Pub Date : 2018-01-01DOI: 10.1504/IJLR.2018.10019602
E. Faweya, G. Adesakin, H. T. Akande, G. O. Olowomofe, T. Adewumi, G. Agunbiade
Radiation exposures at various dumpsites around three cities located in southwest Nigeria were assessed by gamma ray spectroscopy using a highly shielded Canberra NaI (Tl) detector. The average activity concentrations obtained for 40K were 535 ± 65, 430 ± 78, 471 ± 72 and 410 ± 29, 270 ± 84, 371 ± 27 Bq kg−1; the mean concentrations of 226Ra were 66 ± 4, 47 ± 3, 11 ± 1 and 57 ± 10, 49 ± 13, 59 ± 17 Bq kg−1; while the mean concentrations of 232Th were 55 ± 19, 29 ± 8, 13 ± 2 and 29 ± 3, 21 ± 5, 41 ± 12 Bq kg−1 for designated and undesignated sites in Abeokuta, Akure and Osogbo respectively. The highest mean absorbed dose rate obtained was 86 ± 17 nGy h−1. The total excess lifetime cancer risk ranged from 1.28 to 3.22 × 10−3 which is relatively higher than the world average.
{"title":"Assessment of excess lifetime cancer risk and radioactive heat production from waste dumpsites in three cities in Southwestern Nigeria","authors":"E. Faweya, G. Adesakin, H. T. Akande, G. O. Olowomofe, T. Adewumi, G. Agunbiade","doi":"10.1504/IJLR.2018.10019602","DOIUrl":"https://doi.org/10.1504/IJLR.2018.10019602","url":null,"abstract":"Radiation exposures at various dumpsites around three cities located in southwest Nigeria were assessed by gamma ray spectroscopy using a highly shielded Canberra NaI (Tl) detector. The average activity concentrations obtained for 40K were 535 ± 65, 430 ± 78, 471 ± 72 and 410 ± 29, 270 ± 84, 371 ± 27 Bq kg−1; the mean concentrations of 226Ra were 66 ± 4, 47 ± 3, 11 ± 1 and 57 ± 10, 49 ± 13, 59 ± 17 Bq kg−1; while the mean concentrations of 232Th were 55 ± 19, 29 ± 8, 13 ± 2 and 29 ± 3, 21 ± 5, 41 ± 12 Bq kg−1 for designated and undesignated sites in Abeokuta, Akure and Osogbo respectively. The highest mean absorbed dose rate obtained was 86 ± 17 nGy h−1. The total excess lifetime cancer risk ranged from 1.28 to 3.22 × 10−3 which is relatively higher than the world average.","PeriodicalId":14141,"journal":{"name":"International Journal of Low Radiation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66669492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.1504/ijlr.2018.098259
T. Ediagbonya, O. Gbolahan
In this study, different river samples from five different locations were analysed for the presence of radioactive isotopes along with some physicochemical parameters. The mean values of the radioa...
{"title":"Determination of radioactive isotopes and some physicochemical parameters in five different rivers in the south Ondo State, Nigeria","authors":"T. Ediagbonya, O. Gbolahan","doi":"10.1504/ijlr.2018.098259","DOIUrl":"https://doi.org/10.1504/ijlr.2018.098259","url":null,"abstract":"In this study, different river samples from five different locations were analysed for the presence of radioactive isotopes along with some physicochemical parameters. The mean values of the radioa...","PeriodicalId":14141,"journal":{"name":"International Journal of Low Radiation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1504/ijlr.2018.098259","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66669361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-31DOI: 10.1504/IJLR.2017.10008591
D. D. Jayanthi, C. Maniyan, S. Perumal
In this paper, annual effective radiation dose received by the residents of coastal villages of Kanya Kumari district of Tamil Nadu, India, is estimated. External exposure and the internal exposure are added to get the annual effective dose. External dose is calculated using TLD and the internal dose is calculated via inhalation and ingestion. Inhalation dose is calculated using SSNTD a passive measuring technique and the ingestion dose is calculated through the intake of water and the food (meals) by the public. For the present study ten coastal villages are selected and all the selected villages come under the natural high background radiation area. Among the study villages the annual effective dose varies from 3.7 mSv to 9.8 mSv.
{"title":"Estimation of annual effective dose due to external and internal exposure in the residents of coastal villages of Kanya Kumari district, Tamil Nadu, India","authors":"D. D. Jayanthi, C. Maniyan, S. Perumal","doi":"10.1504/IJLR.2017.10008591","DOIUrl":"https://doi.org/10.1504/IJLR.2017.10008591","url":null,"abstract":"In this paper, annual effective radiation dose received by the residents of coastal villages of Kanya Kumari district of Tamil Nadu, India, is estimated. External exposure and the internal exposure are added to get the annual effective dose. External dose is calculated using TLD and the internal dose is calculated via inhalation and ingestion. Inhalation dose is calculated using SSNTD a passive measuring technique and the ingestion dose is calculated through the intake of water and the food (meals) by the public. For the present study ten coastal villages are selected and all the selected villages come under the natural high background radiation area. Among the study villages the annual effective dose varies from 3.7 mSv to 9.8 mSv.","PeriodicalId":14141,"journal":{"name":"International Journal of Low Radiation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48387956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-31DOI: 10.1504/IJLR.2017.10008590
Tur Rahardjo, W. Mailana, T. Kisnanto, Darlina, S. Nurhayati, D. Tetriana, D. Ramadhani, M. Syaifudin
Mamuju in Indonesia has a highest average dose rate and considered as a high background radiation area (HBRA) in Indonesia. Here in this research a preliminary study to evaluate DNA damage using the alkaline comet assay in inhabitants of Takandeang village, Mamuju, was conducted. Blood samples from 55 healthy donors living in Takandeang village and 22 control samples were obtained and processed into the assay. Results showed that there were insignificant differences of comet tail length (TL) and tail moment (TM) between Takandeang village inhabitants and control samples (p = 0.578, 0.174). Regression analysis revealed that the DNA damage was increased with age in control samples, even though the correlation was not significant (p > 0.05). In contrast a significant negative correlation (p = 0.02) was observed in Takandeang inhabitants. Results found in this research should be validating in a larger study using more samples from Mamuju.
{"title":"Assessment of DNA damage in lymphocytes of Mamuju (a high background radiation area) inhabitants using alkaline single cell gel electrophoresis","authors":"Tur Rahardjo, W. Mailana, T. Kisnanto, Darlina, S. Nurhayati, D. Tetriana, D. Ramadhani, M. Syaifudin","doi":"10.1504/IJLR.2017.10008590","DOIUrl":"https://doi.org/10.1504/IJLR.2017.10008590","url":null,"abstract":"Mamuju in Indonesia has a highest average dose rate and considered as a high background radiation area (HBRA) in Indonesia. Here in this research a preliminary study to evaluate DNA damage using the alkaline comet assay in inhabitants of Takandeang village, Mamuju, was conducted. Blood samples from 55 healthy donors living in Takandeang village and 22 control samples were obtained and processed into the assay. Results showed that there were insignificant differences of comet tail length (TL) and tail moment (TM) between Takandeang village inhabitants and control samples (p = 0.578, 0.174). Regression analysis revealed that the DNA damage was increased with age in control samples, even though the correlation was not significant (p > 0.05). In contrast a significant negative correlation (p = 0.02) was observed in Takandeang inhabitants. Results found in this research should be validating in a larger study using more samples from Mamuju.","PeriodicalId":14141,"journal":{"name":"International Journal of Low Radiation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48684204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-31DOI: 10.1504/IJLR.2017.10008589
U. Elghawi, Feisal A. Abutweirat, Taha S. Barka
An investigation was carried out to find out the concentration of NORMs in evaporation ponds sludge in south eastern oilfield of Libya. Activity concentrations of 226Ra, 232Th and 40K in soil generated during oil production operations were determined using a gamma spectroscopy system based on high purity germanium (HPGe) detector. Concentrations ranged from 83 to 1000 Bq kg−1 for 226Ra, 59 to 315 Bq kg−1 for 232Th and 109 to 304 Bq kg−1 for 40K. To evaluate the radiological effects, radium equivalent activity and external hazard are calculated. The magnitude of these results demonstrates the need of these ponds for a special treatment on site to reduce the exposure to a value below 100 μSv/y, by mixing the pond after drying the lagoon with clean soil to reduce the dose rate and minimise the environmental impact of NORM.
{"title":"Evaluation of naturally occurring radioactive materials in oilfields of south east of Libya","authors":"U. Elghawi, Feisal A. Abutweirat, Taha S. Barka","doi":"10.1504/IJLR.2017.10008589","DOIUrl":"https://doi.org/10.1504/IJLR.2017.10008589","url":null,"abstract":"An investigation was carried out to find out the concentration of NORMs in evaporation ponds sludge in south eastern oilfield of Libya. Activity concentrations of 226Ra, 232Th and 40K in soil generated during oil production operations were determined using a gamma spectroscopy system based on high purity germanium (HPGe) detector. Concentrations ranged from 83 to 1000 Bq kg−1 for 226Ra, 59 to 315 Bq kg−1 for 232Th and 109 to 304 Bq kg−1 for 40K. To evaluate the radiological effects, radium equivalent activity and external hazard are calculated. The magnitude of these results demonstrates the need of these ponds for a special treatment on site to reduce the exposure to a value below 100 μSv/y, by mixing the pond after drying the lagoon with clean soil to reduce the dose rate and minimise the environmental impact of NORM.","PeriodicalId":14141,"journal":{"name":"International Journal of Low Radiation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45190696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-31DOI: 10.1504/IJLR.2017.10008580
Nitin Gupta, K. Kant, Maneesha Garg
Environmental radioactivity due to radon, thoron and their progenies in the ambient air in the multi-storeyed malls situated in Delhi National Capital Region (NCR) including district Faridabad, Haryana (India) was evaluated using LR-115 (type-II) SSNTDs. The average value of activity in different seasons due to radon and thoron varied from 18.45 ± 1.95 Bqm−3 to 45.37 ± 4.69 Bqm−3 and 10.64 ± 0.94 Bqm−3 to 22.91 ± 1.88 Bqm−3 respectively. The collective annual exposure and annual effective dose due to radon and thoron varied from 45.37 × 10−3 WLM to 295.67 × 10−3 WLM with an average value of (159.88 ± 3.66) × 10−3 WLM, and 0.17 mSv to 1.13 mSv with an average value of 0.61 ± 0.01 mSv respectively during the four seasons of the year. Owing to poor ventilation in basement of malls, the annual effective dose is high compared with upper floors of the malls where proper ventilation is provided.
{"title":"Radon-thoron and their progeny dosimetry in multi-storeyed malls in Delhi NCR (India) using plastic track detectors","authors":"Nitin Gupta, K. Kant, Maneesha Garg","doi":"10.1504/IJLR.2017.10008580","DOIUrl":"https://doi.org/10.1504/IJLR.2017.10008580","url":null,"abstract":"Environmental radioactivity due to radon, thoron and their progenies in the ambient air in the multi-storeyed malls situated in Delhi National Capital Region (NCR) including district Faridabad, Haryana (India) was evaluated using LR-115 (type-II) SSNTDs. The average value of activity in different seasons due to radon and thoron varied from 18.45 ± 1.95 Bqm−3 to 45.37 ± 4.69 Bqm−3 and 10.64 ± 0.94 Bqm−3 to 22.91 ± 1.88 Bqm−3 respectively. The collective annual exposure and annual effective dose due to radon and thoron varied from 45.37 × 10−3 WLM to 295.67 × 10−3 WLM with an average value of (159.88 ± 3.66) × 10−3 WLM, and 0.17 mSv to 1.13 mSv with an average value of 0.61 ± 0.01 mSv respectively during the four seasons of the year. Owing to poor ventilation in basement of malls, the annual effective dose is high compared with upper floors of the malls where proper ventilation is provided.","PeriodicalId":14141,"journal":{"name":"International Journal of Low Radiation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43435149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-31DOI: 10.1504/IJLR.2017.10008588
S. Alausa, O. O. Omotosho
Radioactivity data in food and farm soil in sedimentary rocky areas like Ayetoro, Nigeria, are scarce. Maize, cassava and the underneath soil samples were collected from Ayetoro. The 40K, 226Ra and 232Th activity concentrations in the samples were measured with a gamma ray spectrometer. The soil-to-food crop transfer factors, ingestion effective dose rates due to the crops and the outdoor effective dose rates due to soils were evaluated. The mean 40K, 226Ra and 232Th activity concentrations in maize were 160.3 ± 66.5 Bqkg−1, 18.1 ± 7.1 Bqkg−1 and 15.0 ± 8.0 Bqkg−1 respectively and the soils were 671.5 ± 352.9 Bqkg−1, 66.8 ± 25.3 Bqkg−1 and 62.1 ± 27.9 Bqkg−1 for 40K, 226Ra and 232Th respectively. The mean activity concentrations in cassava were 294.6 ± 137.2 Bqkg−1, 28.6 ± 14.9 Bqkg−1 and 18.2 ± 13.0 Bqkg−1 for 40K, 226Ra and 232Th respectively and the soils were 679.5 ± 281.1 Bqkg−1, 66.8 ± 32.7 Bqkg−1 and 49.7 ± 46.9 Bqkg−1 for 40K, 226Ra and 232Th respectively. The results indicated that the activity concentrations, ingestion effective dose and outdoor effective dose are low and no serious radiological health impact is expected.
{"title":"Natural radioactivity in farm soils and major food crops grown in Ayetoro, Ogun State, Southwestern Nigeria","authors":"S. Alausa, O. O. Omotosho","doi":"10.1504/IJLR.2017.10008588","DOIUrl":"https://doi.org/10.1504/IJLR.2017.10008588","url":null,"abstract":"Radioactivity data in food and farm soil in sedimentary rocky areas like Ayetoro, Nigeria, are scarce. Maize, cassava and the underneath soil samples were collected from Ayetoro. The 40K, 226Ra and 232Th activity concentrations in the samples were measured with a gamma ray spectrometer. The soil-to-food crop transfer factors, ingestion effective dose rates due to the crops and the outdoor effective dose rates due to soils were evaluated. The mean 40K, 226Ra and 232Th activity concentrations in maize were 160.3 ± 66.5 Bqkg−1, 18.1 ± 7.1 Bqkg−1 and 15.0 ± 8.0 Bqkg−1 respectively and the soils were 671.5 ± 352.9 Bqkg−1, 66.8 ± 25.3 Bqkg−1 and 62.1 ± 27.9 Bqkg−1 for 40K, 226Ra and 232Th respectively. The mean activity concentrations in cassava were 294.6 ± 137.2 Bqkg−1, 28.6 ± 14.9 Bqkg−1 and 18.2 ± 13.0 Bqkg−1 for 40K, 226Ra and 232Th respectively and the soils were 679.5 ± 281.1 Bqkg−1, 66.8 ± 32.7 Bqkg−1 and 49.7 ± 46.9 Bqkg−1 for 40K, 226Ra and 232Th respectively. The results indicated that the activity concentrations, ingestion effective dose and outdoor effective dose are low and no serious radiological health impact is expected.","PeriodicalId":14141,"journal":{"name":"International Journal of Low Radiation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47891934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-31DOI: 10.1504/IJLR.2017.10008581
S. Fares
Determination of the natural radionuclide contents of soil and rock samples collected from some mountains and valleys in Sinai, Egypt, has been carried out using gamma spectrometric techniques. The total average concentrations of radionuclides 226Ra, 238U, 232Th, and 40K were (51.37, 50.02, 19.34, and 286.66 Bq/kg), respectively. The total average absorbed dose rate in the study areas is found to be 47.08 nGy/h, whereas the indoor and outdoor annual effective dose equivalent has an average value of 0.23 and 0.06 mSv/y respectively. The range of 226Ra activity was found from 11.15 ± 0.96 Bq/kg to 135.85 ± 11.68 Bq/kg. The results of the present study are discussed and compared with internationally recommended values. The concentrations of radon gas in the air were determined as well as the activity concentrations of 222Rn in vegetables. In the present study some mathematical equations models are used to estimate the activity concentrations of 222Rn in the air.
{"title":"Evaluation of environmental radioactivity impacts and its associated radiological hazards with monitoring of radon-222 in rock and sand samples collected from some mountains and valleys in Sinai Area, Egypt","authors":"S. Fares","doi":"10.1504/IJLR.2017.10008581","DOIUrl":"https://doi.org/10.1504/IJLR.2017.10008581","url":null,"abstract":"Determination of the natural radionuclide contents of soil and rock samples collected from some mountains and valleys in Sinai, Egypt, has been carried out using gamma spectrometric techniques. The total average concentrations of radionuclides 226Ra, 238U, 232Th, and 40K were (51.37, 50.02, 19.34, and 286.66 Bq/kg), respectively. The total average absorbed dose rate in the study areas is found to be 47.08 nGy/h, whereas the indoor and outdoor annual effective dose equivalent has an average value of 0.23 and 0.06 mSv/y respectively. The range of 226Ra activity was found from 11.15 ± 0.96 Bq/kg to 135.85 ± 11.68 Bq/kg. The results of the present study are discussed and compared with internationally recommended values. The concentrations of radon gas in the air were determined as well as the activity concentrations of 222Rn in vegetables. In the present study some mathematical equations models are used to estimate the activity concentrations of 222Rn in the air.","PeriodicalId":14141,"journal":{"name":"International Journal of Low Radiation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49413306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-29DOI: 10.1504/ijlr.2015.074409
C. Silva, C. C. Júnior
The metropolitan area of Recife is characterised by high population density. Owing to the lack of radiometric assessments in public water supply, this work was designed to determine 222Rn concentration in public water supply samples of the metropolitan area from Recife with high natural radiation in the state of Pernambuco, Brazil. To determine 222Rn concentrations the technique of liquid scintillation was employed. The samples showed concentrations ranging from 5 Bq l−1 to 84 Bq l−1. In this report, the results and the radiation-induced health effects are presented as well as discussed.
{"title":"222Rn in public water supply and risk estimate of cancer in the metropolitan area from Recife, Brazil","authors":"C. Silva, C. C. Júnior","doi":"10.1504/ijlr.2015.074409","DOIUrl":"https://doi.org/10.1504/ijlr.2015.074409","url":null,"abstract":"The metropolitan area of Recife is characterised by high population density. Owing to the lack of radiometric assessments in public water supply, this work was designed to determine 222Rn concentration in public water supply samples of the metropolitan area from Recife with high natural radiation in the state of Pernambuco, Brazil. To determine 222Rn concentrations the technique of liquid scintillation was employed. The samples showed concentrations ranging from 5 Bq l−1 to 84 Bq l−1. In this report, the results and the radiation-induced health effects are presented as well as discussed.","PeriodicalId":14141,"journal":{"name":"International Journal of Low Radiation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1504/ijlr.2015.074409","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66669393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-01-29DOI: 10.1504/IJLR.2015.074405
Reza Vazifehmand, S. Saber, Abbas Takavr, Dhuha Ali, Tina Saber, Farnaz Takavar
Radioactivity is known to induce tumours, chromosome lesions, and mini-satellite length mutations, but also effects on the DNA sequence. Ramsar region, in the north of Iran with the highest background of natural radiation (226Ra) in the world, with a densely populated area, offers an opportunity to characterise radiation-associated DNA mutations. We sampled 30 individuals from this area and 15 cases from Tehran as controls. We sequenced their mtDNA and found multiple variations in multiple nucleotide positions in Ramsar inhabitants. 16519 and T > C were the most frequent NPS and variables in our study. In this preliminary investigation, we conclude that an elevated level of natural background radiation in Ramsar region had a significant effect on the control region of mtDNA. We think this is the first report from Ramsar in this field. Moreover, using molecular and biological pathways and study of gene expression to understand the cellular and molecular response of human mtDNA to low-dose radiation exposure is recommended.
{"title":"Effect of high background natural radioactivity on human mitochondrial DNA in Ramsar, the north of Iran","authors":"Reza Vazifehmand, S. Saber, Abbas Takavr, Dhuha Ali, Tina Saber, Farnaz Takavar","doi":"10.1504/IJLR.2015.074405","DOIUrl":"https://doi.org/10.1504/IJLR.2015.074405","url":null,"abstract":"Radioactivity is known to induce tumours, chromosome lesions, and mini-satellite length mutations, but also effects on the DNA sequence. Ramsar region, in the north of Iran with the highest background of natural radiation (226Ra) in the world, with a densely populated area, offers an opportunity to characterise radiation-associated DNA mutations. We sampled 30 individuals from this area and 15 cases from Tehran as controls. We sequenced their mtDNA and found multiple variations in multiple nucleotide positions in Ramsar inhabitants. 16519 and T > C were the most frequent NPS and variables in our study. In this preliminary investigation, we conclude that an elevated level of natural background radiation in Ramsar region had a significant effect on the control region of mtDNA. We think this is the first report from Ramsar in this field. Moreover, using molecular and biological pathways and study of gene expression to understand the cellular and molecular response of human mtDNA to low-dose radiation exposure is recommended.","PeriodicalId":14141,"journal":{"name":"International Journal of Low Radiation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1504/IJLR.2015.074405","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66669341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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