Pub Date : 2024-01-01DOI: 10.1177/22808000241257124
Colleen Nancy Ward, Payton E LeBlanc, Robert Edward Burrell
Adhesions are fibrous tissue connections which are a common complication of surgical procedures and may be prevented by protecting tissue surfaces and reducing inflammation. The combination of biodegradable polymers and nanocrystalline silver can be used to create an anti-inflammatory gel to be applied during surgery. In this study, sodium hyaluronate and sodium carboxymethyl cellulose were added in concentrations from 0.25% to 1% w/v to aqueous nanocrystalline silver solutions to create viscous gels. Gels were loaded into dialysis cassettes and placed in PBS for 3 days. pH was adjusted using potassium phosphate monobasic and sodium hydroxide. Release of silver into the PBS was measured at several time points. Polymer degradation was compared by measuring the viscosity of the gels before and after the experiment. Gels lost up to 84% of initial viscosity over 3 days and released between 24% and 41% of the added silver. Gels with higher initial viscosity did not have a greater degree of degradation, as measured by percent viscosity reduction, but still resulted in a higher final viscosity. Silver release was not significantly impacted by pH or composition, but still varied between experimental groups.
{"title":"Effects of composition and pH on the degradation of hyaluronate and carboxymethyl cellulose gels and release of nanocrystalline silver.","authors":"Colleen Nancy Ward, Payton E LeBlanc, Robert Edward Burrell","doi":"10.1177/22808000241257124","DOIUrl":"https://doi.org/10.1177/22808000241257124","url":null,"abstract":"<p><p>Adhesions are fibrous tissue connections which are a common complication of surgical procedures and may be prevented by protecting tissue surfaces and reducing inflammation. The combination of biodegradable polymers and nanocrystalline silver can be used to create an anti-inflammatory gel to be applied during surgery. In this study, sodium hyaluronate and sodium carboxymethyl cellulose were added in concentrations from 0.25% to 1% w/v to aqueous nanocrystalline silver solutions to create viscous gels. Gels were loaded into dialysis cassettes and placed in PBS for 3 days. pH was adjusted using potassium phosphate monobasic and sodium hydroxide. Release of silver into the PBS was measured at several time points. Polymer degradation was compared by measuring the viscosity of the gels before and after the experiment. Gels lost up to 84% of initial viscosity over 3 days and released between 24% and 41% of the added silver. Gels with higher initial viscosity did not have a greater degree of degradation, as measured by percent viscosity reduction, but still resulted in a higher final viscosity. Silver release was not significantly impacted by pH or composition, but still varied between experimental groups.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1177/22808000241273951
{"title":"Retraction Comparison of adhesive bond strength among fiber reinforced post and core with different cementation techniques: In vitro study.","authors":"","doi":"10.1177/22808000241273951","DOIUrl":"https://doi.org/10.1177/22808000241273951","url":null,"abstract":"","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1177/22808000241236020
Najoua Salhi, Otman El Guourrami, Abdelaali Balahbib, Lamiae Rouas, Siham Moussaid, Amina Moutawalli, Fatima Zahra Benkhouili, Mouna Ameggouz, Riaz Ullah, Amal Alotaibi, Abdelhakim Bouyahya, Ching Siang Tan, Long Chiau Ming, My El Abbes Faouzi, Yahya Cherrah
Objective: To investigate the Pinus halepensis extracts and determine its healing and antibacterial effects, and to evaluate the treatment of skin burns.
Methods: Aqueous and ethanolic extracts and topical based on Aleppo pine plant extracts were prepared. Thirty male and female Wistar rats were used to study the cutaneous toxicity of extracts from the bark of P. halepensis. The extracts' healing potential for burn wounds were also assessed by evaluating the clinical and macroscopic aspects of the wounds. The antibacterial activity of crude extracts of P. halepensis as well as its wound healing abilities was verified in this investigation.
Results: In animals with acute dermal toxicity, there were no signs of treatment-related toxicity or death. The extracts of these plants could be transformed into phytomedicines for the treatment of infected wounds. The results demonstrated that formulated ointments are successful in treating second-degree burns in rats and may be suitable for the short-term therapeutic treatment of second-degree burns.
Conclusion: This study successfully answered our problem, regarding the efficacy of our extract for treating second-degree burns in rats. Further studies are needed to confirm these results by identifying the molecules responsible for these activities and examining their mechanism of action.
{"title":"Application of Aleppo pine extract for skin burn treatment.","authors":"Najoua Salhi, Otman El Guourrami, Abdelaali Balahbib, Lamiae Rouas, Siham Moussaid, Amina Moutawalli, Fatima Zahra Benkhouili, Mouna Ameggouz, Riaz Ullah, Amal Alotaibi, Abdelhakim Bouyahya, Ching Siang Tan, Long Chiau Ming, My El Abbes Faouzi, Yahya Cherrah","doi":"10.1177/22808000241236020","DOIUrl":"10.1177/22808000241236020","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the <i>Pinus halepensis</i> extracts and determine its healing and antibacterial effects, and to evaluate the treatment of skin burns.</p><p><strong>Methods: </strong>Aqueous and ethanolic extracts and topical based on Aleppo pine plant extracts were prepared. Thirty male and female Wistar rats were used to study the cutaneous toxicity of extracts from the bark of <i>P. halepensis</i>. The extracts' healing potential for burn wounds were also assessed by evaluating the clinical and macroscopic aspects of the wounds. The antibacterial activity of crude extracts of <i>P. halepensis</i> as well as its wound healing abilities was verified in this investigation.</p><p><strong>Results: </strong>In animals with acute dermal toxicity, there were no signs of treatment-related toxicity or death. The extracts of these plants could be transformed into phytomedicines for the treatment of infected wounds. The results demonstrated that formulated ointments are successful in treating second-degree burns in rats and may be suitable for the short-term therapeutic treatment of second-degree burns.</p><p><strong>Conclusion: </strong>This study successfully answered our problem, regarding the efficacy of our extract for treating second-degree burns in rats. Further studies are needed to confirm these results by identifying the molecules responsible for these activities and examining their mechanism of action.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140094026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1177/22808000241248887
Sasireka Rajendran, Madheswaran Muthusamy
Objective: Chitin a natural polymer is abundant in several sources such as shells of crustaceans, mollusks, insects, and fungi. Several possible attempts have been made to recover chitin because of its importance in biomedical applications in various forms such as hydrogel, nanoparticles, nanosheets, nanowires, etc. Among them, deep eutectic solvents have gained much consideration because of their eco-friendly and recyclable nature. However, several factors need to be addressed to obtain a pure form of chitin with a high yield. The development of an innovative system for the production of quality chitin is of prime importance and is still challenging.
Methods: The present study intended to develop a novel and robust approach to investigate chitin purity from various crustacean shell wastes using deep eutectic solvents. This investigation will assist in envisaging the important influencing parameters to obtain a pure form of chitin via a machine learning approach. Different machine learning algorithms have been proposed to model chitin purity by considering the enormous experimental dataset retrieved from previously conducted experiments. Several input variables have been selected to assess chitin purity as the output variable.
Results: The statistical criteria of the proposed model have been critically investigated and it was observed that the results indicate XGBoost has the maximum predictive accuracy of 0.95 compared with other selected models. The RMSE and MAE values were also minimal in the XGBoost model. In addition, it revealed better input variables to obtain pure chitin with minimal processing time.
Conclusion: This study validates that machine learning paves the way for complex problems with substantial datasets and can be an inexpensive and time-saving model for analyzing chitin purity from crustacean shells.
目的甲壳素是一种天然聚合物,在甲壳类动物、软体动物、昆虫和真菌的外壳等多种来源中含量丰富。由于甲壳素在生物医学应用中的重要性,人们已尝试以各种形式(如水凝胶、纳米颗粒、纳米片、纳米线等)回收甲壳素。其中,深共晶溶剂因其环保和可回收的特性而备受关注。然而,要获得高产率的纯甲壳素需要解决几个因素。开发一种生产优质甲壳素的创新系统至关重要,但目前仍面临挑战:本研究旨在开发一种新颖、稳健的方法,利用深共晶溶剂从各种甲壳类贝壳废料中研究甲壳素的纯度。这项研究将有助于通过机器学习方法设想获得纯甲壳素的重要影响参数。考虑到从以前进行的实验中获取的大量实验数据集,我们提出了不同的机器学习算法,以建立甲壳素纯度模型。我们选择了几个输入变量来评估作为输出变量的甲壳素纯度:对所提模型的统计标准进行了严格研究,结果表明,与其他选定模型相比,XGBoost 的预测准确率最高,达到 0.95。XGBoost 模型的 RMSE 和 MAE 值也最小。此外,它还揭示了更好的输入变量,从而以最短的加工时间获得纯甲壳素:这项研究证明,机器学习为解决复杂问题和大量数据集铺平了道路,并且可以成为分析甲壳类动物甲壳素纯度的一种廉价省时的模型。
{"title":"Exploring the purity of chitin from crustacean sources using deep eutectic solvents: A machine learning approach.","authors":"Sasireka Rajendran, Madheswaran Muthusamy","doi":"10.1177/22808000241248887","DOIUrl":"https://doi.org/10.1177/22808000241248887","url":null,"abstract":"<p><strong>Objective: </strong>Chitin a natural polymer is abundant in several sources such as shells of crustaceans, mollusks, insects, and fungi. Several possible attempts have been made to recover chitin because of its importance in biomedical applications in various forms such as hydrogel, nanoparticles, nanosheets, nanowires, etc. Among them, deep eutectic solvents have gained much consideration because of their eco-friendly and recyclable nature. However, several factors need to be addressed to obtain a pure form of chitin with a high yield. The development of an innovative system for the production of quality chitin is of prime importance and is still challenging.</p><p><strong>Methods: </strong>The present study intended to develop a novel and robust approach to investigate chitin purity from various crustacean shell wastes using deep eutectic solvents. This investigation will assist in envisaging the important influencing parameters to obtain a pure form of chitin via a machine learning approach. Different machine learning algorithms have been proposed to model chitin purity by considering the enormous experimental dataset retrieved from previously conducted experiments. Several input variables have been selected to assess chitin purity as the output variable.</p><p><strong>Results: </strong>The statistical criteria of the proposed model have been critically investigated and it was observed that the results indicate XGBoost has the maximum predictive accuracy of 0.95 compared with other selected models. The RMSE and MAE values were also minimal in the XGBoost model. In addition, it revealed better input variables to obtain pure chitin with minimal processing time.</p><p><strong>Conclusion: </strong>This study validates that machine learning paves the way for complex problems with substantial datasets and can be an inexpensive and time-saving model for analyzing chitin purity from crustacean shells.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140921974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1177/22808000231221067
Emre Fatih Ediz, Cansu Güneş, Meltem Demirel Kars, Ahmet Avcı
The research on tissue engineering applications has been progressing to manufacture ideal tissue scaffold biomaterials. In this study, a double-layered electrospun biofiber scaffold biomaterial including Polycaprolactone (PCL)/Collagen (COL) fibrous inner layer and PCL/ Momordica charantia (MC) and Hypericum perforatum (HP) oils fibrous outer layer was developed to manufacture a functional, novel tissue scaffold with the advantageous mechanical and biological properties. The main approach was to combine the natural perspective using medicinal oils with an engineering point of view to fabricate a potential functional scaffold for tissue engineering. Medicinal plants MC and HP are rich in functional oils and incorporation of them in a tissue scaffold will unveil their potential to augment both new tissue formation and wound healing. In this study, a novel double-layered scaffold prototype was fabricated using electrospinning technique with two PCL fiber layers, first is composed of collagen, and second is composed of oils extracted from medicinal plants. Initially, the composition of plant oils was analyzed. Thereafter the biofiber scaffold layers were fabricated and were evaluated in terms of morphology, physicochemistry, thermal and mechanical features, wettability, in vitro bio-degradability. Double-layered scaffold prototype was further analyzed in terms of in vitro biocompatibility and antibacterial effect. The medicinal oils blend provided antioxidant and antibacterial properties to the novel PCL/Oils layer. The results signify that inner PCL/COL layer exhibited advanced biodegradability of 8.5% compared to PCL and enhanced wettability with 11.7° contact angle. Strength of scaffold prototype was 5.98 N/mm2 thanks to the elastic PCL fibrous matrix. The double-layered functional biofiber scaffold enabled 92% viability after 72 h contact with fibroblast cells and furthermore provided feasible attachment sites for the cells. The functional scaffold prototype's noteworthy mechanical, chemical, and biological features enable it to be suggested as a different novel biomaterial with the potential to be utilized in tissue engineering applications.
{"title":"In vitro assessment of <i>Momordica charantia</i>/<i>Hypericum perforatum</i> oils loaded PCL/Collagen fibers: Novel scaffold for tissue engineering.","authors":"Emre Fatih Ediz, Cansu Güneş, Meltem Demirel Kars, Ahmet Avcı","doi":"10.1177/22808000231221067","DOIUrl":"https://doi.org/10.1177/22808000231221067","url":null,"abstract":"<p><p>The research on tissue engineering applications has been progressing to manufacture ideal tissue scaffold biomaterials. In this study, a double-layered electrospun biofiber scaffold biomaterial including Polycaprolactone (PCL)/Collagen (COL) fibrous inner layer and PCL/ <i>Momordica charantia</i> (MC) and <i>Hypericum perforatum (HP)</i> oils fibrous outer layer was developed to manufacture a functional, novel tissue scaffold with the advantageous mechanical and biological properties. The main approach was to combine the natural perspective using medicinal oils with an engineering point of view to fabricate a potential functional scaffold for tissue engineering. Medicinal plants MC and HP are rich in functional oils and incorporation of them in a tissue scaffold will unveil their potential to augment both new tissue formation and wound healing. In this study, a novel double-layered scaffold prototype was fabricated using electrospinning technique with two PCL fiber layers, first is composed of collagen, and second is composed of oils extracted from medicinal plants. Initially, the composition of plant oils was analyzed. Thereafter the biofiber scaffold layers were fabricated and were evaluated in terms of morphology, physicochemistry, thermal and mechanical features, wettability, in vitro bio-degradability. Double-layered scaffold prototype was further analyzed in terms of in vitro biocompatibility and antibacterial effect. The medicinal oils blend provided antioxidant and antibacterial properties to the novel PCL/Oils layer. The results signify that inner PCL/COL layer exhibited advanced biodegradability of 8.5% compared to PCL and enhanced wettability with 11.7° contact angle. Strength of scaffold prototype was 5.98 N/mm<sup>2</sup> thanks to the elastic PCL fibrous matrix. The double-layered functional biofiber scaffold enabled 92% viability after 72 h contact with fibroblast cells and furthermore provided feasible attachment sites for the cells. The functional scaffold prototype's noteworthy mechanical, chemical, and biological features enable it to be suggested as a different novel biomaterial with the potential to be utilized in tissue engineering applications.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139466654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1177/22808000231222708
{"title":"Retraction Notice: \"Role of mineral trioxide aggregate in dentistry: A bibliometric analysis using Scopus database\".","authors":"","doi":"10.1177/22808000231222708","DOIUrl":"https://doi.org/10.1177/22808000231222708","url":null,"abstract":"","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139650821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study demonstrates the feasibility of using Irvingia gabonensis shell particulates (IGSp) as alternative reinforcing materials in the development of aluminium-based composites. In this experimental study, the microstructure, phase composition, and mechanical behaviour of Al-10Zn-1.63Si/xIGSp (wt%, x = 1, 3, 5 and 7) composites were investigated. The Al-10Zn-1.63Si based composites were fabricated using the stir-casting technique. Different weight percentages (1, 3, 5 and 7) of IGSp were added to the Al-10Zn-1.63Si matrix. The chemical constituents of the IGSp were determined using X-ray fluorescence (XRF). The grain characteristics and phase(s) compositions were determined using Scanning Electron Microscopy (SEM) and X-ray diffractometer (XRD). The ultimate tensile strength, hardness, and impact strength of the developed composites were also determined. The SEM and XRD results revealed the presence of different phases: aluminium phosphate (Al16P16O64), gahnite (ZnAl2O4), andalusite (Al2SiO5), Quartz (SiO2) and aluminium silicate (Al2O3.5.SiO2). Results show that addition of IGSp led to an increase in ultimate tensile strength, with the highest value (128 MPa) obtained at 3 wt% IGSp. The hardness of the composites increased with increasing concentrations of IGSp, reaching a maximum value of 285 HV after adding 7 wt% IGSp. The impact strength improved with the addition of IGSp, with the highest value (30 J) obtained at 1 wt% IGSp. The improvements in mechanical properties were attributed to the dispersion of three major phases: aluminium silicate (Al2O3.54.SiO2), Al16P16O64 and Al2O3.54.SiO2. These phases contributed to the enhanced strength and hardness of the composites. The study noted a sudden decrease in ultimate tensile strength with higher concentrations of IGSp due to the increase in the intensities of Al16P16O64 and precipitation of hard but brittle new phase; Al2Si60.6O126.33. The study concludes that IGSp has the potential to serve as an alternative reinforcing material for aluminium-based composites.
{"title":"Evaluation of microstructure evolution and mechanical properties of Al-10Zn-1.63Si/<i>Irvingia gabonensis</i> particulates alloy composites.","authors":"Chukwuneke Jeremiah Lekwuwa, Sinebe Jude Ebieladoh, Umahi Justice Chidi, Nnakwo Kingsley Chidi, Olisakwe Henry Chukwuemeka","doi":"10.1177/22808000241236021","DOIUrl":"10.1177/22808000241236021","url":null,"abstract":"<p><p>This study demonstrates the feasibility of using <i>Irvingia gabonensis</i> shell particulates (IGSp) as alternative reinforcing materials in the development of aluminium-based composites. In this experimental study, the microstructure, phase composition, and mechanical behaviour of Al-10Zn-1.63Si/xIGSp (wt%, x = 1, 3, 5 and 7) composites were investigated. The Al-10Zn-1.63Si based composites were fabricated using the stir-casting technique. Different weight percentages (1, 3, 5 and 7) of IGSp were added to the Al-10Zn-1.63Si matrix. The chemical constituents of the IGSp were determined using X-ray fluorescence (XRF). The grain characteristics and phase(s) compositions were determined using Scanning Electron Microscopy (SEM) and X-ray diffractometer (XRD). The ultimate tensile strength, hardness, and impact strength of the developed composites were also determined. The SEM and XRD results revealed the presence of different phases: aluminium phosphate (Al<sub>16</sub>P<sub>16</sub>O<sub>64</sub>), gahnite (ZnAl<sub>2</sub>O<sub>4</sub>), andalusite (Al<sub>2</sub>SiO<sub>5</sub>), Quartz (SiO<sub>2</sub>) and aluminium silicate (Al<sub>2</sub>O<sub>3.5</sub>.SiO<sub>2</sub>). Results show that addition of IGSp led to an increase in ultimate tensile strength, with the highest value (128 MPa) obtained at 3 wt% IGSp. The hardness of the composites increased with increasing concentrations of IGSp, reaching a maximum value of 285 HV after adding 7 wt% IGSp. The impact strength improved with the addition of IGSp, with the highest value (30 J) obtained at 1 wt% IGSp. The improvements in mechanical properties were attributed to the dispersion of three major phases: aluminium silicate (Al<sub>2</sub>O<sub>3.54.</sub>SiO<sub>2</sub>), Al<sub>16</sub>P<sub>16</sub>O<sub>64</sub> and Al<sub>2</sub>O<sub>3.54.</sub>SiO<sub>2</sub>. These phases contributed to the enhanced strength and hardness of the composites. The study noted a sudden decrease in ultimate tensile strength with higher concentrations of IGSp due to the increase in the intensities of Al<sub>16</sub>P<sub>16</sub>O<sub>64</sub> and precipitation of hard but brittle new phase; Al<sub>2</sub>Si<sub>60.</sub>6O126.33. The study concludes that IGSp has the potential to serve as an alternative reinforcing material for aluminium-based composites.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140131496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1177/22808000241235994
Arif Bolaca, Yıldırım Erdoğan
Objective: To evaluate the effect of different CAD/CAM materials and occlusal thicknesses on the fracture resistance of primary molar crowns.
Methods: Sixty extracted primary molar teeth were prepared and randomly divided into six experimental groups according to the material and thickness. Primary molar crowns with a central groove thickness of 0.3 and 0.5 mm were fabricated from CAD/CAM zirconia (group Z), zirconia-reinforced lithium silicate (group ZLS), and pre-polymerized composite resin blocks (group C). Each crown was cemented with self-adhesive resin cement on the prepared tooth. All specimens were subjected to fracture tests until fracture. Fracture load values were recorded in Newtons (N). Data were statistically analyzed using a two-way analysis of variance (ANOVA) followed by Tukey multiple comparison test.
Results: The highest fracture load values were obtained in group Z at 0.5 mm occlusal thickness and were significantly higher compared with the other experimental groups (p < 0.05). Although the lowest fracture load values were obtained in group ZLS at 0.3 mm occlusal thickness, all the tested CAD/CAM primary molar crowns at both thicknesses demonstrated fracture load values exceeding reported chewing force in pediatric patients.
Conclusion: CAD/CAM primary molar crowns with reduced occlusal thickness may be used for the full-coverage restoration of primary molar teeth.
{"title":"Fracture resistance evaluation of CAD/CAM zirconia and composite primary molar crowns with different occlusal thicknesses.","authors":"Arif Bolaca, Yıldırım Erdoğan","doi":"10.1177/22808000241235994","DOIUrl":"10.1177/22808000241235994","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effect of different CAD/CAM materials and occlusal thicknesses on the fracture resistance of primary molar crowns.</p><p><strong>Methods: </strong>Sixty extracted primary molar teeth were prepared and randomly divided into six experimental groups according to the material and thickness. Primary molar crowns with a central groove thickness of 0.3 and 0.5 mm were fabricated from CAD/CAM zirconia (group Z), zirconia-reinforced lithium silicate (group ZLS), and pre-polymerized composite resin blocks (group C). Each crown was cemented with self-adhesive resin cement on the prepared tooth. All specimens were subjected to fracture tests until fracture. Fracture load values were recorded in Newtons (N). Data were statistically analyzed using a two-way analysis of variance (ANOVA) followed by Tukey multiple comparison test.</p><p><strong>Results: </strong>The highest fracture load values were obtained in group Z at 0.5 mm occlusal thickness and were significantly higher compared with the other experimental groups (<i>p</i> < 0.05). Although the lowest fracture load values were obtained in group ZLS at 0.3 mm occlusal thickness, all the tested CAD/CAM primary molar crowns at both thicknesses demonstrated fracture load values exceeding reported chewing force in pediatric patients.</p><p><strong>Conclusion: </strong>CAD/CAM primary molar crowns with reduced occlusal thickness may be used for the full-coverage restoration of primary molar teeth.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139990162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.1177/22808000241250118
Sareh Habibzadeh, Faranak Khamisi, Seyed Ali Mosaddad, Gustavo Vicentis de Oliveira Fernandes, Artak Heboyan
Despite the development of implant-supported prostheses, there are still patients for whom conservative treatments such as resin-bonded fixed dental prostheses (RBFDPs) are more appropriate. This study's objective was to analyze the available research on full-ceramic RBFDPs. In this study, Web of Science, MEDLINE/PubMed, Scopus, Embase, Cochrane Library, and Google Scholar databases were searched for articles published in English between 2010 and 2020. A total of 14 studies were reviewed based on the eligibility criteria. The results showed that using a cantilever design with one abutment had an advantage over two abutments. Additionally, it was proposed that preparations designed with retentive aids, such as a proximal box, groove, and pinhole, could improve RBFDP survival rates. IPS e.max ZirCAD, In-Ceram alumina, and zirconia CAD/CAM were the most commonly used framework materials. Most studies used air abrasion, salinization, or hydrofluoric acid for surface treatment. Adhesive resin cements were the most frequently used type of cement. The survival rate of In-Ceram ceramics (85.3%-94.8%) was lower than that of In-Ceram zirconia and IPS e.max ZirCAD. Debonding, followed by framework fracture, was the leading cause of failure. Following 3-10 years follow-up, the survival percentage of all-ceramic RBFDPs ranged from 76% to 100%. Although RBFDPs have demonstrated satisfactory success as a conservative treatment, long-term follow-ups and higher sample sizes in clinical research are required to gain more reliable outcomes on the clinical success rate of various RBFDP designs.
{"title":"Full-ceramic resin-bonded fixed dental prostheses: A systematic review.","authors":"Sareh Habibzadeh, Faranak Khamisi, Seyed Ali Mosaddad, Gustavo Vicentis de Oliveira Fernandes, Artak Heboyan","doi":"10.1177/22808000241250118","DOIUrl":"10.1177/22808000241250118","url":null,"abstract":"<p><p>Despite the development of implant-supported prostheses, there are still patients for whom conservative treatments such as resin-bonded fixed dental prostheses (RBFDPs) are more appropriate. This study's objective was to analyze the available research on full-ceramic RBFDPs. In this study, Web of Science, MEDLINE/PubMed, Scopus, Embase, Cochrane Library, and Google Scholar databases were searched for articles published in English between 2010 and 2020. A total of 14 studies were reviewed based on the eligibility criteria. The results showed that using a cantilever design with one abutment had an advantage over two abutments. Additionally, it was proposed that preparations designed with retentive aids, such as a proximal box, groove, and pinhole, could improve RBFDP survival rates. IPS e.max ZirCAD, In-Ceram alumina, and zirconia CAD/CAM were the most commonly used framework materials. Most studies used air abrasion, salinization, or hydrofluoric acid for surface treatment. Adhesive resin cements were the most frequently used type of cement. The survival rate of In-Ceram ceramics (85.3%-94.8%) was lower than that of In-Ceram zirconia and IPS e.max ZirCAD. Debonding, followed by framework fracture, was the leading cause of failure. Following 3-10 years follow-up, the survival percentage of all-ceramic RBFDPs ranged from 76% to 100%. Although RBFDPs have demonstrated satisfactory success as a conservative treatment, long-term follow-ups and higher sample sizes in clinical research are required to gain more reliable outcomes on the clinical success rate of various RBFDP designs.</p>","PeriodicalId":14985,"journal":{"name":"Journal of Applied Biomaterials & Functional Materials","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}