Plant receptor kinases (RKs) are critical for transmembrane signalling involved in various biological processes including plant immunity. MALE DISCOVERER1-INTERACTING RECEPTOR-LIKE KINASE 2 (MIK2) is a unique RK that recognizes a family of immunomodulatory peptides called SERINE-RICH ENDOGENOUS PEPTIDEs (SCOOPs) and activates pattern-triggered immunity responses. However, the precise mechanisms underlying SCOOP recognition and activation of MIK2 remain poorly understood. Here we present the cryogenic electron microscopy structure of a ternary complex consisting of the extracellular leucine-rich repeat (LRR) of MIK2 (MIK2LRR), SCOOP12 and the extracellular LRR of the co-receptor BAK1 (BAK1LRR) at a resolution of 3.34 Å. The structure reveals that a DNHH motif in MIK2LRR plays a critical role in specifically recognizing the highly conserved SxS motif of SCOOP12. Furthermore, the structure demonstrates that N-glycans at MIK2LRRAsn410 directly interact with the N-terminal capping region of BAK1LRR. Mutation of the glycosylation site, MIK2LRRN410D, completely abolishes the SCOOP12-independent interaction between MIK2LRR and BAK1LRR and substantially impairs the assembly of the MIK2LRR–SCOOP12–BAK1LRR complex. Supporting the biological relevance of N410-glycosylation, MIK2N410D substantially compromises SCOOP12-triggered immune responses in plants. Collectively, these findings elucidate the mechanism underlying the loose specificity of SCOOP recognition by MIK2 and reveal an unprecedented mechanism by which N-glycosylation modification of LRR-RK promotes receptor activation. This study demonstrates a crucial role of N-glycosylation in activating a receptor-like kinase by promoting its interaction with co-receptors.
{"title":"N-glycosylation facilitates the activation of a plant cell-surface receptor","authors":"Fangshuai Jia, Yu Xiao, Yaojie Feng, Jinghui Yan, Mingzhu Fan, Yue Sun, Shijia Huang, Weiguo Li, Tian Zhao, Zhifu Han, Shuguo Hou, Jijie Chai","doi":"10.1038/s41477-024-01841-6","DOIUrl":"10.1038/s41477-024-01841-6","url":null,"abstract":"Plant receptor kinases (RKs) are critical for transmembrane signalling involved in various biological processes including plant immunity. MALE DISCOVERER1-INTERACTING RECEPTOR-LIKE KINASE 2 (MIK2) is a unique RK that recognizes a family of immunomodulatory peptides called SERINE-RICH ENDOGENOUS PEPTIDEs (SCOOPs) and activates pattern-triggered immunity responses. However, the precise mechanisms underlying SCOOP recognition and activation of MIK2 remain poorly understood. Here we present the cryogenic electron microscopy structure of a ternary complex consisting of the extracellular leucine-rich repeat (LRR) of MIK2 (MIK2LRR), SCOOP12 and the extracellular LRR of the co-receptor BAK1 (BAK1LRR) at a resolution of 3.34 Å. The structure reveals that a DNHH motif in MIK2LRR plays a critical role in specifically recognizing the highly conserved SxS motif of SCOOP12. Furthermore, the structure demonstrates that N-glycans at MIK2LRRAsn410 directly interact with the N-terminal capping region of BAK1LRR. Mutation of the glycosylation site, MIK2LRRN410D, completely abolishes the SCOOP12-independent interaction between MIK2LRR and BAK1LRR and substantially impairs the assembly of the MIK2LRR–SCOOP12–BAK1LRR complex. Supporting the biological relevance of N410-glycosylation, MIK2N410D substantially compromises SCOOP12-triggered immune responses in plants. Collectively, these findings elucidate the mechanism underlying the loose specificity of SCOOP recognition by MIK2 and reveal an unprecedented mechanism by which N-glycosylation modification of LRR-RK promotes receptor activation. This study demonstrates a crucial role of N-glycosylation in activating a receptor-like kinase by promoting its interaction with co-receptors.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"10 12","pages":"2014-2026"},"PeriodicalIF":15.8,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142594706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-04DOI: 10.1038/s41477-024-01839-0
Ning An, Xiaowei Huang, Zhao Yang, Minhua Zhang, Miaolian Ma, Fang Yu, Lianyan Jing, Boya Du, Yong-Fei Wang, Xue Zhang, Peng Zhang
Jasmonates (JAs) are a class of oxylipin phytohormones including jasmonic acid (JA) and derivatives that regulate plant growth, development and biotic and abiotic stress. A number of transporters have been identified to be responsible for the cellular and subcellular translocation of JAs. However, the mechanistic understanding of how these transporters specifically recognize and transport JAs is scarce. Here we determined the cryogenic electron microscopy structure of JA exporter AtABCG16 in inward-facing apo, JA-bound and occluded conformations, and outward-facing post translocation conformation. AtABCG16 structure forms a homodimer, and each monomer contains a nucleotide-binding domain, a transmembrane domain and an extracellular domain. Structural analyses together with biochemical and plant physiological experiments revealed the molecular mechanism by which AtABCG16 specifically recognizes and transports JA. Structural analyses also revealed that AtABCG16 features a unique bifurcated substrate translocation pathway, which is composed of two independent substrate entrances, two substrate-binding pockets and a shared apoplastic cavity. In addition, residue Phe608 from each monomer is disclosed to function as a gate along the translocation pathway controlling the accessing of substrate JA from the cytoplasm or apoplast. Based on the structural and biochemical analyses, a working model of AtABCG16-mediated JA transport is proposed, which diversifies the molecular mechanisms of ABC transporters. The authors report the cryo-EM structure of JA transporter ABCG16 in multiple conformations. It features a bifurcated translocation pathway, revealing the specific JA binding and transport mechanism that diversifies ABC transporters in higher plants.
茉莉酸（JA）是一类氧化脂素植物激素，包括茉莉酸（JA）及其衍生物，可调节植物的生长、发育以及生物和非生物胁迫。目前已发现一些转运体负责 JA 的细胞和亚细胞转运。然而，人们对这些转运体如何特异性识别和转运 JA 的机理了解甚少。在这里，我们测定了JA转运体AtABCG16的低温电子显微镜结构，包括向内的apo构象、与JA结合的构象和闭锁构象，以及向外的转运后构象。AtABCG16 结构形成一个同源二聚体，每个单体包含一个核苷酸结合结构域、一个跨膜结构域和一个胞外结构域。结构分析以及生化和植物生理实验揭示了 AtABCG16 特异性识别和转运 JA 的分子机制。结构分析还揭示了 AtABCG16 独特的分叉底物转运途径，它由两个独立的底物入口、两个底物结合口袋和一个共享的凋亡腔组成。此外，每个单体的残基 Phe608 被披露为转运途径上的一个门，控制着底物 JA 从细胞质或细胞凋亡体的进入。基于结构和生化分析，提出了 AtABCG16 介导 JA 转运的工作模型，该模型使 ABC 转运体的分子机制多样化。
{"title":"Cryo-EM structure and molecular mechanism of the jasmonic acid transporter ABCG16","authors":"Ning An, Xiaowei Huang, Zhao Yang, Minhua Zhang, Miaolian Ma, Fang Yu, Lianyan Jing, Boya Du, Yong-Fei Wang, Xue Zhang, Peng Zhang","doi":"10.1038/s41477-024-01839-0","DOIUrl":"10.1038/s41477-024-01839-0","url":null,"abstract":"Jasmonates (JAs) are a class of oxylipin phytohormones including jasmonic acid (JA) and derivatives that regulate plant growth, development and biotic and abiotic stress. A number of transporters have been identified to be responsible for the cellular and subcellular translocation of JAs. However, the mechanistic understanding of how these transporters specifically recognize and transport JAs is scarce. Here we determined the cryogenic electron microscopy structure of JA exporter AtABCG16 in inward-facing apo, JA-bound and occluded conformations, and outward-facing post translocation conformation. AtABCG16 structure forms a homodimer, and each monomer contains a nucleotide-binding domain, a transmembrane domain and an extracellular domain. Structural analyses together with biochemical and plant physiological experiments revealed the molecular mechanism by which AtABCG16 specifically recognizes and transports JA. Structural analyses also revealed that AtABCG16 features a unique bifurcated substrate translocation pathway, which is composed of two independent substrate entrances, two substrate-binding pockets and a shared apoplastic cavity. In addition, residue Phe608 from each monomer is disclosed to function as a gate along the translocation pathway controlling the accessing of substrate JA from the cytoplasm or apoplast. Based on the structural and biochemical analyses, a working model of AtABCG16-mediated JA transport is proposed, which diversifies the molecular mechanisms of ABC transporters. The authors report the cryo-EM structure of JA transporter ABCG16 in multiple conformations. It features a bifurcated translocation pathway, revealing the specific JA binding and transport mechanism that diversifies ABC transporters in higher plants.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"10 12","pages":"2052-2061"},"PeriodicalIF":15.8,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-31DOI: 10.1038/s41477-024-01840-7
Keran Zhai, Jack Rhodes, Cyril Zipfel
Plants employ cell-surface receptors to perceive non- or altered-self, including the integrity of their cell wall. Here we identify a specific ligand–receptor module responsive to cell wall damage that potentiates immunity in Arabidopsis. Disruption of cell wall integrity by inhibition of cellulose biosynthesis promotes pattern-triggered immunity transcriptionally in a manner dependent on the receptor kinase MALE DISCOVERER 1-INTERACTING RECEPTOR-LIKE KINASE 2 (MIK2). Notably, while MIK2 can perceive peptides of the large SERINE RICH ENDOGENOUS PEPTIDE family, a single member of this family, SCOOP18, is transcriptionally induced upon cell wall damage and is required for subsequent responses such as lignification and immunity potentiation. Collectively, our results identify the SCOOP18–MIK2 ligand–receptor module as an important central hub, connecting plant cell wall integrity sensing with immunity. The authors identified a specific Arabidopsis ligand–receptor module as a central hub connecting cell wall integrity sensing with pattern-triggered immunity through transcriptional reprogramming.
{"title":"A peptide-receptor module links cell wall integrity sensing to pattern-triggered immunity","authors":"Keran Zhai, Jack Rhodes, Cyril Zipfel","doi":"10.1038/s41477-024-01840-7","DOIUrl":"10.1038/s41477-024-01840-7","url":null,"abstract":"Plants employ cell-surface receptors to perceive non- or altered-self, including the integrity of their cell wall. Here we identify a specific ligand–receptor module responsive to cell wall damage that potentiates immunity in Arabidopsis. Disruption of cell wall integrity by inhibition of cellulose biosynthesis promotes pattern-triggered immunity transcriptionally in a manner dependent on the receptor kinase MALE DISCOVERER 1-INTERACTING RECEPTOR-LIKE KINASE 2 (MIK2). Notably, while MIK2 can perceive peptides of the large SERINE RICH ENDOGENOUS PEPTIDE family, a single member of this family, SCOOP18, is transcriptionally induced upon cell wall damage and is required for subsequent responses such as lignification and immunity potentiation. Collectively, our results identify the SCOOP18–MIK2 ligand–receptor module as an important central hub, connecting plant cell wall integrity sensing with immunity. The authors identified a specific Arabidopsis ligand–receptor module as a central hub connecting cell wall integrity sensing with pattern-triggered immunity through transcriptional reprogramming.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"10 12","pages":"2027-2037"},"PeriodicalIF":15.8,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142555844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-28DOI: 10.1038/s41477-024-01838-1
Hang Zhang, Qian Wang, Noel Blanco-Touriñán, Christian S. Hardtke
Secreted CLAVATA3/EMBRYO SURROUNDING REGION (CLE) peptide ligands dimension the stem cell niche of Arabidopsis shoot meristems by signalling through redundant and cross-compensating CLAVATA1 (CLV1)-type receptor kinases. In the root meristem, the CLV1 homologues BARELY ANY MERISTEM 1 (BAM1) and BAM2 drive CLE13/16-mediated formative divisions that produce the ground tissue layers. Here we report that BAM1/2 are also required to initiate the vascular phloem lineage and that cross-compensation between CLV1-type receptors as observed in the shoot does not operate similarly in the root. Rather, we find that BAM3-mediated CLE45 signalling antagonizes BAM1/2-mediated CLE11/12/13 signalling in the phloem initials but not in the ground tissue. We further observe spatiotemporally contrasting CLE signalling requirements for phloem initiation and differentiation, which are shaped by the SHORT ROOT (SHR) pathway. Our findings thus suggest an intricate quantitative interplay between distinct and antagonistic CLE signalling pathways that organizes tissue layer formation in the Arabidopsis root meristem. The activity of distinct and antagonistic CLE peptide pathways intersects to produce and specify different tissue layers in the Arabidopsis root tip. Their quantitative modulation is required to guide phloem initiation and differentiation.
{"title":"Antagonistic CLE peptide pathways shape root meristem tissue patterning","authors":"Hang Zhang, Qian Wang, Noel Blanco-Touriñán, Christian S. Hardtke","doi":"10.1038/s41477-024-01838-1","DOIUrl":"10.1038/s41477-024-01838-1","url":null,"abstract":"Secreted CLAVATA3/EMBRYO SURROUNDING REGION (CLE) peptide ligands dimension the stem cell niche of Arabidopsis shoot meristems by signalling through redundant and cross-compensating CLAVATA1 (CLV1)-type receptor kinases. In the root meristem, the CLV1 homologues BARELY ANY MERISTEM 1 (BAM1) and BAM2 drive CLE13/16-mediated formative divisions that produce the ground tissue layers. Here we report that BAM1/2 are also required to initiate the vascular phloem lineage and that cross-compensation between CLV1-type receptors as observed in the shoot does not operate similarly in the root. Rather, we find that BAM3-mediated CLE45 signalling antagonizes BAM1/2-mediated CLE11/12/13 signalling in the phloem initials but not in the ground tissue. We further observe spatiotemporally contrasting CLE signalling requirements for phloem initiation and differentiation, which are shaped by the SHORT ROOT (SHR) pathway. Our findings thus suggest an intricate quantitative interplay between distinct and antagonistic CLE signalling pathways that organizes tissue layer formation in the Arabidopsis root meristem. The activity of distinct and antagonistic CLE peptide pathways intersects to produce and specify different tissue layers in the Arabidopsis root tip. Their quantitative modulation is required to guide phloem initiation and differentiation.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"10 12","pages":"1900-1908"},"PeriodicalIF":15.8,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142519524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Astragalus membranaceus has been used in traditional Chinese medicine for over 2,000 years. Its major active triterpenoid saponins, astragalosides, have attracted great attention due to their multiple health benefits and applications in medicine. Despite this, the biosynthetic machinery for astragalosides remains enigmatic. Here a chromosome-level genome assembly of A. membranaceus was generated. The identification of two tailoring enzymes required for astragaloside biosynthesis enabled the discovery of a triterpenoid biosynthetic gene cluster, leading to elucidation of the complete astragaloside biosynthetic pathway. This pathway is characterized by a sequence of selective hydroxylation, epoxidation and glycosylation reactions, which are mediated by three cytochrome P450s, one 2-oxoglutarate-dependent dioxygenase and two glycosyltransferases. Reconstitution of this biosynthetic machinery in Nicotiana benthamiana allowed for heterologous production of astragaloside IV. These findings build a solid foundation for addressing the sourcing issues associated with astragalosides and broaden our understanding of the diversity of terpene biosynthetic gene clusters. Astragaloside IV, the key active compound in Radix Astragali, a medicinal plant used for immunomodulation in Asia and Europe, now has a fully elucidated biosynthetic pathway, enabling its efficient production through synthetic biology.
{"title":"Total biosynthesis of the medicinal triterpenoid saponin astragalosides","authors":"Bingyan Xu, Jian-Ping Huang, Guoqing Peng, Wenying Cao, Zhong Liu, Yin Chen, Jingchun Yao, Yong-Jiang Wang, Jie Li, Guimin Zhang, Shilin Chen, Sheng-Xiong Huang","doi":"10.1038/s41477-024-01827-4","DOIUrl":"10.1038/s41477-024-01827-4","url":null,"abstract":"Astragalus membranaceus has been used in traditional Chinese medicine for over 2,000 years. Its major active triterpenoid saponins, astragalosides, have attracted great attention due to their multiple health benefits and applications in medicine. Despite this, the biosynthetic machinery for astragalosides remains enigmatic. Here a chromosome-level genome assembly of A. membranaceus was generated. The identification of two tailoring enzymes required for astragaloside biosynthesis enabled the discovery of a triterpenoid biosynthetic gene cluster, leading to elucidation of the complete astragaloside biosynthetic pathway. This pathway is characterized by a sequence of selective hydroxylation, epoxidation and glycosylation reactions, which are mediated by three cytochrome P450s, one 2-oxoglutarate-dependent dioxygenase and two glycosyltransferases. Reconstitution of this biosynthetic machinery in Nicotiana benthamiana allowed for heterologous production of astragaloside IV. These findings build a solid foundation for addressing the sourcing issues associated with astragalosides and broaden our understanding of the diversity of terpene biosynthetic gene clusters. Astragaloside IV, the key active compound in Radix Astragali, a medicinal plant used for immunomodulation in Asia and Europe, now has a fully elucidated biosynthetic pathway, enabling its efficient production through synthetic biology.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"10 11","pages":"1826-1837"},"PeriodicalIF":15.8,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142452393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-18DOI: 10.1038/s41477-024-01831-8
Jana Kholová, Milan O. Urban, Miroslava Bavorová, Salvatore Ceccarelli, Lutomia Cosmas, Sabine Desczka, Stefania Grando, Robert Lensink, Eileen Nchanji, Jan Pavlík, Diana Pelaez, Jean-Claude Rubyogo, Louise Sperling, Graham Thiele, Ayat Ullah, Marijn Voorhaar, Erwin Bulte
The development of high-yielding, resilient cultivars is the primary goal of many crop breeding programmes, but the uptake of these new cultivars is persistently low in low-income countries. We discuss constraints related to the adoption of crop cultivars and stress the importance of participatory approaches in building trust and promoting the adoption of new technologies.
{"title":"Promoting new crop cultivars in low-income countries requires a transdisciplinary approach","authors":"Jana Kholová, Milan O. Urban, Miroslava Bavorová, Salvatore Ceccarelli, Lutomia Cosmas, Sabine Desczka, Stefania Grando, Robert Lensink, Eileen Nchanji, Jan Pavlík, Diana Pelaez, Jean-Claude Rubyogo, Louise Sperling, Graham Thiele, Ayat Ullah, Marijn Voorhaar, Erwin Bulte","doi":"10.1038/s41477-024-01831-8","DOIUrl":"10.1038/s41477-024-01831-8","url":null,"abstract":"The development of high-yielding, resilient cultivars is the primary goal of many crop breeding programmes, but the uptake of these new cultivars is persistently low in low-income countries. We discuss constraints related to the adoption of crop cultivars and stress the importance of participatory approaches in building trust and promoting the adoption of new technologies.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"10 11","pages":"1610-1613"},"PeriodicalIF":15.8,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142448153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-18DOI: 10.1038/s41477-024-01834-5
With an increasing ability to understand the complexity of living systems, it becomes more and more evident that well-defined canonical functions of proteins and complexes are intertwined.
{"title":"Non-canonical functions","authors":"","doi":"10.1038/s41477-024-01834-5","DOIUrl":"10.1038/s41477-024-01834-5","url":null,"abstract":"With an increasing ability to understand the complexity of living systems, it becomes more and more evident that well-defined canonical functions of proteins and complexes are intertwined.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"10 10","pages":"1435-1435"},"PeriodicalIF":15.8,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41477-024-01834-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142448101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-18DOI: 10.1038/s41477-024-01826-5
The haplotype-resolved, chromosome-level genome assembly of tetraploid modern rose (Rosa hybrida), along with resequenced genomes of 233 diverse Rosa accessions, enabled the discovery of genetic contributions to the modern rose genome from its ancestral species. These insights into the origin and breeding history of roses open up new avenues for future breeding efforts.
{"title":"Unravelling the complex origin and breeding history of modern roses","authors":"","doi":"10.1038/s41477-024-01826-5","DOIUrl":"10.1038/s41477-024-01826-5","url":null,"abstract":"The haplotype-resolved, chromosome-level genome assembly of tetraploid modern rose (Rosa hybrida), along with resequenced genomes of 233 diverse Rosa accessions, enabled the discovery of genetic contributions to the modern rose genome from its ancestral species. These insights into the origin and breeding history of roses open up new avenues for future breeding efforts.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"10 11","pages":"1621-1622"},"PeriodicalIF":15.8,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142448152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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