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Laser speckle contrast imaging with principal component and entropy analysis: a novel approach for depth-independent blood flow assessment. 基于主成分和熵分析的激光散斑对比成像:一种与深度无关的血流评估新方法。
IF 4.1 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-01-03 DOI: 10.1007/s12200-024-00143-1
Yu Surkov, P Timoshina, I Serebryakova, D Stavtcev, I Kozlov, G Piavchenko, I Meglinski, A Konovalov, D Telyshev, S Kuznetcov, E Genina, V Tuchin

Current study presents an advanced method for improving the visualization of subsurface blood vessels using laser speckle contrast imaging (LSCI), enhanced through principal component analysis (PCA) filtering. By combining LSCI and laser speckle entropy imaging with PCA filtering, the method effectively separates static and dynamic components of the speckle signal, significantly improving the accuracy of blood flow assessments, even in the presence of static scattering layers located above and below the vessel. Experiments conducted on optical phantoms, with the vessel depths ranging from 0.6 to 2 mm, and in vivo studies on a laboratory mouse ear demonstrate substantial improvements in image contrast and resolution. The method's sensitivity to blood flow velocity within the physiologic range (0.98-19.66 mm/s) is significantly enhanced, while its sensitivity to vessel depth is minimized. These results highlight the method's ability to assess blood flow velocity independently of vessel depth, overcoming a major limitation of conventional LSCI techniques. The proposed approach holds great potential for non-invasive biomedical imaging, offering improved diagnostic accuracy and contrast in vascular imaging. These findings may be particularly valuable for advancing the use of LSCI in clinical diagnostics and biomedical research, where high precision in blood flow monitoring is essential.

目前,研究人员提出了一种先进的方法,通过主成分分析(PCA)滤波增强激光散斑对比成像(LSCI)来改善地下血管的可视化。该方法将LSCI和激光散斑熵成像与PCA滤波相结合,有效地分离了散斑信号的静态和动态分量,即使在血管上下存在静态散射层的情况下,也能显著提高血流评估的准确性。在光学幻影上进行的实验,血管深度范围从0.6到2mm,以及在实验室小鼠耳朵上的体内研究表明,图像对比度和分辨率有了实质性的改善。该方法对生理范围内(0.98 ~ 19.66 mm/s)血流速度的敏感性显著提高,而对血管深度的敏感性降低。这些结果突出了该方法独立于血管深度评估血流速度的能力,克服了传统LSCI技术的一个主要限制。该方法在非侵入性生物医学成像中具有很大的潜力,可以提高血管成像的诊断准确性和对比度。这些发现对于推进LSCI在临床诊断和生物医学研究中的应用可能特别有价值,在这些领域,高精度的血流监测是必不可少的。
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引用次数: 0
Optical logic array: a photonic solution towards universal computing. 光学逻辑阵列:面向通用计算的光子解决方案。
IF 4.1 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-12-25 DOI: 10.1007/s12200-024-00145-z
Lu Fang
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引用次数: 0
Mueller matrix polarimetry for quantitative evaluation of the Achilles tendon injury recovery. 穆勒矩阵偏振法定量评价跟腱损伤恢复。
IF 4.1 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-12-09 DOI: 10.1007/s12200-024-00142-2
Huibin Yang, Minhui Xu, Honghui He, Nan Zeng, Jiawei Song, Tongyu Huang, Ziyang Liang, Hui Ma

Achilles tendon injuries, as a widely existing disease, have attracted a lot of research interest. Mueller matrix polarimetry, as a novel label-free quantitative imaging method, has been widely used in various applications of lesion identification and pathological diagnosis. However, focusing on the recovery process of Achilles tendon injuries, current optical imaging methods have not yet achieved the label-free precise identification and quantitative evaluation. In this study, using Mueller matrix polarimetry, various Achilles tendon injury samples were characterized specifically, and the efficacy of different recovery schemes was evaluated accordingly. Experiments indicate that injured Achilles tendons show less phase retardance, larger diattenuation, and relatively disordered orientation. The combination of experiments with Monte Carlo simulation results illustrate the microscopic mechanism of the Achilles tendon recovery process from three aspects, that is, the increased fiber diameter, a more consistent fiber orientation, and greater birefringence induced by more collagen protein. Finally, based on the statistical distribution of polarization measurements, a polarization specific characterization parameter was extracted to construct a label-free image, which cannot only intuitively show the injury and recovery of Achilles tendon samples, but also give a quantitative evaluation of the treatment.

跟腱损伤作为一种广泛存在的疾病,引起了人们的广泛研究兴趣。穆勒矩阵偏振测量法作为一种新型的无标记定量成像方法,已被广泛应用于病变识别和病理诊断的各个领域。然而,针对跟腱损伤的恢复过程,目前的光学成像方法尚未实现无标记的精确识别和定量评价。本研究利用穆勒矩阵偏振法对各种跟腱损伤样本进行了特异性鉴定,并对不同恢复方案的功效进行了相应的评估。实验表明,受伤的跟腱显示出较小的相位延迟、较大的衰减和相对无序的取向。实验与蒙特卡洛模拟结果相结合,从三个方面说明了跟腱恢复过程的微观机制,即纤维直径增大、纤维取向更一致以及胶原蛋白增多导致双折射增大。最后,根据偏振测量值的统计分布,提取了偏振特异性表征参数,构建了无标记图像,不仅直观地显示了跟腱样本的损伤和恢复情况,还对治疗进行了定量评估。
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引用次数: 0
Influence of the homotopy stability perturbation on physical variations of non-local opto-electronic semiconductor materials. 同伦稳定性扰动对非局域光电半导体材料物理变化的影响。
IF 4.1 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-12-06 DOI: 10.1007/s12200-024-00141-3
A El-Dali, Mohamed I A Othman

In the current work, we investigate a novel technique specialized in stability perturbation theory to analyze the primary variations such as thermal, carrier, elastic, and mechanical waves in photothermal theory. The interface of the non-local semiconductor material is utilized to study the stability analysis. The problem is established using a 1D opto-electronic-thermoelastic deformation in the context of the photo-thermoelasticity (PTE) framework. The Laplace transform method is used to convert the system from the time domain into the frequency domain, and the boundary conditions for the thermal, elastic, and plasma waves are applied to the interface of the medium. The homotopy perturbation method was used as an innovative approach to analyze the stability of the non-local silicon's primary physical fields. The numerical inversion method is applied, yielding many graphs focusing on important numerical factors such as non-local effects, thermo-energy, and thermo-electric coupling parameters. Investigating dual solutions between stable and unstable regions for critical parameters like thermo-electric and thermo-energy coupling factors demonstrates that the homotopy perturbation technique can effectively analyze the stability analysis. The comparison between silicon and germanium is illustrated graphically. Utilizing the homotopy perturbation technique, we can effectively examine the stability of the primary physical variations with the effect of some values for eigenvalues approaches.

在当前的工作中,我们研究了一种专门用于稳定性微扰理论的新技术来分析光热理论中的主要变化,如热波、载流子波、弹性波和机械波。利用非局域半导体材料的界面进行稳定性分析。该问题是在光-热弹性(PTE)框架下使用一维光电-热弹性变形建立的。采用拉普拉斯变换方法将系统从时域转换到频域,并在介质界面上应用热波、弹性波和等离子体波的边界条件。采用同伦摄动法分析了非局域硅主物理场的稳定性。采用数值反演方法,得到了许多聚焦非局部效应、热能和热电耦合参数等重要数值因素的图。研究了热电和热能耦合因子等关键参数在稳定区和不稳定区之间的对偶解,证明了同伦摄动技术可以有效地分析稳定性分析。硅和锗的比较用图表说明了。利用同伦摄动技术,我们可以有效地检验特征值方法中某些值影响下的主要物理变化的稳定性。
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引用次数: 0
Correction: White light emission in 0D halide perovskite [(CH3)3S]2SnCl6·H2O crystals through variation of doping ns2 ions. 更正:0D 卤化物包晶 [(CH3)3S]2SnCl6-H2O 晶体中通过改变掺杂的 ns2 离子发出白光。
IF 4.1 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-11-12 DOI: 10.1007/s12200-024-00138-y
Yitong Lin, Yu Zhong, Yangpeng Lin, Jiawei Lin, Lei Pang, Zhilong Zhang, Yi Zhao, Xiao-Ying Huang, Ke-Zhao Du
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引用次数: 0
Multi-octave two-color soliton frequency comb in integrated chalcogenide microresonators. 集成卤素微谐振器中的多倍频程双色孤子频率梳。
IF 4.1 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-11-11 DOI: 10.1007/s12200-024-00139-x
Huanjie Cheng, Guosheng Lin, Di Xia, Liyang Luo, Siqi Lu, Changyuan Yu, Bin Zhang

Mid-infrared (MIR) Kerr microcombs are of significant interest for portable dual-comb spectroscopy and precision molecular sensing due to strong molecular vibrational absorption in the MIR band. However, achieving a compact, octave-spanning MIR Kerr microcomb remains a challenge due to the lack of suitable MIR photonic materials for the core and cladding of integrated devices and appropriate MIR continuous-wave (CW) pump lasers. Here, we propose a novel slot concentric dual-ring (SCDR) microresonator based on an integrated chalcogenide glass chip, which offers excellent transmission performance and flexible dispersion engineering in the MIR band. This device achieves both phase-matching and group velocity matching in two separated anomalous dispersion regions, enabling phase-locked, two-color solitons in the MIR region with a commercial 2-μm CW laser as the pump source. Moreover, the spectral locking of the two-color soliton enhances pump wavelength selectivity, providing precise control over soliton dynamics. By leveraging the dispersion characteristics of the SCDR microresonator, we have demonstrated a multi-octave-spanning, two-color soliton microcomb, covering a spectral range from 1156.07 to 5054.95 nm (200 THz) at a -40 dB level, highlighting the versatility and broad applicability of our approach. And the proposed multi-octave MIR frequency comb is relevant for applications such as dual-comb spectroscopy and trace-gas sensing.

由于中红外波段具有强烈的分子振动吸收,中红外(MIR)Kerr 微蜂窝对便携式双梳光谱仪和精密分子传感具有重大意义。然而,由于缺乏合适的中红外光子材料作为集成器件的核心和包层,也缺乏合适的中红外连续波(CW)泵浦激光器,因此实现紧凑、跨倍频程的中红外 Kerr 微蜂窝仍是一项挑战。在此,我们提出了一种基于集成钙化玻璃芯片的新型槽同心双环(SCDR)微谐振器,它在中红外波段具有出色的传输性能和灵活的色散工程。该器件在两个分离的反常色散区域实现了相位匹配和群速度匹配,从而能够在中红外波段使用商用 2-μm CW 激光作为泵浦源产生锁相双色孤子。此外,双色孤子的光谱锁定增强了泵浦波长的选择性,从而提供了对孤子动力学的精确控制。通过利用 SCDR 微谐振器的色散特性,我们展示了跨多倍频程的双色孤子微蜂窝,在 -40 dB 电平下覆盖了从 1156.07 到 5054.95 nm(200 THz)的光谱范围,突显了我们方法的多功能性和广泛适用性。所提出的多倍频程近红外频率梳适用于双梳光谱学和痕量气体传感等应用。
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引用次数: 0
Vehicular Mini-LED backlight display inspection based on residual global context mechanism. 基于残差全局上下文机制的车载微型 LED 背光显示检测。
IF 4.1 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-10-29 DOI: 10.1007/s12200-024-00140-4
Guobao Zhao, Xi Zheng, Xiao Huang, Yijun Lu, Zhong Chen, Weijie Guo

Mini-LED backlight has emerged as a promising technology for high performance LCDs, yet the massive detection of dead pixels and precise LEDs placement are constrained by the miniature scale of the Mini-LEDs. The high-resolution network (Hrnet) with mixed dilated convolution and dense upsampling convolution (MDC-DUC) module and a residual global context attention (RGCA) module has been proposed to detect the quality of vehicular Mini-LED backlights. The proposed model outperforms the baseline networks of Unet, Pspnet, Deeplabv3+, and Hrnet, with a mean intersection over union (Miou) of 86.91%. Furthermore, compared to the four baseline detection networks, our proposed model has a lower root-mean-square error (RMSE) when analyzing the position and defective count of Mini-LEDs in the prediction map by canny algorithm. This work incorporates deep learning to support production lines improve quality of Mini-LED backlights.

微型 LED 背光已成为高性能液晶显示器的一项前景广阔的技术,但由于微型 LED 的微型尺寸,大量检测死像素和精确放置 LED 都受到限制。我们提出了带有混合扩张卷积和密集上采样卷积(MDC-DUC)模块和残差全局上下文注意(RGCA)模块的高分辨率网络(Hrnet),用于检测车辆微型 LED 背光的质量。所提出的模型优于 Unet、Pspnet、Deeplabv3+ 和 Hrnet 等基线网络,平均交集大于联合(Miou)为 86.91%。此外,与四个基线检测网络相比,我们提出的模型在使用 canny 算法分析预测图中 Mini-LED 的位置和缺陷数时,具有更低的均方根误差(RMSE)。这项工作结合了深度学习,以支持生产线提高 Mini-LED 背光的质量。
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引用次数: 0
Plasma photonic crystal 'kaleidoscope' with flexible control of topology and electromagnetism. 可灵活控制拓扑结构和电磁的等离子光子晶体 "万花筒"。
IF 4.1 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-10-17 DOI: 10.1007/s12200-024-00137-z
Jing Wang, Shuang Liu, Weili Fan, Shuo Wang, Cuicui Lu, Yafeng He, Fucheng Liu, Xiaoyong Hu

Continuous development of photonic crystals (PCs) over the last 30 years has carved out many new scientific frontiers. However, creating tunable PCs that enable flexible control of geometric configurations remains a challenge. Here we present a scheme to produce a tunable plasma photonic crystal (PPC) 'kaleidoscope' with rich diversity of structural configurations in dielectric barrier discharge. Multi-freedom control of the PPCs, including the symmetry, dielectric constant, crystal orientation, lattice constant, topological state, and structures of scattering elements, has been realized. Four types of lattice reconfigurations are demonstrated, including transitions from periodic to periodic, disordered to ordered, non-topological to topological, and striped to honeycomb Moiré lattices. Furthermore, alterations in photonic band structures corresponding to the reconstruction of various PPCs have been investigated. Our system presents a promising platform for generating a PPC 'kaleidoscope', offering benefits such as reduced equipment requirements, low cost, rapid response, and enhanced flexibility. This development opens up new opportunities for both fundamental and applied research.

过去 30 年来,光子晶体(PC)的不断发展开拓了许多新的科学前沿。然而,要制造出能灵活控制几何构型的可调谐光子晶体仍是一项挑战。在这里,我们介绍了一种在介质阻挡放电中制造可调谐等离子体光子晶体(PPC)"万花筒 "的方案,它具有丰富多样的结构配置。我们实现了对等离子光子晶体的多自由度控制,包括对称性、介电常数、晶体取向、晶格常数、拓扑状态和散射元件的结构。演示了四种类型的晶格重构,包括从周期到周期、无序到有序、非拓扑到拓扑以及从条纹到蜂巢莫伊里晶格的转变。此外,我们还研究了光子带结构的变化,这些变化与各种 PPC 的重构相对应。我们的系统为生成 PPC "万花筒 "提供了一个前景广阔的平台,具有设备要求低、成本低、响应快和灵活性强等优点。这一发展为基础研究和应用研究开辟了新的机遇。
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引用次数: 0
Information processing at the speed of light. 光速信息处理
IF 4.1 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-09-29 DOI: 10.1007/s12200-024-00133-3
Muhammad AbuGhanem

In recent years, quantum computing has made significant strides, particularly in light-based technology. The introduction of quantum photonic chips has ushered in an era marked by scalability, stability, and cost-effectiveness, paving the way for innovative possibilities within compact footprints. This article provides a comprehensive exploration of photonic quantum computing, covering key aspects such as encoding information in photons, the merits of photonic qubits, and essential photonic device components including light squeezers, quantum light sources, interferometers, photodetectors, and waveguides. The article also examines photonic quantum communication and internet, and its implications for secure systems, detailing implementations such as quantum key distribution and long-distance communication. Emerging trends in quantum communication and essential reconfigurable elements for advancing photonic quantum internet are discussed. The review further navigates the path towards establishing scalable and fault-tolerant photonic quantum computers, highlighting quantum computational advantages achieved using photons. Additionally, the discussion extends to programmable photonic circuits, integrated photonics and transformative applications. Lastly, the review addresses prospects, implications, and challenges in photonic quantum computing, offering valuable insights into current advancements and promising future directions in this technology.

近年来,量子计算取得了长足进步,尤其是在基于光的技术方面。量子光子芯片的问世开创了一个以可扩展性、稳定性和成本效益为特点的时代,为在紧凑的空间内实现创新的可能性铺平了道路。本文对光子量子计算进行了全面探讨,涉及光子信息编码、光子量子比特的优点以及光子器件的基本组件(包括光挤压器、量子光源、干涉仪、光电探测器和波导)等关键方面。文章还探讨了光子量子通信和互联网及其对安全系统的影响,详细介绍了量子密钥分发和远距离通信等实现方法。文章还讨论了量子通信的新趋势以及推进光子量子互联网的基本可重构元素。该综述进一步探讨了建立可扩展和容错光子量子计算机的途径,强调了利用光子实现的量子计算优势。此外,还讨论了可编程光子电路、集成光子学和变革性应用。最后,综述探讨了光子量子计算的前景、影响和挑战,为该技术当前的进展和未来的发展方向提供了宝贵的见解。
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引用次数: 0
Quantitative modeling of perovskite-based direct X-ray flat panel detectors. 基于包晶石的直接 X 射线平板探测器的定量建模。
IF 4.1 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2024-09-26 DOI: 10.1007/s12200-024-00136-0
Zihao Song, Gaozhu Wang, Jincong Pang, Zhiping Zheng, Ling Xu, Ying Zhou, Guangda Niu, Jiang Tang

Direct X-ray detectors based on semiconductors have drawn great attention from researchers in the pursuing of higher imaging quality. However, many previous works focused on the optimization of detection performances but seldomly watch them in an overall view and analyze how they will influence the detective quantum efficiency (DQE) value. Here, we propose a numerical model which shows the quantitative relationship between DQE and the properties of X-ray detectors and electric circuits. Our results point out that pursuing high sensitivity only is meaningless. To reduce the medical X-ray dose by 80%, the requirement for X-ray sensitivity is only at a magnitude of 103 μCGy-1⋅cm-2. To achieve the DQE = 0.7 at X-ray sensitivity air from 1248 to 8171 μCGy-1air⋅cm-2, the requirements on dark current density ranges from 10 to 100 nA⋅cm-2 and the fluctuation of current density should fall in 0.21 to 1.37 nA⋅cm-2.

基于半导体的直接 X 射线探测器在追求更高的成像质量方面引起了研究人员的极大关注。然而,以往的许多研究都侧重于探测性能的优化,却很少从整体上观察和分析它们将如何影响探测量子效率(DQE)值。在此,我们提出了一个数值模型,该模型显示了 DQE 与 X 射线探测器和电路特性之间的定量关系。我们的研究结果表明,仅仅追求高灵敏度是没有意义的。要将医用 X 射线剂量降低 80%,对 X 射线灵敏度的要求仅为 103 μCGy-1-cm-2。要在 X 射线灵敏度为 1248 至 8171 μCGy-1air⋅cm-2 的空气中达到 DQE = 0.7,对暗电流密度的要求为 10 至 100 nA⋅cm-2 不等,电流密度的波动应在 0.21 至 1.37 nA⋅cm-2 之间。
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引用次数: 0
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Frontiers of Optoelectronics
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