Pub Date : 2024-01-30DOI: 10.30574/gscbps.2024.26.1.0013
Majedul Hoque, Rehnuma Jafreen, Maria Siddika Mim, Nafisa Tabassum
Background: A pathological condition called malnutrition arises when there is a relative or absolute lack or excess of one or more nutrients. In low-income nations, it is a serious public health issue for children under ten years. Malnutrition is a state of nutritional deficit brought on by insufficient consumption of protein or energy. Primary acute malnutrition in children is a prevalent condition in underdeveloped nations due to insufficient food supply resulting from social, economic, and environmental causes. An underlying illness that results in aberrant nutritional loss, increased energy expenditure, or decreased food intake is typically the cause of secondary acute malnutrition. Method: This was an observational, descriptive study conducted in Bangladesh's Narsingdi area from September to October 2023. All records of children with complications of malnutrition, between the ages of 2 and 10 were included in the study. Result: 142 children fall in the category of underweight, 166 children possess suitable BMI and 8 of them were heavyweight with BMI more than 23. Nearly one third of the children faces physical problems some times in their life time. Among all of the children 139 (43.98%) had perfect physical status with good health and diarrhea is the most common problem they caught by 118 respondents. Conclusion: In the district, its severity and prevalence can be decreased with increased community knowledge and stronger preventive efforts.
{"title":"Prevalence of malnutrition in children in Narsingdi district, Bangladesh: An observational study","authors":"Majedul Hoque, Rehnuma Jafreen, Maria Siddika Mim, Nafisa Tabassum","doi":"10.30574/gscbps.2024.26.1.0013","DOIUrl":"https://doi.org/10.30574/gscbps.2024.26.1.0013","url":null,"abstract":"Background: A pathological condition called malnutrition arises when there is a relative or absolute lack or excess of one or more nutrients. In low-income nations, it is a serious public health issue for children under ten years. Malnutrition is a state of nutritional deficit brought on by insufficient consumption of protein or energy. Primary acute malnutrition in children is a prevalent condition in underdeveloped nations due to insufficient food supply resulting from social, economic, and environmental causes. An underlying illness that results in aberrant nutritional loss, increased energy expenditure, or decreased food intake is typically the cause of secondary acute malnutrition. Method: This was an observational, descriptive study conducted in Bangladesh's Narsingdi area from September to October 2023. All records of children with complications of malnutrition, between the ages of 2 and 10 were included in the study. Result: 142 children fall in the category of underweight, 166 children possess suitable BMI and 8 of them were heavyweight with BMI more than 23. Nearly one third of the children faces physical problems some times in their life time. Among all of the children 139 (43.98%) had perfect physical status with good health and diarrhea is the most common problem they caught by 118 respondents. Conclusion: In the district, its severity and prevalence can be decreased with increased community knowledge and stronger preventive efforts.","PeriodicalId":12808,"journal":{"name":"GSC Biological and Pharmaceutical Sciences","volume":"1 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Toumanguié agricultural zone in the Sud-Comoé region of south-eastern Côte d'Ivoire contains several agricultural plantations and a dense and varied hydrographic system including the Bosso and Toumanguié rivers. However, knowledge of the ecological status of these two rivers is almost unavailable to the scientific community to assess the impact of agricultural activities. The purpose of this one-off study, carried out in March 2023, was to provide initial data on the physicochemical state and composition of macroinvertebrate communities in these two rivers. Four (4) sampling points were defined on these rivers. Measurements of the water physicochemical parameters (temperature, dissolved oxygen transparency, conductivity and pH) were taken in situ between 06:00 and 08:00 in the morning using a multiparameter, and some water samples were taken for the determination of nutrients. Macroinvertebrates were collected using a Van Veen bucket and a dip net. Analysis of the physicochemical parameters showed that the water in the Toumanguié agricultural zone was of relatively good quality and conducive to the survival of aquatic macroinvertebrates. However, the nutrient values indicated that the water was slightly polluted as a result of the degradation of organic matter. 34 taxa belonging to 26 families and 11 orders were identified, with a predominance of insects. Diptera were predominant. The taxa commonly collected in these rivers were: Cricotopus kisantuensis, Polypedilum fuscipenne, Chironominae and Diplonychus sp. The macroinvertebrate communities in these two rivers were not very diversified but were relatively balanced in terms of diversity index values.
{"title":"Preliminary data on the structure of macroinvertebrate communities and the physicochemical conditions of the Toumanguié and Bosso rivers under the influence of agricultural activities in the Aboisso department (south-east, Côte d'Ivoire)","authors":"Allouko Jean-Renaud, Kressou Armand, Traoré Awa, Bony Kotchi","doi":"10.30574/gscbps.2024.26.1.0542","DOIUrl":"https://doi.org/10.30574/gscbps.2024.26.1.0542","url":null,"abstract":"The Toumanguié agricultural zone in the Sud-Comoé region of south-eastern Côte d'Ivoire contains several agricultural plantations and a dense and varied hydrographic system including the Bosso and Toumanguié rivers. However, knowledge of the ecological status of these two rivers is almost unavailable to the scientific community to assess the impact of agricultural activities. The purpose of this one-off study, carried out in March 2023, was to provide initial data on the physicochemical state and composition of macroinvertebrate communities in these two rivers. Four (4) sampling points were defined on these rivers. Measurements of the water physicochemical parameters (temperature, dissolved oxygen transparency, conductivity and pH) were taken in situ between 06:00 and 08:00 in the morning using a multiparameter, and some water samples were taken for the determination of nutrients. Macroinvertebrates were collected using a Van Veen bucket and a dip net. Analysis of the physicochemical parameters showed that the water in the Toumanguié agricultural zone was of relatively good quality and conducive to the survival of aquatic macroinvertebrates. However, the nutrient values indicated that the water was slightly polluted as a result of the degradation of organic matter. 34 taxa belonging to 26 families and 11 orders were identified, with a predominance of insects. Diptera were predominant. The taxa commonly collected in these rivers were: Cricotopus kisantuensis, Polypedilum fuscipenne, Chironominae and Diplonychus sp. The macroinvertebrate communities in these two rivers were not very diversified but were relatively balanced in terms of diversity index values.","PeriodicalId":12808,"journal":{"name":"GSC Biological and Pharmaceutical Sciences","volume":"6 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-30DOI: 10.30574/gscbps.2024.26.1.0532
Yogesh Mishra
The present study in biofloc pond is an initiative in district Kaushambi Uttar Pradesh. The fish farmers have made biofloc ponds with some modifications in their fish culture ponds. The study was conducted during June to November month in 2022 in three village biofloc ponds of District Kaushambi. The fish farmers of Kaushambi belongs to rural area and lack awareness and training in relation to biofloc fish farming. The fish production in Chalauli and Malahipur biofloc Pond were 80 quintal and 42 quintals respectively against the seed stocking of 9000. In Myohar biofloc pond it was 30 quintals against the seed stocking of 8000. The fishes which are cultured in Biofloc are pangasianodon hypothalamus, clarias batracus, heteropneustis fossils and cirrhinus mrigala. Pangasiandon was found to be the most cultured species. Most of the farmers were found young, educated, least experienced and small-scale investors. Prevention of diseases and therapeutic measures were found satisfactory. The farmers were also not aware about carbon: nitrogen ratio but they try to maintain it.
{"title":"A study of freshwater fish farming of biofloc ponds in district Kaushambi Uttar Pradesh","authors":"Yogesh Mishra","doi":"10.30574/gscbps.2024.26.1.0532","DOIUrl":"https://doi.org/10.30574/gscbps.2024.26.1.0532","url":null,"abstract":"The present study in biofloc pond is an initiative in district Kaushambi Uttar Pradesh. The fish farmers have made biofloc ponds with some modifications in their fish culture ponds. The study was conducted during June to November month in 2022 in three village biofloc ponds of District Kaushambi. The fish farmers of Kaushambi belongs to rural area and lack awareness and training in relation to biofloc fish farming. The fish production in Chalauli and Malahipur biofloc Pond were 80 quintal and 42 quintals respectively against the seed stocking of 9000. In Myohar biofloc pond it was 30 quintals against the seed stocking of 8000. The fishes which are cultured in Biofloc are pangasianodon hypothalamus, clarias batracus, heteropneustis fossils and cirrhinus mrigala. Pangasiandon was found to be the most cultured species. Most of the farmers were found young, educated, least experienced and small-scale investors. Prevention of diseases and therapeutic measures were found satisfactory. The farmers were also not aware about carbon: nitrogen ratio but they try to maintain it.","PeriodicalId":12808,"journal":{"name":"GSC Biological and Pharmaceutical Sciences","volume":"438 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140479821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cervical cancer is a malignant tumor of the lowermost part of the uterus and a major cause of morbidity and mortality among women in the world. Globally, it is the fifth leading cause of cancer-related deaths among women after cancers of the breast, lungs, stomach and colorectal in developing countries. About 80% of new incidences of cervical cancer occur in developing countries, usually, with less comprehensive cervical cancer prevention programs. The objective of the study is to assess the level of knowledge on cervical cancer and Pap smear tests among Reproductive age group women. A descriptive study was conducted in Gokarneshwor-8, Kathmandu community on 105 respondents through non-probability purposive sampling techniques and data was collected using interviewers administered questionnaires. Out of 105 respondents, a majority (64%) respondents had adequate knowledge of cervical cancer and Pap smear tests, while 36% had inadequate knowledge. This study concluded that the majority of respondents had adequate knowledge of Pap smear tests while only thirty-six percent had inadequate knowledge. Though there is adequate knowledge, only a few respondents had ever done a Pap smear test. Still, there are existing gaps that need more education to connect knowledge with attitudes as well as to uplift the regular practice of cervical cancer screening for eligible women.
{"title":"Knowledge of Pap smear test among reproductive age group women of Kathmandu, Nepal","authors":"Rabindra Kumar Rokaya, Rajeena Moktan, Asmita Thapa, Pabina KC, Reshma KC, Priti Rawat, Sanjiv Kumar Pandey","doi":"10.30574/gscbps.2024.26.1.0546","DOIUrl":"https://doi.org/10.30574/gscbps.2024.26.1.0546","url":null,"abstract":"Cervical cancer is a malignant tumor of the lowermost part of the uterus and a major cause of morbidity and mortality among women in the world. Globally, it is the fifth leading cause of cancer-related deaths among women after cancers of the breast, lungs, stomach and colorectal in developing countries. About 80% of new incidences of cervical cancer occur in developing countries, usually, with less comprehensive cervical cancer prevention programs. The objective of the study is to assess the level of knowledge on cervical cancer and Pap smear tests among Reproductive age group women. A descriptive study was conducted in Gokarneshwor-8, Kathmandu community on 105 respondents through non-probability purposive sampling techniques and data was collected using interviewers administered questionnaires. Out of 105 respondents, a majority (64%) respondents had adequate knowledge of cervical cancer and Pap smear tests, while 36% had inadequate knowledge. This study concluded that the majority of respondents had adequate knowledge of Pap smear tests while only thirty-six percent had inadequate knowledge. Though there is adequate knowledge, only a few respondents had ever done a Pap smear test. Still, there are existing gaps that need more education to connect knowledge with attitudes as well as to uplift the regular practice of cervical cancer screening for eligible women.","PeriodicalId":12808,"journal":{"name":"GSC Biological and Pharmaceutical Sciences","volume":"6 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-30DOI: 10.30574/gscbps.2024.26.1.0524
Putri Arihtalia Br Purba, I Dewa Gede Arta Eka Putra
Introduction: Sialolithiasis is a disease in which calcified substances accumulate in the ducts or parenchyma of the salivary glands. This disease can occur in people of all ages but is mostly seen in middle-aged adults and rarely in children. This case report aimed to describe a case of sialolithiasis in children Case Report: A 3-year-old girl presented with a lump that enlarged progressively on the right side of the neck since 1 year ago. The patient also complained of painful swallowing. Palpation of the right submandibular revealed a solid, mobile mass measuring 0.5x0.5cm without tenderness or hyperemia. A neck ultrasound showed an enlarged submandibular gland and right parotid gland. A midface and neck multi-slice computed tomography scan (MSCT) supported the diagnosis of sialolithiasis. The patient underwent stone removal with an extraoral approach and general anesthesia. The patient then was discharged with cefixime, methylprednisolone, and paracetamol. Discussion: Sialolithiasis that cannot be removed by opening the canal can be removed by trans-oral or extra-oral sialolithotomy, extracorporeal lithotripsy, sialendoscopy, or laser treatment. Submandibular stones can be removed surgically by intraoral or extraoral approaches. Extraoral approaches are indicated for intra-glandular stones and stones embedded in the hilum of the gland. Conclusion: The diagnosis of sialolithiasis in this patient was confirmed through history taking, physical examination, ultrasound, and a CT scan. Management of sialolithiasis focuses on removing the stone and maintaining salivary gland function. In this case, the stone was removed using an extraoral approach under general anesthesia which resulted in a good outcome
{"title":"Sialolithiasis in children","authors":"Putri Arihtalia Br Purba, I Dewa Gede Arta Eka Putra","doi":"10.30574/gscbps.2024.26.1.0524","DOIUrl":"https://doi.org/10.30574/gscbps.2024.26.1.0524","url":null,"abstract":"Introduction: Sialolithiasis is a disease in which calcified substances accumulate in the ducts or parenchyma of the salivary glands. This disease can occur in people of all ages but is mostly seen in middle-aged adults and rarely in children. This case report aimed to describe a case of sialolithiasis in children Case Report: A 3-year-old girl presented with a lump that enlarged progressively on the right side of the neck since 1 year ago. The patient also complained of painful swallowing. Palpation of the right submandibular revealed a solid, mobile mass measuring 0.5x0.5cm without tenderness or hyperemia. A neck ultrasound showed an enlarged submandibular gland and right parotid gland. A midface and neck multi-slice computed tomography scan (MSCT) supported the diagnosis of sialolithiasis. The patient underwent stone removal with an extraoral approach and general anesthesia. The patient then was discharged with cefixime, methylprednisolone, and paracetamol. Discussion: Sialolithiasis that cannot be removed by opening the canal can be removed by trans-oral or extra-oral sialolithotomy, extracorporeal lithotripsy, sialendoscopy, or laser treatment. Submandibular stones can be removed surgically by intraoral or extraoral approaches. Extraoral approaches are indicated for intra-glandular stones and stones embedded in the hilum of the gland. Conclusion: The diagnosis of sialolithiasis in this patient was confirmed through history taking, physical examination, ultrasound, and a CT scan. Management of sialolithiasis focuses on removing the stone and maintaining salivary gland function. In this case, the stone was removed using an extraoral approach under general anesthesia which resulted in a good outcome","PeriodicalId":12808,"journal":{"name":"GSC Biological and Pharmaceutical Sciences","volume":"170 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140483796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The turtle population of Taï National Park (TNP), located in southwest Côte d'Ivoire, was surveyed to determine the diversity of turtles in this Park and to identify their preferred habitats. Data collection was carried out from April to October 2021 in different habitats of the park using the unmarked observation method. This method involved opportunistic sampling during reconnaissance walks for terrestrial species and baited traps were used for aquatic species. A total of four turtle species were recorded: two terrestrial species (Kinixys erosa and Kinixys homeana) and two aquatic species (Pelusios cupulatta and Trionyx triunguis). The turtle fauna study sites were composed of open undergrowth, closed undergrowth and swamp habitats for terrestrial turtles. Aquatic turtles were observed in the Meno River. According to the IUCN Red List, the species Kinixys homeana and Trionyx triunguis are classified as critically endangered and vulnerable respectively. As for the other two species, there is insufficient data to assess their international conservation status.
{"title":"The turtle fauna of a West African rainforest (Taï national park, Côte d’Ivoire)","authors":"Aya Blanche Prisca IRI, Konan Hervé OUSSOU, N’Guessan Emmanuel Assemian, Abdoulaye DIARRASSOUBA","doi":"10.30574/gscbps.2024.26.1.0008","DOIUrl":"https://doi.org/10.30574/gscbps.2024.26.1.0008","url":null,"abstract":"The turtle population of Taï National Park (TNP), located in southwest Côte d'Ivoire, was surveyed to determine the diversity of turtles in this Park and to identify their preferred habitats. Data collection was carried out from April to October 2021 in different habitats of the park using the unmarked observation method. This method involved opportunistic sampling during reconnaissance walks for terrestrial species and baited traps were used for aquatic species. A total of four turtle species were recorded: two terrestrial species (Kinixys erosa and Kinixys homeana) and two aquatic species (Pelusios cupulatta and Trionyx triunguis). The turtle fauna study sites were composed of open undergrowth, closed undergrowth and swamp habitats for terrestrial turtles. Aquatic turtles were observed in the Meno River. According to the IUCN Red List, the species Kinixys homeana and Trionyx triunguis are classified as critically endangered and vulnerable respectively. As for the other two species, there is insufficient data to assess their international conservation status.","PeriodicalId":12808,"journal":{"name":"GSC Biological and Pharmaceutical Sciences","volume":"201 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140481877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The use of medicinal plants as complementary therapies has lately grown in popularity. The aim of this study was to determine the chemical composition of the aqueous root extract of Gnetum africanum using GC-MS and GC-FID analysis. Fresh roots of G. africanum Welw used in this study were collected, cut into pieces, washed and air-dried. The dried plant materials were ground into powder and kept in an airtight container. GC-MS analysis of the aqueous root extract revealed 20 bioactive compounds with the following being most abundant 2,3-Butanediol as the predominant phytochemical at 46.02%, followed by Benzene, 1,4-dichloro (3.57%) and Oxalic acid, allyl octadecyl ester (3.45%). The quantitative GC-FID determination of the phytochemicals of Gnetum africanum aqueous root extract presented common phytochemicals such as, alkaloids, flavonoids, steroids, phenols and glycosides. Phytochemicals in higher proportions include; sapogenin (26.2645 µg/ml), anthocyanins (17.4986 µg/ml), cyanogenic glycosides (15.3616 µg/ml), kaempferol (13.7621 µg/ml) and flavan-3-ol (13.0446 µg/ml). It has been discovered that the root of Gnetum africanum contains an array of phytocompounds with a variety of therapeutic properties.
{"title":"Chemical Analysis of Gnetum africanum roots","authors":"Precious Uchenna Asonye, Chiedozie Onyejiaka Ibegbulem, Callistus Izunna Iheme, Goodness Chigozirim Iheonunekwu, Chinweuba Godswill Nwaekpe","doi":"10.30574/gscbps.2024.26.1.0547","DOIUrl":"https://doi.org/10.30574/gscbps.2024.26.1.0547","url":null,"abstract":"The use of medicinal plants as complementary therapies has lately grown in popularity. The aim of this study was to determine the chemical composition of the aqueous root extract of Gnetum africanum using GC-MS and GC-FID analysis. Fresh roots of G. africanum Welw used in this study were collected, cut into pieces, washed and air-dried. The dried plant materials were ground into powder and kept in an airtight container. GC-MS analysis of the aqueous root extract revealed 20 bioactive compounds with the following being most abundant 2,3-Butanediol as the predominant phytochemical at 46.02%, followed by Benzene, 1,4-dichloro (3.57%) and Oxalic acid, allyl octadecyl ester (3.45%). The quantitative GC-FID determination of the phytochemicals of Gnetum africanum aqueous root extract presented common phytochemicals such as, alkaloids, flavonoids, steroids, phenols and glycosides. Phytochemicals in higher proportions include; sapogenin (26.2645 µg/ml), anthocyanins (17.4986 µg/ml), cyanogenic glycosides (15.3616 µg/ml), kaempferol (13.7621 µg/ml) and flavan-3-ol (13.0446 µg/ml). It has been discovered that the root of Gnetum africanum contains an array of phytocompounds with a variety of therapeutic properties.","PeriodicalId":12808,"journal":{"name":"GSC Biological and Pharmaceutical Sciences","volume":"9 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-30DOI: 10.30574/gscbps.2024.26.1.0446
Utkarsha A. Wadighare, Swati P. Deshmukh
The cutting-edge upward push of artificial intelligence and system mastering has been of considerable size. It has reduced the human workload move forward exceptional of life exceptionally. This article describes using artificial intelligence and system learning to augment drug discovery and upgrade to lead them to more well organised and correct. In medication, specialties in which images are vitally important, like radiology, pathology or oncology, have seized the able to be done and full-size efforts in studies and development were deployed to switch the adaptness of AI to scientific packages. With AI becoming a extra widespread device for usual scientific imaging evaluation duties, together with prognosis, segmentation, or classification, the important thing for a secure and efficient use of medical AI packages. This body of work supported the jobs of system gaining knowledge of and synthetic intelligence in facilitating drug expansion and finding out methods, making them greater cost-powerful or altogether casting off the want for clinical trials, as a result of the potential to conduct simulations the usage of those technologies. Doing so will assist in separating wish from hype and lead to knowledgeable choice making at the top-quality use of AI/ML in drug development. Machine studying strategies can subterfuge complicated analyzes with huge, heterogeneous, and excessive dimensional information collections without a guide enter, which has proved helpful inside the writing commercial enterprise applications. Combining system mastering, particularly deep getting to know, with human skill and revel in is probably the great manner to coordinate numerous significant facts stores. The magnificent facts-mining capacity of AI innovation has given new essentiality to computer supported medication plans that incorporate more than one clinical concerns are higher than piecemeal data.
{"title":"A review on artificial intelligence and machine learning used in pharmaceutical research","authors":"Utkarsha A. Wadighare, Swati P. Deshmukh","doi":"10.30574/gscbps.2024.26.1.0446","DOIUrl":"https://doi.org/10.30574/gscbps.2024.26.1.0446","url":null,"abstract":"The cutting-edge upward push of artificial intelligence and system mastering has been of considerable size. It has reduced the human workload move forward exceptional of life exceptionally. This article describes using artificial intelligence and system learning to augment drug discovery and upgrade to lead them to more well organised and correct. In medication, specialties in which images are vitally important, like radiology, pathology or oncology, have seized the able to be done and full-size efforts in studies and development were deployed to switch the adaptness of AI to scientific packages. With AI becoming a extra widespread device for usual scientific imaging evaluation duties, together with prognosis, segmentation, or classification, the important thing for a secure and efficient use of medical AI packages. This body of work supported the jobs of system gaining knowledge of and synthetic intelligence in facilitating drug expansion and finding out methods, making them greater cost-powerful or altogether casting off the want for clinical trials, as a result of the potential to conduct simulations the usage of those technologies. Doing so will assist in separating wish from hype and lead to knowledgeable choice making at the top-quality use of AI/ML in drug development. Machine studying strategies can subterfuge complicated analyzes with huge, heterogeneous, and excessive dimensional information collections without a guide enter, which has proved helpful inside the writing commercial enterprise applications. Combining system mastering, particularly deep getting to know, with human skill and revel in is probably the great manner to coordinate numerous significant facts stores. The magnificent facts-mining capacity of AI innovation has given new essentiality to computer supported medication plans that incorporate more than one clinical concerns are higher than piecemeal data.","PeriodicalId":12808,"journal":{"name":"GSC Biological and Pharmaceutical Sciences","volume":"2 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of this study is to valorize yam spent grain obtained after extraction of starch in biscuit production. After extracting the starch from three varieties (Bakor, Kponan and Lokpa) of Dioscorea cayenensis-rotundata, the spent grains were dried at 45°C for 48 h then crushed and the flours were incorporated into the wheat (Triticum aestivum) flour at 5 and 10%. The physicochemical and functional properties of formulated flours were determined as well as the sensory characteristics of the biscuits produced. The results of the physicochemical properties of the formulations reveal moisture, fiber and carbohydrate levels varying respectively from 11.82±0.04 to 11.99±0.0; 1.84±0.01 to 2.35±0.03 and from 76.71±0.02 to 76.88±0.06. The formulated flours have appreciable functional properties in terms of water absorption capacity (83.32±0.32 - 87.78±0.40 g), water absorption capacity (126.29± 0.48 – 148.73±0.58 g) and inflation capacity (8.83±0.12 – 10.64±0.23 g). On the sensory level, the results showed that biscuits produced with 5% incorporation are the most appreciated. In order to contribute to food security, yam spent flours can be incorporated at a rate of 5%, thereby reducing wheat flour by 5%.
{"title":"Sensory evaluation of biscuits resulting from partial substitution of wheat flour with spent grain from three varieties (Bakor, Kponan and Lokpa) of Dioscorea cayenensis-rotundata complex cultivated in Brobo (Centern, Ivory Coast)","authors":"Armel Fabrice ZORO, Kouamé Appolinaire KOUASSI, Michel Archange LIBRA, Abdoulaye TOURE","doi":"10.30574/gscbps.2024.26.1.0507","DOIUrl":"https://doi.org/10.30574/gscbps.2024.26.1.0507","url":null,"abstract":"The aim of this study is to valorize yam spent grain obtained after extraction of starch in biscuit production. After extracting the starch from three varieties (Bakor, Kponan and Lokpa) of Dioscorea cayenensis-rotundata, the spent grains were dried at 45°C for 48 h then crushed and the flours were incorporated into the wheat (Triticum aestivum) flour at 5 and 10%. The physicochemical and functional properties of formulated flours were determined as well as the sensory characteristics of the biscuits produced. The results of the physicochemical properties of the formulations reveal moisture, fiber and carbohydrate levels varying respectively from 11.82±0.04 to 11.99±0.0; 1.84±0.01 to 2.35±0.03 and from 76.71±0.02 to 76.88±0.06. The formulated flours have appreciable functional properties in terms of water absorption capacity (83.32±0.32 - 87.78±0.40 g), water absorption capacity (126.29± 0.48 – 148.73±0.58 g) and inflation capacity (8.83±0.12 – 10.64±0.23 g). On the sensory level, the results showed that biscuits produced with 5% incorporation are the most appreciated. In order to contribute to food security, yam spent flours can be incorporated at a rate of 5%, thereby reducing wheat flour by 5%.","PeriodicalId":12808,"journal":{"name":"GSC Biological and Pharmaceutical Sciences","volume":"12 50","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-30DOI: 10.30574/gscbps.2024.26.1.0548
Hichem NAAS, Hamza BENBACHIR, Sarra MEHENNAOUI, Fatima Zohra HADJADJ-AOUL
Chemotherapy has an important role in the treatment of childhood cancers and contributes largely to current therapeutic successes. However, short- and long-term toxicity must be considered. This is why it is fundamental to understand the specificities related to the pediatric field.
{"title":"Cytotoxic agents and pediatric particularity","authors":"Hichem NAAS, Hamza BENBACHIR, Sarra MEHENNAOUI, Fatima Zohra HADJADJ-AOUL","doi":"10.30574/gscbps.2024.26.1.0548","DOIUrl":"https://doi.org/10.30574/gscbps.2024.26.1.0548","url":null,"abstract":"Chemotherapy has an important role in the treatment of childhood cancers and contributes largely to current therapeutic successes. However, short- and long-term toxicity must be considered. This is why it is fundamental to understand the specificities related to the pediatric field.","PeriodicalId":12808,"journal":{"name":"GSC Biological and Pharmaceutical Sciences","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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