Pub Date : 2023-09-27DOI: 10.9734/sajrm/2023/v16i4315
Lawrence O. Amadi, None Mark Happines C., None Nrior, R. R.
The aim of this research were to determine the antibiogram and effects of methanolic turmeric extract and alum on Escherichia coli in some borehole and sachet water in Rivers State respectively. The various concentrations (100mg/ml,50mg/ml,25mg/ml and 12.5mg/ml) of these combinations, methanolic turmeric extract, Alum, MTE+ Alum were tested respectively for antibacterial activity on some strains of E. coli isolated from borehole and sachet water samples. These were compared with an antibiotic standard, using chloramphenicol as a positive control. Antibacterial activity was assessed using disc diffusion method (DDM) respectively. Of these combinations, methanolic turmeric extracts in synergism with Alum (MTE+Alum) exhibited the lowest mean diameter of inhibitory zone (DIZ) values of 5.0-20.0mm and Alum exhibited the largest mean of inhibitory zone (DIZ) values of 8.0-20.0mm on the test organism using disc diffusion method (DDM) respectively. There was no inhibitory zone with MTE+Aum at 12.5 concentration whereas (DIZ) values for methanolic turmeric extract ranged from 8.0-16.0mm by DDM. The susceptibility of combinations were more pronounced against CP064383 E. coli (20.0mm), CP089272 E. coli (14.0mm), AF099077 E.coli (14.0mm) and LG142154 E.coli (18.0mm) respectively. This results revealed that chloramphenicol inhibited the largest DIZ values. However, the activity of chloramphenicol revealed that purified and tested antibiotic should be used as the drug of choice for treatments. And the synergistic effects of methanolic turmeric extract plus Alum was effective against all strains of E.coli with concentration of 100mg/ml and can be used as second line of treatment against infections caused by E.coli. E. coli isolates with a prevalence of 100% were obtained as the test organisms. Susceptibility pattern of the test isolates showed 100% susceptibility to Gentamycin,75% by chloramphenicol, Ciprofloxacin and Vancomycin. They were resistant to Cefotaxime (75%) and Cotriazole (25%) respectively. Multiple antibiotic resistance index for test isolates revealed 3(75%) of four E.coli strains was >0.2.The results for total heterotrophic bacterial count showed that there was no significant difference (p>0.05) in the mean counts sampling locations Ikwerre, Obio/Akpor and Phalga. Faecal Coliform Count revealed that there was no significant difference (p>0.05) in the mean counts with sachet water having the highest values of (2.77±0.14, 2.76±0.09 and 2.77±0.17) Log10CFU/ml while borehole water revealed least counts of (1.46±1.29, 0.79±1.18 and 1.86±1.44) Log10CFU/ml. In conclusion, this study demonstrated the potentials of Alum, MTE in synergism with alum as choice of treatment caused by E. coli in water samples from the study area.
{"title":"Effects of Methanolic Turmeric Extract, Alum on E. coli in Borehole & Sachet Water PH.","authors":"Lawrence O. Amadi, None Mark Happines C., None Nrior, R. R.","doi":"10.9734/sajrm/2023/v16i4315","DOIUrl":"https://doi.org/10.9734/sajrm/2023/v16i4315","url":null,"abstract":"The aim of this research were to determine the antibiogram and effects of methanolic turmeric extract and alum on Escherichia coli in some borehole and sachet water in Rivers State respectively. The various concentrations (100mg/ml,50mg/ml,25mg/ml and 12.5mg/ml) of these combinations, methanolic turmeric extract, Alum, MTE+ Alum were tested respectively for antibacterial activity on some strains of E. coli isolated from borehole and sachet water samples. These were compared with an antibiotic standard, using chloramphenicol as a positive control. Antibacterial activity was assessed using disc diffusion method (DDM) respectively. Of these combinations, methanolic turmeric extracts in synergism with Alum (MTE+Alum) exhibited the lowest mean diameter of inhibitory zone (DIZ) values of 5.0-20.0mm and Alum exhibited the largest mean of inhibitory zone (DIZ) values of 8.0-20.0mm on the test organism using disc diffusion method (DDM) respectively. There was no inhibitory zone with MTE+Aum at 12.5 concentration whereas (DIZ) values for methanolic turmeric extract ranged from 8.0-16.0mm by DDM. The susceptibility of combinations were more pronounced against CP064383 E. coli (20.0mm), CP089272 E. coli (14.0mm), AF099077 E.coli (14.0mm) and LG142154 E.coli (18.0mm) respectively. This results revealed that chloramphenicol inhibited the largest DIZ values. However, the activity of chloramphenicol revealed that purified and tested antibiotic should be used as the drug of choice for treatments. And the synergistic effects of methanolic turmeric extract plus Alum was effective against all strains of E.coli with concentration of 100mg/ml and can be used as second line of treatment against infections caused by E.coli. E. coli isolates with a prevalence of 100% were obtained as the test organisms. Susceptibility pattern of the test isolates showed 100% susceptibility to Gentamycin,75% by chloramphenicol, Ciprofloxacin and Vancomycin. They were resistant to Cefotaxime (75%) and Cotriazole (25%) respectively. Multiple antibiotic resistance index for test isolates revealed 3(75%) of four E.coli strains was >0.2.The results for total heterotrophic bacterial count showed that there was no significant difference (p>0.05) in the mean counts sampling locations Ikwerre, Obio/Akpor and Phalga. Faecal Coliform Count revealed that there was no significant difference (p>0.05) in the mean counts with sachet water having the highest values of (2.77±0.14, 2.76±0.09 and 2.77±0.17) Log10CFU/ml while borehole water revealed least counts of (1.46±1.29, 0.79±1.18 and 1.86±1.44) Log10CFU/ml. In conclusion, this study demonstrated the potentials of Alum, MTE in synergism with alum as choice of treatment caused by E. coli in water samples from the study area.","PeriodicalId":21776,"journal":{"name":"South Asian Journal of Research in Microbiology","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135579122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The study was conducted to isolate and identify Klebsiella pneumoniae from children affected by pneumonia in Dinajpur district. This research includes sample collection from pneumonia affected children, isolation and identification of Klebsiella pneumoniae from those samples, molecular detection and antibiotic sensitivity of the identified bacteria. In this research, the samples were collected from nasal secretion of children between 6 months to 10 years old. Then isolation, identification and molecular characterization of Klebsiella pneumoniae from those samples were done. The collection of samples and research work was carried out from May, 2020 to April, 2021. All research work was performed in the Bacteriology laboratory of Microbiology Department, HSTU, Dinajpur. To conduct the study, a total 60 samples were collected from 4 different hospitals in Dinajpur district. Then the samples were brought to the Bacteriology laboratory, Department of Microbiology, HSTU and divided into 5 age category. These samples were then processed and cultural tests were performed in various differential and selective media. Then selected samples were chosen for biochemical tests. After analysing biochemical test results, further selected samples were passed for molecular test to identify the presence of Klebsiella pneumoniae. At last antibiotic sensitivity tests were performed.
In this test, specific primer for Klebsiella pneumoniae was used to detect the presence of bacteria in the samples. After the cultural, biochemical and molecular tests, total 7 (11.66%) samples were positive among 60 isolates. Among those samples, 2 samples were positive between 6 months to 1 year age for the detection of Klebsiella pneumoniae which is around 14.28%, 2 samples were positive between 1 year to 3 years age which is around 15.38%, 1 sample was positive between 3 years to 5 years age which is around 10%, 1 sample was positive between 5 years to 7 years age which is around 8.33% and 1 sample was positive between 7 years to 10 years age which is around 9.09%. Then molecular detection was done by performing PCR test using specific primer for Klebsiella pneumoniae. At last antibiotic sensitivity test was performed which shows that Klebsiella pneumoniae is resistant to Amoxicillin, Ampicillin, Doxycycline, Erythromycin, Penicillin G and sensitive to Gentamicin, Streptomycin, Azithromycin, Levofloxacin, Tetracycline, Neomycin. All the results resemble recent studies as it is a normal inhabitant of human nosocomial pathway but it holds potential threats for children because in immunocompromised condition, infections can be occurred by Klebsiella pneumoniae which can lead to serious illness becoming more and more resistant to antibiotics.
{"title":"Isolation and Molecular Detection of Klebsiella pneumoniae from Children Affected by Pneumonia in Dinajpur District, Bangladesh","authors":"Md. Ashikur Rahman, Mst. Deloara Begum, Farzana Afroz, Md. Khalechur Rahman","doi":"10.9734/sajrm/2023/v16i4314","DOIUrl":"https://doi.org/10.9734/sajrm/2023/v16i4314","url":null,"abstract":"The study was conducted to isolate and identify Klebsiella pneumoniae from children affected by pneumonia in Dinajpur district. This research includes sample collection from pneumonia affected children, isolation and identification of Klebsiella pneumoniae from those samples, molecular detection and antibiotic sensitivity of the identified bacteria. In this research, the samples were collected from nasal secretion of children between 6 months to 10 years old. Then isolation, identification and molecular characterization of Klebsiella pneumoniae from those samples were done. The collection of samples and research work was carried out from May, 2020 to April, 2021. All research work was performed in the Bacteriology laboratory of Microbiology Department, HSTU, Dinajpur. To conduct the study, a total 60 samples were collected from 4 different hospitals in Dinajpur district. Then the samples were brought to the Bacteriology laboratory, Department of Microbiology, HSTU and divided into 5 age category. These samples were then processed and cultural tests were performed in various differential and selective media. Then selected samples were chosen for biochemical tests. After analysing biochemical test results, further selected samples were passed for molecular test to identify the presence of Klebsiella pneumoniae. At last antibiotic sensitivity tests were performed.
 In this test, specific primer for Klebsiella pneumoniae was used to detect the presence of bacteria in the samples. After the cultural, biochemical and molecular tests, total 7 (11.66%) samples were positive among 60 isolates. Among those samples, 2 samples were positive between 6 months to 1 year age for the detection of Klebsiella pneumoniae which is around 14.28%, 2 samples were positive between 1 year to 3 years age which is around 15.38%, 1 sample was positive between 3 years to 5 years age which is around 10%, 1 sample was positive between 5 years to 7 years age which is around 8.33% and 1 sample was positive between 7 years to 10 years age which is around 9.09%. Then molecular detection was done by performing PCR test using specific primer for Klebsiella pneumoniae. At last antibiotic sensitivity test was performed which shows that Klebsiella pneumoniae is resistant to Amoxicillin, Ampicillin, Doxycycline, Erythromycin, Penicillin G and sensitive to Gentamicin, Streptomycin, Azithromycin, Levofloxacin, Tetracycline, Neomycin. All the results resemble recent studies as it is a normal inhabitant of human nosocomial pathway but it holds potential threats for children because in immunocompromised condition, infections can be occurred by Klebsiella pneumoniae which can lead to serious illness becoming more and more resistant to antibiotics.","PeriodicalId":21776,"journal":{"name":"South Asian Journal of Research in Microbiology","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135536422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-25DOI: 10.9734/sajrm/2023/v16i4313
L. O. Amadi, T. Sampson, Nwala Noble Iwezor
MRSA is a major contributor to skin infections, bloodstream infections, toxic shock syndrome, and joint inflammation. Aspergillus flavus can result in a range of health issues these problems include allergic reactions, aspergilloma, both invasive and non-invasive. infections are a matter of importance for public health. Aspergillus flavus and Methicillin-resistant Staphylococcus aureus (MRSA) resistance to both antibiotics and antifungal medications put the public at risk.This study therefore was carried out to investigate the antimicrobial susceptibility pattern of Aspergillus flavus and Methicillin resistant Staphylococcus aureus (MRSA) isolated from publicly used toilets in Port Harcourt, Rivers State Nigeria. Eighty (80) samples were collected for a period of two months from five public toilets using the sedimentation air sampling method. Samples were subjected to isolation and identification, antibiotics and antifungal susceptibility test using Kirby-Bauer disk diffusion method, plant extracts and molecular identification of bacterial isolates for analysis. The susceptibility profile showed that MRSA were resistant to Ofloxacin (61%), Ceftazidime (92.30%), Levoflaxcin (92.30%), Vancomycin (77 %), Gentamycin (61%), Azithromycin (46.2%) and cefotaxime (46.2%) and susceptible to Imipenem (100%), Meropenem (92.32%). Ketoconazole and nystatin both antifungals were both effective on the A. flavus. Methanol extract of Ocimum grastissimum was more effective followed by Psidium guajava and moringa oleifera on MRSA but also less effective in A. flavus. The MAR index ranged from 0.1 to 0.8 which showed that 60% of MRSA isolates had MAR index of 0.8, while 20% had MAR index of 0.4 and 0.5. The antimicrobial activity of the extracts is promising as the extracts could be used as a cheap antimicrobial for the treatment of infections cause by these test organisms. Conclusively, this study revealed both organisms present in toilet air, their vulnerability patterns was established, their resistance gene verified, and explore the potential use of natural plant compounds on them, would assist in mitigating public health.
{"title":"Antimicrobial Resistance Profile of Airborne Aspergillus flavus and Methicillin-Resistant Staphylococcus aureus in Public Toilets within Port Harcourt, Nigeria","authors":"L. O. Amadi, T. Sampson, Nwala Noble Iwezor","doi":"10.9734/sajrm/2023/v16i4313","DOIUrl":"https://doi.org/10.9734/sajrm/2023/v16i4313","url":null,"abstract":"MRSA is a major contributor to skin infections, bloodstream infections, toxic shock syndrome, and joint inflammation. Aspergillus flavus can result in a range of health issues these problems include allergic reactions, aspergilloma, both invasive and non-invasive. infections are a matter of importance for public health. Aspergillus flavus and Methicillin-resistant Staphylococcus aureus (MRSA) resistance to both antibiotics and antifungal medications put the public at risk.This study therefore was carried out to investigate the antimicrobial susceptibility pattern of Aspergillus flavus and Methicillin resistant Staphylococcus aureus (MRSA) isolated from publicly used toilets in Port Harcourt, Rivers State Nigeria. Eighty (80) samples were collected for a period of two months from five public toilets using the sedimentation air sampling method. Samples were subjected to isolation and identification, antibiotics and antifungal susceptibility test using Kirby-Bauer disk diffusion method, plant extracts and molecular identification of bacterial isolates for analysis. The susceptibility profile showed that MRSA were resistant to Ofloxacin (61%), Ceftazidime (92.30%), Levoflaxcin (92.30%), Vancomycin (77 %), Gentamycin (61%), Azithromycin (46.2%) and cefotaxime (46.2%) and susceptible to Imipenem (100%), Meropenem (92.32%). Ketoconazole and nystatin both antifungals were both effective on the A. flavus. Methanol extract of Ocimum grastissimum was more effective followed by Psidium guajava and moringa oleifera on MRSA but also less effective in A. flavus. The MAR index ranged from 0.1 to 0.8 which showed that 60% of MRSA isolates had MAR index of 0.8, while 20% had MAR index of 0.4 and 0.5. The antimicrobial activity of the extracts is promising as the extracts could be used as a cheap antimicrobial for the treatment of infections cause by these test organisms. Conclusively, this study revealed both organisms present in toilet air, their vulnerability patterns was established, their resistance gene verified, and explore the potential use of natural plant compounds on them, would assist in mitigating public health.","PeriodicalId":21776,"journal":{"name":"South Asian Journal of Research in Microbiology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135864986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-25DOI: 10.9734/sajrm/2023/v16i3312
None Chibuike, P. M., None Wemedo, S. A., None Williams J. O., None Ugboma, C. J., D.N. Ogbonna
Pollutants such as crude oil spills in an environment, affect the physical, chemical and biological properties of that environment. This study was conducted to determine the effect of seasonal variations on the microbiological and physicochemical characteristics of three crude oil-polluted wetlands in Rivers State, Nigeria. Soil samples were collected at 3 depths (0-15cm, 15-30cm and 30-45cm) with the aid of a hand auger, sampling was done for a period of twelve months covering the rainy (March to August) and dry seasons (September to February). Samples were analyzed for physicochemical characteristics, using standard analytical and microbiological methods. The data obtained was analyzed using the statistical package for social science (SPSS) version 22 and Duncan’s multiple range test was used to separate means where differences occurred. Microbiological analyses showed that significantly higher microbial counts were observed in the dry season than in the rainy season in the wetland samples which could be due to favourable environmental conditions during the period of study. Wetland soil total heterotrophic bacterial (THB) count in the wet season ranged from 1.09x107cfu/g to 10.45x107cfu/g and from 2.43x107cfu/g to 18.56x107cfu/g in the dry season. Total heterotrophic bacteria had the highest population in all soil depths (0-15cm, 15-30cm and 30-45cm) in both seasons. Hydrocarbon-utilizing bacteria such as Bacillus subtilllis, B. rigui, B. flexus, Lysinibacillus macrolides, Staphylococcus aureus, Proteus penneri and fungi such as Aspergillus species, Fusarium species, Mucor species and Rhizopus species were genetically identified in this study. Temperature and other physicochemical parameters in the wetlands were altered due to the variation in season. Higher temperature ranges were observed in the dry season than in the rainy season as seen in Iwofe, temperature ranged from 26.500C (0-15cm) to 28.500C (30-45cm) in the rainy season while in the dry season it ranged from 31.500C (0-15cm) to 33.500C (30-45cm) which was above FEPA permissible limit of 300C for soil temperature. The study showed that season of study as well as crude oil spillage have significant effects on the microbiology and physicochemical characteristics of wetlands and therefore, contribute to microbiological degradation in wetlands.
{"title":"Seasonal Influence on the Microbiology and Physicochemistry of Crude Oil Polluted Wetlands","authors":"None Chibuike, P. M., None Wemedo, S. A., None Williams J. O., None Ugboma, C. J., D.N. Ogbonna","doi":"10.9734/sajrm/2023/v16i3312","DOIUrl":"https://doi.org/10.9734/sajrm/2023/v16i3312","url":null,"abstract":"Pollutants such as crude oil spills in an environment, affect the physical, chemical and biological properties of that environment. This study was conducted to determine the effect of seasonal variations on the microbiological and physicochemical characteristics of three crude oil-polluted wetlands in Rivers State, Nigeria. Soil samples were collected at 3 depths (0-15cm, 15-30cm and 30-45cm) with the aid of a hand auger, sampling was done for a period of twelve months covering the rainy (March to August) and dry seasons (September to February). Samples were analyzed for physicochemical characteristics, using standard analytical and microbiological methods. The data obtained was analyzed using the statistical package for social science (SPSS) version 22 and Duncan’s multiple range test was used to separate means where differences occurred. Microbiological analyses showed that significantly higher microbial counts were observed in the dry season than in the rainy season in the wetland samples which could be due to favourable environmental conditions during the period of study. Wetland soil total heterotrophic bacterial (THB) count in the wet season ranged from 1.09x107cfu/g to 10.45x107cfu/g and from 2.43x107cfu/g to 18.56x107cfu/g in the dry season. Total heterotrophic bacteria had the highest population in all soil depths (0-15cm, 15-30cm and 30-45cm) in both seasons. Hydrocarbon-utilizing bacteria such as Bacillus subtilllis, B. rigui, B. flexus, Lysinibacillus macrolides, Staphylococcus aureus, Proteus penneri and fungi such as Aspergillus species, Fusarium species, Mucor species and Rhizopus species were genetically identified in this study. Temperature and other physicochemical parameters in the wetlands were altered due to the variation in season. Higher temperature ranges were observed in the dry season than in the rainy season as seen in Iwofe, temperature ranged from 26.500C (0-15cm) to 28.500C (30-45cm) in the rainy season while in the dry season it ranged from 31.500C (0-15cm) to 33.500C (30-45cm) which was above FEPA permissible limit of 300C for soil temperature. The study showed that season of study as well as crude oil spillage have significant effects on the microbiology and physicochemical characteristics of wetlands and therefore, contribute to microbiological degradation in wetlands.","PeriodicalId":21776,"journal":{"name":"South Asian Journal of Research in Microbiology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135864634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.9734/sajrm/2023/v16i3308
None Osho I. B., None Oyekanmi B. A., None Osanyintuyi S. G.
Aims: Oyster mushroom is rich in secondary metabolites of pharmacological importance. This study evaluates the effect of ethanolic extract of Oyster mushroom on the vital organs of Staphylococcus aureus infected Wistar rats after seven days of administration.
Study Design: Completely randomized design was used in the study.
Place and Duration of Study: This study was carried out at the Microbiology, Parasitology and Ethnoveterinary medicine Unit of the Department of Animal Production and Health, Federal University of Technology, Akure, Nigeria, between March and December 2022.
Methodology: The mushroom was processed using a cold extraction technique. A bacterial suspension of Staphylococcus aureus was inoculated via oral route into the experimental animals, which were randomly distributed into six groups of five. Group 1: normal control; group 2: positive control; group 3: negative control, inoculated but received no antimicrobial; and group 4 to 6 were inoculated, and administered with 625, 1250 and 2500 mg dose of the extract respectively. The treatment was administered for seven days, after which blood samples were cultured for the bacterial count and vital organs were analysed for pathological changes.
Results: The colony count was significantly raised at 625 mg dose while the dose ranging from 1250 to 2500 mg yielded insignificant bacterial growth (P<0.01). The percentage weight gain was significantly lower (P<0.01) in 1250 mg extract in comparison with the negative control after 7 days complete treatment but there was no statistical variation in the 7 days post-treatment percentage weight gain and the relative organ weight (P<0.01).The histological sections showed no variation from normal controls except 625 mg liver that showed some vacuolations within the hepatocytes.
Conclusion: The organ-body mean weight was proportionate, and the histological sections of the liver, kidney, skin, lungs, heart and spleen were indicative of no anatomical variations as compared with the normal control tissues. The beneficial effect of P. ostreatus on the vital organs was further established by the active clearing of S. aureus infection at 1250 to 2500 mg dose with no observable pathological change in the tissues. The bioactive agents inherent in P. ostreatus were effective against S. aureus infection. The vacuolations observed in the low dose liver sections unveiled the ill effect of under-dose treatment and its consequence on the liver cells. The histopathological investigations were suggestive of the safety and tolerance of P. ostreatus to the body system. Nevertheless, further studies should be carried out on its toxicological profiles.
{"title":"Effects of Oyster Mushroom (Pleurotus ostreatus) on Body Weight and Pathology of Vital Organs in Pathogenic Staph Infection","authors":"None Osho I. B., None Oyekanmi B. A., None Osanyintuyi S. G.","doi":"10.9734/sajrm/2023/v16i3308","DOIUrl":"https://doi.org/10.9734/sajrm/2023/v16i3308","url":null,"abstract":"Aims: Oyster mushroom is rich in secondary metabolites of pharmacological importance. This study evaluates the effect of ethanolic extract of Oyster mushroom on the vital organs of Staphylococcus aureus infected Wistar rats after seven days of administration.
 Study Design: Completely randomized design was used in the study.
 Place and Duration of Study: This study was carried out at the Microbiology, Parasitology and Ethnoveterinary medicine Unit of the Department of Animal Production and Health, Federal University of Technology, Akure, Nigeria, between March and December 2022.
 Methodology: The mushroom was processed using a cold extraction technique. A bacterial suspension of Staphylococcus aureus was inoculated via oral route into the experimental animals, which were randomly distributed into six groups of five. Group 1: normal control; group 2: positive control; group 3: negative control, inoculated but received no antimicrobial; and group 4 to 6 were inoculated, and administered with 625, 1250 and 2500 mg dose of the extract respectively. The treatment was administered for seven days, after which blood samples were cultured for the bacterial count and vital organs were analysed for pathological changes.
 Results: The colony count was significantly raised at 625 mg dose while the dose ranging from 1250 to 2500 mg yielded insignificant bacterial growth (P<0.01). The percentage weight gain was significantly lower (P<0.01) in 1250 mg extract in comparison with the negative control after 7 days complete treatment but there was no statistical variation in the 7 days post-treatment percentage weight gain and the relative organ weight (P<0.01).The histological sections showed no variation from normal controls except 625 mg liver that showed some vacuolations within the hepatocytes.
 Conclusion: The organ-body mean weight was proportionate, and the histological sections of the liver, kidney, skin, lungs, heart and spleen were indicative of no anatomical variations as compared with the normal control tissues. The beneficial effect of P. ostreatus on the vital organs was further established by the active clearing of S. aureus infection at 1250 to 2500 mg dose with no observable pathological change in the tissues. The bioactive agents inherent in P. ostreatus were effective against S. aureus infection. The vacuolations observed in the low dose liver sections unveiled the ill effect of under-dose treatment and its consequence on the liver cells. The histopathological investigations were suggestive of the safety and tolerance of P. ostreatus to the body system. Nevertheless, further studies should be carried out on its toxicological profiles.","PeriodicalId":21776,"journal":{"name":"South Asian Journal of Research in Microbiology","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136153414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.9734/sajrm/2023/v16i3310
Morakinyo Abraham Adebambo, Mitsan Olley, Ismaila Ibrahim, Ajongbolo Abigail Olayinka, Azeez Oyemomi Ibrahim, Samuel Idowu Omotosho, Ayodele Kamal Alabi, Bawonda Ene Omenyi, Kehinde Oluwafunmilayo Sito
Aim: This work was conducted between the period of April 2022 and March 2023 to investigate the prevalence and predisposing factors of enteric parasites among children accessing medical healthcare at the Federal Medical Center keffi, Nasarawa State.
Study Design: The study was a cross-sectional study.
Methodology: Fresh stool specimens were collected into sterile bottles from children aged 1-15 (246 males and 194 females) who accessed medical healthcare at the Federal Medical Center keffi, Nasarawa State between the period of April 2022 and March 2023. Information such as age, gender, and drinking water sources were obtained from the subjects through a structured questionnaire. The stool specimens were observed visually for colour, consistency, and presence of blood, pus, and adult worms while the concentration of the eggs, cysts, and larvae of the intestinal parasites was carried out using the formol ether method and viewed with X10 and X40 magnifications of the binocular microscope. Data obtained from this study were analyzed using the chi-square test by the use of Statistical Package for Social Sciences (SPSS) version (21.0). Values obtained were considered significant at 95% probability.
Results: An overall prevalence of 27.26% was obtained in the study participants with a total of five species of intestinal parasites identified. The parasites include; Entamoeba coli, Entamoeba histolytica, Giardia lamblia, Strongyloides stercoralis, and Trichomonas hominis. Entamoeba. histolytica was the most prevalent (15.45%) while S. stercoralis was the least prevalent (1.36%). In this study, males recorded a higher prevalence of Entamoeba. histolytica (16.49%) than females (14.63%) likewise for E. coli (5.14%) and (4.07%), Strongyloides stercoralis (1.55%) and (1.22%) respectively. In contrast, females recorded a higher prevalence of Giardia lamblia (2.85%) than males (2.58%) and Trichomonas hominis (3.25%) and (1.03%) respectively. The prevalence of intestinal parasites varied significantly among the age groups, with the age group 1-5 years being the most susceptible to E. histolytica (45.71%). Children who drank river water had the highest prevalence of parasitic infection (57.14%) while those who drank borehole water had the lowest majority (14.29%).
Conclusion: The high prevalence of intestinal parasites observed in this study in relation to the sources of drinking water of the subjects suggests a major predisposing factor to intestinal parasitic infections. Therefore, the provision of potable drinking water and public enlightenment on proper hygiene practices in the study area is of great importance.
{"title":"Prevalence of Intestinal Parasites among Children Accessing Medical Healthcare at the Federal Medical Centre Keffi, Nasarawa State, Nigeria","authors":"Morakinyo Abraham Adebambo, Mitsan Olley, Ismaila Ibrahim, Ajongbolo Abigail Olayinka, Azeez Oyemomi Ibrahim, Samuel Idowu Omotosho, Ayodele Kamal Alabi, Bawonda Ene Omenyi, Kehinde Oluwafunmilayo Sito","doi":"10.9734/sajrm/2023/v16i3310","DOIUrl":"https://doi.org/10.9734/sajrm/2023/v16i3310","url":null,"abstract":"Aim: This work was conducted between the period of April 2022 and March 2023 to investigate the prevalence and predisposing factors of enteric parasites among children accessing medical healthcare at the Federal Medical Center keffi, Nasarawa State.
 Study Design: The study was a cross-sectional study. 
 Methodology: Fresh stool specimens were collected into sterile bottles from children aged 1-15 (246 males and 194 females) who accessed medical healthcare at the Federal Medical Center keffi, Nasarawa State between the period of April 2022 and March 2023. Information such as age, gender, and drinking water sources were obtained from the subjects through a structured questionnaire. The stool specimens were observed visually for colour, consistency, and presence of blood, pus, and adult worms while the concentration of the eggs, cysts, and larvae of the intestinal parasites was carried out using the formol ether method and viewed with X10 and X40 magnifications of the binocular microscope. Data obtained from this study were analyzed using the chi-square test by the use of Statistical Package for Social Sciences (SPSS) version (21.0). Values obtained were considered significant at 95% probability.
 Results: An overall prevalence of 27.26% was obtained in the study participants with a total of five species of intestinal parasites identified. The parasites include; Entamoeba coli, Entamoeba histolytica, Giardia lamblia, Strongyloides stercoralis, and Trichomonas hominis. Entamoeba. histolytica was the most prevalent (15.45%) while S. stercoralis was the least prevalent (1.36%). In this study, males recorded a higher prevalence of Entamoeba. histolytica (16.49%) than females (14.63%) likewise for E. coli (5.14%) and (4.07%), Strongyloides stercoralis (1.55%) and (1.22%) respectively. In contrast, females recorded a higher prevalence of Giardia lamblia (2.85%) than males (2.58%) and Trichomonas hominis (3.25%) and (1.03%) respectively. The prevalence of intestinal parasites varied significantly among the age groups, with the age group 1-5 years being the most susceptible to E. histolytica (45.71%). Children who drank river water had the highest prevalence of parasitic infection (57.14%) while those who drank borehole water had the lowest majority (14.29%).
 Conclusion: The high prevalence of intestinal parasites observed in this study in relation to the sources of drinking water of the subjects suggests a major predisposing factor to intestinal parasitic infections. Therefore, the provision of potable drinking water and public enlightenment on proper hygiene practices in the study area is of great importance.","PeriodicalId":21776,"journal":{"name":"South Asian Journal of Research in Microbiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136236106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-21DOI: 10.9734/sajrm/2023/v16i3309
None George, P. A., None Akani, N. P., None Ugboma, C. J.
This study investigated the effect of Zingiber officinale (Ginger) and Allum sativum (Garlic) on biofilm forming Staphylococcus aureus isolated from selected boreholes in Port Harcourt city Local Government Area of Rivers State. Twenty four water samples were collected from 4 randomly selected borehole. Borikiri had the highest number of isolates that produced biofilm, while Elelennwo had the lowest number. Out of 23 isolates of Staphylococcus aureus, 14 were positive for biofilm production. Hemolysis production range of these isolates was from alpha, beta and gamma. Filter paper disc were inoculated with various plant extract concentrations. Methanol garlic extract at 100mg/ml had the highest range of zone of inhibition at Borikiri when compared to methanol ginger extract while methanol garlic extract at 100mg/ml had no range at Elelenwo when compared to methanol ginger extract. This study suggests that methanolic ginger and garlic extracts can be used as a potential anti-biofilm agent in borehole water, to reduce the risk of bacterial biofilm formation.
Surveillance systems should be increased for assessing risk factors of diseases and to provide strategies to prevent and protect public health.
{"title":"Effects of Methanolic Ginger and Garlic Extracts on Biofilm Forming Staphylococcus aureus Isolated from Borehole Water","authors":"None George, P. A., None Akani, N. P., None Ugboma, C. J.","doi":"10.9734/sajrm/2023/v16i3309","DOIUrl":"https://doi.org/10.9734/sajrm/2023/v16i3309","url":null,"abstract":"This study investigated the effect of Zingiber officinale (Ginger) and Allum sativum (Garlic) on biofilm forming Staphylococcus aureus isolated from selected boreholes in Port Harcourt city Local Government Area of Rivers State. Twenty four water samples were collected from 4 randomly selected borehole. Borikiri had the highest number of isolates that produced biofilm, while Elelennwo had the lowest number. Out of 23 isolates of Staphylococcus aureus, 14 were positive for biofilm production. Hemolysis production range of these isolates was from alpha, beta and gamma. Filter paper disc were inoculated with various plant extract concentrations. Methanol garlic extract at 100mg/ml had the highest range of zone of inhibition at Borikiri when compared to methanol ginger extract while methanol garlic extract at 100mg/ml had no range at Elelenwo when compared to methanol ginger extract. This study suggests that methanolic ginger and garlic extracts can be used as a potential anti-biofilm agent in borehole water, to reduce the risk of bacterial biofilm formation.
 Surveillance systems should be increased for assessing risk factors of diseases and to provide strategies to prevent and protect public health.","PeriodicalId":21776,"journal":{"name":"South Asian Journal of Research in Microbiology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136153241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-14DOI: 10.9734/sajrm/2023/v16i3307
J. O. Williams, R. R. Nrior, E. C. Gold
Aquatic nitrogen-fixing bacteria play a crucial role in maintaining the nitrogen cycle and supporting primary productivity in freshwater and brackish water ecosystems. The activities of oil and gas industries operating within the coastal region of PortHarcourt releases effluents that contain various chemicals including corrosion inhibitors into the aquatic environment which can significantly affect the aquatic organisms including the nitrogen-fixing bacteria. Hence, this study was aimed to determine the comparative eco-toxicological effect of corrosion inhibitors on aquatic nitrogen fixing bacterium (Nitrosomonas sp.) in Fresh and Brackish water ecosystem. Fresh water and brackish water samples were collected from Chokocho stream in Etche Local Government Area and Eagle Island Port Harcourt, all in Rivers State, Nigeria. Standard toxicity procedure was applied on rectangular cut-out crude oil pipeline metal (ME) coated with corrosion inhibitors: Ambercil (AMB) and X-PRO 99 inhibitor (XPRO) immersed in freshwater (FW) prepared at concentrations of 25%, 50%, 75% and 100% for Nitrosomons sp. These inhibitors were tested with Nitrosomonas sp. at 0, 4, 8, 12 and 24hrs separately for each toxicant. The median lethal concentration (LC50) was employed to compare the toxicities of the different toxicants on the test organisms. The result for percentage survival of Nitrosomonas sp decreased when exposed to various concentrations listed above for 24. The LC50 (%) result (noting, that the lower the LC50, the more toxic the toxicant): of Nitrosomonas sp decreased in the following order: FW + ME (85.5) > BW + ME (86.7) > Both FW + AMB & FW + XPRO (86.8) > BW + XPRO (87.9) > BW + ME + XPRO (89.1) > BW + AMB (89.7) > FW + ME + XPRO (94.9). The above results revealed that Nitrosomonas sp decreased in percentage survival with an increase in concentration. The result showed that the effluents of metals coated with corrosion inhibitors (ME + AMB & ME + XPRO) were more toxic to Nitrosomonas sp in brackish water than freshwater while the effluents of XPRO & AMB not coated on metals were more toxic in freshwater than in brackish water. In conclusion, corrosion inhibitors when coated on metals, AMB corrosion inhibitor was more toxic than XPRO corrosion inhibitors in brackish and freshwater. Based on the findings, the use of XPRO corrosion inhibitor should be a best option for coating crude oil pipeline due to its relative low toxicity in upstream sector of the Nigeria petroleum industry.
水生固氮细菌在维持淡水和咸淡水生态系统氮循环和支持初级生产力方面起着至关重要的作用。在porttharcourt沿海地区作业的石油和天然气工业的活动将含有各种化学物质(包括腐蚀抑制剂)的废水排放到水生环境中，这可以严重影响包括固氮细菌在内的水生生物。因此，本研究旨在比较不同缓蚀剂对淡水和咸淡水生态系统中水生固氮细菌(Nitrosomonas sp.)的生态毒理学影响。从尼日利亚河流州埃切地方政府地区的乔科乔河和鹰岛哈科特港采集了淡水和微咸水样本。对矩形切割原油管道金属(ME)采用标准毒性程序，涂有缓蚀剂:Ambercil (AMB)和X-PRO 99缓蚀剂(XPRO)，浸入浓度分别为25%、50%、75%和100%的淡水(FW)中，用于亚硝化somons sp.。这些抑制剂分别在0、4、8、12和24小时分别与亚硝化somons sp.进行毒性测试。采用中位致死浓度(LC50)比较不同毒物对试验生物的毒性。结果表明，亚硝化单胞菌在不同浓度条件下的存活率均有所下降。亚硝化somonas sp的LC50(%)结果(注意LC50越低，毒性越强)依次递减:FW + ME (85.5) >BW + ME (86.7) >FW + AMB &FW + XPRO (86.8) >BW + XPRO (87.9) >BW + ME + XPRO (89.1) >BW + AMB (89.7) >Fw + me + xpro(94.9)。结果表明，亚硝化单胞菌的存活率随浓度的增加而降低。结果表明，金属表面涂覆缓蚀剂(ME + AMB &ME + XPRO)对咸淡水中亚硝化单胞菌的毒性大于淡水;未涂覆金属的AMB在淡水中的毒性大于在微咸水中的毒性。综上所述，在微咸水和淡水环境中，AMB缓蚀剂在金属表面涂覆时的毒性大于XPRO缓蚀剂。根据研究结果，由于XPRO缓蚀剂的毒性相对较低，因此在尼日利亚石油工业的上游部门，使用XPRO缓蚀剂应该是原油管道涂层的最佳选择。
{"title":"Comparative Eco-toxicological Effect of Corrosion Inhibitors on Aquatic Nitrogen Fixing Bacterium in Fresh and Brackish Water Ecosystem","authors":"J. O. Williams, R. R. Nrior, E. C. Gold","doi":"10.9734/sajrm/2023/v16i3307","DOIUrl":"https://doi.org/10.9734/sajrm/2023/v16i3307","url":null,"abstract":"Aquatic nitrogen-fixing bacteria play a crucial role in maintaining the nitrogen cycle and supporting primary productivity in freshwater and brackish water ecosystems. The activities of oil and gas industries operating within the coastal region of PortHarcourt releases effluents that contain various chemicals including corrosion inhibitors into the aquatic environment which can significantly affect the aquatic organisms including the nitrogen-fixing bacteria. Hence, this study was aimed to determine the comparative eco-toxicological effect of corrosion inhibitors on aquatic nitrogen fixing bacterium (Nitrosomonas sp.) in Fresh and Brackish water ecosystem. Fresh water and brackish water samples were collected from Chokocho stream in Etche Local Government Area and Eagle Island Port Harcourt, all in Rivers State, Nigeria. Standard toxicity procedure was applied on rectangular cut-out crude oil pipeline metal (ME) coated with corrosion inhibitors: Ambercil (AMB) and X-PRO 99 inhibitor (XPRO) immersed in freshwater (FW) prepared at concentrations of 25%, 50%, 75% and 100% for Nitrosomons sp. These inhibitors were tested with Nitrosomonas sp. at 0, 4, 8, 12 and 24hrs separately for each toxicant. The median lethal concentration (LC50) was employed to compare the toxicities of the different toxicants on the test organisms. The result for percentage survival of Nitrosomonas sp decreased when exposed to various concentrations listed above for 24. The LC50 (%) result (noting, that the lower the LC50, the more toxic the toxicant): of Nitrosomonas sp decreased in the following order: FW + ME (85.5) > BW + ME (86.7) > Both FW + AMB & FW + XPRO (86.8) > BW + XPRO (87.9) > BW + ME + XPRO (89.1) > BW + AMB (89.7) > FW + ME + XPRO (94.9). The above results revealed that Nitrosomonas sp decreased in percentage survival with an increase in concentration. The result showed that the effluents of metals coated with corrosion inhibitors (ME + AMB & ME + XPRO) were more toxic to Nitrosomonas sp in brackish water than freshwater while the effluents of XPRO & AMB not coated on metals were more toxic in freshwater than in brackish water. In conclusion, corrosion inhibitors when coated on metals, AMB corrosion inhibitor was more toxic than XPRO corrosion inhibitors in brackish and freshwater. Based on the findings, the use of XPRO corrosion inhibitor should be a best option for coating crude oil pipeline due to its relative low toxicity in upstream sector of the Nigeria petroleum industry.","PeriodicalId":21776,"journal":{"name":"South Asian Journal of Research in Microbiology","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134913488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-12DOI: 10.9734/sajrm/2023/v16i2306
Odiase, Edgar Onyeka, Olley Mitsan, Daniel Ohilebo Ugbomoiko, Theophilus Ogie Erameh, Ezekiel Dauda Gambo, Ofili Sandra Kanwulia, Muhammad Adamu Ibrahim, Paul Yiran Ntasin
Aim: The study aimed to ascertain the prevalence of tuberculosis among HIV-positive patients at the Federal Medical Center Asaba in Delta State, Nigeria.
Study Design: This study engaged a cross-sectional study design to prevalence of Mycobacterium Tuberculosis among HIV Patients Attending Federal Medical Centre Asaba, Delta State.
Place and Duration of the Study: The study was conducted in Federal Medical Center. Data collection spanned a specific duration from November, 2022 to January, 2023.
Methodology: A total of 188 samples were obtained from known HIV patients. The patients were selected by random sampling technique. The samples were analysed using GeneXpert machine (GX2.1 model) with the nuclei acid amplification (NAA) of DNA mycobacterium tuberculosis complex (MTBC) and resistance to rifampicin. Demographic data of participants were obtained through questionnaires.
Results: Out of 188 samples from HIV patients analyzed, MTB was detected in 13 (8.7%) patients with the highest prevalence recorded among male subjects 6(12%). Age group 19-29 was the most prevalent of MTB among the test subjects.
Conclusion: Mycobacterium tuberculosis is widespread among HIV patients in Asaba, Delta state, according to these data. As a result, patients must be encouraged to adhere to treatment and preventive measures.
{"title":"Prevalence of Mycobacterium tuberculosis among HIV Patients Attending Federal Medical Centre Asaba, Delta State, Nigeria","authors":"Odiase, Edgar Onyeka, Olley Mitsan, Daniel Ohilebo Ugbomoiko, Theophilus Ogie Erameh, Ezekiel Dauda Gambo, Ofili Sandra Kanwulia, Muhammad Adamu Ibrahim, Paul Yiran Ntasin","doi":"10.9734/sajrm/2023/v16i2306","DOIUrl":"https://doi.org/10.9734/sajrm/2023/v16i2306","url":null,"abstract":"Aim: The study aimed to ascertain the prevalence of tuberculosis among HIV-positive patients at the Federal Medical Center Asaba in Delta State, Nigeria.
 Study Design: This study engaged a cross-sectional study design to prevalence of Mycobacterium Tuberculosis among HIV Patients Attending Federal Medical Centre Asaba, Delta State.
 Place and Duration of the Study: The study was conducted in Federal Medical Center. Data collection spanned a specific duration from November, 2022 to January, 2023.
 Methodology: A total of 188 samples were obtained from known HIV patients. The patients were selected by random sampling technique. The samples were analysed using GeneXpert machine (GX2.1 model) with the nuclei acid amplification (NAA) of DNA mycobacterium tuberculosis complex (MTBC) and resistance to rifampicin. Demographic data of participants were obtained through questionnaires.
 Results: Out of 188 samples from HIV patients analyzed, MTB was detected in 13 (8.7%) patients with the highest prevalence recorded among male subjects 6(12%). Age group 19-29 was the most prevalent of MTB among the test subjects.
 Conclusion: Mycobacterium tuberculosis is widespread among HIV patients in Asaba, Delta state, according to these data. As a result, patients must be encouraged to adhere to treatment and preventive measures.","PeriodicalId":21776,"journal":{"name":"South Asian Journal of Research in Microbiology","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135826712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-30DOI: 10.9734/sajrm/2023/v16i2305
L. Gomes, J. Prado
Medicinal plants are the basis for the development of numerous drugs, ensuring their effectiveness through pharmaceutical properties, from antimicrobial action to the treatment of infectious diseases. Thus, the present study aimed to carry out a survey of the species cultivated in the municipal garden of Sobral - CE, Brazil, in order to verify in the literature, the medicinal potential and their biological properties. For this, the survey was carried out between January and February 2022, while the bibliographic review followed through the PubMed, SciElo and LILACS platforms. The survey identified 70 species, divided into gardening, fruit, medicinal, native and arboreal groups. Of these, about 90.9% had some therapeutic properties, whether antimicrobial, antiparasitic, antioxidant, anti-inflammatory or antinociceptive. Some of these even exhibited all these properties, as is the case of Moringa oleifera, becoming a model for studies. Thus, the raised species have potential for the development of new therapeutic alternatives, whether in the development of a new drug from extracts and essential oils, or even through the enhancement of existing drugs.
{"title":"Survey of Species Cultivated in Brazil and their Biological Applications: A Review","authors":"L. Gomes, J. Prado","doi":"10.9734/sajrm/2023/v16i2305","DOIUrl":"https://doi.org/10.9734/sajrm/2023/v16i2305","url":null,"abstract":"Medicinal plants are the basis for the development of numerous drugs, ensuring their effectiveness through pharmaceutical properties, from antimicrobial action to the treatment of infectious diseases. Thus, the present study aimed to carry out a survey of the species cultivated in the municipal garden of Sobral - CE, Brazil, in order to verify in the literature, the medicinal potential and their biological properties. For this, the survey was carried out between January and February 2022, while the bibliographic review followed through the PubMed, SciElo and LILACS platforms. The survey identified 70 species, divided into gardening, fruit, medicinal, native and arboreal groups. Of these, about 90.9% had some therapeutic properties, whether antimicrobial, antiparasitic, antioxidant, anti-inflammatory or antinociceptive. Some of these even exhibited all these properties, as is the case of Moringa oleifera, becoming a model for studies. Thus, the raised species have potential for the development of new therapeutic alternatives, whether in the development of a new drug from extracts and essential oils, or even through the enhancement of existing drugs.","PeriodicalId":21776,"journal":{"name":"South Asian Journal of Research in Microbiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79918130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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