Environmental Pollution最新文献_第9页

Seasonal dynamics, risk prioritization, and management implications for industrial chemicals, pesticides, and PPCPs in the Yangtze River Delta 长江三角洲工业化学品、农药和ppcp的季节性动态、风险优先排序和管理意义

IF 7.3 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2026-01-24 DOI: 10.1016/j.envpol.2026.127729

Ying Peng , Luhang She , Qiang Xu , Chenyang Sun , Jinzhi Ren , Yining Zhang , Ziqiang Guan , Xiaowei Zhang

This study presents a comprehensive investigation into the occurrence, seasonal variations, and ecological risks of 484 contaminants of emerging concern (CECs) in the surface waters of the Yangtze River Delta. In winter, 209 CECs were detected, with industrial chemicals representing the most dominant category in terms of both concentration and proportion, underscoring industrial discharge as the primary source of pollution in the region. Significant seasonal shifts in contaminant composition were observed: industrial intermediates, surfactants, and antibiotics dominated in winter, whereas industrial intermediates, plasticizers, and herbicides prevailed in summer, reflecting the combined influence of climatic conditions and anthropogenic activities. Spatially, pollution hotspots varied dynamically with the seasons, concentrating in the highly industrialized Yangtze River basin during winter and shifting to the agriculturally intensive Taihu Lake basin in summer. Ecological risk assessment identified 18 high-risk substances, predominantly PPCPs and pesticides, among which the antifungal agent clotrimazole exhibited an extreme hazard quotient (HQ) exceeding 500. A core list of six compounds consistently posed high risks across both seasons. The risk evaluation further revealed pronounced species-specific sensitivity, with Daphnia magna being the most vulnerable, as well as notable seasonal variability, indicating that single-season assessments may underestimate the annual ecological risk. These findings provide a scientific basis for developing targeted region-, risk-, and season-specific management strategies for CECs in the Yangtze River Delta.

本文对长江三角洲表层水体中484种新兴关注污染物的发生、季节变化及生态风险进行了全面调查。在冬季，共检测到209种CECs，其中工业化学品在浓度和比例上都是最主要的类别，突出表明工业排放是该区域的主要污染源。在污染物组成上观察到显著的季节变化：工业中间体、表面活性剂和抗生素在冬季占主导地位，而工业中间体、增塑剂和除草剂在夏季占主导地位，反映了气候条件和人为活动的综合影响。空间上，污染热点随季节动态变化，冬季集中在工业化程度较高的长江流域，夏季向农业密集型的太湖流域转移。生态风险评价确定了18种高危物质，以PPCPs和农药为主，其中抗真菌剂克霉唑的极端危害商（HQ）超过500。六种化合物的核心清单在两个季节都具有很高的风险。风险评价结果显示，大水蚤（Daphnia magna）最为脆弱，且存在明显的季节差异，表明单季节评价可能低估了年生态风险。研究结果可为长三角地区CECs制定针对性区域、风险和季节管理策略提供科学依据。

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引用次数: 0

TRPA1 mediates ozone-induced murine model of COPD through the Wnt5a/GSK-3β/β-catenin pathway TRPA1通过Wnt5a/GSK-3β/β-catenin通路介导臭氧诱导小鼠COPD模型

IF 7.3 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2026-01-24 DOI: 10.1016/j.envpol.2026.127717

Meiqin Xie , Qing Chang , Chenfei Li , Qi Liu , Jiali Weng , Yi Feng , Hai Zhang , Mengnan Li , Kian Fan Chung , Ian M. Adcock , Xiaoyun Fan , Feng Li

Ambient ozone (O₃), a ubiquitous oxidant gas and key component of photochemical smog, damages the airway epithelium, provokes oxidative stress, and sustains chronic inflammation, which favors the onset and advancement of chronic obstructive pulmonary disease (COPD). Yet the molecular sensors linking long-term ozone exposure to COPD remain incompletely defined. We examined whether the oxidant-sensitive channel Transient receptor potential ankyrin 1 (TRPA1) mediates ozone-driven murine model of COPD through the Wnt5a/GSK3β/β-catenin pathway. C57BL/6J or TRPA1-deficient mice underwent ozone exposure (2.5 ppm, 3 h/session) every 3 days for 2 months, following administration of either the TRPA1 antagonist A967079 or the Wnt5a/GSK3β/β-catenin inhibitor XAV-939. Similarly, BEAS-2B cells treated with A967079 or XAV-939 or TRPA1-silenced cells were subjected to ozone (1 ppm, 3 h/day) for 4 consecutive days. Oxidative stress, inflammatory responses, emphysematous changes, mitochondrial dysfunction, and airway remodeling were assessed. In addition, gene set variation analysis (GSVA) was used to quantify Reactome Wnt5a/GSK3β/β-catenin pathway activity through public COPD transcriptomic cohorts. Pharmacological inhibition or genetic deficiency of TRPA1 significantly attenuated ozone-induced lung function impairment, and ozone-triggered oxidative stress, emphysematous changes, mitochondrial dysfunction, and airway remodeling. Notably, pharmacological suppression of the Wnt5a/GSK3β/β-catenin pathway using XAV-939 produced comparable protective effects to TRPA1 blockade in both ozone-exposed murine models and BEAS-2B cells. GSVA demonstrated tissue-specific associations between TRPA1 and Wnt5a/GSK3β/β-catenin pathway in COPD patients. TRPA1 mediates crucially ozone-induced COPD through modulation of the Wnt5a/GSK-3β/β-catenin signaling. Therapeutic targeting of both TRPA1 and Wnt5a/GSK3β/β-catenin pathway may represent a promising intervention strategy for ozone-associated COPD pathogenesis. This study elucidates the mechanisms through which ambient O₃ impairs respiratory health across the general population.

环境臭氧（O3）是一种普遍存在的氧化气体，是光化学烟雾的关键成分，它损害气道上皮，引起氧化应激，并维持慢性炎症，促进慢性阻塞性肺疾病（COPD）的发生和进展。然而，将长期臭氧暴露与慢性阻塞性肺病联系起来的分子传感器仍未完全确定。我们检测了氧化敏感通道瞬时受体电位锚蛋白1 （TRPA1）是否通过Wnt5a/GSK3β/β-catenin通路介导臭氧驱动的小鼠COPD模型。C57BL/6J或TRPA1缺陷小鼠在给予TRPA1拮抗剂A967079或Wnt5a/GSK3β/β-catenin抑制剂XAV-939后，每3天暴露一次臭氧（2.5 ppm， 3小时/次），持续2个月。同样，用A967079或XAV-939或trpa1沉默细胞处理的BEAS-2B细胞连续4天暴露于臭氧（1 ppm， 3 h/天）中。评估氧化应激、炎症反应、肺气肿变化、线粒体功能障碍和气道重塑。此外，通过公共COPD转录组队列，采用基因集变异分析（GSVA）来量化Reactome Wnt5a/GSK3β/β-catenin通路活性。TRPA1的药理抑制或遗传缺陷可显著减轻臭氧诱导的肺功能损伤、臭氧引发的氧化应激、肺气肿变化、线粒体功能障碍和气道重塑。值得注意的是，在臭氧暴露小鼠模型和BEAS-2B细胞中，使用XAV-939药理抑制Wnt5a/GSK3β/β-catenin通路产生的保护作用与阻断TRPA1相当。GSVA证实了COPD患者中TRPA1与Wnt5a/GSK3β/β-catenin通路之间的组织特异性关联。TRPA1通过调节Wnt5a/GSK-3β/β-catenin信号通路介导臭氧诱导的COPD。TRPA1和Wnt5a/GSK3β/β-catenin通路的治疗靶向可能是臭氧相关COPD发病机制的一种有希望的干预策略。本研究阐明了环境臭氧损害一般人群呼吸系统健康的机制。

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引用次数: 0

Characterizing global air pollution seasonality and trends through integrated satellite and meteorological analytics 通过综合卫星和气象分析表征全球空气污染的季节性和趋势

IF 7.3 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2026-01-23 DOI: 10.1016/j.envpol.2026.127728

Muhammad Naveed , Zulqarnain Satti , Muhammad Mateen Tahir , Qazi Muhammad Yasir , Hui Li , Faming Wang

Air pollution remains a major global health and climate challenge, contributing to 6.7–8 million premature deaths annually. Using six years (2019–2024) of monthly Sentinel-5P (NO ₂, SO ₂, CO, O ₃, and HCHO) and ERA5-Land meteorological data, this study quantified the seasonal variability, spatial regimes, and temporal evolution of global atmospheric composition. Strong and statistically significant seasonality was confirmed (ANOVA p < 0.001), with NO₂ increasing by up to 40 % in winter over South and East Asia and O₃ increasing by 35 % in summer across the mid-latitudes. Seasonal Mann-Kendall trends revealed significant global increases in NO₂ (τ = 0.50), HCHO (τ = 0.71), O₃ (τ = 0.59), and temperature, while CO and SO₂ displayed regionally mixed responses. Temperature was strongly correlated with O₃ (r = 0.52) and NO₂ (r = 0.68), whereas precipitation, humidity, and wind predominantly suppressed the accumulation of primary pollutants, highlighting the dominant influence of climate forcing. Biomass-burning regions in Africa and South America exhibited CO peaks exceeding two-fold background levels, whereas emission controls contributed to regional SO₂ and NO₂ reductions elsewhere. In particular, statistically significant declines in NO₂ and SO₂ across Europe and parts of East Asia are consistent with the effectiveness of emission control policies targeting the power generation, industrial activity, and transportation sectors. Despite providing globally consistent coverage, TROPOMI retrieval uncertainties and the absence of universal in situ validation introduce residual observational uncertainty. These insights into pollutant seasonality and short-term directional trends provide actionable information for air quality management, enabling improved seasonal forecasting, early warning assessments, and more targeted mitigation strategies at regional to global scales.

空气污染仍然是全球健康和气候的一大挑战，每年导致670万至80万人过早死亡。利用6年（2019-2024）Sentinel-5P （no2、so2、CO、o3和HCHO）和era5陆地气象资料，量化了全球大气成分的季节变化、空间格局和时间演变。在南亚和东亚地区，冬季NO2增加了40%，夏季O3增加了35%，证实了强烈且具有统计学意义的季节性（方差分析p <； 0.001）。季节Mann-Kendall趋势显示全球NO2 （τ = 0.50）、HCHO （τ = 0.71）、O3 （τ = 0.59）和温度显著增加，而CO和SO2呈现区域混合响应。温度与O3 （r = 0.52）和NO2 （r = 0.68）密切相关，而降水、湿度和风主要抑制初级污染物的积累，突出了气候强迫的主导影响。非洲和南美洲生物质燃烧地区的CO峰值超过背景水平的两倍，而其他地区的排放控制有助于区域SO2和NO2的减少。特别是，欧洲和东亚部分地区NO2和SO2在统计上显著下降，这与针对发电、工业活动和运输部门的排放控制政策的有效性是一致的。尽管提供了全球一致的覆盖范围，TROPOMI检索的不确定性和缺乏普遍的原位验证引入了剩余的观测不确定性。这些关于污染物季节性和短期定向趋势的见解为空气质量管理提供了可操作的信息，有助于改进季节性预报、早期预警评估，并在区域到全球范围内制定更有针对性的缓解战略。

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引用次数: 0

Brain concentrations of flame retardants and trace elements related to habitat use and brain measures in an urban-adapted gull 城市适应海鸥的阻燃剂和微量元素脑浓度与栖息地使用和脑测量有关。

IF 7.3 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2026-01-23 DOI: 10.1016/j.envpol.2026.127726

Anna Lippold , Mélanie F. Guigueno , Marilou Lalumière , Chavy Dworkind , Alison Aube , Amy Smith-Dijak , Brenda Toscano-Marquez , Anna A. Cook , Alanna J. Watt , Jonathan Verreault

Exposure to environmental contaminants, such as halogenated flame retardants (HFRs) and trace elements, has been associated with a several health effects, including neurotoxicity. However, information on contaminant concentrations in brain tissue and factors influencing their accumulation and exposure-related effects are limited in wild birds. We quantified 45 HFRs and 16 trace elements in brain of ring-billed gulls (Larus delawarensis) breeding in a highly urbanized environment and related their concentrations to foraging habitat use and a range of coarse and fine-scale neuroanatomical measures. Ten polybrominated diphenyl ethers (PBDEs), hexabromobenzene (HBB), pentabromoethylbenzene (PBEB), and anti-dechlorane plus (anti-DP) were detected in over 80 % of brain samples, as well as cobalt, nickel, copper, selenium, silver, cadmium, lead, and mercury. For certain compounds or elements, brain concentrations correlated with foraging habitat use, for example, PBDEs and lead increased with the proportion of time gulls spent foraging in waste management facilities. Additionally, we found correlations between brain contaminant concentrations and certain brain measures. For example, the number of immature neurons in the nucleus pretectalis principalis (Pt), a region in the visual system in birds, correlated negatively with brain concentrations of PBDEs and lead. Our results showed that urban-adapted ring-billed gulls accumulate a wide range of HFRs and trace elements in brain tissue, and that some of these contaminants might be associated with variations in selected neural measures. Although the present correlative study cannot establish causality, these findings highlight potential toxicity pathways in the avian brain that warrant mechanistic investigation under controlled conditions.

接触环境污染物，如卤代阻燃剂和微量元素，与若干健康影响有关，包括神经毒性。然而，关于野生鸟类大脑中的污染物浓度以及影响其积累和接触相关影响的因素的信息有限。本研究量化了在高度城市化环境中繁殖的环嘴鸥（Larus delawarensis）脑中的45种HFRs和16种微量元素，并将其浓度与觅食栖息地的利用和一系列粗、精细神经解剖学测量相关联。在超过80%的脑样本中检测到十种多溴二苯醚（PBDEs）、六溴苯（HBB）、五溴乙苯（PBEB）和反二氯烷（anti-DP），以及钴、镍、铜、硒、银、镉、铅和汞。对于某些化合物或元素，大脑浓度与觅食栖息地的使用有关，例如，多溴二苯醚和铅随着海鸥在废物管理设施中觅食的时间比例的增加而增加。此外，我们还发现了脑污染物浓度与某些脑测量指标之间的相关性。例如，鸟的视觉系统区域——主前核（Pt）中未成熟神经元的数量与脑内多溴二苯醚和铅的浓度呈负相关。我们的研究结果表明，适应城市的环嘴鸥在大脑中积累了广泛的HFRs和微量元素，其中一些污染物可能与选择的神经测量的变化有关。虽然目前的相关研究不能确定因果关系，但这些发现强调了鸟类大脑中潜在的毒性途径，需要在受控条件下进行机制研究。

{"title":"Brain concentrations of flame retardants and trace elements related to habitat use and brain measures in an urban-adapted gull","authors":"Anna Lippold , Mélanie F. Guigueno , Marilou Lalumière , Chavy Dworkind , Alison Aube , Amy Smith-Dijak , Brenda Toscano-Marquez , Anna A. Cook , Alanna J. Watt , Jonathan Verreault","doi":"10.1016/j.envpol.2026.127726","DOIUrl":"10.1016/j.envpol.2026.127726","url":null,"abstract":"<div><div>Exposure to environmental contaminants, such as halogenated flame retardants (HFRs) and trace elements, has been associated with a several health effects, including neurotoxicity. However, information on contaminant concentrations in brain tissue and factors influencing their accumulation and exposure-related effects are limited in wild birds. We quantified 45 HFRs and 16 trace elements in brain of ring-billed gulls (<em>Larus delawarensis</em>) breeding in a highly urbanized environment and related their concentrations to foraging habitat use and a range of coarse and fine-scale neuroanatomical measures. Ten polybrominated diphenyl ethers (PBDEs), hexabromobenzene (HBB), pentabromoethylbenzene (PBEB), and <em>anti</em>-dechlorane plus (<em>anti</em>-DP) were detected in over 80 % of brain samples, as well as cobalt, nickel, copper, selenium, silver, cadmium, lead, and mercury. For certain compounds or elements, brain concentrations correlated with foraging habitat use, for example, PBDEs and lead increased with the proportion of time gulls spent foraging in waste management facilities. Additionally, we found correlations between brain contaminant concentrations and certain brain measures. For example, the number of immature neurons in the nucleus pretectalis principalis (Pt), a region in the visual system in birds, correlated negatively with brain concentrations of PBDEs and lead. Our results showed that urban-adapted ring-billed gulls accumulate a wide range of HFRs and trace elements in brain tissue, and that some of these contaminants might be associated with variations in selected neural measures. Although the present correlative study cannot establish causality, these findings highlight potential toxicity pathways in the avian brain that warrant mechanistic investigation under controlled conditions.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"394 ","pages":"Article 127726"},"PeriodicalIF":7.3,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146045946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined cellular (Cells-on-Particles) and acellular (DTT) assessment of indoor vs outdoor PM2.5 toxicity 室内和室外PM2.5毒性的联合细胞（细胞对颗粒）和非细胞（DTT）评估

IF 7.3 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2026-01-23 DOI: 10.1016/j.envpol.2026.127727

Gaile Poceviciute , Violeta Kauneliene , Edvardas Bagdonas , Darius Ciuzas , Martynas Tichonovas , Jurgita Ovadnevaite , Monika Eimutyte , Dainius Martuzevicius

Air pollution is a complex mixture of particles and gases, and its characterization by physical and chemical methods may not fully capture health-relevant effects. Assessing how pollutants interact with living cells provides complementary insight into their potential harmful effects. An integrated “Cells-on-Particles” platform was employed to assess the cytotoxicity of indoor and outdoor PM_2.5 using human bronchial epithelial BEAS-2B cells. In this model, cells are directly cultured on collected aerosol particles, enabling an assessment of particle-induced cellular responses. The biological assay was complemented by an acellular dithiothreitol (DTT) assay, which quantifies the oxidative activity of particles and provides insight into their redox activity. Both indoor and outdoor PM_2.5 induced dose-dependent cytotoxicity, with outdoor particles showing stronger effects and higher DTT activity. A strong inverse linear association between DTT activity and cell viability was observed (for indoor R² = 0.96; for outdoor R² = 0.99), consistent with oxidative activity contributing to the observed cellular effects within this dataset. Under the indoor sampling conditions and PM_2.5 size-selective collection, indoor PM_2.5 was consistent with predominantly infiltrated outdoor fine particles. The indoor-outdoor differences may reflect infiltration and indoor residence processes. These results demonstrate that integrating the “Cells-on-Particles” exposure model with the DTT assay provides an integrated, a deposition-relevant approach for evaluating the toxicological impact of complex aerosol mixtures.

空气污染是颗粒和气体的复杂混合物，用物理和化学方法对其进行表征可能无法完全捕捉到与健康有关的影响。评估污染物如何与活细胞相互作用提供了对其潜在有害影响的补充见解。采用“细胞对颗粒”集成平台，利用人支气管上皮BEAS-2B细胞评估室内和室外PM2.5的细胞毒性。在这个模型中，细胞直接在收集的气溶胶颗粒上培养，从而能够评估颗粒诱导的细胞反应。生物实验由非细胞二硫苏糖醇（DTT）实验补充，该实验量化了颗粒的氧化活性，并提供了对其氧化还原活性的见解。室内和室外PM2.5均引起剂量依赖性细胞毒性，室外PM2.5的作用更强，DTT活性更高。观察到DTT活性与细胞活力之间存在强烈的线性反比关系（室内R2 =0.96；室外R2 = 0.99），这与氧化活性有助于本数据集中观察到的细胞效应一致。在室内采样条件和PM2.5粒径选择性采集条件下，室内PM2.5与室外细颗粒物为主的浸润性一致。室内外差异可能反映了渗透和室内居住过程。这些结果表明，将“细胞对颗粒”暴露模型与DTT分析相结合，为评估复杂气溶胶混合物的毒理学影响提供了一种综合的、与沉积相关的方法。

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引用次数: 0

Mechanistic insights into ozone-induced reduction in antibiotic resistance gene abundance in PM2.5 臭氧诱导PM2.5中抗生素抗性基因丰度减少的机制见解

IF 7.3 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2026-01-23 DOI: 10.1016/j.envpol.2026.127725

Tong Li, Jiajia Wu, Zhenglong Kuai, Mulan Cui, Tingting Du, Lijun Wu

Antibiotic resistance genes (ARGs) in PM_2.5 have received great attention due to their potential risks to human health and ecological balance. The distribution and abundance of ARGs are known to be influenced by various environmental factors. However, the effect of ozone—a major atmospheric pollutant—on the abundance of ARGs in PM_2.5 remains poorly understood. In this study, we show that as ozone pollution levels increase, the abundance of eight typical ARGs in PM_2.5 collected from four monitoring sites across three representative cities in China's Jianghuai region generally decreases. Notably, tetW, sul1, and blaTEM genes exhibit the most substantial reduction in abundance, demonstrating the highest sensitivity to ozone. Ozone affects the abundance of these three ARGs through both vertical and horizontal gene transfer, but with differing mechanisms. For vertical gene transfer, ozone reduces the abundance of these sensitive ARGs by inhibiting potential bacterial hosts. The identity of these potential hosts varies depending on the type of ARG and the sampling location. For horizontal gene transfer, ozone diminishes the abundance of tetW and blaTEM genes by reducing the abundance of mobile genetic elements. In contrast, the guanine-rich and ozone-responsive sul1 gene is primarily decreased through ozone-driven efficient degradation of extracellular sul1. These findings advance our understanding on the interactions between atmospheric pollutants and antibiotic resistance, providing a theoretical foundation for accurately assessing their human exposure risks.

PM2.5中的抗生素耐药基因（Antibiotic resistance genes, ARGs）因其对人类健康和生态平衡的潜在风险而备受关注。已知ARGs的分布和丰度受各种环境因素的影响。然而，臭氧（一种主要的大气污染物）对PM2.5中ARGs含量的影响仍然知之甚少。在本研究中，我们发现随着臭氧污染水平的增加，从中国江淮地区三个代表性城市的四个监测点收集的PM2.5中8种典型ARGs的丰度普遍下降。值得注意的是，tetW、sul1和blaTEM基因的丰度减少幅度最大，对臭氧的敏感性最高。臭氧通过垂直和水平的基因转移影响这三种ARGs的丰度，但作用机制不同。对于垂直基因转移，臭氧通过抑制潜在的细菌宿主来减少这些敏感的ARGs的丰度。这些潜在宿主的身份因ARG的类型和采样地点而异。对于水平基因转移，臭氧通过降低可移动遗传元件的丰度来降低tetW和blaTEM基因的丰度。相比之下，富含鸟嘌呤和臭氧响应的sul1基因主要通过臭氧驱动的胞外sul1的有效降解而减少。这些发现促进了我们对大气污染物与抗生素耐药性之间相互作用的理解，为准确评估其人类暴露风险提供了理论基础。

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引用次数: 0

Seasonal dynamics of multiple pollutants across a spectrum of aquatic environments: Insights from long-term diffusive gradients in thin-films (DGT) technique field monitoring 水生环境中多种污染物的季节性动态：来自薄膜（DGT）技术现场监测的长期扩散梯度的见解

IF 7.3 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2026-01-23 DOI: 10.1016/j.envpol.2026.127721

Zhou Fang , Xuan Hu , Yaqin Yu , Qiulai Yin , Qiu Qin

Diffusive Gradients in Thin-films (DGT) can be used as an effective supplement of the water pollutant monitoring. However, long-term application and verification of the DGT technique in nature waters have been limited due to the substantial effort required to compare DGT results with those obtained from grab sampling. This study compared the concentrations of a variety of trace elements and emerging organic contaminants (EOCs) measured using DGT and grab sampling method during long-term in field. The results show that the precision and accuracy of DGT can meet the technical requirements. The concentrations of selected trace elements, EOCs and phosphorus were determined in freshwater systems (six rivers and two lakes) across various cities and seawater systems (two sampling sites in Yancheng) during different seasons. The sources and seasonal variations of these pollutants were analyzed. The results show the concentrations of trace elements in the surface water of Nanjing and Yancheng were in the ranges of 0.010–8.97 and 0.010–47.1 μg L⁻¹, respectively. While the EOCs in the surface water of Nanjing and Yancheng changed within the range of 0.111–390 and 0.110–207 ng L⁻¹, respectively. Surface waters in Yancheng expressed lower EOC pollutant concentrations than the surface waters in Nanjing (except for PFOA, PFOS and OPFRs). During summer and autumn, the pollutant concentrations were lower than that during spring and winter (except for pesticides). Concentrations of NH₄-N, NO₃-N, and phosphorus were also measured via grab sampling and DGT for water quality assessment. The Predicted No-Effect Concentrations (PNECs) of the target trace elements and EOCs were calculated to evaluate the environmental risks of these substances on aquatic species. The levels of most target detected in this work did not appear to present risks to the aquatic species. However, a few substances showed moderate or high risk.

薄膜扩散梯度（DGT）可以作为水污染物监测的有效补充。然而，DGT技术在自然水域的长期应用和验证受到限制，因为将DGT结果与抓取采样结果进行比较需要付出大量的努力。本研究比较了采用DGT法和抓斗法长期田间测量的多种微量元素和新兴有机污染物（EOCs）的浓度。结果表明，DGT的精度和精度满足技术要求。测定了不同季节不同城市淡水系统（6条河流和2个湖泊）和海水系统（盐城2个采样点）中选定微量元素、EOCs和磷的浓度。分析了这些污染物的来源和季节变化。结果表明：南京和盐城地表水中微量元素含量分别在0.010 ~ 8.97和0.010 ~ 47.1 μ L−1之间；南京和盐城地表水EOCs变化范围分别为0.111 ~ 390和0.110 ~ 207 ng L−1。盐城地表水EOC污染物浓度低于南京市地表水（PFOA、PFOS和OPFRs除外）。夏季和秋季污染物浓度均低于春季和冬季（除农药外）。通过抓取采样和DGT法测定了NH4-N、NO3-N和磷的浓度，用于水质评价。通过计算目标微量元素和EOCs的预测无效应浓度（PNECs）来评价这些物质对水生物种的环境风险。在这项工作中检测到的大多数目标水平似乎不会对水生物种造成危险。然而，少数物质显示出中度或高风险。

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引用次数: 0

Occurrence, patterns and previously overlooked sources of three veterinary ectoparasiticides in rural and urban Welsh rivers 发生，模式和以前忽视的三种兽医体外寄生虫杀虫剂在农村和城市威尔士河流的来源。

IF 7.3 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2026-01-22 DOI: 10.1016/j.envpol.2026.127713

Molly Hadley , Laura Rodwell , Matt Stewart , Daniel Crowther , Jasper Linley-Adams , Sian Craig , Suzanne Thomas , Anthony Gravell , Isabelle Durance , Ian P. Vaughan , S.J. Ormerod

Chemicals from pet flea-treatments or sheep-dips sometimes exceed no-effect concentrations in rivers. We investigated three such compounds – imidacloprid, fipronil and diazinon – in nine Welsh rivers during 2021–2023. We analysed 140 grab samples using ultra high-performance liquid chromatography with quadrupole-time-of-flight mass spectrometry (LC/Q-TOF-MS) to assess how concentrations varied i) within and among rural and urban rivers in relation to wastewater inputs; ii) with an indicator of wastewater contamination, caffeine, and iii) with flow. We assessed fish and macroinvertebrate communities along a concentration gradient in the most contaminated stream. Imidacloprid (0–76 ng/L) occurred in 77 % of samples and fipronil (0–35 ng/L) in 44 %. Odds of detection were 26X and 8X greater in urban than rural sites for imidacloprid and fipronil, respectively, exceeding predicted no-effect concentrations (PNECs) in 38 % and 44 % of urban samples. Both compounds increased downstream in urban reaches i) receiving wastewater outfalls and ii) where sewer misconnections apparently impacted invertebrate communities. Significant correlations with caffeine confirmed links with wastewater. Imidacloprid, fipronil and caffeine were modelled effectively from Wastewater Treatment (WWTP) discharge, but model residuals were consistent with additional effects from misconnected sewers. In contrast, diazinon occurred patchily linked to livestock farming in the Wye (174 ng/L), Tywi (29 ng/L) and Ely (94 ng/L). Flow effects on all concentrations were weak.

These data provide important support for the role of ‘down the drain’ routes through which compounds used as pet flea-treatments reach British rivers, for the first time revealing that misconnected sewers might increase imidacloprid concentrations sufficient for observable biological effects.

宠物跳蚤治疗或羊浸液中产生的化学物质有时在河流中的浓度超过无效果浓度。我们在2021-2023年期间在威尔士的九条河流中调查了三种这样的化合物——吡虫啉、氟虫腈和二嗪农。我们使用超高效液相色谱和四极杆飞行时间质谱（LC/Q-TOF-MS）分析了140个抓样，以评估农村和城市河流内部和之间与废水输入有关的浓度变化；Ii)带有废水污染指标，咖啡因和iii)带有流量。我们在污染最严重的河流中沿浓度梯度评估了鱼类和大型无脊椎动物群落。77%的样本中含有吡虫啉（0 ~ 76 ng/L）， 44%的样本中含有氟虫腈（0 ~ 35 ng/L）。吡虫啉和氟虫腈在城市的检出率分别比农村地区高26倍和8倍，在38%和44%的城市样本中超过了预测的无效应浓度（pnec）。这两种化合物在城市下游地区都有所增加，1)接收废水排放，2)下水道连接不当明显影响无脊椎动物群落。咖啡因的显著相关性证实了与废水的联系。吡虫啉、氟虫腈和咖啡因在污水处理（WWTP）排放中得到了有效的模拟，但模型残留量与误连接下水道的影响一致。相比之下，在怀（174 ng/L）、泰威（29 ng/L）和伊利（94 ng/L）的畜牧业中，偶氮肼出现了零星的关联。流动对各浓度的影响均较弱。这些数据为“下水道通道”的作用提供了重要支持，用于治疗宠物跳蚤的化合物通过这些通道进入英国河流，首次揭示了连接不当的下水道可能会增加吡虫啉的浓度，足以产生可观察到的生物效应。

{"title":"Occurrence, patterns and previously overlooked sources of three veterinary ectoparasiticides in rural and urban Welsh rivers","authors":"Molly Hadley , Laura Rodwell , Matt Stewart , Daniel Crowther , Jasper Linley-Adams , Sian Craig , Suzanne Thomas , Anthony Gravell , Isabelle Durance , Ian P. Vaughan , S.J. Ormerod","doi":"10.1016/j.envpol.2026.127713","DOIUrl":"10.1016/j.envpol.2026.127713","url":null,"abstract":"<div><div>Chemicals from pet flea-treatments or sheep-dips sometimes exceed no-effect concentrations in rivers. We investigated three such compounds – imidacloprid, fipronil and diazinon – in nine Welsh rivers during 2021–2023. We analysed 140 grab samples using ultra high-performance liquid chromatography with quadrupole-time-of-flight mass spectrometry (LC/Q-TOF-MS) to assess how concentrations varied i) within and among rural and urban rivers in relation to wastewater inputs; ii) with an indicator of wastewater contamination, caffeine, and iii) with flow. We assessed fish and macroinvertebrate communities along a concentration gradient in the most contaminated stream. Imidacloprid (0–76 ng/L) occurred in 77 % of samples and fipronil (0–35 ng/L) in 44 %. Odds of detection were 26X and 8X greater in urban than rural sites for imidacloprid and fipronil, respectively, exceeding predicted no-effect concentrations (PNECs) in 38 % and 44 % of urban samples. Both compounds increased downstream in urban reaches i) receiving wastewater outfalls and ii) where sewer misconnections apparently impacted invertebrate communities. Significant correlations with caffeine confirmed links with wastewater. Imidacloprid, fipronil and caffeine were modelled effectively from Wastewater Treatment (WWTP) discharge, but model residuals were consistent with additional effects from misconnected sewers. In contrast, diazinon occurred patchily linked to livestock farming in the Wye (174 ng/L), Tywi (29 ng/L) and Ely (94 ng/L). Flow effects on all concentrations were weak.</div><div>These data provide important support for the role of ‘down the drain’ routes through which compounds used as pet flea-treatments reach British rivers, for the first time revealing that misconnected sewers might increase imidacloprid concentrations sufficient for observable biological effects.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"394 ","pages":"Article 127713"},"PeriodicalIF":7.3,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146043642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Longitudinal triglyceride-glucose index and Metal Interactions: A multi-model cohort integrating synergistic and antagonistic indices 纵向甘油三酯-葡萄糖指数和金属相互作用：综合协同和拮抗指标的多模型队列

IF 7.3 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2026-01-22 DOI: 10.1016/j.envpol.2026.127712

Jinhao Jia , Yihong Di , Limeng Xiong , Buyun Liu , Zeyang Bai , Jiaming Fu , Yuhan Zhang , Xiaozhe Geng , Yuxi Wang , Chunqing Gao , Guojie Qiao , Hao Hu , Rui Zhang , GuangJun Wang , Huifang Yang , Jian Sun

Longitudinal dynamics of metal exposures on insulin resistance quantified by the triglyceride-glucose (TyG) index—remain poorly characterized. We aim to explore the combined and interactive effects of metals on TyG index among Chinese elderly. This prospective cohort included 2732 Chinese elders with baseline urinary concentrations of metals quantified via ICP-MS. Analyses employed a multi-model framework beginning with linear mixed-effects models that incorporated random intercepts to assess metal-time interactions, followed by weighted quantile sum regression to evaluate metal mixture effects, and culminating in extended linear mixed models that computed the interaction effects for all pairwise metal-metal-time combinations. Single-metal analysis identified zinc (Zn), molybdenum (Mo), arsenic (As), strontium (Sr), and copper (Cu) as positively associated with the TyG index, while iron (Fe) and cadmium (Cd) were inversely associated. The positive associations for Zn, Mo, As, Sr, and Cu attenuated over time, whereas the inverse association for Fe strengthened. The Weighted Quantile Sum (WQS) model indicated an overall positive mixture effect on the TyG index, primarily driven by Zn and Mo, with Fe acting as an antagonist. Ternary interaction analysis among 78 metal pairs revealed 28 significant metal × metal × time interactions, with vanadium (V) featuring in several key antagonistic combinations. Sex-stratified analyses showed modification of these associations, and findings remained robust in sensitivity analyses. In summary, individual and mixed metal exposures are longitudinally associated with insulin resistance in the elderly, characterized by time-dependent and interactive effects, highlighting the necessity of considering complex exposure dynamics and susceptibility in risk assessment.

通过甘油三酯-葡萄糖（TyG）指数量化的金属暴露对胰岛素抵抗的纵向动力学特征仍然很差。我们的目的是探讨金属对中国老年人TyG指数的联合和交互影响。该前瞻性队列包括2732名中国老年人，通过ICP-MS量化基线尿液金属浓度。分析采用多模型框架，首先是线性混合效应模型，其中包含随机截距来评估金属-时间相互作用，然后是加权分位数和回归来评估金属混合效应，最后是扩展线性混合模型，计算所有金属-金属-时间两两组合的相互作用效应。单金属分析发现，锌（Zn）、钼（Mo）、砷（As）、锶（Sr）和铜（Cu）与TyG指数呈正相关，而铁（Fe）和镉（Cd）呈负相关。Zn、Mo、As、Sr和Cu的正相关性随着时间的推移而减弱，而Fe的负相关性则增强。加权分位数和（WQS）模型显示，TyG指数总体呈正混合效应，主要由Zn和Mo驱动，Fe作为拮抗剂。对78对金属进行三元相互作用分析，发现28种金属×金属×时间相互作用显著，其中钒(V)具有几个关键的拮抗组合。性别分层分析显示了这些关联的改变，敏感性分析的结果仍然稳健。综上所述，个体和混合金属暴露与老年人胰岛素抵抗具有纵向相关性，具有时间依赖性和相互作用的特点，强调了在风险评估中考虑复杂暴露动力学和易感性的必要性。

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引用次数: 0

Seasonal temperature rise influences nitrous oxide and methane accumulation in freshwater habitats via distinctive microbial processes 季节性气温上升通过不同的微生物过程影响淡水生境中氧化亚氮和甲烷的积累

IF 7.3 2区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environmental Pollution

Pub Date : 2026-01-22 DOI: 10.1016/j.envpol.2026.127724

Teng-Fei Ma , Wen-Ke Liu , Chong-Yang Xing , Ya-Song Chen , Hui-Min Fu , Ji-Chun Bai , Wan Sun , Meng-Meng Liu , Shun-Li Cheng , Meng-Wen Peng

Under global warming, the microbial mechanism linking seasonal temperature rise to nitrous oxide (N₂O) and methane (CH₄) dynamics in freshwater habitats remains unclear. This study sampled water/sediment from 4 habitats in fragmented rivers (Liangtan River, Chongqing, China) in winter and summer, analyzing environmental parameters, N₂O/CH₄, and microbial communities. Results showed that seasonal temperature rise (winter: 8.3–12.1 °C; summer: 27.7–36.1 °C) was associated with increased CH₄ concentrations (0.049–2.40 vs 0.054–34.06 μmol/L) and decreased N₂O concentrations (0.022–0.112 vs 0.009–0.059 μmol/L) in water. Mechanistically, seasonal temperature rise was linked to the increased total particulate matter (a key substrate for methanogens) and the reduced abundance of Methylocystis (a dominant methane oxidizer), which may contribute to CH₄ accumulation. For N₂O, seasonal warming was associated with increased the relative abundance of Steroidobacteraceae and Dechloromonas (bacteria that are capable of complete denitrification). These findings improve the understanding of the mechanisms through which seasonal temperature rise influences greenhouse gas dynamics in freshwater habitats, and provides valuable insights for fragmented river management and greenhouse gas mitigation.

在全球变暖背景下，淡水生境中季节性气温上升与氧化亚氮和甲烷动态之间的微生物机制尚不清楚。本研究在冬季和夏季对重庆梁滩河破碎化河流4个生境的水/沉积物进行采样，分析环境参数、N2O/CH4和微生物群落。结果表明：季节增温（冬季8.3 ~ 12.1℃，夏季27.7 ~ 36.1℃）与水体中CH4浓度升高（0.049 ~ 2.40 vs 0.054 ~ 34.06 μmol/L）和N2O浓度降低（0.022 ~ 0.112 vs 0.009 ~ 0.059 μmol/L）相关。从机制上说，季节性气温升高与总颗粒物（产甲烷菌的关键底物）的增加和甲烷氧化菌（主要的甲烷氧化剂）丰度的减少有关，这可能有助于CH4的积累。对于N2O，季节变暖与甾杆菌科和脱氯单胞菌（能够完全反硝化的细菌）的相对丰度增加有关。这些发现提高了对季节性温度上升影响淡水栖息地温室气体动态的机制的理解，并为碎片化河流管理和温室气体减缓提供了有价值的见解。

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引用次数: 0