This randomized controlled trial investigated the effectiveness of an affect-adjusted, supervised, multimodal, online, and home-based exercise group protocol as an adjunct therapy to antidepressants on depressive symptoms, cardiorespiratory fitness, and side effects related to antidepressants in adults with major depression (MDD, diagnosed by a clinician). Depressive symptom scales were administered by a psychiatrist and self-reported. A health-related measure (i.e., cardiorespiratory fitness), was also administered. The exercise intervention was adjusted by perceived effort and affect (pleasure and enjoyment) toward exercise and lasted 12 weeks. In total, 59 adults with MDD were divided into two groups: the exercise-group (EG; exercise + pharmacotherapy) with 26-patients (76.9 % females, mean age 28.5 years) and the control-group (CG, pharmacotherapy) with 33-patients (78.7 % females, mean age 25.6 years). The EG had a lower dropout rate (15.3 %) than CG and an increase in cardiorespiratory fitness (CRF), which was not observed in the CG. Both groups showed a decrease in self-reported depressive symptoms. However, the EG had significantly lower depressive symptom scores at t1 and t2. The EG also had higher remission rates (t1, EG: = 42.3 % and CG = 27.2 %) and remission rates (t2, EG: = 72.7 % and CG = 48.1 %) than CG, which were maintained during the four month follow-up. Side effects from anti-depressant medication were larger in the EG compared to CG. Complementing usual care for MDD with exercise resulted in better clinical outcomes and supports the use of this type of exercise protocol in the clinical management of depression.
Identifying connections between various aspects of physical performance, motor skills, and cognitive abilities with the brain connectivity networks is essential for determining important brain regions associated with soccer performance. This study aimed to carry out the relationship between soccer-specific parameters and resting-state functional connectivity in soccer players.
Twenty-five soccer players (Vo2max; 50.68 ± 3.76 ml/min/kg) were participated voluntarily. The study encompassed a comprehensive assessment, including measures of physical performance, skill performance, and executive function (design fluency). Each participants underwent resting-state functional magnetic resonance imaging (fMRI) also allowing for the acquisition of data. The Linear regression were conducted between sport-specific parameters and functional connectivity values.
Our findings revealed a significant positive correlation between agility and linear sprinting with the dorsal attention network (DAN). Conversely, the aerobic fitness parameter demonstrated exhibited a significant negative correlation with the DMN. Skill performance (speed dribbling, passing, shooting) displayed a significant positive correlation with both sensorimotor network (SMN), and DAN. Moreover, design fluency test displayed a significant positive correlation with the DMN. Notably, IPSL and IPSR nodes within the DAN consistently demonstrated the highest degree of centrality across various sports parameters.
This study provides valuable insights into the intricate relationship among physical performance, skill proficiency, and executive function, as they relate to the functional connectivity of specific neural networks in soccer players. The outcomes establish a foundational understanding for future exploration and potential applications in sports science, and cognitive neuroscience in order to improve soccer performance.