首页 > 最新文献

Nature Reviews Physics最新文献

英文 中文
Nature Reviews Physics turns five 自然-物理评论》五周年
IF 38.5 1区 物理与天体物理 Q1 PHYSICS, APPLIED Pub Date : 2024-01-09 DOI: 10.1038/s42254-023-00683-z
As Nature Reviews Physics reaches its fifth birthday, we celebrate just how much high-quality content we have published so far, thanks to our authors, referees, in-house team and readers.
在《自然-物理评论》迎来五周岁生日之际,我们要感谢我们的作者、审稿人、内部团队和读者,庆祝我们迄今为止发表了如此多的高质量内容。
{"title":"Nature Reviews Physics turns five","authors":"","doi":"10.1038/s42254-023-00683-z","DOIUrl":"10.1038/s42254-023-00683-z","url":null,"abstract":"As Nature Reviews Physics reaches its fifth birthday, we celebrate just how much high-quality content we have published so far, thanks to our authors, referees, in-house team and readers.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":"6 1","pages":"1-1"},"PeriodicalIF":38.5,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s42254-023-00683-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139406991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robustness and resilience of complex networks 复杂网络的稳健性和复原力
IF 38.5 1区 物理与天体物理 Q1 PHYSICS, APPLIED Pub Date : 2024-01-08 DOI: 10.1038/s42254-023-00676-y
Oriol Artime, Marco Grassia, Manlio De Domenico, James P. Gleeson, Hernán A. Makse, Giuseppe Mangioni, Matjaž Perc, Filippo Radicchi
Complex networks are ubiquitous: a cell, the human brain, a group of people and the Internet are all examples of interconnected many-body systems characterized by macroscopic properties that cannot be trivially deduced from those of their microscopic constituents. Such systems are exposed to both internal, localized, failures and external disturbances or perturbations. Owing to their interconnected structure, complex systems might be severely degraded, to the point of disintegration or systemic dysfunction. Examples include cascading failures, triggered by an initially localized overload in power systems, and the critical slowing downs of ecosystems which can be driven towards extinction. In recent years, this general phenomenon has been investigated by framing localized and systemic failures in terms of perturbations that can alter the function of a system. We capitalize on this mathematical framework to review theoretical and computational approaches to characterize robustness and resilience of complex networks. We discuss recent approaches to mitigate the impact of perturbations in terms of designing robustness, identifying early-warning signals and adapting responses. In terms of applications, we compare the performance of the state-of-the-art dismantling techniques, highlighting their optimal range of applicability for practical problems, and provide a repository with ready-to-use scripts, a much-needed tool set. Complex biological, social and engineering systems operate through intricate connectivity patterns. Understanding their robustness and resilience against disturbances is crucial for applications. This Review addresses systemic breakdown, cascading failures and potential interventions, highlighting the importance of research at the crossroad of statistical physics and machine learning.
复杂网络无处不在:细胞、人脑、人群和互联网都是相互连接的多体系统的例子,这些系统的宏观特性无法从其微观组成部分的特性中简单推导出来。这些系统既会受到内部局部故障的影响,也会受到外部干扰或扰动的影响。由于其结构相互关联,复杂系统可能会严重退化,以至于解体或系统功能失调。这方面的例子包括电力系统最初局部过载引发的级联故障,以及生态系统的严重衰退可能导致灭绝。近年来,人们通过将局部性和系统性故障归结为可改变系统功能的扰动,对这一普遍现象进行了研究。我们利用这一数学框架,回顾了表征复杂网络鲁棒性和恢复力的理论和计算方法。我们从设计鲁棒性、识别预警信号和调整响应等方面讨论了减轻扰动影响的最新方法。在应用方面,我们比较了最先进的拆解技术的性能,强调了它们对实际问题的最佳适用范围,并提供了一个包含即用脚本的资源库,这是一套急需的工具。
{"title":"Robustness and resilience of complex networks","authors":"Oriol Artime, Marco Grassia, Manlio De Domenico, James P. Gleeson, Hernán A. Makse, Giuseppe Mangioni, Matjaž Perc, Filippo Radicchi","doi":"10.1038/s42254-023-00676-y","DOIUrl":"10.1038/s42254-023-00676-y","url":null,"abstract":"Complex networks are ubiquitous: a cell, the human brain, a group of people and the Internet are all examples of interconnected many-body systems characterized by macroscopic properties that cannot be trivially deduced from those of their microscopic constituents. Such systems are exposed to both internal, localized, failures and external disturbances or perturbations. Owing to their interconnected structure, complex systems might be severely degraded, to the point of disintegration or systemic dysfunction. Examples include cascading failures, triggered by an initially localized overload in power systems, and the critical slowing downs of ecosystems which can be driven towards extinction. In recent years, this general phenomenon has been investigated by framing localized and systemic failures in terms of perturbations that can alter the function of a system. We capitalize on this mathematical framework to review theoretical and computational approaches to characterize robustness and resilience of complex networks. We discuss recent approaches to mitigate the impact of perturbations in terms of designing robustness, identifying early-warning signals and adapting responses. In terms of applications, we compare the performance of the state-of-the-art dismantling techniques, highlighting their optimal range of applicability for practical problems, and provide a repository with ready-to-use scripts, a much-needed tool set. Complex biological, social and engineering systems operate through intricate connectivity patterns. Understanding their robustness and resilience against disturbances is crucial for applications. This Review addresses systemic breakdown, cascading failures and potential interventions, highlighting the importance of research at the crossroad of statistical physics and machine learning.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":"6 2","pages":"114-131"},"PeriodicalIF":38.5,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139422122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Why a culture of brilliance is bad for physics 辉煌文化为何不利于物理学
IF 38.5 1区 物理与天体物理 Q1 PHYSICS, APPLIED Pub Date : 2024-01-08 DOI: 10.1038/s42254-023-00685-x
Melis Muradoglu, Sophie H. Arnold, Aashna Poddar, Adam Stanaland, Duygu Yilmaz, Andrei Cimpian
Women and people of colour are underrepresented in physics in many parts of the world, to the detriment of the field. How do academics’ beliefs about the role of ‘brilliance’ in career success contribute to these representation gaps, and what can be done to address them?
在世界许多地方,女性和有色人种在物理学领域的代表性不足,这对该领域的发展不利。学术界关于 "才华 "在事业成功中的作用的观念是如何造成这些代表性差距的?
{"title":"Why a culture of brilliance is bad for physics","authors":"Melis Muradoglu, Sophie H. Arnold, Aashna Poddar, Adam Stanaland, Duygu Yilmaz, Andrei Cimpian","doi":"10.1038/s42254-023-00685-x","DOIUrl":"10.1038/s42254-023-00685-x","url":null,"abstract":"Women and people of colour are underrepresented in physics in many parts of the world, to the detriment of the field. How do academics’ beliefs about the role of ‘brilliance’ in career success contribute to these representation gaps, and what can be done to address them?","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":"6 2","pages":"75-77"},"PeriodicalIF":38.5,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139396593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Packing finite numbers of spheres efficiently 高效打包有限数量的球体
IF 38.5 1区 物理与天体物理 Q1 PHYSICS, APPLIED Pub Date : 2024-01-08 DOI: 10.1038/s42254-024-00687-3
Zoe Budrikis
A paper in Nature Communications reports experiments and simulations of spherical particles that help show how finite numbers of spheres pack in practice.
自然-通讯》(Nature Communications)上的一篇论文报告了球形粒子的实验和模拟,有助于说明有限数量的球体在实际中是如何包装的。
{"title":"Packing finite numbers of spheres efficiently","authors":"Zoe Budrikis","doi":"10.1038/s42254-024-00687-3","DOIUrl":"10.1038/s42254-024-00687-3","url":null,"abstract":"A paper in Nature Communications reports experiments and simulations of spherical particles that help show how finite numbers of spheres pack in practice.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":"6 2","pages":"82-82"},"PeriodicalIF":38.5,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139398628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Faster Monte Carlo simulations of systems with long-range interactions 对具有长程相互作用的系统进行更快的蒙特卡罗模拟
IF 38.5 1区 物理与天体物理 Q1 PHYSICS, APPLIED Pub Date : 2024-01-08 DOI: 10.1038/s42254-024-00686-4
Zoe Budrikis
A paper in Physical Review X reports a new, faster, algorithm for Metropolis Monte Carlo simulations of systems with long-range interactions.
物理评论 X》上的一篇论文报告了一种新的、更快的 Metropolis 蒙特卡罗模拟算法,用于对具有长程相互作用的系统进行模拟。
{"title":"Faster Monte Carlo simulations of systems with long-range interactions","authors":"Zoe Budrikis","doi":"10.1038/s42254-024-00686-4","DOIUrl":"10.1038/s42254-024-00686-4","url":null,"abstract":"A paper in Physical Review X reports a new, faster, algorithm for Metropolis Monte Carlo simulations of systems with long-range interactions.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":"6 2","pages":"83-83"},"PeriodicalIF":38.5,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139396753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Milky Way shines in high-energy neutrinos 银河闪耀着高能中微子的光芒
IF 38.5 1区 物理与天体物理 Q1 PHYSICS, APPLIED Pub Date : 2023-12-13 DOI: 10.1038/s42254-023-00679-9
M. Bustamante
The most energetic astrophysical sources in the Milky Way, cosmic accelerators capable of producing high-energy cosmic rays, have resisted discovery for over a century. Up to now, astrophysicists sought these sources mainly by scouring the Galaxy for the gamma rays they are expected to emit. In 2023, the IceCube Neutrino Observatory discovered high-energy neutrinos from the Milky Way, inaugurating a tell-tale stream of evidence of cosmic-ray production and interaction in the Galaxy. In 2023, the IceCube Neutrino Observatory discovered high-energy neutrinos from the Milky Way, an important clue towards understanding the origin of high-energy cosmic rays.
银河系中能量最大的天体物理源——能够产生高能宇宙射线的宇宙加速器——一个多世纪以来一直没有被发现。到目前为止,天体物理学家寻找这些源主要是通过在银河系中搜寻它们预计会发射的伽马射线。2023年,冰立方中微子天文台发现了来自银河系的高能中微子,开启了银河系宇宙射线产生和相互作用的证据流。2023年,冰立方中微子天文台发现了来自银河系的高能中微子,这是了解高能宇宙射线起源的重要线索。
{"title":"The Milky Way shines in high-energy neutrinos","authors":"M. Bustamante","doi":"10.1038/s42254-023-00679-9","DOIUrl":"10.1038/s42254-023-00679-9","url":null,"abstract":"The most energetic astrophysical sources in the Milky Way, cosmic accelerators capable of producing high-energy cosmic rays, have resisted discovery for over a century. Up to now, astrophysicists sought these sources mainly by scouring the Galaxy for the gamma rays they are expected to emit. In 2023, the IceCube Neutrino Observatory discovered high-energy neutrinos from the Milky Way, inaugurating a tell-tale stream of evidence of cosmic-ray production and interaction in the Galaxy. In 2023, the IceCube Neutrino Observatory discovered high-energy neutrinos from the Milky Way, an important clue towards understanding the origin of high-energy cosmic rays.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":"6 1","pages":"8-10"},"PeriodicalIF":38.5,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138631233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The physics of 3D printing with light 用光进行 3D 打印的物理学原理
IF 38.5 1区 物理与天体物理 Q1 PHYSICS, APPLIED Pub Date : 2023-12-12 DOI: 10.1038/s42254-023-00671-3
Paul Somers, Alexander Münchinger, Shoji Maruo, Christophe Moser, Xianfan Xu, Martin Wegener
The goal of 3D printing is to realize complex 3D structures by locally adding material in small volume elements called voxels — in contrast to successively subtracting material by etching, milling or machining. This field started with optics-based proposals in the 1970s. Progress has required breakthroughs in physics, chemistry, materials science, laser science and engineering. This Review focuses on the physics underlying optics-based approaches, including interference lithography, tomographic volumetric additive manufacturing, stereolithography, continuous liquid-interface printing, light-sheet printing, parallelized spatiotemporal focusing and (multi-)focus scanning. Light–matter interactions that are discussed include one-photon, two-photon, multi-photon or cascaded nonlinear optical absorption processes for excitation and stimulated-emission depletion or excited-state absorption followed by reverse intersystem crossing for de-excitation. The future physics challenges lie in further boosting three metrics: spatial resolution, rate of voxel creation and range of available dissimilar material properties. Engineering challenges lie in achieving these metrics in compact, low-cost and low-energy-consumption instruments and in identifying new applications. This Review categorizes the physics of many different light-based 3D printing modalities and expounds on the light–matter interactions required for the creation of (multi-)material 3D structures. An outlook is provided regarding key printing performance parameters and future directions.
三维打印的目标是通过在称为体素的小体积元素中局部添加材料来实现复杂的三维结构,而不是通过蚀刻、铣削或机械加工来连续减去材料。这一领域始于 20 世纪 70 年代基于光学的提议。要取得进展,需要在物理学、化学、材料科学、激光科学和工程学方面取得突破。本综述重点介绍基于光学的方法的基础物理学,包括干涉光刻、层析体积增材制造、立体光刻、连续液面打印、光片打印、并行时空聚焦和(多)聚焦扫描。讨论的光物质相互作用包括单光子、双光子、多光子或级联非线性光吸收激发过程,以及受激发射耗竭或激发态吸收后的反向系统间交叉去激发过程。未来的物理学挑战在于进一步提高三项指标:空间分辨率、体素创建率和可用的不同材料特性范围。工程学方面的挑战在于如何在结构紧凑、低成本和低能耗的仪器中实现这些指标,以及如何确定新的应用。
{"title":"The physics of 3D printing with light","authors":"Paul Somers, Alexander Münchinger, Shoji Maruo, Christophe Moser, Xianfan Xu, Martin Wegener","doi":"10.1038/s42254-023-00671-3","DOIUrl":"10.1038/s42254-023-00671-3","url":null,"abstract":"The goal of 3D printing is to realize complex 3D structures by locally adding material in small volume elements called voxels — in contrast to successively subtracting material by etching, milling or machining. This field started with optics-based proposals in the 1970s. Progress has required breakthroughs in physics, chemistry, materials science, laser science and engineering. This Review focuses on the physics underlying optics-based approaches, including interference lithography, tomographic volumetric additive manufacturing, stereolithography, continuous liquid-interface printing, light-sheet printing, parallelized spatiotemporal focusing and (multi-)focus scanning. Light–matter interactions that are discussed include one-photon, two-photon, multi-photon or cascaded nonlinear optical absorption processes for excitation and stimulated-emission depletion or excited-state absorption followed by reverse intersystem crossing for de-excitation. The future physics challenges lie in further boosting three metrics: spatial resolution, rate of voxel creation and range of available dissimilar material properties. Engineering challenges lie in achieving these metrics in compact, low-cost and low-energy-consumption instruments and in identifying new applications. This Review categorizes the physics of many different light-based 3D printing modalities and expounds on the light–matter interactions required for the creation of (multi-)material 3D structures. An outlook is provided regarding key printing performance parameters and future directions.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":"6 2","pages":"99-113"},"PeriodicalIF":38.5,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138576372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The quest for superheavy elements and the limit of the periodic table 寻找超重元素和元素周期表的极限
IF 38.5 1区 物理与天体物理 Q1 PHYSICS, APPLIED Pub Date : 2023-12-11 DOI: 10.1038/s42254-023-00668-y
Odile R. Smits, Christoph E. Düllmann, Paul Indelicato, Witold Nazarewicz, Peter Schwerdtfeger
The borders of the periodic table of the elements and of the chart of nuclides are not set in stone. The desire to explore the properties of atoms and their nuclei in a regime of very large numbers of electrons, protons and neutrons has motivated new experimental facilities to create new elements and nuclides at the limits of atomic number and mass. But the small production rates and short lifetimes of superheavy nuclei and their atoms mean that ‘atom-at-a-time’ studies are the only experimental way to probe them. The physical and chemical data obtained so far, augmented by theoretical calculations, indicate significant deviations from extrapolations from lighter elements and isotopes. This situation raises the following question: how much further can one push the limits of the periodic table? In this Review, we describe the major challenges in the field of the superheavy elements and speculate about future directions. Advances in superheavy element studies providing insight into the nuclear and atomic structure and the chemical behaviour of these exotic short-lived systems will help push to the limit of the periodic table of elements and revise the concept of the island of stability.
元素周期表和核素表的边界并不是一成不变的。在电子、质子和中子数量非常大的情况下,人们希望探索原子及其原子核的特性,这促使新的实验设备在原子序数和质量的极限上创造新元素和新核素。但是,超重原子核及其原子的生产率小、寿命短,这意味着 "一次原子 "研究是探测它们的唯一实验方法。迄今为止获得的物理和化学数据以及理论计算结果都表明,这些数据与轻元素和同位素的推断结果有很大偏差。这种情况提出了以下问题:我们还能把元素周期表的极限推得多远?在这篇综述中,我们将描述超重元素领域的主要挑战,并推测未来的发展方向。
{"title":"The quest for superheavy elements and the limit of the periodic table","authors":"Odile R. Smits, Christoph E. Düllmann, Paul Indelicato, Witold Nazarewicz, Peter Schwerdtfeger","doi":"10.1038/s42254-023-00668-y","DOIUrl":"10.1038/s42254-023-00668-y","url":null,"abstract":"The borders of the periodic table of the elements and of the chart of nuclides are not set in stone. The desire to explore the properties of atoms and their nuclei in a regime of very large numbers of electrons, protons and neutrons has motivated new experimental facilities to create new elements and nuclides at the limits of atomic number and mass. But the small production rates and short lifetimes of superheavy nuclei and their atoms mean that ‘atom-at-a-time’ studies are the only experimental way to probe them. The physical and chemical data obtained so far, augmented by theoretical calculations, indicate significant deviations from extrapolations from lighter elements and isotopes. This situation raises the following question: how much further can one push the limits of the periodic table? In this Review, we describe the major challenges in the field of the superheavy elements and speculate about future directions. Advances in superheavy element studies providing insight into the nuclear and atomic structure and the chemical behaviour of these exotic short-lived systems will help push to the limit of the periodic table of elements and revise the concept of the island of stability.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":"6 2","pages":"86-98"},"PeriodicalIF":38.5,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138576578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphogenesis beyond in vivo 超越体内的形态发生
IF 38.5 1区 物理与天体物理 Q1 PHYSICS, APPLIED Pub Date : 2023-12-11 DOI: 10.1038/s42254-023-00669-x
Yue Liu, Xufeng Xue, Shiyu Sun, Norio Kobayashi, Yung Su Kim, Jianping Fu
Morphogenetic events during development shape the body plan and establish structural foundations for tissue forms and functions. Acquiring spatiotemporal information of development, especially for humans, is limited by technical and ethical constraints. Thus, both stem cell-based, in vitro development models and theoretical models have been constructed to recapitulate morphogenetic events during development. These in vitro experimental and theoretical models offer accessibility, efficiency and modulability. However, their physiological relevance often remains obscure, owing to their simplistic nature, which obstructs their applicability as faithful and predictive models of natural development. We examine existing in vitro experimental and theoretical models of various developmental events and compare them with the current knowledge of natural development, with particular considerations of biomechanical driving forces and stereotypic morphogenetic features. We highlight state-of-the-art methods used to construct these in vitro models and emphasize the biomechanical and biophysical principles these models have helped unveil. We also discuss challenges faced by the current in vitro experimental and theoretical models and propose how theoretical modelling and in vitro experimental models should be combined with in vivo studies to advance fundamental understanding of development. Beyond in vivo models, stem cell-based in vitro models and theoretical models of morphogenesis have been constructed to recapitulate morphogenetic events during embryo development with heightened quantitative specificity. This Review discusses the accomplishments, challenges and opportunities of these models in promoting knowledge of mammalian development, including human development.
发育过程中的形态发生塑造了身体的结构,并为组织的形态和功能奠定了结构基础。获取发育的时空信息,特别是人类发育的时空信息,受到技术和伦理的限制。因此,人们构建了基于干细胞的体外发育模型和理论模型,以重现发育过程中的形态发生事件。这些体外实验和理论模型具有易用性、高效性和可调控性。然而,由于其简单性,它们的生理相关性往往仍然模糊不清,这阻碍了它们作为自然发育的忠实和预测模型的适用性。我们研究了各种发育事件的现有体外实验和理论模型,并将它们与当前的自然发育知识进行了比较,特别考虑了生物力学驱动力和定型形态发生特征。我们重点介绍了用于构建这些体外模型的最先进方法,并强调了这些模型有助于揭示的生物力学和生物物理学原理。我们还讨论了当前体外实验和理论模型所面临的挑战,并提出理论建模和体外实验模型应如何与体内研究相结合,以推进对发育的基本认识。
{"title":"Morphogenesis beyond in vivo","authors":"Yue Liu, Xufeng Xue, Shiyu Sun, Norio Kobayashi, Yung Su Kim, Jianping Fu","doi":"10.1038/s42254-023-00669-x","DOIUrl":"10.1038/s42254-023-00669-x","url":null,"abstract":"Morphogenetic events during development shape the body plan and establish structural foundations for tissue forms and functions. Acquiring spatiotemporal information of development, especially for humans, is limited by technical and ethical constraints. Thus, both stem cell-based, in vitro development models and theoretical models have been constructed to recapitulate morphogenetic events during development. These in vitro experimental and theoretical models offer accessibility, efficiency and modulability. However, their physiological relevance often remains obscure, owing to their simplistic nature, which obstructs their applicability as faithful and predictive models of natural development. We examine existing in vitro experimental and theoretical models of various developmental events and compare them with the current knowledge of natural development, with particular considerations of biomechanical driving forces and stereotypic morphogenetic features. We highlight state-of-the-art methods used to construct these in vitro models and emphasize the biomechanical and biophysical principles these models have helped unveil. We also discuss challenges faced by the current in vitro experimental and theoretical models and propose how theoretical modelling and in vitro experimental models should be combined with in vivo studies to advance fundamental understanding of development. Beyond in vivo models, stem cell-based in vitro models and theoretical models of morphogenesis have been constructed to recapitulate morphogenetic events during embryo development with heightened quantitative specificity. This Review discusses the accomplishments, challenges and opportunities of these models in promoting knowledge of mammalian development, including human development.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":"6 1","pages":"28-44"},"PeriodicalIF":38.5,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138576583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A survey on the complexity of learning quantum states 量子态学习复杂性调查
IF 38.5 1区 物理与天体物理 Q1 PHYSICS, APPLIED Pub Date : 2023-12-11 DOI: 10.1038/s42254-023-00662-4
Anurag Anshu, Srinivasan Arunachalam
Quantum learning theory is a new and very active area of research at the intersection of quantum computing and machine learning. Important breakthroughs in the past two years have rapidly solidified its foundations and led to a need for an encompassing survey that can be read by seasoned and early-career researchers in quantum computing. In this Perspective, we survey various results that rigorously study the complexity of learning quantum states. These include progress on quantum tomography, learning physical quantum states, alternative learning models to tomography, and learning classical functions encoded as quantum states. We highlight how these results are leading towards a successful theory with a range of exciting open questions, some of which we list throughout the text. Quantum learning theory is a new and very active area of research at the intersection of quantum computing and machine learning. This Perspective surveys the progress in this field, highlighting a number of exciting open questions.
量子学习理论是量子计算和机器学习交叉的一个新的非常活跃的研究领域。过去两年的重大突破迅速巩固了它的基础,并导致需要一个全面的调查,可以由量子计算领域经验丰富和早期职业的研究人员阅读。从这个角度来看,我们调查了严格研究学习量子态复杂性的各种结果。其中包括量子层析成像、学习物理量子态、层析成像的替代学习模型以及学习编码为量子态的经典函数的进展。我们强调这些结果是如何导致一个成功的理论与一系列令人兴奋的开放性问题,其中一些我们在整个文本中列出。
{"title":"A survey on the complexity of learning quantum states","authors":"Anurag Anshu, Srinivasan Arunachalam","doi":"10.1038/s42254-023-00662-4","DOIUrl":"10.1038/s42254-023-00662-4","url":null,"abstract":"Quantum learning theory is a new and very active area of research at the intersection of quantum computing and machine learning. Important breakthroughs in the past two years have rapidly solidified its foundations and led to a need for an encompassing survey that can be read by seasoned and early-career researchers in quantum computing. In this Perspective, we survey various results that rigorously study the complexity of learning quantum states. These include progress on quantum tomography, learning physical quantum states, alternative learning models to tomography, and learning classical functions encoded as quantum states. We highlight how these results are leading towards a successful theory with a range of exciting open questions, some of which we list throughout the text. Quantum learning theory is a new and very active area of research at the intersection of quantum computing and machine learning. This Perspective surveys the progress in this field, highlighting a number of exciting open questions.","PeriodicalId":19024,"journal":{"name":"Nature Reviews Physics","volume":"6 1","pages":"59-69"},"PeriodicalIF":38.5,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138631229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Nature Reviews Physics
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1