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Efficacy of Empagliflozin Therapy in Patient with Acute Heart Failure: Meta-analysis 恩格列净治疗急性心力衰竭的疗效:meta分析
Pub Date : 2023-10-25 DOI: 10.29303/jppipa.v9i10.5000
Yusra Pintaningrum, Komang Pranayoga
Heart failure is still a common disorder with a high morbidity and mortality rate around the world. New drugs sodium-glucose cotransporter 2 inhibitors (SGLT2i) such as empagliflozin are currently showing promising results across the HF spectrum. Based on this, the authors are interested in researching the efficacy of Empaglifozin Therapy in Patient with Acute Heart Failure. This study used a systematic search using PRISMA principle in several online databases (Pubmed, Cochrane library and Google scholar). The selected study was an RCT or clinical trial with a population of Acute HF patients. The intervention group is Empagliflozin in any dose compared to placebo. The primary outcome for this meta-analysis is the levels of BNP or NT-proBNP and mortality after intervention. Selected study will be assessed and analyzed using Review Manager software version 5.3 with 95% CI. The two studies selected in this meta-analysis had a total sample size of 290 in the intervention group and 285 in the placebo group. Heterogenecity test obtained [p=0.44; I2 0%], indicating the homogenous data and the study is recommended to use the fixed effect method. The pooled effect size of RR is 0.472 [CI95% 0.24-0.75, P=0.003], meaning that there is a significant favorable outcome in empagliflozin group than in the placebo group. The results showed that empagliflozin had shown a favorable effect in reduction of the risk of death and reducing level of NT-proBNP in patient with acute heart failure.
心力衰竭仍然是一种常见的疾病,在世界范围内具有很高的发病率和死亡率。新型药物钠-葡萄糖共转运蛋白2抑制剂(SGLT2i),如恩格列净,目前在HF谱上显示出有希望的结果。基于此,笔者对恩帕列净治疗急性心力衰竭的疗效进行了研究。本研究采用PRISMA原则对多个在线数据库(Pubmed、Cochrane library和Google scholar)进行系统检索。所选的研究是一项随机对照试验或临床试验,涉及急性心衰患者。干预组是任何剂量的恩帕列净与安慰剂相比。本荟萃分析的主要结局是干预后BNP或NT-proBNP水平和死亡率。选定的研究将使用Review Manager软件5.3版本进行评估和分析,95% CI。本荟萃分析中选择的两项研究的总样本量为干预组290例,安慰剂组285例。异质性检验得到[p=0.44;[2 0%],表明本研究数据同质,建议采用固定效应法。合并效应大小RR为0.472 [CI95% 0.24-0.75, P=0.003],说明恩格列净组预后明显优于安慰剂组。结果显示,恩格列净在降低急性心力衰竭患者的死亡风险和降低NT-proBNP水平方面有良好的效果。
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引用次数: 0
Analysis of Item Characteristics of Natural Sciences National Examinations for Junior High School Based on the Classical Test Theory Approach 基于经典测试理论方法的初中自然科学全国统考试题特征分析
Pub Date : 2023-10-25 DOI: 10.29303/jppipa.v9i10.3698
Mariana Mariana, Djaffar Lessy, Dinar Riaddin, Muhammad Rizal Hardiansyah, Corneli Pary
This study aims to analyze the characteristics of the items based on the classical test theory approach. This research is exploratory research with a quantitative approach. The data used in this study were data from the 2015 Science Subject National Examination for Junior High School in Daerah Istimewa Yogyakarta (DIY) province. The samples taken in this study were 9054 students. Test takers are grouped into high groups and low groups based on the total score obtained. Estimation of item parameters using Excel and QUEST. The results of the analysis show that based on the classical test theory approach, the average item difficulty level ) in the high group is in the easy category, while in the low group, it is in the medium category, the average item differential index ( ) shows that the test ability to distinguish students with high abilities and low abilities in both the high and low groups is in the unfavorable category; and the reliability coefficient of the test (ρ) in the high group has high reliability, and the low group has perfect reliability
本研究旨在基于经典测试理论的方法分析项目的特征。本研究是一种定量的探索性研究。本研究使用的数据来自2015年日惹Daerah Istimewa (DIY)省初中科学科目全国考试数据。本研究的样本为9054名学生。考生根据总分分为高组和低组。使用Excel和QUEST进行项目参数估计。分析结果表明:基于经典测试理论方法,高组的平均题难程度()处于易类,低组的平均题难程度()处于中类,平均题难程度指数()表明,高、低组区分高、低能力学生的测试能力均处于不利类;且试验的信度系数(ρ)在高组具有高信度,低组具有完全信度
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引用次数: 0
Food Bank Operation and Perceptions of Recipients on Food Surplus Redistribution in North and South Jakarta 雅加达北部和南部粮食银行的运作和接受者对粮食剩余再分配的看法
Pub Date : 2023-10-25 DOI: 10.29303/jppipa.v9i10.4415
Khairunisa Khairunisa, Sri Setiawati, Saptarining Wulan
Food waste is one of the highest sources of waste in Indonesia. This condition is contrary to food insecurity in Indonesia, which ranks third highest in Southeast Asia. Food waste generation reduction can be made by seeking management food surplus redistribution. Currently, the redistribution of food surplus began to be carried out to reduce food waste and food insecurity. This study aimed to determine the redistribution process of food surplus in North and South Jakarta from being collected to being sent to the recipient and the perceptions and acceptance attitudes of recipients of food surplus towards the redistribution of food they receive. The method used is using a Likert Scale and interviews. Based on the research results, there are 5 stages in surplus food management: collection and preparation, storage and inspection, delivery and receipt, documentation, and re-checking. Food surplus recipients have a good perception and acceptance of the redistribution of food surplus. However, some recipients still need to gain more knowledge about the expiration date and best-before, which affects the perception and management of food donations received. The recommended efforts include maintaining positive perceptions and attitudes of the recipient and people by developing education about food and waste management from food bank programs with support by the government institution which had same agenda and already cooperated with food bank.
食物垃圾是印尼最大的垃圾来源之一。这种情况与印尼的粮食不安全状况相反,印尼的粮食不安全状况在东南亚排名第三。减少食物浪费可以通过寻求管理粮食剩余再分配来实现。目前,已开始对剩余粮食进行再分配,以减少粮食浪费和粮食不安全。本研究旨在确定雅加达北部和南部的粮食剩余从收集到发送给接受者的再分配过程,以及粮食剩余接受者对其收到的粮食再分配的看法和接受态度。使用的方法是使用李克特量表和访谈。根据研究结果,剩余食品管理分为5个阶段:收集和准备、储存和检验、交付和接收、记录和复核。粮食剩余接受者对粮食剩余再分配有较好的认知和接受度。然而,一些受援者仍然需要了解更多关于过期日期和最佳食用日期的知识,这影响了对所收到的食品捐赠的认识和管理。建议的努力包括在政府机构的支持下,通过发展食物银行项目的食物和废物管理教育,保持接受者和人民的积极看法和态度,政府机构有相同的议程,并且已经与食物银行合作。
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引用次数: 0
Profil Kemampuan Berpikir Kreatif dan Komunikasi Ilmiah Siswa SMP pada Materi Teknologi Ramah Lingkungan 描述中学生在绿色技术材料上的创造性思维能力和科学交流
Pub Date : 2023-10-25 DOI: 10.29303/jppipa.v9i10.3884
Dine Nurdian, None Saefudin, None Amprasto
Kemampuan berpikir kreatif dan komunikasi ilmiah siswa sangat dibutuhkan. Kemampuan tersebut harus dimiliki oleh siswa agar siswa dapat bersaing secara sehat dan mampu menyelesaikan berbagai permasalahan yang semakin kompleks di abad 21. Adapun tujuan penelitian ini untuk mengetahui profil kemampuan berpikir kreatif dan komunikasi ilmiah siswa dalam pembelajaran teknologi ramah lingkungan. Metode yang digunakan dalam penelitian ini adalah deskriptif kuantitatif. Sampel penelitian terdiri atas 35 orang siswa, 16 laki-laki dan 19 perempuan. Instrumen yang digunakan berupa tes essay untuk materi teknologi ramah lingkungan. Adapun indikator yang digunakan dalam penelitian ini yaitu : 1) berpikir lancar ; 2) berpikir luwes; 3) berpikir orisinil; dan 4) kemampuan mengelaborasi. Indikator yang digunakan dalam penelitian ini yaitu indikator mempresentasikan pengetahuan. Dari hasil analisis data menunjukkan bahwa kemampuan berpikir kreatif siswa untuk kategori tinggi hanya 1 siswa (3%), kategori sedang 21 orang (60%), dan kategori sangat rendah 13 orang (37%). kemampuan komunikasi ilmiah siswa untuk indikator merepresentasikan untuk kategori sangat tinggi 4 siswa (11,4%), kategori tinggi 2 orang (5,7%), kategori sedang 10 siswa (28,6%), kategori rendah 2 orang (5,7%), dan kategori sangat rendah 17 orang (48,6%). Sehingga kemampuan berpikir kreatif dan komunikasi ilmiah siswa secara keseluruhan harus ditingkatkan.
学生的创造性思维能力和科学交流是必不可少的。这种能力必须是学生具备的,这样学生才能在21世纪进行健康的竞争,并能够解决日益复杂的问题。至于本研究的目的,是了解学生在绿色技术学习中具有创造性思维能力和科学交流能力的概况。本研究采用的方法是定量描述性的。该研究样本由35名学生、16名男性和19名女性组成。这是对环保技术材料的科学论文测试。至于本研究使用的指标是:1)流畅思考;2)灵活思维;3)原创思维;4)详细说明能力。本研究中使用的指标是知识的体现。数据分析表明,学生高层次思维能力只有一个学生(3%),21人(60%),非常低13人(37%)。学生的科学交流能力代表了四名学生(11.4%)、两名学生(5.7%)、10名学生(286%)、2名学生(286%)、2名学生(5.7%)和17名学生(48.6%)等类别。因此,学生整体的创造性思维和科学交流能力必须得到加强。
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引用次数: 0
The Effect of STEM Integrated Science Innovative Learning Model on Students' Critical Thinking Skills: A Meta-Analysis STEM综合科学创新学习模式对学生批判性思维能力的影响:meta分析
Pub Date : 2023-10-25 DOI: 10.29303/jppipa.v9i10.4390
Lidya Jasmi, Marjuni Marjuni, Nailul Rahmah Pohan, None Asrizal, Fatni Mufit
This research is a meta analysis. This study aim to analyze the effect of STEM integrated science innovative learning model on students' critical thinking skills. The data collection technique used is the literature review technique, namely by searching and collecting journal articles taken from Google Scholar. Data analysis used quantitative descriptive statistical analysis which aims to obtain effect size values. The results of this study indicate that: 1) The value of the effect size at the educational level, namely the elementary, junior high and high school levels, is in the very high category 2) The effect size value in the sciences, namely biology, physics, chemistry and integrated natural science, is in the very high category 3) The effect size value of the learning model used is inquiry, blended learning, problem based learning, and project based learning with very high categories.
这项研究是一个元分析。本研究旨在分析STEM综合科学创新学习模式对学生批判性思维能力的影响。使用的数据收集技术是文献综述技术,即通过检索和收集谷歌Scholar上的期刊文章。数据分析采用定量描述性统计分析,旨在获得效应大小值。本研究结果表明:1)小学、初中和高中教育层次的效应量值处于非常高的类别;2)生物、物理、化学和综合自然科学的效应量值处于非常高的类别;3)所使用的学习模式的效应量值是探究、混合学习、基于问题的学习和基于项目的学习,具有非常高的类别。
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引用次数: 0
Development of PBL-Based Sound Wave Interactive Multimedia Using Lumi for Class XI High School Students 利用Lumi开发基于pbl的高中11班声波交互多媒体
Pub Date : 2023-10-25 DOI: 10.29303/jppipa.v9i10.4426
Vebby Oksaviona, Nur Islami, Muhammad Nasir
This study aims to describe the development, feasibility, and practicality of PBL-based sound wave interactive multimedia using Lumi. The research method used is research and development. The model used is an Instructional Design type ADDIE which consists of 5 stages namely Analyze, Design, Development, Implementation, and Evaluate. The results showed that PBL-based sound wave interactive multimedia using Lumi was declared feasible by the validator with an average Aiken validity index of 0.86 (very high). The teacher as a practitioner states that practical interactive multimedia is used in learning physics with an average value of 93.30 (very practical). Students also stated that practical interactive multimedia was used in learning physics with an average value of 90.46 (very practical). Based on the results of the study, it can be concluded that PBL-based interactive multimedia using Lumi is declared feasible and practical for use in the physics learning process, especially in sound wave material.
本研究旨在描述利用Lumi实现基于pbl的声波交互多媒体的发展、可行性和实用性。使用的研究方法是研究和开发。使用的模型是一个教学设计型的ADDIE,它由5个阶段组成,即分析、设计、开发、实施和评估。结果表明,基于pbl的声波交互多媒体使用Lumi被验证者认为是可行的,平均Aiken效度指数为0.86(非常高)。教师作为实践者,在物理学习中使用了实践性交互式多媒体,平均分为93.30(非常实践性)。学生也表示在物理学习中使用了实用的交互式多媒体,平均得分为90.46(非常实用)。研究结果表明,基于pbl的交互式多媒体在物理学习过程中是可行的,特别是在声波材料中。
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引用次数: 0
Proximate Quality of Low-Sodium Salted Egg 低钠咸蛋的近似质量
Pub Date : 2023-10-25 DOI: 10.29303/jppipa.v9i10.5293
Hajar Setyaji, Metha Monica
This study aims to determine the use of low-sodium salt for the proximate quality of salted eggs. The research method used a complete randomized design with P0 control treatment, 10% P1 low sodium salt treatment, 20% P2 low sodium salt treatment, and 30% P3 low sodium salt treatment. Analysis data was carried out on the contents of water, protein, lipid, and ash content. The data were analyzed using SPSS with a significance level of 0.05. The results indicated that the water content of egg whites and egg yolks was not significantly different from the treatment of ordinary salt and low sodium salt treatment. The lipid content was also not significantly different at all treatments. Protein content, ordinary salt treatment, and low sodium salt provided a noticeable difference in egg white protein content (p<0.05). Making salted eggs using low-sodium salt produces salted eggs with the similar proximate quality as the control with the lower sodium levels than the control treatment.
本研究旨在确定低钠盐对咸蛋近似质量的影响。研究方法采用完全随机设计,采用P0对照处理、10% P1低钠盐处理、20% P2低钠盐处理、30% P3低钠盐处理。对其水分、蛋白质、脂肪和灰分含量进行了分析。数据采用SPSS统计分析,显著性水平为0.05。结果表明,蛋清和蛋黄的含水量与普通盐和低钠盐处理差异不显著。脂质含量在各处理间也无显著差异。蛋白质含量、普通盐处理和低钠盐处理的蛋清蛋白质含量差异显著(p < 0.05)。用低钠盐制作咸蛋,得到的咸蛋质量与对照差不多,但钠含量低于对照处理。
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引用次数: 0
Teacher’s and Student’s Perceptions of Green Chemistry and its Principles in Chemistry Learning in High Schools 高中化学学习中师生对绿色化学的认知及其原则
Pub Date : 2023-10-25 DOI: 10.29303/jppipa.v9i10.4756
Jusniar Jusniar, None Syamsidah, Army Auliah
Green Chemistry (GC) is an issue that is very relevant to chemistry subjects in senior high schools. Chemistry subject is closely related to the environment as one of the pillars of sustainable development. This certainly contributes to the possibility integration of green chemistry principles into chemistry learning. This exploratory research aims to describe the principles of GC that allow it to be integrated into chemistry learning in grades X and XI; describes the high school teacher's and students' perceptions and understanding of GC and its principles in chemistry learning. The subjects in this study were 230 students who were selected purposively from five Senior high schools. Totally 40 chemistry teachers were purposively used as research subjects from a number of high schools throughout South Sulawesi. The instrument used was ten items of teacher's perception questionnaires, while the students' perception questionnaire consisted of twelve items. Guidelines for interviewing teachers and students were used to describe more deeply about their understanding of GC. All instruments have been validated by two experts. The results of the exploration of material elements for phases E and F show that five GC principles can be integrated into learning chemistry. In general, the teacher's perception of GC is good, which assumes that GC is an environmentally friendly concept. Understanding of the five principles of GC for students and teachers is in the moderate and poor categories. This shows the importance of integrating GC principles in the form of positive habits in chemistry learning.
绿色化学是一个与高中化学学科密切相关的课题。化学学科与环境密切相关,是可持续发展的支柱之一。这当然有助于将绿色化学原理整合到化学学习中。描述了高中教师和学生在化学学习中对GC及其原理的认知和理解。本研究的研究对象是有目的地从五所高中抽取的230名学生。共有40名化学教师被有意作为研究对象,他们来自南苏拉威西的一些高中。所使用的工具为教师知觉问卷的10项,学生知觉问卷的12项。我们使用了采访教师和学生的指南来更深入地描述他们对GC的理解。所有仪器都经过两位专家的验证。E相和F相物质元素的探索结果表明,五种GC原理可以整合到化学学习中。总的来说,老师对GC的认知是好的,他认为GC是一个环保的概念。学生和教师对GC五原则的理解处于中等和较差的类别。这显示了在化学学习中以积极习惯的形式整合GC原则的重要性。
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引用次数: 0
Implementation of Electronic Module Based Multiple Representation on Buffer Solution Materials to Improve Students’ Self-Regulated Learning and Cognitive Learning Outcomes 基于电子模块的缓冲解材料多重表示的实现,提高学生自主学习和认知学习效果
Pub Date : 2023-10-25 DOI: 10.29303/jppipa.v9i10.3656
Irfan Kamaludin Syam, Isana Supiah Yosephine Louise
This research aims to determine the differences between self-regulated learning (SRL) and cognitive learning outcomes (CLO) of students who use multiple representation-based e-modules with students who use other teaching materials without being based on multiple representations on buffer solution materials and to determine the percentage of effective contribution. The subjects of this study were students of class XI MIPA at one of the high schools in Yogyakarta. The sampling technique carried out is cluster random sampling with a quasi-experiment method by posttest-only control group design. The instruments used are questionnaires on self-regulated learning and cognitive learning outcomes. The data analysis technique used in the field test results used Hotelling's Trace test and the results of effective contribution were obtained from the Partial Eta Squared value. The results showed that the significance value of 0.000 < 0.05 so that H0 was rejected, which means that there are differences in SRL and CLO of students between students who use multiple representation-based e-modules and students who use other teaching materials without multiple representations based on buffer solution materials. The percentage of effective contribution of the use of e-modules to SRL by 16.5%, CLO by 11.8%, and SRL and CLO by 20.3%.
本研究旨在确定使用基于多个表征的电子模块的学生与使用其他教材而不使用缓冲解决方案材料的学生的自我调节学习(SRL)和认知学习结果(CLO)的差异,并确定有效贡献的百分比。抽样技术采用准实验整群随机抽样,采用后验对照组设计。使用的工具是自我调节学习和认知学习结果问卷。现场试验结果采用的数据分析技术为Hotelling’s Trace检验,有效贡献结果由偏Eta平方值得到。结果表明,显著性值为0.000 <0.05,使得H0被拒绝,这意味着使用基于多个表征的电子模块的学生与使用其他没有基于缓冲溶液材料的多个表征的教材的学生在SRL和CLO上存在差异。电子组件的使用对SRL的有效贡献百分比为16.5%,CLO为11.8%,SRL和CLO为20.3%。
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引用次数: 0
Implementation of Visual and Intellectual Auditory Somatic Learning Model to Improving Christian Religious Education Learning Outcomes 运用视智听觉躯体学习模式提高基督教宗教教育学习成果
Pub Date : 2023-10-25 DOI: 10.29303/jppipa.v9i10.4989
Lasino Lasino, Novi Sitri Harisa, Meilanda Kristanti Ndiling
The SAVI learning model is still rarely known and used in learning at both the elementary, junior high and high school levels. Because this learning model as a whole maximizes the use of the senses of each existing student. Therefore, it is necessary to have a teacher who teaches with joy, activeness and creativity in managing the class in terms of combining the models, methods and learning media used. The thing that is a problem at Hasael Puru Vocational School besides inadequate facilities and infrastructure is the monotonous teaching and learning model of PAK teachers, namely only using the lecture method when teaching makes students become bored and sleepy in class so that it has an impact on decreasing student learning outcomes. This research was conducted to find out whether there was an increase in the learning outcomes of PAK Hasaek Vocational Students when the SAVI learning model was implemented. This study uses quantitative research that is a descriptive survey, with 25 student respondents who were given questionnaires totaling 30 questions (Variable X 15 questions and Variable Y 15 questions) and also took the results of students' summative scores for comparison, namely the summative scores of the even semester of the school year 2021/2022 and summative grades for the odd semester of the 2022/2023 academic year. With the research results it was found that when the SAVI learning model was implemented, student learning outcomes increased.
SAVI学习模式在小学、初中和高中阶段的学习中仍然很少为人所知和使用。因为这种学习模式作为一个整体最大限度地利用了每个现有学生的感官。因此,结合教学模式、教学方法和学习媒介,在课堂管理中需要一位寓教于乐、积极主动、富有创造性的教师。Hasael Puru Vocational School的问题除了设施和基础设施不足外,还有PAK教师的教学模式单一,即教学使学生在课堂上感到无聊和困倦,只使用讲课的方法,从而降低了学生的学习效果。本研究旨在了解实施SAVI学习模式后,PAK Hasaek职校学生的学习成果是否有所提高。本研究采用定量研究的方法,即描述性调查,对25名学生进行问卷调查,共30个问题(变量X 15个问题,变量Y 15个问题),并将学生的总结成绩进行比较,即2021/2022学年双数学期的总结成绩和2022/2023学年双数学期的总结成绩。研究结果发现,实施SAVI学习模式后,学生的学习成果有所提高。
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引用次数: 0
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