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2013 IEEE SENSORS最新文献

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Factors affecting blind localization of a glass micropipette using a high-density microelectrode array 利用高密度微电极阵列对玻璃微移液进行盲定位的影响因素
Pub Date : 2013-12-19 DOI: 10.1109/ICSENS.2013.6688361
M. Obien, A. Hierlemann, U. Frey
High-density microelectrode arrays (HDMEAs) provide the capability to measure extracellular electric potential from brain slices and dissociated cell cultures at high spatiotemporal resolution, which is attractive for neuroscience. Since the HDMEA enables to record the activity of single neurons at sub-cellular resolution, a combination with intracellular recording techniques, such as patch clamp, will allow for new in vitro experiments. Such combination technique requires precise localization of both the cell of interest and the glass micropipette (GM) with respect to the HDMEA. Here, we present a methodology to locate the three-dimensional (3D) position of a GM on the HDMEA without the use of an optical microscope. For the (x, y) position, the achieved accuracy is (±2μm, ±5μm), which is less than the electrode pitch of 18μm. For the z-position, the obtained accuracy is ±2μm for distances of 5-50μm between the GM tip and the HDMEA surface. We also observed that variations in size of GM tips and HDMEA electrodes have minimal effects on the blind localization performance. This approach shows the feasibility of automated navigation of a GM atop the HDMEA to patch a single cell in vitro.
高密度微电极阵列(HDMEAs)提供了在高时空分辨率下测量脑切片和游离细胞培养物的细胞外电位的能力,这对神经科学具有吸引力。由于HDMEA能够以亚细胞分辨率记录单个神经元的活动,因此与细胞内记录技术(如膜片钳)相结合,将允许进行新的体外实验。这种组合技术需要精确定位感兴趣的细胞和玻璃微移液管(GM)相对于HDMEA。在这里,我们提出了一种方法来定位三维(3D)的位置上的一个GM在HDMEA没有使用光学显微镜。对于(x, y)位置,获得的精度为(±2μm,±5μm),小于电极间距18μm。对于z-位置,在GM尖端与HDMEA表面之间的距离为5-50μm时,得到的精度为±2μm。我们还观察到,GM尖端和HDMEA电极的尺寸变化对盲定位性能的影响很小。这种方法显示了在HDMEA上自动导航GM贴片单细胞的可行性。
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引用次数: 3
Effects of imperfections on solid-wave gyroscope dynamics 缺陷对固波陀螺仪动力学的影响
Pub Date : 2013-12-19 DOI: 10.1109/ICSENS.2013.6688462
E. Yilmaz, D. Bindel
Solid-wave gyroscopes are symmetric resonators that sense rotation by measuring how Coriolis forces perturb a degenerate mode pair. The idealized dynamics of these devices are described by ODE models of two identical oscillators coupled by a perturbation due to rotation. In miniaturized solid-wave gyroscopes, geometric distortions due to imperfect fabrication also perturb the dynamics, and this limits sensing accuracy. In this work, we describe how geometric imperfections affect the dynamics of solid-wave gyroscopes. We also use selection rules both to find qualitative information about what types of geometry perturbations most affect sensor performance and to accelerate computations.
固体波陀螺仪是对称谐振器,通过测量科里奥利力对简并模对的扰动来感知旋转。这些器件的理想动力学是由由旋转引起的扰动耦合的两个相同振子的ODE模型来描述的。在小型化的固体波陀螺仪中,由于制造不完善造成的几何畸变也会干扰动力学,这限制了传感精度。在这项工作中,我们描述了几何缺陷如何影响固波陀螺仪的动力学。我们还使用选择规则来找到关于哪种类型的几何扰动最影响传感器性能的定性信息,并加速计算。
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引用次数: 7
Sensitivity-enhanced ultrasonic microsensors on buckled diaphragms through stress balance control of multilayered structure 基于多层结构应力平衡控制的屈曲膜片灵敏度增强超声微传感器
Pub Date : 2013-12-19 DOI: 10.1109/ICSENS.2013.6688389
K. Yamashita, Hikaru Tanaka, Yi Yang, M. Noda
Sensitivity of piezoelectric ultrasonic microsensors has been improved through a novel buckling control technique of the diaphragms of which upward buckling yields higher sensitivity than downward one. The diaphragms have compressive-and tensile-stressed layers, and a fabrication process has been developed to optimize the stress balance to generate an upward buckling moment. The fabricated sensors have yielded upward-buckled diaphragms in 92% of 196 ones on a wafer and an improved sensitivity to 6.7 times on average.
通过一种膜片向上屈曲比向下屈曲灵敏度更高的新型屈曲控制技术,提高了压电超声微传感器的灵敏度。膜片具有压缩和拉伸应力层,并且开发了一种制造工艺来优化应力平衡,以产生向上的屈曲力矩。在晶圆上196个传感器中,92%的传感器产生了向上弯曲的膜片,并且将灵敏度提高到平均6.7倍。
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引用次数: 8
Multiple sensor arrays for single cell metabolic analysis 用于单细胞代谢分析的多传感器阵列
Pub Date : 2013-12-19 DOI: 10.1109/ICSENS.2013.6688453
Ganquan Song, Rishabh M. Shetty, Haixin Zhu, Shashanka Ashili, Liqiang Zhang, Grace Kim, Andrew Shabilla, Wacey Teller, Q. Mei, L. Kelbauskas, Yanqing Tian, Hong Wang, Roger H. Johnson, D. Meldrum
We present the design, fabrication and characterization of multiple micro-pocket lid arrays used in live single cell metabolic analysis. In previous work we reported a platform for quantifying single cell oxygen consumption rates realized using a fused silica deep wet etching process. Here we extend that work to a dual-depth wet etching process for microfabrication of multiple sensor trapping (MST) lid arrays. Each lid comprises multiple micro-pockets. Oxygen, pH, other extra-cellular sensors, and reference dye were deposited in the pockets. In order to achieve simultaneous monitoring of multiple metabolic parameters, the lid array serves to hermetically seal arrays of microwells, each containing a single cell. The dual-depth etching process we developed can be easily applied to other glass-based microfabrication purposes requiring dual- or multiple-depth microstructures.
我们介绍了用于活单细胞代谢分析的多个微口袋盖阵列的设计,制造和表征。在以前的工作中,我们报道了一个量化单细胞耗氧率的平台,该平台使用熔融二氧化硅深湿蚀刻工艺实现。在这里,我们将这项工作扩展到双深度湿蚀刻工艺,用于多传感器捕获(MST)盖子阵列的微制造。每个盖子由多个微口袋组成。氧、pH值、其他细胞外传感器和参考染料沉积在口袋中。为了同时监测多种代谢参数,盖子阵列用于密封微孔阵列,每个微孔包含一个细胞。我们开发的双深度蚀刻工艺可以很容易地应用于其他需要双或多深度微结构的玻璃基微加工目的。
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引用次数: 0
The contactless active optical sensor for vehicle driver fatigue detection 用于车辆驾驶员疲劳检测的非接触式有源光学传感器
Pub Date : 2013-12-19 DOI: 10.1109/ICSENS.2013.6688139
K. Murawski, T. Sondej, K. Rózanowski, O. Truszczyński, M. Macander, L. Macander
In this paper we present the contactless active optical sensor for driver fatigue detection in variable weather and lighting conditions. The fatigue was determined by monitoring activity of the eyes. In our case the bright pupil effect was used. The brightness of the pupil was increased by developing a new keying technique of controlling the IR emitter signal. This technique caused the brightness to increase in comparison to the continuous signal by 50%on average. The new developed sensor, as well as, the image processing algorithm was used during the construction of the driver fatigue monitoring system. The system detects fatigue by analyzing the variability of the following signals: PERCLOSE, PEROPEN, blink frequency, activity of the eyes and pupil diameter.
本文提出了一种用于可变天气和光照条件下驾驶员疲劳检测的非接触式有源光学传感器。通过监测眼睛的活动来确定疲劳程度。在我们的例子中使用了亮瞳效果。通过开发一种新的控制红外发射信号的键控技术,提高了瞳孔亮度。该技术使亮度比连续信号平均提高50%。在构建驾驶员疲劳监测系统的过程中,采用了新研制的传感器和图像处理算法。该系统通过分析以下信号的变化来检测疲劳:PERCLOSE、PEROPEN、眨眼频率、眼睛活动和瞳孔直径。
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引用次数: 4
Room temperature ionic-liquid electrochemical gas sensor array system for real-time mine safety monitoring 用于矿井安全实时监测的室温离子-液体电化学气体传感器阵列系统
Pub Date : 2013-12-19 DOI: 10.1109/ICSENS.2013.6688143
Haitao Li, Xiaoyi Mu, Zhe Wang, Min Guo, Xiangqun Zeng, A. Mason
This paper presents a real-time, electrochemical gas sensor array system featuring room temperature ionic-liquid interfaces and targeting safety monitoring in underground mines. A prototype system was constructed using a custom ionic-liquid sensor array, a custom multi-mode electrochemical sensor readout board, and a commercial low power microcontroller board. Gas sensors for multiple mine gases were implemented in a 2 by 2 miniaturized array. A novel resource-sharing circuit tailored to our gas sensor array was utilized to significantly decrease power, cost and size while implementing two electrochemical detection modes. The system achieves a resolution as high as 0.01% vol in amperometry mode and 0.06% vol in impedance spectroscopy mode for oxygen as an example target gas.
本文提出了一种具有室温离子-液体界面和目标安全监测功能的实时电化学气体传感器阵列系统。采用定制的离子-液体传感器阵列、定制的多模电化学传感器读出板和商用低功耗微控制器板构建了原型系统。用于多种矿井气体的气体传感器采用2 × 2的小型化阵列。为我们的气体传感器阵列定制了一种新颖的资源共享电路,在实现两种电化学检测模式的同时,显著降低了功耗、成本和尺寸。对于以氧气为例的目标气体,该系统在安培模式下的分辨率高达0.01%,在阻抗谱模式下的分辨率高达0.06%。
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引用次数: 8
Electrical characterization of 26 × 26 ground reaction sensor array interfaced with two parallel electronic detection channels 具有两个平行电子探测通道的26 × 26地反应传感器阵列的电学特性
Pub Date : 2013-12-19 DOI: 10.1109/ICSENS.2013.6688251
Q. Guo, R. Surapaneni, Yu-Pin Hsu, C. Mastrangelo, D. Young
This paper presents the electrical characterization results of a 26 × 26 high-density ground reaction sensor array (HD-GRSA) interfaced with two parallel electronic detection channels. The system was developed for improving inertial measurement unit (IMU) positioning accuracy. The HD-GRSA is composed of 26 × 26 sensing nodes, which can measure dynamic ground force and shear strain associated with a ground locomotion gait. Each electronic detection channel consists of a front-end multiplexer that can sequentially connect individual sensing nodes from a 13 × 13 sub-array to a capacitance-to-voltage (C/V) converter followed by a 12-bit algorithmic ADC. The electronics were fabricated in a 0.35 μm CMOS process occupying an area of 7.7 mm2 for each channel while dissipating a DC power of 3 mW from a 3V supply. The HD-GRSA demonstrates the designed functionality achieving a gait ground velocity resolution of approximately 95 μmRMS/sec, limited by the electronic interference signals due to the long metal traces on the sensor array. Further performance improvement is expected by employing interference suppression techniques and better matching for critical wiring traces.
本文介绍了具有两个平行电子探测通道的26 × 26高密度地反应传感器阵列(HD-GRSA)的电学特性。该系统是为提高惯性测量单元(IMU)的定位精度而开发的。HD-GRSA由26 × 26个传感节点组成,可以测量与地面运动步态相关的动态地面力和剪切应变。每个电子检测通道由一个前端多路复用器组成,该多路复用器可以依次将来自13 × 13子阵列的各个传感节点连接到电容-电压(C/V)转换器,然后是一个12位算法ADC。电子器件采用0.35 μm CMOS工艺制造,每个通道占地7.7 mm2,从3V电源消耗3 mW的直流功率。HD-GRSA演示了设计的功能,实现了约95 μmRMS/sec的步态地面速度分辨率,受传感器阵列上长金属迹线引起的电子干扰信号的限制。通过采用干扰抑制技术和对关键布线进行更好的匹配,有望进一步提高性能。
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引用次数: 3
Ultra-high scanning speed chemical image sensor based on light addressable potentiometric sensor with analog micro-mirror 基于模拟微镜光可寻址电位传感器的超高扫描速度化学图像传感器
Pub Date : 2013-12-19 DOI: 10.1109/ICSENS.2013.6688484
Anirban Das, Tsung-Cheng Chen, Yi-Ting Lin, Chao‐Sung Lai, Y. Liao, Chia‐Ming Yang
In chemical image sensor, spatial resolution and scanning speed are the most important factors which may need to optimize and trade off. Before the minimization of spatial resolution, scanning speed of system needs to be improved to have an image in a short time within few seconds. In this study, ultra-high scanning speed of light addressable potentiometric sensor (LAPS) could be achieved by means of the combination of laser diode and single analog micro-mirror in light source. In the constant bias operation, an U-shape of pH solution can be detected within 8.5 sec for 14×121 points in the area of 3.2 mm×6.12 mm by using 5 kHz of ac signal in laser diode. The image resolution of the present LAPS system with 10 μm-thick Si3N4/3 nm-thick SiO2 on 500 μm-thick silicon wafer is 0.0116 mm2 which could be further improved by LAPS structure optimization with thinner substrate. A chemical image sensor with ultra-high scanning speed is demonstrated by the application of analog micro-mirror for LAPS.
在化学图像传感器中,空间分辨率和扫描速度是最重要的因素,可能需要优化和权衡。在空间分辨率最小化之前,需要提高系统的扫描速度,使其能够在短时间内在几秒内获得图像。在本研究中,光寻址电位传感器(LAPS)的超高扫描速度可以通过激光二极管和单个模拟微镜在光源中的组合来实现。在恒定偏置条件下,利用激光二极管中5 kHz的交流信号,在8.5秒内对3.2 mm×6.12 mm范围内14×121个点的pH溶液进行u型检测。在500 μm厚硅片上采用10 μm厚Si3N4/3 nm厚SiO2的LAPS系统的图像分辨率为0.0116 mm2,通过衬底更薄的LAPS结构优化可以进一步提高该系统的图像分辨率。通过模拟微镜在LAPS上的应用,证明了一种具有超高扫描速度的化学图像传感器。
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引用次数: 3
Dual high-frequency Surface Acoustic Wave Resonator for ultrafine particle sensing 用于超细粒子传感的双高频表面声波谐振器
Pub Date : 2013-12-19 DOI: 10.1109/ICSENS.2013.6688319
S. Thomas, Z. Rácz, M. Cole, J. Gardner
This paper describes the development of a low-cost robust Surface Acoustic Wave Resonator (SAWR) micro sensor capable of detecting sub-micron size particles below 1 ng. The device comprises two 262 MHz Rayleigh wave SAW resonators fabricated on ST-cut quartz where one is used for particle sensing and the other as a reference channel. Electro-acoustic detection of different particles (including carbon, gold, sucrose, silicon, and PTFE) with different diameters was studied. The mass sensitivity of the SAWR was found to be typically 275 Hz/ng or 4 pg/Hz for the detection of 750 nm diameter gold particles. We believe that the device could be used as a low-cost and low power microsensor for the real-time and ubiquitous monitoring of airborne particulate matter. In particular, our SAWR sensor can be used to detect the typical levels of ultrafine particulate pollutants (PM2.5) found in city air today.
本文描述了一种低成本、鲁棒的表面声波谐振器(SAWR)微传感器的开发,该传感器能够检测小于1ng的亚微米大小的颗粒。该装置包括两个在st切割石英上制造的262 MHz瑞利波SAW谐振器,其中一个用于粒子传感,另一个用作参考通道。研究了不同粒径颗粒(碳、金、蔗糖、硅、聚四氟乙烯)的电声检测。在检测直径为750nm的金颗粒时,发现SAWR的质量灵敏度通常为275 Hz/ng或4 pg/Hz。我们相信,该装置可以作为一种低成本、低功耗的微传感器,用于实时、无所不在的空气颗粒物监测。特别是,我们的SAWR传感器可用于检测当今城市空气中超细颗粒污染物(PM2.5)的典型水平。
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引用次数: 10
A new approach on MEMS sensor batch testing using an analogue parallel test methodology for massive reduction of test time 采用模拟并行测试方法对MEMS传感器进行批量测试,大大缩短了测试时间
Pub Date : 2013-12-19 DOI: 10.1109/ICSENS.2013.6688626
F. Oesterle, R. Weigel, A. Koelpin
With a tremendous shipment increase of MEMS microphones during the last few years, enhanced testing methods have become a key issue for industrial batch manufacturing, focusing on the mechanical sensitivity of the sound transducing diaphragm. Instead of semi-parallel techniques, in which test channels and measurement equipment are duplicated (with a multiplication of invest) for the purpose of further reduction of test time, this paper shows a novel approach for a massive parallel test of MEMS sensors. With several DUTs connected in parallel, the resulting measurements hence reveal several overlain device characteristics, each accounting for the sensitivity of one single DUT. For the specific correlation of those characteristics to each DUT, a reconstruction method known from tomography imaging techniques is adapted. The measurement results on wafer level shown in this paper exhibit the basic suitability of a single test of several DUTs in parallel and prove the concept of this novel method.
近年来,随着MEMS麦克风出货量的大幅增长,增强测试方法已成为工业批量生产的关键问题,重点是声传导隔膜的机械灵敏度。为了进一步减少测试时间,测试通道和测量设备是重复的(投资倍增),而不是半并行技术,本文展示了一种用于大规模并行测试MEMS传感器的新方法。几个被测件并联连接,由此产生的测量结果揭示了几个重叠的设备特性,每个特性都占单个被测件的灵敏度。对于这些特征与每个DUT的特定相关性,采用了断层成像技术中已知的重建方法。本文所示的晶圆级测试结果显示了对多个dut并行进行一次测试的基本适用性,并证明了这种新方法的概念。
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引用次数: 6
期刊
2013 IEEE SENSORS
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