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Influence of body mass index on early post-operative functional outcomes after total knee arthroplasty: A prospective, clinical and observational study 体重指数对全膝关节置换术后早期功能结局的影响:一项前瞻性、临床和观察性研究
IF 0.3 Q4 ORTHOPEDICS Pub Date : 2023-03-09 DOI: 10.1177/22104917231161834
Rohit M Sane, P. Samant
Background/Purpose: The evidence on the influence of body mass index (BMI) on functional outcomes following total knee arthroplasty (TKA) is conflicting. This study assessed and compared the effect of BMI on early mobility and function after TKA. Methods: Adult patients with osteoarthritis (OA) or rheumatoid arthritis (RA) who received unilateral TKA were recruited and then divided into normal, overweight and obese groups. The pain and functional outcomes of pre/post-TKA were examined using visual analogue scale (VAS) and Lysholm Knee Scale (LKS), respectively. Results: At 3 and 6 weeks post-TKA, LKS score was significantly higher in normal BMI group compared to overweight and obese. Lower BMI gained early improvement in functional outcome than higher BMI groups. However, patients showed considerable functional improvement at 6 months post-TKA, regardless of BMI category. Conclusion: Although BMI levels influence postoperative early functional improvement in TKA patients, the functional benefits after TKA at 6 months were similar regardless of BMI class.
背景/目的:关于身体质量指数(BMI)对全膝关节置换术(TKA)术后功能结局影响的证据是相互矛盾的。本研究评估并比较了BMI对TKA术后早期活动能力和功能的影响。方法:招募接受单侧TKA的成年骨关节炎(OA)或类风湿关节炎(RA)患者,分为正常组、超重组和肥胖组。分别采用视觉模拟量表(VAS)和Lysholm膝关节量表(LKS)检测tka前后的疼痛和功能结局。结果:tka后3周和6周,BMI正常组的LKS评分明显高于超重和肥胖组。较低BMI组较高BMI组在功能预后方面得到早期改善。然而,无论BMI类别如何,患者在tka后6个月均表现出相当大的功能改善。结论:尽管BMI水平影响TKA患者术后早期功能改善,但无论BMI级别如何,TKA术后6个月功能获益相似。
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引用次数: 0
Distal femur varus-producing osteotomy: An updated review of patellofemoral implications and clinical outcomes 股骨远端内翻截骨术:髌股影响和临床结果的最新综述
IF 0.3 Q4 ORTHOPEDICS Pub Date : 2023-02-07 DOI: 10.1177/22104917221147687
Garibaldi Riccardo, T. Bonanzinga, F. M. Gambaro, Michele Palazzuolo, F. Iacono, M. Marcacci
Background: Recent evidence seems to suggest the effectiveness of distal femur varus osteotomy in the management of patellofemoral instability in the setting of genu valgum. However, literature on this subject remains scarce and consists mostly of small case series. Hypothesis: This study aims to systematically review the literature on varus-producing distal femur osteotomy and critically analyze its implications on patellofemoral kinematics and stability. Results: The statistical analysis revealed that this surgery is able to restore a mechanical angle (mean hip–knee–ankle (HKA): 0.22°) and to improve the main clinical outcomes (Kujala score, Knee injury and Osteoarthritis Outcome Score, visual analog scale) after a mean follow up of 2.5 years. An objective of the present review was to investigate the mechanical implications of femoral osteotomy on the patellofemoral biomechanics. Indeed, the statistical analysis demonstrated changes after surgery in the main patella-femoral radiological angles (modified Insall–Salvati index, Caton–Deschamps index, Blackburne–Peel index). Interestingly the overcorrection of the mechanical axis (HKA), resulting in varus, had similar outcomes compared to studies that obtained a mechanical axis. Level of Evidence: Level II study.
背景:最近的证据似乎表明股骨远端内翻截骨术在治疗膝外翻型髌骨不稳定方面是有效的。然而,关于这一主题的文献仍然很少,并且主要由小病例系列组成。假设:本研究旨在系统地回顾有关产生内翻的股骨远端截骨术的文献,并批判性地分析其对髌骨运动学和稳定性的影响。结果:统计分析显示,经过平均2.5年的随访,该手术能够恢复机械角度(平均髋关节-膝关节-踝关节(HKA): 0.22°),并改善主要临床结果(Kujala评分,膝关节损伤和骨关节炎结局评分,视觉模拟量表)。本综述的目的是研究股骨截骨术对髌股生物力学的力学影响。事实上,统计分析显示手术后髌骨-股骨主要放射角度(改良的Insall-Salvati指数、Caton-Deschamps指数、blackburn - peel指数)发生了变化。有趣的是,机械轴(HKA)的过度矫正导致内翻,与获得机械轴的研究结果相似。证据等级:II级研究。
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引用次数: 0
What can we expect from patellar denervation in knee arthroplasty? An updated systematic review and meta-analysis 膝关节置换术中髌骨去神经能带来什么?最新的系统综述和荟萃分析
IF 0.3 Q4 ORTHOPEDICS Pub Date : 2023-02-01 DOI: 10.1177/22104917221150533
I. Wayan, Suryanto Dusak, Kartini Ciatawi, Wayan Subawa, P. Eyanoer
Denervation by electrocauterization was proposed to be efficient in preventing anterior knee pain (AKP) following arthroplasty. The purpose of this study was to evaluate the effects of patellar denervation (PD) in primary knee arthroplasty. Systematic search was performed in PubMed, ScienceDirect, Cochrane Library, and ClinicalKey databases until July 2022 for published articles. The quantitative analyses were carried out by Review Manager 5.4 software. Twenty-one studies were included. Overall incidence of AKP, visual analog scale (VAS), and knee society score were significantly superior in PD group. Denervation also showed better outcomes in incidence of AKP at each follow-up time point, and in VAS and range of motion (ROM) at ≤3 months. Subanalyses based on depth of electrocautery showed statistically better results with 2–3 mm depth in VAS and PS compared to ≤1 mm. This study concluded that PD might contribute to lower incidence of knee pain. Patients who expect quicker recovery in pain and ROM may benefit from this procedure.
电烧灼去神经是预防膝关节置换术后前膝关节疼痛(AKP)的有效方法。本研究的目的是评估髌骨去神经支配(PD)在原发性膝关节置换术中的效果。系统检索PubMed、ScienceDirect、Cochrane Library和ClinicalKey数据库,直至2022年7月检索已发表的文章。定量分析由Review Manager 5.4软件进行。纳入了21项研究。PD组AKP总发生率、视觉模拟量表(VAS)、膝关节社会评分均显著高于PD组。在每个随访时间点的AKP发生率以及≤3个月的VAS和活动度(ROM)方面,去神经支配也显示出更好的结果。基于电灼深度的亚分析显示,VAS和PS深度为2-3 mm的结果优于≤1 mm的结果。本研究的结论是帕金森病可能有助于降低膝关节疼痛的发生率。期望疼痛和ROM更快恢复的患者可能会从该手术中受益。
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引用次数: 0
Clinical outcomes of a standardized rehabilitation protocol for meniscal repair: A retrospective case series 半月板修复标准化康复方案的临床结果:回顾性病例系列
IF 0.3 Q4 ORTHOPEDICS Pub Date : 2023-01-22 DOI: 10.1177/22104917221144723
Gavin Cho wai Lam, Ramon Lo Yiu, Y. Leung
Background/Purpose: To examine clinical and functional outcomes of patients who underwent meniscal repair with a modified accelerated rehabilitation program. Methods: This study represents a case series of patients who underwent meniscal repair from 2017 to 2019. The mean patient age was 26.6 (range: 15–47) years. Of the 28 total patients, 22 had concomitant anterior cruciate ligament tears that were treated with single-bundle hamstring reconstruction at the time of meniscal repair. All patients were enrolled in a standardized rehabilitation program, allowing early-phase protected weight-bearing and knee mobilization. Patient-reported symptoms, the McMurray test, and the International Knee Documentation Committee (IKDC) were used to evaluate outcomes. The mean follow-up period was 13 ± 3.1 (range: 9–20) months. Results: Of the participating patients, 75% (22 of 28) returned to their original sports activities. Most patients displayed satisfactory clinical outcomes with significant improvements in IKDC scores. No re-tears were detected. Conclusion: Early protected weight-bearing with progressive early knee mobilization is a safe rehabilitation option after meniscal repair.
背景/目的:研究采用改良加速康复方案进行半月板修复的患者的临床和功能预后。方法:选取2017 - 2019年接受半月板修复的患者为研究对象。患者平均年龄为26.6岁(15-47岁)。在28例患者中,22例合并前交叉韧带撕裂,在半月板修复时采用单束腘绳肌重建治疗。所有患者都参加了标准化的康复计划,允许早期保护负重和膝关节活动。患者报告的症状、McMurray试验和国际膝关节文献委员会(IKDC)用于评估结果。平均随访时间为13±3.1(范围:9-20)个月。结果:在参与研究的患者中,75%(22 / 28)的患者恢复了原来的体育活动。大多数患者表现出满意的临床结果,IKDC评分显著提高。未检测到再撕裂。结论:半月板修复后,早期保护性负重和渐进式早期膝关节活动是一种安全的康复选择。
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引用次数: 0
How do dislocation rates differ between different approaches to total hip arthroplasty? A systematic review and meta-analysis 不同的全髋关节置换术中脱位率有何不同?系统回顾和荟萃分析
IF 0.3 Q4 ORTHOPEDICS Pub Date : 2023-01-17 DOI: 10.1177/22104917221147688
Marc Koster, Anton D Luzier, O. Temmerman, S. Vos, Joyce L Benner
Background: Different surgical approaches for total hip arthroplasty (THA) exist, without predisposition when it comes to dislocation risk. The direct anterior approach (DAA) is thought to have reduced risk since soft tissue trauma is minimalized. Therefore, we assessed the dislocation risk for different surgical approaches, and the relative dislocation risk of DAA compared to other approaches. Methods: Six electronic databases were systematically searched for prospective studies reporting dislocation following THA. Proportion meta-analyses were performed to assess the dislocation rate for subgroups of the surgical approach. Meta-analysis for binary outcomes was performed to determine the relative risk of dislocation for the DAA compared to other approaches. Results: Eleven studies with 2025 patients were included (mean age 64.6 years, 44% male, mean follow-up 10.5 months), of which four studies were also used in the risk ratio meta-analysis. Overall dislocation rate was 0.79% (95% CI 0.37–1.69). Subgroup analyses showed that most dislocations occurred in the posterior approaches group (1.38%), however non-significant. Furthermore, the DAA emerged with a non-significant lower risk of dislocation (RR 0.37, 95% CI 0.05–2.46) compared to other surgical approaches. Conclusion: Current literature shows non-significant predisposition for a surgical approach to THA regarding dislocation risk. To what extent patient characteristics influence the risk of dislocation could not be determined. Future research should focus on this, as well as on the influence of a surgeon's experience with a specific approach.
背景:全髋关节置换术(THA)有不同的手术入路,当涉及到脱位风险时没有易感性。直接前路入路(DAA)被认为具有较低的风险,因为软组织损伤最小。因此,我们评估了不同手术入路的脱位风险,以及DAA与其他入路相比的相对脱位风险。方法:系统检索6个电子数据库中报道THA术后脱位的前瞻性研究。采用比例荟萃分析来评估手术入路亚组的脱位率。对二元结果进行荟萃分析,以确定与其他方法相比DAA脱位的相对风险。结果:纳入11项研究,共纳入2025例患者(平均年龄64.6岁,男性44%,平均随访10.5个月),其中4项研究也用于风险比荟萃分析。总体脱位率为0.79% (95% CI 0.37-1.69)。亚组分析显示大多数脱位发生在后路组(1.38%),但无统计学意义。此外,与其他手术入路相比,DAA出现脱位的风险无显著性降低(RR 0.37, 95% CI 0.05-2.46)。结论:目前的文献显示手术入路对THA脱位风险的影响不显著。患者特征对脱位风险的影响程度尚不清楚。未来的研究应该集中在这一点上,以及外科医生的经验对特定方法的影响。
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引用次数: 0
Effectiveness of continuous passive motion in total knee replacement patients with slow rehabilitation under ERAS pathway ERAS途径下全膝关节置换术患者持续被动运动的疗效
IF 0.3 Q4 ORTHOPEDICS Pub Date : 2023-01-12 DOI: 10.1177/22104917221150532
Chau Ming Hong, Lee Qunn Jid, Chang Wai Yee Esther
Background: Although we know routine use of continuous passive motion (CPM) has no clinical benefit on patients’ outcome after total knee replacement (TKR), the effect of CPM on patients with poor rehabilitation progress under ERAS (Enhanced Recovery after Surgery) pathway is unclear. We aimed to evaluate the clinical outcomes by using CPM in these patients under ERAS pathway. Methods: We performed a retrospective study for patients who had TKR done between 2017 and 2019 under ERAS pathway. Patients who were not able to reach 45 degrees of active range of movement (ROM) on postoperative day (POD) 3 would be reviewed to see if any CPM was used. Primary outcomes were the length of hospital stay and the active ROM upon discharge. Other outcomes were the active ROM in POD4 and the latest follow-up, pain score, and quadriceps power. Result: After exclusion, total of 68 patients were included in the study, with 30 were given CPM and 38 were not. Both groups had matched demographics. The study (CPM) group had significantly higher mean active ROM upon discharge (76.00 vs 68.42 degrees, p = 0.02) and longer hospital stay (7.3 vs 5.9 days, p =0.01). There were no significant effects on pain score, quadriceps power, and the active ROM in POD4 and the latest follow-up. Conclusion: For post TKR patients with limited rehabilitation progress under ERAS pathway, the use of CPM could attain better active ROM upon discharge with no adverse effect on pain control and quadriceps power, but at the expense of an increase in the length of stay.
背景:虽然我们知道常规使用持续被动运动(CPM)对全膝关节置换术(TKR)后患者的预后没有临床益处,但在ERAS(术后增强恢复)途径下,CPM对康复进展较差的患者的影响尚不清楚。我们的目的是评估这些患者在ERAS途径下使用CPM的临床结果。方法:我们对2017年至2019年在ERAS途径下进行TKR的患者进行了回顾性研究。术后一天(POD) 3不能达到45度活动范围(ROM)的患者将复查是否使用CPM。主要结局是住院时间和出院时的活动度。其他结果包括POD4的活动活动度、最新随访、疼痛评分和股四头肌力量。结果:经排除,共纳入68例患者,其中30例给予CPM治疗,38例未给予CPM治疗。两组的人口统计数据相匹配。CPM组患者出院时平均活动度明显高于对照组(76.00 vs 68.42度,p = 0.02),住院时间明显延长(7.3 vs 5.9天,p =0.01)。在POD4和最新随访中,疼痛评分、股四头肌力量和活动ROM均无显著影响。结论:对于ERAS途径下康复进展有限的TKR后患者,使用CPM可以在出院时获得更好的活动ROM,对疼痛控制和股四头肌力量无不良影响,但以增加住院时间为代价。
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引用次数: 1
Correlation between presence of traumatic disco-ligamentous injuries as an MRI finding with the results of management of thoracolumbar and lumbar injuries 外伤性椎间盘韧带损伤的MRI表现与胸腰椎和腰椎损伤处理结果的相关性
IF 0.3 Q4 ORTHOPEDICS Pub Date : 2023-01-12 DOI: 10.1177/22104917221147690
Tarek Aly
Introduction: Radiographic study plays an important role in diagnosis of acute vertebral injuries and helps in proper management of those patients. Magnetic resonance imaging (MRI) is the modality of choice for evaluation of ligamentous and other soft tissue structures, disc, spinal cord and occult osseous injuries. Due to high cost, it is necessary to detect the best use of this technique in the evaluation of thoracolumbar spinal injuries. The purpose of this study was to evaluate the importance of MRI as indicators for vertebral ligamentous injuries and intervertebral disc injuries or herniation in management of thoracolumbar and lumbar fractures. Methods: Retrospective study using radiological measurements. Seventy-two patients with thoracolumbar and lumbar fractures were included. Radiographic parameters detected were percentage of compression, kyphosis angle, vertebral translation and scoliosis angle. Computed tomography was used to detect the degree of spinal canal narrowing, MRI was used to evaluate the condition of posterior ligamentous complex and intervertebral disc injury or herniation. American Spinal Injury Association score was recorded. Results: There were 83% AO spine type A, 6% AO spine type B and 11% AO spine type C. Correlation between fracture type and neurological status with the posterior ligamentous complex injury was found to be significant: (P = 0.0143 and P = 0.0344, respectively). Degree of vertebral body compression, kyphosis and scoliosis angles, vertebral body translation and spinal canal narrowing were found to be insignificant in correlation with posterior ligamentous complex injuries. Correlation of the above-mentioned parameters with disc injury or herniation was found to be insignificant except for kyphotic angle that was found to be significant in correlation with posttraumatic disc herniation (P = 0.0219). Conclusion: MRI finding is of great value in management plan of thoracolumbar and lumbar fractures. Injury of posterior ligamentous complex is significantly correlated with fracture severity and the neurological function. But the intervertebral disc injury or herniation was not correlated to them except that the disc herniation was significantly correlated to kyphosis angle.
放射学研究在急性椎体损伤的诊断和治疗中起着重要的作用。磁共振成像(MRI)是评估韧带和其他软组织结构、椎间盘、脊髓和隐性骨损伤的首选方式。由于成本高,有必要确定该技术在胸腰椎损伤评估中的最佳应用。本研究的目的是评估MRI作为椎韧带损伤和椎间盘损伤或突出的指标在胸腰椎骨折治疗中的重要性。方法:采用放射学测量进行回顾性研究。纳入72例胸腰椎骨折患者。影像学参数检测为压缩率、后凸角、椎体平移和脊柱侧凸角。ct检查椎管狭窄程度,MRI检查后韧带复合体及椎间盘损伤或突出情况。记录美国脊髓损伤协会评分。结果:A型AO占83%,B型AO占6%,c型AO占11%。骨折类型与神经功能状态与后韧带复合体损伤有显著相关性(P = 0.0143, P = 0.0344)。椎体受压程度、后凸和脊柱侧凸角度、椎体平移和椎管狭窄与后韧带复合体损伤的相关性不显著。除后凸角度与创伤后椎间盘突出相关外,上述参数与椎间盘损伤或椎间盘突出的相关性均不显著(P = 0.0219)。结论:MRI表现对胸腰椎骨折的治疗方案有重要价值。后韧带复合体损伤与骨折严重程度及神经功能显著相关。但椎间盘损伤或突出与它们无关,椎间盘突出与后凸角显著相关。
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引用次数: 0
A retrospective study of articular surface mounting computer-assisted total knee arthroplasty in alignment, knee function, and survival 关节面安装计算机辅助全膝关节置换术对膝关节对齐、功能和生存的回顾性研究
IF 0.3 Q4 ORTHOPEDICS Pub Date : 2023-01-10 DOI: 10.1177/22104917221144700
Eugene Pak-Lin Ng, H. Wong
Background Hong Kong Chinese exhibits a greater varus lower limb mechanical axis and coronal bowing when compared to Caucasians. This anatomical difference may affect the accuracy of bone cuts in total knee arthroplasty (TKA) using western anatomy-based intramedullary TKA cutting jigs. Use of computer navigation may avoid suboptimal cuts due to altered anatomy. This is the first study evaluating clinical function, radiological alignment and long-term survival of computer-assisted TKA amongst Hong Kong Chinese patients. Methods Retrospective study comparing articular surface mounting computer-assisted TKA (ASM-CATKA) and conventional TKA performed in a single centre from 2008 to 2010. Patients were followed up for assessment of clinical parameters including range of motion, Knee Society Knee score, and radiological parameters such as limb alignment, component alignment, and survival. Results Seventy-five patients were included in this study. Baseline clinical and radiological data were similar between groups. The computer-navigated group had superior radiological mechanical alignment (p < 0.001), tibial component alignment (p = 0.016) and femoral component alignment (p < 0.01) when compared to conventional TKA. There were no differences in knee scores (p = 0.488), range of motion (p = 0.432) and survival at 117 months (p = 0.986) between the two groups. Conclusion This retrospective study showed that ASM-CATKA was more accurate in achieving neutral mechanical axis and component alignment amongst Hong Kong Chinese. Clinical outcomes and implant survival were comparable.
背景与白种人相比,香港华人表现出更大的下肢机械轴内翻和冠状弓。这种解剖学上的差异可能会影响全膝关节置换术(TKA)中使用基于西方解剖学的髓内TKA切割夹具时骨切割的准确性。使用计算机导航可以避免因解剖结构改变而导致的次优切口。这是首个在香港华人患者中评估计算机辅助TKA的临床功能、放射学对齐和长期生存的研究。方法回顾性比较2008 ~ 2010年在单中心进行的关节面安装计算机辅助TKA (ASM-CATKA)和传统TKA。对患者进行随访,评估临床参数,包括活动范围、膝关节学会评分、放射学参数,如肢体对齐、部件对齐和生存率。结果本研究共纳入75例患者。两组之间的基线临床和放射学数据相似。与传统TKA相比,计算机导航组放射学机械对齐(p < 0.001)、胫骨组件对齐(p = 0.016)和股骨组件对齐(p < 0.01)均优于传统TKA。两组患者的膝关节评分(p = 0.488)、活动范围(p = 0.432)和117个月生存率(p = 0.986)均无差异。结论本回顾性研究显示ASM-CATKA在香港华人中更准确地实现中性机械轴和部件对准。临床结果和种植体存活比较。
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引用次数: 0
Early or delay? The most suitable rehabilitation protocol for “no man's land” injury: Meta-analysis with trial sequential analysis—20 years trends 提前还是推迟?最适合“无人区”损伤的康复方案:荟萃分析与试验序列分析- 20年趋势
Q4 ORTHOPEDICS Pub Date : 2023-01-04 DOI: 10.1177/22104917221147686
Celleen Rei Setiawan, Made Bramantya Karna, Andrew Sutheno, Febyan Febyan, Dary Gunawan
Objective: The aim of this study is to analyze various rehabilitation protocol and determine which methods will yield a better outcome. Methods: The database reports were searched within 1990 until 2020, using PubMed, Cochrane library database, Ovid, Medline, and the other several published trials. A statistical analysis was made from Review Manager and Trial Sequential Analysis (TSA). Result: The mean of rerupture rate is 3.3% (n = 8) in the combination protocol and 8% (n = 48) in controlled active motion (CAM) protocol. Meta-analysis found no significant difference between Kleinert versus CAM in rerupture rate. Furhtermore, we found no significant difference in Duran versus CAM in rerupture rate. In TSA, the Z-curve does not cross both of the trial sequential boundaries, a further trial with larger sample will be required. The TSA of flexion contracture CAM versus Kleinert was indicated that CAM protocol may be superior than Kleinert to reduce the incidence of flexion contracture with the range of mean flexion contracture 6.6% (n = 18) in CAM to 23.6% (n = 76) in Kleinert protocol. Conclusion: Current meta-analysis proposed that the combination technique will result less rerupture incidence and better functional outcome in flexor zone II injuries than other techniques. The CAM method also results in less flexion contracture than others. However, a further meta-analysis with larger sample trials seems to be required to confirm this review's conclusion.
目的:本研究的目的是分析各种康复方案,确定哪种方法会产生更好的结果。方法:检索1990年至2020年间的数据库报告,使用PubMed、Cochrane图书馆数据库、Ovid、Medline和其他几项已发表的试验。由评审管理和试验序列分析(TSA)进行统计分析。结果:联合治疗组的平均再破裂率为3.3% (n = 8),可控主动运动治疗组的平均再破裂率为8% (n = 48)。meta分析发现Kleinert与CAM在再破裂率上无显著差异。此外,我们发现Duran和CAM在再破裂率上没有显著差异。在TSA中,z曲线没有跨越两个试验序列边界,则需要使用更大的样本进行进一步的试验。屈曲挛缩CAM与Kleinert的TSA对比表明,CAM方案在降低屈曲挛缩发生率方面可能优于Kleinert方案,CAM方案的平均屈曲挛缩率为6.6% (n = 18), Kleinert方案的平均屈曲挛缩率为23.6% (n = 76)。结论:目前的荟萃分析表明,与其他技术相比,联合技术可减少屈肌II区损伤的再破裂发生率和更好的功能预后。CAM方法也导致屈曲挛缩比其他方法少。然而,似乎需要更大样本试验的进一步荟萃分析来证实这一综述的结论。
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引用次数: 0
The effect and safety of periarticular multimodal drug injection without morphine and epinephrine in anterior cruciate ligament reconstruction 不含吗啡和肾上腺素的关节周围多模态药物注射在前交叉韧带重建中的效果和安全性
IF 0.3 Q4 ORTHOPEDICS Pub Date : 2022-12-13 DOI: 10.1177/22104917221136285
Changhun Han, Yusuke Hashimoto, Sunao Nakagawa, S. Takahashi, Yohei Nishida, S. Yamasaki, J. Takigami, Hiroaki Nakamura
Background Periarticular multimodal drug injection (PMDI) is a safe and effective pain management technique after anterior cruciate ligament reconstruction (ACLR); however, adding morphine and epinephrine sometimes causes adverse effects. Therefore, we evaluated the efficacy of PMDI without morphine and epinephrine after ACLR. Methods This retrospective matched case-control study included patients who had undergone primary double-bundle ACLR with PMDI and were then matched one-to-one with a control group without PMDI based on sex, age, and body mass index using propensity-matched analysis. The following clinical outcomes were compared between the groups: visual analog scale (VAS) score, C-reactive protein (CRP) concentration, number of times the patients used additional analgesics, complication rate, and postoperative time to achieve straight leg raise (SLR). Results Twenty-nine patients with PMDI and 29 controls were enrolled. The VAS score at 1 day postoperatively was lower in the PMDI than the control group (1.93  ±  1.44 vs. 3.41  ±  1.75, respectively; P < 0.001). The CRP concentration at 1 and 3 days was lower in the PMDI than the control group (0.46  ±  0.47 vs. 1.00  ±  0.69 mg/dL, P < 0.001; and 1.93  ±  1.71 vs. 4.01  ±  2.55 mg/dL, P < 0.001, respectively). The average number of additional analgesics used was significantly lower in the PMDI than the control group. There were no significant differences in the frequency of occurrence of postoperative complications between the two groups. The number of patients who could achieve SLR within 1 day was 27/29 (93%) in PMDI group, which was significantly higher than the control group (12/29, 41%) (P < 0.001). Conclusion PMDI without morphine and epinephrine after ACLR reduced patients’ subjective pain level, objective inflammatory response without complications and enabled patients to achieve early functional recovery.
背景:关节周围多模态药物注射(PMDI)是前交叉韧带重建(ACLR)后安全有效的疼痛管理技术;然而,添加吗啡和肾上腺素有时会引起不良反应。因此,我们评价ACLR术后不加吗啡和肾上腺素的PMDI的疗效。方法本回顾性匹配病例对照研究纳入了行原发性双束ACLR合并PMDI的患者,然后根据性别、年龄和体重指数采用倾向匹配分析与未行PMDI的对照组进行一对一匹配。比较两组间的临床结果:视觉模拟评分(VAS)评分、c反应蛋白(CRP)浓度、患者额外使用镇痛药次数、并发症发生率、术后达到直腿抬高(SLR)时间。结果入选PMDI患者29例,对照组29例。PMDI组术后1 d VAS评分低于对照组(分别为1.93±1.44∶3.41±1.75);p < 0.001)。PMDI组第1天和第3天CRP浓度低于对照组(0.46±0.47 vs 1.00±0.69 mg/dL, P < 0.001;和1.93±1.71和4.01±2.55 mg / dL, P < 0.001,分别)。PMDI组额外使用镇痛药的平均数量明显低于对照组。两组患者术后并发症发生频率差异无统计学意义。PMDI组患者在1 d内达到SLR的人数为27/29(93%),显著高于对照组(12/29,41%)(P < 0.001)。结论ACLR术后不使用吗啡和肾上腺素的PMDI降低了患者的主观疼痛水平和客观炎症反应,无并发症,使患者早日实现功能恢复。
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Journal of Orthopaedics Trauma and Rehabilitation
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