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BIO-SPEC: An open-source bench-top parallel bioreactor system BIO-SPEC:一个开源的台式并行生物反应器系统
IF 2.1 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-07-25 DOI: 10.1016/j.ohx.2025.e00670
Laurens Parret , Kenneth Simoens , Jo De Vrieze , Ilse Smets
The BIO-SPEC is an open-source, cost-effective, and modular bench-top bioreactor system designed for batch, sequencing batch, and chemostat cultivation. Featuring thermoelectric condensers to eliminate the need for a chiller, it ensures stable long-term operation. Controlled by a Raspberry Pi, the BIO-SPEC offers flexibility in headplate design, gas supply, and feeding strategies, making it a versatile alternative to high-cost commercial systems. This paper details the design, construction, and validation of the BIO-SPEC system, demonstrating its potential to advance microbiology and bioprocessing research through accessible and reliable hardware at a fraction of the cost of commercial systems.
BIO-SPEC是一种开源的、具有成本效益的模块化台式生物反应器系统,专为批量、测序批量和恒化培养而设计。采用热电冷凝器,消除了对冷水机的需要,确保长期稳定运行。BIO-SPEC由树莓派控制,在头板设计、气体供应和进料策略方面具有灵活性,使其成为高成本商业系统的多功能替代方案。本文详细介绍了BIO-SPEC系统的设计、构建和验证,展示了其通过可访问和可靠的硬件推进微生物学和生物处理研究的潜力,而成本只是商业系统的一小部分。
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引用次数: 0
A float-controlled self-contained laser gauge for monitoring river levels in tropical environments 一种浮子控制的自给式激光测量仪,用于监测热带环境中的河流水位
IF 2 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-07-24 DOI: 10.1016/j.ohx.2025.e00682
Alain Pierret , Norbert Silvera , Keo Oudone Latsachack , Khampasith Chanthavong , Phabvilay Sounyafong , Olivier Ribolzi
In this paper we present the design, construction and performance of a self-contained float-controlled water level gauge for monitoring water levels in streams and small rivers. This device is inexpensive (cost of about EUR 220), easy to build (no electronics skills or specialized tools required; assembled in a few hours) and straightforward to use. The gauge remains autonomously operational for several weeks in remote locations without the need for an external power supply or solar panel and in the harsh tropical climatic conditions. Data can be downloaded wirelessly in the field using an Android smartphone or tablet. This gauge is capable of a measurement precision of ±1 mm at temperatures ranging from 20 to 30 °C and accurate to within 2 mm of manual readings in a controlled laboratory environment. In the field, the mean absolute error (MAE) of measurements taken with the water level gauge compared to that obtained with the OTT-SE200 − a commercial float-controlled angle encoder water level gauge − over a full tropical rainy season and for a measurement range of 0.5 m, was 2.6 mm (n = 8,017).
本文介绍了一种用于监测溪流和小河水位的独立浮子控制水位计的设计、构造和性能。该设备价格低廉(成本约220欧元),易于构建(不需要电子技术或专门工具;组装在几个小时内)和直接使用。在偏远地区,在恶劣的热带气候条件下,该仪表可以在不需要外部电源或太阳能电池板的情况下自主运行数周。数据可以在现场用安卓智能手机或平板电脑无线下载。该仪表能够在20至30°C的温度范围内测量精度为±1毫米,并在受控的实验室环境中精确到手动读数的2毫米以内。在现场,在整个热带雨季,测量范围为0.5 m时,与商用浮子控制角度编码器水位计ot - se200相比,使用该水位计测量的平均绝对误差(MAE)为2.6 mm (n = 8,017)。
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引用次数: 0
Design, assembly, and tuning of a multipurpose FPV drone: A flexible and low-cost alternative 多用途FPV无人机的设计、组装和调试:一种灵活、低成本的选择
IF 2.1 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-07-22 DOI: 10.1016/j.ohx.2025.e00672
Franco Alessandro Arenas Mamani , Gustavo Bryam Capira Malcoaccha , Marco Antonio Blanco Quicaño , Leonardo Gabriel Prado Gutierrez , German Alberto Echaiz Espinoza , Erasmo Sulla Espinoza , Andres Ortiz Salazar
This article details the design, assembly, and tuning of a multipurpose FPV (First Person View) drone designed as a budget-friendly and customizable alternative to professional-grade drone model. Built with a focus on performance, adaptability, durability, and ease of repair, the APdrone (All Purpose Drone) incorporates high-quality components such as a carbon fiber frame, brushless motors, and advanced flight controllers. To ensure optimal flight characteristics, a comprehensive tuning process was performed using empirical adjustments, supported by controlled testing environments, to optimize PID parameters (Kp, Ki, Kd) to achieve stable and precise flight performance. Testing demonstrated a flight time of approximately 8 min under standard conditions with a maximum payload capacity of 0.98 kg. Importantly, the APdrone offers operational flexibility and significant cost savings (USD 647.09), compared to high-end drones like the DJI Mavic 3 Pro, while maintaining comparable functionality and allowing for customization. To encourage accessibility, reproducibility and further development, open-source design files, including CAD schematics, firmware configurations, and assembly instructions, are provided. The APdrone serves as a scalable platform for research, recreational use, and advancements within the UAV (Unmanned Aerial Vehicle) field.
本文详细介绍了多用途FPV(第一人称视角)无人机的设计,组装和调整,该无人机设计为预算友好且可定制的专业级无人机模型替代方案。APdrone (All Purpose Drone)专注于性能、适应性、耐用性和易于维修,采用了高质量的部件,如碳纤维框架、无刷电机和先进的飞行控制器。为了确保最优的飞行特性,在受控测试环境的支持下,利用经验调整进行了全面的整定过程,以优化PID参数(Kp, Ki, Kd),以实现稳定和精确的飞行性能。测试表明,在标准条件下飞行时间约为8分钟,最大有效载荷能力为0.98千克。重要的是,与DJI Mavic 3 Pro等高端无人机相比,APdrone提供了操作灵活性和显著的成本节约(647.09美元),同时保持了相当的功能并允许定制。为了鼓励可访问性、可重复性和进一步的开发,提供了开源设计文件,包括CAD原理图、固件配置和组装说明。APdrone作为一个可扩展的平台,用于无人机(UAV)领域的研究、娱乐和进步。
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引用次数: 0
Design and implementation of a low-cost gimbal-based angular ultrasound gantry for optimal tissue slice selection using deep learning 利用深度学习设计和实现低成本的基于云台的角度超声龙门,以实现最佳组织切片选择
IF 2 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-07-19 DOI: 10.1016/j.ohx.2025.e00676
Abhishek Kumar, Akshay S. Menon, Divyansh Sharma, Raviteja Sista, Debdoot Sheet
Ultrasound (US) is a widely popular imaging technique for the diagnosis of tumors and associated soft tissue pathology. Traditionally, excised tumor masses are manually sliced for microscopic examination, which is a resource-intensive, time-consuming process, and prone to human error. The proposed work addresses these challenges by developing a cost-effective US gantry system integrated with a deep learning algorithm to automate the tissue slice selection process. This system scans the entire tumor and by integrating a deep learning algorithm predicts the optimal slice to assist its preparation for microscopic analysis. Automating this process reduces the time and resources required while minimizing the risk of human error. Optimal tissue slice reduces sampling associated uncertainty in diagnosis and treatment planning. Thereby determining tumor grade and type, and helping to reduce the treatment risks. The initial development focused on a linear US gantry that moves in one direction to acquire B-mode images. However, this design is limited, as it cannot fully capture the tumor’s structural complexity. In order to overcome this, we developed an angular US gantry that can maneuver along multiple angles, acquiring a broader range of images for comprehensive geometric analysis. The angular gantry demonstrated significant improvement, achieving 98% accuracy in selecting the optimal tissue slice.
超声(US)是一种广泛流行的成像技术,用于诊断肿瘤和相关的软组织病理。传统上,切除的肿瘤块是人工切片进行显微镜检查,这是一个资源密集、耗时的过程,而且容易出现人为错误。提出的工作通过开发具有成本效益的美国龙门系统集成深度学习算法来自动化组织切片选择过程来解决这些挑战。该系统扫描整个肿瘤,并通过集成深度学习算法来预测最佳切片,以帮助其为显微镜分析做准备。自动化此过程可以减少所需的时间和资源,同时最大限度地减少人为错误的风险。最佳组织切片减少了诊断和治疗计划中采样相关的不确定性。从而确定肿瘤的分级和类型,并有助于降低治疗风险。最初的开发集中在一个向一个方向移动的线性美国龙门架上,以获取b模式图像。然而,这种设计是有限的,因为它不能完全捕捉肿瘤的结构复杂性。为了克服这一问题,我们开发了一种有角度的美国龙门,可以沿着多个角度进行机动,获取更广泛的图像进行全面的几何分析。角度龙门在选择最佳组织切片方面有显著的改善,准确率达到98%。
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引用次数: 0
A low-cost portable system for 3-Axis measurement of static and extremely low frequency magnetic fields 一种低成本便携式系统,用于静态和极低频磁场的三轴测量
IF 2 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-07-18 DOI: 10.1016/j.ohx.2025.e00683
Veronika Wohlmuthova, Michal Labuda, Mariana Benova
Magnetic fields play a crucial role in modern science and technology - yet precise and accessible tools for their measurement remain limited, especially for small laboratories, educators, or independent researchers. This paper introduces a novel, open-source magnetic field measurement system based on three-axis sensors for monitoring both direct and extremely low frequency magnetic fields. The device features a modular hardware design centered around a custom PCB, enabling flexible analog filtering, Bluetooth data transmission, and offline LCD visualization. By combining the MC858 and MPU9250 sensors with precise analog signal conditioning and a 12-bit ADC, the system ensures reliable detection of magnetic fields including the 50 Hz mains frequency and its harmonics. To verify the functionality of the device, experimental measurements were conducted inside a Faraday cage using a common hair dryer placed at distances of 1 cm and 3 cm from the sensors as a source of electromagnetic field. Frequency analysis confirmed reliable detection of the dominant 50 Hz component and its harmonics, as well as the system’s ability to distinguish changes in field intensity based on distance and operating state of the source device.
磁场在现代科学和技术中发挥着至关重要的作用,但是用于测量磁场的精确和可获得的工具仍然有限,特别是对于小型实验室、教育工作者或独立研究人员而言。本文介绍了一种基于三轴传感器的新型、开源的磁场测量系统,用于直接磁场和极低频磁场的监测。该器件采用模块化硬件设计,以定制PCB为中心,实现灵活的模拟滤波、蓝牙数据传输和离线LCD可视化。通过将MC858和MPU9250传感器与精确的模拟信号调理和12位ADC相结合,该系统可确保可靠地检测磁场,包括50 Hz主频率及其谐波。为了验证该装置的功能,实验测量在法拉第笼内进行,使用一个普通吹风机作为电磁场源,放置在距离传感器1厘米和3厘米的距离上。频率分析证实了对50hz分量及其谐波的可靠检测,以及系统根据源设备的距离和工作状态区分场强变化的能力。
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引用次数: 0
Low-cost electronic DC load module design for battery capacity evaluation 用于电池容量评估的低成本电子直流负载模块设计
IF 2 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-07-17 DOI: 10.1016/j.ohx.2025.e00679
Minh Nhat Huynh , Quoc Minh Lam , Cong Toai Truong , Huy Hung Nguyen , Van Tu Duong
Rapid advancements in energy storage technology spurred by the use of electricity in a variety of applications have brought attention to the critical need for precise battery capacity evaluation. The electronic DC load devices play an important role in those tests by replicating real-world discharge conditions. However, commercial DC load systems are often prohibitively expensive and remain largely inaccessible to small enterprises, academic laboratories, and independent researchers. While open-source alternatives offer cost advantages, many existing designs lack scalability, flexibility, and ease of use. This study proposes a low-cost, modular electronic DC load capable of continuous operation at up to 50W per module. With its user-friendly interface and support for numerous other tests, including constant current, constant resistor, constant power, battery evaluation, and high-power pulse charge (HPPC) the proposed electronic DC load is robust and simple to use for battery research and evaluation.
由于电力在各种应用中的使用,储能技术的快速发展引起了人们对精确电池容量评估的迫切需求的关注。电子直流负载装置在这些测试中发挥重要作用,通过复制真实的放电条件。然而,商业直流负载系统往往过于昂贵,而且小企业、学术实验室和独立研究人员在很大程度上仍然无法使用。虽然开源替代方案提供了成本优势,但许多现有设计缺乏可伸缩性、灵活性和易用性。本研究提出了一种低成本、模块化的电子直流负载,每个模块的连续工作功率高达50W。由于其用户友好的界面和支持许多其他测试,包括恒流,恒电阻,恒功率,电池评估和大功率脉冲充电(HPPC),拟议的电子直流负载是强大的,易于用于电池研究和评估。
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引用次数: 0
Fluid interaction study: Hydrodynamic robot (FISHR) — Expansion of bioinspired soft robotic fish 流体相互作用研究:流体动力机器人(FISHR)——仿生软体机器鱼的扩展
IF 2.1 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-07-16 DOI: 10.1016/j.ohx.2025.e00674
Montana Ligman, Kioumars A. Rezaie, Ramya Shah, Chris Keeter, Bryson Sutterfield, Mirjam Fürth
We introduce an enhanced iteration of OpenFish, a previously developed open-source soft robotic fish. The original model, developed at Delft University of Technology, successfully emulated thunniform swimming through a unique propulsion system utilizing both active and passive tail segments. This design aimed to optimize speed and efficiency while fostering future advancements in soft robotic fish research. To further enhance OpenFish, we undertook a redesign process, making modifications to the fish hull and internal components. These changes aimed to simplify construction, address waterproofing issues, and facilitate the development of an autonomous version of the fish. Our work encompasses an updated description of the construction process, customization options, and detailed insights into hardware implementation, including waterproofing techniques for the soft robotic fish.
我们介绍了OpenFish的增强版本,这是一个之前开发的开源软体机器鱼。最初的模型由代尔夫特理工大学开发,通过利用主动和被动尾翼的独特推进系统成功地模拟了均匀游泳。该设计旨在优化速度和效率,同时促进软性机器鱼研究的未来发展。为了进一步增强OpenFish,我们进行了重新设计,对鱼的外壳和内部组件进行了修改。这些变化旨在简化结构,解决防水问题,并促进自主版本鱼的开发。我们的工作包括对施工过程的最新描述,定制选项以及对硬件实现的详细见解,包括软机器鱼的防水技术。
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引用次数: 0
Design and construction of a small embeddable nuclear magnetic resonance sensor utilizing 3D-printed components 利用3d打印组件设计和构建小型可嵌入核磁共振传感器
IF 2 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-07-13 DOI: 10.1016/j.ohx.2025.e00678
Floriberto Díaz-Díaz , Prisciliano Felipe de Jesús Cano-Barrita
This paper presents the design and construction of a cost-effective embeddable nuclear magnetic resonance sensor using 3D printing to improve the construction process. The sensor comprises two 25.4 mm diameter x 3 mm thick neodymium-iron-boron disk magnets and an elliptical radio frequency coil. Magnetic field simulations were employed to determine the optimal separation between magnets, achieving a relatively homogeneous B0 field of 180 mT at the center of the array. Custom 3D-printed parts ensured precise magnet alignment and facilitated coil fabrication. The sensor was encased within a Faraday cage constructed from a printed circuit board to mitigate external electromagnetic interference. A remote tuning circuit was developed to tune the coil to 7.66 MHz. Initial testing involved using an eraser sample to determine the required 90° and 180° pulse amplitudes and duration. The sensor’s performance was further validated under immersion conditions in milk, yogurt, and fresh cement paste, using the Carr-Purcell-Meiboom-Gill technique. The signals obtained were processed by fitting the data to an exponential decay function to obtain the T2 lifetimes and their corresponding signal intensities, and by Inverse Laplace Transformation to obtain the T2 lifetime distribution. Results indicate the sensoŕs capability to detect variations in samples having different compositions.
本文介绍了利用3D打印技术设计和制造一种具有成本效益的嵌入式核磁共振传感器,以改进其制造工艺。该传感器由两个25.4毫米直径x 3毫米厚的钕铁硼圆盘磁铁和一个椭圆射频线圈组成。通过磁场模拟来确定磁体之间的最佳分离,在阵列中心获得了180 mT的相对均匀的B0场。定制的3d打印部件确保了精确的磁铁对准和方便的线圈制造。该传感器被封装在一个由印刷电路板构成的法拉第笼中,以减轻外部电磁干扰。开发了一种远程调谐电路,将线圈调谐到7.66 MHz。初始测试包括使用橡皮擦样品来确定所需的90°和180°脉冲幅度和持续时间。利用carr - purcell - meiboomm - gill技术,在牛奶、酸奶和新鲜水泥浆的浸泡条件下进一步验证了传感器的性能。对得到的信号进行指数衰减函数拟合,得到T2寿命及其对应的信号强度,并进行拉普拉斯逆变换,得到T2寿命分布。结果表明sensoŕs能够检测具有不同成分的样品的变化。
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引用次数: 0
PhotoNeuro: A compact photodetector for synchronization of visual stimulus presentation during behavioural experiments in neuroscience PhotoNeuro:一种用于神经科学行为实验中视觉刺激呈现同步的紧凑型光电探测器
IF 2 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-07-12 DOI: 10.1016/j.ohx.2025.e00677
Xavier Cano-Ferrer , Marcelo J. Moglie , George Konstantinou , Antonin Blot , Gaia Bianchini , Albane Imbert , Petr Znamenskiy , M. Florencia Iacaruso
Presenting visual stimuli in neuroscience experiments often requires precise temporal alignment between visual events and electrophysiological or behavioural recordings. This is typically achieved by combining analogue signals that convey timing information about the visual cue shown on liquid crystal displays (LCDs), sensed via photodetectors and recorded through analogue-to-digital converter (ADC) acquisition boards. However, most commercial photodetector systems pose limitations such as high voltage requirements, large sensor footprints that interfere with stimulus presentation, and limited compatibility with open-source platforms. Here, we present a compact, low-cost photodetector system designed for compatibility with common 3.3–5 V microcontroller-based development boards (e.g., Arduino) and the open-source visual programming language Bonsai, widely used in neuroscience for experiment control. The circuit consists of a photodiode, an amplification stage, and a low-pass filter, and can optionally incorporate an infrared filter—useful for experiments involving infrared touch displays. To facilitate reproducibility, we provide complete design files, a bill of materials and detailed building and operational instructions. We further introduce a four-channel variant, enabling the detection of four-bit binary signals for more complex synchronization needs. Validation and characterization of the device were performed through grayscale gamma correction analysis of LCD monitors using Bonsai. Additionally, we demonstrate the system’s utility in a head-fixed mouse experiment, synchronizing visual stimulus onset with neuronal recordings acquired via Neuropixels 2.0 probes. Performance comparisons with a commercial photodetector device indicate that our system achieves equivalent signal fidelity at a substantially lower cost, while maintaining a minimal footprint suitable for experimental use.
在神经科学实验中呈现视觉刺激通常需要在视觉事件和电生理或行为记录之间进行精确的时间对齐。这通常是通过结合模拟信号来实现的,这些模拟信号传达了液晶显示器(lcd)上显示的视觉线索的时序信息,通过光电探测器感测,并通过模数转换器(ADC)采集板记录。然而,大多数商用光电探测器系统都存在局限性,例如高电压要求,干扰刺激呈现的大传感器足迹,以及与开源平台的有限兼容性。在这里,我们提出了一个紧凑,低成本的光电探测器系统,旨在兼容常见的3.3-5 V基于微控制器的开发板(例如Arduino)和开源的可视化编程语言Bonsai,广泛用于神经科学的实验控制。该电路由一个光电二极管、一个放大级和一个低通滤波器组成,并且可以选择合并一个红外滤波器,用于涉及红外触摸显示器的实验。为了便于再现,我们提供了完整的设计文件、材料清单以及详细的建筑和操作说明。我们进一步介绍了一个四通道变体,能够检测四比特二进制信号,以满足更复杂的同步需求。通过使用Bonsai对LCD显示器进行灰度伽玛校正分析,对该器件进行了验证和表征。此外,我们在头部固定的小鼠实验中展示了该系统的实用性,通过Neuropixels 2.0探针获得的神经元记录同步视觉刺激的发生。与商用光电探测器设备的性能比较表明,我们的系统以更低的成本实现了等效的信号保真度,同时保持了适合实验使用的最小占地面积。
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引用次数: 0
Eight-channel high-speed electrical impedance tomography device implemented on a programmable system on a chip 在芯片上可编程系统上实现的八通道高速电阻抗断层扫描装置
IF 2 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2025-07-09 DOI: 10.1016/j.ohx.2025.e00667
Fausto Andrés Escobar , Carlos Felipe Rengifo , Víctor Hugo Mosquera
This study proposes an electrical impedance tomography (EIT) device based on a programmable system on a chip (PSoc). The EIT-PSoC system is implemented using two PSoC 5LP platforms. A resistive phantom is used to study frame frequency (fps), accuracy (Ac), and signal-to-noise ratio (SNR). A saline phantom, along with both conductive and non-conductive objects, is employed to evaluate the system’s ability to detect changes in impedance distribution. Finally, the dielectric characteristics of the human lower pelvis is emulated using four agar phantoms, allowing an evaluation of the EIT-PSoC system’s performance in response to changes in fluid volume and conductivity. Experiments conducted on the resistive phantom to characterize the EIT-PSoC system demonstrate a frame frequency of 100 fps, a median SNR of 63.59 dB, and an accuracy of 95.39% when using a 0.98 mA sinusoidal current signal at 50 kHz. EIT image reconstruction shows that the proposed system can distinguish impedance changes in the saline phantom. Additionally, by utilizing the global impedance (GI) index and the agar phantoms, the EIT-PSoC system can detect changes in volume and conductivity, making this system a promising alternative for monitoring the volume and conductivity of biological fluids.
本研究提出一种基于片上可编程系统(PSoc)的电阻抗断层扫描(EIT)装置。EIT-PSoC系统使用两个PSoC 5LP平台实现。电阻式模体用于研究帧频(fps)、精度(Ac)和信噪比(SNR)。盐水模体,以及导电和非导电物体,被用来评估系统检测阻抗分布变化的能力。最后,使用四个琼脂模型模拟人体下骨盆的介电特性,从而评估EIT-PSoC系统对流体体积和电导率变化的响应性能。实验表明,当使用0.98 mA的正弦电流信号在50 kHz时,EIT-PSoC系统的帧频率为100 fps,中位信噪比为63.59 dB,精度为95.39%。EIT图像重建结果表明,该系统能够识别生理盐水模体的阻抗变化。此外,通过利用全局阻抗(GI)指数和琼脂幻影,EIT-PSoC系统可以检测体积和电导率的变化,使该系统成为监测生物流体体积和电导率的有希望的替代方案。
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引用次数: 0
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