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Indoor overheating: A review of vulnerabilities, causes, and strategies to prevent adverse human health outcomes during extreme heat events 室内过热:回顾极端高温事件期间的脆弱性、原因和预防不利人类健康后果的战略
Q1 Biochemistry, Genetics and Molecular Biology Pub Date : 2024-06-04 DOI: 10.1080/23328940.2024.2361223
Glen P. Kenny, Emily J. Tetzlaff, W. Journeay, Sarah B. Henderson, Fergus K O'Connor
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引用次数: 0
Thermal and cardiovascular heat adaptations in active adolescents following summer 夏季过后,好动青少年的热量和心血管热量适应情况
Q1 Biochemistry, Genetics and Molecular Biology Pub Date : 2024-05-05 DOI: 10.1080/23328940.2024.2347161
Harry A. Brown, T. Topham, Brad Clark, Andrew P Woodward, Leonidas G. Ioannou, A. Flouris, Richard D. Telford, James W. Smallcombe, Ollie Jay, Julien D. Périard
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引用次数: 0
Alpha-2-adrenergic agonists reduce resting energy expenditure in humans during external cooling α-2-肾上腺素能激动剂能减少人体在外部降温时的静息能量消耗
Q1 Biochemistry, Genetics and Molecular Biology Pub Date : 2024-04-21 DOI: 10.1080/23328940.2024.2339781
Clifton W. Callaway, Katharyn L Flickinger, Alexandra Weissman, Francis X. Guyette, Ryann DeMaio, Andrea Jonsson, Victor Wu, Jenna L. Monteleone, Peter Prescott, Jonathan Birabaharan, Daniel J. Buysse, P. Empey, Thomas D. Nolin, Raymond E. West
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引用次数: 0
Hypothalamic control of torpor and hibernation 下丘脑对休眠和冬眠的控制
Q1 Biochemistry, Genetics and Molecular Biology Pub Date : 2024-04-19 DOI: 10.1080/23328940.2024.2339794
H. Yamaguchi
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引用次数: 0
A most peculiar parasol: Exploring thermoregulation through human hair curl. 一把最奇特的阳伞:通过人的卷发探索体温调节。
Q1 Biochemistry, Genetics and Molecular Biology Pub Date : 2024-04-02 eCollection Date: 2024-01-01 DOI: 10.1080/23328940.2023.2279032
Tina Lasisi
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引用次数: 0
About the cover. 关于封面
Q1 Biochemistry, Genetics and Molecular Biology Pub Date : 2024-04-02 eCollection Date: 2024-01-01 DOI: 10.1080/23328940.2024.2329151
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引用次数: 0
Temperature gating in thermoTRPs may depend on temperature-dependent heat capacity differences thermoTRP中的温度门控可能取决于与温度相关的热容量差异
Q1 Biochemistry, Genetics and Molecular Biology Pub Date : 2024-04-02 DOI: 10.1080/23328940.2024.2321066
Frank Yeh
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引用次数: 0
Heat stress increases carbohydrate oxidation rates and oxygen uptake during prolonged load carriage exercise. 在长时间的负重运动中,热应激会增加碳水化合物的氧化率和摄氧量。
Q1 Biochemistry, Genetics and Molecular Biology Pub Date : 2024-03-09 eCollection Date: 2024-01-01 DOI: 10.1080/23328940.2024.2322920
Paul Rosbrook, Daniel Sweet, JianBo Qiao, David P Looney, Lee M Margolis, David Hostler, Riana R Pryor, J Luke Pryor

Military missions are conducted in a multitude of environments including heat and may involve walking under load following severe exertion, the metabolic demands of which may have nutritional implications for fueling and recovery planning. Ten males equipped a military pack loaded to 30% of their body mass and walked in 20°C/40% relative humidity (RH) (TEMP) or 37°C/20% RH (HOT) either continuously (CW) for 90 min at the first ventilatory threshold or mixed walking (MW) with unloaded running intervals above the second ventilatory threshold between min 35 and 55 of the 90 min bout. Pulmonary gas, thermoregulatory, and cardiovascular variables were analyzed following running intervals. Final rectal temperature (MW: p < 0.001, g = 3.81, CW: p < 0.001, g = 4.04), oxygen uptake, cardiovascular strain, and energy expenditure were higher during HOT trials (p ≤ 0.05) regardless of exercise type. Both HOT trials elicited higher final carbohydrate oxidation (CHOox) than TEMP CW at min 90 (HOT MW: p < 0.001, g = 1.45, HOT CW: p = 0.009, g = 0.67) and HOT MW CHOox exceeded TEMP MW at min 80 and 90 (p = 0.049, g = 0.60 and p = 0.024, g = 0.73, respectively). There were no within-environment differences in substrate oxidation indicating that severe exertion work cycles did not produce a carryover effect during subsequent loaded walking. The rate of CHOox during 90 minutes of load carriage in the heat appears to be primarily affected by accumulated thermal load.

军事任务是在包括高温在内的多种环境下执行的,可能需要在剧烈运动后负重行走,其新陈代谢需求可能会对燃料和恢复计划产生营养影响。十名男性装备了装载量为体重 30% 的军用背包,在 20°C/40% 相对湿度 (RH) (TEMP)或 37°C/20% 相对湿度 (HOT) 的环境中步行 90 分钟,在第一通气阈值下连续步行 (CW),或混合步行 (MW),并在 90 分钟的第 35 分钟至第 55 分钟之间进行超过第二通气阈值的无负荷跑步。在跑步间隔之后,对肺气体、体温调节和心血管变量进行分析。最终直肠温度(MW:p p p ≤ 0.05)与运动类型无关。在第 90 分钟时,热负荷试验所产生的最终碳水化合物氧化(CHOox)均高于热负荷 CW 试验(热负荷 MW:p p = 0.009,g = 0.67);在第 80 和 90 分钟时,热负荷 MW CHOox 超过热负荷 MW(分别为 p = 0.049,g = 0.60 和 p = 0.024,g = 0.73)。底物氧化在环境内没有差异,这表明在随后的负重行走过程中,严重劳累工作循环不会产生带入效应。在高温下负重行走 90 分钟期间,CHOox 的速率似乎主要受累积热负荷的影响。
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引用次数: 0
Pre-exercise hot water immersion increased circulatory heat shock proteins but did not alter muscle damage markers or endurance capacity after eccentric exercise. 运动前热水浸泡会增加循环热休克蛋白,但不会改变肌肉损伤指标或偏心运动后的耐力能力。
Q1 Biochemistry, Genetics and Molecular Biology Pub Date : 2024-03-07 eCollection Date: 2024-01-01 DOI: 10.1080/23328940.2024.2313954
Xiang Ren Tan, Ivan C C Low, Tuck Wah Soong, Jason K W Lee

Pre-exercise passive heating attenuates muscle damage caused by eccentric exercise in rats where the induction of heat shock proteins (HSPs) confers a myoprotective effect. We investigated whether pre-exercise hot water immersion (HWI) confers similar benefits in humans. Eleven recreational male athletes were immersed in 41°C water up to 60 min or until rectal temperatures reached 39.5°C. After a 6 h rest, the participants performed an eccentric downhill run for 1 h at -4% gradient to induce muscle damage. An endurance capacity test at 75% VO2max was conducted 18 h later. The control trial was similar except that participants were immersed at 34°C. Blood samples were collected to assess HSPs levels, creatine kinase, and lactate dehydrogenase activities. Plasma eHSP70 was higher post-immersion in HWI trials (1.3 ± 0.4 vs 1.1 ± 0.4; p = 0.005). Plasma eHSP27 was higher before (p = 0.049) and after (p = 0.015) endurance test in HWI. Leukocytic p-HSP27 was increased 18 h after HWI (0.97 ± 0.14 vs 0.67 ± 0.11; p = 0.04). Creatine kinase and lactate dehydrogenase activities were increased by 3-fold and 1.5-fold, respectively, after endurance test in HWI but did not differ across trials (p > 0.05). Mean heart rates were higher during eccentric run and endurance test in HWI as compared to control (p < 0.05). Endurance capacity was similar between trials (57.3 ± 11.5 min vs 55.0 ± 13.5 min; p = 0.564). Pre-exercise heating increased the expression of plasma eHSPs and leukocytic p-HSP27 but did not reduce muscle damage nor enhance endurance capacity.

运动前被动加热可减轻大鼠偏心运动造成的肌肉损伤,诱导热休克蛋白(HSPs)可产生肌保护作用。我们研究了运动前热水浸泡(HWI)是否会给人类带来类似的益处。11 名休闲男性运动员被浸泡在 41°C 的水中长达 60 分钟或直到直肠温度达到 39.5°C。休息 6 小时后,参赛者在-4%的坡度上进行了 1 小时的偏心下坡跑,以诱发肌肉损伤。18 小时后,以 75% VO2max 的速度进行耐力能力测试。对照组试验与此相似,只是参与者在 34°C 的温度下浸泡。收集血液样本以评估 HSPs 水平、肌酸激酶和乳酸脱氢酶活性。在 HWI 试验中,浸泡后血浆 eHSP70 较高(1.3 ± 0.4 vs 1.1 ± 0.4;p = 0.005)。血浆 eHSP27 在 HWI 耐力测试前(p = 0.049)和测试后(p = 0.015)都较高。HWI 18 小时后,白细胞 p-HSP27 增加(0.97 ± 0.14 vs 0.67 ± 0.11;p = 0.04)。HWI 耐力测试后,肌酸激酶和乳酸脱氢酶活性分别增加了 3 倍和 1.5 倍,但不同试验之间没有差异(p > 0.05)。与对照组相比,HWI 在偏心跑和耐力测试期间的平均心率更高(p p = 0.564)。运动前加热增加了血浆 eHSPs 和白细胞 p-HSP27 的表达,但并没有减少肌肉损伤或提高耐力能力。
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引用次数: 0
Beyond heatwaves: A nuanced view of temperature-related mortality 超越热浪:从细微处看与气温有关的死亡率
Q1 Biochemistry, Genetics and Molecular Biology Pub Date : 2024-03-04 DOI: 10.1080/23328940.2024.2310459
Abderrezak Bouchama, T. Mündel, Orlando Laitano
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引用次数: 0
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Temperature
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