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At glance to the plants having anti-inflammatory activity: A review 抗炎植物研究进展综述
Pub Date : 2022-06-25 DOI: 10.31254/phyto.2022.11311
Jankhana Baraiya, B. Chauhan, Zuli Shingala
From time immemorial man is dependent on plants. The human body has a natural affinity to plants and their products, which are easily absorbed as well as healthier. Medicinal plants are used in treatment of almost all disease. Plants are vast source of active biological compound for new drugs which are safer as well as cost effective. Inflammation is biological response of the human immune system that can be triggered by a variety of factors like damaged cells, toxic compounds, and pathogens. Conventional drugs used for treatment of inflammation has so many disadvantages thus people looking forward safer and effective drug. Various plants are traditionally used in treatment of inflammatory conditions. This review includes some traditionally used herbal plants as an anti-inflammatory drug.
自古以来,人类就以植物为食。人体对植物及其产物有天然的亲和力,容易吸收,也更健康。药用植物几乎可用于治疗所有疾病。植物是开发新药的活性生物化合物的重要来源,具有较高的安全性和成本效益。炎症是人体免疫系统的生物反应,可由多种因素引发,如受损的细胞、有毒化合物和病原体。用于治疗炎症的常规药物有很多缺点,人们期待更安全有效的药物。各种植物传统上用于治疗炎症。本文综述了一些传统上用作消炎药的草本植物。
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引用次数: 0
Phytochemical screening and effects of aqueous extract of Acalypha wilkesiana Müll. Arg on isolated toad heart 木耳多糖水提物的植物化学筛选及其作用。一个孤立的蟾蜍心脏
Pub Date : 2022-06-25 DOI: 10.31254/phyto.2022.11305
Wensleslace Landry Mve Mendame, Boris Achille Eyi Mintsa, Alban-Michel Nguema Nguema, A. B. Pambo-Pambo, Ibrahim
Medicinal plants are real sources of bioactive molecules. The objective of the present study was to assess the effects of aqueous extract of Acalypha wilkesiana (ALWILEXT) on toad heart. Phytochemical screening of the aqueous extract revealed the presence of bioactives, namely: coumarins, flavones, polyphenols, alkaloids, tannins, terpenes and saponosides. The results obtained show that ALWILEXT, at concentrations ranging from 5.10-5 to 5.10-5g / ml, causes negative inotropic and chronotropic effects on the isolated toad heart, similar to those of acetylcholine although less marked. These effects suggest the presence of adrenomimetics in the aqueous extract. The aqueous extract of Acalypha wilkesiana is said to contain concomitantly adrenomimetics which would justify its use in the treatment of hypertension.
药用植物是生物活性分子的真正来源。本研究的目的是评估白果水提物对蟾蜍心脏的影响。水提物的植物化学筛选显示存在生物活性,即:香豆素、黄酮、多酚、生物碱、单宁、萜烯和皂苷。结果表明,ALWILEXT在5.10-5 ~ 5.10-5g / ml浓度范围内对离体蟾蜍心脏产生负性肌力和变时作用,类似于乙酰胆碱,但不那么明显。这些影响表明在水萃取物中存在拟肾上腺素。据说白果的水提取物含有伴随的肾上腺素,这将证明它在高血压治疗中的使用是合理的。
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引用次数: 0
Coccinia indica: A Comprehensive Review of Pharmacology, Therapeutic Applications, Nutritional Potentials, and Future Prospects 印度球菌:药理学、治疗应用、营养潜力和未来展望的综合综述
Pub Date : 2022-06-25 DOI: 10.31254/phyto.2022.11313
R. Padma, V. G.
The pharmacognosy, phytochemistry, nutritional value, and ethnopharmacological activity of Coccinia indica (C. indica) are discussed in this review. Many patented compositions generated from C. indica are now widely available around the world. This has resulted in a rise in research on the phytochemical elements of C. indica as well as ethnopharmacological activities. This belongs to the Cucurbitaceae family. Indigenous peoples used several portions of the plant for food and medicine. When the fruit of C. indica is green in colour, it is used as a vegetable, and when it ripens into a beautiful scarlet hue, it is eaten fresh. C. indica's young leaves and branch tips are frequently utilised in traditional medical systems in Asia, including Ayurvedic, Siddha, and Unani. Traditionally, different parts of this plant used in folk medicine for many purposes, such as anti-diabetic, antimicrobial, anti-inflammatory, antioxidant, antimalarial, antidyslipidemic, anticancer, analgesic, antipyretic, antitussive, antinociceptive, hepatoprotective, ant obesity, and neuroprotective function. Many traditional medicines are made from medicinal plants, minerals, and organic materials, which is why this review is focused on that particular plant. The utilisation of numerous medicinal plants from the traditional medicine system for the treatment of various ailments has sparked increasing interest in recent years. Traditional medicine has employed C. indica as a home treatment for a variety of diseases.
本文综述了印度球菌的生药学、植物化学、营养价值和民族药理学活性。许多由籼稻产生的专利成分现在在世界各地广泛使用。这导致了对籼稻植物化学成分和民族药理学活性研究的增加。这是葫芦科植物。土著居民用这种植物的几个部分作为食物和药物。当印度紫果呈绿色时,它被用作蔬菜,当它成熟成美丽的猩红色时,它被新鲜食用。印度的嫩叶和枝尖经常在亚洲的传统医疗系统中使用,包括阿育吠陀,悉达和乌纳尼。传统上,这种植物的不同部分用于民间医学的许多用途,如抗糖尿病、抗菌、抗炎、抗氧化、抗疟疾、抗血脂异常、抗癌、镇痛、解热、止咳、抗炎、保肝、抗肥胖和神经保护功能。许多传统药物都是由药用植物、矿物质和有机材料制成的,这就是为什么本综述的重点是这种特定的植物。近年来,利用传统医学系统中的许多药用植物治疗各种疾病引起了越来越多的兴趣。传统医学已将印度锥虫作为多种疾病的家庭治疗方法。
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引用次数: 0
Experimental evaluation on analgesic activity of Erandamoola (Ricinus communis) collected in three different seasons wsr to Dravya Samgrahana Kaala 不同季节采收蓖麻镇痛作用的实验评价
Pub Date : 2022-06-25 DOI: 10.31254/phyto.2022.11306
Bingi Ashok, M. Suma, B. Sudhakara, CV Lacitha
About: Dravya samgrahana kaala is an important scientific documentation mentioned in Ayurveda where there will be change in activity and phytochemical profile of plants in different seasons. Erandamoola (Ricinus communis) is an important medicinal plant where roots are particularly indicated as analgesic. As per Dravya samgrahana vidhi roots are to be collected in Hemanth-Shishira or Greeshma rutu or Pravarat rutu. Hence with this background study has been planned to evaluate analgesic activity of the Erandamoola (Ricinus cumunis) collected in Greeshma (EMG) and Pravrutritu (EMP) and Shishiraritu (EMS) using Eddy’s Hot plate method, in swiss albino mice. Materials and Methods: Roots of matured plant will be collected in three different seasons, shade dried, powdered and used for the study. Swiss Albino mice were randomly grouped into 3 groups of six animals each. Group I served as control, Group II serve as standard with administration of Tramadol whereas Group III (EMG), Group IV (EMP) and Group V (EMS) serve as the test group with administration of 200 mg/kg body weight (Erandmoola collected in Greeshma (EMG), Pravrut ritu (EMP) and Shishira ritu (EMS) respectively. Results: Erandamoola collected in greeshma and pravrut ritus show almost similar pain threshold with a slight increase in values than drug collected in greeshma ritu. Conclusion: Thus Erandamoola (Ricinus communis) can be efficiently used as an analgesic, simulatneously season or Samgrahana kaala is having a definite role on drug activity.
关于:Dravya samgrahana kaala是阿育吠陀中提到的重要科学文献,其中植物在不同季节的活性和植物化学特征会发生变化。蓖麻(Ricinus communis)是一种重要的药用植物,其根尤其具有镇痛作用。根据梵文samgrahana, vidhi的根被收集在Hemanth-Shishira或Greeshma rutu或Pravarat rutu中。因此,在此背景下,我们计划用Eddy’s Hot plate法评价在Greeshma (EMG)和Pravrutritu (EMP)和Shishiraritu (EMS)中收集的Erandamoola (Ricinus cumunis)对瑞士白化小鼠的镇痛活性。材料和方法:在三个不同的季节收集成熟植物的根,遮荫干燥,粉末状,用于研究。将瑞士白化病小鼠随机分为3组,每组6只。第一组为对照组,第二组为标准组,给予曲马多;第三组(肌电图)、第四组(EMP)和第五组(EMS)为试验组,分别给药200 mg/kg体重(采自Greeshma (EMG)、Pravrut ritu (EMP)和Shishira ritu (EMS))。结果:青斑病组和pravrut ritus组的Erandamoola痛阈值与青斑病组的痛阈值基本相同,但略高于青斑病组。结论:蓖麻是一种有效的镇痛药,同时加味或加味对药物活性有一定的作用。
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引用次数: 1
Pharmaceutical evidence of Piper guineense on reproductive toxicityt 豚鼠派珀生殖毒性的药学证据
Pub Date : 2022-06-25 DOI: 10.31254/phyto.2022.11315
O. M. Onwuka, N. Nwosu, Adaobi Linda Okerulu
Objectives: Nutritional value and health benefits of Piper guineense (a spice known as Uziza in Igbo language of Nigeria) cannot be overemphasized. Its therapeutic inputs on reproductive toxicity were elucidated. Study approach: Literature survey was carried out in various electronic search databases such as Google scholar, Crossref and pubmed. The survey done February 2022 – March 2022 considered literatures that reported the impact of Piper guineense on reproductive system as well as reproductive toxicity. The search keys include; “Piper guineense and reproductive health” “Piper guineense and reproductive toxicity” “Piper guineense on non-heavy metals induced reproductive toxicity” “Piper guineense on heavy metals induced reproductive toxicity” “Piper guineense on lead, cadmium, and arsenic induced reproductive toxicity”. The search keywords were used respectively and collectively. Findings: Eight (8) reports were found most appropriate for the pharmaceutical evidence of Piper guineense on reproduction; which suggests its essential therapeutic input on reproductive toxicity. Conclusively, Piper guineense is a potential vital ingredient for pharmaceuticals, used to ameliorate reproductive toxicity.
目的:几内亚胡椒(一种在尼日利亚伊博语中被称为Uziza的香料)的营养价值和健康益处怎么强调都不为过。并对其生殖毒性的治疗投入进行了阐述。研究方法:在Google scholar、Crossref、pubmed等各种电子检索数据库中进行文献调查。这项于2022年2月至2022年3月进行的调查考虑了报道几内亚派珀对生殖系统的影响以及生殖毒性的文献。搜索关键字包括;《豚鼠Piper与生殖健康》、《豚鼠Piper与生殖毒性》、《豚鼠Piper对非重金属诱导的生殖毒性》、《豚鼠Piper对重金属诱导的生殖毒性》、《豚鼠Piper对铅、镉和砷诱导的生殖毒性》。搜索关键词分别使用和组合使用。结果:8篇报道最适合豚鼠繁殖的药学证据;这表明它对生殖毒性有重要的治疗作用。最后,几内亚胡椒是一种潜在的重要药物成分,用于改善生殖毒性。
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引用次数: 1
Phytopharmacological characterization of different extracts and fractions of Cyclea peltata 环草不同提取物及组分的植物药理学研究
Pub Date : 2022-06-25 DOI: 10.31254/phyto.2022.11304
R. Poonghuzhali, S. Samraj, A. Nisha, S. N. Nair, M. Priya
Cyclea peltata is a shrub belongs to Menispermiaceae family and is commonly known as “Pedal” or “Pada thalli”. The plant has been used since ancient times in traditional medicine as a healing herb for the treatment of various ailments such as skin infections, wounds, antipyretic, diuretic, diabetes, asthma, jaundice and snakebite poisoning. The objective of the present study was to characterize the active phytochemical constituents present in the aqueous, methanolic and n-hexane, dichloromethane, nbutanol, water fractions of methanolic extracts of C. peltata. To analyse the potent bioactive compounds, present in the extracts and fractions, Fourier Transform Infrared Spectroscopy was used. The qualitative phytochemical screening unveiled the presence of steroids, alkaloids, glycosides, flavonoids, terpenoids, saponins in aqueous extract and alkaloids, phenols, tannins, flavonoids, terpenoids, saponins in methanolic extract. The fractions of C. peltata showed the presence of alkaloids, phenols, tannins, flavonoids, terpenoids, saponins. The Infrared Spectroscopy profiling showed the presence of alcohols, phenols, amines, carboxylic acids, aldehydes, ketones, alkenes, alkanes and aromatic compounds. From the study, it is concluded that the bioactive compounds present in the extracts and fractions of C. peltata was alkaloids, phenols, flavonoids and terpenoids which is responsible for the diverse pharmacological properties.
青环草(cycloa peltata)是一种灌木,属于半边草科,俗称“足跖草”或“青环草”。自古以来,这种植物在传统医学中就被用作治疗各种疾病的草药,如皮肤感染、伤口、解热、利尿剂、糖尿病、哮喘、黄疸和蛇咬中毒。本研究的目的是表征水、甲醇和正己烷、二氯甲烷、丁醇、甲醇提取物的水馏分中存在的活性植物化学成分。为了分析有效的生物活性化合物,存在于提取物和馏分,傅里叶变换红外光谱被使用。定性植物化学筛选发现,水提物中存在甾体、生物碱、苷类、黄酮类、萜类、皂苷,甲醇提物中存在生物碱、酚类、单宁类、黄酮类、萜类、皂苷。该部位主要含有生物碱、酚类、单宁、黄酮类、萜类、皂苷等化学成分。红外光谱分析表明,化合物中存在醇类、酚类、胺类、羧酸类、醛类、酮类、烯烃、烷烃和芳香族化合物。研究结果表明,黄酮、萜类、生物碱、酚类是黄酮提取物和馏分中具有多种药理作用的活性成分。
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引用次数: 0
Hibiscus syriacus L.: A Critical Review of Medicinal Utility & Phytopharmacology with Mechanistic Approach 木槿:药用价值与植物药理学的评述与机制研究
Pub Date : 2022-06-25 DOI: 10.31254/phyto.2022.11312
A. Balkrishna, S. Mishra, A. Singh, Deepika Srivastava, Shalini Singh, V. Arya
Herbal medicine is an ancient form of medicine that has been used by humans for thousands of years. The vital systems of primordial medicines include Ayurveda, Siddha, Unani, and folk medicine and, the most developed and widely practiced medicinal system in India is Ayurveda. Hibiscus species are commonly shrubs, herbs or trees with many useful properties, of which H. syriacus is one of the prime species of the genus. It is endowed as the national flower of South Korea, commonly known as ‘Rose of Sharon’ and is found along valleys, open slopes, roadsides and sea cliffs. The plant species is used as a medicine in many diseases such as amoebic colitis, hemorrhoids, hemorrhoidal bleeding, migraine, headache, cold, cough, nausea, vomiting, abdominal pain, ascariasis, colitis, diarrhea, dysentery, dyspepsia, gas, stomach ache, hematochezia, ascariasis etc. Several biological activities of the plant are attributed to the presence of various active compounds like botulin, coumarins, fumaric acid, hydroquinone, is vitexin, linoleic acid, nonanoic acid, naringenin acid, Para hydroxybenzaldehyde, palmitic acid, Syracusans A-C, triterpenoids and vanillic acid. Some phytochemicals, including linolenic acid, palmitic acid, hydroxyhibiscone A, hibiscuses D, Syracusans A, pentacyclic triterpene esters, triterpenoid, nonanoic acid, anthocyanins, and others, are responsible for its biological importance like anti-cancer, anti-aging, anti-depressant, anti-fungal, anti-melanogenic, anti-oxidant, cytoprotective, neuroprotective, etc., Detailed information extracted by reviewing the medicinal utilities & Phytopharmacological properties, provide elaborated evidences for the application of H. syriacus in many ailments.
草药是一种古老的药物形式,已经被人类使用了数千年。原始药物的重要系统包括阿育吠陀,悉达,乌纳尼和民间医学,印度最发达和最广泛实践的医疗系统是阿育吠陀。木槿属植物通常是灌木、草本或乔木,具有许多有用的特性,其中叙利亚木槿是该属的主要物种之一。它被赋予韩国的国花,通常被称为“沙龙玫瑰”,在山谷、开阔的山坡、路边和海边悬崖上都能找到。该植物被用作许多疾病的药物,如阿米巴结肠炎、痔疮、痔疮出血、偏头痛、头痛、感冒、咳嗽、恶心、呕吐、腹痛、蛔虫病、结肠炎、腹泻、痢疾、消化不良、胀气、胃痛、便血、蛔虫病等。该植物的几种生物活性归因于各种活性化合物的存在,如肉毒杆菌素、香豆素、富马酸、对苯二酚、牡荆素、亚油酸、壬酸、柚皮素酸、对羟基苯甲醛、棕榈酸、雪山A-C、三萜和香草酸。一些植物化学物质,包括亚麻酸、棕榈酸、羟基木槿A、木槿D、雪城花A、五环三萜酯、三萜、壬酸、花青素等,具有抗癌、抗衰老、抗抑郁、抗真菌、抗黑素、抗氧化、细胞保护、神经保护等生物学意义,通过综述药用用途和植物药理性质提取了详细信息。为叙利亚红在许多疾病中的应用提供了详细的证据。
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引用次数: 0
Knowledge and attitude towards COVID-19 among university students 大学生对新冠肺炎的知识和态度
Pub Date : 2022-06-25 DOI: 10.31254/phyto.2022.11308
A. Zahoor, R. Malik, Ifqa Mushtaq Siddique
The present study aimed to assess the knowledge and attitude of university students about the new evolving coronavirus COVID-19. In this connection, the study was carried out among the students of SKUAST-K. A descriptive survey method was used to conduct the study. Under the jurisdiction of SKUAST-K, Shalimar, Srinagar, Faculty of Fisheries was selected by purposive sampling technique. The target population of the study comprised of the students of Faculty of Fisheries, Rangil, Ganderbal with total population size of 193. The sample of study constituted 100 students. Stratified random sampling technique was used for present study and the samples were taken proportionally with the total number of undergraduate and postgraduate students, with 62 students from U.G, 25 students from masters and 13 students from Ph.D. respectively. A self-administered questionnaire was developed to obtain information from the respondents. The data collected from the survey was analyzed using standard statistical tools like descriptive statistics such as frequency and percentage and inferential statistics such as Chi-square test. PAST 4.0 and SPSS version 20.0 was used for analysis of data. From the present study, it was concluded that majority of the respondents were having good knowledge towards COVID-19 and were very much aware about general information, cause, symptoms, transmission routes and prevention of the coronavirus disease. However, the respondents in the study were also having certain misconceptions pertaining to certain aspects of COVID-19. Majority of the respondents were of the opinion that imposing restrictions on travel to and from COVID-19 contaminated areas, closure of all educational institutes, limiting access to religious sites, isolating COVID-19 patients in special isolation wards, maintaining social distancing and locking down and quarantining whole population was a good decision by government. The respondents also showed a positive attitude towards role of media in covering COVID-19 pandemic. Furthermore, from the study, majority of the respondents disagreed that the government took all the necessary steps to tackle COVID19 virus successfully.
本研究旨在了解大学生对新型冠状病毒COVID-19的知识和态度。在这方面,研究是在SKUAST-K的学生中进行的。采用描述性调查方法进行研究。在斯利那加沙利马尔渔业学院的管辖下,通过有目的抽样技术选择了SKUAST-K。这项研究的目标人口包括甘德尔巴尔兰吉尔渔业学院的学生,总人口为193人。研究样本为100名学生。本研究采用分层随机抽样方法,样本按本科生和研究生总数的比例抽取,其中本科生62人,硕士生25人,博士生13人。制定了一份自我管理的调查问卷,以获取受访者的信息。使用频率、百分比等描述性统计和卡方检验等推理统计等标准统计工具对调查收集的数据进行分析。采用PAST 4.0和SPSS 20.0进行数据分析。从本研究中得出的结论是,大多数受访者对COVID-19有很好的了解,并且非常了解冠状病毒病的一般信息、病因、症状、传播途径和预防措施。然而,研究中的受访者对COVID-19的某些方面也存在某些误解。大多数受访者认为,限制进出疫情疫区、关闭所有教育机构、限制进入宗教场所、将COVID-19患者隔离在特殊隔离病房、保持社会距离、封锁和隔离全体人口是政府的明智决定。受访者对媒体在新冠肺炎疫情报道中的作用也持积极态度。此外,从调查结果来看,大多数受访者不同意政府为成功应对新冠病毒采取了一切必要措施。
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引用次数: 0
Quassia amara L.: A Comprehensive Review of its Ethnomedicinal Uses, Phytochemistry, Pharmacology and Toxicity 番槐:民族药用、植物化学、药理及毒性研究综述
Pub Date : 2022-06-25 DOI: 10.31254/phyto.2022.11310
A. Balkrishna, Shalini Singh, Deepika Srivastava, Shalini Mishra, S. Rajput, V. Arya
Quassia amara Linn., is a shrub and world widely known as ‘bitter-wood’ belongs to Simaroubaceae family. The plant grows in sandy soils of lowland & highland forests, wet forests along riverbanks and, is native to Central Mexico to Southern tropical America and Guadalupe. A Surinamese man named Quassia which gained attention for treating fevers with a secret remedy based on this herb in 18th century, which Rolande took to Sweden in 1756 and disseminated its medicinal reputation across Europe. This species consists of various constituents namely β-carbonite, indole alkaloids & primarily, the bitter compounds known as quassinoids. Various studies indicate that Q. amara possess different biological properties namely anti-diabetic, anti-inflammatory, anti-hyperglycemic, anti-leishmanial, antimalarial, anti-nociceptive, anti-ulcer, anti-fertility and sedative. Fresh bark, leaves or wood extracts are used to treat digestive problems, malaria and hepatic disorders. In-depth literature analysis revealed that the plant is least explored and possess immense medicinal values. These studies pass the new ways to explore biological potential of this plant.
卡西娅·阿玛拉·林恩。它是一种灌木,被世界广泛称为“苦木”,属于苦木科。该植物生长在低地和高地森林的沙土中,河岸的潮湿森林,原产于墨西哥中部到热带美洲南部和瓜达卢佩。一位名叫夸西亚的苏里南人在18世纪用一种基于这种草药的秘密疗法治疗发烧,引起了人们的注意,罗兰德在1756年把它带到瑞典,并在欧洲传播了它的医学声誉。该物种由各种成分组成,即β-碳酸盐,吲哚生物碱和主要是苦味化合物,称为拟西番莲。各种研究表明,苦参具有抗糖尿病、抗炎、抗高血糖、抗利什曼原虫、抗疟疾、抗伤害、抗溃疡、抗生育和镇静等生物学特性。新鲜的树皮、树叶或木材提取物被用来治疗消化问题、疟疾和肝脏疾病。深入的文献分析表明,该植物被开发的最少,具有巨大的药用价值。这些研究为发掘该植物的生物学潜力开辟了新的途径。
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引用次数: 2
Analyzing phytochemicals activity of Colocasia esculenta and Prunus persica against Proteus mirabilis 土芋和桃李对变形杆菌的植物化学活性分析
Pub Date : 2022-06-05 DOI: 10.31254/phyto.2022.11302
Kailash Chandra Semwal, Shivani Gairola, Gautam Singh Bhandari, Sushil Giri, Mayank Kumar Rana, Amit Kumar, Tejpal
Serious infection of UTI is predominantly cause by Proteus mirabilis which is gram negative and motile bacteria with this if it contains antimicrobial resistance gene than it become a big problem which cannot be tackle with primary antibiotics mainly Beta-lactam antibiotics. Currently global health sector also faces antibiotic crisis. Two plants Colocasia esculenta and Prunus persica utilized for analysis of antimicrobial activity which can used to make therapy that could use against Proteus. Different-different extract of phytochemicals such as ethanol, methanol and chloroform show activity in different concentration against Proteus mirabilis.
尿路感染的严重感染主要是由奇异变形杆菌引起的,它是一种革兰氏阴性的运动菌,如果它含有抗微生物药物耐药基因,那么它就成为以β -内酰胺类抗生素为主的一级抗生素无法解决的大问题。目前,全球卫生部门也面临抗生素危机。利用土芋和桃李两种植物对变形杆菌的抑菌活性进行了分析,为研制抗变形杆菌的药物提供依据。乙醇、甲醇、氯仿等植物化学物质的不同提取物对变形杆菌具有不同浓度的活性。
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引用次数: 0
期刊
The Journal of Phytopharmacology
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