Environmental Pollution最新文献_第7页

Distinct responses of Caenorhabditis elegans to polyethylene microplastics and plant secondary metabolites

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-03-12 DOI: 10.1016/j.envpol.2025.126051

Yi Wang , Wanxin Liu , Ziwei Chen , Kaixin Zheng , Xianliang Yi , Jiao Wang , Xiaochen Chen , Xianhua Liu

Soil worms are among the most abundant and functionally diverse soil animals. However, they have been largely overlooked in studies on microplastic (MP) toxicity. MPs and plant secondary metabolites (PSMs) are ubiquitous in soil due to plant litter decomposition and heavy MP contamination, inevitably interacting and exerting combined toxicity on soil organisms. However, little research has been conducted on their joint effects. This study investigates the individual and combined toxic effects of polyethylene (PE) MPs and three PSMs (glycyrrhizic acid, tannic acid, and matrine) on the model organism Caenorhabditis elegans. Physiological and biochemical responses were assessed using fluorescence microscopy, image analysis, and statistical methods. After 42 h of exposure to PE MPs and/or PSMs, worm growth and development were negatively impacted. Under experimental conditions, matrine and PE MPs synergistically inhibited worm growth, exacerbated neurological damage, and induced oxidative stress. In contrast, glycyrrhizic acid and tannic acid alleviated PE MP-induced growth inhibition, mitigated oxidative stress, and demonstrated antioxidant properties that counteracted oxidative damage. This study offers new insights into the combined effects of MPs and PSMs in soil ecosystems, contributing to ecological risk assessments and pollution management strategies.

{"title":"Distinct responses of Caenorhabditis elegans to polyethylene microplastics and plant secondary metabolites","authors":"Yi Wang , Wanxin Liu , Ziwei Chen , Kaixin Zheng , Xianliang Yi , Jiao Wang , Xiaochen Chen , Xianhua Liu","doi":"10.1016/j.envpol.2025.126051","DOIUrl":"10.1016/j.envpol.2025.126051","url":null,"abstract":"<div><div>Soil worms are among the most abundant and functionally diverse soil animals. However, they have been largely overlooked in studies on microplastic (MP) toxicity. MPs and plant secondary metabolites (PSMs) are ubiquitous in soil due to plant litter decomposition and heavy MP contamination, inevitably interacting and exerting combined toxicity on soil organisms. However, little research has been conducted on their joint effects. This study investigates the individual and combined toxic effects of polyethylene (PE) MPs and three PSMs (glycyrrhizic acid, tannic acid, and matrine) on the model organism <em>Caenorhabditis elegans</em>. Physiological and biochemical responses were assessed using fluorescence microscopy, image analysis, and statistical methods. After 42 h of exposure to PE MPs and/or PSMs, worm growth and development were negatively impacted. Under experimental conditions, matrine and PE MPs synergistically inhibited worm growth, exacerbated neurological damage, and induced oxidative stress. In contrast, glycyrrhizic acid and tannic acid alleviated PE MP-induced growth inhibition, mitigated oxidative stress, and demonstrated antioxidant properties that counteracted oxidative damage. This study offers new insights into the combined effects of MPs and PSMs in soil ecosystems, contributing to ecological risk assessments and pollution management strategies.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126051"},"PeriodicalIF":7.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urban trace metal contamination is negatively associated with condition and wing morphology in a common waterbird

IF 8.9 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-03-12 DOI: 10.1016/j.envpol.2025.126046

Piotr Minias, Marcin Markowski, Mirosława Słaba, Amelia Chyb, Joanna Drzewińska-Chańko, Jan Jedlikowski, Jerzy Bańbura, Radosław Włodarczyk

Urban areas suffer from different forms of environmental pollution by light, noise, and chemicals. Pollution by trace metals has long been associated with industrialization and urbanization processes, increasing the risk of bioaccumulation and compromising the health, condition, and fitness of urban animals. Here, we aimed to investigate the effects of urbanization on bioaccumulation of six trace metals (Cu, Ni, Zn, Cd, Pb, and Mn) in the integumentary structures (feathers) of a non-passerine waterbird, the Eurasian coot (Fulica atra). For this purpose, we quantified and compared trace metal concentrations in feathers of 300 coots from four pairs of non-urban and urban populations associated with major agglomerations in Poland. We found that concentrations of three trace metals (Cu, Ni, and Zn) were significantly higher in coots from the urban landscape, compared to individuals from natural or semi-natural non-urban habitats. Elevated trace metal concentrations were negatively associated with morphology (wing length) and condition (body mass and blood haemoglobin concentration) of coots, and these associations were detected exclusively in the urban landscape. There was limited evidence of elevated trace metal pollution in the non-urban landscape (only Cd) and only weak support for a negative association of Pb concentration with physiological stress of non-urban coots. Our results suggest that trace metal contamination may be considered an important cost of urbanization processes in wildlife. We argue that mitigation of trace metal pollution in urban ecosystems should likely increase their sustainability and viability of urban animal populations.

{"title":"Urban trace metal contamination is negatively associated with condition and wing morphology in a common waterbird","authors":"Piotr Minias, Marcin Markowski, Mirosława Słaba, Amelia Chyb, Joanna Drzewińska-Chańko, Jan Jedlikowski, Jerzy Bańbura, Radosław Włodarczyk","doi":"10.1016/j.envpol.2025.126046","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.126046","url":null,"abstract":"Urban areas suffer from different forms of environmental pollution by light, noise, and chemicals. Pollution by trace metals has long been associated with industrialization and urbanization processes, increasing the risk of bioaccumulation and compromising the health, condition, and fitness of urban animals. Here, we aimed to investigate the effects of urbanization on bioaccumulation of six trace metals (Cu, Ni, Zn, Cd, Pb, and Mn) in the integumentary structures (feathers) of a non-passerine waterbird, the Eurasian coot (<em>Fulica atra</em>). For this purpose, we quantified and compared trace metal concentrations in feathers of 300 coots from four pairs of non-urban and urban populations associated with major agglomerations in Poland. We found that concentrations of three trace metals (Cu, Ni, and Zn) were significantly higher in coots from the urban landscape, compared to individuals from natural or semi-natural non-urban habitats. Elevated trace metal concentrations were negatively associated with morphology (wing length) and condition (body mass and blood haemoglobin concentration) of coots, and these associations were detected exclusively in the urban landscape. There was limited evidence of elevated trace metal pollution in the non-urban landscape (only Cd) and only weak support for a negative association of Pb concentration with physiological stress of non-urban coots. Our results suggest that trace metal contamination may be considered an important cost of urbanization processes in wildlife. We argue that mitigation of trace metal pollution in urban ecosystems should likely increase their sustainability and viability of urban animal populations.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"183 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143608178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Organic matter content, source, and composition varying with seasons and anthropogenic activities regulate methylmercury dynamics in the Yellow River

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-03-12 DOI: 10.1016/j.envpol.2025.126042

Xiaoquan Liu , Yingjun Wang , Xiaomeng Ji , Qingzhe Zhang , Yue Song , Yanbin Li , Yongguang Yin , Yong Cai

Organic matter (OM) in rivers, influenced by natural and anthropogenic events, plays a critical role in regulating methylmercury (MeHg) dynamics. This study investigated the spatial-temporal patterns of MeHg and OM in the Yellow River, through collecting water and sediment samples within the dry and wet seasons and human-induced water-sediment regulation scheme (WSRS) event. During the wet season, the river water was characterized by terrigenous OM, high unfiltered MeHg (UMeHg) concentration (206 ± 83.6 pg/L), and a low UMeHg percentage in unfiltered total Hg (UTHg) (UMeHg/UTHg = 0.37 ± 0.18 %). These findings may suggest that MeHg in the wet season was likely produced in the catchment and imported into the river. In contrast, autochthonous OM predominated during the dry season, probably enhancing in situ MeHg production (UMeHg/UTHg = 1.01 ± 0.50 %), although UMeHg concentration was lower (81.8 ± 25.5 pg/L) due to obviously reduced external inputs. The WSRS dramatically increased water MeHg contents (589 ± 116 pg/L) and UMeHg/UTHg ratios (0.78 ± 0.16 %) probably through direct inputs of upstream reservoirs’ MeHg and resuspension of downstream sediments. Exploring the effects of OM on sediment MeHg sources suggested that MeHg in the wet season primarily originated from watershed soil inputs, while in the dry season, it mainly resulted from in situ Hg methylation. However, extremely low total Hg (THg) and MeHg/THg (0.02–0.35 %) indicated that sediment MeHg production may be of minor importance in the Yellow River.

{"title":"Organic matter content, source, and composition varying with seasons and anthropogenic activities regulate methylmercury dynamics in the Yellow River","authors":"Xiaoquan Liu , Yingjun Wang , Xiaomeng Ji , Qingzhe Zhang , Yue Song , Yanbin Li , Yongguang Yin , Yong Cai","doi":"10.1016/j.envpol.2025.126042","DOIUrl":"10.1016/j.envpol.2025.126042","url":null,"abstract":"<div><div>Organic matter (OM) in rivers, influenced by natural and anthropogenic events, plays a critical role in regulating methylmercury (MeHg) dynamics. This study investigated the spatial-temporal patterns of MeHg and OM in the Yellow River, through collecting water and sediment samples within the dry and wet seasons and human-induced water-sediment regulation scheme (WSRS) event. During the wet season, the river water was characterized by terrigenous OM, high unfiltered MeHg (UMeHg) concentration (206 ± 83.6 pg/L), and a low UMeHg percentage in unfiltered total Hg (UTHg) (UMeHg/UTHg = 0.37 ± 0.18 %). These findings may suggest that MeHg in the wet season was likely produced in the catchment and imported into the river. In contrast, autochthonous OM predominated during the dry season, probably enhancing <em>in situ</em> MeHg production (UMeHg/UTHg = 1.01 ± 0.50 %), although UMeHg concentration was lower (81.8 ± 25.5 pg/L) due to obviously reduced external inputs. The WSRS dramatically increased water MeHg contents (589 ± 116 pg/L) and UMeHg/UTHg ratios (0.78 ± 0.16 %) probably through direct inputs of upstream reservoirs’ MeHg and resuspension of downstream sediments. Exploring the effects of OM on sediment MeHg sources suggested that MeHg in the wet season primarily originated from watershed soil inputs, while in the dry season, it mainly resulted from <em>in situ</em> Hg methylation. However, extremely low total Hg (THg) and MeHg/THg (0.02–0.35 %) indicated that sediment MeHg production may be of minor importance in the Yellow River.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126042"},"PeriodicalIF":7.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143608176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tracing acid mine drainage from an accidental spill on the Estuary of Huelva (SW Spain)

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-03-12 DOI: 10.1016/j.envpol.2025.126033

Rafael Pérez-López , Carlos R. Cánovas , Francisco Macías , M. Dolores Basallote , Rémi Freydier , Manuel Olías , José Miguel Nieto

The Estuary of Huelva in southwestern Spain is severely impacted by acid mine drainage (AMD), primarily due to extensive mining activities in the Iberian Pyrite Belt (IPB), and to a lesser extent by industrial sources. The AMD has led to significant contamination of the Odiel and Tinto rivers, which carry high loads of metals into the estuary. In May 2017, an accidental spill occurred at La Zarza mine, releasing approximately 270,000 m³ of acidic water contained in a pit lake. This event increased the contamination levels in the Odiel River and subsequently in the Estuary of Huelva and the Atlantic Ocean. The current focus of our investigation is to understand the geochemical behavior of contaminants during estuarine mixing and evaluate the environmental impact of the spill, from the river to the littoral. Key findings include the chronic exposure of the estuary to mining pollutants, with specific contaminants escaping retention processes and altering the metal background levels in the Gulf of Cádiz. This study highlights the need for effective control measures in historical abandoned mining districts worldwide to prevent similar environmental disasters in the future.

{"title":"Tracing acid mine drainage from an accidental spill on the Estuary of Huelva (SW Spain)","authors":"Rafael Pérez-López , Carlos R. Cánovas , Francisco Macías , M. Dolores Basallote , Rémi Freydier , Manuel Olías , José Miguel Nieto","doi":"10.1016/j.envpol.2025.126033","DOIUrl":"10.1016/j.envpol.2025.126033","url":null,"abstract":"<div><div>The Estuary of Huelva in southwestern Spain is severely impacted by acid mine drainage (AMD), primarily due to extensive mining activities in the Iberian Pyrite Belt (IPB), and to a lesser extent by industrial sources. The AMD has led to significant contamination of the Odiel and Tinto rivers, which carry high loads of metals into the estuary. In May 2017, an accidental spill occurred at La Zarza mine, releasing approximately 270,000 m<sup>3</sup> of acidic water contained in a pit lake. This event increased the contamination levels in the Odiel River and subsequently in the Estuary of Huelva and the Atlantic Ocean. The current focus of our investigation is to understand the geochemical behavior of contaminants during estuarine mixing and evaluate the environmental impact of the spill, from the river to the littoral. Key findings include the chronic exposure of the estuary to mining pollutants, with specific contaminants escaping retention processes and altering the metal background levels in the Gulf of Cádiz. This study highlights the need for effective control measures in historical abandoned mining districts worldwide to prevent similar environmental disasters in the future.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126033"},"PeriodicalIF":7.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143608422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elevated levels of tritium in surface water collected in the immediate aftermath of the Fukushima accident

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-03-11 DOI: 10.1016/j.envpol.2025.126040

Khemruthai Kheamsiri , Donovan Anderson , Hirofumi Tazoe , Kazusa Okada , Nao Otashiro , Haruka Kuwata , Hideki Kakiuchi , Masahiro Hosoda , Tibor Kovács , Shinji Tokonami , Naofumi Akata

The Fukushima Daiichi Nuclear Power Plant (FDNPP) accident in 2011, triggered by the Tohoku earthquake and tsunami, released a substantial amount of radionuclides into the environment, including approximately 2.7 PBq of ¹³⁷Cs and 200–210 TBq of tritium (³H). While extensive research has reported ¹³⁷Cs concentrations across various environmental media, data on ³H levels in water resources immediately following the accident remain limited. This study examines ³H concentrations in terrestrial surface water collected from one week to 100 days post-accident. ³H concentrations ranged from 0.3 to 267.8 Bq L⁻¹, with the highest levels exceeding typical background concentrations (0.5–2 Bq L⁻¹) by a factor of 200. The highest ³H concentration (267.8 Bq L⁻¹) was measured in snowmelt collected 100 km from the FDNPP one week after the accident, suggesting that snowfall effectively deposited atmospheric ³H. By one-month post-accident, all surface water samples showed ³H levels consistent with natural background concentrations, indicating rapid dispersion and dilution. No correlation was found between ¹³⁷Cs and ³H concentrations, likely due to their differing deposition mechanisms and environmental behaviors. An annual effective dose estimation, based on the ingestion of the most contaminated sample (snowmelt), was 3.5 × 10⁻³ Sv y⁻¹—286 times lower than the 1 mSv annual dose limit for the general public.

{"title":"Elevated levels of tritium in surface water collected in the immediate aftermath of the Fukushima accident","authors":"Khemruthai Kheamsiri , Donovan Anderson , Hirofumi Tazoe , Kazusa Okada , Nao Otashiro , Haruka Kuwata , Hideki Kakiuchi , Masahiro Hosoda , Tibor Kovács , Shinji Tokonami , Naofumi Akata","doi":"10.1016/j.envpol.2025.126040","DOIUrl":"10.1016/j.envpol.2025.126040","url":null,"abstract":"<div><div>The Fukushima Daiichi Nuclear Power Plant (FDNPP) accident in 2011, triggered by the Tohoku earthquake and tsunami, released a substantial amount of radionuclides into the environment, including approximately 2.7 PBq of <sup>137</sup>Cs and 200–210 TBq of tritium (<sup>3</sup>H). While extensive research has reported <sup>137</sup>Cs concentrations across various environmental media, data on <sup>3</sup>H levels in water resources immediately following the accident remain limited. This study examines <sup>3</sup>H concentrations in terrestrial surface water collected from one week to 100 days post-accident. <sup>3</sup>H concentrations ranged from 0.3 to 267.8 Bq L<sup>−1</sup>, with the highest levels exceeding typical background concentrations (0.5–2 Bq L<sup>−1</sup>) by a factor of 200. The highest <sup>3</sup>H concentration (267.8 Bq L<sup>−1</sup>) was measured in snowmelt collected 100 km from the FDNPP one week after the accident, suggesting that snowfall effectively deposited atmospheric <sup>3</sup>H. By one-month post-accident, all surface water samples showed <sup>3</sup>H levels consistent with natural background concentrations, indicating rapid dispersion and dilution. No correlation was found between <sup>137</sup>Cs and <sup>3</sup>H concentrations, likely due to their differing deposition mechanisms and environmental behaviors. An annual effective dose estimation, based on the ingestion of the most contaminated sample (snowmelt), was 3.5 × 10<sup>−3</sup> Sv y<sup>−1</sup>—286 times lower than the 1 mSv annual dose limit for the general public.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126040"},"PeriodicalIF":7.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Ecotoxicological effects of Diclofenac and Gentamicin on Mytilus galloprovincialis: What Does In Vivo Reveal That In Vitro Fails to Show?

IF 8.9 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-03-11 DOI: 10.1016/j.envpol.2025.126045

Afonso Pereira, Marta Cunha, Alessia Cuccaro, Hugo C. Vieira, Yide He, Amadeu M.V.M. Soares, Rosa Freitas

This study investigated the toxicological effects of diclofenac (DIC) and gentamicin (GEN) on the gills (G) and digestive gland (DG) of Mytilus galloprovincialis through in vitro and in vivo assays. Biochemical markers related to oxidative stress, metabolic capacity and neurotoxicity were evaluated at the end of each assay. For both assays, Principal coordinates analysis (PCO) highlighted distinct biochemical profiles between G and DG, mostly related to higher basal values for several biomarkers in DG. Integrated Biomarker Response (IBR) Index revealed higher scores in G for the in vitro assay, especially after exposure to GEN. In the in vivo assay the highest scores were recorded in DG, especially in the presence of DIC. The distinct responses of G and DG underscore their roles in respiration and detoxification, with G being more sensitive to acute stress and DG exhibiting greater adaptive capacity over time. Furthermore, it appears that GEN caused the greatest impact on G after the in vitro assay, while DIC had the most significant effect on DG following the in vivo experiment. In vitro assays demonstrated limited oxidative stress and cellular damage, while in vivo results highlighted substantial metabolic depression and biomarker variability under prolonged exposure. When analyzed individually, the in vitro assay showed a clearer distinction between the two contaminants, especially in the DG. The findings underscore the differential vulnerability and adaptive capacities of G and DG, attributed to their respective roles in respiration and detoxification. These results emphasize the complementary nature of in vitro and in vivo approaches, with the former providing mechanistic insights and the latter reflecting systemic organismal responses. This study highlights the importance of a multi-dimensional approach, combining both in vitro and in vivo methodologies, to better understand tissue-specific toxicity and the broader ecological consequences of pharmaceutical contamination.

{"title":"The Ecotoxicological effects of Diclofenac and Gentamicin on Mytilus galloprovincialis: What Does In Vivo Reveal That In Vitro Fails to Show?","authors":"Afonso Pereira, Marta Cunha, Alessia Cuccaro, Hugo C. Vieira, Yide He, Amadeu M.V.M. Soares, Rosa Freitas","doi":"10.1016/j.envpol.2025.126045","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.126045","url":null,"abstract":"This study investigated the toxicological effects of diclofenac (DIC) and gentamicin (GEN) on the gills (G) and digestive gland (DG) of <em>Mytilus galloprovincialis</em> through <em>in vitro</em> and <em>in vivo</em> assays. Biochemical markers related to oxidative stress, metabolic capacity and neurotoxicity were evaluated at the end of each assay. For both assays, Principal coordinates analysis (PCO) highlighted distinct biochemical profiles between G and DG, mostly related to higher basal values for several biomarkers in DG. Integrated Biomarker Response (IBR) Index revealed higher scores in G for the <em>in vitro</em> assay, especially after exposure to GEN. In the <em>in vivo</em> assay the highest scores were recorded in DG, especially in the presence of DIC. The distinct responses of G and DG underscore their roles in respiration and detoxification, with G being more sensitive to acute stress and DG exhibiting greater adaptive capacity over time. Furthermore, it appears that GEN caused the greatest impact on G after the <em>in vitro</em> assay, while DIC had the most significant effect on DG following the <em>in vivo</em> experiment. <em>In vitro</em> assays demonstrated limited oxidative stress and cellular damage, while <em>in vivo</em> results highlighted substantial metabolic depression and biomarker variability under prolonged exposure. When analyzed individually, the <em>in vitro</em> assay showed a clearer distinction between the two contaminants, especially in the DG. The findings underscore the differential vulnerability and adaptive capacities of G and DG, attributed to their respective roles in respiration and detoxification. These results emphasize the complementary nature of <em>in vitro</em> and <em>in vivo</em> approaches, with the former providing mechanistic insights and the latter reflecting systemic organismal responses. This study highlights the importance of a multi-dimensional approach, combining both <em>in vitro</em> and <em>in vivo</em> methodologies, to better understand tissue-specific toxicity and the broader ecological consequences of pharmaceutical contamination.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"14 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Soil enzyme activities and bacterial communities respond to co-exposure of butyl benzyl phthalate and TiO2 nanomaterials: Earthworm-mediated effects

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-03-11 DOI: 10.1016/j.envpol.2025.126049

Wanjing Liu , Xiaoqing Yang , Zhuofan Li , Yao Liu , Mengyao Yao , Mengyuan Pei , Lanlan Zhang , Cheng Zhang , Lusheng Zhu , Peng Gao , Jun Wang

Phthalic acid esters (PAEs) are widely used due to their advantageous properties, which enhance the durability, flexibility, and transparency of plastic products. Nanomaterials are also commonly used in plastic additives and agricultural fertilizers. However, both are easy to fall off, diffuse, and release into the environment during production, use, and disposal. The adsorption and transportation of PAEs by nanomaterials may jointly affect soil health. However, less attention is paid to the soil microorganisms caused by co-exposure between PAEs and nanomaterials, especially mediated by earthworms. The present study investigated the effects of BBP (1 mg kg⁻¹) and nTiO₂ (1 mg kg⁻¹), alone and in combination, on soil enzyme activities, microbial composition, and bacterial community diversity, with and without mediation by the earthworm Metaphire guillelmi. Results showed that co-exposure to BBP and nTiO₂ activated enzyme activities in earthworm-mediated soil. Both contaminants, individually and combined, altered the composition, distribution, diversity, and complexity of the soil bacterial community mediated by earthworms. Bacteroidetes, Proteobacteria, and Actinobacteria were the dominant phyla. However, the complexity of soil bacterial community networks decreased. The findings highlight the importance of considering co-exposure and soil fauna mediation when evaluating the ecological impacts of emerging contaminants and fill the lack of ecotoxicity data on the co-exposure of PAEs and nanomaterials, thus promoting the design and synthesis of safer and more efficient nanomaterials.

{"title":"Soil enzyme activities and bacterial communities respond to co-exposure of butyl benzyl phthalate and TiO2 nanomaterials: Earthworm-mediated effects","authors":"Wanjing Liu , Xiaoqing Yang , Zhuofan Li , Yao Liu , Mengyao Yao , Mengyuan Pei , Lanlan Zhang , Cheng Zhang , Lusheng Zhu , Peng Gao , Jun Wang","doi":"10.1016/j.envpol.2025.126049","DOIUrl":"10.1016/j.envpol.2025.126049","url":null,"abstract":"<div><div>Phthalic acid esters (PAEs) are widely used due to their advantageous properties, which enhance the durability, flexibility, and transparency of plastic products. Nanomaterials are also commonly used in plastic additives and agricultural fertilizers. However, both are easy to fall off, diffuse, and release into the environment during production, use, and disposal. The adsorption and transportation of PAEs by nanomaterials may jointly affect soil health. However, less attention is paid to the soil microorganisms caused by co-exposure between PAEs and nanomaterials, especially mediated by earthworms. The present study investigated the effects of BBP (1 mg kg<sup>−1</sup>) and nTiO<sub>2</sub> (1 mg kg<sup>−1</sup>), alone and in combination, on soil enzyme activities, microbial composition, and bacterial community diversity, with and without mediation by the earthworm <em>Metaphire guillelmi</em>. Results showed that co-exposure to BBP and nTiO<sub>2</sub> activated enzyme activities in earthworm-mediated soil. Both contaminants, individually and combined, altered the composition, distribution, diversity, and complexity of the soil bacterial community mediated by earthworms. Bacteroidetes, Proteobacteria, and Actinobacteria were the dominant phyla. However, the complexity of soil bacterial community networks decreased. The findings highlight the importance of considering co-exposure and soil fauna mediation when evaluating the ecological impacts of emerging contaminants and fill the lack of ecotoxicity data on the co-exposure of PAEs and nanomaterials, thus promoting the design and synthesis of safer and more efficient nanomaterials.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126049"},"PeriodicalIF":7.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between short-term exposure to PM2.5 and its components and mumps incidences in Lanzhou, China

IF 8.9 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-03-11 DOI: 10.1016/j.envpol.2025.126041

Zixuan Zou, Zhenjuan Li, Donghua Li, Tingrong Wang, Rui Li, Tianshan Shi, Xiaowei Ren

To date, a limited number of studies have assessed the impact of individual and combined PM_2.5 components on mumps incidence. Between 2013 and 2019, we collected data on 6,270 mumps cases in Lanzhou, along with corresponding PM_2.5 and its components, to analyze their temporal and spatial distributions. A generalized additive mixture model was constructed to examine the association between PM_2.5 components and mumps incidence. Additionally, Bayesian kernel machine regression was used to evaluate the combined and interactive effects of co-exposure to PM_2.5 components on mumps incidence and to identify key contributing components. A significant linear correlation was found between PM_2.5 and mumps incidence at lag 1 month, with a relative risk (RR) of 1.85 (95% CI: 1.14, 3.02) for each unit increase in PM_2.5 (ln (PM_2.5) = 1 μg/m³). Organic matter (OM) at lag 0 and 1 month, as well as black carbon (BC) at lag 1 month, were significantly positively correlated with mumps incidence. Furthermore, the joint exposure-effect curve for PM_2.5 components and mumps incidence displayed an approximate V-shape. The effects of PM_2.5 and its components on mumps incidence were more pronounced during the warm season. These findings suggest a significant association between short-term exposure to PM_2.5 and its components and mumps incidence in Lanzhou, with potential variations in effect depending on the specific components of PM_2.5.

{"title":"Association between short-term exposure to PM2.5 and its components and mumps incidences in Lanzhou, China","authors":"Zixuan Zou, Zhenjuan Li, Donghua Li, Tingrong Wang, Rui Li, Tianshan Shi, Xiaowei Ren","doi":"10.1016/j.envpol.2025.126041","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.126041","url":null,"abstract":"To date, a limited number of studies have assessed the impact of individual and combined PM<sub>2.5</sub> components on mumps incidence. Between 2013 and 2019, we collected data on 6,270 mumps cases in Lanzhou, along with corresponding PM<sub>2.5</sub> and its components, to analyze their temporal and spatial distributions. A generalized additive mixture model was constructed to examine the association between PM<sub>2.5</sub> components and mumps incidence. Additionally, Bayesian kernel machine regression was used to evaluate the combined and interactive effects of co-exposure to PM<sub>2.5</sub> components on mumps incidence and to identify key contributing components. A significant linear correlation was found between PM<sub>2.5</sub> and mumps incidence at lag 1 month, with a relative risk (RR) of 1.85 (95% CI: 1.14, 3.02) for each unit increase in PM<sub>2.5</sub> (ln (PM<sub>2.5</sub>) = 1 μg/m<sup>3</sup>). Organic matter (OM) at lag 0 and 1 month, as well as black carbon (BC) at lag 1 month, were significantly positively correlated with mumps incidence. Furthermore, the joint exposure-effect curve for PM<sub>2.5</sub> components and mumps incidence displayed an approximate V-shape. The effects of PM<sub>2.5</sub> and its components on mumps incidence were more pronounced during the warm season. These findings suggest a significant association between short-term exposure to PM<sub>2.5</sub> and its components and mumps incidence in Lanzhou, with potential variations in effect depending on the specific components of PM<sub>2.5</sub>.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"195 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complex metal interaction networks and the mediating role of biological aging in dyslipidemia

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-03-11 DOI: 10.1016/j.envpol.2025.126047

Guohuan Yin , Xingyu Chen , Meiduo Zhao , Jing Xu , Qun Xu

Metal mixture exposure is a major risk factor for dyslipidemia. Numerous studies have shown an association between metal mixture exposure, biological aging, and dyslipidemia. However, the interactions between metals, their directions, and the potential mechanisms through which they influence dyslipidemia remain unclear. This study utilized data from a repeated-measures cohort collected between 2016 and 2021, including 403 participants (1612 observations). Levels of metals, including chromium (Cr), cadmium (Cd), lead (Pb), and manganese (Mn), were measured in urine, along with four dyslipidemia biomarkers and their extended indicators. Generalized Estimating Equations (GEE) and Bayesian Kernel Machine Regression (BKMR) were used to analyze the effects of single and combined metal exposures on dyslipidemia. BKMR and the Synergy Index were employed to explore binary metal interactions and their directions. Marginal effects analysis assessed the impact of multiple metal interactions on dyslipidemia, and mediation analysis was conducted to explore the role of KDM.Accel in mediating the relationship between metal exposure and dyslipidemia. The findings indicated that both individual and combined exposures to Cr, Cd, Pb, and Mn significantly affected dyslipidemia. Multiple binary metal interactions exhibited synergistic effects on lipid outcomes. Pb∗Cd∗Cr and Pb∗Cd∗Mn showed an antagonistic effect on non-high-density lipoprotein cholesterol (NHC), while Cd∗Cr∗Mn∗Pb demonstrated synergistic effects on NHC. Additionally, KDM.Accel was identified as a key mediator in the relationship between Pb exposure and dyslipidemia, influencing the associations between Pb and HDL-C, LDL-C, and AC abnormalities. Mixed heavy metal exposure and their interactions are associated with dyslipidemia outcomes, with KDM.Accel playing a mediating role in the relationship between metals and dyslipidemia. This study highlights the potential interactions between metals and the mechanisms by which KDM.Accel may influence dyslipidemia, offering new insights into the connection between metal mixtures and dyslipidemia.

{"title":"Complex metal interaction networks and the mediating role of biological aging in dyslipidemia","authors":"Guohuan Yin , Xingyu Chen , Meiduo Zhao , Jing Xu , Qun Xu","doi":"10.1016/j.envpol.2025.126047","DOIUrl":"10.1016/j.envpol.2025.126047","url":null,"abstract":"<div><div>Metal mixture exposure is a major risk factor for dyslipidemia. Numerous studies have shown an association between metal mixture exposure, biological aging, and dyslipidemia. However, the interactions between metals, their directions, and the potential mechanisms through which they influence dyslipidemia remain unclear. This study utilized data from a repeated-measures cohort collected between 2016 and 2021, including 403 participants (1612 observations). Levels of metals, including chromium (Cr), cadmium (Cd), lead (Pb), and manganese (Mn), were measured in urine, along with four dyslipidemia biomarkers and their extended indicators. Generalized Estimating Equations (GEE) and Bayesian Kernel Machine Regression (BKMR) were used to analyze the effects of single and combined metal exposures on dyslipidemia. BKMR and the Synergy Index were employed to explore binary metal interactions and their directions. Marginal effects analysis assessed the impact of multiple metal interactions on dyslipidemia, and mediation analysis was conducted to explore the role of KDM.Accel in mediating the relationship between metal exposure and dyslipidemia. The findings indicated that both individual and combined exposures to Cr, Cd, Pb, and Mn significantly affected dyslipidemia. Multiple binary metal interactions exhibited synergistic effects on lipid outcomes. Pb∗Cd∗Cr and Pb∗Cd∗Mn showed an antagonistic effect on non-high-density lipoprotein cholesterol (NHC), while Cd∗Cr∗Mn∗Pb demonstrated synergistic effects on NHC. Additionally, KDM.Accel was identified as a key mediator in the relationship between Pb exposure and dyslipidemia, influencing the associations between Pb and HDL-C, LDL-C, and AC abnormalities. Mixed heavy metal exposure and their interactions are associated with dyslipidemia outcomes, with KDM.Accel playing a mediating role in the relationship between metals and dyslipidemia. This study highlights the potential interactions between metals and the mechanisms by which KDM.Accel may influence dyslipidemia, offering new insights into the connection between metal mixtures and dyslipidemia.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126047"},"PeriodicalIF":7.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterizing full-phase chlorine species emissions from domestic coal combustion in China: Implications for significant impacts on air pollution and ozone-layer depletion

IF 7.6 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2025-03-11 DOI: 10.1016/j.envpol.2025.126043

Wenyi Jin, Yulong Yan, Xionghui Qiu, Lin Peng, Zhen Li, Yuying Tang

The distribution and emission characteristics of chlorine in different phases are important for evaluating the impact of chlorine chemistry on the stratospheric and tropospheric environment. This study developed a measurement method of full-phase chlorine and firstly reported full-phase chlorine emissions characteristics of domestic coal combustion. The chlorine content of bituminous coal is 252.5 μg/g, with 87 % released into the gaseous, and the concentrations of particulate chloride (pCl), hydrogen chloride (HCl), chlorine gas (Cl₂), and organic chlorides (Cl-VOCs) of 0.57 ± 0.16, 5.96 ± 1.05, 0.38 ± 0.06, and 0.03 ± 0.01 mg Cl/m³, respectively. In addition, unexpectedly high concentrations of very short-lived substances (VSLS), such as CH₃Cl, CH₂Cl₂, C₂H₅Cl, C₂H₃Cl, and C₂H₂Cl₂, and ozone-depleting substances (ODS), such as chlorofluorocarbons (CFCs) and hydrochlorofluorocarbons (HCFCs), were measured, with concentration of 270.71 ppb in total. Total emission of chlorine from domestic coal combustion was 33.51 tons in 2013 and declines to 18.47 tons in 2021 in China. Our results indicate that the emissions of CFC-11-eq and CO₂-eq were relatively low compared with those of other species controlled by the Montreal Protocol on Substances that Deplete the Ozone Layer; however, subsequent controls should give greater consideration to coal combustion because of its widespread sources.

{"title":"Characterizing full-phase chlorine species emissions from domestic coal combustion in China: Implications for significant impacts on air pollution and ozone-layer depletion","authors":"Wenyi Jin, Yulong Yan, Xionghui Qiu, Lin Peng, Zhen Li, Yuying Tang","doi":"10.1016/j.envpol.2025.126043","DOIUrl":"10.1016/j.envpol.2025.126043","url":null,"abstract":"<div><div>The distribution and emission characteristics of chlorine in different phases are important for evaluating the impact of chlorine chemistry on the stratospheric and tropospheric environment. This study developed a measurement method of full-phase chlorine and firstly reported full-phase chlorine emissions characteristics of domestic coal combustion. The chlorine content of bituminous coal is 252.5 μg/g, with 87 % released into the gaseous, and the concentrations of particulate chloride (pCl), hydrogen chloride (HCl), chlorine gas (Cl<sub>2</sub>), and organic chlorides (Cl-VOCs) of 0.57 ± 0.16, 5.96 ± 1.05, 0.38 ± 0.06, and 0.03 ± 0.01 mg Cl/m<sup>3</sup>, respectively. In addition, unexpectedly high concentrations of very short-lived substances (VSLS), such as CH<sub>3</sub>Cl, CH<sub>2</sub>Cl<sub>2</sub>, C<sub>2</sub>H<sub>5</sub>Cl, C<sub>2</sub>H<sub>3</sub>Cl, and C<sub>2</sub>H<sub>2</sub>Cl<sub>2</sub>, and ozone-depleting substances (ODS), such as chlorofluorocarbons (CFCs) and hydrochlorofluorocarbons (HCFCs), were measured, with concentration of 270.71 ppb in total. Total emission of chlorine from domestic coal combustion was 33.51 tons in 2013 and declines to 18.47 tons in 2021 in China. Our results indicate that the emissions of CFC-11-eq and CO<sub>2</sub>-eq were relatively low compared with those of other species controlled by the Montreal Protocol on Substances that Deplete the Ozone Layer; however, subsequent controls should give greater consideration to coal combustion because of its widespread sources.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"372 ","pages":"Article 126043"},"PeriodicalIF":7.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143589641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0