Pub Date : 2020-11-17eCollection Date: 2020-01-01DOI: 10.1080/23328940.2020.1844428
{"title":"About the cover.","authors":"","doi":"10.1080/23328940.2020.1844428","DOIUrl":"https://doi.org/10.1080/23328940.2020.1844428","url":null,"abstract":"","PeriodicalId":36837,"journal":{"name":"Temperature","volume":" ","pages":"W1"},"PeriodicalIF":0.0,"publicationDate":"2020-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/23328940.2020.1844428","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38654306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-09-02eCollection Date: 2020-01-01DOI: 10.1080/23328940.2020.1801133
Anton Bespalov, Christoph Emmerich, Björn Gerlach
{"title":"Enhancing quality in preclinical data: Of hot science and cool quality.","authors":"Anton Bespalov, Christoph Emmerich, Björn Gerlach","doi":"10.1080/23328940.2020.1801133","DOIUrl":"10.1080/23328940.2020.1801133","url":null,"abstract":"","PeriodicalId":36837,"journal":{"name":"Temperature","volume":" ","pages":"301-303"},"PeriodicalIF":0.0,"publicationDate":"2020-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678921/pdf/KTMP_7_1801133.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38654303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-24eCollection Date: 2020-01-01DOI: 10.1080/23328940.2020.1768032
Antonia Kaltsatou, Sean R Notley, Glen P Kenny
Aging is associated with impairments in thermoregulatory function, which may augment the neuroendocrine and immune response in older relative to young adults during physical activity in the heat. This study was therefore aimed at examining changes in circulating endocrine hormones as cortisol (COR), prolactin (PRL), human growth hormone (hGH) and interleukin-6 (IL-6) in young and older men prior to and following an incremental, exercise-heat stress protocol (40°C and ~15% relative humidity). Accordingly, ten habitually active young (mean±SD; 21 ± 1 years) and ten older (65 ± 3 years) men performed three 30-min bouts of cycling at increasing metabolic heat productions (300, 400 and 500 W, equal to light, moderate and vigorous exercise), each separated by a 15-min recovery. Consistent with our hypothesis, we observed augmented IL-6 in older (3.55 ± 1.62 pg/mL) compared to young men (1.59 ± 0.88 pg/mL) following the protocol (p < 0.001). However, no significant between-group differences were observed for COR and hGH (all p > 0.050). We show that when assessed following incremental exercise in the heat, older men display augmented interleukin-6, but similar levels of stress hormones relative to young men.
{"title":"Effects of exercise-heat stress on circulating stress hormones and interleukin-6 in young and older men.","authors":"Antonia Kaltsatou, Sean R Notley, Glen P Kenny","doi":"10.1080/23328940.2020.1768032","DOIUrl":"https://doi.org/10.1080/23328940.2020.1768032","url":null,"abstract":"<p><p>Aging is associated with impairments in thermoregulatory function, which may augment the neuroendocrine and immune response in older relative to young adults during physical activity in the heat. This study was therefore aimed at examining changes in circulating endocrine hormones as cortisol (COR), prolactin (PRL), human growth hormone (hGH) and interleukin-6 (IL-6) in young and older men prior to and following an incremental, exercise-heat stress protocol (40°C and ~15% relative humidity). Accordingly, ten habitually active young (mean±SD; 21 ± 1 years) and ten older (65 ± 3 years) men performed three 30-min bouts of cycling at increasing metabolic heat productions (300, 400 and 500 W, equal to light, moderate and vigorous exercise), each separated by a 15-min recovery. Consistent with our hypothesis, we observed augmented IL-6 in older (3.55 ± 1.62 pg/mL) compared to young men (1.59 ± 0.88 pg/mL) following the protocol (p < 0.001). However, no significant between-group differences were observed for COR and hGH (all p > 0.050). We show that when assessed following incremental exercise in the heat, older men display augmented interleukin-6, but similar levels of stress hormones relative to young men.</p>","PeriodicalId":36837,"journal":{"name":"Temperature","volume":" ","pages":"389-393"},"PeriodicalIF":0.0,"publicationDate":"2020-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/23328940.2020.1768032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38651745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-05-18eCollection Date: 2020-01-01DOI: 10.1080/23328940.2020.1765950
Helene Volkoff, Ivar Rønnestad
As most fish are ectotherms, their physiology is strongly affected by temperature. Temperature affects their metabolic rate and thus their energy balance and behavior, including locomotor and feeding behavior. Temperature influences the ability/desire of the fish to obtain food, and how they process food through digestion, absorb nutrients within the gastrointestinal tract, and store excess energy. As fish display a large variability in habitats, feeding habits, and anatomical and physiological features, the effects of temperature are complex and species-specific. The effects of temperature depend on the timing, intensity, and duration of exposure as well as the speed at which temperature changes occur. Whereas acute short-term variations of temperature might have drastic, often detrimental, effects on fish physiology, long-term gradual variations might lead to acclimation, e.g. variations in metabolic and digestive enzyme profiles. The goal of this review is to summarize our current knowledge on the effects of temperature on energy homeostasis, with specific focus on metabolism, feeding, digestion, and how fish are often able to "adapt" to changing environments through phenotypic and physiological changes.
{"title":"Effects of temperature on feeding and digestive processes in fish.","authors":"Helene Volkoff, Ivar Rønnestad","doi":"10.1080/23328940.2020.1765950","DOIUrl":"10.1080/23328940.2020.1765950","url":null,"abstract":"<p><p>As most fish are ectotherms, their physiology is strongly affected by temperature. Temperature affects their metabolic rate and thus their energy balance and behavior, including locomotor and feeding behavior. Temperature influences the ability/desire of the fish to obtain food, and how they process food through digestion, absorb nutrients within the gastrointestinal tract, and store excess energy. As fish display a large variability in habitats, feeding habits, and anatomical and physiological features, the effects of temperature are complex and species-specific. The effects of temperature depend on the timing, intensity, and duration of exposure as well as the speed at which temperature changes occur. Whereas acute short-term variations of temperature might have drastic, often detrimental, effects on fish physiology, long-term gradual variations might lead to acclimation, <i>e.g</i>. variations in metabolic and digestive enzyme profiles. The goal of this review is to summarize our current knowledge on the effects of temperature on energy homeostasis, with specific focus on metabolism, feeding, digestion, and how fish are often able to \"adapt\" to changing environments through phenotypic and physiological changes.</p>","PeriodicalId":36837,"journal":{"name":"Temperature","volume":" ","pages":"307-320"},"PeriodicalIF":0.0,"publicationDate":"2020-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/23328940.2020.1765950","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38654305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-21eCollection Date: 2020-01-01DOI: 10.1080/23328940.2020.1741333
Christopher L Chapman, Zachary J Schlader
There has been a surge of studies published in the last 10 y examining the potential for pathology related to exercise (or physical work) in the heat and the kidneys. For instance, a PubMed search ...
{"title":"Assessing the risk of acute kidney injury following exercise in the heat: Timing is important: Comment on: Chapman, C.L., Johnson, B.D., Vargas, N.T., Hostler, D, Parker, M.D., and Schlader, Z.J. Hyperthermia and dehydration during physical work in the heat both contribute to the risk of acute kidney injury, <i>J Appl Physiol (1985)</i>, 2020. DOI: https://doi.org/10.1152/japplphysiol.00787.2019.","authors":"Christopher L Chapman, Zachary J Schlader","doi":"10.1080/23328940.2020.1741333","DOIUrl":"https://doi.org/10.1080/23328940.2020.1741333","url":null,"abstract":"There has been a surge of studies published in the last 10 y examining the potential for pathology related to exercise (or physical work) in the heat and the kidneys. For instance, a PubMed search ...","PeriodicalId":36837,"journal":{"name":"Temperature","volume":" ","pages":"304-306"},"PeriodicalIF":0.0,"publicationDate":"2020-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/23328940.2020.1741333","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38654304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-19DOI: 10.1080/23328940.2019.1664370
Ashley G B Willmott, Mark Hayes, Carl A James, Oliver R Gibson, Neil S Maxwell
Athletes exercising in heat stress experience increased perceived fatigue acutely, however it is unknown whether heat acclimation (HA) reduces the magnitude of this perceptual response and whether different HA protocols influence the response. This study investigated sensations of fatigue following; acute exercise-heat stress; short- (5-sessions) and medium-term (10-sessions) HA; and between once- (ODHA) and twice-daily HA (TDHA) protocols. Twenty male participants (peak oxygen uptake: 3.75 ± 0.47 L·min-1) completed 10 sessions (60-min cycling at ~2 W·kg-1, 45°C/20% relative humidity) of ODHA (n = 10) or non-consecutive TDHA (n = 10). Sensations of fatigue (General, Physical, Emotional, Mental, Vigor and Total Fatigue) were assessed using the multi-dimensional fatigue scale inventory-short form pre and post session 1, 5 and 10. Heat adaptation was induced following ODHA and TDHA, with reductions in resting rectal temperature and heart rate, and increased plasma volume and sweat rate (P < 0.05). General, Physical and Total Fatigue increased from pre-to-post for session 1 within both groups (P < 0.05). Increases in General, Physical and Total Fatigue were attenuated in session 5 and 10 vs. session 1 of ODHA (P < 0.05). This change only occurred at session 10 of TDHA (P < 0.05). Whilst comparative heat adaptations followed ODHA and TDHA, perceived fatigue is prolonged within TDHA.
Abbreviations: ∆: Change; ANOVA: Analysis of variance; HA: Heat acclimation; HR: Heart rate; IL-6: Interleukin-6; MFS-SF: Multi-dimensional fatigue symptom inventory-short form (MFSI-SF); MTHA: Medium-term heat acclimation; Na+: Sodium; ODHA: Once daily heat acclimation; PV: Plasma volume; RH: Relative humidity; RPE: Rating of perceived exertion; SD: Standard deviation; SE: Standard error of the slope coefficient or intercept; SEE : Standard error of the estimate for the regression equation; STHA: Short-term heat acclimation; TDHA: Twice daily heat acclimation; TC: Thermal Comfort; Tre: Rectal temperature; TSS: Thermal sensation; V̇O2peak: Peak oxygen uptake; WBSL: whole-body sweat loss.
{"title":"Heat acclimation attenuates the increased sensations of fatigue reported during acute exercise-heat stress.","authors":"Ashley G B Willmott, Mark Hayes, Carl A James, Oliver R Gibson, Neil S Maxwell","doi":"10.1080/23328940.2019.1664370","DOIUrl":"10.1080/23328940.2019.1664370","url":null,"abstract":"<p><p>Athletes exercising in heat stress experience increased perceived fatigue acutely, however it is unknown whether heat acclimation (HA) reduces the magnitude of this perceptual response and whether different HA protocols influence the response. This study investigated sensations of fatigue following; acute exercise-heat stress; short- (5-sessions) and medium-term (10-sessions) HA; and between once- (ODHA) and twice-daily HA (TDHA) protocols. Twenty male participants (peak oxygen uptake: 3.75 ± 0.47 L·min-1) completed 10 sessions (60-min cycling at ~2 W·kg-1, 45°C/20% relative humidity) of ODHA (n = 10) or non-consecutive TDHA (n = 10). Sensations of fatigue (General, Physical, Emotional, Mental, Vigor and Total Fatigue) were assessed using the multi-dimensional fatigue scale inventory-short form pre and post session 1, 5 and 10. Heat adaptation was induced following ODHA and TDHA, with reductions in resting rectal temperature and heart rate, and increased plasma volume and sweat rate (P < 0.05). General, Physical and Total Fatigue increased from pre-to-post for session 1 within both groups (P < 0.05). Increases in General, Physical and Total Fatigue were attenuated in session 5 and 10 vs. session 1 of ODHA (P < 0.05). This change only occurred at session 10 of TDHA (P < 0.05). Whilst comparative heat adaptations followed ODHA and TDHA, perceived fatigue is prolonged within TDHA.</p><p><strong>Abbreviations: </strong>∆: Change; ANOVA: Analysis of variance; HA: Heat acclimation; HR: Heart rate; IL-6: Interleukin-6; MFS-SF: Multi-dimensional fatigue symptom inventory-short form (MFSI-SF); MTHA: Medium-term heat acclimation; Na<sup>+</sup>: Sodium; ODHA: Once daily heat acclimation; PV: Plasma volume; RH: Relative humidity; RPE: Rating of perceived exertion; SD: Standard deviation; SE: Standard error of the slope coefficient or intercept; <i>SE<sub>E</sub></i> : Standard error of the estimate for the regression equation; STHA: Short-term heat acclimation; TDHA: Twice daily heat acclimation; TC: Thermal Comfort; T<sub>re</sub>: Rectal temperature; TSS: Thermal sensation; V̇O<sub>2peak</sub>: Peak oxygen uptake; WBSL: whole-body sweat loss.</p>","PeriodicalId":36837,"journal":{"name":"Temperature","volume":" ","pages":"178-190"},"PeriodicalIF":0.0,"publicationDate":"2019-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d0/56/KTMP_7_1664370.PMC7518764.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38452768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-03DOI: 10.1080/23328940.2019.1653736
Lorenz S Kissling, Ashley P Akerman, James D Cotter
ABSTRACT Tokyo 2020 will likely be the most heat stressful Olympics to date, so preparation to mitigate the effects of humid heat will be essential for performance in several of the 33 sports. One key consideration is heat acclimation (HA); the repeated exposure to heat to elicit physiological and psychophysical adaptations that improve tolerance and exercise performance in the heat. Heat can be imposed in various ways, including exercise in the heat, hot water immersion, or passive exposure to hot air (e.g., sauna). The physical requirements of each sport will determine the impact that the heat has on performance, and the adaptations required from HA to mitigate these effects. This review focuses on one key adaptation, plasma volume expansion (PVE), and how the mode of HA may affect the kinetics of adaptation. PVE constitutes a primary HA-mediated adaptation and contributes to functional adaptations (e.g., lower heart rate and increased heat loss capacity), which may be particularly important in athletes of “sub-elite” cardiorespiratory fitness (e.g., team sports), alongside athletes of prolonged endurance events. This review: i) highlights the ability of exercise in the heat, hot-water immersion, and passive hot air to expand PV, providing the first quantitative assessment of the efficacy of different heating modes; ii) discusses how this may apply to athletes at Tokyo 2020; and iii) provides recommendations regarding the protocol of HA and the prospect for achieving PVE (and the related outcomes).
{"title":"Heat-induced hypervolemia: Does the mode of acclimation matter and what are the implications for performance at Tokyo 2020?","authors":"Lorenz S Kissling, Ashley P Akerman, James D Cotter","doi":"10.1080/23328940.2019.1653736","DOIUrl":"https://doi.org/10.1080/23328940.2019.1653736","url":null,"abstract":"ABSTRACT Tokyo 2020 will likely be the most heat stressful Olympics to date, so preparation to mitigate the effects of humid heat will be essential for performance in several of the 33 sports. One key consideration is heat acclimation (HA); the repeated exposure to heat to elicit physiological and psychophysical adaptations that improve tolerance and exercise performance in the heat. Heat can be imposed in various ways, including exercise in the heat, hot water immersion, or passive exposure to hot air (e.g., sauna). The physical requirements of each sport will determine the impact that the heat has on performance, and the adaptations required from HA to mitigate these effects. This review focuses on one key adaptation, plasma volume expansion (PVE), and how the mode of HA may affect the kinetics of adaptation. PVE constitutes a primary HA-mediated adaptation and contributes to functional adaptations (e.g., lower heart rate and increased heat loss capacity), which may be particularly important in athletes of “sub-elite” cardiorespiratory fitness (e.g., team sports), alongside athletes of prolonged endurance events. This review: i) highlights the ability of exercise in the heat, hot-water immersion, and passive hot air to expand PV, providing the first quantitative assessment of the efficacy of different heating modes; ii) discusses how this may apply to athletes at Tokyo 2020; and iii) provides recommendations regarding the protocol of HA and the prospect for achieving PVE (and the related outcomes).","PeriodicalId":36837,"journal":{"name":"Temperature","volume":" ","pages":"129-148"},"PeriodicalIF":0.0,"publicationDate":"2019-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/23328940.2019.1653736","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38452765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-03DOI: 10.1080/23328940.2019.1657344
J. Wingo, Jason Ng, C. Katica, S. Carter
ABSTRACT Cardiovascular (CV) drift, the progressive increase in heart rate (HR) and decrease in stroke volume (SV) during constant rate, moderate intensity exercise, is related to reduced maximal oxygen uptake (V̇O2max) during heat stress. Once it has already occurred, it is unknown whether the detrimental effects of CV drift on V̇O2max can be reversed. This study tested the hypothesis that fan cooling after CV drift has occurred attenuates decrements in V̇O2max associated with CV drift. Eight men completed a control graded exercise test (GXT) in 22°C to measure V̇O2max. Then on separate, counterbalanced occasions, they completed one 15-min (15MIN) and two 45-min bouts (45NF and 45FAN) of cycling in 35°C, 40% RH at 60% V̇O2max, each immediately followed by a GXT to measure V̇O2max. For one of the 45-min trials (45FAN), fan airflow (4.5 m/s) was directed at participants beginning ~5 min before the GXT and continuing throughout the remainder of exercise. The purpose of the separate 15- and 45-min trials was to measure V̇O2max during the same time interval that CV drift occurred. HR increased (13.8% and 11.4%) and SV decreased (14.4% and 14.1%) for 45NF and 45FAN, respectively; trials were not different (all P > 0.05). Despite a decrease in mean skin temperature of ~1°C with fan use, V̇O2max decreased similarly between conditions (17% vs. 15% for 45NF and 45FAN, P = 0.54). Fan cooling after CV drift was insufficient to reverse the negative consequences of CV drift on V̇O2max after prolonged exercise in a hot environment. Abbreviations: 15MIN: 15-min trial; 45FAN: 45-min, fan trial; 45NF: 45-min, no fan trial; ANOVA: Analysis of variance; CV: Cardiovascular; GXT: Graded exercise test; HR: Heart rate; SV: Stroke volume; T̅b: Mean body temperature; Tre: Rectal temperature; T̅sk: Mean skin temperature; V̇O2max: Maximal oxygen uptake
{"title":"Fan cooling after cardiovascular drift does not reverse decrements in maximal oxygen uptake during heat stress","authors":"J. Wingo, Jason Ng, C. Katica, S. Carter","doi":"10.1080/23328940.2019.1657344","DOIUrl":"https://doi.org/10.1080/23328940.2019.1657344","url":null,"abstract":"ABSTRACT Cardiovascular (CV) drift, the progressive increase in heart rate (HR) and decrease in stroke volume (SV) during constant rate, moderate intensity exercise, is related to reduced maximal oxygen uptake (V̇O2max) during heat stress. Once it has already occurred, it is unknown whether the detrimental effects of CV drift on V̇O2max can be reversed. This study tested the hypothesis that fan cooling after CV drift has occurred attenuates decrements in V̇O2max associated with CV drift. Eight men completed a control graded exercise test (GXT) in 22°C to measure V̇O2max. Then on separate, counterbalanced occasions, they completed one 15-min (15MIN) and two 45-min bouts (45NF and 45FAN) of cycling in 35°C, 40% RH at 60% V̇O2max, each immediately followed by a GXT to measure V̇O2max. For one of the 45-min trials (45FAN), fan airflow (4.5 m/s) was directed at participants beginning ~5 min before the GXT and continuing throughout the remainder of exercise. The purpose of the separate 15- and 45-min trials was to measure V̇O2max during the same time interval that CV drift occurred. HR increased (13.8% and 11.4%) and SV decreased (14.4% and 14.1%) for 45NF and 45FAN, respectively; trials were not different (all P > 0.05). Despite a decrease in mean skin temperature of ~1°C with fan use, V̇O2max decreased similarly between conditions (17% vs. 15% for 45NF and 45FAN, P = 0.54). Fan cooling after CV drift was insufficient to reverse the negative consequences of CV drift on V̇O2max after prolonged exercise in a hot environment. Abbreviations: 15MIN: 15-min trial; 45FAN: 45-min, fan trial; 45NF: 45-min, no fan trial; ANOVA: Analysis of variance; CV: Cardiovascular; GXT: Graded exercise test; HR: Heart rate; SV: Stroke volume; T̅b: Mean body temperature; Tre: Rectal temperature; T̅sk: Mean skin temperature; V̇O2max: Maximal oxygen uptake","PeriodicalId":36837,"journal":{"name":"Temperature","volume":"6 1","pages":"260 - 270"},"PeriodicalIF":0.0,"publicationDate":"2019-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/23328940.2019.1657344","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49393297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-03DOI: 10.1080/23328940.2019.1665795
P. Leboit
Granuloma faciale is a diagnosis that is often overlooked clinically and by general pathologists. My experience is that clinicians often stumble into the diagnosis. There is usually only one lesion, so that their suspicion is of a neoplasm rather than of an inflammatory condition. General pathologists often do not know of the condition or remember it. This makes it a satisfying diagnosis for dermatopathologists to make. Granuloma faciale is also one of those wonderful misnomers in dermatology. The term “granuloma” reflects a clinical appearance suggesting granules, as is the case in granuloma pyogenicum and granuloma gluteale infantum, other diseases in which granulomatous inflammation does not normally occur. Lesions of granuloma faciale are seldom biopsied at an early stage. That is why the findings in an early lesion (Fig. 1, and on the cover) are worth looking at in detail. The condition is a small vessel leukocytoclastic vasculitis, but not a conventional one. There is fibrin in the walls of vessels, and neutrophils and their dust around them in both conditions. Unlike conventional leukocytoclastic vasculitis, the amount of neutrophilic nuclear dust is scant, and extravasated erythrocytes are few. The infiltrates evidently become much denser than in conventional leukocytoclastic vasculitis rather quickly. The changes that make granuloma faciale more distinctive develop with time. In addition to dense infiltrates of neutrophils, eosinophils, and plasma cells, fibrosis supervenes, often oriented concentrically around small vessels (Fig. 2). The lesions of granuloma faciale are typically solitary facial plaques (Fig. 3). They can be extraordinarily long lasting and resistant to treatment, although there have been recent reported successes with laser therapy (1). Ackerman and Mones recently briefly stated their position that granuloma faciale and erythema elevate diutinum are “different names for the same condition, namely, longstanding leukocytoclastic vasculitis on different sites, the face for the former and the extremities for the latter” (2). I believe that they are two distinct diseases. Patients with plaques of granuloma faciale on their faces may develop extrafacial granuloma faciale, but not in a symmetrical manner (3–5). Extrafacial granuloma faciale can occur without lesions on the face, although most occur with them. There is a peculiar condition, angiocentric eosinophilic fibrosis of the larynx, which can accompany granuloma faciale (6). The histopathology of extrafacial granuloma faciale (including its laryngeal variant) is similar to that of facial lesions. Erythema elevatum diutinum begins, like granuloma faciale, with neutrophils and neutrophilic nuclear dust around small vessels that have fibrin in their wall (7). The sites of predilection are different—the face is usually spared, and the skin on the dorsal aspects of joints is usually the target. The eruption is bilateral and symmetric in most cases, sometimes startlingly so (
{"title":"About the cover","authors":"P. Leboit","doi":"10.1080/23328940.2019.1665795","DOIUrl":"https://doi.org/10.1080/23328940.2019.1665795","url":null,"abstract":"Granuloma faciale is a diagnosis that is often overlooked clinically and by general pathologists. My experience is that clinicians often stumble into the diagnosis. There is usually only one lesion, so that their suspicion is of a neoplasm rather than of an inflammatory condition. General pathologists often do not know of the condition or remember it. This makes it a satisfying diagnosis for dermatopathologists to make. Granuloma faciale is also one of those wonderful misnomers in dermatology. The term “granuloma” reflects a clinical appearance suggesting granules, as is the case in granuloma pyogenicum and granuloma gluteale infantum, other diseases in which granulomatous inflammation does not normally occur. Lesions of granuloma faciale are seldom biopsied at an early stage. That is why the findings in an early lesion (Fig. 1, and on the cover) are worth looking at in detail. The condition is a small vessel leukocytoclastic vasculitis, but not a conventional one. There is fibrin in the walls of vessels, and neutrophils and their dust around them in both conditions. Unlike conventional leukocytoclastic vasculitis, the amount of neutrophilic nuclear dust is scant, and extravasated erythrocytes are few. The infiltrates evidently become much denser than in conventional leukocytoclastic vasculitis rather quickly. The changes that make granuloma faciale more distinctive develop with time. In addition to dense infiltrates of neutrophils, eosinophils, and plasma cells, fibrosis supervenes, often oriented concentrically around small vessels (Fig. 2). The lesions of granuloma faciale are typically solitary facial plaques (Fig. 3). They can be extraordinarily long lasting and resistant to treatment, although there have been recent reported successes with laser therapy (1). Ackerman and Mones recently briefly stated their position that granuloma faciale and erythema elevate diutinum are “different names for the same condition, namely, longstanding leukocytoclastic vasculitis on different sites, the face for the former and the extremities for the latter” (2). I believe that they are two distinct diseases. Patients with plaques of granuloma faciale on their faces may develop extrafacial granuloma faciale, but not in a symmetrical manner (3–5). Extrafacial granuloma faciale can occur without lesions on the face, although most occur with them. There is a peculiar condition, angiocentric eosinophilic fibrosis of the larynx, which can accompany granuloma faciale (6). The histopathology of extrafacial granuloma faciale (including its laryngeal variant) is similar to that of facial lesions. Erythema elevatum diutinum begins, like granuloma faciale, with neutrophils and neutrophilic nuclear dust around small vessels that have fibrin in their wall (7). The sites of predilection are different—the face is usually spared, and the skin on the dorsal aspects of joints is usually the target. The eruption is bilateral and symmetric in most cases, sometimes startlingly so (","PeriodicalId":36837,"journal":{"name":"Temperature","volume":"6 1","pages":"1 - 1"},"PeriodicalIF":0.0,"publicationDate":"2019-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/23328940.2019.1665795","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43027596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-06-25DOI: 10.1080/23328940.2019.1631731
Tessa Maroni, Brian Dawson, Grant Landers, Louise Naylor, Karen Wallman
The purpose of this study was to compare the separate and combined effects of two practical cooling methods (hand and torso) used prior to exercise on subsequent high-intensity cycling performance in heat. Ten trained male cyclists (V̇O2peak: 65.7 ± 10.7 ml.kg-1.min-1) performed four experimental trials (randomised within-subjects design) involving 30-min of pre-cooling (20-min seated; PRE-COOL, 10 min warm-up; PRE-COOL+WUP), while using a: (1) hand-cooling glove (CG); (2) cooling jacket (CJ); (3) both CG and CJ (CG+J); or (4) no-cooling (NC) control, followed by a cycling race simulation protocol (all performed in 35.0 ± 0.6°C and 56.6 ± 4.5% RH). During the 30-min of pre-cooling, no reductions in core (Tc) or mean skin temperature (Tsk) occurred; however, Tsk remained lower in the CJ and CG+J trials compared to NC and CG (p = 0.002-0.040, d= 0.55-1.01). Thermal sensation ratings also indicated that participants felt "hotter" during NC compared to all other trials during both PRE-COOL and PRE-COOL+WUP (p = 0.001-0.015, d= 1.0-2.19), plus the early stages of exercise (sets 1-2; p = 0.005-0.050, d= 0.56-1.22). Following cooling, no differences were found for absolute Tc and Tsk responses between trials over the entire exercise protocol (p > 0.05). Exercise and cognitive (working memory) performance also did not differ between trials (p = 0.843); however, cognitive performance improved over time in all trials (p < 0.001). In summary, pre-cooling (20-min seated and 10-min warm-up) in heat did not improve subsequent high-intensity cycling performance, cognitive responses and associated thermoregulatory strain (Tc and Tsk) compared to control.
{"title":"Hand and torso pre-cooling does not enhance subsequent high-intensity cycling or cognitive performance in heat.","authors":"Tessa Maroni, Brian Dawson, Grant Landers, Louise Naylor, Karen Wallman","doi":"10.1080/23328940.2019.1631731","DOIUrl":"10.1080/23328940.2019.1631731","url":null,"abstract":"<p><p>The purpose of this study was to compare the separate and combined effects of two practical cooling methods (hand and torso) used prior to exercise on subsequent high-intensity cycling performance in heat. Ten trained male cyclists (V̇O<sub>2</sub>peak: 65.7 ± 10.7 ml.kg<sup>-1</sup>.min<sup>-1</sup>) performed four experimental trials (randomised within-subjects design) involving 30-min of pre-cooling (20-min seated; PRE-COOL, 10 min warm-up; PRE-COOL+WUP), while using a: (1) hand-cooling glove (CG); (2) cooling jacket (CJ); (3) both CG and CJ (CG+J); or (4) no-cooling (NC) control, followed by a cycling race simulation protocol (all performed in 35.0 ± 0.6°C and 56.6 ± 4.5% RH). During the 30-min of pre-cooling, no reductions in core (Tc) or mean skin temperature (Tsk) occurred; however, Tsk remained lower in the CJ and CG+J trials compared to NC and CG (p = 0.002-0.040, <i>d</i>= 0.55-1.01). Thermal sensation ratings also indicated that participants felt \"hotter\" during NC compared to all other trials during both PRE-COOL and PRE-COOL+WUP (p = 0.001-0.015, <i>d</i>= 1.0-2.19), plus the early stages of exercise (sets 1-2; p = 0.005-0.050, <i>d</i>= 0.56-1.22). Following cooling, no differences were found for absolute Tc and Tsk responses between trials over the entire exercise protocol (p > 0.05). Exercise and cognitive (working memory) performance also did not differ between trials (p = 0.843); however, cognitive performance improved over time in all trials (p < 0.001). In summary, pre-cooling (20-min seated and 10-min warm-up) in heat did not improve subsequent high-intensity cycling performance, cognitive responses and associated thermoregulatory strain (Tc and Tsk) compared to control.</p>","PeriodicalId":36837,"journal":{"name":"Temperature","volume":" ","pages":"165-177"},"PeriodicalIF":0.0,"publicationDate":"2019-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518759/pdf/KTMP_7_1631731.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38452767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}