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Development of Discriminant Model for Classifying Sprinters and Throwers on the Basis of Anthropometric and Physical Fitness Variables 基于人体测量和体质变量的短跑运动员和投掷运动员分类判别模型的建立
Pub Date : 2023-06-30 DOI: 10.55544/jrasb.2.3.24
Upendra Patidar, V. Saxena
In the present study, 100 athletes who competed at the state level was constitute up the sample; only male athletes from Madhya Pradesh in the senior category was included. During the morning and evening sessions, the necessary information on the subject was gathered using the random sampling method. before the National camps and practicing at TT Nagar Stadium Bhopal. The data were collected on anthropometric variables i.e. height, weight, sitting height, (leg, arm, hand) length, shoulder width, (chest, hip, thigh, calf) circumference, (back, shoulder, grip and leg explosive) strength. The anthropometric variables were measured by using selected standardized instruments and measuring tapes. Data collected was analysed at 0.05 level of significance, descriptive statistics and multiple discriminant analysis was applied to classify and predict group membership of the throwers into the sprinters and Throwers. The results showed that 100.0% of original grouped cases were correctly classified.
在本研究中,100名参加过国家级比赛的运动员组成了样本;只有中央邦的男性运动员参加了高级比赛。在上午和晚上的会议期间,使用随机抽样方法收集了有关该主题的必要信息。在国家训练营和TT纳加尔体育场博帕尔训练之前。数据收集于人体测量变量,即身高、体重、坐高、(腿、手臂、手)长度、肩宽、(胸、臀、大腿、小腿)周长、(背部、肩膀、握力和腿部爆发力)力量。采用选定的标准化仪器和卷尺测量人体测量变量。收集的数据在0.05显著性水平上进行分析,采用描述性统计和多重判别分析对投掷运动员分为短跑运动员和投掷运动员两类进行分类和预测。结果表明,100%的原始分组病例被正确分类。
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引用次数: 0
Recent Approaches of Intranasal to Brain Drug Delivery System 鼻内经脑给药系统的最新研究进展
Pub Date : 2023-06-30 DOI: 10.55544/jrasb.2.3.23
Sharad Bajpai, Y. Bajpai, Abhishek Awasthi, Chavi Mittal, Kanchan Tariyal, Prachi Sood, Roshan Kumar
While the intranasal administration of drugs to the brain has been gaining both research attention and regulatory success over the past several years, key fundamental and translational challenges remain to fully leveraging the promise of this drug delivery pathway for improving the treatment of various neurological and psychiatric illnesses. In response, this review highlights the current state of understanding of the nose-to-brain drug delivery pathway and how both biological and clinical barriers to drug transport using the pathway can been addressed, as illustrated by demonstrations of how currently approved intranasal sprays leverage these pathways to enable the design of successful therapies. Moving forward, aiming to better exploit the understanding of this fundamental pathway, we also outline the development of nanoparticle systems that show improvement in delivering approved drugs to the brain and how engineered nanoparticle formulations could aid in breakthroughs in terms of delivering emerging drugs and therapeutics while avoiding systemic adverse effects.
虽然在过去的几年中,鼻内给药大脑已经获得了研究关注和监管成功,但关键的基础和转化挑战仍然存在,即充分利用这种药物传递途径来改善各种神经和精神疾病的治疗。作为回应,本综述强调了目前对鼻到脑药物传递途径的理解状况,以及如何解决利用该途径进行药物运输的生物学和临床障碍,如目前批准的鼻内喷雾剂如何利用这些途径来实现成功治疗设计的演示所示。展望未来,为了更好地利用对这一基本途径的理解,我们还概述了纳米颗粒系统的发展,这些系统在向大脑输送经批准的药物方面表现出了改善,以及工程纳米颗粒配方如何有助于在输送新兴药物和治疗方法方面取得突破,同时避免全身不良反应。
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引用次数: 0
Microplastics in Drinking Water: Assessing Occurrence and Potential Risks 饮用水中的微塑料:评估发生和潜在风险
Pub Date : 2023-06-30 DOI: 10.55544/jrasb.2.3.25
Paresh Kumar, Yagya Sharma, Sameer Singh, Surabhi Sharma
Microplastics, small plastic particles measuring less than 5 millimeters, have emerged as a significant environmental concern due to their widespread presence in freshwater sources, including drinking water. This review paper aims to assess the occurrence of microplastics in drinking water and evaluate their potential risks to human health. The study employs a comprehensive approach to investigate microplastic contamination in drinking water sources, encompassing surface water bodies (such as rivers, lakes, and reservoirs) and groundwater reservoirs. This review underscores the urgent need for further research to enhance our understanding of microplastics' fate, transport, and potential health impacts on drinking water. It emphasizes the importance of standardized sampling and analytical techniques to facilitate accurate comparisons across studies. Furthermore, it emphasizes the necessity of implementing effective strategies to reduce and prevent microplastic pollution at its source, thereby ensuring safe and clean drinking water to populations globally.
微塑料是一种直径小于5毫米的小塑料颗粒,由于广泛存在于包括饮用水在内的淡水资源中,已成为一个重大的环境问题。本文旨在评估饮用水中微塑料的发生情况,并评估其对人体健康的潜在风险。该研究采用综合方法调查饮用水源中的微塑料污染,包括地表水(如河流、湖泊和水库)和地下水水库。这一综述强调了进一步研究的迫切需要,以提高我们对微塑料的命运、运输以及对饮用水的潜在健康影响的理解。它强调了标准化采样和分析技术的重要性,以促进研究之间的准确比较。此外,它强调必须实施有效战略,从源头上减少和预防微塑料污染,从而确保全球人口获得安全和清洁的饮用水。
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引用次数: 0
Review: How Vitamin D Supplementation Improve Insulin Sensitivity in Patients with Metabolic Syndrome 综述:补充维生素D如何改善代谢综合征患者的胰岛素敏感性
Pub Date : 2023-06-23 DOI: 10.55544/jrasb.2.3.21
Sami A. Zbaar
The metabolic syndrome is a group of cardio metabolic risk factors characterized by adipose tissue malfunction and insulin resistance. Insulin resistance might be one of the main reasons of many metabolic disturbances as well as dysregulation of the blood glucose level. In recent years, the relationship between vitamin D and insulin resistance has been a topic of debate and growing broad interest. In fact, vitamin D serum level may be one of the factors accelerating the development of insulin resistance. Vitamin D deficiency is a common abnormal condition in the population and may be involved with the pathogenesis of diseases related to insulin resistance, such as obesity, diabetes, hyperlipidemia and polycystic ovary syndrome (PCOS). In addition, there are several researches that recommended the use of vitamin D to improve insulin resistance in patients with metabolic disorders, but the mechanism by which the vitamin works to produce this effect is still a matter of debate among researchers. the aim of this review is to summarize the recent evidence suggest mechanisms by which vitamin D can improves insulin sensitivity.
代谢综合征是一组以脂肪组织功能障碍和胰岛素抵抗为特征的心脏代谢危险因素。胰岛素抵抗可能是许多代谢紊乱和血糖水平失调的主要原因之一。近年来,维生素D与胰岛素抵抗之间的关系一直是争论的话题,并引起了广泛的兴趣。事实上,血清维生素D水平可能是加速胰岛素抵抗发展的因素之一。维生素D缺乏是人群中常见的异常状况,可能与胰岛素抵抗相关疾病的发病机制有关,如肥胖、糖尿病、高脂血症和多囊卵巢综合征(PCOS)。此外,有几项研究建议使用维生素D来改善代谢紊乱患者的胰岛素抵抗,但维生素产生这种效果的机制在研究人员之间仍然存在争议。这篇综述的目的是总结最近的证据表明维生素D可以改善胰岛素敏感性的机制。
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引用次数: 0
Analytical Solution of Biological Population of Fractional Differential Equations by Reconstruction of Variational Iteration Method 用变分迭代法重构分数阶微分方程生物种群的解析解
Pub Date : 2023-06-23 DOI: 10.55544/jrasb.2.3.20
Mohammad Ali Zirak, A. Poya
This article presents a brand-new approximation analytical technique we refer to as the reconstruction of variational iteration method. For the goal of solving fractional biological population option pricing equations, this methodology was created. In certain circumstances, you may actually use the well-known Mittag-Leffer function to get an explicit response. The usage of the three examples below demonstrates the precision and effectiveness of the suggested method. The results show that the RVIM is not only quite straightforward but also very successful at resolving non-linear problems.
本文提出了一种全新的近似分析技术,我们称之为变分迭代法的重构。为求解分数生物种群期权定价方程,建立了该方法。在某些情况下,您实际上可以使用著名的mittag - letter函数来获得显式响应。下面三个例子的使用证明了所建议方法的准确性和有效性。结果表明,RVIM不仅非常简单,而且在解决非线性问题方面非常成功。
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引用次数: 0
A Review Article: Hypersensitivity and its Disorders 综述:超敏反应及其疾病
Pub Date : 2023-06-23 DOI: 10.55544/jrasb.2.3.22
May Y. Al-Ma'amouri
Hypersensitivity reactions are a set of reactions in which the immune system performs a protective function while also producing an inflammatory consequence. In most cases, both autoimmunity and sensitivities have been responsible for hypersensitivity reactions. In autoimmune contagion, the immune system reacts directly to tissues inside the body, while in sensitivities, the immune system reacts to parts of the environment that are shared. In general, allergic reactions have been put into four groups (Type I, Type II, Type III, and Type IV). This study focuses on hypersensitivity-related illnesses and the role of the immune system in these conditions.
超敏反应是免疫系统在发挥保护作用的同时也产生炎症后果的一系列反应。在大多数情况下,自身免疫和敏感性都是超敏反应的原因。在自身免疫感染中,免疫系统直接对体内组织起反应,而在敏感性中,免疫系统对共享环境的部分起反应。一般来说,过敏反应被分为四组(I型,II型,III型和IV型)。本研究的重点是过敏相关疾病和免疫系统在这些情况下的作用。
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引用次数: 0
Clinical Features Present, Past & Future Prospective of Monkey Pox: A Orthopoxvirus 猴痘:一种正痘病毒的临床特征、过去和未来展望
Pub Date : 2023-06-21 DOI: 10.55544/jrasb.2.3.18
S. Shukla, Naveen Rawat, Sarthak Rana, Vinod Rana, Chavi Mittal, Roshan Kumar, Prachi Sood
Some issues regarding the potential spread of monkeypox have arisen just as the international world is beginning to recover from the initial alarm that was caused by the probable spread of coronavirus disease 2019 (COVID-19). Despite the fact that parts of Africa have traditionally been more susceptible to monkeypox than other regions of the world, the majority of new cases that have been linked to the outbreak that began in 2022 have been reported in countries located in Europe and the western hemisphere. Despite the fact that a great number of organisations are working on contact-tracing activities at the moment, the origin of this outbreak is still unknown at this time. The monkeypox virus belongs to the family of viruses known as Poxviridae and the genus known as Orthopoxvirus. Following the eradication of smallpox across the globe in the 1970s, news of monkeypox caused widespread worry across the globe. Through vaccination with the smallpox virus, individuals were able to develop cross-immunity against monkeypox. After distribution of the smallpox vaccine was discontinued, the number of outbreaks of monkeypox rose. The monkeypox epidemic that occurred in the United States in 2003 was the first time that the disease gained extensive notice in the media. In spite of its name, the virus known as monkeypox is not transmitted by monkeys. Although a number of different kinds of rodents and other small mammals have been suggested as the primal hosts of the monkeypox virus, the virus's true lineage is still a mystery. The virus that causes monkeypox was first identified in macaque monkeys, which is where the disease was first seen. When monkeypox does transfer from one person to another, it often does so through a person's mucocutaneous lesions or through the respiratory droplets that they expel. However, this only happens very infrequently. However, supporting therapy can be given to reduce symptoms, and medications such tecovirimat may be administered in really severe cases. At this time, there is no specific treatment for patients who have infected the virus; however, supportive treatments can be given. It is debatable whether or not these treatments are successful in reducing symptoms because there are no concrete guidelines to follow in this regard.
就在国际社会开始从2019年冠状病毒病(COVID-19)可能传播引起的最初警报中恢复过来之际,出现了一些关于猴痘潜在传播的问题。尽管非洲部分地区传统上比世界其他地区更容易感染猴痘,但与2022年开始的疫情有关的大多数新病例报告发生在欧洲和西半球国家。尽管许多组织目前正在开展接触者追踪活动,但目前仍不清楚这次疫情的起源。猴痘病毒属于痘病毒科和正痘病毒属。继20世纪70年代在全球消灭天花之后,猴痘的消息在全球引起了广泛的担忧。通过接种天花病毒,个体能够对猴痘产生交叉免疫。在停止分发天花疫苗后,猴痘暴发的次数有所上升。2003年在美国发生的猴痘疫情是这种疾病第一次在媒体上得到广泛关注。尽管名为猴痘,但这种病毒并不是由猴子传播的。尽管许多不同种类的啮齿动物和其他小型哺乳动物被认为是猴痘病毒的原始宿主,但该病毒的真正谱系仍然是一个谜。引起猴痘的病毒最初是在猕猴身上发现的,这也是这种疾病首次被发现的地方。当猴痘确实从一个人传播到另一个人时,它通常是通过一个人的皮肤粘膜病变或通过他们排出的呼吸道飞沫传播的。然而,这种情况很少发生。然而,可以给予辅助治疗以减轻症状,并且在非常严重的病例中可以使用诸如替柯维明之类的药物。此时,对感染病毒的患者没有特异性治疗;然而,可以给予支持性治疗。这些治疗是否能成功减轻症状是有争议的,因为在这方面没有具体的指导方针可循。
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引用次数: 2
Review on: Pharmacological Activity of Caterpilllar fungus (Keeda Jadi) 毛虫真菌的药理活性研究进展
Pub Date : 2023-06-20 DOI: 10.55544/jrasb.2.3.17
Bhavesh Bharti, M. Chaudhary, Dr. Vinod Rana, Salman Ahmad, Neha Tamta, Kriti Dabral, Yashika Uniyal
In this review we focus about the pharmacology, biological characteristics and therapeutic uses of Caterpillar fungus (Keeda jari) which is also known as keeda ghaas, Yarsa gamba. It is found at high Himalayan mountains of India, Nepal and Tibet. It is found between 350 and 5000 meters above sea level. It is an entomo-fungal combination of a larva of small moth, Hepialus armoricanus and a parasite fungus Cordyceps sinensis. Cordyceps is best known medicine for increasing physical stamina and sexual functions. It has been proven to improve liver, kidney, and lung functioning in addition to being routinely used to treat people with heart disease. Numerous investigations have shown that it possesses a wide range of biological functions and pharmacological potential despite not being harvested in a sustainable or deliberate manner.
本文就冬虫夏草(又称冬虫夏草、冬虫夏草)的药理、生物学特性及治疗用途作一综述。它被发现在印度、尼泊尔和西藏的高喜马拉雅山脉。它位于海拔350至5000米之间。它是由一种小蛾的幼虫和一种寄生真菌冬虫夏草结合而成的昆虫真菌。冬虫夏草是最著名的增强体力和性功能的药物。除了常规用于治疗心脏病患者外,它还被证明可以改善肝、肾和肺功能。许多研究表明,尽管没有以可持续或故意的方式收获,但它具有广泛的生物学功能和药理潜力。
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引用次数: 0
Lecturers' Perception of Deans’ Ethical Leadership and its Impact on Lecturers’ Engagement at Public Universities in Afghanistan 阿富汗公立大学讲师对院长道德领导的看法及其对讲师参与的影响
Pub Date : 2023-06-20 DOI: 10.55544/jrasb.2.3.16
Faridullah Salarzai, Ghulam Omer Abdullah
This study found out lecturers’ perception of deans’ ethical leadership and its relationship with lecturers’ engagement at public universities in Afghanistan. The study used a quantitative method and correlational research design. The data was collected from 152 respondents from ten public universities through an electronic questionnaire. The study used descriptive statistics to obtain the deans’ ethical leadership perception and inferential statistics to determine the correlation between the variables. The result of the study showed that deans of the faculties at public universities in Afghanistan are moderate ethical leaders, and has a significant relationship with instructors' emotional engagement and social engagement (colleagues) and no significant relationship with cognitive engagement and social engagement (students).
本研究发现阿富汗公立大学讲师对院长道德领导的看法及其与讲师参与的关系。本研究采用定量方法和相关研究设计。这些数据是通过电子问卷从10所公立大学的152名受访者中收集的。本研究使用描述性统计获得院长伦理领导感知,并使用推论统计来确定变量之间的相关性。研究结果表明,阿富汗公立大学院长是温和的伦理领导者,与教师的情感投入和社会投入(同事)有显著的关系,与认知投入和社会投入(学生)没有显著的关系。
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引用次数: 1
Role of Essential Oil Used Pharmaceutical Cosmetic Product 药用化妆品中精油的作用
Pub Date : 2023-06-19 DOI: 10.55544/jrasb.2.3.19
Atul Sharma, Vinay V. Kumar, Chavi Mittal, Vinod Rana, Kriti Dabral, Gulafshan Parveen
When it comes to choosing which cosmetics to buy, consumers typically identify the smell as the factor that is most important to them. When uncovered, the fatty acids, oils, and surfactants that are frequently included in cosmetic formulations can all contribute to the production of odours that are unpleasant. Essential oils are used in a wide variety of cosmetic products because, in addition to the fragrant contributions they make, they serve as preservatives, active agents, and additions that are helpful to the skin. In addition, the growing demand for natural components has significantly contributed to the revival of interest in plant derivatives, particularly essential oils, in the industries of cosmetics and health. Popular cosmetic companies have been forced to promote natural fragrances and pick for minimally processed natural materials as a result of the potential health concerns related with artificial smell compounds, which are major components of cosmetics. As a result of this pressure, the cosmetic industry as a whole has moved towards natural fragrances. Some of the most highly regarded essential oils that are utilised in the creation of fragrances include citrus, lavender, eucalyptus, tea tree, and other flower oils. Some of the most highly prized scent components that are utilised in the creation of various cosmetics include linalool, geraniol, limonene, citronellol, and citral. In the fields of cosmetics and cosmeceuticals, essential oils have a wide variety of applications, including use as a source of natural fragrances. The purpose of this review was to shed light on those applications. Origins of essential oils, commercial viability of essential oils, chemical makeup of essential oils, fragrance classification, olfactory character of essential oils, authenticity, and safety will all receive the attention they deserve.
在选择购买哪种化妆品时,消费者通常认为气味对他们来说是最重要的因素。化妆品配方中经常包含的脂肪酸、油脂和表面活性剂一旦被揭开,就会产生令人不快的气味。精油被广泛用于各种各样的化妆品中,因为除了它们的芳香贡献外,它们还可以作为防腐剂、活性剂和对皮肤有益的添加剂。此外,对天然成分日益增长的需求大大促进了对化妆品和保健工业中植物衍生物,特别是精油的兴趣的恢复。受欢迎的化妆品公司被迫推广天然香水,并选择加工程度最低的天然材料,因为人工气味化合物是化妆品的主要成分,可能会引起健康问题。由于这种压力,整个化妆品行业都转向了天然香水。一些最受推崇的精油被用于制造香水,包括柑橘、薰衣草、桉树、茶树和其他花油。用于制造各种化妆品的一些最珍贵的气味成分包括芳樟醇、香叶醇、柠檬烯、香茅醛和柠檬醛。在化妆品和药妆品领域,精油有各种各样的应用,包括用作天然香味的来源。这次审查的目的是阐明这些应用。精油的来源,精油的商业可行性,精油的化学组成,香味分类,精油的嗅觉特性,真实性和安全性都将得到应有的关注。
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引用次数: 0
期刊
International Journal For Research in Applied Sciences and Biotechnology
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