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Herbs Having Analgesic Activity 具有镇痛作用的草药
Pub Date : 2023-10-03 DOI: 10.55544/jrasb.2.5.1
Pallabi Saha, Debajyoti Biswas, Prodip Roy, Mrityunjoy Majumdar, Sourav Roy, Ruchismita Manna, Arpan Chanda, Suranjanaa Das, Mainak Mukherjee, Shaon Dey, Debapriya Das
Healthcare maintains a high priority on pain management, and research to develop safer and more potent analgesics is ongoing. Natural goods, especially plants, have recently attracted renewed interest as potential sources of analgesic medications. In this study, various techniques are used to measure pain. The rich source of analgesics found in medicinal plants includes Moringa oleifera, Aloe barbadensis, Curcuma longa, Eugenia caryophyllata, Adhatoda vasica, Mentha piperita, Ocimum sanctum, Zingiber officinale, Lavandula angustifolia, Epilobium angustifolium, Dialium guineense, Sida acuta, Stylosanthes fruticose, Bougainvilla spectabilis, Ficus glomerata, Polyalithia longifolia, Calotropis gigantea, Tinospora cordifolia, Ageratina glabrata, Mangifera indica, Peperomia pellucida, Jatropha gossypifolia, Leonotis leonurus, Mimosa rubicaulis, Cussonia paniculate, Biebersteinia multifida, Alternanthera sessislis, Mentha arvensis, Oroxylum indicum, Tamarindus indica, Cucurbita maxima, Cucumis sativus, Emblica officinalis, Angiopteris evecta, Parastrephia lephidophylla, Peperomia pellucida, Scoparia dulcis, Ficus racemose, Eremostachys laciniata, Phlogacanthus thyrsiflorus, Kigelia pinnata, Molineria capitulate, Manihot esculenta, Ficus religiosa, Dalbergia sissoo, Grangea maderaspatana, Nothospondias staudtii, Rhodiola rosea, Juniperus communis, Erythrina variegate etc. The results reported in this review paper represent scientific knowledge that may be applied in the future to isolate potentially active molecules from some of these medicinal plants.
医疗保健对疼痛管理保持高度重视,开发更安全和更有效的镇痛药的研究正在进行中。天然产品,特别是植物,最近作为镇痛药物的潜在来源引起了人们的新兴趣。在这项研究中,使用了各种技术来测量疼痛。药用植物中镇痛药的丰富来源包括辣木、芦荟、姜黄、山竹、薄荷、麝香、山竹、生姜、薰衣草、紫菀、豚草、尖叶、茎花、九重葛、无花果、长叶蓼、大茶花树、花青树、光叶ageratia、芒果、Peperomia pellucida、麻疯树gossypifolia, Leonotis益母草,含羞草rubicaulis, Cussonia有圆锥花序的,Biebersteinia multifida,其中sessislis,各种薄荷,Oroxylum indicum, Tamarindus籼稻,Cucurbita最大值,Cucumis巨大,兰,运用evecta, Parastrephia lephidophylla,豆瓣绿属,Scoparia dulcis,榕树总状花序的,Eremostachys laciniata, Phlogacanthus thyrsiflorus, Kigelia pinnata, Molineria投降,木薯耐糖,榕树宗教性,Dalbergia sissoo,大苍子、石竹、红景天、杜松、赤藓等。本文的研究结果为今后从这些药用植物中分离潜在活性分子提供了科学依据。
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引用次数: 0
Isolation and Diagnosis of Escherichia coli bacteria from Patients with Urinary Tract Infections and Bacteriosis and Studying their Sensitivity to Some Antibiotics and Nanobodies 尿路感染和细菌病患者中大肠杆菌的分离诊断及其对抗生素和纳米体的敏感性研究
Pub Date : 2023-09-28 DOI: 10.55544/jrasb.2.4.27
Rania Maged Hamad, Yassien Hussain Owaied Al-Juboory, Iman Tajer Abdullah
The current study included the collection of 120 clinical samples (diuresis, blood) from patients visiting Baghdad city hospitals (Yarmouk Teaching Hospital, Central Children's Teaching Hospital, and Baghdad Teaching Hospital) for the period from November 2022 to February 2023. 30 discharge samples were collected from healthy people as a control group. The samples were within different ages and genders ranging from 14 years to 52 years. 10% of the E bacteria have been isolated coli of blood and 150% of blood based on phenotypic and culture characteristics and biochemical tests and the diagnosis was confirmed using the phytic device. The results of the sensitivity test of bacterial isolates using the tablet method of diffusion showed that most of the isolates were resistant to the antibiotics used, where the percentage of resistance to Tetracycline (96%), (84%) Nitrofurantoin, (82%) Ceftriaxone, (66%) Meropenem, (52%) Ciprofloaxcine, (70%) Gentamicin, (80%) Amikacin, (46%) Imipenem, Nalidixic acid (40%). The antimicrobial activity of gold and titanium nanoparticles was evaluated against 15 bacterial isolates (5 isolated from diuretic samples, 5 exit samples, 5 blood samples) using the diffusion method by gratigran. The results showed that the nanoparticles had a clear inhibitory effect against the studied isolates where the average inhibition diameters ranged between 17-22 mm and the MIC value (Minimal inhibitory concentration) was between 64-126.
目前的研究包括从2022年11月至2023年2月期间在巴格达市医院(耶尔穆克教学医院、中央儿童教学医院和巴格达教学医院)就诊的患者收集120份临床样本(利尿、血液)。选取健康人群出院标本30份作为对照组。这些样本的年龄和性别从14岁到52岁不等。根据表型和培养特征及生化试验,分离出10%的大肠杆菌和150%的血液,并使用植体装置确诊。 采用片剂扩散法对分离菌进行敏感性试验,结果显示大部分分离菌对所使用的抗生素均有耐药,其中对四环素(96%)、呋喃妥英(84%)、头孢曲松(82%)、美罗培南(66%)、环丙沙星(52%)、庆大霉素(70%)、阿米卡星(80%)、亚胺培南(46%)、萘啶酸(40%)耐药;采用栅格扩散法对15株细菌(利尿剂样品5株、出口样品5株、血液样品5株)进行抑菌活性评价。结果表明,纳米颗粒对所研究的菌株具有明显的抑制作用,平均抑制直径为17 ~ 22 mm,最小抑制浓度(MIC)为64 ~ 126。
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 The results of the sensitivity test of bacterial isolates using the tablet method of diffusion showed that most of the isolates were resistant to the antibiotics used, where the percentage of resistance to Tetracycline (96%), (84%) Nitrofurantoin, (82%) Ceftriaxone, (66%) Meropenem, (52%) Ciprofloaxcine, (70%) Gentamicin, (80%) Amikacin, (46%) Imipenem, Nalidixic acid (40%).
 The antimicrobial activity of gold and titanium nanoparticles was evaluated against 15 bacterial isolates (5 isolated from diuretic samples, 5 exit samples, 5 blood samples) using the diffusion method by gratigran. The results showed that the nanoparticles had a clear inhibitory effect against the studied isolates where the average inhibition diameters ranged between 17-22 mm and the MIC value (Minimal inhibitory concentration) was between 64-126.","PeriodicalId":13755,"journal":{"name":"International Journal For Research in Applied Sciences and Biotechnology","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135470099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Estimation of Underground Economy in Afghanistan Using Mathematical Fuzzy Model Based on Mean and Standard Deviation 基于均值和标准差的模糊数学模型估算阿富汗地下经济
Pub Date : 2023-09-25 DOI: 10.55544/jrasb.2.4.25
Wali Mohammad Azizi, Athiqullah Hayat, Shamsullah Shams, Mohammad Izat Emir Zulkifly
The underground economy (UE) briefly comprises services, activities, and transactions, which could be legal or illegal. In this paper the size of UE is estimated through mathematical fuzzy model based on fuzzy set, fuzzy logic and constructed a yearly time-series for UE over the period 2001 to 2020 in Afghanistan. Two input variables are used; unemployment rate (UR) and the government regulations (REG). Fuzzification, fuzzy inference and defuzzification; the three steps that are considered for estimating UE in the country, based on mean and standard deviation (SD) for each variable individually. The result indicates four cycles for time series and shows that people were more involved in UE activities over the first and third cycles and less involved over the second and fourth cycles.
地下经济(UE)简单地包括服务、活动和交易,可能是合法的,也可能是非法的。本文采用基于模糊集、模糊逻辑的模糊数学模型估计了阿富汗2001 - 2020年的利用效率规模,并构建了阿富汗2001 - 2020年的利用效率年度时间序列。使用两个输入变量;失业率(UR)和政府法规(REG)。模糊化、模糊推理和去模糊化;根据每个变量的平均值和标准差(SD),考虑估算该国UE的三个步骤。结果表明时间序列有四个周期,并且表明人们在第一个和第三个周期中更多地参与UE活动,而在第二个和第四个周期中参与较少。
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引用次数: 0
Dairy Cows Transition Period Feeding and Management 奶牛过渡期饲养与管理
Pub Date : 2023-09-25 DOI: 10.55544/jrasb.2.4.26
Sayed Rahimullah Mushfiq, Mohammad Hassan Aabidy, Rizwanullah Rafed
Proper feeding during the pregnancy and post-pregnancy period, determines the milk Production, ensuing lactation and as well as, the reproductive efficiency of the animal. 3 weeks before and 3 weeks after parturition are very important because a dramatic physiological and metabolic adaptation occurs during this period which is called the transition period. The Nutritional imbalances are caused by the low quality of desired nutritious rations, reduced appetite, and low ingestion which are responsible for depressed performance, specifically during the transition period. The absence of knowledge and skills of farmers in feeding management during the transition period exacerbates the situation. The metabolic changes, metabolic adaptations, Mechanism of a Transition period, transition period feeding management to prevent disorder, Decreased dry matter intake (DMI), Nutrient requirements, Infectious diseases and metabolic disorders, Nutritional management to Ease out the Transition Period, Management of the transition period, Feed additives supplementation and nutritional-management strategies to passage transition period are discussed by this review paper. Simultaneously, with the growth of the fetus, the nutrient requirements increase and are at their peak before parturition as well as immediately after parturition. The peak milk production reaches about 5–8 weeks postpartum, while the diet consumption peaks at 10–14 weeks postpartum. So, dairy cows will typically suffer a 6–8-week period of negative energy balance during the postpartum period. The requirement energy of the mammary at 4 days postpartum is more than three times than that of the uterus, with a simultaneous increase in the requirement of metabolizable protein, especially of methionine and lysine. The high metabolic incidence of infectious diseases is responsible for the high incidence of inflammatory conditions, mostly immediately after calving. To prevent mentioned diseases, pro-inflammatory cytokine release should be avoided postpartum. The body reserves mobilization, especially fat and protein; and hepatic gluconeogenesis takes place immediately after parturition leading to increased levels of β-hydroxy butyric acid and non-esterified fatty acids, which act as a gateway for several metabolic diseases. The phase of transition may eased by increasing DMI, feed conversion efficiency, density of ration, and protein supplements rich in rumen un-degradable protein; by using anionic mineral mixture, optimizing roughage to concentrate (R: C) ratio, optimum physically effective fiber length of forages/silage/hay, dietary buffers, feed additives such as inflammation modulators, protected nutrients, glucogenic precursors and direct-fed microbial/probiotics.
在怀孕期间和怀孕后的适当喂养,决定了动物的产奶量、随后的泌乳以及繁殖效率。产前3周和产后3周是非常重要的,因为在这段时间里会发生剧烈的生理和代谢适应,也就是所谓的过渡期。营养不平衡是由于所需营养口粮质量低、食欲下降和摄取量低造成的,这些都是导致表现低迷的原因,特别是在过渡时期。在过渡时期,农民缺乏饲养管理知识和技能使情况更加恶化。本文就过渡时期的代谢变化、代谢适应、过渡时期的机制、过渡时期饲养管理预防失调、干物质采食量减少、营养需要量、传染性疾病与代谢失调、缓解过渡时期的营养管理、过渡时期的管理、饲料添加剂的添加以及过渡时期的营养管理策略进行了综述。同时,随着胎儿的生长发育,对营养物质的需要量也随之增加,在产前和产后均达到高峰。产奶高峰在产后5-8周左右,饮食消耗高峰在产后10-14周。因此,奶牛在产后通常会经历6 - 8周的负能量平衡期。产后4天乳腺需要量是子宫需要量的3倍以上,同时代谢蛋白需要量增加,尤其是蛋氨酸和赖氨酸的需要量增加。传染性疾病的高代谢发病率是造成炎症的高发病率的原因,大多数是在产犊后立即发生的。为预防上述疾病,应避免产后释放促炎细胞因子。身体储备动员,尤其是脂肪和蛋白质;分娩后立即发生肝脏糖异生,导致β-羟基丁酸和非酯化脂肪酸水平升高,这是几种代谢性疾病的门户。提高DMI、饲料转化率、日粮密度和添加富含瘤胃不可降解蛋白的蛋白质可缓解过渡阶段;通过使用阴离子矿物混合物、优化粗精料比(R: C)、优化饲料/青贮/干草物理有效纤维长度、饲粮缓冲料、饲料添加剂(如炎症调节剂、保护性营养素、糖原体和直饲微生物/益生菌)。
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引用次数: 0
Current Management of Hepatic Encephalopathy: A Review Article 当前肝性脑病的管理:综述文章
Pub Date : 2023-09-23 DOI: 10.55544/jrasb.2.4.24
Jaya Ghosh, Jhumur Ghosh
Hepatic encephalopathy, a neuropsychiatric syndrome stemming from liver failure, manifests in acute and chronic cases. The prevailing cause behind its development involves the neurotoxicity resulting from elevated ammonia levels in the brain, which can occur due to increased ammonia production or impaired ammonia excretion. The main objective in treating hepatic encephalopathy is to decrease ammonia levels. The detoxification of ammonia in this condition is regulated by two enzymes: glutaminase and glutamine synthetase. Numerous drugs, such as lactulose, rifaximin, BCAA, LOLA, glycerol phenylbutyrate, and zinc, have been utilized to treat hepatic encephalopathy. In terms of future research, experimental treatment options like fecal microbiota transplant, probiotics, bromocriptine, minocycline, indomethacin, ibuprofen, and flumazenil warrant investigation. Furthermore, albumin infusions have been shown to enhance cognitive function and improve the psychosocial quality of life, possibly by alleviating endothelial dysfunction in patients with minimal hepatic encephalopathy or previous episodes of hepatic encephalopathy. This review article offers a comprehensive overview of the current management strategies for hepatic encephalopathy.
肝性脑病是一种由肝功能衰竭引起的神经精神综合征,表现为急性和慢性病例。其发展背后的主要原因涉及大脑中氨水平升高导致的神经毒性,这可能是由于氨产生增加或氨排泄受损而发生的。治疗肝性脑病的主要目的是降低氨水平。在这种情况下,氨的解毒是由两种酶调节的:谷氨酰胺酶和谷氨酰胺合成酶。许多药物,如乳果糖、利福昔明、BCAA、LOLA、苯基丁酸甘油和锌,已被用于治疗肝性脑病。在未来的研究中,需要对粪便菌群移植、益生菌、溴隐亭、米诺环素、吲哚美辛、布洛芬和氟马西尼等实验性治疗方案进行研究。此外,白蛋白输注已被证明可以增强认知功能和改善生活的社会心理质量,可能是通过减轻轻度肝性脑病或既往肝性脑病发作患者的内皮功能障碍。本文综述了目前肝性脑病的治疗策略。
{"title":"Current Management of Hepatic Encephalopathy: A Review Article","authors":"Jaya Ghosh, Jhumur Ghosh","doi":"10.55544/jrasb.2.4.24","DOIUrl":"https://doi.org/10.55544/jrasb.2.4.24","url":null,"abstract":"Hepatic encephalopathy, a neuropsychiatric syndrome stemming from liver failure, manifests in acute and chronic cases. The prevailing cause behind its development involves the neurotoxicity resulting from elevated ammonia levels in the brain, which can occur due to increased ammonia production or impaired ammonia excretion. The main objective in treating hepatic encephalopathy is to decrease ammonia levels. The detoxification of ammonia in this condition is regulated by two enzymes: glutaminase and glutamine synthetase. Numerous drugs, such as lactulose, rifaximin, BCAA, LOLA, glycerol phenylbutyrate, and zinc, have been utilized to treat hepatic encephalopathy. In terms of future research, experimental treatment options like fecal microbiota transplant, probiotics, bromocriptine, minocycline, indomethacin, ibuprofen, and flumazenil warrant investigation. Furthermore, albumin infusions have been shown to enhance cognitive function and improve the psychosocial quality of life, possibly by alleviating endothelial dysfunction in patients with minimal hepatic encephalopathy or previous episodes of hepatic encephalopathy. This review article offers a comprehensive overview of the current management strategies for hepatic encephalopathy.","PeriodicalId":13755,"journal":{"name":"International Journal For Research in Applied Sciences and Biotechnology","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135966833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Impact of Employee Satisfaction on Organizational Success: Evidence from Private Sector Organizations in Khost, Afghanistan 探索员工满意度对组织成功的影响:来自阿富汗霍斯特私营部门组织的证据
Pub Date : 2023-09-20 DOI: 10.55544/jrasb.2.4.23
None Jahan, Faridullah Lalzai, Hafizullah Meen Amin
The primary objective of this research paper is to examine workplace employee satisfaction and its influence on the effective utilization of organizational resources. This entails exploring the various factors that significantly impact employee satisfaction within an organization, with the goal of identifying key drivers that have a profound effect on the morale and motivation of the workforce. By understanding these crucial factors, organizations can employ diverse strategies to enhance employee performance, thereby maximizing both individual and organizational objectives. In today's competitive market landscape, human resources are undeniably a critical asset for any organization. With intense competition, businesses are relentlessly striving to enhance customer satisfaction to gain a competitive edge. The utilization of human resources has a direct and substantial impact not only on customer satisfaction but also on gaining a competitive advantage. Consequently, it is imperative for managers to consistently assess employee satisfaction and pay close attention to the variables that exert significant influence on both employee satisfaction and performance. To investigate employee satisfaction and its ramifications on employee performance, this study employs a survey method. The utilization of an experimental approach is deemed unnecessary for this research, as employee satisfaction primarily involves theoretical aspects, making experimental methodologies redundant. Data for this research was collected through questionnaires, constituting primary data, targeting managers at various organizational levels within the private sector. The analysis of the gathered data reveals a robust positive correlation between employee satisfaction and employee performance. Notably, the variables most closely associated with employee satisfaction, and subsequently, with a significant impact on employee performance, are employee creativity and reduced absenteeism. Consequently, it can be confidently asserted that there exists a strong, positive relationship between employee satisfaction, employee performance, and the attainment of organizational goals.
本研究的主要目的是研究工作场所员工满意度及其对组织资源有效利用的影响。这需要探索影响组织内员工满意度的各种因素,目标是确定对员工士气和动机有深远影响的关键驱动因素。通过了解这些关键因素,组织可以采用不同的策略来提高员工绩效,从而最大化个人和组织的目标。 在当今竞争激烈的市场环境中,人力资源无疑是任何组织的关键资产。在激烈的竞争中,企业不断努力提高客户满意度,以获得竞争优势。人力资源的利用不仅对顾客满意度有直接和实质性的影响,而且对获得竞争优势也有直接和实质性的影响。因此,管理者必须始终如一地评估员工满意度,并密切关注对员工满意度和绩效都有重大影响的变量。为了调查员工满意度及其对员工绩效的影响,本研究采用了调查方法。由于员工满意度主要涉及理论方面,实验方法的使用被认为是不必要的,因此实验方法是多余的。本研究的数据是通过问卷收集的,构成原始数据,目标是私营部门内各个组织级别的管理人员。 对收集到的数据进行分析,发现员工满意度与员工绩效之间存在显著的正相关关系。值得注意的是,与员工满意度最密切相关的变量,随后对员工绩效产生重大影响,是员工创造力和减少缺勤。因此,可以自信地断言,在员工满意度、员工绩效和组织目标的实现之间存在着强烈的、积极的关系。
{"title":"Exploring the Impact of Employee Satisfaction on Organizational Success: Evidence from Private Sector Organizations in Khost, Afghanistan","authors":"None Jahan, Faridullah Lalzai, Hafizullah Meen Amin","doi":"10.55544/jrasb.2.4.23","DOIUrl":"https://doi.org/10.55544/jrasb.2.4.23","url":null,"abstract":"The primary objective of this research paper is to examine workplace employee satisfaction and its influence on the effective utilization of organizational resources. This entails exploring the various factors that significantly impact employee satisfaction within an organization, with the goal of identifying key drivers that have a profound effect on the morale and motivation of the workforce. By understanding these crucial factors, organizations can employ diverse strategies to enhance employee performance, thereby maximizing both individual and organizational objectives.
 In today's competitive market landscape, human resources are undeniably a critical asset for any organization. With intense competition, businesses are relentlessly striving to enhance customer satisfaction to gain a competitive edge. The utilization of human resources has a direct and substantial impact not only on customer satisfaction but also on gaining a competitive advantage. Consequently, it is imperative for managers to consistently assess employee satisfaction and pay close attention to the variables that exert significant influence on both employee satisfaction and performance. To investigate employee satisfaction and its ramifications on employee performance, this study employs a survey method. The utilization of an experimental approach is deemed unnecessary for this research, as employee satisfaction primarily involves theoretical aspects, making experimental methodologies redundant. Data for this research was collected through questionnaires, constituting primary data, targeting managers at various organizational levels within the private sector.
 The analysis of the gathered data reveals a robust positive correlation between employee satisfaction and employee performance. Notably, the variables most closely associated with employee satisfaction, and subsequently, with a significant impact on employee performance, are employee creativity and reduced absenteeism. Consequently, it can be confidently asserted that there exists a strong, positive relationship between employee satisfaction, employee performance, and the attainment of organizational goals.","PeriodicalId":13755,"journal":{"name":"International Journal For Research in Applied Sciences and Biotechnology","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136312854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review Article: Vitamin's D Physiologic Properties and Functions 综述文章:维生素D的生理特性和功能
Pub Date : 2023-09-18 DOI: 10.55544/jrasb.2.4.21
Lamiaa Saoud Abbod AL-anbagi, Rafah Oday Hussaein
When 7-dehydrocholesterol is exposed to ultraviolet light, a prohormone called In the skin D3 is created. Being biologically inert, it must first be changed into 25-hydroxyvitamin D. D3 must first be converted to 1,25-dihydroxyvitamin D3 in the kidney formerly usage. The 1,25-dihydroxyvitamin D3 hormone, which has an array of functions, interacts with a nuclear receptor, includes calcium concentration, intestinal phosphate concentration, and bone calcium mobilization, and kidney calcium reabsorption. There are numerous additional noncalcemic uses for it in the body. In this review, physiological, endocrinologic, and molecular biologic properties of vitamin D are briefly discussed.
当7-脱氢胆固醇暴露在紫外线下时,一种叫做皮肤D3的激素原就产生了。由于它具有生物惰性,必须首先转化为25-羟基维生素d。D3必须首先在肾脏中转化为1,25-二羟基维生素D3。1,25-二羟基维生素D3激素具有一系列功能,可与核受体相互作用,包括钙浓度、肠磷酸盐浓度、骨钙动员和肾钙重吸收。它在体内还有许多其他的非钙性用途。本文就维生素D的生理、内分泌和分子生物学特性作一综述。
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引用次数: 0
Review Article: Effect Anticancer Drug of Histological Alteration and Improvement their Effects by Natural Antioxidants 综述文章:抗肿瘤药物对组织改变的作用及天然抗氧化剂对其作用的改善
Pub Date : 2023-09-18 DOI: 10.55544/jrasb.2.4.22
Raghad Jawad Salman, Roaa M. H. Shoker, Hakim Bahlok Jebur
Usually, Cancer and anticancer drugs can produce harmful side effects, side effects which occur in tissues or organs and produce adverse histopathological change. Cancer treatment by radiotherapy and chemotherapy, and chemotherapy treatments is more mostly used all over the world. Generally, chemotherapy drugs cusses the damage by free radicals and produce cytotoxicity. Natural antioxidant compounds of daily diet are more effective to scavenge or neutralize the free radicals which create by chemotherapy drugs and finally, improvement histopathological change.
通常,癌症和抗癌药物会产生有害的副作用,这些副作用会发生在组织或器官中,并产生不良的组织病理改变。癌症的治疗方式主要有放疗和化疗,而化疗在世界范围内应用较多。一般来说,化疗药物会引起自由基的损伤并产生细胞毒性。日常饮食中的天然抗氧化化合物更有效地清除或中和化疗药物产生的自由基,最终改善组织病理变化。
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引用次数: 0
A Review Articles: Pantoea agglomerans in UTI- It is Bacteria Caused Urinary Tract Infection and Genomic Analysis related with Bacterial Resistance 尿路感染的pantoia凝聚是细菌引起的尿路感染以及与细菌耐药性相关的基因组分析
Pub Date : 2023-09-16 DOI: 10.55544/jrasb.2.4.20
Zainab Noori Hammed, Abdullah M. Taha, Tareq Abdulrazzaq Alabdali
Pantoea Spp. is a plant bacteria that has been identified as an emerging pathogen in humans related with outbreaks and many clinical infections. It is referred to as a "mystery bacterium of evil and good" since it may cause both bad and good. With the proposed investigation, the researchers hope to uncover a significant risk component that is connected with reoccurring urinary tract infections (UTI). They also hope to identify bacterial reasons and antibiotic susceptibility profiles that can be used to lower the threat of reinfection and prevent complications associated with recurrent UTI. In the existence of risk variables, the likelihood of developing a UTI increases; also, a correct susceptibility pattern increases the likelihood of achieving therapeutic effectiveness and preventing illness complications. Because of its capacity to infect immunocompromised persons and produce severe illness as a consequence of its multi - drug resistance, Pantoeasppregard is considered to be a dangerous opportunistic pathogen. In this paper we are going to focus on related bacteria, pathogenicity, resistance genes, classification.
Pantoea sp .是一种植物细菌,已被确定为与人类暴发和许多临床感染相关的新兴病原体。它被称为“恶与善的神秘细菌”,因为它可能导致坏和好。通过提出的调查,研究人员希望揭示与复发性尿路感染(UTI)相关的重要风险因素。他们还希望确定细菌原因和抗生素敏感性特征,可以用来降低再感染的威胁,预防与复发性尿路感染相关的并发症。存在风险变量时,发生尿路感染的可能性增加;此外,正确的易感性模式增加了实现治疗效果和预防疾病并发症的可能性。Pantoeasppregard是一种危险的机会性病原体,因为它具有感染免疫功能低下者的能力,并因其多重耐药性而导致严重疾病。本文就相关菌群、致病性、耐药基因、分类等方面作一综述。
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引用次数: 0
Impressive of Periodic and Insecticides on Leucinodes orbonalis Infestation on Solanum melongena 周期性和杀虫剂对茄类褐光粉虱侵染的影响
Pub Date : 2023-09-14 DOI: 10.55544/jrasb.2.4.19
Kamalesh Kumar
Six insecticides, namely Cypermethrin, Dimethoate, Carbaryl, Diflubenzuron, Neem and Bacillus thuringiensis (dipel) were tried against brinjal shoot, fruit borer and seed yield. Among them Cypermethrin, and Dimethoate were found to be the most effective in reducing the damage of shoot, fruits, and seed yield and thereby increasing the yield of brinjal fruits. In the present investigation, the shoot damage due to B.t. + diflubenzuron, B.t. + carbaryl was 8.52 and 6.84 percent in 2021- 22 and 9.93 and 9.45 in 2022-23 respectively, while the shoot infestation in control was 12.07 and 13.96 percent respectively, while B.t.alone proved to be very less against the shoot borer. Fruit infestation on both weight and number basis was minimum due to the treatment of B.T. application at transplanting followed by a combined application of B.T. + cypermethrin and B.T. + dimethoate. It might be due to that chemical pesticidal act as stressors and are frequently synergistic when combined with microorganisms such as Bacillus thuringienses.
研究了氯氰菊酯、乐果、威威利、双氟虫脲、印楝和苏云金芽孢杆菌6种杀虫剂对茄子幼苗、果螟和种子产量的影响。其中氯氰菊酯和乐果菊酯对降低油菜幼苗、果实和种子产量的损害,从而提高油菜果实产量的效果最好。在本调查中,2021- 22年溴氰菊酯、溴氰菊酯和西威因对雏菊的危害分别为8.52%和6.84%,2022-23年分别为9.93%和9.45%,而对照雏菊酯对雏菊的危害分别为12.07和13.96%,单用溴氰菊酯对雏菊的危害很小。由于在移栽时施用bt,然后施用bt +氯氰菊酯和bt +乐果乐,因此在重量和数量基础上,果实侵染都是最小的。这可能是由于化学杀菌剂作为应激源,当与苏云金芽孢杆菌等微生物结合使用时,经常产生协同作用。
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引用次数: 0
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International Journal For Research in Applied Sciences and Biotechnology
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