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2006 1st IEEE International Conference on Nano/Micro Engineered and Molecular Systems最新文献

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A New Type of Bio-Chemical Sensor Based on SPM 一种基于SPM的新型生化传感器
Huibin Zhao, Q. Ren, Yunsheng Lin, Yansheng Zuo, Li Han
A new type of bio-chemical sensor based on SPM was designed and fabricated in this paper. The bio-chemical sensor uses the SPM head as the probe part, which can convert the physical variation quantity on the micro-cantilever to electrical signals, and finally change it into image. In the experiment, the bio-chemical sensor based on SPM is used to detect two kinds of ssDNA molecules in PBS solution. By comparing the data in our experiment with that in other experiment, it can be seen that detecting unknown DNA molecules and other chemical or biological molecules in solution by this type of bio-chemical sensor is efficient and practical
本文设计并制作了一种基于SPM的新型生化传感器。生化传感器采用SPM头作为探头部分,将微悬臂梁上的物理变化量转化为电信号,最后转化为图像。在实验中,利用基于SPM的生化传感器检测PBS溶液中的两种ssDNA分子。通过对比我们的实验数据和其他实验数据可以看出,用这种生化传感器检测溶液中未知的DNA分子和其他化学或生物分子是高效和实用的
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引用次数: 0
Preparation and Damping Property of Polyurethane/vinyl Ester Resin IPNs and Gradient IPNs 聚氨酯/乙烯基酯树脂IPNs及梯度IPNs的制备及阻尼性能
D. Tang, Y. Qiao, L. Qiang, L. C. Zhao
A series of polyurethane/vinyl ester resin(PU/VER) simultaneous and gradient IPNs curing at room temperature are successfully synthesized by changing the component ratios of PU or VER in IPNs and casting the mixtures of different component ratios in a mold at various times. The dynamic mechanical analysis(DMA) detection results indicated that, the component ratios of IPNs have great effect to damping of simultaneous IPNs. The tandelta values of 70/30~90/10(wt.%) IPNs both are higher than 0.3 for a temperature range of nearly 80 degC. And the temperature ranges are further broadened by controlling the techniques of gradient IPNs by varying the time interval of coating and component sequence. The tandelta values of 70/30~80/20~90/10 gradient IPNs with 3.5h interval are higher than 0.3 for a temperature range of near 100 degC . This opens up broad possibilities for manufacture of promising noise and vibration damping materials by gradient techniques
通过改变聚氨酯/乙烯基酯树脂(PU/VER)在IPNs中的组分比,并在不同时间将不同组分比的混合物浇铸在模具中,成功地合成了一系列室温固化的聚氨酯/乙烯基酯树脂(PU/VER)同步和梯度IPNs。动态力学分析(DMA)检测结果表明,ipn的组成比对同步ipn的阻尼有很大影响。在近80℃的温度范围内,70/30~90/10(wt.%) IPNs的δ值均大于0.3。通过改变涂层时间间隔和组分顺序来控制梯度ipn技术,进一步拓宽了温度范围。在近100℃温度范围内,70/30~80/20~90/10梯度IPNs在间隔3.5h时的δ值均大于0.3。这为利用梯度技术制造有前途的噪声和振动阻尼材料开辟了广阔的可能性
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引用次数: 0
Uncertainties in the Micro/nano-Particles Induced Hyperthermia Treatment on Tumor Subject to External EM Field 微纳米粒子诱导热疗治疗外源电磁场下肿瘤的不确定性
Z. Deng, Jing Liu
Advancement of the recent micro/nano technology has stimulated the renaissance of using magnetic micro/nano particles embedded in biological tissues for the target tumor hyperthermia. As is well known, mathematical solutions of bioheat transfer involved in hyperthermia treatment are indispensable for computerized optimization of hyperthermia parameters. However, estimating the level of uncertainties associated with tissue temperature and thermal ablation area remains a major challenge. In this article, the uncertainties for the predicted temperatures of tissues due to approximate parameters were studied, based on numerical simulation of three-dimensional (3-D) quasi-steady state electromagnetic (EM) field and transient temperature response in biological tissues induced by the external EM field. Contributions of uncertainty from the tissue area permeated with micro/nano particles, the concentration and size of micro/nano particles, and the frequency and strength of the external alternating EM field were analyzed, and the uncertainty limits for temperature distributions in these cases were also estimated. The uncertainty analysis presented in this article is expected to serve as a significant guide for performing a highly efficient and also completely safe tumor hyperthermia using magnetic micro/nano particles.
近年来微纳米技术的进步刺激了磁性微纳米颗粒嵌入生物组织用于靶肿瘤热疗的复兴。众所周知,热疗过程中生物热传递的数学解对于热疗参数的计算机优化是必不可少的。然而,估计与组织温度和热消融面积相关的不确定性水平仍然是一个主要挑战。本文基于三维准稳态电磁场的数值模拟和外源电磁场对生物组织瞬态温度响应的数值模拟,研究了由于参数近似导致的组织温度预测的不确定性。分析了微纳粒子渗透的组织面积、微纳粒子的浓度和大小、外加交变电磁场的频率和强度对温度分布的不确定度贡献,并估计了这些情况下温度分布的不确定度限。本文提出的不确定性分析有望为使用磁性微/纳米颗粒进行高效且完全安全的肿瘤热疗提供重要指导。
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引用次数: 1
The Novel Fabrication Method and Optimum Tooling Design Used for Microlens Arrays 微透镜阵列的新型制造方法及优化工装设计
Yung-Kang Shen, Y. Shen
This paper reports a simple and novel procedure for mass production of microlens arrays. In this paper, a microlens array master is formed by room temperature imprint lithography and thermal reflow process. Next, electroforming is carried out to fabricate the metal mold insert from the microlens array master. Finally, micro-hot embossing is used to replicate microlens arrays. In this paper, a L9 experimental matrix design based on the Taguchi method is constructed to optimize the replication quality of molded microlens arrays. The results of the statistical analysis indicated that the processing temperature is the principal parameter affecting the sag height of the molded microlens array. The optimal processing parameters are processing temperature of 150degC, embossing pressure of 5.21MPa, processing time of 90s and de-molding temperature of 70degC. The 200times200 arrays of molded microlens, with a diameter of 150mum, a pitch of 200mum and a sag height of 31.51mum have been successfully fabricated. The average surface roughness of the molded microlens array is 4.31nm
本文报道了一种简单而新颖的微透镜阵列批量生产方法。本文采用室温压印和热回流法制备微透镜阵列母片。其次,通过电铸工艺从微透镜阵列母板上加工出金属模具镶件。最后,采用微热压印技术复制微透镜阵列。为了优化模制微透镜阵列的复制质量,构建了基于田口法的L9实验矩阵设计。统计分析结果表明,加工温度是影响模制微透镜阵列凹陷高度的主要参数。最佳工艺参数为加工温度150℃,压花压力5.21MPa,加工时间90℃,脱模温度70℃。成功制备了直径为150mm、节距为200mm、凹陷高度为31.51 mm的200 × 200微透镜阵列。模制微透镜阵列的平均表面粗糙度为4.31nm
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引用次数: 0
A New Packaging Method for Pressure Sensors by PDMS MEMS Technology 基于PDMS MEMS技术的压力传感器封装新方法
H.-H. Wang, P. Yang, W. Liao, L.-J. Yang
This paper proposes a novel wafer-level packaging (WLP) method at room temperature for piezoresistive pressure sensors. We use a polydimethylsiloxane (PDMS) sheet as a candidate for replacing a Pyrex glass wafer, to seal the backside V-grooved chambers of the pressure sensor chips. PDMS is a well-known material in MEMS technology recently. It is not only cheap but also has a merit of a simple process. We also fabricated piezoresistive pressure sensors, made by the same batch, with different packaging materials of Pyrex glass and PDMS sheet in the paper, respectively. The spin-coating approach is accessed to control the thickness of PDMS by applying the silicon and Teflon disks, as the supporting substrates during the formation of PDMS sheets. The sensors packaged by the PDMS room temperature bonding herein almost have the same performance as the ones packaged by the conventional anodic bonding through the real verification of pressure testing
提出了一种压阻式压力传感器在室温下的晶圆级封装方法。我们使用聚二甲基硅氧烷(PDMS)片材作为替代耐热玻璃晶圆的候选材料,以密封压力传感器芯片的背面v型槽腔。PDMS是近年来MEMS技术中备受关注的一种材料。它不仅价格便宜,而且工艺简单。我们还制作了同批次的压阻式压力传感器,分别采用Pyrex玻璃和PDMS片纸的不同包装材料。在PDMS片材形成过程中,利用硅和聚四氟乙烯盘作为支撑衬底,采用自旋涂覆的方法控制PDMS的厚度。通过压力测试的实际验证,本文采用PDMS室温键合封装的传感器与传统阳极键合封装的传感器性能基本相同
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引用次数: 5
PECVD SiC as a Chemical Resistant Material in MEMS PECVD SiC在MEMS中的耐化学性研究
Hui Guo, Y. Wang, Sheng-mei Chen, Guobing Zhang, Haixia Zhang, Zhihong Li
Silicon carbide (SiC) is a promising material for the device operating in hash environment, such as high temperature, high pressure or erodent environment, owning to its excellent electrical, mechanical, and chemical properties. The PECVD process allows deposition of SiC at low temperature (200degC-400degC), which makes SiC has better compatibility in Post-CMOS processes. In this paper, PECVD SiC has been investigated as a chemical resistant material in MEMS systematically. SiC was utilized as a coating layer to protect micromachined polysilicon devices from erosive environment and as a wet-etch mask to pattern silicon and glass. SiC was also used to construct microstructures taking the merit of SiC's chemical stability.
碳化硅(SiC)具有优异的电学、力学和化学性能,是在高温、高压或侵蚀等恶劣环境下工作的器件的理想材料。PECVD工艺允许SiC在低温(200℃-400℃)下沉积,这使得SiC在后cmos工艺中具有更好的兼容性。本文对PECVD SiC作为MEMS耐化学腐蚀材料进行了系统的研究。SiC被用作涂层,保护微加工多晶硅器件免受侵蚀环境的影响,并作为湿蚀刻掩膜来图案硅和玻璃。利用碳化硅化学稳定性的优点,也用碳化硅来构建微结构。
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引用次数: 10
Nonafiber Membrane of EVOH-Based Ionomer by Electrospinning 静电纺丝法制备evoh基离聚体非纤维膜
W. Jin, Hongwei Duan, Yujun Zhang, Feng-fu Li
Electrospinning is a straightforward and effective technique to produce nanofiber nonwovens. In this paper, a comb ionomer of poly(ethylene covinyl alcohol) end-capped with sulfonic acid (EVOH-g-SO 3H) was synthesized by two-step synthesis process and electrospun into nonwoven membranes. The effect of processing parameters on the fibrous and beads morphology was investigated by scanning electron microscopy (SEM). The result indicated that the morphology of EVOH-g-SO3H membrane was heavily dependent on the electrospinning process as the electrospinning voltage (v), the concentration of polymer solution (c), the surface tension of polymer solution (sigma), the solution flow-rate (upsi), and the deposition distance between the syringe needle and the collecting drum (1). A 'beads-on-string' morphology could be seen from SEM image when the solution was electrospun in DMAc/water while decreasing the surface tension is a good way towards the formation of fibers without beads. When the solution concentration reaches 35wt%, a melded twist-ribbon structure could appear. There is an optimum range of solution concentration (5.0~20.0wt%) for a stable electrospinning and nonwoven formation. A higher applied voltage could result in a higher electric charge density on the surface of polymer solution jet during the electrospinning, they cause the higher splitting to the polymer jet and result in higher density and smaller diameter of round beads, as well as they also produce the thinner diameters fibers
静电纺丝是生产纳米纤维非织造布的一种简单有效的技术。本文采用两步法合成了端部以磺酸为底的聚乙烯醇(evoh -g- so3h)梳状离聚体,并用静电纺丝制备了无纺布膜。利用扫描电子显微镜(SEM)研究了工艺参数对纤维和微球形貌的影响。结果表明:静电纺丝电压(v)、聚合物溶液浓度(c)、聚合物溶液表面张力(sigma)、溶液流速(upsi)、在DMAc/水中静电纺丝时,SEM图像可以看到“串上珠”的形貌,而降低表面张力是形成无珠纤维的好方法。当溶液浓度达到35wt%时,可出现融合的扭带结构。对于稳定的静电纺丝和非织造布的形成,溶液浓度的最佳范围为5.0~20.0wt%。在静电纺丝过程中,施加电压越高,聚合物溶液射流表面的电荷密度越高,它们对聚合物射流的劈裂作用越大,形成的圆珠密度越大,直径越小,纤维直径越细
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引用次数: 1
Carbon Nanotubes as Heating Elements for Micro-Bubble Generation 碳纳米管作为微泡产生的加热元件
Wenli Zhou, G. Chow, W.J. Li, P. Leong
Development and preliminary characterization on the performance of a micro-bubble generator using carbon nanotubes (CNTs) as heating elements are presented. Dielectrophoretic force was used to align CNTs between fabricated micro-electrodes. The contacts between the CNTs and electrodes were fixed by patterned SiO2 thin film. Localized high temperature due to Joule-heating generated by an AC current of a few hundred muA (in general les100 Hz) in the carbon nanotubes vaporized surrounding water and generated micron sized bubbles (with diameter of 5 mum detectable under normal optical microscope). These experimental evidence indicate that exposed CNTs may function as a single nucleation site for bubble generation. The power required to generate these bubbles can be as small as 337 muW, which is with 1-2 order of magnitude smaller than that of typical metal or polysilicon based MEMS heaters. Precisely controlled micro bubble generation may find promising applications in ink-jet printing, micro-fluidic visualization, or micro-fluidic based bio-manipulation
介绍了以碳纳米管(CNTs)为加热元件的微泡发生器的研制及其性能的初步表征。介电泳力用于在制备的微电极之间对齐碳纳米管。碳纳米管与电极之间的接触通过图案化的SiO2薄膜固定。在碳纳米管中,几百μ a(一般小于100 Hz)的交流电流产生焦耳加热,产生局部高温,使周围的水蒸发并产生微米大小的气泡(在普通光学显微镜下可检测到直径为5 μ m)。这些实验证据表明,暴露的碳纳米管可能是气泡产生的单一成核位点。产生这些气泡所需的功率可小至337 muW,比典型的金属或多晶硅基MEMS加热器小1-2个数量级。精确控制的微气泡产生可能在喷墨打印,微流体可视化或基于微流体的生物操作中找到有前途的应用
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引用次数: 7
Scaling Magnetic Actuators Beyond the Single-Domain Limit 超出单畴限制的伸缩磁致动器
D.J. Vasquez, J. Judy
Ferromagnetic sensors and actuators have been extensively studied on the microscale and have led to the development of optical switches [Judy, JW & Muller, RS, 1997], magnetically-tunable frequency-selective surfaces [Zendejas, J, et al., 2002], magnetic assembly of out-of-plane-MEMS devices [Chen, J, et al., 2001], and low-power to zero-power magnetometers [Yang, HH, et al., 2002; Vasquez, DJ & Judy, JW, 2004]. For many devices and applications there exist advantages in reducing the size of the system. The authors of this paper are studying the benefits and limitations of decreasing the scale of magnetic actuators. We have designed, fabricated, and tested torsional magnetic actuators that consist of a 1250-nm-long, 85-nm-wide, and 30-nm-thick magnetic element that is attached to a pair of 50-nm-thick, 100-nm-wide, and 2000-nm-long torsion beams
铁磁传感器和执行器在微尺度上得到了广泛的研究,并导致了光开关的发展[Judy, JW和Muller, RS, 1997],磁可调谐频率选择表面[Zendejas, J, et al., 2002],面外mems器件的磁组装[Chen, J, et al., 2001],以及低功率到零功率磁强计[Yang, HH, et al., 2002;Vasquez, DJ & Judy, JW, 2004]。对于许多设备和应用来说,减小系统尺寸是有好处的。本文的作者正在研究减小磁性执行器的规模的好处和局限性。我们已经设计、制造和测试了由1250纳米长、85纳米宽和30纳米厚的磁性元件组成的扭转磁致动器,该磁力元件连接到一对50纳米厚、100纳米宽和2000纳米长的扭转梁上
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引用次数: 1
Design MEMS Actuators with Topology Optimization Method 用拓扑优化方法设计MEMS驱动器
Kongtian Zuo, Yudong Zhao, Yong-gao Xie, Liping Chen
Topology optimization method is a novel design method for MEMS actuators. In this paper, a multi-objective design method is introduced into topology optimization for MEMS actuators. Some important factors for multi-objective design of MEMS actuators are deeply researched. A multi-objective topology optimization method based on minimal structural compliance and maximal structural output displacement of MEMS actuators is proposed and the corresponding governing equation for topology optimization is established. A sensitivity analysis of adjoint method is proposed to analyze topology optimization design of multi-objective MEMS actuators. Meanwhile, GCMMA (globally convergent version of the method of moving asymptotes) algorithm is used in optimization. Two numerical examples of MEMS actuators verified the effectiveness of above theory and algorithm
拓扑优化方法是一种新颖的MEMS执行器设计方法。本文将多目标设计方法引入到MEMS作动器的拓扑优化中。深入研究了MEMS作动器多目标设计的一些重要因素。提出了一种基于结构柔度最小和结构输出位移最大的多目标拓扑优化方法,并建立了相应的拓扑优化控制方程。针对多目标MEMS致动器的拓扑优化设计,提出了伴随法的灵敏度分析方法。同时,采用GCMMA(全局收敛版的移动渐近线法)算法进行优化。两个MEMS作动器的数值算例验证了上述理论和算法的有效性
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引用次数: 2
期刊
2006 1st IEEE International Conference on Nano/Micro Engineered and Molecular Systems
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