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2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)最新文献

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Characterization of Smart Hydrogel-Based Ultrasound Resonators for Implantable Sensing Applications 用于植入式传感应用的智能水凝胶超声谐振器的表征
Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495729
Navid Farhoudi, P. Kairy, J. Magda, F. Solzbacher, C. Reiche
Many biomedical sensing concepts for continuous monitoring of analytes rely on implanting electronic components inside the body to operate, which raises issues about long-term biocompatibility. In recent reports, an implantable sensing modality was reported in which ultrasound absorption in smart hydrogel resonators at a particular probing frequency is used to track the changes in ionic strength and glucose concentration of an analyte solution. This sensing concept allows the implanted component to be free from electronics, with corresponding possible advantages with respect to biocompatibility and lifetime of the device. However, an unsuitable probing frequency can undermine the received signal's quality from the implants or even entirely cause a signal loss. Here we present our work on creating an ultrasound characterization system and using it to determine optimum probing frequencies for the hydrogel resonator structures within a given frequency window. Furthermore, we demonstrate that the signal amplitude depends on the probing frequency's location relative to the frequency response peaks at a fixed dynamic range for swelling of smart hydrogels.
许多生物医学传感概念对分析物的持续监测依赖于在体内植入电子元件来操作,这引起了长期生物相容性的问题。在最近的报道中,报道了一种植入式传感模式,其中智能水凝胶谐振器在特定探测频率下的超声吸收用于跟踪分析物溶液的离子强度和葡萄糖浓度的变化。这种传感概念允许植入的组件不受电子器件的影响,在生物相容性和设备寿命方面具有相应的可能优势。然而,不合适的探测频率会破坏从植入物接收到的信号质量,甚至完全导致信号丢失。在这里,我们介绍了我们在创建超声表征系统并使用它来确定在给定频率窗口内水凝胶谐振器结构的最佳探测频率方面的工作。此外,我们证明了信号幅度取决于探测频率相对于智能水凝胶膨胀在固定动态范围内的频率响应峰的位置。
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引用次数: 0
Single-Chip Integration of CMOS Compatible Mems Temperature/Humidity and Highly Sensitive Flow Sensors for Human Thermal Comfort Sensing Application CMOS兼容Mems温度/湿度和高灵敏度流量传感器的单芯片集成,用于人体热舒适传感应用
Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495565
Izhar, Wei-Qing Xu, Hadi Tavakkoli, Jose Cabot, Xu Zhao, Mingzheng Duan, Yi-Kuen Lee
In this work, we report a single-chip integration of CMOS compatible MEMS temperature, humidity, and highly sensitive flow sensor for the application of human thermal comfort (HTC) sensing. The present multi-sensors chip (MSC) comes up with a couple of merits. Firstly, it utilizes a low-cost 3-mask fabrication process to fabricate temperature, humidity, and flow sensors on a single chip with a proper packaging layer (parylene C) that acts as both packaging (for temperature & flow sensors) and a humidity sensing layer. Secondly, a fully released thermoresistive calorimetric flow (TCF) sensor with dual pairs of detectors is fabricated to achieve high sensitivity. The fabricated (flow, humidity, and temperature) sensors were characterized under different air velocities, humidity, and temperature levels, respectively. The measurement results indicated a maximum sensitivity of 312 mV/ms−1 for the developed TCF sensor with dual detectors design which is almost doubled compared to conventional single pair of detectors design. Furthermore, the humidity sensor achieved an average sensitivity of 7.83 fF/%RH, whereas the temperature sensor shows a resistance change of $5.78Omega/^{circ}mathrm{C}$ and TCR of $1.43 times 10^{-3}/^{circ} mathrm{C}$. The experimental results indicated that our MSC is promising for the HTC sensing application for smart buildings in the era of Internet of Things (IoT).
在这项工作中,我们报道了一种集成CMOS兼容MEMS温度、湿度和高灵敏度流量传感器的单片机,用于人体热舒适(HTC)传感。目前的多传感器芯片(MSC)具有几个优点。首先,它利用低成本的3掩模制造工艺在单个芯片上制造温度、湿度和流量传感器,并使用适当的封装层(聚对二甲苯C)作为封装(用于温度和流量传感器)和湿度传感层。其次,为了实现高灵敏度,制作了具有双对检测器的全释放热阻量热流传感器。制备的传感器(流量、湿度和温度)分别在不同的空气速度、湿度和温度水平下进行了表征。测量结果表明,采用双探测器设计的TCF传感器的最大灵敏度为312 mV/ms−1,几乎是传统单对探测器设计的两倍。此外,湿度传感器的平均灵敏度为7.83 fF/%RH,而温度传感器的电阻变化为5.78Omega/^{circ}mathrm{C}$, TCR为1.43 乘以10^{-3}/^{circ} mathrm{C}$。实验结果表明,我们的MSC在物联网(IoT)时代的智能建筑中具有广阔的应用前景。
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引用次数: 4
Corrosion Monitoring Of Sacrificial Anodes Based On Contour Plot Analysis Of Electro-Mechanical Impedance Spectra 基于机电阻抗谱等值线图分析的牺牲阳极腐蚀监测
Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495493
Jeslin Thalapil, Durgesh U. Tamhane, Sauvik Banerjee, S. Tallur
In this paper, we utilize a graphical technique originally proposed for damage assessment in beams, to determine the extent of corrosion of sacrificial zinc anode discs instrumented with piezoelectric transducers using Electro-Mechanical Impedance (EMI) measurements. The underlying parameters determining extent of corrosion (thicknesses of the zinc and zinc oxide films) are extracted from measured resonance frequencies of radial and transverse vibration modes by finding roots of the characteristic equations of these modes graphically through contour plot. This technique shows excellent agreement with experimental results, requires no calibration and is computationally inexpensive unlike optimization techniques.
在本文中,我们利用最初提出的用于梁损伤评估的图形技术,利用机电阻抗(EMI)测量来确定带有压电换能器的牺牲锌阳极盘的腐蚀程度。通过等高线图求径向和横向振动模态特征方程的根,从测量到的共振频率中提取出决定腐蚀程度的基本参数(锌和氧化锌膜的厚度)。该技术与实验结果非常吻合,不需要校准,与优化技术不同,计算成本低廉。
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引用次数: 0
A Vacuum-Driven Microfluidic Array for Multi-Step Sample Digitalization 用于多步样品数字化的真空驱动微流控阵列
Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495676
Jiumei Hu, Liben Chen, Pengfei Zhang, K. Hsieh, Hui Li, Tza-Huei Wang
We present herein a facile vacuum-driven microfluidic device that is capable of multi-step sample digitalization based on the gas permeability of PDMS. The device features 1) a suction layer that is connected to an external vacuum to generate a continuous negative pressure within the device, and 2) an outlet-free microarray layer with treelike multi-level bifurcated microchannels connecting to 4096 dead-end microwells to realize multiple loading steps until all the microwells being filled. To efficiently prevent sample evaporation at high temperatures, we use a glass slide that is pre-poured with thermosetting oil to seal the gas-permeable PDMS. Moreover, we demonstrated successful detection of single-cell methicillin-resistant Staphylococcus aureus (MRSA) with three loading steps targeting the resistance marker gene MecA via digital PCR amplification on the device.
基于PDMS的透气性,我们设计了一种简易的真空驱动微流控装置,可实现样品的多步数字化。该器件具有:1)与外部真空相连的吸层,在器件内产生连续的负压;2)无出口微阵列层,具有树形多级分分叉微通道,与4096个终端微孔相连,实现多个加载步骤,直至所有微孔都被填充。为了有效地防止样品在高温下蒸发,我们使用预先倒入热固性油的玻璃载玻片来密封透气性PDMS。此外,我们展示了成功检测单细胞耐甲氧西林金黄色葡萄球菌(MRSA)通过三个加载步骤针对耐药标记基因MecA通过数字PCR扩增装置。
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引用次数: 0
Intersecting Book Inspired High-Power-Density Electret/Triboelectric Multilayered Power Generator with Flexible Interdigital Electrodes 具有柔性数字间电极的高功率密度驻极体/摩擦电多层发电机
Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495628
Hao Huang, Zhe Zhao, K. Tao, Jin Wu, Bowen Ji, W. Yuan, Honglong Chang
Inspired by the classic friction phenomenon in life, a multi-layer interdigital Electret/Triboelectric Multilayered Power Generator (ET-MPG) that imitates the friction of book pages is designed. Its production is based on a flexible substrate and has special properties that other rigid devices do not have. For example, a very small positive pressure can increase its output performance by 80%, and the final peak power density can reach 0.18W/m2. Through exploration experiments, it is known that the number of output peaks of the interdigital electrode has a corresponding relationship with the number of figures, and the output performance can be multiplied. When the sliding rate is 1m/s, the highest peak voltage reaches 30 V, the average output power of a single layer reaches 10 µW, and the power density can reach 54 mW/m2 in the preliminary results. In addition, by exploring the influencing factors of the friction between the intersecting books, we can understand the large amount of energy contained in this multi-layer flexible structure. The peak energy density of a single page reaches 2.3 J/m2. In addition, the electret generator not only has a high-performance output, but also because it uses all flexible materials, its wearing comfort is unmatched by other rigid devices. This is of great significance to the energy supply of wearable devices and the energy collection on the surface of the human body.
受生活中经典摩擦现象的启发,设计了一种模拟书本页面摩擦的多层数字间驻极体/摩擦电多层发电机(ET-MPG)。它的生产基于柔性衬底,具有其他刚性器件所不具备的特殊性能。例如,非常小的正压可使其输出性能提高80%,最终峰值功率密度可达到0.18W/m2。通过探索性实验可知,数字间电极的输出峰数与图数有对应关系,输出性能可成倍提高。当滑动速率为1m/s时,最高峰值电压达到30 V,单层平均输出功率达到10µW,初步结果显示功率密度可达54 mW/m2。此外,通过探究相交书之间摩擦的影响因素,我们可以了解到这种多层柔性结构中蕴含的大量能量。单页峰值能量密度达到2.3 J/m2。此外,驻极体发生器不仅具有高性能的输出,而且由于其全部采用柔性材料,其佩戴舒适性是其他刚性器件无法比拟的。这对可穿戴设备的能量供给和人体表面的能量收集具有重要意义。
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引用次数: 0
A Microfluidic Device Platform Reconstructing Lung Pattern for Cancer Immunotherapy Applications 一种用于肿瘤免疫治疗的肺形态重建微流控装置平台
Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495673
Yu-Chen Chen, Han-Jung Liao, Jean-An Chich, Pin-Tzu Lai, Yi-Ying Liang, Kang-Yun Lee, Wei-Lun Sun, S. Ho, Yu-Shiuan Wang, Wan-Chen Huang, Wei-Chiao Chang, Sung-Yang Wei, Cheng-Hsien Liu
Cancer is one of the leading causes of death globally. To simulate a similar environment of human tissue is the difficulty in cancer research. The development of 3D culture model is used to imitate the environment to provide a potential research strategy. Matrigel is the most commonly used material for 3D culture models. However, it is derived from murine tumors, unsuitable for clinical applications. In this study, the methacrylated gelatin (GelMA) was blended with type I collagen as a biomaterial in our microfluidic device. We further optimized the device design; it can perform entirely experimental functions without requiring complicated parts such as pumps and valves. On this microfluidic platform, the biocompatible hydrogel and cells could be patterned via liquid dielectrophoresis (LDEP) and dielectrophoretic force (DEP). The experimental results demonstrated that the human lung cancer cells were patterned via both DEP/LDEP and light-curing hydrogel with low cell mortality. The patterned cells' mortality rate is less than 5% after 24 hr of cultivation. Our results suggest the potential of this device for future clinical cancer study applications. Furthermore, we also expect to achieve bionic tumors and explore the interaction between 3D cell models and drugs.
癌症是全球死亡的主要原因之一。模拟类似的人体组织环境是癌症研究的难点。利用三维培养模型的发展来模拟环境,为研究提供潜在的策略。矩阵是3D培养模型最常用的材料。然而,它来源于小鼠肿瘤,不适合临床应用。在本研究中,甲基丙烯酸明胶(GelMA)与I型胶原蛋白混合作为微流控装置中的生物材料。我们进一步优化了器件设计;它可以完全执行实验功能,而不需要复杂的部件,如泵和阀门。在该微流控平台上,生物相容性水凝胶和细胞可以通过液体介电泳(LDEP)和介电泳力(DEP)进行图图化。实验结果表明,DEP/LDEP和光固化水凝胶均可制备人肺癌细胞,且细胞死亡率低。培养24小时后,花纹细胞死亡率低于5%。我们的研究结果表明该装置在未来临床癌症研究中的应用潜力。此外,我们还期望实现仿生肿瘤,并探索三维细胞模型与药物的相互作用。
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引用次数: 0
A Compact Acoustic Particle Velocity Gradient Sensor Based on MEMS Hot-Wire Sensor Chips 基于MEMS热线传感器芯片的小型声粒子速度梯度传感器
Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495574
Lingmeng Yang, Zhezheng Zhu, Wenhan Chang, Fanrui Meng, Chengchen Gao, Y. Hao, Zhenchuan Yang
A compact and superdirective particle velocity gradient (PVG) sensor based on two MEMS hot-wire acoustic particle velocity sensor (APVS) chips is proposed. The capability of directly measurement of second-order directionality of acoustic field makes the PVG sensors are more competitive than currently used acoustic vector sensors or microphone arrays, while the compact design can broaden their working frequency. With the APVS spacing of 3.6mm, the measured directional patterns are all cosine squared shape up to 5 kHz, which demonstrated the feasibility for directly acquirement of second-ordered directionality. The sensor could be monolithic integrated to further shorten the spacing of velocity sensors, and to be more competitive for high-sound-frequency and narrow-space directional acoustic sensing applications.
提出了一种基于两个MEMS热线声粒子速度传感器(APVS)芯片的紧凑超定向粒子速度梯度(PVG)传感器。直接测量声场二阶方向性的能力使PVG传感器比目前使用的声矢量传感器或传声器阵列更具竞争力,而紧凑的设计可以拓宽其工作频率。当APVS间距为3.6mm时,测量到的方向图在5 kHz范围内均为余弦平方形状,证明了直接获取二阶方向性的可行性。该传感器可以单片集成,进一步缩短速度传感器的间距,并在高频率和窄空间定向声传感应用中更具竞争力。
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引用次数: 2
All-Polymer Soft-X-Ray-Charged Piezoelectret for Push-Button Energy Harvester 用于按钮能量收集器的全聚合物软x射线充电压电体
Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495733
Jia Lu, Yuji Suzuki
Piezoelectret using space-charged porous polymers attracts much attention due to its high piezoelectric coefficient. In the present study, a novel all-polymer soft-X-ray-charged multilayer piezoelectret is proposed for push-button energy harvesting. The prototype is microfabricated using a parylene-C structural layer with patterned gap-control protrusions, dip-coated PEDOT:PSS electrode, and a dip-coated polymer electret layer. With the current prototype, up to 24.6 µJ electrical energy has been obtained with a single pushing force of only 1.3 N, corresponding to a record-high piezoelectric coefficient d33 of 105 nC/N, 30 times higher than conventional MEMS-based piezoelectrets.
利用空荷多孔聚合物制备的压电极体因其具有较高的压电系数而备受关注。在本研究中,提出了一种新型的全聚合物软x射线多层压电极体用于按钮能量收集。该原型是使用带有图案间隙控制突起的聚苯乙烯-c结构层、浸涂PEDOT:PSS电极和浸涂聚合物驻极体层进行微加工的。在目前的原型中,单次推力仅为1.3 N,就可以获得高达24.6µJ的电能,对应于创纪录的105 nC/N的压电系数d33,比传统的基于mems的压电体高30倍。
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引用次数: 0
First Jumps of a Silicon Microrobot with an Energy Storing Substrate Spring 带有储能衬底弹簧的硅微型机器人的初跳
Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495685
Craig B. Schindler, Hani C. Gomez, K. Pister
We present the first-ever successful jumps of a microrobot fabricated in a silicon-on-insulator (SOI) process with an energy storing spring etched into the silicon substrate. The 0.08 gram silicon robot used its onboard electrostatic inchworm motor to store 8µJ of spring energy and vertically jump more than 3mm when powered and controlled with wire tethers. The robot's vertical jump height is more than 3X higher than what has been previously demonstrated by an SOI robot.
我们提出了一个微型机器人的第一次成功的跳跃在硅绝缘体上的硅(SOI)工艺制造的能量存储弹簧蚀刻到硅衬底。这款0.08克重的硅制机器人利用其内置的静电尺蠖电机存储8µJ的弹簧能量,在用绳索供电和控制时,可以垂直跳跃超过3毫米。该机器人的垂直跳跃高度比之前SOI机器人展示的高度高出3倍以上。
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引用次数: 0
Particle Size Determination in Impedance Flow Cytometry Using Measured Opacity 采用测量不透明度的阻抗流式细胞术测定颗粒大小
Pub Date : 2021-06-20 DOI: 10.1109/Transducers50396.2021.9495740
Douwe S de Bruijn, K. F. Jorissen, W. Olthuis, A. van den Berg
Microfluidic electrical flow cytometry is a popular method to study a wide variety of biological cell properties. Unfortunately, when using coplanar electrodes, this method is sensitive to positional differences of passing particles or cells. In this work we present a novel compensation method to account for the particle position in a coplanar electrode setup using the measured electrical opacity. We demonstrate an accurate size discrimination of 5, 6 and 7 µm polystyrene beads irrespective of their position using the measured electrical opacity making use of the variation of electrical field strength with height in the channel. Thus, only two electrodes are required, which is favorable for microfluidic devices with size limitations.
微流控电流式细胞术是研究多种生物细胞特性的常用方法。不幸的是,当使用共面电极时,这种方法对通过的粒子或细胞的位置差异很敏感。在这项工作中,我们提出了一种新的补偿方法,利用测量的电不透明度来解释共面电极设置中的粒子位置。我们利用电场强度随通道高度的变化,利用测量的电不透明度,证明了5,6和7 μ m聚苯乙烯珠的精确尺寸判别,而不管它们的位置如何。因此,只需要两个电极,这有利于具有尺寸限制的微流体装置。
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引用次数: 1
期刊
2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)
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