Environmental Pollution最新文献_第10页

Exposure to polyoxyethylene tallow amines (POEAs), glyphosate co-formulation surfactants, in a US pregnant population and their potential endocrine disrupting effects

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-04-04 DOI: 10.1016/j.envpol.2025.126205

Bushra Amreen , Corina Lesseur , Ravikumar Jagani , Shirisha Yelamanchili , Emily S. Barrett , Ruby H.N. Nguyen , Sheela Sathyanarayana , Shanna H. Swan , Syam S. Andra , Jia Chen

Emerging but inconsistent evidence suggests that glyphosate (GLY)-based herbicides (GBHs) are more toxic than the active ingredient, GLY alone. Polyoxyethylene tallow amines (POEAs) are surfactants most widely used in GBH formulations, making up to 5–15 % by weight. However, neither POEA exposure nor their toxicity has been well studied in the general population. This study leverages second trimester urine samples collected from 86 pregnant participants of a multi-center, US-based pregnancy cohort. We measured three POEA homologs, i.e., C₁₆s(EO)₂, C₁₈u(EO)₂, and C₁₈s(EO)₂, using an ultrahigh performance liquid chromatography-tandem with mass spectrometry. These homologs were detected in 79 %, 97 %, and 59 % of the samples (LOD: 0.1 ng/mL) at a mean concentration of 1.87, 1.88, and 1.65 ng/mL, respectively. While these homologs were highly correlated with each other (rho >0.7), their correlations with GLY and its breakdown product, aminomethylphosphonic acid (AMPA), were moderate (rho <0.4). Compared to other races, the POEA level in urine was the lowest in White participants (p = 0.047). We observed an indication that a higher POEA level was associated with increased ano-genital distance (AGD), a marker of gestational androgen milieu, in male infants only (β = 2.46, p = 0.057); such relationship remained unchanged after adjusting for GLY (β = 2.45, p = 0.055) or AMPA (β = 2.46, p = 0.058). Despite the small sample size, our study provides the first population data on POEA exposure which demonstrates widespread exposure in the general population. Suggestive associations between urinary POEA and AGD in male newborns implicate potential endocrine disrupting property of POEA, which warrant further investigation in larger studies.

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引用次数: 0

Pesticide contamination in indoor home dust: A pilot study of non-occupational exposure in Argentina

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-04-04 DOI: 10.1016/j.envpol.2025.126208

Virginia Aparicio , Jessica Kaseker , Paul T.J. Scheepers , Abdallah Alaoui , Daniel M. Figueiredo , Hans Mol , Vera Silva , Paula Harkes , Danilo Rheinheimer Dos Santos , Violette Geissen , José Luis Costa

Agricultural use of pesticides continues to rise globally. Argentina ranks fifth in use. While pesticides help yields, they also pose risks to human health and the environment. Indoor dust can present high pesticide concentrations, raising concerns about chronic exposure in non-farming households. Studies of pesticides in indoor dust are few worldwide. This pioneering study aimed to identify and/or quantify for the first time pesticide occurrence in indoor dust from urban residences in the Pampas Region, southeast of Buenos Aires Province, Argentina. Pesticide residues in indoor dust from 48 non-agricultural homes in the Pampas plain region were analysed. Study participants completed questionnaires on household demographics, pet ownership, pesticide use, gardening, and habits like leaving shoes outside. We detected 41 out of 49 targeted pesticides, including metabolites and banned compounds. Seven of the 49 tested are dual-use compounds (i.e. pesticide & biocide or veterinary applications). The synergist piperonyl butoxide, the dual-use imidacloprid, and “agricultural only” pesticides carbaryl, glyphosate, and atrazine were detected in all dust samples. Glyphosate, 2,4-D, atrazine, imidacloprid, carbaryl, tetramethrin, and piperonyl butoxide had maximum concentrations exceeding 1, 000 μg kg⁻¹. Complex mixtures of up to 32 residues were found per sample. Questionnaire responses revealed that most participants brought shoes inside (60 %), almost all had pets (93 %), and 51 % had used flea repellents (mainly imidacloprid and fipronil). Approximately 48 % reported pesticide use in the past year, and 19 % reported exposure via their (non-farmer) jobs, e.g., via disinfection and weeding. These findings highlight the prevalence of pesticide residues in residential settings and the need for further research on long-term exposure and risks. Improved tracking of agricultural, household, and mixed-use pesticide applications is crucial, particularly in regions heavily reliant on agriculture.

{"title":"Pesticide contamination in indoor home dust: A pilot study of non-occupational exposure in Argentina","authors":"Virginia Aparicio , Jessica Kaseker , Paul T.J. Scheepers , Abdallah Alaoui , Daniel M. Figueiredo , Hans Mol , Vera Silva , Paula Harkes , Danilo Rheinheimer Dos Santos , Violette Geissen , José Luis Costa","doi":"10.1016/j.envpol.2025.126208","DOIUrl":"10.1016/j.envpol.2025.126208","url":null,"abstract":"<div><div>Agricultural use of pesticides continues to rise globally. Argentina ranks fifth in use. While pesticides help yields, they also pose risks to human health and the environment. Indoor dust can present high pesticide concentrations, raising concerns about chronic exposure in non-farming households. Studies of pesticides in indoor dust are few worldwide. This pioneering study aimed to identify and/or quantify for the first time pesticide occurrence in indoor dust from urban residences in the Pampas Region, southeast of Buenos Aires Province, Argentina. Pesticide residues in indoor dust from 48 non-agricultural homes in the Pampas plain region were analysed. Study participants completed questionnaires on household demographics, pet ownership, pesticide use, gardening, and habits like leaving shoes outside. We detected 41 out of 49 targeted pesticides, including metabolites and banned compounds. Seven of the 49 tested are dual-use compounds (i.e. pesticide & biocide or veterinary applications). The synergist piperonyl butoxide, the dual-use imidacloprid, and “agricultural only” pesticides carbaryl, glyphosate, and atrazine were detected in all dust samples. Glyphosate, 2,4-D, atrazine, imidacloprid, carbaryl, tetramethrin, and piperonyl butoxide had maximum concentrations exceeding 1, 000 μg kg<sup>−1</sup>. Complex mixtures of up to 32 residues were found per sample. Questionnaire responses revealed that most participants brought shoes inside (60 %), almost all had pets (93 %), and 51 % had used flea repellents (mainly imidacloprid and fipronil). Approximately 48 % reported pesticide use in the past year, and 19 % reported exposure via their (non-farmer) jobs, e.g., via disinfection and weeding. These findings highlight the prevalence of pesticide residues in residential settings and the need for further research on long-term exposure and risks. Improved tracking of agricultural, household, and mixed-use pesticide applications is crucial, particularly in regions heavily reliant on agriculture.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"373 ","pages":"Article 126208"},"PeriodicalIF":7.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143776080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PFOS exposure impairs porcine oocyte maturation and embryo development via mitochondria-dependent ferroptosis

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-04-04 DOI: 10.1016/j.envpol.2025.126185

Xiaoqing Sun , Ran Teng , Ning Xu , Yutong Sun , Enbo Zhang , Xingfu Chen , Qing Guo , Suo Li

Perfluorooctane sulfonate (PFOS) is a widely utilized chemical known for its exceptional environmental stability over extended periods, its significant potential to bioaccumulate in living organisms, and its considerable risks to both health and the environment. Several studies have suggested that PFOS may pose reproductive risks in mammals; however, the exact mechanisms driving these effects are not well understood. In this study, we explored the possible mechanisms by which PFOS toxicity affects the maturation of mammalian oocytes and the embryonic development employing porcine oocytes as a model system. SMART-seq results suggested that PFOS may affect oocyte maturation through mechanisms involving ferroptosis, autophagy, and alterations in membrane structure. Our results suggest that PFOS exposure adversely affects mitochondrial function and structure, thereby influencing peroxisome biogenesis and contributing to oxidative stress. Most importantly, we found that exposure to PFOS significantly elevated Fe²⁺ levels, an indicator associated with ferroptosis in oocytes. Furthermore, malondialdehyde (MDA) levels in the PFOS group were significantly higher than those in the control group. Additionally, the mRNA expression levels of PCBP1 and PCBP2, which are related to ferroptosis, as well as the expression level of P53, were significantly reduced in the PFOS group. Overall, exposure to PFOS in vitro results in mitochondrial damage in porcine oocytes, which induces lipid peroxidation and subsequently leads to the occurrence of ferroptosis.

{"title":"PFOS exposure impairs porcine oocyte maturation and embryo development via mitochondria-dependent ferroptosis","authors":"Xiaoqing Sun , Ran Teng , Ning Xu , Yutong Sun , Enbo Zhang , Xingfu Chen , Qing Guo , Suo Li","doi":"10.1016/j.envpol.2025.126185","DOIUrl":"10.1016/j.envpol.2025.126185","url":null,"abstract":"<div><div>Perfluorooctane sulfonate (PFOS) is a widely utilized chemical known for its exceptional environmental stability over extended periods, its significant potential to bioaccumulate in living organisms, and its considerable risks to both health and the environment. Several studies have suggested that PFOS may pose reproductive risks in mammals; however, the exact mechanisms driving these effects are not well understood. In this study, we explored the possible mechanisms by which PFOS toxicity affects the maturation of mammalian oocytes and the embryonic development employing porcine oocytes as a model system. SMART-seq results suggested that PFOS may affect oocyte maturation through mechanisms involving ferroptosis, autophagy, and alterations in membrane structure. Our results suggest that PFOS exposure adversely affects mitochondrial function and structure, thereby influencing peroxisome biogenesis and contributing to oxidative stress. Most importantly, we found that exposure to PFOS significantly elevated Fe<sup>2+</sup> levels, an indicator associated with ferroptosis in oocytes. Furthermore, malondialdehyde (MDA) levels in the PFOS group were significantly higher than those in the control group. Additionally, the mRNA expression levels of <em>PCBP1</em> and <em>PCBP2</em>, which are related to ferroptosis, as well as the expression level of P53, were significantly reduced in the PFOS group. Overall, exposure to PFOS in vitro results in mitochondrial damage in porcine oocytes, which induces lipid peroxidation and subsequently leads to the occurrence of ferroptosis.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126185"},"PeriodicalIF":7.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143782809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of atmospheric volatile organic compounds (VOCs) in ozone formation around China's largest plywood manufacturer

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-04-04 DOI: 10.1016/j.envpol.2025.126197

Ningjie Li , Ting Sun , Stephen Mudge , Yuanxun Zhang , Zhenhui Gao , Lihui Huang , Jianing Lin

The volatile organic compounds (VOCs) are a dominant contributor to the formation of ozone (O₃) in Linyi, the plywood capital of China. However, the temporal variations and source origins of VOCs in Linyi remain unclear. This study gathered ambient air samples (n = 214) from the urban center of Linyi during the period April to October of 2021–2023. The total volatile organic compounds (TVOCs) concentrations ranged from 28 ppbv to 32 ppbv with oxygenated volatile organic compounds (OVOCs) taking the large portion (50.76 %) of TVOCs, followed by alkanes (28.11 %), aromatics (13.71 %), alkenes (6.66 %), and alkynes (0.76 %). The OVOCs (44.10 %) were the dominant contributors to ozone formation potential (OFP). Formaldehyde, an OVOC and particular pollutant from plywood industries contributed the most to OFP (∼21.60 %). The average concentration of TVOCs in 2022 was the lowest (28.61 ± 10.76 ppbv), with VOCs species, such as isobutane and propane having the lowest concentrations in 2022 (p < 0.05), reflecting a decrease in transportation activity due to the impacts of pandemic lockdowns. Concentrations of OVOCs were annually increasing because of the annual growth of plywood yield. The TVOCs and OVOCs levels were significantly correlated to O₃ levels (p < 0.01). The concentrations of TVOCs and OVOCs as well as O₃ were highest in June and September (p < 0.05), when the temperature and the degree of photochemical reactions were high. The source apportionment analysis found that plywood industries were the main source (32.90 %) of TVOCs, followed by liquefied petroleum gas (LPG, 21.32 %). Trajectory statistical models (TSM) analysis suggested that Linyi is greatly affected by regional transport from the southwest (31.63 %). This study provides new insights into the mitigation and management of VOCs and O₃ pollution in plywood industry cities.

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引用次数: 0

Physiological and behavioural responses of aquatic organisms to microplastics and experimental warming

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-04-04 DOI: 10.1016/j.envpol.2025.126182

Danielle J. Marchant , Daniel M. Perkins , J. Iwan Jones , Pavel Kratina

Microplastics are an emerging contaminant of concern because of their potential to cause harm to aquatic biota, such as reproduction, growth, and survival, and there is a lack of knowledge about how microplastics can affect other sub-lethal responses, such as movement behaviour and respiration rates, which may have consequences for species interactions. Additionally, there is little evidence for the effects of microplastics under different climate warming scenarios. To address this knowledge gap, the effects of high-density polyethylene (HDPE) microplastics, in combination with different constant temperature regimes (10 °C, 15 °C, and 20 °C) and a fluctuating regime (10–20 °C over a 24h diel cycle) on the respiration rates, feeding rates, and movement speeds of Gammarus pulex and Asellus aquaticus were assessed. Respiration rates of G. pulex increased with temperature according to metabolic theory, but there was no evidence for increased respiration rates of A. aquaticus at higher temperatures. Overall, the respiration rates and movement speeds of G. pulex were higher than A. aquaticus but there was no evidence that microplastics independently, or in combination with experimental warming, influenced any of the responses tested. There is increasing evidence that some microplastic particles may not be harmful to aquatic biota, and the findings presented in this study indicated that further evidence about the effects of different microplastic types, in combination with other human-induced pressures, is required to better understand the hazards and risks associated with microplastic particles in the environment.

{"title":"Physiological and behavioural responses of aquatic organisms to microplastics and experimental warming","authors":"Danielle J. Marchant , Daniel M. Perkins , J. Iwan Jones , Pavel Kratina","doi":"10.1016/j.envpol.2025.126182","DOIUrl":"10.1016/j.envpol.2025.126182","url":null,"abstract":"<div><div>Microplastics are an emerging contaminant of concern because of their potential to cause harm to aquatic biota, such as reproduction, growth, and survival, and there is a lack of knowledge about how microplastics can affect other sub-lethal responses, such as movement behaviour and respiration rates, which may have consequences for species interactions. Additionally, there is little evidence for the effects of microplastics under different climate warming scenarios. To address this knowledge gap, the effects of high-density polyethylene (HDPE) microplastics, in combination with different constant temperature regimes (10 °C, 15 °C, and 20 °C) and a fluctuating regime (10–20 °C over a 24h diel cycle) on the respiration rates, feeding rates, and movement speeds of <em>Gammarus pulex</em> and <em>Asellus aquaticus</em> were assessed. Respiration rates of <em>G. pulex</em> increased with temperature according to metabolic theory, but there was no evidence for increased respiration rates of <em>A. aquaticus</em> at higher temperatures. Overall, the respiration rates and movement speeds of <em>G. pulex</em> were higher than <em>A. aquaticus</em> but there was no evidence that microplastics independently, or in combination with experimental warming, influenced any of the responses tested. There is increasing evidence that some microplastic particles may not be harmful to aquatic biota, and the findings presented in this study indicated that further evidence about the effects of different microplastic types, in combination with other human-induced pressures, is required to better understand the hazards and risks associated with microplastic particles in the environment.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126182"},"PeriodicalIF":7.6,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143776081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antagonism or synergism? Contrasting toxicity mechanisms of combined antibiotic and metal pollution on Eisenia fetida 拮抗还是协同？抗生素和金属联合污染对胎生伊蚊的不同毒性机制

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-04-03 DOI: 10.1016/j.envpol.2025.126166

Qiuyun Xu , Xin Xiong , Yajuan Shi , Li Qian , Xuan Zhou , Xueli Tian , Jinyang Yu , Liuxuan Fang

The pervasive occurrence of combined metal and antibiotic pollution (CMAP) in agricultural soils is increasingly being recognized as a novel threat to ecosystems. However, the toxicity variations of CMAP compared to single pollution and the mechanisms underlying these changes remain poorly understood. Herein in this study, the toxicities of copper (Cu)/erythromycin (ERY) and lead (Pb)/norfloxacin (NOR) to earthworms (Eisenia fetida) were investigated. These results indicated that a single exposure to ERY and NOR at environmental concentrations had negligible effects on physiological processes. Combined Cu/ERY exposure induced more significant oxidative stress, disrupted energy metabolism, and caused cellular damage than Cu alone, as indicated by altered antioxidant enzyme activities, malondialdehyde and adenosine triphosphate content, elevated reactive oxygen species levels, and apoptosis rates in coelomocytes. Conversely, these adverse effects were mitigated by Pb/NOR exposure compared to Pb treatment alone. Further analysis of the gut microbiota revealed that Cu/Pb-tolerant Bacillus spp. play a critical mediating role in the contrasting toxicity profiles. ERY reduced the abundance of Bacillus spp., diminishing their ability to secrete soluble phosphate to immobilize Cu in the gut and leading to increased Cu absorption and toxicity. NOR enriches Bacillus spp. in the gut, facilitating Pb immobilization and reducing Pb bioavailability and toxicity. The contrast toxicity profile revealed the response of the gut microbiota taxa is the primary determinant of the variation in CMAP toxicity. These findings advance our understanding of the impact of CMAP on soil organisms and highlight the need for comprehensive ecological risk assessments to inform regulatory strategies.

人们日益认识到，农业土壤中普遍存在的金属和抗生素联合污染（CMAP）对生态系统构成了新的威胁。然而，与单一污染相比，CMAP 的毒性变化以及导致这些变化的机制仍然鲜为人知。本研究调查了铜（Cu）/红霉素（ERY）和铅（Pb）/诺氟沙星（NOR）对蚯蚓（Eisenia Fetida）的毒性。结果表明，单一暴露于环境浓度的 ERY 和 NOR 对生理过程的影响微乎其微。与单独接触铜相比，联合接触铜/ERY 会诱发更严重的氧化应激，破坏能量代谢，并造成细胞损伤，表现为抗氧化酶活性、丙二醛和三磷酸腺苷含量的改变、活性氧水平的升高以及腹腔细胞的凋亡率。相反，与单独处理铅相比，暴露于铅/NOR可减轻这些不利影响。对肠道微生物群的进一步分析表明，铜/铅耐受性芽孢杆菌属在对比强烈的毒性特征中起着关键的调解作用。ERY降低了芽孢杆菌属的丰度，削弱了它们分泌可溶性磷酸盐以固定肠道中铜的能力，导致铜的吸收和毒性增加。NOR 增加了肠道中芽孢杆菌的数量，促进了铅的固定，降低了铅的生物利用度和毒性。对比毒性特征显示，肠道微生物群分类群的反应是 CMAP 毒性变化的主要决定因素。这些发现加深了我们对 CMAP 对土壤生物影响的理解，并强调了进行全面生态风险评估的必要性，以便为监管策略提供依据。

{"title":"Antagonism or synergism? Contrasting toxicity mechanisms of combined antibiotic and metal pollution on Eisenia fetida","authors":"Qiuyun Xu , Xin Xiong , Yajuan Shi , Li Qian , Xuan Zhou , Xueli Tian , Jinyang Yu , Liuxuan Fang","doi":"10.1016/j.envpol.2025.126166","DOIUrl":"10.1016/j.envpol.2025.126166","url":null,"abstract":"<div><div>The pervasive occurrence of combined metal and antibiotic pollution (CMAP) in agricultural soils is increasingly being recognized as a novel threat to ecosystems. However, the toxicity variations of CMAP compared to single pollution and the mechanisms underlying these changes remain poorly understood. Herein in this study, the toxicities of copper (Cu)/erythromycin (ERY) and lead (Pb)/norfloxacin (NOR) to earthworms (<em>Eisenia fetida</em>) were investigated. These results indicated that a single exposure to ERY and NOR at environmental concentrations had negligible effects on physiological processes. Combined Cu/ERY exposure induced more significant oxidative stress, disrupted energy metabolism, and caused cellular damage than Cu alone, as indicated by altered antioxidant enzyme activities, malondialdehyde and adenosine triphosphate content, elevated reactive oxygen species levels, and apoptosis rates in coelomocytes. Conversely, these adverse effects were mitigated by Pb/NOR exposure compared to Pb treatment alone. Further analysis of the gut microbiota revealed that Cu/Pb-tolerant <em>Bacillus</em> spp. play a critical mediating role in the contrasting toxicity profiles. ERY reduced the abundance of <em>Bacillus</em> spp., diminishing their ability to secrete soluble phosphate to immobilize Cu in the gut and leading to increased Cu absorption and toxicity. NOR enriches <em>Bacillus</em> spp. in the gut, facilitating Pb immobilization and reducing Pb bioavailability and toxicity. The contrast toxicity profile revealed the response of the gut microbiota taxa is the primary determinant of the variation in CMAP toxicity. These findings advance our understanding of the impact of CMAP on soil organisms and highlight the need for comprehensive ecological risk assessments to inform regulatory strategies.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126166"},"PeriodicalIF":7.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modelling Escherichia coli concentrations: 45.6 %–78.1 % of China's rivers show poor microbial water quality

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-04-03 DOI: 10.1016/j.envpol.2025.126184

Songtao Mei , Kai Wang , Heike Schmitt , Nynke Hofstra

Water quality is under threat due to the presence of pathogenic and antibiotic-resistant bacteria. Escherichia coli (E. coli) serves as an indicator of faecal contamination and the potential presence of other harmful pathogens. Understanding E. coli concentrations helps in assessing the overall health risks associated with waterborne diseases and developing effective water management strategies. Therefore, we developed the first large-scale model, GloWPa-Ecoli C1 to simulate E. coli loads and concentrations in rivers and apply this model to China. The model provides the first comprehensive overview of microbial water quality across China's rivers. The model simulates E. coli concentrations in 2020 to range from 10^−1.2 to 10^6.3 CFU/L, with 45.6 %–78.1 % of rivers exhibiting poor microbial water quality. Major hotspots of E. coli pollution are Haihe, Huaihe and Pearl River Basins. Direct discharge of human faecal waste contributes 80.2 % of the total E. coli load, while directly discharged livestock waste accounts for 13.1 %. To mitigate E. coli pollution in rivers in China, we recommend increasing human faecal waste collection rates, expanding wastewater treatment plant (WWTP) coverage, phasing out primary treatment WWTPs and eliminating direct livestock faecal waste discharge, particularly from smallholder farms. The study underscores the urgent need to improve microbial water quality in China's rivers. The findings provide actionable insights to inform policy development aimed at safeguarding water quality and public health. Furthermore, the modelling approach is applicable to other regions and microorganisms, offering a foundation for developing models to address antibiotic-resistant bacteria and other emerging water quality challenges.

{"title":"Modelling Escherichia coli concentrations: 45.6 %–78.1 % of China's rivers show poor microbial water quality","authors":"Songtao Mei , Kai Wang , Heike Schmitt , Nynke Hofstra","doi":"10.1016/j.envpol.2025.126184","DOIUrl":"10.1016/j.envpol.2025.126184","url":null,"abstract":"<div><div>Water quality is under threat due to the presence of pathogenic and antibiotic-resistant bacteria. <em>Escherichia coli</em> (<em>E. coli</em>) serves as an indicator of faecal contamination and the potential presence of other harmful pathogens. Understanding <em>E. coli</em> concentrations helps in assessing the overall health risks associated with waterborne diseases and developing effective water management strategies. Therefore, we developed the first large-scale model, GloWPa-Ecoli C1 to simulate <em>E. coli</em> loads and concentrations in rivers and apply this model to China. The model provides the first comprehensive overview of microbial water quality across China's rivers. The model simulates <em>E. coli</em> concentrations in 2020 to range from 10<sup>−1.2</sup> to 10<sup>6.3</sup> CFU/L, with 45.6 %–78.1 % of rivers exhibiting poor microbial water quality. Major hotspots of <em>E. coli</em> pollution are Haihe, Huaihe and Pearl River Basins. Direct discharge of human faecal waste contributes 80.2 % of the total <em>E. coli</em> load, while directly discharged livestock waste accounts for 13.1 %. To mitigate <em>E. coli</em> pollution in rivers in China, we recommend increasing human faecal waste collection rates, expanding wastewater treatment plant (WWTP) coverage, phasing out primary treatment WWTPs and eliminating direct livestock faecal waste discharge, particularly from smallholder farms. The study underscores the urgent need to improve microbial water quality in China's rivers. The findings provide actionable insights to inform policy development aimed at safeguarding water quality and public health. Furthermore, the modelling approach is applicable to other regions and microorganisms, offering a foundation for developing models to address antibiotic-resistant bacteria and other emerging water quality challenges.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126184"},"PeriodicalIF":7.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143776043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of polystyrene microparticles exposures on spermatogenic cell differentiation and reproductive endpoints in male mice

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-04-03 DOI: 10.1016/j.envpol.2025.126200

Rong Shen , Peng Xia , Yanan Guo , Pengfei Ji , Xinyi Yuan , Lu Wang , Si Shuang , Liwei Zhou , Ruizhi Tong , Lijuan Zhang , Disheng Liu , Degui Wang

The widespread distribution of microplastics in the environment has raised concerns about their potential implications for human health. Microplastics accumulate in animals and humans, but the risks associated with these pollutants are not fully understood. This study aimed to investigate the effects of polystyrene microplastics on the male reproductive system. The 0.1 μm polystyrene (PS) could accumulate in the testicular tissue and spermatogonia GC-1, while 1 μm PS was not easy to enter and accumulate in the testicular tissue and cells. Mice continuously exposed for 3-months to 0.1 μm PS demonstrated lower fertility and inhibited spermatogonium differentiation compared to control mice. The 0.1 μm PS were dispersed throughout the seminiferous tubule of the testis. Metabolic reprogramming was found to be involved in these processes. Histone methylation and autophagy-related pathways showed significant differences following PS treatment in testis tissue and GC-1 cells. Our findings suggest that chronic exposure to 0.1 μm PS inhibited spermatogenic cell differentiation and impaired fertility in male mice. We propose that abnormal epigenetic modifications in 0.1 μm PS exposed mice contributed to the dysregulation of glycolytic enzymes, and that the impaired autophagic pathway exacerbated the accumulation of glycolytic enzymes further. Glycolysis plays a critical role in the regulation of spermatogenic cell differentiation, and its regulation partially alleviated the impairments associated with PS exposure. In conclusion, our findings suggest that chronic exposure to nanoplastics PS inhibited spermatogenic cell differentiation and impaired fertility in male mice via disrupted epigenetic modification and metabolic dysregulation.

{"title":"Effects of polystyrene microparticles exposures on spermatogenic cell differentiation and reproductive endpoints in male mice","authors":"Rong Shen , Peng Xia , Yanan Guo , Pengfei Ji , Xinyi Yuan , Lu Wang , Si Shuang , Liwei Zhou , Ruizhi Tong , Lijuan Zhang , Disheng Liu , Degui Wang","doi":"10.1016/j.envpol.2025.126200","DOIUrl":"10.1016/j.envpol.2025.126200","url":null,"abstract":"<div><div>The widespread distribution of microplastics in the environment has raised concerns about their potential implications for human health. Microplastics accumulate in animals and humans, but the risks associated with these pollutants are not fully understood. This study aimed to investigate the effects of polystyrene microplastics on the male reproductive system. The 0.1 μm polystyrene (PS) could accumulate in the testicular tissue and spermatogonia GC-1, while 1 μm PS was not easy to enter and accumulate in the testicular tissue and cells. Mice continuously exposed for 3-months to 0.1 μm PS demonstrated lower fertility and inhibited spermatogonium differentiation compared to control mice. The 0.1 μm PS were dispersed throughout the seminiferous tubule of the testis. Metabolic reprogramming was found to be involved in these processes. Histone methylation and autophagy-related pathways showed significant differences following PS treatment in testis tissue and GC-1 cells. Our findings suggest that chronic exposure to 0.1 μm PS inhibited spermatogenic cell differentiation and impaired fertility in male mice. We propose that abnormal epigenetic modifications in 0.1 μm PS exposed mice contributed to the dysregulation of glycolytic enzymes, and that the impaired autophagic pathway exacerbated the accumulation of glycolytic enzymes further. Glycolysis plays a critical role in the regulation of spermatogenic cell differentiation, and its regulation partially alleviated the impairments associated with PS exposure. In conclusion, our findings suggest that chronic exposure to nanoplastics PS inhibited spermatogenic cell differentiation and impaired fertility in male mice via disrupted epigenetic modification and metabolic dysregulation.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"373 ","pages":"Article 126200"},"PeriodicalIF":7.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sulfidated zero-valent iron bimetals for passive remediation of chlorinated vapors in the subsurface 硫化零价双金属用于被动修复地下氯化蒸汽

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-04-03 DOI: 10.1016/j.envpol.2025.126202

Clarissa Settimi, Daniela Zingaretti, Iason Verginelli, Renato Baciocchi

This study explores a novel application of sulfidated zero-valent iron (S-ZVI) bimetals for the treatment of chlorinated solvents in the vapor phase. The potential of these reactive materials was investigated through batch, column, and modeling tests. The materials were produced by disc milling of ZVI, sulfur (S), copper (Cu), and nickel (Ni) with molar ratios of 0.05 and 0.2. The reactivity of the materials was assessed through vapor degradation batch tests conducted under partially saturated conditions using trichloroethylene (TCE) as a model compound. Sulfidated materials with a 0.05 S/ZVI molar ratio were the most reactive, achieving up to 99 % degradation of TCE vapors within 18 h and first-order degradation constants of 5–5.7 d⁻¹. Compared to the non-sulfidated materials, sulfidated ones remained reactive even after aging by exposure to air for 30 days. In all tests, C₃-C₆ hydrocarbons were detected as main byproducts, indicating β-elimination as the dominant TCE degradation pathway, with minor dichloroethylene and vinyl chloride amounts from the hydrogenolysis pathway. To evaluate the use of sulfidated bimetals as Horizontal Permeable Reactive Barriers (HPRBs) for treating chlorinated vapors in the subsurface, TCE diffusion column tests were performed using a 5 cm thick reactive layer of S-ZVI-Ni. These tests demonstrated up to 70 % degradation over 25 days. By integrating the column test results into an analytical model, it was estimated that an 18 cm HPRB could ensure up to 99 % degradation of TCE vapors. These findings highlight the potential of S-ZVI bimetals as an effective passive mitigation system for reducing chlorinated solvent vapor emissions from the subsurface.

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引用次数: 0

Distribution and characteristics of microplastics in fluvial sediments from the Koshi River Basin, Nepal 尼泊尔甲西河流域冲积沉积物中微塑料的分布与特征

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-04-03 DOI: 10.1016/j.envpol.2025.126189

Alisha Dahal , Bishal Dahal , Sagar Sitaula , Rupesh Bohara , Ramesh Raj Pant , Yukti Acharya , Khaga Raj Sharma , Basant Giri , Bhanu Bhakta Neupane

Microplastics (MPs) are emerging contaminants found in various ecosystems including oceans, lakes, rivers, sediment, air, and soil. Mapping of MPs in different deposition zones in fresh water sediment is important to identify their potential sources, sink, and transport mechanism. In this study, MPs were analyzed in sediment samples from Arun, Tamor, and Koshi Rivers in eastern Nepal. A total of 78 samples from 26 sites were collected from three independent deposition regions i.e., recent deposition (R0), recent past deposition (R1), and past deposition (R2) during monsoon season in 2023. All samples were analyzed following standard methods involving drying, peroxidation, density separation, microscopic examination and chemical identification by FTIR. In all the river basins differences in MPs count, color, and morphology were observed in three deposition regions. In Koshi basin the MPs count ranged from 7016–8876 MPKg^–¹, 8396–10596 MPKg^–¹, and 9416–9816 MPKg^–¹ in R2, R1 and R0 regions, respectively. The mean abundance was found to be higher in downstream especially in Koshi River. The predominant shapes, sizes, and colors found in all three river basins were fragment (52.5 %), 20–100 μm (58.86 %), and black (33.76 %). The particles were identified as polyamide, polypropylene, polyvinyl chloride, polysulfone, nylon, and polyether ether ketone. The pollution risk assessment indicated minimal MPs contamination upstream and moderate contamination downstream. Finally, principal component analysis (PCA) and land use and land cover change (LULC) data were utilized to identify the potential sources of MPs. Agricultural and anthropogenic sources were identified as major contributors to the MPs load. This study provides baseline data for MP concentrations and their potential sources in Arun, Tamor, and Koshi river sediments. These insights could be important for future MPs mitigation strategies.

{"title":"Distribution and characteristics of microplastics in fluvial sediments from the Koshi River Basin, Nepal","authors":"Alisha Dahal , Bishal Dahal , Sagar Sitaula , Rupesh Bohara , Ramesh Raj Pant , Yukti Acharya , Khaga Raj Sharma , Basant Giri , Bhanu Bhakta Neupane","doi":"10.1016/j.envpol.2025.126189","DOIUrl":"10.1016/j.envpol.2025.126189","url":null,"abstract":"<div><div>Microplastics (MPs) are emerging contaminants found in various ecosystems including oceans, lakes, rivers, sediment, air, and soil. Mapping of MPs in different deposition zones in fresh water sediment is important to identify their potential sources, sink, and transport mechanism. In this study, MPs were analyzed in sediment samples from Arun, Tamor, and Koshi Rivers in eastern Nepal. A total of 78 samples from 26 sites were collected from three independent deposition regions i.e., recent deposition (R0), recent past deposition (R1), and past deposition (R2) during monsoon season in 2023. All samples were analyzed following standard methods involving drying, peroxidation, density separation, microscopic examination and chemical identification by FTIR. In all the river basins differences in MPs count, color, and morphology were observed in three deposition regions. In Koshi basin the MPs count ranged from 7016–8876 MPKg<sup>–</sup><sup>1</sup>, 8396–10596 MPKg<sup>–</sup><sup>1</sup>, and 9416–9816 MPKg<sup>–</sup><sup>1</sup> in R2, R1 and R0 regions, respectively. The mean abundance was found to be higher in downstream especially in Koshi River. The predominant shapes, sizes, and colors found in all three river basins were fragment (52.5 %), 20–100 μm (58.86 %), and black (33.76 %). The particles were identified as polyamide, polypropylene, polyvinyl chloride, polysulfone, nylon, and polyether ether ketone. The pollution risk assessment indicated minimal MPs contamination upstream and moderate contamination downstream. Finally, principal component analysis (PCA) and land use and land cover change (LULC) data were utilized to identify the potential sources of MPs. Agricultural and anthropogenic sources were identified as major contributors to the MPs load. This study provides baseline data for MP concentrations and their potential sources in Arun, Tamor, and Koshi river sediments. These insights could be important for future MPs mitigation strategies.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"374 ","pages":"Article 126189"},"PeriodicalIF":7.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0