This study compares the “cavitation to no-cavitation” transition processes and the resulting pressure oscillation effects of water, liquid oxygen and liquid methane in an adjustable cavitation Venturi tube through back pressure experiments. The modal characteristics of cavitation images and the frequency domain characteristics of vibrations were analyzed using the proper orthogonal decomposition (POD) and fast Fourier transform (FFT). By observing with a transparent Venturi tube and high-speed photography, combined with one-dimensional homogeneous flow simulation, the evolution laws of cavitation length and downstream pressure oscillation during the processes of changing the pressure ratio pr and the throat area At were studied. The evolution laws of cavitation length and flow pattern about working parameters were obtained, revealing the correlation between cavitation and vibration. Under low pressure ratios, the oscillation of bubble collapse dominated by the returning jet causes the tail of the cavitation area to be lengthened, resulting in an increase in downstream amplitude. Increasing the pressure ratio can effectively control the cavitation length and reduce the amplitude of downstream pressure oscillation. Reducing the throat area by moving the plug cone increases the cavitation length, and the downstream oscillation amplitude first increases and then decreases, with an oscillation maximum value existing.