Pediatric Dental Journal最新文献_第9页

Concentrations of interleukin-32, interleukin −10, interleukin −6, and TNF-alfa are higher in saliva of children with early childhood caries 早期儿童龋齿患者唾液中白细胞介素-32、白细胞介素- 10、白细胞介素- 6和tnf - α的浓度较高

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Pediatric Dental Journal

Pub Date : 2023-08-01 DOI: 10.1016/j.pdj.2023.03.005

Ecem Gur , Sultan Keles , Ozge Cevik

Aim

To investigate if the levels of interleukin-32 (IL-32), interleukin-10 (IL-10), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) in the saliva are associated with early childhood caries.

Methods

A total of 56 patients aged between 36 and 71 months with dental caries and without caries were included in this study. The patients’ caries status was evaluated according to the dmft and dmfs indices. IL-32, IL-10, IL-6, and TNF-α levels in the saliva samples of the patients were measured by ELISA.

Results

There were no statistically significant differences in the oral hygiene and nutritional habits, plaque index, and gingival index values between the ECC and control groups evaluated in the study (p > 0.05). The ECC group's salivary IL-32, IL-10, IL-6, and TNF-α levels were statistically significantly higher than the control group (p < 0.001).

Conclusion

The high levels of IL-32, IL-10, IL-6, and TNF-α detected in the saliva of children with ECC reveal that these cytokines may play a potential role in ECC pathogenesis. Salivary levels of IL-32, IL-10, IL-6, and TNF-α are associated with early childhood caries in children.

目的探讨唾液中白细胞介素-32 (IL-32)、白细胞介素-10 (IL-10)、白细胞介素-6 (IL-6)和肿瘤坏死因子-α (TNF-α)水平与儿童早期龋齿的关系。方法选取36 ~ 71月龄有龋和无龋患者56例。根据dmft和dmfs指数评价患者的龋病状况。采用ELISA法检测患者唾液中IL-32、IL-10、IL-6、TNF-α水平。结果ECC组与对照组在口腔卫生和营养习惯、菌斑指数、牙龈指数等方面差异均无统计学意义(p >0.05)。ECC组唾液IL-32、IL-10、IL-6、TNF-α水平均显著高于对照组(p <0.001)。结论ECC患儿唾液中IL-32、IL-10、IL-6、TNF-α水平较高，提示这些细胞因子可能在ECC发病过程中发挥潜在作用。唾液中IL-32、IL-10、IL-6和TNF-α水平与儿童早期龋齿相关。

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引用次数: 0

Single-cell RNA-sequence of dental epithelium reveals responsible genes of dental anomalies in human 人牙上皮单细胞rna序列揭示牙畸形的相关基因

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Pediatric Dental Journal

Pub Date : 2023-08-01 DOI: 10.1016/j.pdj.2023.03.004

Kifu Miyata , Yuta Chiba , Triana Marchelina , Saori Inada , Sae Oka , Kan Saito , Aya Yamada , Satoshi Fukumoto

Objectives

Dental anomalies show various symptoms and some of them are accompanied with inherited diseases. However, only a few of responsible genes of dental anomalies are identified. In this study, we aimed to establish a novel strategy for identification of responsible genes of dental anomalies using integration of single-cell RNA-sequence (scRNA-seq) and Online Mendelian Inheritance in Man (OMIM).

Materials and methods

Single cells were isolated from mandibular incisor of post-natal day (P) seven mice and scRNA-seq were performed. Top 20 differentially expressed genes between clusters were identified and used for further analyses. Inherited diseases of differentially expressed genes and their Clinical Synopsis were examined using OMIM.

Results

The prevalence of inherited disease was 43/80 genes (53.8%) and inherited diseases which associate with dental anomalies were 34/96 diseases (35.4%); 14.6% in enamel abnormality, 4.1% in dentin abnormality, and 16.7% in other abnormality. The prevalence of enamel abnormality was the highest in ameloblast, while that of other abnormality was high in non-ameloblast cell types. Chromosomal mapping of differentially expressed genes indicated that chromosome 4 has “hotspots” of dental anomalies-associated genes.

Conclusion

The differentially expressed genes in dental epithelial cells were responsible for inherited disease which shows dental anomalies. The strategy employed in this study will contribute to identify the responsible gene for dental anomalies.

目的牙畸形表现为多种症状，有的伴有遗传性疾病。然而，只有少数负责基因的牙齿异常被确定。在这项研究中，我们旨在通过整合单细胞rna序列(scRNA-seq)和人类在线孟德尔遗传(OMIM)，建立一种鉴定牙齿异常相关基因的新策略。材料和方法从出生日(P) 7只小鼠的下颌切牙中分离单细胞，进行scrna测序。鉴定出集群间差异表达最多的20个基因，并用于进一步分析。应用OMIM对差异表达基因遗传病进行了临床分析。结果遗传疾病患病率为43/80个(53.8%)，与牙畸形相关的遗传疾病患病率为34/96个(35.4%);牙本质异常14.6%，牙本质异常4.1%，其他异常16.7%。釉质异常发生率以成釉细胞最高，其他异常发生率在非成釉细胞中较高。差异表达基因的染色体定位表明，4号染色体上存在牙齿异常相关基因的“热点”。结论牙上皮细胞差异表达基因是导致牙畸形的遗传疾病的主要原因。本研究采用的策略将有助于确定牙齿异常的负责基因。

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引用次数: 0

Evaluation of antibacterial efficacy of ultrasonic-activated and inactivated chlorhexidine (solution and gel) in infected root canals of primary anterior teeth 超声激活和灭活氯己定（溶液和凝胶）对原发性前牙感染根管的抗菌效果评价

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Pediatric Dental Journal

Pub Date : 2023-08-01 DOI: 10.1016/j.pdj.2023.03.003

Rahaf Kharsa , Mohanad Laflouf , Taissir Albouni , Hasan Alzoubi

Objectives

Sodium hypochlorite is not able to completely eliminate Enterococcus faecalis inside root canals. Therefore, this study aimed to evaluate chlorhexidine gel and solution in eliminating bacterial counts within infected root canals of primary anterior teeth.

Materials and methods

This study included 75 primary anterior teeth in 27 healthy children and it was divided into five groups: Group 1: Chlorhexidine 2% solution, Group 2: Chlorhexidine 2% solution activated by ultrasonic, Group 3: Chlorhexidine 2% gel, Group 4: Chlorhexidine 2% gel activated by ultrasonic, and Group 5: Sodium hypochlorite solution 5.25%. The preliminary smear for bacterial study (S1) was taken before irrigation. The root canals were irrigated in a quantity of 7 ml using a 31-gauge irrigation needle, and irrigant activation was 2 cycles (20 s). The final smear for bacterial study (S2) was taken after irrigation.

Results

There were no statistically differences in the mean percentage change in the decimal logarithm of the anaerobic bacterial colony count, but statistically differences were found for aerobic bacteria. For aerobic bacteria: CHx 2% solution activated better than CHx 2% and NaOCl 5.25% solutions, CHx 2% gel better than CHx 2% solution, CHx 2% gel activated better than CHx 2% and NaOCl 5.25% solutions.

Conclusion

All irrigation solutions used are effective in eliminating bacterial counts in infected primary canals. Chlorhexidine (solution and gel) can be considered a good alternative to sodium hypochlorite in irrigation root canals of primary teeth.

目的:次氯酸钠不能完全清除根管内的粪肠球菌。因此，本研究旨在评价氯己定凝胶和溶液在消除原牙感染根管内细菌计数方面的作用。材料与方法选取27例健康儿童的75颗乳牙，分为5组:1组2%氯己定溶液，2组2%超声活化氯己定溶液，3组2%氯己定凝胶，4组2%超声活化氯己定凝胶，5组5.25%次氯酸钠溶液。冲洗前进行细菌初步涂片检查(S1)。用31号灌洗针灌洗根管，灌洗量为7 ml，灌洗激活2个周期(20 s)。灌洗后进行最后的细菌涂片(S2)。结果两组间厌氧菌菌落计数小数对数的平均变化百分比差异无统计学意义，而好氧菌菌落计数的变化百分比差异有统计学意义。对好氧菌:CHx 2%溶液活化优于CHx 2%和NaOCl 5.25%溶液，CHx 2%凝胶活化优于CHx 2%溶液，CHx 2%凝胶活化优于CHx 2%和NaOCl 5.25%溶液。结论所有冲洗液均能有效清除感染根管的细菌计数。氯己定(溶液和凝胶)是替代次氯酸钠用于乳牙根管冲洗的好方法。

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引用次数: 0

Two cases of ectodermal dysplasia diagnosed based on congenital absence of multiple teeth 以先天性多牙缺失诊断外胚层发育不良2例

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Pediatric Dental Journal

Pub Date : 2023-08-01 DOI: 10.1016/j.pdj.2023.03.001

Rina Kariya, Tamami Kadota, Rena Okawa, Marin Ochiai, Makoto Okuda, Kazuhiko Nakano

Background

Ectodermal dysplasia (ED) is a hereditary disease that affects tissues of the ectoderm system. Some patients reach adulthood before being diagnosed with ED, with dental manifestations sometimes leading to diagnosis.

Case presentation

Two child patients were diagnosed with ED based on dental findings. In one case, partial anodontia of primary and permanent teeth was observed. In the other, the number of primary teeth was normal, while there were only five permanent teeth present.

Conclusion

For some cases of ED not yet diagnosed, dental findings can lead to such a determination.

背景:dectodermal dysplasia (ED)是一种影响外胚层系统组织的遗传性疾病。有些患者在成年后才被诊断为ED，有时会有牙齿表现导致诊断。病例介绍:两名儿童患者根据牙科检查结果被诊断为ED。1例出现乳牙和恒牙的部分畸形。另一组的乳牙数目正常，只有五颗恒牙。结论对于一些尚未确诊的ED病例，牙科检查结果可作为诊断的依据。

引用次数: 0

The correlation between the inner canthal distance and maxillary mesiodens in children 儿童内眼角距离与上颌近中位的相关性

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Pediatric Dental Journal

Pub Date : 2023-08-01 DOI: 10.1016/j.pdj.2023.04.001

Manami Tadano , Yasunori Matsunaga , Kan Saito , Yuria Suzuki , Tomoaki Nakamura , Seira Hoshikawa , Mitsuki Chiba , Ryoko Hino , Yuriko Maruya , Emiko Fukumoto , Aya Yamada , Satoshi Fukumoto

Purpose

This study was conducted to explore the possibility of detecting the presence of impacted teeth in the upper midline using facial morphometric measurements.

Materials and Methods

The study included 260 children, aged 2–13 years, who visited our university hospital. To measure facial morphology, facial photographs were taken along with a ruler, and the correlation between each facial measurement point and the presence of mesiodens was statistically analyzed.

Results

Each measurement point increased in a time-dependent manner and there was a correlation between age and distance. In contrast, the ratio of the inner-canthal distance to the outer-canthal distance was not associated with age. Moreover, an increase in this ratio suggested the possible presence of mesiodens. Since age is associated with the presence of mesiodens within the inner canthal distance, a multivariate analysis that considered the effects of age and sex was performed and showed that the inner canthus/outer canthus ratio was 0.45. When the odds ratio of the presence of mesiodens in the group of less than 1.0 was set to 1.0, the odds ratio of the group of 0.45 or more was 5.36.

Conclusion

The presence of mesiodens can be predicted by measuring the ratio of the inner canthal distance to the outer canthal distance.

目的探讨利用面部形态测量技术检测上中线埋伏牙的可能性。材料与方法研究对象为260例来我院医院就诊的2 ~ 13岁儿童。在测量面部形态时，使用尺子拍摄面部照片，并统计分析每个面部测点与中碘存在的相关性。结果各测点随时间增加，年龄与距离相关。相比之下，内眦距离与外眦距离的比值与年龄无关。此外，这一比例的增加表明可能存在中碘酸盐。由于年龄与内眦距离内中眦赘生物的存在有关，因此进行了考虑年龄和性别影响的多变量分析，结果显示内眦/外眦比为0.45。将小于1.0组中存在的优势比设为1.0，则大于等于0.45组的优势比为5.36。结论通过测量内眦距离与外眦距离的比值，可以预测中眦赘生物的存在。

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引用次数: 0

Evaluation agreement between peer assessors, supervisors, and parents in assessing communication and interpersonal skills of students of pediatric dentistry 同行评估员、主管和家长在评估儿童牙科学生沟通和人际交往技能方面的评估协议

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Pediatric Dental Journal

Pub Date : 2023-08-01 DOI: 10.1016/j.pdj.2023.04.002

Jin Asari, Maiko Fujita-Ohtani, Kuniomi Nakamura, Tomomi Nakamura, Yoshinori Inoue, Shigenari Kimoto

Purpose

Clear and effective communication is crucial for pediatric dentistry practitioners. This study aimed to assess whether evaluations of the communication skills of dental students by supervising physicians, paired students, and patients' parents aligned with the students’ self-evaluations.

Methods

This study was conducted between April and December 2018 at the University Hospital Pediatric Dentistry Outpatient Department. The subjects were 58 pediatric dentistry students (45 male and 13 female students), who were evaluated by their supervising physicians, colleagues, parents, as well as themselves using a questionnaire. The data were analyzed by weighted kappa analysis using SPSS version 27.0 software.

Results

Most supervising physicians, colleagues, and parents rated parameters, such as volume of voice during explanation, explanation of cleaning conditions, and explanation of cleaning equipment as excellent or good. However, many students self-assessed these parameters as below-average. Regarding the consistency between self- and others’ evaluations, only “explanation on snacking, eating or drinking was easy to understand” was generally consistent with the evaluations of supervising physicians.

Conclusions

The study's findings highlighted the importance of reflecting the gap between one's own assessment and that of other evaluators, which would help in the practice or professional decision making of dental students.

目的清晰有效的沟通对儿科牙医从业者至关重要。本研究旨在探讨由督导医师、配对学生和患者家长对牙科学生沟通技巧的评价是否与学生的自我评价一致。方法本研究于2018年4月至12月在大学医院儿科牙科门诊进行。研究对象为58名儿童牙科专业学生(男45名，女13名)，由其指导医师、同事、家长及自己进行问卷调查。采用SPSS 27.0软件对数据进行加权kappa分析。结果大多数督导医师、同事和家长对讲解时的音量、讲解清洁条件、讲解清洁设备等参数评价为优或良。然而，许多学生自我评估这些参数低于平均水平。在自我评价与他人评价的一致性方面，只有“关于零食、饮食的解释容易理解”与督导医生的评价基本一致。结论本研究结果强调了反映自身评估与他人评估之间差距的重要性，这将有助于牙科学生的实践或专业决策。

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引用次数: 0

Comparison of dental health status in children with autism spectrum disorder vs other developmental disabilities: Results from 2016 national survey of Children's health 自闭症谱系障碍儿童与其他发育障碍儿童牙齿健康状况的比较:2016年全国儿童健康调查结果

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Pediatric Dental Journal

Pub Date : 2023-08-01 DOI: 10.1016/j.pdj.2023.03.002

Aiswarya Bulusu , Sean D. Cleary

Introduction

Children with autism spectrum disorder exhibit unconventional responses to sensory stimulation which maybe a barrier to regular dental care.

Clinical Relevance/Objectives

The primary objective of this study is to assess the overall dental health status of children diagnosed with autism spectrum disorder aged 3–17 years compared with children of similar age who were diagnosed with Other Developmental Disabilities.

Methods

Data from 2016 National Survey of Children's Health was used to compare the dental health status of children aged 3–17 years diagnosed with autism spectrum disorder to other developmental disabilities, as well as across the levels of intellectual deficit by employing observational study design.

Results

Results indicated that with a comorbid intellectual deficit, children with autism spectrum disorder have higher odds of lacking preventive oral care and exhibiting dental problems, but significantly lower odds of reporting a poor/fair oral hygiene index compared to children with other developmental disabilities with intellectual deficit. Children with intellectual deficit had higher odds of reporting a poor/fair oral hygiene index but had lower odds of having dental problems compared to children without intellectual deficit, independent of autism spectrum disorder or other developmental disability.

Conclusion

These findings support the development of preventive protocols to improve oral health in children with autism spectrum disorder that may positively impact their quality of life.

患有自闭症谱系障碍的儿童对感官刺激表现出不同寻常的反应，这可能是常规牙科护理的障碍。临床意义/目的本研究的主要目的是评估3-17岁被诊断为自闭症谱系障碍的儿童与被诊断为其他发育障碍的同龄儿童的牙齿健康状况。方法采用观察性研究设计，采用2016年全国儿童健康调查数据，比较3-17岁诊断为自闭症谱系障碍儿童与其他发育障碍儿童以及不同智力缺陷水平儿童的牙齿健康状况。结果与其他发育障碍伴智力缺陷儿童相比，伴有智力缺陷的自闭症谱系障碍儿童缺乏预防性口腔护理和出现牙齿问题的几率更高，但报告口腔卫生指数差/一般的几率显著低于其他发育障碍伴智力缺陷儿童。与没有智力缺陷的儿童相比，有智力缺陷的儿童报告口腔卫生指数差/一般的几率更高，但患牙齿问题的几率更低，这与自闭症谱系障碍或其他发育障碍无关。结论本研究结果支持制定预防方案以改善自闭症谱系障碍儿童的口腔健康，并可能对其生活质量产生积极影响。

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引用次数: 0

Eruption cyst caused by congenital tooth in low birth weight infant 低出生体重儿先天性牙齿引起的剥脱囊肿

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Pediatric Dental Journal

Pub Date : 2023-07-14 DOI: 10.1016/j.pdj.2023.06.004

Eri Yoshida, Kana Goto, Daiki Matsuoka, Yukiko Miyai, Haruka Asaumi, Keiko Tabata, Shuhei Naka, Michiyo Matsumoto-Nakano

Background

Low birth weight is defined as less than 2500 g, with premature birth, a live birth within 37 weeks of pregnancy, and fetal growth restriction the most common causes. Congenital (natal) teeth are teeth that have already erupted at birth, and may be primary or supernumerary teeth.

Case report

A low birth weight infant was suspected to have congenital epulis an eruption cyst in the mandibular central incisor region. At a two-months checkup, gingival alveolar ridge swelling had disappeared and two mandibular anterior teeth were found erupted at the same site. The diagnosis was eruption cyst caused by a congenital tooth.

Conclusions

A swollen mandibular gingival alveolar ridge was seen at birth, though no feeding problems or other complications were noted. For the present patient, in consideration of age and surgical stress, the first choice for therapy was regular follow-up examination.

背景出生体重不足 2500 克被定义为低出生体重，早产、怀孕 37 周内的活产和胎儿生长受限是最常见的原因。先天性（出生时）牙齿是指出生时已经萌出的牙齿，可能是原生牙齿，也可能是编外牙齿。病例报告一名低出生体重儿被怀疑患有先天性下颌中切牙萌出囊肿。在两个月的检查中，牙龈牙槽嵴肿胀已经消失，并发现两颗下颌前牙在同一部位萌出。诊断结果为先天性牙齿引起的萌出囊肿。结论患者出生时即出现下颌龈齿槽嵴肿胀，但未发现喂养问题或其他并发症。考虑到该患者的年龄和手术压力，治疗的首选方法是定期随访检查。

引用次数: 0

Progress of LPS-induced apical lesion in rat immature mandibular molars LPS诱导大鼠未成熟下颌磨牙根尖损伤的研究进展

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Pediatric Dental Journal

Pub Date : 2023-04-01 DOI: 10.1016/j.pdj.2022.12.001

Chikako Nakajima , Maiko Fujita-Otani , Yuko Mikuni-Takagaki , Kuniomi Nakamura , Kouki Hidaka , Akira Kawata , Ryota Kawamata , Shigenari Kimoto

Introduction

The objective was to assess the process of apical periodontitis induced by injecting Porphyromonas gingivalis lipopolysaccharide (Pg LPS) that is followed by regeneration of roots in premature permanent tooth. A novel operation table was introduced to facilitate endodontic treatment of mandibular molars.

Materials and Methods

Pulp of mandibular first molars of 6-week Wistar rats were exposed by drilling, inoculated with 0.6 μg Pg LPS and sealed with glass ionomer cement. After 1 and 2 weeks rats were sacrificed and the molar roots compared with those of vehicle controls by protein array analysis and (histo) morphology/chemistry. Micro-CT imaging visualized the lesion, and non-decalcified frozen serial sections were HE stained and subjected to TRACP-5b/ALP activity staining and immunohistochemical staining.

Results

Quantitative induction of inflammation enabled us to examine the effects of LPS-injection: micro-CT images exhibited much larger radiolucent apical lesions than did controls; CD68 (M1+ M2±) cell surface marker was more intense in Pg-1w and then subsided while CD163 (M1- M2+) was more intense in Pg-2w. Staining of IL-4, which induces M2 polarization, and angiogenic markers, VEGF/CD34 was intense in Pg-1w than in controls.

Conclusion

The introduced apparatus facilitated accurate mandible operation with ease. Thus, stages of pulpal infection were reproduced quantitatively with a small amount of Pg LPS. Proteins expressed in the root apex where inflammation occurred and the lesion in the surrounding alveolar bone revealed the inflammation time course in the immature permanent teeth. This mandibular model turned out quite useful for clinical and pharmaceutical developments in the future.

前言:目的是评估注射牙龈卟啉单胞菌脂多糖(Pg LPS)致过早恒牙牙根再生的过程。介绍了一种新型的手术台，方便了下颌磨牙的根管治疗。材料与方法采用钻孔法暴露6周龄Wistar大鼠下颌第一磨牙牙髓，接种0.6 μg LPS，玻璃离子水门栓封闭。1周和2周后处死大鼠，用蛋白质阵列分析和(组织)形态学/化学方法将其与对照进行比较。显微ct成像显示病变，非脱钙冷冻连续切片进行HE染色，并进行TRACP-5b/ALP活性染色和免疫组织化学染色。结果定量诱导炎症使我们能够检验lps注射的效果:微ct图像显示比对照组更大的放射性根尖病变;CD68 (M1+ M2±)细胞表面标记物在Pg-1w时较强后减弱，而CD163 (M1- M2+)细胞表面标记物在Pg-2w时较强。诱导M2极化的IL-4和血管生成标志物VEGF/CD34的染色在Pg-1w中较对照组强烈。结论所介绍的器械可方便、准确地完成下颌骨手术。因此，用少量Pg LPS定量再现了牙髓感染的分期。炎症发生的根尖和周围牙槽骨病变的蛋白表达揭示了未成熟恒牙炎症的时间过程。这个下颌模型对未来的临床和药物开发非常有用。

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引用次数: 0

Panoramic imaging may detect morphologically abnormal temporomandibular joints in children with juvenile idiopathic arthritis 全景成像可以发现儿童特发性关节炎的颞下颌关节形态异常

IF 0.8 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Pediatric Dental Journal

Pub Date : 2023-04-01 DOI: 10.1016/j.pdj.2023.01.004

Malin Collin , Nikolaos Christidis , Malin Ernberg , Laila Wiklander , Linda Z. Arvidsson , Tore A. Larheim , Britt Hedenberg-Magnusson

Objective

To investigate the reliability of panoramic imaging (PAN) with cone beam computed tomography (CBCT) as gold standard to distinguish between normal and abnormal temporomandibular joint (TMJ) morphology in a sample of children with juvenile idiopathic arthritis (JIA).

Material and method

In this prospective cohort study, 106 PAN and 108 CBCT examinations from 54 children were obtained. A classification system with reference images was developed and used to discriminate between normal and abnormal TMJ morphology. The severity of abnormality and additional findings were registered. Three experienced and calibrated maxillofacial radiologists evaluated the images and intra- and inter-reader agreement was calculated.

Results

Consensus diagnosis of abnormal TMJ morphology on PAN and on CBCT was registered in 27.6% and 28.1% of the joints, respectively. There were differences between the two imaging modalities regarding severity grading of abnormality and registration of additional findings. With CBCT abnormal TMJ morphology was frequently graded as more severe and additional findings such as erosions and osteophytes more frequently found.

Conclusion

With trained readers, PAN was found to distinguish between morphologically normal and abnormal TMJs equally often as CBCT. Thus, the method seems valuable for assessing TMJ involvement in children with JIA. However, CBCT was found to be superior for assessing severity of abnormality and additional diagnostic information.

目的探讨锥束计算机断层扫描(CBCT)全景成像(PAN)作为鉴别幼年特发性关节炎(JIA)患儿颞下颌关节(TMJ)形态正常与异常的金标准的可靠性。材料和方法在这项前瞻性队列研究中，获得了54名儿童的106份PAN和108份CBCT检查。建立了一种基于参考图像的分类系统，用于区分正常和异常TMJ形态学。记录异常的严重程度和其他发现。三位经验丰富且经过校准的颌面放射科医师评估图像，并计算阅读器内部和阅读器之间的一致性。结果在PAN和CBCT上一致诊断TMJ形态异常的比例分别为27.6%和28.1%。两种成像方式在异常的严重程度分级和附加发现的登记方面存在差异。在CBCT中，异常的TMJ形态通常被分级为更严重，并且更多地发现诸如侵蚀和骨赘等附加症状。结论在训练有素的阅读者中，PAN与CBCT同样能区分形态正常和异常的颞下颌关节。因此，该方法对于评估JIA患儿颞下颌关节受累似乎很有价值。然而，发现CBCT在评估异常严重程度和附加诊断信息方面更优越。

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引用次数: 0