Enfermedades infecciosas y microbiologia clinica (English ed.)最新文献

英文中文

Usefulness of decentralized sequencing networks on antimicrobial resistance surveillance 分散测序网络对抗菌药耐药性监测的作用。

Enfermedades infecciosas y microbiologia clinica (English ed.)

Pub Date : 2024-10-01 DOI: 10.1016/j.eimce.2024.04.013

引用次数: 0

Proposing the change of name of viruela del mono (monkeypox) in Spanish to viruela M 建议将 "猴痘病毒"（viruela del mono）的西班牙语名称改为 "猴痘病毒"（viruela M）。

Enfermedades infecciosas y microbiologia clinica (English ed.)

Pub Date : 2024-10-01 DOI: 10.1016/j.eimce.2024.08.001

Francisco Javier Membrillo de Novales , Jaime García Iglesias , Miriam Álvarez , Luis E. Cuellar , María Eugenia Gutiérrez-Pimentel , Alexis M. Holguin , Virgilio Lezcano , Susana Lloveras , Mariella Raijmakers , Iván Arturo Rodríguez Sabogal , Adriana Sucari , Alfonso J. Rodriguez-Morales , on behalf of the Latin American Alliance for Infectious Diseases and Clinical Microbiology (ALEIMC)

引用次数: 0

Infectious pathology imported from the northern hemisphere 从北半球传入的传染病学。

Enfermedades infecciosas y microbiologia clinica (English ed.)

Pub Date : 2024-10-01 DOI: 10.1016/j.eimce.2024.03.003

引用次数: 0

Anticipating the side effects of benznidazole: HLA-B*35 and patch test 预测苯并咪唑的副作用：HLA-B*35 和斑贴试验。

Enfermedades infecciosas y microbiologia clinica (English ed.)

Pub Date : 2024-10-01 DOI: 10.1016/j.eimce.2024.04.011

Introduction

Treatment of Chagas disease frequently causes distress to patients due to a high incidence of adverse effects. Different preemptive tests have been researched to prevent these effects and to allow focus to be given to certain predisposed patients. Benznidazole is the most prescribed Chagas disease treatment in Spain.

In this work, we analyzed the genetic markers HLA-B*35 allele group and HLA-B*35:05 allele specifically, as well as an allergy patch test, as benznidazole's most frequent adverse effects are cutaneous.

Methods

HLA-B intermediate-resolution genotyping was performed followed by a high-resolution level analysis. Cutaneous allergies were tested using strips impregnated with a mixture of benznidazole and placed on the upper back of patients before starting treatment.

Results

In our sample of more than 400 patients, there was almost no relationship between any kind of side effect and either of the HLA-B alleles studied. The patch testing was quickly discarded as a preemptive test due to its low sensitivity (16.7%).

Conclusion

In conclusion, we were unable to replicate and corroborate genetic markers identified by other groups and there is currently no test that can anticipate the adverse effects of benznidazole, therefore, more investigation should be carried out in this field.

导言：南美锥虫病的治疗由于不良反应发生率高，常常给患者带来痛苦。为了预防这些不良反应，并使某些易感患者得到重点治疗，人们研究了不同的预防性试验。在西班牙，苯并咪唑是治疗恰加斯病最常用的处方药。在这项工作中，我们分析了遗传标记 HLA-B*35 等位基因组和 HLA-B*35:05 等位基因，并进行了过敏贴片测试，因为苯并咪唑最常见的不良反应是皮肤过敏。在开始治疗前，使用浸渍了苯并咪唑混合物的试纸条贴在患者的上背部进行皮肤过敏测试：在我们对 400 多名患者的抽样调查中，几乎没有发现任何一种副作用与所研究的任何一种 HLA-B 等位基因有关。由于贴片测试的灵敏度较低（16.7%），我们很快就放弃了将其作为预防性测试的做法：总之，我们无法复制和证实其他研究小组发现的遗传标记，目前也没有任何检测方法可以预测苯并咪唑的不良反应，因此，应在这一领域开展更多研究。

{"title":"Anticipating the side effects of benznidazole: HLA-B*35 and patch test","authors":"","doi":"10.1016/j.eimce.2024.04.011","DOIUrl":"10.1016/j.eimce.2024.04.011","url":null,"abstract":"<div><h3>Introduction</h3><div>Treatment of Chagas disease frequently causes distress to patients due to a high incidence of adverse effects. Different preemptive tests have been researched to prevent these effects and to allow focus to be given to certain predisposed patients. Benznidazole is the most prescribed Chagas disease treatment in Spain.</div><div>In this work, we analyzed the genetic markers HLA-B*35 allele group and HLA-B*35:05 allele specifically, as well as an allergy patch test, as benznidazole's most frequent adverse effects are cutaneous.</div></div><div><h3>Methods</h3><div>HLA-B intermediate-resolution genotyping was performed followed by a high-resolution level analysis. Cutaneous allergies were tested using strips impregnated with a mixture of benznidazole and placed on the upper back of patients before starting treatment.</div></div><div><h3>Results</h3><div>In our sample of more than 400 patients, there was almost no relationship between any kind of side effect and either of the HLA-B alleles studied. The patch testing was quickly discarded as a preemptive test due to its low sensitivity (16.7%).</div></div><div><h3>Conclusion</h3><div>In conclusion, we were unable to replicate and corroborate genetic markers identified by other groups and there is currently no test that can anticipate the adverse effects of benznidazole, therefore, more investigation should be carried out in this field.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"42 8","pages":"Pages 430-434"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges and strategies in the prevention of dengue: A challenge for public health 预防登革热的挑战和战略：公共卫生面临的挑战。

Enfermedades infecciosas y microbiologia clinica (English ed.)

Pub Date : 2024-10-01 DOI: 10.1016/j.eimce.2024.04.006

引用次数: 0

Addressing catheter lock therapy: Does heparin reduce the bioactivity of dalbavancin when together in solution during freezing? 解决导管锁定疗法：肝素与达巴万星一起在溶液中冷冻时是否会降低达巴万星的生物活性？

Enfermedades infecciosas y microbiologia clinica (English ed.)

Pub Date : 2024-10-01 DOI: 10.1016/j.eimce.2024.02.013

Introduction

The possible use of dalbavancin as a catheter lock solution was previously demonstrated by our study group. However, it was needed to assess whether heparin could affect dalbavancin bioactivity during freezing storage.

Methods

We tested the bioactivity of a dalbavancin + heparin (DH) vs. dalbavancin (D) against Staphylococcal biofilms comparing DH median value of cfu counts and metabolic activity with that obtained for D before and during storage under freezing up to 6 months.

Results

Despite there was a slight decrease in the median percentage reduction of metabolic activity at month 3 in Staphylococcus epidermidis between DH and D (97.6 vs. 100, p = 0.037), considering the clinical criteria, no significant reduction in any of the variables tested was observed at the end of the experiment between D and DH solutions.

Conclusion

The addition of heparin to a dalbavancin lock solution did not affect its bioactivity against staphylococcal biofilms irrespective of its preservation time under freezing.

简介我们的研究小组曾证实达巴万星可用作导管锁定溶液。然而，我们需要评估肝素在冷冻储存期间是否会影响达巴万星的生物活性：我们测试了达巴万星+肝素（DH）与达巴万星（D）对葡萄球菌生物膜的生物活性，比较了 DH 与 D 在冷冻前和冷冻储存长达 6 个月期间获得的 cfu 计数和代谢活性的中值：结果：尽管在第 3 个月时，DH 和 D 的表皮葡萄球菌代谢活性降低的中位数百分比略有下降（97.6 对 100，p=0.037），但考虑到临床标准，在实验结束时，D 和 DH 溶液的任何测试变量均未观察到显著降低：结论：在达巴万星锁定溶液中添加肝素不会影响其对葡萄球菌生物膜的生物活性，无论其在冷冻条件下的保存时间长短。

{"title":"Addressing catheter lock therapy: Does heparin reduce the bioactivity of dalbavancin when together in solution during freezing?","authors":"","doi":"10.1016/j.eimce.2024.02.013","DOIUrl":"10.1016/j.eimce.2024.02.013","url":null,"abstract":"<div><h3>Introduction</h3><div>The possible use of dalbavancin as a catheter lock solution was previously demonstrated by our study group. However, it was needed to assess whether heparin could affect dalbavancin bioactivity during freezing storage.</div></div><div><h3>Methods</h3><div>We tested the bioactivity of a dalbavancin+heparin (DH) vs. dalbavancin (<em>D</em><span>) against Staphylococcal biofilms comparing DH median value of cfu counts and metabolic activity with that obtained for </span><em>D</em> before and during storage under freezing up to 6 months.</div></div><div><h3>Results</h3><div>Despite there was a slight decrease in the median percentage reduction of metabolic activity at month 3 in <span><span>Staphylococcus epidermidis</span></span><span> between DH and </span><em>D</em> (97.6 vs. 100, <em>p</em>  <!-->0.037), considering the clinical criteria, no significant reduction in any of the variables tested was observed at the end of the experiment between <em>D</em> and DH solutions.</div></div><div><h3>Conclusion</h3><div>The addition of heparin to a dalbavancin lock solution did not affect its bioactivity against staphylococcal biofilms irrespective of its preservation time under freezing.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"42 8","pages":"Pages 435-438"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140875062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sinus fungal balls caused by Syncephalastrum spp.: 2 clinical cases and literature review 由头癣菌属引起的鼻窦真菌球：2 个临床病例和文献综述。

Enfermedades infecciosas y microbiologia clinica (English ed.)

Pub Date : 2024-10-01 DOI: 10.1016/j.eimce.2024.06.005

Introduction

Syncephalastrum spp. is a mucoral that rarely produces pathology. Fungal balls caused by this genus are infrequent. It requires early diagnosis and treatment to avoid associated morbidity and mortality.

Methods

We describe two clinical cases of sinus fungus balls caused by Syncephalastrum spp. and review the literature.

Results

Two patients were treated for sinus fungus balls. When their samples were analysed, the aetiology was determined to be Syncephalastrum spp. A case of pulmonary fungus ball due to Syncephalastrum spp. is described in the literature. All cases, including these described in the present study, had a good evolution after treatment.

Conclusions

Syncephalastrum spp. is a filamentous fungus that should be considered as an aetiology of sinus fungus ball.

简介Syncephalastrum spp.是一种粘菌，很少引起病变。由该菌属引起的真菌球并不常见。它需要早期诊断和治疗，以避免相关的发病率和死亡率：方法：我们描述了两例由Syncephalastrum属真菌引起的鼻窦真菌球的临床病例，并回顾了相关文献：结果：两名患者接受了鼻窦真菌球治疗。结果：两名患者因鼻窦真菌球接受了治疗，在对他们的样本进行分析后，确定病原体为合头菌属。包括本研究中描述的病例在内的所有病例在治疗后都获得了良好的发展：综合头孢菌属是一种丝状真菌，应被视为鼻窦真菌球的病原体。

引用次数: 0

Spatial analysis for risk assessment of dengue in Spain 西班牙登革热风险评估的空间分析。

Enfermedades infecciosas y microbiologia clinica (English ed.)

Pub Date : 2024-10-01 DOI: 10.1016/j.eimce.2023.06.010

Introduction

The establishment of Aedes albopictus in new areas in Europe has changed the risk of local dengue transmission represented by imported human cases. The risk of transmission is determined by the distribution of travelers arriving from dengue-endemic areas and the distribution of Ae. albopictus as potential vectors of dengue in Spain.

Methods

Environmental, entomological, epidemiological, demographic, tourism and travel data were analyzed to produce a series of maps to represent: the distribution of Ae. albopictus across municipalities; the risk of expansion of Ae. albopictus based on a species distribution model; the calculated index of travelers from dengue-endemic areas (IDVZE) per province; the percentage contribution of each municipality to the total number of cases in Spain. The maps were then added using map algebra, to profile the spatial risk of autochthonous dengue in Spain at a municipal level from 2016 to 2018.

Results

Ae. albopictus was detected in 983 municipalities. The calculated IDVZE varied from 0.23 to 10.38, with the highest IDVZE observed in Madrid. The overall risk of autochthonous cases oscillated between 0.234 and 115, with the very high risk and high risk areas detected in the Mediterranean region, mainly in the Levantine coast and some parts of the Balearic Islands. Most of the interior of the peninsula was characterized as low risk.

Conclusion

Prevention and control measures to mitigate the risk of autochthonous dengue should be prioritized for municipalities in the high risk areas integrating early detection of imported dengue cases and vector control.

引言：白纹伊蚊在欧洲新地区的出现改变了以输入性人类病例为代表的登革热本地传播风险。传播风险由来自登革热流行区的旅行者的分布和白纹伊蚊在西班牙作为登革热潜在媒介的分布决定；基于物种分布模型的白纹伊蚊扩大的风险；各省登革热流行区旅行者的计算指数；每个市镇在西班牙病例总数中所占的百分比。然后使用地图代数添加这些地图，以描述2016年至2018年西班牙市级本地登革热的空间风险。结果：983个市镇检测到白纹伊蚊。计算出的IDVZE从0.23到10.38不等，其中马德里的IDVZE最高。本地病例的总体风险在0.234至115之间波动，在地中海地区发现了极高风险和高风险地区，主要在黎凡特海岸和巴利阿里群岛的一些地区。半岛内部大部分地区被定性为低风险地区。结论：高风险地区的市政当局应优先采取预防和控制措施，降低本地登革热的风险，将早期发现输入性登革热病例和病媒控制结合起来。

{"title":"Spatial analysis for risk assessment of dengue in Spain","authors":"","doi":"10.1016/j.eimce.2023.06.010","DOIUrl":"10.1016/j.eimce.2023.06.010","url":null,"abstract":"<div><h3>Introduction</h3><div>The establishment of <em>Aedes albopictus</em> in new areas in Europe has changed the risk of local dengue transmission represented by imported human cases. The risk of transmission is determined by the distribution of travelers arriving from dengue-endemic areas and the distribution of <em>Ae. albopictus</em> as potential vectors of dengue in Spain.</div></div><div><h3>Methods</h3><div>Environmental, entomological, epidemiological, demographic, tourism and travel data were analyzed to produce a series of maps to represent: the distribution of <em>Ae. albopictus</em> across municipalities; the risk of expansion of <em>Ae. albopictus</em> based on a species distribution model; the calculated index of travelers from dengue-endemic areas (IDVZE) per province; the percentage contribution of each municipality to the total number of cases in Spain. The maps were then added using map algebra, to profile the spatial risk of autochthonous dengue in Spain at a municipal level from 2016 to 2018.</div></div><div><h3>Results</h3><div><em>Ae. albopictus</em> was detected in 983 municipalities. The calculated IDVZE varied from 0.23 to 10.38, with the highest IDVZE observed in Madrid. The overall risk of autochthonous cases oscillated between 0.234 and 115, with the very high risk and high risk areas detected in the Mediterranean region, mainly in the Levantine coast and some parts of the Balearic Islands. Most of the interior of the peninsula was characterized as low risk.</div></div><div><h3>Conclusion</h3><div>Prevention and control measures to mitigate the risk of autochthonous dengue should be prioritized for municipalities in the high risk areas integrating early detection of imported dengue cases and vector control.</div></div>","PeriodicalId":72916,"journal":{"name":"Enfermedades infecciosas y microbiologia clinica (English ed.)","volume":"42 8","pages":"Pages 406-413"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72016344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Considerations to the comments on the recommendations of the Spanish Antibiogram Committee (COESANT) for the preparation of Cumulative Antibiotic Sensitivity Reports 对西班牙抗生素检查委员会（COESANT）关于编制抗生素敏感性累积报告的建议的评论意见的考虑。

Enfermedades infecciosas y microbiologia clinica (English ed.)

Pub Date : 2024-10-01 DOI: 10.1016/j.eimce.2024.05.006

引用次数: 0

Not everything aggresive is tumoral: Bartonella henselae osteomyelitis 并非所有侵袭性疾病都是肿瘤：鸡形巴顿氏菌骨髓炎。

Enfermedades infecciosas y microbiologia clinica (English ed.)

Pub Date : 2024-10-01 DOI: 10.1016/j.eimce.2024.05.004

引用次数: 0

首页上一页

下一页尾页

类型

全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

数据库

全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley

期刊

Enfermedades infecciosas y microbiologia clinica (English ed.)

全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.

﹀