Journal of Investigative and Clinical Dentistry最新文献

{"title":"Effect of oral health behavior and demographic variables on gingival health in 11-16-year-old school children in Chandigarh, India: A cross-sectional study","authors":"Urvashi Sharma,&nbsp;Namrata Gill,&nbsp;Anubha Gulati,&nbsp;Sidhi Passi,&nbsp;Leena Verma,&nbsp;Ikreet S. Bal,&nbsp;Rosy Arora,&nbsp;Archna Agnihotri,&nbsp;Krishan Gauba","doi":"10.1111/jicd.12405","DOIUrl":"10.1111/jicd.12405","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>The aims of the present study were to assess the prevalence and pattern of gingival bleeding on probing (BOP) and to evaluate the effect of oral health behavior and demographic determinants on gingival health in 11-16-year-old school children in Chandigarh, India.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cross-sectional study, using stratified random sampling, was conducted across two age groups, 11-13 years and 14-16 years, and two socioeconomic strata: upper and lower. The World Health Organization (WHO) Oral Health Questionnaire for Children was used to record the data, and the WHO Community Periodontal Index (modified) was used to assess gingival BOP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among all the 2294 children examined, an estimated 54.2% had gingival BOP. The odds of BOP were also higher in the younger age group (odds ratio [OR]: 1.261, 95% confidence interval [CI]: 1.068-1.487, <i>P </i>=<i> </i>0.006), higher for boys (OR: 1.200, 95% CI: 1.017-1.416, <i>P </i>=<i> </i>0.031), and lower in the upper strata (OR: 0.805, 95% CI: 0.682-0.951, <i>P </i>=<i> </i>0.011). Gingival BOP was 58.5% in the mandibular and 41.5% in the maxillary arch (<i>P </i>&lt;<i> </i>0.0001); χ²-test found tooth cleaning frequency to be a significant contributing factor for gingival BOP (<i>P </i>=<i> </i>0.014).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>An inverse co-relation of gingival BOP with age, socioeconomic status, and a higher prevalence in boys was observed, necessitating periodic preventive dental education, particularly focusing on the target group. Additionally, early screening and prompt treatment to intercept the disease is advocated.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16204,"journal":{"name":"Journal of Investigative and Clinical Dentistry","volume":"10 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/jicd.12405","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37042867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of proper or reciprocating optimum torque reverse kinematics on cyclic fatigue of four single files","authors":"Eugenio Pedullà,&nbsp;Emanuele Ambu,&nbsp;Fabio Rovai,&nbsp;Seok-Woo Chang,&nbsp;Federico Campedelli,&nbsp;Giacomo Corsentino,&nbsp;Silvia Rapisarda,&nbsp;Giusy R. M. La Rosa,&nbsp;Simone Grandini","doi":"10.1111/jicd.12409","DOIUrl":"10.1111/jicd.12409","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The aim of the present study was to evaluate the resistance to cyclic fatigue of heat-treated single files used in proper or in reciprocating optimum torque reverse motions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Ninety-six HyFlex electrical discharge machining (EDM), Reciproc R25 (Rec), WaveOne Primary (WO), and WaveOne Gold (WOG) Primary were used. Resistance to cyclic fatigue was determined by recording time to fracture in a stainless steel artificial canal. Differential scanning calorimetric analysis was performed. Data were analyzed by two-way analysis of variance and Bonferroni post-hoc tests at 0.05.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In both movements, HyFlex EDM showed higher time to fracture than other files (<i>P </i>&lt;<i> </i>0.0001). Rec showed higher time to fracture than WO (<i>P </i>&lt;<i> </i>0.0001), while WOG showed higher cyclic fatigue resistance than Rec and WO with both movements (<i>P </i>&lt;<i> </i>0.005).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Reciprocating optimum torque reverse motion improved significantly cyclic fatigue resistance of gold and controlled memory wire single files.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16204,"journal":{"name":"Journal of Investigative and Clinical Dentistry","volume":"10 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/jicd.12409","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37036077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of three different apex locators in determining the working length of mandibular first molar teeth with irreversible pulpitis compared with an intraoral periapical radiograph: A block randomized, controlled, clinical trial","authors":"Sadashivam Vanitha,&nbsp;I. Anand Sherwood","doi":"10.1111/jicd.12408","DOIUrl":"10.1111/jicd.12408","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The aim of the present study was to assess the clinical accuracy APEX and 0.5 marks of three different apex locators – iPex II, Root ZX, and Apex ID – before and after canal preparation in the mandibular first molar.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Sixty patients between the ages of 13-60 years participated in the study. After access gaining and canal preparation stages files were inserted with the apex locator clip attached until the electronic apex locators (EALs) shows readings of APEX and 0.5 marks and same is confirmed with periapical radiographs. Eighteen apex locator readings were recorded from each tooth, and 1080 readings were obtained from the 60 patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Differences among readings from apex locators and radiographic readings were assessed using paired <i>t</i> test. Only in two patients (1 male and 1 female) were the APEX mark readings different from the radiograph estimation. When the 0.5 mark readings of three different EALs were compared with each other, we could observe that the readings from Root ZX differed significantly (<i>P</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In the present study, we observed the negligible differences in readings between the EAL at the APEX mark readings, coinciding with the radiographic observation. Clinically, we recommend the apical foramen be located with the apex locators’ APEX mark readings prior to identifying the apical constriction position.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16204,"journal":{"name":"Journal of Investigative and Clinical Dentistry","volume":"10 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/jicd.12408","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37028469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of waterpipe smoking on peri-implant health: A systematic review and meta-analysis","authors":"Zohaib Akram,&nbsp;Fawad Javed,&nbsp;Fahim Vohra","doi":"10.1111/jicd.12403","DOIUrl":"10.1111/jicd.12403","url":null,"abstract":"<p>The aim of the present review was to evaluate the effect of waterpipe smoking (WS) on clinical peri-implant inflammatory parameters compared to non-smokers (NS) with dental implants. Literature searches were performed using bibliographic databases up to May 2018. Primary outcomes included peri-implant bone loss (PIBL), while secondary outcomes were probing depth (PD), plaque index, and bleeding on probing. Relative risk (RR) and 95% confidence intervals (CI) for each PIBL and PD were estimated by a random-effect model. Four retrospective case-control studies were included in the qualitative and quantitative syntheses. All of the included studies showed statistically-significantly worse peri-implant outcomes in WS compared to NS. Considering the effects of WS on peri-implant parameters, significant heterogeneity for PIBL (<i>Q</i>-value = 34.21, <i>P</i> &lt; 0.0001, <i>I</i>² = 94.16%) and PD (<i>Q</i>-value = 51.97, <i>P</i> &lt; 0.0001, <i>I</i>² = 96.15%) was observed between both groups. The overall RR for PIBL (RR = 3.32, 95% CI = 1.01-3.97, <i>P</i> = 0.001) and PD (RR = 3.40, 95% CI = 1.91-7.17, <i>P</i> = 0.001) were significant between WS and NS groups. WS has detrimental effect on peri-implant health. Clinicians should instruct and advise patients about poor prognosis and peri-implant diseases caused by WS.</p>","PeriodicalId":16204,"journal":{"name":"Journal of Investigative and Clinical Dentistry","volume":"10 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/jicd.12403","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37024026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peri-implantitis risk factors: A prospective evaluation","authors":"Anthony Mazel,&nbsp;Souad Belkacemi,&nbsp;Patrick Tavitian,&nbsp;Grégory Stéphan,&nbsp;Delphine Tardivo,&nbsp;Jean Hugues Catherine,&nbsp;Gérard Aboudharam","doi":"10.1111/jicd.12398","DOIUrl":"10.1111/jicd.12398","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The aim of the present study was to create a tool to evaluate the risk of peri-implantitis according its severity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>After ethics committee approval, 43 patients provided signed consent and were included prospectively. Forty-five observations were recorded. The following criteria were recorded: number of implant faces showing bleeding and/or suppuration, pocket depth on at least two faces of the implant, bone loss as a function of the length of the implant evaluated on X-rays, number of implant faces with bacterial plaque, the parameters required for determination of excess cement (screwed or sealed prosthesis, burying of sealed prostheses), periodontal status, glycemia, and annual consumption of tobacco. Each of these parameters was plotted on a chart using Microsoft Excel.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Seventeen of 45 (37.8%) cases were identified as having high peri-implantitis risk, two of 45 (4.4%) had low risk, and 11 of 45 (24.4%) had moderate risk; 33.3% patients did not have peri-implantitis and were considered at very low risk.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The observed results applied to the evaluation model are an effective diagnostic tool in assessing the risk of peri-implantitis. The tool takes into account parameters, which have not been taken into account until now. The information is automatically processed and allows early management of peri-implantitis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16204,"journal":{"name":"Journal of Investigative and Clinical Dentistry","volume":"10 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/jicd.12398","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36930841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-oral, aerobic, Gram-negative bacilli in the oral cavity of Thai HIV-positive patients on Highly-active anti-retrovirus therapy medication","authors":"Pratanporn Arirachakaran,&nbsp;Sureeat Luangworakhun,&nbsp;Georgios Charalampakis,&nbsp;Gunnar Dahlén","doi":"10.1111/jicd.12387","DOIUrl":"10.1111/jicd.12387","url":null,"abstract":"Abstract In the present study, we identified and evaluated the antibiotic susceptibility of 96 independent, aerobic, Gram‐negative bacillus isolates from 255 Thai HIV‐positive adults who were on Highly‐active anti‐retrovirus therapy (HAART) medication. Another 46 isolates from HIV non‐HAART individuals, vertically transmitted HIV‐positive individuals, and non‐HIV controls were included for comparison. A total of 103 strains were tested for antibiotic susceptibility using disc diffusion for screening and E‐test for minimal inhibitory concentration determination, with special attention on extended‐spectrum beta‐lactamase (ESBL) isolates. Pseudomonas aeruginosa, Pseudomonas luteola, Burkholderia cepacia, Aeromonas hydrophila, Klebsiella, and Enterobacter species were the most common bacteria. All strains were resistant against penicillin, amoxicillin, clindamycin, and metronidazole. No ESBL isolates were found.","PeriodicalId":16204,"journal":{"name":"Journal of Investigative and Clinical Dentistry","volume":"10 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/jicd.12387","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36914849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of a non-fluoridated microcrystalline hydroxyapatite dentifrice on enamel caries progression in highly caries-susceptible orthodontic patients: A randomized, controlled 6-month trial","authors":"Ulrich Schlagenhauf,&nbsp;Karl-Heinz Kunzelmann,&nbsp;Christian Hannig,&nbsp;Theodor W. May,&nbsp;Helmut Hösl,&nbsp;Mario Gratza,&nbsp;Gabriele Viergutz,&nbsp;Marco Nazet,&nbsp;Sebastian Schamberger,&nbsp;Peter Proff","doi":"10.1111/jicd.12399","DOIUrl":"10.1111/jicd.12399","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The aim of the present randomized, controlled trial was to compare the impact of the regular use of a fluoride-free microcrystalline hydroxyapatite (HAP) dentifrice and a 1400 ppm fluoride control dentifrice on caries progression in 150 highly caries-active orthodontic patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The primary outcome was the occurrence of lesions with International Caries Detection and Assessment System (ICDAS) ≥code 1 on the vestibular surfaces of teeth 15-25 within 168 days after fixation of orthodontic brackets. Secondary outcomes were lesion development ICDAS ≥code 2, the plaque index, and the gingival index.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In total, 147 patients were included in the intent-to-treat (ITT) analysis; 133 finished the study per protocol (PP). An increase in enamel caries ICDAS ≥code 1 was observed in 56.8% (ITT) and 54.7% (PP) of the HAP group participants compared with 60.9% (ITT) and 61.6% (PP) of the fluoride control group. Non-inferiority testing (ITT and PP) demonstrated the absence of a significant difference between the groups. No significant differences in secondary outcomes were observed between the groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In highly caries-active patients, the impact of the regular use of a microcrystalline HAP dentifrice on caries progression is not significantly different from the use of a 1400 ppm fluoride toothpaste (ClinicalTrials.gov: NCT02705456).</p>\u0000 </section>\u0000 </div>","PeriodicalId":16204,"journal":{"name":"Journal of Investigative and Clinical Dentistry","volume":"10 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/jicd.12399","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36904104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preventive effects of carbon dioxide laser and casein phosphopeptide amorphous calcium phosphate fluoride varnish on enamel demineralization: A comparative, in vitro study","authors":"Moufida Abufarwa,&nbsp;Amal Noureldin,&nbsp;Taha Azimaie,&nbsp;Phillip M. Campbell,&nbsp;Peter H. Buschang","doi":"10.1111/jicd.12400","DOIUrl":"10.1111/jicd.12400","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The aim of the present study was to compare the effects of carbon dioxide (CO₂) laser and casein phosphopeptide amorphous calcium phosphate (CPP-ACP)fluoride varnish on enamel demineralization.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Human teeth were randomly assigned to three groups. The enamel was treated with fluoride varnish, 10.6 μm CO₂ laser, or no treatment (control), followed by 9 days of pH cycling. Baseline and final FluoreCam images were used to quantify the area, intensity, and impact of demineralization; cross-sectional microhardness was used to measure the mechanical properties of the enamel.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>There were statistically-significant changes in the area, intensity and impact of demineralization in the control and laser groups (<i>P </i>&lt;<i> </i>0.05), but not in the fluoride group. The control group showed a significantly greater area and impact of enamel demineralization compared to the fluoride group. The area of demineralization in the laser group was significantly greater than that of the fluoride group. Enamel demineralization of the laser and control groups was comparable. The fluoride group showed statistically-significant harder enamel than the control at 20, 40, and 60 μm depths; the laser group enamel was significantly harder than the control at 20 and 40 μm depths. The fluoride group showed statistically-significant harder enamel than the laser group at 20 μm depth.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>CPP-ACP fluoride varnish is more effective than CO₂ in preventing enamel demineralization.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16204,"journal":{"name":"Journal of Investigative and Clinical Dentistry","volume":"10 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/jicd.12400","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36896427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unerupted permanent incisors and associated dental anomalies","authors":"Chiewee Tan,&nbsp;Manikandan Ekambaram,&nbsp;Gillian H. M. Lee,&nbsp;Cynthia K. Y. Yiu","doi":"10.1111/jicd.12395","DOIUrl":"10.1111/jicd.12395","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>The aim of the present study was to investigate the association between unerupted permanent incisors and dental anomalies among children and adolescents.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The clinical records of patients between January 2005 and December 2014 were retrieved to identify those with unerupted permanent incisors. A retrospective audit on the presence or absence of any dental anomalies was done from all available records of the included patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 266 patients with 320 unerupted permanent incisors were identified from the 15 987 patients in the study. Among the unerupted permanent incisors, 222 (69.4%) were associated with dental anomalies, which was significantly higher than those showing an absence of dental anomalies (N = 98, 30.6%, <i>P </i>&lt;<i> </i>0.001). For the unerupted maxillary central incisors, a significantly higher proportion was associated with supernumerary teeth (<i>P </i>&lt;<i> </i>0.001). For the unerupted maxillary lateral incisors, a significantly higher proportion was associated with the ectopic eruption of permanent canines when compared with other dental anomalies (<i>P </i>&lt;<i> </i>0.001). The presence of the ectopic eruption of permanent canine, double teeth, and hyperdontia was significantly higher among male patients with unerupted permanent incisors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Unerupted permanent incisors were associated with supernumerary teeth and ectopic eruption of permanent canines. Specifically, a higher proportion of unerupted maxillary central incisors was associated with the presence of supernumerary teeth, whereas a higher percentage of unerupted maxillary lateral incisors was associated with the ectopic eruption of permanent canines.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16204,"journal":{"name":"Journal of Investigative and Clinical Dentistry","volume":"10 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/jicd.12395","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36896425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-inflammatory potential of a carvedilol gel in the pulpal tissue of rats after dental bleaching: A histopathological evaluation","authors":"Lidiane M. Louzada,&nbsp;André L. F. Briso,&nbsp;Francine Benetti,&nbsp;Letícia B. Vieira,&nbsp;Rogério de Castilho Jacinto,&nbsp;Elói Dezan-Júnior,&nbsp;Luciano T. A. Cintra","doi":"10.1111/jicd.12401","DOIUrl":"10.1111/jicd.12401","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Carvedilol is an antioxidant that decreases inflammation in periodontitis. The hydrogen peroxide (H₂O₂) of bleaching gel causes inflammation and necrosis of the dental pulp. In the present study, we evaluated the anti-inflammatory potential of carvedilol in the pulp of rats after bleaching.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The right upper molars of rats received 35% H₂O₂ (1× 30 minutes), and the left upper molars were used as the control. Half of the rats received carvedilol gel (1× 10 minutes), forming the following groups: bleached, bleached followed by carvedilol (bleached+carvedilol), and control. After 2 and 30 days (N = 7 hemi-maxillae/group), the rats were killed for histological evaluation, and statistical tests were performed (<i>P </i>&lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>After 2 days, the bleached group showed necrosis in the occlusal third of the coronal pulp, and in the bleached+carvedilol group, severe inflammation (<i>P </i>&gt; 0.05), both different from the control (<i>P </i>&lt; 0.05). In the middle third, the bleached group showed severe inflammation, and the bleached+carvedilol group showed moderate inflammation (<i>P </i>&gt; 0.05), with the only difference between the bleached and control groups (<i>P </i>&lt; 0.05). In the cervical third, the bleached group showed moderate inflammation, and the bleached+carvedilol group showed mild inflammation (<i>P </i>&gt; 0.05). The difference again was only between the bleached and control groups (<i>P </i>&lt; 0.05). At 30 days, there was no inflammation and a marked amount of tertiary dentin in bleached teeth (<i>P</i> &gt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Carvedilol gel has the potential of minimizing H₂O₂ damage, especially in deep regions of the dental pulp of rats after bleaching.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16204,"journal":{"name":"Journal of Investigative and Clinical Dentistry","volume":"10 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/jicd.12401","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36906941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}