Advances in integrative medicine最新文献_第3页

The effectiveness of different modes of acupuncture for mature adult females with obesity: A systematic review and meta-analysis 不同针灸模式对成年女性肥胖症的疗效：系统回顾与荟萃分析

IF 1.7 Q2 Medicine

Advances in integrative medicine

Pub Date : 2024-03-01 DOI: 10.1016/j.aimed.2024.03.003

Chester Yan Jie Ng, Wen Min Ng, Yan Zhao, Linda LD Zhong

Introduction

This study aims to evaluate the clinical efficacy of different modes of acupuncture for obesity treatment in adult females. Auricular Acupuncture (AA), Electroacupuncture (EA), and Manual Acupuncture (MA) were the acupuncture methods evaluated. This was accomplished through a systematic review and meta-analysis.

Methods

Seven electronic databases were searched from inception to May 2022 to source for Randomized Control Trials (RCTs). Acupuncture's effect on obesity in adult females was measured using body mass index (BMI), waist circumference (WC), and body weight (BW). To assess the quality of the RCTs, the Cochrane Collaboration's Risk of Bias Tool was used. Pooled analysis was done using the Review Manager software and the random-effects model was used to account for heterogeneity of the included studies. The differences between treatment groups were reported as mean differences (MD).

Results

12 RCTs were selected through screening of results from electronic databases. The acupuncture and control groups each had 375 and 376 participants, respectively. Body parameters such as BMI, WC, and BW were found to be reduced by AA, EA, and MA. BMI had a MD of −0.81 kg/m² (95% CI= −1.26 to −0.37, P=0.0003), WC had a MD of −1.10 cm (95% CI= −2.08 to −0.12, P=0.03), and BW had a MD of −1.37 kg (95% CI= −2.17 to −0.58, P=0.0007).

Conclusion

Acupuncture showed potential benefits to improve BMI, BW, and WC in obese adult females, indicating its efficacy in treatment. However, these findings must be confirmed by higher-quality RCTs in the future.

引言本研究旨在评估不同针灸方法治疗成年女性肥胖症的临床疗效。针灸方法包括耳针（AA）、电针（EA）和手针（MA）。方法检索了从开始到 2022 年 5 月的七个电子数据库，以查找随机对照试验（RCT）。针灸对成年女性肥胖症的影响通过体重指数（BMI）、腰围（WC）和体重（BW）进行测量。为了评估 RCT 的质量，使用了 Cochrane 协作的偏倚风险工具。使用 "综述管理器 "软件进行汇总分析，并使用随机效应模型来考虑纳入研究的异质性。治疗组之间的差异以平均差（MD）报告。针灸组和对照组分别有 375 名和 376 名参与者。发现 AA、EA 和 MA 均可降低体重指数（BMI）、腹围（WC）和体重（BW）等身体参数。BMI的MD值为-0.81 kg/m² (95% CI= -1.26 to -0.37, P=0.0003)，WC的MD值为-1.10 cm (95% CI= -2.08 to -0.12, P=0.03)，BW的MD值为-1.37 kg (95% CI= -2.17 to -0.58, P=0.0007)。针灸对肥胖成年女性的体重指数、体重和腹围有潜在的改善作用，这表明针灸具有治疗效果，但这些研究结果还需在未来进行更高质量的 RCT 研究来证实。

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引用次数: 0

Effect of Taichi on cognitive function in Breast cancer patients undergoing radiotherapy: A randomized controlled trial 太极拳对接受放疗的乳腺癌患者认知功能的影响：随机对照试验

IF 1.7 Q2 Medicine

Advances in integrative medicine

Pub Date : 2024-03-01 DOI: 10.1016/j.aimed.2024.03.004

Mitali Jaideep Naik,, Purusotham Chippala,

Objective

To evaluate the short-term effect of Tai Chi on cognitive function in breast cancer patients undergoing radiotherapy compared to the control group receiving moderate intensity walking.

Design

Parallel, single blinded, randomized controlled trial.

Setting

Mangaluru, Karnataka, India.

Participants

44 female post-surgery Breast cancer patients undergoing radiotherapy.

Interventions

Based on the inclusion criteria patients were randomly assigned into two groups of 22 each. Group A received the Taichi intervention and Group B received the moderate-intensity walking for 30 min,5 times per week for 3 weeks.

Outcome measure

Functional Assessment of Cancer Therapy Cognitive scale version 3 (FACT-Cog 3)

Randomisation

Each random number was concealed separately within a small opaque envelope (SNOSE) and the subjects were equally allocated into two groups with an allocation of 1:1.

Statistical analysis

Independent sample t-test for between the group comparison and paired t-test for within the group comparison.

Results

There were no statistically significant results found between the groups (p-value > 0.05).

Conclusion

The present randomized controlled trial showed that Tai Chi did not improve the cancer-related cognitive Impairment in Breast cancer patients compared to moderate intensity walking. Clinical Trial Registration number: CTRI/2021/08/036012.

目标与接受中等强度步行的对照组相比，评估太极拳对接受放疗的乳腺癌患者认知功能的短期影响。结果测量癌症治疗认知功能评估量表第 3 版（FACT-Cog 3）随机分配每个随机数字分别隐藏在一个不透明的小信封（SNOSE）中，受试者以 1:1 的分配比例被平均分配到两组。统计分析组间比较采用独立样本t检验，组内比较采用配对t检验。结果组间比较无统计学意义（P值为0.05）。结论本随机对照试验表明，与中等强度的步行相比，太极拳并未改善乳腺癌患者与癌症相关的认知障碍。临床试验注册号CTRI/2021/08/036012.

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引用次数: 0

Effects of Viola odorata syrup on hot flashes and night sweats in menopausal women: A randomized, triple-blind, controlled trial Viola odorata糖浆对更年期妇女潮热和盗汗的影响：三盲随机对照试验

IF 1.7 Q2 Medicine

Advances in integrative medicine

Pub Date : 2024-03-01 DOI: 10.1016/j.aimed.2024.04.001

Fatemeh Zahra Karimi , Nahid Nazari , Fatemeh Lotfi , Seyed Reza Mazloom , Mahdi Yousefi , Hassan Rakhshandeh

Background

Hot flashes and night sweats are among the most common and disruptive symptoms in menopausal women. The present study aimed to assess the effects of Viola odorata syrup on hot flashes and night sweats in menopausal women. V. odorata contain flavonoids, saponins, mucilage, alkaloid, vitamin C, magnesium and melatonin.

Methods

This triple-blind, Randomized Controlled Trial was conducted on 84 menopausal women aged 40–65 years referring to the healthcare centers in Mashhad, Iran. Eligible menopausal women received the V. odorata syrup (5 ml) or placebo twice daily for one month. Data were collected before, during, and after the intervention using valid and reliable daily hot flash checklists. Data analysis was performed in SPSS using independent t-test, Mann-Whitney U test, Friedman test, and Chi-square at the significance level of 0.05.

Results

In the first week (before the intervention), the intervention group (V. odorata syrup) and placebo group (control) were homogenous in terms of the frequency and intensity of hot flashes and night sweats. The Mann-Whitney U test indicated a significant difference in the duration of hot flashes between the two groups. In addition, significant differences were observed between the V. odorata syrup and placebo groups between the mean duration of hot flashes in the second (P = 0.044), third (P = 0.031), fourth (P < 0.001), and fifth weeks (P<0.001), mean frequency of hot flashes in the third, fourth, and fifth weeks (P < 0.001), and mean intensity of hot flashes in the third (P = 0.003), fourth, and fifth weeks (P < 0.001), as well as night sweats in the second week, the mean values of which were significantly lower in the V. odorata group compared to the control group.

Conclusion

V. odorata syrup could reduce the frequency, intensity, and duration of hot flashes since the second week of the treatment. Therefore, the use of this plant is recommended for the reduction of hot flashes and night sweats in menopausal women.

背景潮热和盗汗是更年期妇女最常见、最具干扰性的症状之一。本研究旨在评估臭紫苏糖浆对更年期妇女潮热和盗汗的影响。方法这项三盲随机对照试验的对象是在伊朗马什哈德市医疗保健中心就诊的 84 名 40-65 岁绝经妇女。符合条件的更年期妇女每天两次服用 V. odorata 糖浆（5 毫升）或安慰剂，为期一个月。在干预前、干预期间和干预后，使用有效可靠的每日热潮红检查表收集数据。在 SPSS 中使用独立 t 检验、Mann-Whitney U 检验、Friedman 检验和 Chi-square 进行数据分析，显著性水平为 0.05。曼-惠特尼 U 检验表明，两组在潮热持续时间上存在显著差异。此外，在第二周（P = 0.044）、第三周（P = 0.031）、第四周（P <0.001）和第五周（P<0.001）潮热的平均持续时间，第三周、第四周和第五周潮热的平均频率（P <0.001），第三周（P = 0.003）、第四周和第五周（P <0.001）潮热的平均强度，以及第二周的盗汗，与对照组相比，V. odorata 组的平均值显著降低。因此，建议使用这种植物来减少更年期妇女的潮热和盗汗。

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引用次数: 0

The healthcare workforce, working to ‘full-scope of practice’ 医护人员，努力实现 "全面执业"。

IF 1.7 Q2 Medicine

Advances in integrative medicine

Pub Date : 2024-03-01 DOI: 10.1016/j.aimed.2024.03.005

Susan Arentz

引用次数: 0

Effect of Curcumin and/or Nigella sativa‎ on bone density and quality of life in postmenopausal women with osteoporosis or osteopenia 姜黄素和/或黑麦草对绝经后骨质疏松症或骨质增生妇女骨密度和生活质量的影响

IF 1.7 Q2 Medicine

Advances in integrative medicine

Pub Date : 2024-03-01 DOI: 10.1016/j.aimed.2024.03.002

Farzaneh Usefian , Azizeh Farshbaf- Khalili , Mojgan Mirghafourvand , Majid Mobasseri , Sakineh Mohammad-Alizadeh-Charandabi

Objectives

This study aimed to assess the effect of Curcumin and/or Nigella sativa‎ on bone density parameters (primary outcome) and quality of life (secondary outcome) in postmenopausal women with primary osteoporosis or osteopenia.

Design

Randomized controlled trial with factorial design.

Methods

120 postmenopausal women aged 50–65 years with primary osteoporosis or osteopenia were equally randomized into four groups receiving daily capsules for six months; 1) nanomicellar Curcumin 80 mg, 2) Nigella sativa‎ oil 1000 mg, 3) both, 4) placebo. All groups also received conventional treatments. In addition to the baseline assessment, bone mineral density (BMD), T-score, and Z-score were assessed at six months and quality of life (using the menopause-specific quality of life questionnaire) at two, four, and six months of the interventions.

Results

Five cases were lost to follow-up. No serious side events were reported. After the interventions, significant increases were observed in the femoral neck-BMD within all groups (p<0.01) as well as in the lumbar spine-BMD within the Nigella sativa and nanomicellar Curcumin-Nigella sativa groups (p<0.05). However, there was no statistically significant difference between the groups in terms of bone density parameters and overall quality of life score. In the Curcumin group, vasomotor dimension (adjusted difference −0.90, 95% CI: −1.62 to −0.18) and in the Nigella, sativa‎ group vasomotor (-0.76, −1.50 to −0.03) and physical (-0.61, −1.09 to −0.14) dimensions of quality of life score were significantly better than the placebo group.

Conclusions

The addition of Curcumin, Nigella sativa‎ oil, or their combination does not significantly improve bone density parameters and overall quality of life of postmenopausal women with primary osteoporosis or osteopenia compared to routine treatment, but it can improve vasomotor function of quality of life. We suggest conducting long-term interventions based on the results.

目的本研究旨在评估姜黄素和/或黑麦草对患有原发性骨质疏松症或骨质疏松症的绝经后妇女的骨密度参数（主要结果）和生活质量（次要结果）的影响。方法将 120 名年龄在 50-65 岁之间、患有原发性骨质疏松症或骨质增生的绝经后妇女平均随机分为四组，每组每天服用姜黄素胶囊 6 个月：1）纳米姜黄素 80 毫克；2）黑升麻油 1000 毫克；3）二者；4）安慰剂。所有组别均接受常规治疗。除了基线评估外，还在干预后的两个月、四个月和六个月评估了骨矿物质密度（BMD）、T-score和Z-score，以及生活质量（使用更年期生活质量问卷）。无严重副作用报告。干预后，所有组的股骨颈-BMD 都有明显增加（p<0.01），黑麦草组和纳米姜黄素-黑麦草组的腰椎-BMD 也有明显增加（p<0.05）。不过，在骨密度参数和总体生活质量评分方面，组间差异无统计学意义。姜黄素组的血管运动维度（调整后差异为-0.90，95% CI：-1.62至-0.18）和黑升麻组的血管运动维度（-0.76，-1.50至-0.03）和身体维度（-0.61，-1.09至-0.14）的生活质量评分明显优于安慰剂组。结论与常规治疗相比，添加姜黄素、黑升麻油或它们的复方制剂并不能明显改善原发性骨质疏松症或骨质疏松症绝经后妇女的骨密度参数和整体生活质量，但可以改善血管运动功能和生活质量。我们建议根据研究结果进行长期干预。

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引用次数: 0

Evaluation of the effect of kefir supplementation on inflammatory markers and clinical and hematological indices in COVID-19 patients; a randomized double-blined clinical trial 评估克菲尔补充剂对 COVID-19 患者炎症指标以及临床和血液学指标的影响；随机双盲临床试验

IF 1.7 Q2 Medicine

Advances in integrative medicine

Pub Date : 2024-03-01 DOI: 10.1016/j.aimed.2023.10.006

Ramin Gooruee , Naseh Pahlavani , Vahid Hadi , Saeid Hadi

Background

The aim of the present study was to evaluation the impacts of kefir intake, as a popular traditional probiotic product on the immune response and the recovery process of COVID-19 patients admitted to the hospital.

Methods

We conducted a double-blind randomized controlled trial on 100 COVID-19 patients selected from Emam Reza Hospital between February 9, 2022, and March 9, 2022. In the intervention group, participants received kefir grains (2–10 %) to milk twice a day (250 ccs each time) for two weeks. Clinical outcomes such as fever, pain, gastrointestinal symptoms, and dyspnea were collected at the beginning and end of the study using a checklist prepared by the research team. Also, each group measured inflammatory indices (ESR & CRP) and hematological factors before and after the intervention.

Results

The mean age of participants was 47.06 ± 8.90 years. WBC before (p = 0.001), neutrophil before (p = 0.001), lymphocyte before (p = 0.000) and after (p = 0.001) the intervention, hemoglobin before (p = 0.001) and after (p = 0.001) the intervention, CRP before (0.001), ESR after (p = 0.011), and oxygen saturation after (p = 0.001) the intervention had statistically significant differences between the intervention and control groups (p < 0.05).

Conclusion

Overall, two weeks of kefir intakes in COVID-19 patients had beneficial effects on ESR, WBC count, and Oxygen saturation levels. However, this probiotic product did not influence other evaluated indices including CRP and Hemoglobin in COVID-19 patients. More studies are required to clarify this topic.

背景本研究的目的是评估摄入克菲尔这种流行的传统益生菌产品对入院的 COVID-19 患者的免疫反应和恢复过程的影响。方法我们在 2022 年 2 月 9 日至 2022 年 3 月 9 日期间对 Emam Reza 医院选取的 100 名 COVID-19 患者进行了双盲随机对照试验。在干预组中，参与者在牛奶中加入克菲尔颗粒（2-10%），每天两次（每次 250 毫升），持续两周。在研究开始和结束时，使用研究小组准备的检查表收集发烧、疼痛、胃肠道症状和呼吸困难等临床结果。此外，各组还在干预前后测量了炎症指数（ESR & CRP）和血液学因子。干预前的白细胞（p = 0.001）、干预前的中性粒细胞（p = 0.001）、干预前的淋巴细胞（p = 0.000）和干预后的淋巴细胞（p = 0.001）、干预前的血红蛋白（p = 0.001）和干预后的血红蛋白（p = 0.001）、干预前的 CRP（0.001）、干预后的血沉（p = 0.011）和干预后的血氧饱和度（p = 0.001）干预组和对照组之间有统计学意义的差异（p <0.05）。结论总的来说，COVID-19 患者摄入两周的开菲尔对血沉、白细胞计数和血氧饱和度水平有好处。然而，这种益生菌产品并不影响 COVID-19 患者的其他评估指标，包括 CRP 和血红蛋白。要弄清这个问题，还需要更多的研究。

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引用次数: 0

A pilot study to evaluate the potential therapeutic effect of hydrogen-water bathing on atopic dermatitis in humans 评估氢水沐浴对人类特应性皮炎潜在治疗效果的试点研究

IF 1.7 Q2 Medicine

Advances in integrative medicine

Pub Date : 2024-03-01 DOI: 10.1016/j.aimed.2023.10.003

Ailing Hu , Takuji Yamaguchi , Masahiro Tabuchi , Yasushi Ikarashi , Akio Mizushima , Hiroyuki Kobayashi

Background

Hydrogen molecules, which have excellent antioxidant and anti-inflammatory effects, are absorbed through the skin and spread hematogenously throughout the body. Hydrogen-water bathing (HWB) is expected to be effective against atopic dermatitis (AD); however, its usefulness remains controversial in humans.

Objective

This study aimed to determine whether HWB has the potential to have a therapeutic effect in a pilot study conducted on six patients with AD.

Methods

AD severity was assessed based on the itching intensity per the visual analog scales (VAS) and the transepidermal water loss (TEWL) values of the lesions, in addition to macroscopic observations.

Results

HWB for eight weeks ameliorated the severity of rashes and increased TEWL levels in the trunk/limb areas that could be completely immersed in the bathwater, resulting in ameliorations in severe itching. The specificity of its therapeutic effect was further investigated in one patient who first underwent HWB for four weeks, discontinued it for two weeks, and resumed it for another four weeks. The rashes on the trunk/limb areas visibly improved after four weeks of HWB but worsened again after it was stopped for two weeks, only to improve again after the resumption of HWB for four weeks. The VAS and TEWL values also showed changes that reflected the skin condition.

Conclusion

These results suggest that HWB may be useful in the treatment of AD. To conclude the effectiveness of HWB for AD, it needs to be supported by randomized controlled trials with larger sample sizes and longer study durations in the future.

背景氢分子具有出色的抗氧化和消炎作用，可通过皮肤吸收并以血源性方式扩散到全身。本研究旨在通过对六名特应性皮炎（AD）患者进行试验性研究，确定氢水浴（HWB）是否具有潜在的治疗效果。除了宏观观察外，还根据视觉模拟量表（VAS）的瘙痒强度和皮损的经表皮失水（TEWL）值来评估AD的严重程度。结果连续八周的浴后水浴改善了皮疹的严重程度，提高了可完全浸泡在浴水中的躯干/肢体区域的TEWL水平，从而改善了严重瘙痒。一名患者先接受了四周的 HWB 治疗，停用两周后又继续接受了四周的 HWB 治疗，我们对其治疗效果的特异性进行了进一步研究。接受 HWB 治疗四周后，躯干/肢体部位的皮疹明显好转，但停药两周后皮疹再次恶化，恢复 HWB 治疗四周后皮疹再次好转。VAS 和 TEWL 值也显示出反映皮肤状况的变化。要断定 HWB 对注意力缺失症的疗效，未来还需要样本量更大、研究持续时间更长的随机对照试验的支持。

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引用次数: 0

Conversations about cannabis: the supply process in Australia 关于大麻的对话：澳大利亚的供应过程

IF 1.7 Q2 Medicine

Advances in integrative medicine

Pub Date : 2024-01-01 DOI: 10.1016/j.aimed.2024.01.001

Katherine Cheng, Joanna Harnett, Sharon Davis, Lorraine Smith

引用次数: 0

The clinical efficacy and safety of Ginkgo biloba in vertigo patients: A meta-analysis 银杏叶治疗眩晕患者的临床疗效和安全性:一项meta分析

Q2 Medicine

Advances in integrative medicine

Pub Date : 2023-10-01 DOI: 10.1016/j.aimed.2023.10.001

Xiang Gao, Yan Cheng, Fangyuan Liu, Xiaozhen Han, Chuanliang Liu

引用次数: 0

Evaluating the Barriers to the Utilization of Complementary and Alternative Medicine (CAM) in the United States: An Exploratory Study 评估美国补充和替代医学(CAM)使用的障碍:一项探索性研究

Q2 Medicine

Advances in integrative medicine

Pub Date : 2023-10-01 DOI: 10.1016/j.aimed.2023.10.002

Anwesa Chatterjee

The utilization of certain forms of complementary and alternative medicine (CAM) is prevalent among adults in the United States. While researchers have extensively studied the factors influencing CAM use in Western countries, significant barriers to its adoption remain. This paper draws attention to the obstacles faced by individuals in their journey to using CAM. Qualitative interviews were conducted with 21 patients who had turned to CAM for managing a chronic illness/condition. These in-depth, face-to-face interviews occurred in Miami, USA, during 2014-15. The sampling, data collection, and analysis processes of this study adhered to the principles outlined in Charmaz’s constructivist grounded theory approach. From the data, three central barriers to CAM utilization in the US emerged: 1) Financial barriers: A significant portion of CAM treatments is not covered by insurance, making them cost-prohibitive for many. 2) Skepticism and discouragement: Both conventional medical practitioners and a segment of the public exhibited a noticeable trend towards discouraging CAM use. 3) Evaluation challenges: Patients expressed difficulty in assessing the efficacy and benefits of various CAM treatments compared to their costs. Despite the widespread interest in and use of CAM in the US, numerous barriers hinder its broader integration into mainstream healthcare. These obstacles not only restrict healthcare choices for the general public but also appear to favor a select demographic, potentially based on income and availability of information.

在美国，某些形式的补充和替代医学(CAM)的使用在成年人中很普遍。虽然研究人员广泛研究了西方国家影响辅助医学使用的因素，但采用辅助医学仍然存在重大障碍。本文关注了个人在使用CAM的过程中所面临的障碍。对21名因慢性疾病/病症而求助于CAM的患者进行了定性访谈。这些深入的面对面访谈于2014- 2015年在美国迈阿密进行。本研究的抽样、数据收集和分析过程遵循Charmaz的建构主义扎根理论方法中概述的原则。从数据中可以看出，在美国使用辅助医学的三个主要障碍是:1)经济障碍:很大一部分辅助医学治疗不在保险范围内，这使得许多人的费用过高。2)怀疑和气馁:传统医生和一部分公众都表现出不鼓励使用辅助医学的明显趋势。3)评估挑战:患者表示在评估各种辅助替代疗法的疗效和收益与成本相比时存在困难。尽管CAM在美国有广泛的兴趣和使用，但许多障碍阻碍了它更广泛地融入主流医疗保健。这些障碍不仅限制了一般公众的医疗保健选择，而且似乎有利于特定人群，这可能是基于收入和信息的可用性。

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引用次数: 0