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Quality of YouTube Videos Regarding Anterior Cruciate Ligament Reconstruction Using Quadriceps Tendon Autograft Is Unsatisfactory YouTubeTM 上有关使用股四头肌腱自体移植物进行前交叉韧带重建的视频质量并不令人满意。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-08-01 DOI: 10.1016/j.arthro.2024.01.002

Purpose

To assess the validity and informational value of teaching material regarding anterior cruciate ligament reconstruction (ACLR) using quadriceps tendon (QT) autograft provided on the YouTube video platform.

Methods

An extensive systematic search of the YouTube video platform was performed, and all videos that met the criteria were included in the analysis. The analysis of the video content was performed using the DISCERN instrument, Journal of American Medical Association (JAMA) benchmark criteria, and Global Quality Score (GQS). The duration of the videos, the date of publication, and the number of likes and views were recorded. Furthermore, videos were categorized based on the source (physicians, companies, patients), the subject (surgical technique, patient experience and overview [overview videos were videos in which multiple aspects were analyzed]), and the type of content (educational or subjective patient experience).

Results

A total of 88 videos were included in the analysis. Seventy-one (80.7%) videos were published by physicians, 15 (17.0%) by patients, and 2 (2.3%) by companies. The majority of the videos described various surgical techniques (59%-67.0%), 80.7% of the videos (72%-81.8%) had an educational nature, and the remaining 18.2% described patient experiences. The mean length of the videos was 8.21 ± 7.88 minutes. The mean number of views was 3,988.51 ± 9,792.98 (range 9-56,047), whereas the mean numbers of comments and likes were 30.07 ± 70.07 (range 0-493) and 4.48 ± 14.22 (range 0-82), respectively. The mean DISCERN score, JAMA score, and GQS were 27.43 ±11.56 (95% confidence interval [CI] 25.01-29.85; range: 17-68), 1.22 ± 0.85 (95% CI 1.04-1.40; range 0-3), and 1.82 ± 0.93 (95% CI 1.63-2.01; range 1-4), respectively. For all scores, videos published by physicians had greater quality (DISCERN score, JAMA score, and GQS) (P < .05). Among all of the analyzed videos, overview videos were of the highest quality (P < .05).

Conclusions

YouTube is a fast and open-access source of mass information. The overall quality of the videos on ACLR performed using QT autograft was unsatisfactory, demonstrating low educational quality and reliability. Currently, YouTube cannot be recommended as a reliable source of information on ACLR with the QT.

Clinical Relevance

Surgeons treating anterior cruciate ligament injuries should take special care when suggesting outside sources for patients to use to further educate themselves about this procedure. Due to the poor quality of the content, orthopaedic health care professionals should alert patients about the inaccuracies of YouTube videos addressing anterior cruciate ligament reconstruction with the quadriceps tendon. Additionally, health care practitioners should attempt to offer patients better options.

目的 本研究旨在评估 YouTubeTM 视频平台上提供的有关使用股四头肌腱(QT)自体移植物进行前交叉韧带重建(ACL-R)的教学材料的有效性和信息价值。方法 对 YouTubeTM 视频平台进行了广泛的系统搜索,并将所有符合标准的视频纳入分析。使用 DISCERN 工具、《美国医学会杂志》(JAMA)基准标准和全球质量评分(GQS)对视频内容进行分析。视频的持续时间、发布日期、点赞数和观看数都被记录了下来。此外,还根据视频来源(医生、公司、患者)、主题(手术技术、患者体验和概述[概述视频是对多个方面进行分析的视频])和内容类型(教育性或患者主观体验)对视频进行了分类。71部(80.7%)视频由医生发布,15部(17.0%)由患者发布,2部(2.3%)由公司发布。大部分视频描述了各种手术技术(59 - 67.0%),80.7%的视频(72 - 81.8%)具有教育性质,其余 18.2%的视频描述了患者的经历。视频的平均长度为 8.21 ± 7.88 分钟。平均观看次数为(3988.51±9792.98)次(范围:9-56047),平均评论数和点赞数分别为(30.07±70.07)次(范围:0-493)和(4.48±14.22)次(范围:0-82)。DISCERN评分、JAMA评分和GQS的平均值分别为27.43±11.56(95% CI:25.01-29.85;范围:17-68)、1.22±0.85(95% CI:1.04-1.40;范围:0-3)和1.82±0.93(95% CI:1.63-2.01;范围:1-4)。在所有评分中,医生发布的视频质量更高(DISCERN 评分、JAMA 评分和 GQS)(p<0.05)。在所有分析过的视频中,概述视频的质量最高(p<0.05)。使用 QT 自体移植物进行前交叉韧带重建的视频总体质量不尽人意,显示出教育质量和可靠性较低。目前,YouTube™ 还不能被推荐为使用股四头肌腱进行前交叉韧带重建的可靠信息来源。
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引用次数: 0
High Case Volume Predicts Greater Odds of Autograft Use and Meniscal Repair for Anterior Cruciate Ligament Reconstruction 高病例量预示着在前交叉韧带重建中使用自体移植物和半月板修复的几率更大。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-08-01 DOI: 10.1016/j.arthro.2020.08.011

Purpose

To evaluate how both annual surgeon and facility volume affect the cost and outcomes of anterior cruciate ligament reconstruction surgery. We also aimed to identify trends in how surgeon caseload predicts graft selection.

Methods

The 2014 State Ambulatory and Surgical Database from Florida was used. Every case with Current Procedural Terminology code 29888 (“Arthroscopic anterior cruciate ligament reconstruction”) was selected. Surgeon and facility identifiers were used to separate high- and low-volume groups, defined as >25 cases for surgeons and >125 cases for facilities. Univariate analysis was performed for patient demographics and surgical characteristics. Multivariate analysis was performed on significant factors to determine how these variables impact cost and odds of allograft usage, postoperative admission, and meniscal repair.

Results

There were 7905 cases performed between January 1, 2014, and December 31, 2014 after excluding same-year revisions. High-volume surgeons had $6155 lower total charges, were 1.949 times more likely to use an autograft, and had 54.5% lower odds of postoperative admission (all P < .001). They were also 1.196 times more likely to perform a meniscal repair (P = .017). In patients younger than 18, low-volume surgeons were 3.7 times more likely to use an allograft (P < .001). Concomitant multiligamentous procedures were also performed at greater rates in the high-volume group. Postoperative admission added $18,698, and allografts added $9174 (both P < .001).

Conclusions

We found that high-volume surgeons were more likely to perform a meniscal repair and less likely to have their patients admitted postoperatively, which was the second largest cost driver of anterior cruciate ligament reconstruction. They were also significantly less likely to use an allograft, especially in patients younger than the age of 18 years. High-volume surgeons had lower costs despite greater rates of concomitant procedures.

Level of Evidence

III, retrospective cohort study.

目的:评估外科医生和医疗机构的年手术量如何影响前交叉韧带重建手术的成本和效果。我们还旨在确定外科医生工作量如何预测移植物选择的趋势:方法: 我们使用了佛罗里达州 2014 年门诊和手术数据库。方法:我们使用了佛罗里达州 2014 年门诊和手术数据库,选取了每一个当前程序术语代码为 29888("关节镜下前交叉韧带重建")的病例。外科医生和医疗机构的标识符被用来区分高容量组和低容量组,外科医生的定义是大于 25 个病例,医疗机构的定义是大于 125 个病例。对患者人口统计学特征和手术特征进行了单变量分析。对重要因素进行了多变量分析,以确定这些变量如何影响成本以及使用同种异体移植、术后入院和半月板修复的几率:结果:2014年1月1日至2014年12月31日期间共进行了7905例手术,不包括同年的翻修手术。工作量大的外科医生总费用低6155美元,使用自体移植物的可能性高1.949倍,术后入院的几率低54.5%(P均<0.001)。他们进行半月板修复的可能性也高出1.196倍(P = .017)。在18岁以下的患者中,使用同种异体移植的几率是低量外科医生的3.7倍(P < .001)。同时进行的多韧带手术在高手术量组中的比例也更高。术后入院增加了18,698美元,异体移植增加了9174美元(均P < .001):我们发现,手术量大的外科医生更有可能进行半月板修复,也更不可能让患者术后入院,而这是前交叉韧带重建的第二大成本驱动因素。此外,他们使用同种异体移植的几率也明显较低,尤其是年龄小于18岁的患者。尽管同时进行手术的比例较高,但量大的外科医生的成本较低:III,回顾性队列研究。
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引用次数: 0
Editorial Commentary: Tranexamic Acid Shown to Not Inhibit Healing Following Rotator Cuff Repair in Rats 氨甲环酸不会抑制大鼠肩袖修复后的愈合
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-08-01 DOI: 10.1016/j.arthro.2024.02.025

As use of tranexamic acid (TXA) to decrease operative bleeding has increased during various orthopaedic surgical procedures, there has been corresponding increased interest regarding additional potential benefits—and also potential risks—of its use. By lessening bleeding during and shortly after arthroscopic surgery, some potential benefits include less postoperative pain, less hemarthrosis, and subsequent decreased formation of scar adhesions, resulting in less permanent stiffness. However, use of this pharmacologic agent also raises the possibility of negative effects upon tissue healing. In a rat rotator cuff repair model, no lasting significant benefit was associated with TXA administration, including no long-term decreased adhesions or stiffness. On the other hand, no adverse effects regarding healing were noted with TXA.

随着在各种骨科手术过程中使用氨甲环酸(TXA)来减少手术出血的情况越来越多,人们对其使用的其他潜在益处和潜在风险的兴趣也相应增加。通过减少关节镜手术期间和术后不久的出血,一些潜在的益处包括减轻术后疼痛、减少血栓形成以及减少疤痕粘连的形成,从而减轻永久性僵硬。不过,使用这种药剂也有可能对组织愈合产生负面影响。在大鼠肩袖修复模型中,使用 TXA 并没有带来持久的显著益处,包括粘连或僵硬程度没有长期减轻。另一方面,TXA 对愈合也没有不良影响。
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引用次数: 0
Cover Image & Video Link 封面图片和视频链接
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-08-01 DOI: 10.1016/S0749-8063(24)00424-9
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引用次数: 0
Athletes Continue to Show Functional Performance Deficits at Return to Sport After Anterior Cruciate Ligament Reconstruction: A Systematic Review 前交叉韧带重建后运动员恢复运动时的功能表现:系统回顾
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-08-01 DOI: 10.1016/j.arthro.2023.12.033

Purpose

To systematically review the existing literature on the functional performance of athletes at the time of return-to-sport (RTS) clearance after anterior cruciate ligament reconstruction (ACLR).

Methods

A systematic literature search of the MEDLINE, EMBASE, Scopus, and Web of Science databases was performed. The inclusion criteria were original research reports with study populations of athletes who had undergone ACLR and had undergone objective functional testing immediately after clearance to RTS. Functional testing was stratified by hop tests, strength tests, kinetic assessment, and kinematic assessment, and data were extracted from each study using a standardized template.

Results

Of the 937 unique studies identified, 46 met the inclusion criteria. The average time between ACLR and functional testing was 7.9 months among the included studies. In 10 of 17 studies, patients were found to have an average quadriceps strength limb symmetry index of less than 90%. However, only 2 of 12 studies found the average hop test limb symmetry index to be less than 90%. Kinematics included reduced knee flexion angle and increased trunk flexion on landing in ACLR patients compared with matched controls. On evaluation of kinetics, ACLR patients showed reduced peak vertical ground reaction force, lower peak knee extension and knee flexion moments, and altered energy absorption contribution compared with matched controls.

Conclusions

This systematic review suggests that athletes show functional deficits at the time of RTS at an average of 7.9 months after ACLR. Traditional functional tests, such as strength and hop tests, are not able to accurately identify patients who continue to show deficits. The most common biomechanical deficits that persist after RTS clearance include diminished peak knee extension moment, decreased knee flexion angle, increased trunk flexion angle, reduced vertical ground reaction force, and increased hamstring central activation ratio during various functional gait and landing tasks.

Level of Evidence

Level III, systematic review of Level I to III studies.

目的:系统回顾现有文献中关于前交叉韧带重建(ACLR)后运动员恢复运动(RTS)时的功能表现:在 MEDLINE、EMBASE、Scopus 和 Web of Science 中进行了系统的文献检索。纳入标准为原始研究报告,研究对象为接受过 ACLR 的运动员,并且在恢复 RTS 后立即进行了客观的功能测试。功能测试按跳跃测试、力量测试、动力学评估和运动学评估进行分层,并使用标准化模板从每项研究中提取:结果:在确定的 937 项独特研究中,有 46 项研究符合纳入标准。在纳入的研究中,前交叉韧带重建与功能测试之间的平均间隔时间为 7.9 个月。17项研究中有10项发现患者的平均股四头肌力量(QS)肢体对称指数(LSI)低于90%。然而,在 12 项研究中,只有两项研究发现跳跃测试的平均 LSI 低于 90%。与匹配的对照组相比,前交叉韧带损伤患者的运动学特征包括着地时膝关节屈曲角度减小和躯干屈曲增加。在运动学评估中,与匹配对照组相比,前交叉韧带损伤患者的垂直地面反作用力(vGFR)峰值降低,膝关节伸展和膝关节屈曲力矩峰值降低,能量吸收贡献发生变化:本系统综述表明,运动员在前交叉韧带重建后平均 7.9 个月恢复运动时会出现功能障碍。传统的功能测试,如力量和跳跃测试,并不能准确识别继续表现出功能缺陷的患者。RTS 清除后持续存在的最常见生物力学缺陷包括:在各种功能性步态和着地任务中,膝关节伸展力矩峰值减小、膝关节屈曲角度减小、躯干屈曲角度增大、垂直地面反作用力减小以及腿肌中心激活率增大。
{"title":"Athletes Continue to Show Functional Performance Deficits at Return to Sport After Anterior Cruciate Ligament Reconstruction: A Systematic Review","authors":"","doi":"10.1016/j.arthro.2023.12.033","DOIUrl":"10.1016/j.arthro.2023.12.033","url":null,"abstract":"<div><h3>Purpose</h3><p>To systematically review the existing literature on the functional performance of athletes at the time of return-to-sport (RTS) clearance after anterior cruciate ligament reconstruction (ACLR).</p></div><div><h3>Methods</h3><p><span>A systematic literature search of the MEDLINE, EMBASE, Scopus, and Web of Science databases was performed. The inclusion criteria were original research reports with study populations of athletes who had undergone ACLR and had undergone objective functional testing immediately after clearance to RTS. Functional testing was stratified by hop tests, strength tests, kinetic assessment, and kinematic assessment, and data were extracted from each study using a standardized </span>template.</p></div><div><h3>Results</h3><p>Of the 937 unique studies identified, 46 met the inclusion criteria. The average time between ACLR and functional testing was 7.9 months among the included studies. In 10 of 17 studies, patients were found to have an average quadriceps strength limb symmetry index of less than 90%. However, only 2 of 12 studies found the average hop test limb symmetry index to be less than 90%. Kinematics included reduced knee flexion angle and increased trunk flexion on landing in ACLR patients compared with matched controls. On evaluation of kinetics, ACLR patients showed reduced peak vertical ground reaction force, lower peak knee extension and knee flexion moments, and altered energy absorption contribution compared with matched controls.</p></div><div><h3>Conclusions</h3><p>This systematic review suggests that athletes show functional deficits at the time of RTS at an average of 7.9 months after ACLR. Traditional functional tests, such as strength and hop tests, are not able to accurately identify patients who continue to show deficits. The most common biomechanical deficits that persist after RTS clearance include diminished peak knee extension moment, decreased knee flexion angle, increased trunk flexion angle, reduced vertical ground reaction force, and increased hamstring central activation ratio during various functional gait and landing tasks.</p></div><div><h3>Level of Evidence</h3><p>Level III, systematic review of Level I to III studies.</p></div>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139467462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Commentary: Endoscopic Repair of Abductor Tendon Tears Results in Variable Patient Reported Outcomes and Generally Good to Excellent Results 内窥镜修复内收肌腱撕裂术的患者报告结果各异,但总体效果良好至卓越。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-08-01 DOI: 10.1016/j.arthro.2024.02.028

Abductor tendon pathology is fairly common, with up to a 25% incidence in patients having total hip arthroplasty and 30% having hip arthroscopy. A systematic review of endoscopic abductor tendon repair demonstrated that as few as 41% of patients with endoscopic repair of abductor tendon tears achieve a patient acceptable satisfactory state, but a major limitation of systematic reviews is extreme heterogeneity between included studies. Surgical techniques and skills differ, as do tear severity and confounding pathology such as labral tears. Another limitation is a focus on patient-reported outcome measures (PROMs). PROMs are important (we prefer happy patients with poor healing to unhappy patients with healed repairs), but PROMs are also “subjective,” and different cohorts of patients in different studies from different locations may have different perceptions or goals with regard to pain and function. As surgeons, we are able to observe gait, strength, and, with advanced imaging when indicated or for research purposes, healing. These, combined with PROMs, influence overall assessment of outcome. Experience and review of the literature show that endoscopic surgical repair of abductor tendon tears generally shows good or excellent results. If a patient has significant pain improvement and objectively improved gait, a calculation of an outcome threshold based on a subjective survey may not tell the full story.

内收肌腱病变相当常见,在接受全髋关节置换术和髋关节镜手术的患者中,内收肌腱病变发生率分别高达 25% 和 30%。一项关于内窥镜内收肌腱修复术的系统性综述显示,内窥镜内收肌腱撕裂修复术患者中只有41%能达到患者可接受的满意状态(PASS),但系统性综述的一个主要局限是所纳入研究之间存在极大的异质性。手术技术和技能各不相同,撕裂的严重程度和唇裂等混杂病理也不尽相同。另一个局限性是关注患者报告的结果指标(PROMs)。PROMs固然重要(我们更喜欢愈合不佳的满意患者,而不是愈合修复的不满意患者),但PROMs也是 "主观的",不同地点不同研究中的不同患者群体可能对疼痛和功能有不同的看法或目标。作为外科医生,我们能够观察步态、力量,并在必要时或出于研究目的使用先进的成像技术观察愈合情况。这些与 PROMs 结合起来,会影响对治疗结果的整体评估。经验和文献综述显示,内收肌腱撕裂的内窥镜手术修复一般都能取得良好或卓越的效果。如果患者的疼痛有明显改善,步态也有客观改善,那么根据主观调查来计算疗效阈值可能并不能说明全部问题。
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引用次数: 0
Location and Progression of Chondral Injuries at the Time of Revision Anterior Cruciate Ligament Surgery Varies by Sex 前交叉韧带翻修手术时软骨损伤的位置和进展因性别而异
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-08-01 DOI: 10.1016/j.arthro.2023.12.006

Purpose

To quantify progression of chondral and meniscal injuries between primary and revision anterior cruciate ligament (ACL) surgery.

Methods

Patients who underwent both index and revision ACL reconstruction between 2000 and 2020 at our institution were identified, and dates of injury and surgery, demographics, and clinical data were obtained from operative reports. Outerbridge grade was recorded in each compartment, along with presence and location of meniscal injury. The frequency of each injury between first and second cases was calculated. Differences in injury and progression were compared over time as well as between patient sex and age.

Results

The study included 189 patients (96 female, 93 male). Age at first surgery was 31.7 ± 13.2 years. Mean time to second injury was 3.3 ± 3.0 years. In total, 116 patients had a new or previous chondral injury (odds ratio, 1.6; 95% CI, 1.2-2.1). The medial femoral condyle (31%) and the patella (21%) accounted for the highest proportion of new injury to articular surfaces, whereas new injury to menisci was comparable between the medial (25%) and lateral (23%) meniscus. At the time of revision ACL reconstruction, females had a high prevalence of chondral injuries to the lateral compartment, whereas males had a high prevalence of chondral injury to the medial femoral condyle. The prevalence of new chondral injuries was comparable between sexes, with males having a slightly higher proportion. While time between surgeries, sex, and age had graphical evidence of moderating risk, the effects were small and imprecise.

Conclusions

Revision ACL reconstruction carried a 1.6 increase in the odds for new or progressive chondral lesions in our cohort. At the time of revision, females had a relatively higher proportion of lateral-sided chondral injuries, whereas males had a relatively higher proportion of medial femoral condyle injuries. The greatest increase in the prevalence of new and progressive lesions was observed in the medial femoral condyle and trochlea. This progression appeared to be moderated by time between surgeries, patient sex, and age; however, the differences were small and imprecise.

Level of Evidence

Level IV, therapeutic case series.

本研究的目的是量化初次前交叉韧带手术和翻修手术之间软骨和半月板损伤的进展情况。方法对 2000 年至 2020 年期间在我院接受初次和翻修前交叉韧带重建手术的患者进行鉴定,并从手术报告中获取受伤和手术日期、人口统计学和临床数据。记录了每个隔间的Outerbridge分级以及半月板损伤的存在和位置。计算了第一例和第二例之间每种损伤的发生频率。比较了不同时间段以及不同性别和年龄的患者在损伤和进展方面的差异。首次手术年龄为 31.7 ± 13.2 岁。第二次受伤的平均时间为(3.3 ± 3.0)年。共有116名患者有新的或之前的软骨损伤(OR= 1.6,95 CI:1.2 - 2.1)。股骨内侧髁(31%)和髌骨(21%)在关节面新损伤中所占比例最高,而半月板新损伤在半月板内侧(25%)和外侧(23%)之间不相上下。在进行前交叉韧带翻修术时,女性外侧室软骨损伤的发生率较高,而男性股骨内侧髁软骨损伤的发生率较高。新软骨损伤的发生率男女相当,男性略高。虽然手术间隔时间、性别和年龄在图形上有证据表明会降低风险,但影响很小且不精确。翻修时,女性外侧软骨损伤的比例相对较高,而男性股骨内侧髁损伤的比例相对较高。在股骨内侧髁和髁上观察到的新病变和进展性病变的发病率增幅最大。这种进展似乎受手术间隔时间、患者性别和年龄的影响而有所缓和,但差异很小且不精确。
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引用次数: 0
Tranexamic Acid Can Reduce Early Tendon Adhesions After Rotator Cuff Repair and Is Not Detrimental to Tendon-Bone Healing: A Comparative Animal Model Study 氨甲环酸可减少肩袖修复术后的早期肌腱粘连,且对肌腱-骨愈合无害:动物模型比较研究
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-08-01 DOI: 10.1016/j.arthro.2024.01.027

Purpose

To determine the effects of topical tranexamic acid (TXA) administration on tendon adhesions, shoulder range of motion (ROM), and tendon healing in an acute rotator cuff repair rat model.

Methods

A total of 20 Sprague Dawley rats were used. Tendon adhesion, ROM, and biomechanical and histological analysis of tendon-bone healing was conducted at 3 and 6 weeks after surgery. The rats underwent rotator cuff repair surgery on both shoulders and were administered TXA via subacromial injections. The tendon adhesion was evaluated macroscopically and histologically. Biomechanical tendon healing was measured using a universal testing machine, and histological analysis was quantified by H&E, Masson’s trichrome, and picrosirius red staining.

Results

At 3 weeks after surgery, the adhesion score was significantly lower in the TXA group (2.10 ± 0.32) than in the control group (2.70 ± 0.48) (P = .005), but there was no significant difference between the 2 groups at 6 weeks. Regarding ROM, compared with the control group, the TXA group showed significantly higher external rotation (36.35° ± 4.52° vs 28.42° ± 4.66°, P < .001) and internal rotation (45.35° ± 9.36° vs 38.94° ± 5.23°, P = .013) 3 weeks after surgery. However, at 6 weeks, there were no significant differences in external and internal rotation between the 2 groups. In the biomechanical analysis, no significant differences in gross examination (3 weeks, P = .175, 6 weeks, P = .295), load to failure (3 weeks, P = .117, 6 weeks, P = .295), or ultimate stress (3 weeks, P = .602, 6 weeks, P = .917) were noted between the 2 groups 3 and 6 weeks after surgery. In the histological analysis of tendon healing, no significant differences in the total score (3 weeks, P = .323, 6 weeks, P = .572) were found between the 2 groups 3 and 6 weeks after surgery.

Conclusions

Topical TXA administration showed a beneficial effect in reducing tendon adhesions and improving ROM 3 weeks postoperatively and had no effect at 6 weeks. This suggests that additional intervention with TXA may be useful in achieving long-term improvement in shoulder stiffness. Additionally, TXA may increase tissue ground substance accumulation in the late postoperative period but does not adversely affect tendon-bone interface healing.

Clinical Relevance

The use of TXA after rotator cuff repair has no effect on tendon-bone interface healing in clinical practice and can improve shoulder stiffness in the early postoperative period. Additional research on the long-term effects is needed.

目的 确定局部注射氨甲环酸(TXA)对急性肩袖(RC)修复大鼠模型中肌腱粘连、肩关节活动范围(ROM)和肌腱愈合的影响。方法:共使用了 20 只 Sprague-Dawley 大鼠,在术后三周和六周进行肌腱粘连、ROM 以及肌腱愈合的生物力学和组织学分析。大鼠接受了双肩肩袖修复手术,并通过肩峰下注射 TXA。对肌腱粘连进行了宏观和组织学评估。结果术后三周,TXA 组肌腱粘连评分(2.10 ± 0.32)明显低于对照组(2.70 ± 0.48,P = .005),但六周后两组间无明显差异。在ROM方面,术后三周,TXA组的外旋(TXA;36.35° ± 4.52°,对照组;28.42° ± 4.66°,P= 0.000)和内旋(TXA;45.35° ± 9.36°,对照组;38.94° ± 5.23°,P= 0.013)明显高于对照组。然而,在六周后,两组的外旋和内旋没有明显差异。在生物力学分析中,两组患者在术后三周和六周的大体检查(3周;P = .175,6周:P = .295)、负重至断裂(3周;P = .117,6周;P = .295)和极限应力(3周;P = .602,6周;P = .917)方面均无明显差异。在肌腱愈合的组织学分析中,两组术后三周和六周的总分(3 周;P = .323,6 周;P = .572)无明显差异。这表明,使用 TXA 进行额外干预可能有助于长期改善肩关节僵硬。临床意义在临床实践中,RC 修复术后使用 TXA 不会影响肌腱和骨界面的愈合,并能在术后早期改善肩部僵硬。关于长期效果,还需要进一步研究。
{"title":"Tranexamic Acid Can Reduce Early Tendon Adhesions After Rotator Cuff Repair and Is Not Detrimental to Tendon-Bone Healing: A Comparative Animal Model Study","authors":"","doi":"10.1016/j.arthro.2024.01.027","DOIUrl":"10.1016/j.arthro.2024.01.027","url":null,"abstract":"<div><h3>Purpose</h3><p>To determine the effects of topical tranexamic acid<span> (TXA) administration on tendon adhesions, shoulder range of motion (ROM), and tendon healing in an acute rotator cuff repair rat model.</span></p></div><div><h3>Methods</h3><p>A total of 20 Sprague Dawley rats<span> were used. Tendon adhesion, ROM, and biomechanical and histological analysis of tendon-bone healing was conducted at 3 and 6 weeks after surgery. The rats underwent rotator cuff repair surgery on both shoulders and were administered TXA via subacromial injections. The tendon adhesion was evaluated macroscopically and histologically. Biomechanical tendon healing was measured using a universal testing machine, and histological analysis was quantified by H&amp;E, Masson’s trichrome, and picrosirius red staining.</span></p></div><div><h3>Results</h3><p>At 3 weeks after surgery, the adhesion score was significantly lower in the TXA group (2.10 ± 0.32) than in the control group (2.70 ± 0.48) (<em>P</em> = .005), but there was no significant difference between the 2 groups at 6 weeks. Regarding ROM, compared with the control group, the TXA group showed significantly higher external rotation (36.35° ± 4.52° vs 28.42° ± 4.66°, <em>P</em> &lt; .001) and internal rotation (45.35° ± 9.36° vs 38.94° ± 5.23°, <em>P</em> = .013) 3 weeks after surgery. However, at 6 weeks, there were no significant differences in external and internal rotation between the 2 groups. In the biomechanical analysis, no significant differences in gross examination (3 weeks, <em>P</em> = .175, 6 weeks, <em>P</em> = .295), load to failure (3 weeks, <em>P</em> = .117, 6 weeks, <em>P</em> = .295), or ultimate stress (3 weeks, <em>P</em> = .602, 6 weeks, <em>P</em> = .917) were noted between the 2 groups 3 and 6 weeks after surgery. In the histological analysis of tendon healing, no significant differences in the total score (3 weeks, <em>P</em> = .323, 6 weeks, <em>P</em> = .572) were found between the 2 groups 3 and 6 weeks after surgery.</p></div><div><h3>Conclusions</h3><p>Topical TXA administration showed a beneficial effect in reducing tendon adhesions and improving ROM 3 weeks postoperatively and had no effect at 6 weeks. This suggests that additional intervention with TXA may be useful in achieving long-term improvement in shoulder stiffness. Additionally, TXA may increase tissue ground substance accumulation in the late postoperative period but does not adversely affect tendon-bone interface healing.</p></div><div><h3>Clinical Relevance</h3><p>The use of TXA after rotator cuff repair has no effect on tendon-bone interface healing in clinical practice and can improve shoulder stiffness in the early postoperative period. Additional research on the long-term effects is needed.</p></div>","PeriodicalId":55459,"journal":{"name":"Arthroscopy-The Journal of Arthroscopic and Related Surgery","volume":null,"pages":null},"PeriodicalIF":4.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139664736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disaggregation of Medical Research Data Reveals Outcome Differences in Demographic Groups and Presents Opportunity to Improve Patient Care 医学研究数据的分类揭示了人口群体的结果差异,为改善患者护理提供了机会。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-08-01 DOI: 10.1016/j.arthro.2024.04.020

Disaggregation, in the medical literature, means separation into demographic groups. This results in an opportunity to discover differences in outcomes by group, which could improve future treatments and provide outcome data, by group, that could be included in future systematic reviews. In research, the term disaggregation is most often used in reference to addressing inequities. We support the Sex and Gender Equity Research (SAGER) guidelines and encourage authors to examine how sex and gender are taken into account in their study and ensure adequate representation by sex and gender. (We respect that not all studies can or are designed to capture data by sex and gender, and that gender is “complex” and “fluid.”) Disaggregation is encouraged, when possible, for other demographic variables allowing evaluation of all marginalized (as well as nonmarginalized) populations, so that we can better care for patients.

在医学文献中,"分类 "是指按人口统计分组。这样就有机会发现不同群体在治疗结果上的差异,从而改进未来的治疗方法,并提供按群体划分的结果数据,以便纳入未来的系统综述中。在研究中,"分类 "一词最常用于解决不平等问题。我们支持 "性别与性别平等研究(SAGER)指南",并鼓励作者在研究中考虑性别与性别因素,并确保性别与性别的充分代表性。(我们认为,并非所有研究都能或在设计时都能按性 别和性别获取数据,而且性别是 "复杂 "和 "多变 "的)。在可能的情况下,我们鼓励对其他人口统计学变量进行分类,以便对所有边缘化(以及非边缘化)人群进行评估,从而更好地照顾病人。
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引用次数: 0
All-Inside Anterior Cruciate Ligament Reconstruction Had Clinical Outcome Similar to the Transtibial Technique Except for Improved Side-to-Side Difference and Tegner Activity Scale: A Systematic Review and Meta-analysis 全内侧前交叉韧带重建术的临床效果与经胫技术相似,但侧间差和Tegner活动量表有所改善:系统回顾与元分析》。
IF 4.4 1区 医学 Q1 ORTHOPEDICS Pub Date : 2024-08-01 DOI: 10.1016/j.arthro.2024.01.044

Purpose

To compare clinical outcomes of the all-inside technique with the transtibial technique in anterior cruciate ligament reconstruction based on available literature on this topic.

Methods

According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist, we conducted a systematic search for randomized controlled trials and cohort studies. Our comprehensive search encompassed PubMed, Embase, Cochrane Library, and Web of Science. We included randomized controlled trials (RCTs) and cohort studies that compared the 2 techniques with a minimal 1-year follow-up. Two independent authors assessed RCTs using the risk of bias tool developed by the Cochrane Collaboration and evaluated the quality of cohort studies using the Newcastle-Ottawa Scale for Assessing the Quality of Nonrandomized Comparative Trials. The subjective and objective outcomes, complications, and graft failure were obtained. R software was used to perform the analysis.

Results

The present analysis enrolled 9 RCTs (n = 687) and 11 cohort studies (n = 910). After a minimal 1-year follow-up in RCTs, functional outcomes such as International Knee Documentation Committee (IKDC) subjective score, Lysholm score, Tegner activity scale, Knee Society Score, and hop test were found to be similar between 2 techniques. The laxity outcomes, including the IKDC objective grade and pivot-shift test, were suggested to be comparable. There was a significant difference favoring the transtibial technique in terms of side-to-side difference (P = .04; 95% confidence interval [CI], 0.08-0.90). The pooled data from cohort studies indicated equivalent results in terms of IKDC subjective score, Lysholm score, side-to-side difference, IKDC objective grade, complications, and graft failure, with the exception of statistical difference in the Tegner activity scale (P = .03; 95% CI, –0.50 to –0.04).

Conclusions

Our findings suggest that there is no difference in most outcome scores between the all-inside and transtibial techniques for anterior cruciate ligament reconstruction. There are statistically significant differences in side-to-side difference and Tegner activity scale favoring the all-inside technique.

Level of Evidence

Level IV, meta-analysis of Level I to IV studies.

目的:根据现有相关文献,比较前交叉韧带重建中全内侧技术与经胫骨技术的临床效果:根据 PRISMA 核对表,我们对随机对照试验和队列研究进行了系统检索。我们的综合搜索包括 PubMed、Embase、Cochrane Library 和 Web of Science。我们纳入了对两种技术进行比较且随访至少一年的随机对照试验和队列研究。两位独立作者使用 Cochrane 协作组织开发的偏倚风险工具对 RCT 进行了评估,并使用纽卡斯尔-渥太华非随机比较试验质量评估量表对队列研究的质量进行了评估。获得了主观和客观结果、并发症和移植物失败。使用 R 软件进行分析:本分析共纳入了 9 项 RCT(n= 687)和 11 项队列研究(n= 910)。经过最短一年的RCT随访,发现两种技术的功能结果相似,如IKDC主观评分、Lysholm评分、Tegner活动量表、膝关节社会评分和Hop测试。而包括 IKDC 客观评分和枢轴移位测试在内的松弛结果则具有可比性。在侧对侧差异方面,经胫骨技术有明显优势(P=0.04,95% CI=0.08-0.90)。来自队列研究的汇总数据显示,IKDC主观评分、Lysholm评分、侧对侧差异、IKDC客观分级、并发症和移植物失败的结果相当,但Tegner活动量表有统计学差异(P=0.03,95% CI=-0.50至-0.04):我们的研究结果表明,在前交叉韧带重建术中,全内侧和经胫骨技术在大多数结果评分上没有差异。在侧对侧差异和 Tegner 活动量表中,全髂内侧技术的差异具有统计学意义。
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引用次数: 0
期刊
Arthroscopy-The Journal of Arthroscopic and Related Surgery
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