), screening of depression(ρ=0.335, 0.309, 0.196, 0.215), screening of suicide problem(ρ=0.240, 0.328, 0.321, 0.590)and screening of suicide problem combine depression(ρ=0.212, 0.324, 0.320, 0.474)(P<0.01). Convergent validity between CSS and another suicide risk screening method were screening of suicide ideation(ρ=0.468), screening of suicide attempts(ρ=0.349), screening of suicide problem(ρ=0.453), and screening of suicide problem combine depression(ρ=0.469)(P<0.01). Conclusion CSS has good internal consistency reliability, split-half reliability and content validity.Screening of suicide ideation, suicide attempts, suicide problem and suicide problem combine depression have good test-retest reliability, but the correlative validity and convergent validity are not satisfying.These four screening methods can only be used for preliminary screening suicide risk in junior middle school students. Key words: Columbia Suicide Screen; Suicide; Reliability; Validity; Junior middle school student
{"title":"Reliability and validity of the Columbia suicide screen in junior middle school students","authors":"Zhou Wang, Qian Bian, J. He, Jingping Shu, Yaping Kong, Lulu Yang, Jie Zhou, Shanshan Chen","doi":"10.3760/CMA.J.ISSN.1674-6554.2019.11.015","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-6554.2019.11.015","url":null,"abstract":"Objective \u0000To examine the reliability and validity of the Columbia suicide screen (CSS) in detecting suicide risk for junior middle school students. \u0000 \u0000 \u0000Methods \u0000Using convenient sampling, 902 students of a junior middle school were tested with CSS and Beck depression inventory (BDI) .Cronbach's alpha coefficient, parity split-half coefficient and test-retest reliability were examined after two weeks.Content validity was evaluated using specialist analysis and sensibility analysis.The BDI was used to explore the correlative validity.The convergent validity of CSS and another suicide risk screening method was examined. \u0000 \u0000 \u0000Results \u0000The proportion of students with suicide problem (suicide ideation or suicide attempts), suicide ideation within the previous year and suicide attempts in the past were 14.97%(135/902), 14.19%(128/902)and 3.66%(33/902) respectively.The Cronbach's alpha coefficient and Parity split-half coefficient of CSS were 0.844 and 0.908, respectively.The test-retest reliability of CSS were screening of suicide ideation (ICC=0.897), screening of suicide attempts (ICC=0.798), screening of substance use (ICC=0.882), screening of suicide problem (ICC=0.881), and screening of suicide problem combine depression (ICC=0.829) (P<0.01). Sensibility analysis of CSS showed the cronbach α ranged from 0.834 to 0.845.Correlative validity between CSS and BDI were screening of suicide ideation(ρ=0.238, 0.337, 0.334, 0.599), screening of suicide attempts(ρ=0.122, 0.231, 0.310, 0.221), screening of depression(ρ=0.335, 0.309, 0.196, 0.215), screening of suicide problem(ρ=0.240, 0.328, 0.321, 0.590)and screening of suicide problem combine depression(ρ=0.212, 0.324, 0.320, 0.474)(P<0.01). Convergent validity between CSS and another suicide risk screening method were screening of suicide ideation(ρ=0.468), screening of suicide attempts(ρ=0.349), screening of suicide problem(ρ=0.453), and screening of suicide problem combine depression(ρ=0.469)(P<0.01). \u0000 \u0000 \u0000Conclusion \u0000CSS has good internal consistency reliability, split-half reliability and content validity.Screening of suicide ideation, suicide attempts, suicide problem and suicide problem combine depression have good test-retest reliability, but the correlative validity and convergent validity are not satisfying.These four screening methods can only be used for preliminary screening suicide risk in junior middle school students. \u0000 \u0000 \u0000Key words: \u0000Columbia Suicide Screen; Suicide; Reliability; Validity; Junior middle school student","PeriodicalId":9940,"journal":{"name":"Chinese Journal of Behavioral Medicine and Brain Science","volume":"28 1","pages":"1037-1042"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46257240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-20DOI: 10.3760/CMA.J.ISSN.1674-6554.2019.11.001
Fangling Sun, Min Liu, X. Tian, Tingting Liu, Y. Shan, P. Wei, Xiaotong Fan, Deyu Guo, Wen Wang, Guoguang Zhao
Objective To construct a scientific behavioral research of pasta matrix reaching task (PMRT) and comprehensively evaluate sensory-motor dysfunction caused by brain injury. Methods Twenty-one SD rats were subjected to 14-days pasta matrix grasping training and then were randomly divided into model group (11 rats) and sham group (6 rats). Motor cortex ischemia was induced by injection of endothelin-1 in SD rats. The number of pasta grabed by the injured forelimb and the location in matrix were evaluated daily 7 days after surgery. The infarct volume was measured by Nissl staining at the 7 days, 14 days, and 28 days after stroke. Results The number of pasta obtained by rats was reduced from (33.43±1.02) to (20.57±0.57) at 7 days post stroke in model group, and then increased to (26.85±0.98) at 28 days post stroke, although there was a significant difference between sham group(32.33±1.45) and ischemic group (t=3.198, P<0.05). The frequency of retrieval from each slot of the pasta matrix represented that sham group demonstrated a significant gain in performance in the antero quadrant of the matrix compared to ischemic rats by the fourth week after stroke.The stroke volume was decreased from (37.82±1.17)mm3 at 7 days post-stroke to (24.35±0.38)mm3 at 28 days post-stroke, indicating brain recovery from ischemic injury. Conclusion The pasta matrix reaching task can function as a versatile and sensitive behavioral assay that permits experimenters to collect accurate outcome data and manipulate limb use to mimic human clinical phenomena including compensatory strategies and focused rehabilitative training after stroke. Key words: Pasta matrix reaching task; Motor function; Infarct volume; Cerebral ischemia; Rat
{"title":"Application of pasta matrix reaching task in rats for forelimb motor function test after stroke","authors":"Fangling Sun, Min Liu, X. Tian, Tingting Liu, Y. Shan, P. Wei, Xiaotong Fan, Deyu Guo, Wen Wang, Guoguang Zhao","doi":"10.3760/CMA.J.ISSN.1674-6554.2019.11.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-6554.2019.11.001","url":null,"abstract":"Objective \u0000To construct a scientific behavioral research of pasta matrix reaching task (PMRT) and comprehensively evaluate sensory-motor dysfunction caused by brain injury. \u0000 \u0000 \u0000Methods \u0000Twenty-one SD rats were subjected to 14-days pasta matrix grasping training and then were randomly divided into model group (11 rats) and sham group (6 rats). Motor cortex ischemia was induced by injection of endothelin-1 in SD rats. The number of pasta grabed by the injured forelimb and the location in matrix were evaluated daily 7 days after surgery. The infarct volume was measured by Nissl staining at the 7 days, 14 days, and 28 days after stroke. \u0000 \u0000 \u0000Results \u0000The number of pasta obtained by rats was reduced from (33.43±1.02) to (20.57±0.57) at 7 days post stroke in model group, and then increased to (26.85±0.98) at 28 days post stroke, although there was a significant difference between sham group(32.33±1.45) and ischemic group (t=3.198, P<0.05). The frequency of retrieval from each slot of the pasta matrix represented that sham group demonstrated a significant gain in performance in the antero quadrant of the matrix compared to ischemic rats by the fourth week after stroke.The stroke volume was decreased from (37.82±1.17)mm3 at 7 days post-stroke to (24.35±0.38)mm3 at 28 days post-stroke, indicating brain recovery from ischemic injury. \u0000 \u0000 \u0000Conclusion \u0000The pasta matrix reaching task can function as a versatile and sensitive behavioral assay that permits experimenters to collect accurate outcome data and manipulate limb use to mimic human clinical phenomena including compensatory strategies and focused rehabilitative training after stroke. \u0000 \u0000 \u0000Key words: \u0000Pasta matrix reaching task; Motor function; Infarct volume; Cerebral ischemia; Rat","PeriodicalId":9940,"journal":{"name":"Chinese Journal of Behavioral Medicine and Brain Science","volume":"28 1","pages":"961-966"},"PeriodicalIF":0.0,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43126115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-20DOI: 10.3760/CMA.J.ISSN.1674-6554.2019.10.013
X. Tu, Yixuan Lin, Jia-jun Yan, Guohua Zhang
Objective To explore the relationship between impulsiveness and risky decision-making among college students with pathological internet use (PIU), as well as the moderating role of self-control. Methods Totally 542 undergraduates anonymously completed the Internet Addiction Test (IAT), Chinese Version of Barratt Impulsiveness Scale, Risk Preference Questionnaire, Self-Control Scale. Results (1)In loss frames, the scores of risky decision-making with high (20.26±4.83) and medium (20.40±5.53) level of impulsiveness among college students with PIU significantly were higher than those with low (18.92±5.03) level of impulsiveness (F(2, 323)=3.79, P<0.05, η2=0.02). (2)There was a significant negative correlation between impulsiveness (60.68±10.40) and self-control (55.56±9.07)(r=-0.60, P<0.01). And there was a significant positive correlations between impulsiveness and risky decision-making in loss frames (20.12±5.26)(r=0.13, P<0.05). The risky decision-making in gain frames (17.17±4.38) was positively correlated with that in loss frames (r=0.52, P<0.01). (3)Self-control played a moderating role in the association between impulsiveness and risky decision-making in loss frames (β=0.13, t=2.31, P<0.05). Conclusion In loss frames, impulsiveness is positively related with risky decision-making, and self-control plays a moderating role between impulsiveness and risky decision-making in loss frames among college students with PIU. Key words: College students; Pathological internet use; Impulsiveness; Risky decision-making; Self-control
{"title":"The moderating role of self-control between impulsiveness and risky decision-making among college students with pathological internet use","authors":"X. Tu, Yixuan Lin, Jia-jun Yan, Guohua Zhang","doi":"10.3760/CMA.J.ISSN.1674-6554.2019.10.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-6554.2019.10.013","url":null,"abstract":"Objective \u0000To explore the relationship between impulsiveness and risky decision-making among college students with pathological internet use (PIU), as well as the moderating role of self-control. \u0000 \u0000 \u0000Methods \u0000Totally 542 undergraduates anonymously completed the Internet Addiction Test (IAT), Chinese Version of Barratt Impulsiveness Scale, Risk Preference Questionnaire, Self-Control Scale. \u0000 \u0000 \u0000Results \u0000(1)In loss frames, the scores of risky decision-making with high (20.26±4.83) and medium (20.40±5.53) level of impulsiveness among college students with PIU significantly were higher than those with low (18.92±5.03) level of impulsiveness (F(2, 323)=3.79, P<0.05, η2=0.02). (2)There was a significant negative correlation between impulsiveness (60.68±10.40) and self-control (55.56±9.07)(r=-0.60, P<0.01). And there was a significant positive correlations between impulsiveness and risky decision-making in loss frames (20.12±5.26)(r=0.13, P<0.05). The risky decision-making in gain frames (17.17±4.38) was positively correlated with that in loss frames (r=0.52, P<0.01). (3)Self-control played a moderating role in the association between impulsiveness and risky decision-making in loss frames (β=0.13, t=2.31, P<0.05). \u0000 \u0000 \u0000Conclusion \u0000In loss frames, impulsiveness is positively related with risky decision-making, and self-control plays a moderating role between impulsiveness and risky decision-making in loss frames among college students with PIU. \u0000 \u0000 \u0000Key words: \u0000College students; Pathological internet use; Impulsiveness; Risky decision-making; Self-control","PeriodicalId":9940,"journal":{"name":"Chinese Journal of Behavioral Medicine and Brain Science","volume":"28 1","pages":"930-934"},"PeriodicalIF":0.0,"publicationDate":"2019-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46969132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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