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Magnetic Nanoparticles Mediated Thrombolysis–A Review 磁性纳米颗粒介导的血栓溶解——综述
IF 1.7 Q3 Engineering Pub Date : 2023-03-08 DOI: 10.1109/OJNANO.2023.3273921
Bohua Zhang;Xiaoning Jiang
Nanoparticles containing thrombolytic medicines have been developed for thrombolysis applications in response to the increasing demand for effective, targeted treatment of thrombosis disease. In recent years, there has been a great deal of interest in nanoparticles that can be navigated and driven by a magnetic field. However, there are few review publications concerning the application of magnetic nanoparticles in thrombolysis. In this study, we examine the current state of magnetic nanoparticles in the application of in vitro and in vivo thrombolysis under a static or dynamic magnetic field, as well as the combination of magnetic nanoparticles with an acoustic field for dual-mode thrombolysis. We also discuss four primary processes of magnetic nanoparticles mediated thrombolysis, including magnetic nanoparticle targeting, magnetic nanoparticle trapping, magnetic drug release, and magnetic rupture of blood clot fibrin networks. This review will offer unique insights for the future study and clinical development of magnetic nanoparticles mediated thrombolysis approaches.
含有溶栓药物的纳米颗粒已被开发用于溶栓应用,以响应对血栓形成疾病的有效靶向治疗日益增长的需求。近年来,人们对可以通过磁场导航和驱动的纳米粒子产生了极大的兴趣。然而,关于磁性纳米颗粒在溶栓中的应用的综述文献很少。在本研究中,我们考察了磁性纳米颗粒在静态或动态磁场下体外和体内溶栓的应用现状,以及磁性纳米颗粒与声场结合进行双模溶栓的情况。我们还讨论了磁性纳米颗粒介导的溶栓的四个主要过程,包括磁性纳米颗粒靶向、磁性纳米颗粒捕获、磁性药物释放和血凝块纤维蛋白网络的磁性破裂。这一综述将为磁性纳米颗粒介导的溶栓方法的未来研究和临床发展提供独特的见解。
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引用次数: 0
Guest Editorial: Materials & Devices for Advanced Flexible Sensors 嘉宾评论:先进柔性传感器的材料与器件
IF 1.7 Q3 Engineering Pub Date : 2023-02-03 DOI: 10.1109/OJNANO.2023.3238959
Yu Xinge
The papers in this special section focus on materials and devices for flexible sensors. Presents recent advances in skin electronics, touch sensors for flexible display, near-infrared spectroscopy (NIRS) and organic electrochemical transistors (OECT), respectively. Three research article introduces new methods in flexible pressure sensing array, ammonia sensors and charge plasma junctionless tunnel field effect transistor (CP JLTFET), respectively.
这一特殊部分的论文主要关注柔性传感器的材料和器件。分别介绍了皮肤电子学、柔性显示触摸传感器、近红外光谱(NIRS)和有机电化学晶体管(OECT)的最新进展。三篇研究文章分别介绍了柔性压力传感阵列、氨传感器和电荷等离子体无结隧道场效应晶体管(CP JLTFET)的新方法。
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引用次数: 0
Dirac Materials and an Identity for the Grand Potential of the Nondegenerate Statistical Thermodynamic Regime 狄拉克材料与非简并统计热力学体系的大势恒等式
IF 1.7 Q3 Engineering Pub Date : 2023-01-10 DOI: 10.1109/OJNANO.2023.3234042
NORMAN J. M. HORING
We examine the question “Can Dirac materials exist in a nondegenerate statistical state?,” deriving and employing an identity for the thermodynamic Grand Potential $Omega$ (per unit volume/area) in the low density nondegenerate statistical regime, relating it to the density $n$ as $Omega = -beta ^{-1} n$ ($beta ^{-1} = kappa _{B} T$ is thermal energy, $kappa _{B}$ is the Boltzmann constant, and $T$ is Kelvin temperature). The implications of this identity for Dirac materials are explored. The identity is universally valid for all thermodynamic systems in equilibrium in the nondegenerate, low density statistical regime, irrespective of size, dimensionality or applied static fields. Phenomena that may contribute to the realization of such a nondegenerate statistical equilibrium state in Dirac materials are discussed.
我们考察了“狄拉克材料能否存在于非简并统计状态?”在低密度非简并统计体系中,推导并采用热力学大势$Omega$(每单位体积/面积)的恒等式,将其与密度$n$联系为$Omega = -beta ^{-1} n$ ($beta ^{-1} = kappa _{B} T$为热能,$kappa _{B}$为玻尔兹曼常数,$T$为开尔文温度)。对狄拉克材料的这种同一性的含义进行了探讨。这一恒等式对所有处于非简并、低密度统计体系平衡状态的热力学系统是普遍有效的,与大小、维数或施加的静态场无关。讨论了可能有助于在狄拉克材料中实现这种非简并统计平衡态的现象。
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引用次数: 0
Greenhouse Gas Detection Based on Infrared Nanophotonic Devices 基于红外纳米光子器件的温室气体检测
IF 1.7 Q3 Engineering Pub Date : 2023-01-06 DOI: 10.1109/OJNANO.2022.3233485
Chunhui Hao;Xiao Fu;Xiaoyong Jiang;Yutong Li;Juyi Sun;Haitao Wu;He Zhu;Qing Li;Yunhai Li;Zhangcheng Huang;Fang Zhong;Ting He;Jinshui Miao;Weida Hu
Most greenhouse gases come from biological activities and industry which will lead to global warming and show an impact on human life. With the need of green transformation of the global economic structure and seeking for higher quality of human life, the detection and management of greenhouse gases, as well as most hazardous gases in the environment, are increasingly demanding. Applications in different fields require sensors that can detect gas volume fractions with magnitudes from 10–9 to 10–4. Greenhouse gas detection plays an important role both in the agriculture and industry field. In this review, we first summarize the mechanism of several common gas detectors used currently. Then, the advantages of nanostructured gas sensors are discussed. Finally, the applications of infrared gas sensors based on nanophotonic devices are described in detail. This review has been an outlook on the future development of infrared gas sensors based on nanophotonic devices.
大多数温室气体来自生物活动和工业,它们会导致全球变暖,并对人类生活产生影响。随着全球经济结构绿色转型的需要和对人类生活质量的追求,对温室气体以及环境中大多数有害气体的检测和管理提出了越来越高的要求。不同领域的应用需要能够检测10-9到10-4量级气体体积分数的传感器。温室气体检测在农业和工业领域都发挥着重要作用。本文首先综述了目前常用的几种气体检测仪的检测机理。然后,讨论了纳米结构气体传感器的优点。最后,详细介绍了基于纳米光子器件的红外气体传感器的应用。本文对基于纳米光子器件的红外气体传感器的未来发展进行了展望。
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引用次数: 0
2023 Index IEEE Open Journal of Nanotechnology Vol. 4 2023 Index IEEE Open Journal of Nanotechnology Vol.
IF 1.7 Q3 Engineering Pub Date : 2023-01-01 DOI: 10.1109/OJNANO.2024.3362684
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引用次数: 0
Modelling, Fabrication and Testing of RF Micro-Electro-Mechanical-Systems Switch 射频微机电系统开关的建模、制造和测试
IF 1.7 Q3 Engineering Pub Date : 2022-12-26 DOI: 10.1109/OJNANO.2022.3232182
Srinivasa Rao Karumuri;P. Ashok Kumar;Girija Sravani Kondavitee;Aime Lay-Ekuakille
This paper presents an approach to evaluate capacitance developed by perforated membrane of RF MEMS switch with high accuracy. An analytical model is developed for both upstate and downstate of switch by including parasitic and fringing field capacitance in parallel plate capacitance model. The proposed analytical model includes the ligament efficiency term directly in the formula which reduce the efforts to calculate it individually for various perforation sizes. The capacitance analysis has been carried out by varying the physical parameters to optimize the switch dimensions and these analytical results are compared with the simulation results carried out by 3D FEM tool COMSOL multiphysics for validation. The proposed analytical model results are then compared with benchmark models to understand the efficiency of proposed model in estimating the up and downstate capacitances. The proposed analytical model proved to be good with less error percentage of 2.13% at upstate and 2.59% at downstate whereas the other benchmark models gives greater than 5% error. The switch is then fabricated using 4-mask surface micromachining process and experimental evaluation of capacitance at both upstate and downstate is carried out by DC probe station. Experimentally, the upstate capacitance is obtained as 37.4 fF and downstate as 2.43 pF and the analytical models exhibited low error percentage of 3.95% at upstate and 2.05% at downstate condition for µ = 0.5.
本文提出了一种高精度评估射频MEMS开关穿孔膜电容的方法。在并联板电容模型中加入寄生场电容和边缘场电容,建立了开关上、下两种状态的解析模型。所提出的分析模型将韧带效率项直接包含在公式中,减少了对不同穿孔尺寸单独计算的工作量。通过改变物理参数来优化开关尺寸,进行了电容分析,并将分析结果与COMSOL multiphysics三维有限元工具的仿真结果进行了对比验证。然后将所提出的分析模型结果与基准模型进行比较,以了解所提出的模型在估计上下状态电容方面的效率。结果表明,该分析模型误差较小,上状态误差为2.13%,下状态误差为2.59%,而其他基准模型误差均大于5%。然后采用四掩模表面微加工工艺制作开关,并利用直流探头站对开关上、下状态电容进行了实验评估。实验结果表明,在μ = 0.5条件下,上态电容为37.4 fF,下态电容为2.43 pF,上态误差为3.95%,下态误差为2.05%。
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引用次数: 0
Guest Editorial: Nanopackaging Part II 嘉宾评论:纳米包装第二部分
IF 1.7 Q3 Engineering Pub Date : 2022-12-23 DOI: 10.1109/OJNANO.2022.3224652
Attila Bonyar;Brajesh Kumar Kaushik;James E. Morris;Markondeyaraj Pulugurtha
The papers in this special section focus on nanopackaging. It begins with three reviews of diverse nanoscale technologies and then moves on to research papers focused primarily on nanomaterials for on-chip interconnect and noise abatement.
在这个特殊的部分的论文集中在纳米包装。它首先回顾了三种不同的纳米技术,然后转向研究论文,主要集中在芯片上互连和降噪的纳米材料上。
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引用次数: 0
Transition Metal Doped Bismuthene and Mn-Bi/CrI3 Heterostructure for High Anisotropy Energy and Half-Metallicity 高各向异性能和半金属丰度的过渡金属掺杂铋和Mn-Bi/CrI3异质结构
IF 1.7 Q3 Engineering Pub Date : 2022-12-22 DOI: 10.1109/OJNANO.2022.3231436
Shipra Saini;Namita Bindal;Brajesh Kumar Kaushik
Magnetic anisotropy energy (MAE) of two-dimensional (2D) magnetic materials is the key parameter for designing next-generation spintronic devices. Here, using first-principle calculations based on density functional theory (DFT), the variance in MAE and other magnetic properties is observed for transition metal (TM) doped bismuth monolayer (bismuthene). This doped system shows a significant modulation in the magnetic moment, MAE, Curie temperature Tc, and charge transfer. However, Mn-doped bismuthene exhibits half-metallicity with a maximum magnetic moment of 4μB (Bohr magneton) that is 17% higher than Fe-doped bismuthene. The maximum MAE extracted for Mn-doped bismuthene is 27.51% higher than the Ti-doped system. On the basis of these findings, the electronic and magnetic characteristics of Mn-doped bismuthene (Mn-Bi) and monolayer CrI3 van der Waals (vdW) heterostructures are also investigated. In Mn-Bi/CrI3 van der Waals heterostructure, the half-metal Mn-Bi can induce the half-metallicity in CrI3 through charge transfer. Compared to other doped systems, Mn-Bi presents the most favorable magnetic properties. Thus, Mn-Bi/CrI3 heterostructure paves the path for the development of spintronic devices.
二维磁性材料的磁各向异性能(MAE)是设计下一代自旋电子器件的关键参数。本文利用基于密度泛函理论(DFT)的第一性原理计算,观察了过渡金属(TM)掺杂铋单层(bismuthene)的MAE和其他磁性能的变化。该掺杂体系在磁矩、MAE、居里温度Tc和电荷转移方面表现出明显的调制作用。mn掺杂铋具有半金属性,最大磁矩为4μB(玻尔磁子),比fe掺杂铋高17%。mn掺杂铋体系的最大MAE提取率比ti掺杂体系高27.51%。在此基础上,研究了mn掺杂铋(Mn-Bi)和单层CrI3 van der Waals (vdW)异质结构的电子和磁特性。在Mn-Bi/CrI3范德华异质结构中,半金属Mn-Bi可以通过电荷转移诱导CrI3的半金属丰度。与其他掺杂体系相比,Mn-Bi表现出最有利的磁性能。因此,Mn-Bi/CrI3异质结构为自旋电子器件的发展铺平了道路。
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引用次数: 2
Guest Editorial: Emerging Plasma Nanotechnologies 嘉宾评论:新兴等离子体纳米技术
IF 1.7 Q3 Engineering Pub Date : 2022-12-14 DOI: 10.1109/OJNANO.2022.3224346
Masaharu Shiratani;John P. Verboncoeur;Jong-Shinn Wu
The papers in this special section shed light on recent progresses on nanoscience and nanotechnology based on low pressure plasma and atmospheric plasma, whereas it also suggests directions for future research.
本专题的论文不仅介绍了纳米科学和基于低压等离子体和大气等离子体的纳米技术的最新进展,而且还提出了未来研究的方向。
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引用次数: 0
Recent Advances and Design Strategies Towards Wearable Near-Infrared Spectroscopy 可穿戴近红外光谱技术的最新进展与设计策略
IF 1.7 Q3 Engineering Pub Date : 2022-12-05 DOI: 10.1109/OJNANO.2022.3226603
Shuoyan Liu;Bing Xue;Wenyuan Yan;Alina Y. Rwei;Changsheng Wu
With a growing focus on properties of softness, miniaturization, and intelligence, extensive research has been focusing on constructing wearable electronic devices facilitating comfort, wearable health monitoring and diagnosis. Among recent progress in the development of wearable bioelectronics, wearable near-infrared spectroscopy (NIRS) devices demonstrate wide implementation possibilities in multiple health monitoring scenarios. Throughout the years, multiple design strategies have assisted in developing wearable NIRS devices with high wearing comfortability and miniaturized size. This review summarizes the principle of NIRS technology, recent advances in design strategies towards soft, wearable, miniaturized NIRS devices, and the future potential development directions. Based on the discussion of different design strategies, including modular device design, flexible hybrid electronics, and materials innovation, we also pinpoint some development directions for wearable NIRS. The reviewed and proposed research efforts may enhance the applicability and capability of NIRS as an important technology for digital health.
随着人们对软性、小型化和智能化的日益关注,人们对构建可穿戴电子设备进行了广泛的研究,以实现舒适、可穿戴的健康监测和诊断。在可穿戴生物电子学发展的最新进展中,可穿戴近红外光谱(NIRS)设备在多种健康监测场景中展示了广泛的实施可能性。多年来,多种设计策略有助于开发具有高穿着舒适性和小型化尺寸的可穿戴近红外装置。本文综述了近红外光谱技术的原理、近红外光谱器件软性、可穿戴性、小型化设计策略的最新进展以及未来潜在的发展方向。基于对不同设计策略的讨论,包括模块化器件设计、柔性混合电子和材料创新,我们也指出了可穿戴近红外光谱的一些发展方向。综述和建议的研究工作可以提高近红外光谱作为数字健康重要技术的适用性和能力。
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引用次数: 1
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IEEE Open Journal of Nanotechnology
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