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Protective action in the workplace in the time of COVID-19: The role of worker representation COVID-19 时代的工作场所保护行动:工人代表的作用。
IF 3.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-07 DOI: 10.1002/ajim.23578
Laia Ollé-Espluga PhD, Raúl Payá Castiblanque PhD, Clara Llorens-Serrano PhD, Laura Esteve-Matalí PhD, Albert Navarro-Giné PhD

Background

This study addresses the contribution of worker representation to health and safety in the pandemic context. To do so, we examine whether the self-reported presence of representatives in workplaces is associated with the implementation of anti-COVID-19 protective action and with which type of measures their existence is most strongly associated (individual, collective or organizational). The article also explores how the presence of worker representatives and anti-COVID-19 protective measures are distributed according to workers' socio-professional characteristics and company features.

Methods

This is a cross-sectional study based on an online survey conducted in Spain (n = 19,452 workers). Multiple Correspondence Analysis was used for the multivariate description while the association between worker representation and protective measures was assessed by robust Poisson regressions.

Results

The maps resulting from the Multiple Correspondence Analysis allow for the identification of patterns of inequalities in protection, with a clear occupational social class divide. The regression models show that protective measures are applied more frequently where worker representatives exist, this association being particularly strong in relation to organizational measures.

Conclusions

The presence of worker representation is systematically associated with a greater presence of protective measures, which could have implications for the reduction of social inequalities resulting from labor-management practices.

背景:本研究探讨了大流行病背景下工人代表对健康和安全的贡献。为此,我们研究了工作场所中自我报告的代表的存在是否与反 COVID-19 保护措施的实施有关,以及他们的存在与哪类措施(个人、集体或组织)关系最为密切。文章还探讨了工人代表的存在和反 COVID-19 保护措施是如何根据工人的社会职业特征和公司特点进行分布的:这是一项横断面研究,基于在西班牙进行的在线调查(n = 19,452 名工人)。采用多重对应分析法进行多变量描述,同时通过稳健的泊松回归评估工人代表性与保护措施之间的关联:结果:通过多重对应分析得出的地图可以确定保护措施的不平等模式,其中存在明显的职业社会阶层鸿沟。回归模型显示,在有工人代表的地方,采取保护措施的频率更高,这种关联在组织措施方面尤为明显:结论:工人代表的存在与更多保护措施的存在有系统性的联系,这可能对减少劳资双方做法造成的社会不平等产生影响。
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引用次数: 0
Occupational lung cancer screening: A Collegium Ramazzini statement 职业性肺癌筛查:拉马齐尼学院声明。
IF 3.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-05 DOI: 10.1002/ajim.23572
Steven Markowitz MD, DrPH, Knut Ringen DrPH, MHA, MPH, John M. Dement PhD, Kurt Straif MD, PhD, MPH, L. Christine Oliver MD, MPH, MS, Eduardo Algranti MD, MSc, PhD, Dennis Nowak MD, Rodney Ehrlich MBCHB, DOH, FCPHM(SA)(Occ Med), PhD, Melissa A. McDiarmid MD, MPH, DABT, Albert Miller MD, Collegium Ramazzini
<p>Lung cancer is the most common cause of death from cancer in the world. It is also the most common lethal work-related cancer. After tobacco smoking, occupational exposures present the most frequent specific cause of lung cancer that is amenable to intervention.</p><p>Early detection and treatment can identify and cure primary lung cancer. Randomized controlled trials have demonstrated the efficacy of low dose computed tomography (LDCT) screening among persons at high risk of lung cancer. Guidelines for determining eligibility for LDCT screening have been established for the general population but have largely neglected those for whom occupational exposure to lung carcinogens is a risk factor.</p><p>The Collegium recommends that persons at risk for lung cancer from occupational exposures be offered annual LDCT if their cumulative risk of lung cancer approximates the level of risk endorsed by the guidelines promulgated by the United States Preventive Services Task Force (USPSTF) in 2021 and the National Comprehensive Cancer Network (NCCN) in the United States in 2021. At present, these agencies recommend screening for people aged 50 and over who have smoked at least 20 pack-years of cigarettes. The Collegium recommends that additional lung cancer risk factors, including exposure to known or suspected occupational and environmental lung carcinogens; family history of lung cancer (especially among first degree relatives and relatives <60 years of age); a personal history of chronic obstructive lung disease, pneumoconiosis, or pulmonary fibrosis; or a personal history of cancer (excluding skin cancer) be considered as part of the risk assessment for eligibility determination for lung cancer screening. Latency, or the period of time since initial occupational exposure (e.g., >15 years) is another factor that should be considered. If the presence of these additional risk factors, in combination with age and smoking history, is associated with a level of risk that meets or exceeds the level of risk identified by the USPSTF and NCCN, then an annual low dose chest CT for lung cancer screening should be offered. We do not favor a specific age cut-off at which to end screening, but we recognize that only persons who are sufficiently healthy and have sufficient life expectancy to undergo diagnostic work-up and potentially curative treatment should be offered screening for lung cancer. In view of the rising risk of occupational lung cancer over time and the potential or actual interaction between occupational lung carcinogens and cigarette smoking even after quitting, screening programs may choose to screen workers with occupational lung cancer risk for prolonged periods after they have quit smoking cigarettes. The Collegium acknowledges that there are uncertainties and assumptions entailed in this approach and that risk assessment for individual workers necessitates application of significant professional judgement. We encourage the implementation o
肺癌是世界上最常见的癌症死因。它也是最常见的与工作有关的致命癌症。继吸烟之后,职业暴露是导致肺癌的最常见的可干预的特定原因。随机对照试验已经证明,在肺癌高危人群中进行低剂量计算机断层扫描(LDCT)筛查是有效的。该委员会建议,如果因职业暴露而罹患肺癌的高危人群的肺癌累积风险接近美国预防服务工作组(USPSTF)和美国国家综合癌症网络(NCCN)分别于 2021 年和 2021 年颁布的指南所认可的风险水平,则应每年进行低剂量计算机断层扫描筛查。目前,这些机构建议对吸烟至少 20 包年的 50 岁及以上人群进行筛查。该委员会建议在确定肺癌筛查资格的风险评估中考虑其他肺癌风险因素,包括暴露于已知或可疑的职业和环境肺致癌物;肺癌家族史(尤其是一级亲属和 60 岁以上亲属);慢性阻塞性肺病、尘肺或肺纤维化的个人病史;或个人癌症病史(皮肤癌除外)。另一个应考虑的因素是潜伏期,或自初次职业暴露以来的时间(如 15 年)。如果存在这些额外的风险因素,再加上年龄和吸烟史,其风险水平达到或超过 USPSTF 和 NCCN 确定的风险水平,则应每年进行一次低剂量胸部 CT 肺癌筛查。我们不赞成以特定的年龄为分界线来终止筛查,但我们认识到,只有那些身体健康、有足够的预期寿命来接受诊断工作和可能治愈的治疗的人,才应接受肺癌筛查。鉴于职业性肺癌的风险随着时间的推移而上升,以及职业性肺致癌物与戒烟后吸烟之间潜在或实际的相互作用,筛查计划可能会选择在有职业性肺癌风险的工人戒烟后对其进行长期筛查。专家团承认,这种方法存在不确定性和假设,对个体劳动者的风险评估需要运用大量的专业判断。我们鼓励实施组织良好的筛查计划,以进一步了解最佳职业包容性肺癌筛查策略。有已知或疑似肺致癌物暴露史的工人,或从事已知会增加肺癌风险的职业/行业或工作任务的工人,是肺癌筛查的目标人群。肺癌致癌物的重要例子包括石棉、二氧化硅、柴油机废气、焊接烟雾、特定金属和辐射。本委员会呼吁职业健康和医疗专业人员及利益相关者(政府、雇主、保险公司和工会)确定肺癌风险过高的工人群体,促进肺癌筛查,并制定和支持组织良好的计划,在这些人群中开展此类筛查。通过环境控制消除或尽量减少工作场所的肺致癌物暴露是预防肺癌的关键,而肺癌筛查则是减少工作场所肺致癌物暴露导致的死亡和致残疾病的重要辅助干预措施。所有作者都对声明进行了编辑,并贡献了自己的智慧。所有作者均已批准本稿件的提交版本,并同意对工作的所有方面负责,确保与工作任何部分的准确性或完整性有关的问题得到适当的调查和解决。拉马齐尼学会对《声明》进行了同行评审,其成员批准了《声明》的最终版本。拉马齐尼学会是一个国际科学学会,研究职业与环境医学中的关键问题,以期采取行动预防疾病,促进健康。
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引用次数: 0
COVID-19 mortality among Massachusetts workers and the association with telework ability, 2020 2020 年马萨诸塞州工人 COVID-19 死亡率及其与远程工作能力的关系。
IF 3.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-02 DOI: 10.1002/ajim.23579
Kathleen Fitzsimmons PhD, MPH, Malena Hood MPH, Kathleen Grattan MPH, James Laing, Emily Sparer-Fine ScD, MS

Background

Working outside the home put some workers at risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure and might partly explain elevated coronavirus disease 2019 (COVID-19) mortality rates in the first months of the pandemic in certain groups of Massachusetts workers. To further investigate this premise, we examined COVID-19 mortality among Massachusetts workers, with a specific focus on telework ability based on occupation.

Methods

COVID-19-associated deaths between January 1 and December 31, 2020 among Massachusetts residents aged 18–64 years were analyzed. Deaths were categorized into occupation-based quadrants (Q) of telework ability. Age-adjusted rates were calculated by key demographics, industry, occupation, and telework quadrant using American Community Survey workforce estimates as denominators. Rate ratios (RRs) and 95% confidence intervals comparing rates for quadrants with workers unlikely able to telework (Q2, Q3, Q4) to that among those likely able to telework (Q1) were calculated.

Results

The overall age-adjusted COVID-19-associated mortality rate was 26.4 deaths per 100,000 workers. Workers who were male, Black non-Hispanic, Hispanic, born outside the US, and with lower than a high school education level experienced the highest rates among their respective demographic groups. The rate varied by industry, occupation and telework quadrant. RRs comparing Q2, Q3, and Q4 to Q1 were 0.99 (95% confidence interval [CI]: 0.8−1.2), 3.2 (95% CI: 2.6−3.8) and 2.5 (95% CI: 2.0−3.0), respectively.

Conclusion

Findings suggest a positive association between working on-site and COVID-19-associated mortality. Work-related factors likely contributed to COVID-19 among Massachusetts workers and should be considered in future studies of COVID-19 and similar diseases.

背景:外出工作使一些工人面临接触严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)的风险,这可能是大流行头几个月马萨诸塞州某些工人群体冠状病毒病 2019(COVID-19)死亡率升高的部分原因。为了进一步研究这一前提,我们对马萨诸塞州工人的 COVID-19 死亡率进行了研究,特别关注基于职业的远程工作能力:分析了 2020 年 1 月 1 日至 12 月 31 日期间马萨诸塞州 18-64 岁居民中与 COVID-19 相关的死亡人数。死亡人数按远程工作能力的职业象限 (Q) 进行分类。以美国社区调查劳动力估计值为分母,按主要人口统计、行业、职业和远程工作象限计算年龄调整率。计算了不可能远程工作的工人(Q2、Q3、Q4)与可能远程工作的工人(Q1)的比率比(RRs)和 95% 的置信区间:经年龄调整后,与 COVID-19 相关的总死亡率为每 10 万名工人中有 26.4 人死亡。男性、非西班牙裔黑人、西班牙裔、在美国境外出生以及高中以下学历的工人在各自人口群体中的死亡率最高。该比率因行业、职业和远程工作象限而异。第二、第三和第四季度与第一季度相比,RR 分别为 0.99(95% 置信区间[CI]:0.8-1.2)、3.2(95% CI:2.6-3.8)和 2.5(95% CI:2.0-3.0):研究结果表明,现场工作与 COVID-19 相关死亡率之间存在正相关。在马萨诸塞州的工人中,与工作有关的因素可能是导致 COVID-19 的原因之一,在今后对 COVID-19 和类似疾病的研究中应加以考虑。
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引用次数: 0
“…full of opportunities, but not for everyone”: A narrative inquiry into mechanisms of labor market inequity among precariously employed gay, bisexual, and queer men "......充满机会,但并非人人都有":对就业不稳定的男同性恋者、双性恋者和同性恋者在劳动力市场上的不平等机制的叙事调查。
IF 3.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-02-20 DOI: 10.1002/ajim.23574
David J. Kinitz PhD, MSW, Lori E. Ross PhD, Ellen MacEachen PhD, Charles Fehr MA, Dionne Gesink PhD

Background

This study brings lesbian, gay, bisexual, transgender (trans), and queer (LGBTQ+) populations into scholarly discourse related to precarious employment through a political economy of queer struggle.

Methods

Drawing on narrative inquiry, 20 gay, bisexual, and queer men shared stories of precarious employment that were analyzed using Polkinghorne's narrative analysis.

Results

Results tell an overarching narrative in three parts that follow the trajectory of participants' early life experiences, entering the labor market and being precariously employed. Part 1: Devaluation of LGBTQ+ identities and adverse life experiences impacted participants' abilities to plan their careers and complete postsecondary education. Part 2: Participants experienced restricted opportunities due to safety concerns and learned to navigate white, cis, straight, Canadian ideals that are valued in the labor market. Part 3: Participants were without protections to respond to hostile treatment for fear of losing their employment.

Conclusions

These stories of precarious employment illustrate unique ways that LGBTQ+ people might be particularly susceptible to exploitative labor markets.

背景:本研究通过同性恋斗争的政治经济学,将女同性恋、男同性恋、双性恋、跨性别者(变性人)和同性恋(LGBTQ+)人群纳入与不稳定就业相关的学术讨论中:方法:利用叙事调查,20 名男同性恋、双性恋和同性恋者分享了就业不稳定的故事,并使用波尔金霍恩叙事分析法对这些故事进行了分析:结果:结果将参与者的早期生活经历、进入劳动力市场和就业不稳定的轨迹分为三个部分,讲述了一个总体叙事。第一部分对 LGBTQ+ 身份的贬低和不利的生活经历影响了参与者规划职业生涯和完成中学后教育的能力。第二部分:出于安全考虑,参与者的机会受到了限制,并学会了如何在劳动力市场上树立白人、同性恋、异性恋、加拿大人的理想。第 3 部分:参与者因害怕失去工作而没有保护措施来应对敌意待遇:这些就业不稳定的故事说明了 LGBTQ+ 人士特别容易受到劳动力市场剥削的独特方式。
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引用次数: 0
Acute occupational inhalation injuries—United States, 2011–2022 2011-2022 年美国急性职业吸入伤害情况。
IF 3.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-02-14 DOI: 10.1002/ajim.23573
Nirmala T. Myers PhD, Katelynn E. Dodd MPH, Janet M. Hale BS, David J. Blackley DrPh, A. Scott Laney PhD, Noemi B. Hall PhD

Background

Inhalation injuries due to acute occupational exposures to chemicals are preventable. National surveillance of acute inhalation exposures is limited. This study identified the most common acute inhalation exposure-related incidents by industry sector among US workers.

Methods

To characterize inhalation-related injuries and their exposures during April 2011–March 2022, state and federal records from the Occupational Safety and Health Administration (OSHA) Occupational Safety and Health Information System (OIS) accident database were analyzed. Industry-specific injury, hospitalization, and fatality rates were calculated.

Results

The most frequent acute inhalation incidents investigated by OSHA were caused by inorganic gases (52.9%) such as carbon monoxide (CO) or acids, bases, and oxidizing chemical agents (12.9%) such as anhydrous ammonia. The largest number of fatal and nonfatal injuries were reported in the manufacturing (28.6%) and construction (17.2%) sectors.

Conclusions

Workers were affected by acute inhalation exposures in most industries. Using this surveillance, employers can recognize frequently-occurring preventable acute inhalation exposures by industry, such as inorganic gases in the manufacturing sector, and implement prevention measures. Training of workers on exposure characteristics and limits, adverse health effects, and use of protective equipment by exposure agent can prevent inhalation injuries.

背景:急性职业接触化学品导致的吸入伤害是可以预防的。对急性吸入接触的全国性监测非常有限。本研究按行业领域确定了美国工人中最常见的急性吸入接触相关事故:为了描述 2011 年 4 月至 2022 年 3 月期间与吸入有关的伤害及其接触情况,我们分析了职业安全与健康管理局 (OSHA) 职业安全与健康信息系统 (OIS) 事故数据库中的州和联邦记录。计算了特定行业的受伤率、住院率和死亡率:OSHA 调查的最常见的急性吸入事故是由无机气体(52.9%)如一氧化碳(CO)或酸、碱和氧化性化学制剂(12.9%)如无水氨引起的。制造业(28.6%)和建筑业(17.2%)报告的致命和非致命工伤最多:大多数行业的工人都受到急性吸入接触的影响。通过此次监测,雇主可以按行业识别出经常发生的可预防的急性吸入接触,如制造业中的无机气体,并实施预防措施。对工人进行有关接触特性和限制、对健康的不利影响以及按接触物使用防护设备的培训,可以预防吸入伤害。
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引用次数: 0
The effect of power stretchers on occupational injury rates in an urban emergency medical services system 城市紧急医疗服务系统中电动担架对工伤率的影响。
IF 3.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-02-14 DOI: 10.1002/ajim.23571
Rob Pryce CAT(C), PhD, Erin Weldon MD, Neil McDonald ACP, PhD, Ryan Sneath ACP, BN

Background

To examine occupational injury rates in a dual-response emergency medical services (EMS) system before and after implementation of a power-lift stretcher system.

Methods

The seasonally-adjusted occupational injury rate was estimated relative to medical call volume (per 1000 calls) and workers (per 100 FTEs) from 2009 to 2019, and stratified by severity (lost-time, healthcare only), role (EMS, FIRE) and type (patient-handling). Power-lift stretchers were adopted between 2013 and 2015. Preinjury versus postinjury rates were compared using binomial tests. Interrupted time series (ITS) analysis was used to estimate the trend and change in injuries related to patient-handling, with occupational illnesses serving as control.

Results

Binomial tests revealed varied results, with reductions in the injury rate per 1000 calls (−14.0%) and increases in the rate per 100 FTEs (+14.1%); rates also differed by EMS role and injury severity. ITS analysis demonstrated substantial reductions in patient-handling injuries following implementation of power-lift stretchers, both in the injury rate per 1000 calls (−50.4%) and per 100 FTEs (−46.6%), specifically among individuals deployed on the ambulance. Injury rates were slightly elevated during the winter months (+0.8 per 100 FTEs) and lower during spring (−0.5 per 100 FTEs).

Conclusions

These results support the implementation of power-lift stretchers for injury prevention in EMS systems and demonstrate advantages of ITS analysis when data span long preintervention and postintervention periods.

背景:研究一个双响应紧急医疗服务(EMS)系统在实施电动担架系统前后的工伤率:研究双响应紧急医疗服务(EMS)系统在实施电动升降担架系统前后的工伤率:方法:2009 年至 2019 年期间,根据医疗呼叫量(每 1000 次呼叫)和工人(每 100 名全职员工)估算了经季节性调整的职业伤害率,并按严重程度(损失工时、仅医疗保健)、角色(EMS、FIRE)和类型(病人搬运)进行了分层。2013 年至 2015 年期间采用了电动升降担架。使用二项检验比较了受伤前与受伤后的比率。使用间断时间序列(ITS)分析来估计与病人搬运有关的伤害趋势和变化,并以职业病作为对照:二项检验显示了不同的结果,每 1000 次呼叫的受伤率有所下降(-14.0%),而每 100 个全职急救人员的受伤率则有所上升(+14.1%);急救服务角色和受伤严重程度不同,受伤率也不同。ITS 分析表明,在使用电动升降担架后,病人搬运伤害大幅减少,每 1000 次呼叫的伤害率(-50.4%)和每 100 名全职急救人员的伤害率(-46.6%)均有所下降,特别是在救护车上的人员中。受伤率在冬季略有上升(每 100 个全职急救人员 +0.8),而在春季则有所下降(每 100 个全职急救人员 -0.5):这些结果支持在急救系统中使用动力提升担架来预防伤害,并证明了在干预前和干预后数据跨度较长的情况下进行 ITS 分析的优势。
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引用次数: 0
Cover Image: Volume 67 Issue 3 封面图片:第 67 卷第 3 期
IF 3.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-02-13 DOI: 10.1002/ajim.23575
Judith A. Crawford PhD, Soma Sanyal MD, Bryan R. Burnett MS, Stephen L. Wiesenfeld MD, Jerrold L. Abraham MD

Cover Caption: The cover image is based on the Research Article Accelerated silicosis in sandblasters: Pathology, mineralogy, and clinical correlates by Judith A. Crawford PhD et al., https://doi.org/10.1002/ajim.23561.

封面标题:封面图片根据 Judith A. Crawford 博士等人的研究文章《喷砂机中的加速矽肺病:病理学、矿物学和临床相关性》,作者:Judith A. Crawford 博士等,https://doi.org/10.1002/ajim.23561。
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引用次数: 0
Mortality and cancer incidence in perfluorooctanesulfonyl fluoride production workers 全氟辛基磺酰氟生产工人的死亡率和癌症发病率。
IF 3.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-02-12 DOI: 10.1002/ajim.23568
Bruce H. Alexander PhD, Andrew Ryan MS, Timothy R. Church PhD, Hyun Kim ScD, Geary W. Olsen DVM, PhD, Perry W. Logan PhD

Background

Exposure to per- and polyfluoroalkyl substances (PFAS) has been associated with several health outcomes, though few occupationally-exposed populations have been studied. We evaluated mortality and cancer incidence in a cohort of perfluorooctanesulfonyl fluoride-based specialty chemical manufacturing workers.

Methods

The cohort included any employee who ever worked at the facility from 1961 to 2010 (N = 4045), with a primary interest in those who had 365 cumulative days of employment (N = 2659). Vital status and mortality records were obtained through 2014 and the cohort was linked to state cancer registries to obtain incident cancer cases from 1995 to 2014. Cumulative exposure was derived from a comprehensive exposure reconstruction that estimated job-specific perfluorooctanesulfonate (PFOS)-equivalents (mg/m3) exposure. Overall and exposure-specific standardized mortality ratios (SMR) were estimated in reference to the US population. Hazard ratios (HRs) and 95% confidence interval (CI) for cumulative PFOS-equivalent exposure (log2 transformed) were estimated within the cohort for specific causes of death and incident cancers using a time-dependent Cox model.

Results

Death rates were lower than expected except for cerebrovascular disease (SMR = 2.42, 95% CI = 1.25–4.22) and bladder cancer (SMR = 3.91, 95% CI = 1.07–10.02) in the highest exposure quartile. Within the cohort, the incidence of bladder, colorectal, and pancreatic cancer were positively associated with exposure, however except for lung cancer (HR = 1.05, 95% CI = 1.00–1.11) the CIs did not exclude an HR of 1.

Conclusions

This study provides some evidence that occupational exposure to PFOS is associated with bladder and lung cancers and with cerebrovascular disease.

背景:接触全氟和多氟烷基物质(PFAS)与多种健康后果有关,但很少对职业接触人群进行研究。我们评估了一批以全氟辛基磺酰氟为基础的特种化学品生产工人的死亡率和癌症发病率:研究对象包括 1961 年至 2010 年期间在该工厂工作过的所有员工(N = 4045),主要关注那些累计工作天数达到 365 天的员工(N = 2659)。我们获得了截至 2014 年的生命体征和死亡记录,并将队列与州癌症登记处进行了链接,以获得 1995 年至 2014 年的癌症病例。累积暴露量来自于全面的暴露重建,该重建估算了特定工作的全氟辛烷磺酸(PFOS)当量(mg/m3)暴露量。参照美国人口估算了总体和特定暴露的标准化死亡率(SMR)。使用时间依赖性 Cox 模型估算了队列中特定死因和癌症发病的累积全氟辛烷磺酸当量暴露量(对数 2 转换)的危险比(HRs)和 95% 的置信区间(CI):除最高暴露四分位数的脑血管疾病(SMR = 2.42,95% CI = 1.25-4.22)和膀胱癌(SMR = 3.91,95% CI = 1.07-10.02)外,死亡率均低于预期。在队列中,膀胱癌、结肠直肠癌和胰腺癌的发病率与暴露呈正相关,但除肺癌(HR = 1.05,95% CI = 1.00-1.11)外,CIs 均不排除 HR 为 1.0 的结论:本研究提供了一些证据,表明职业性接触全氟辛烷磺酸与膀胱癌、肺癌和脑血管疾病有关。
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引用次数: 0
Work–rest regimens for work in hot environments: A scoping review 高温环境下的工作-休息方案:范围审查。
IF 3.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-02-12 DOI: 10.1002/ajim.23569
Thomas A. Deshayes PhD, Hsen Hsouna PhD, Mounir A. A. Braham MSc, Denis Arvisais MSI, Benjamin Pageaux PhD, Capucine Ouellet ROH, Ollie Jay PhD, Fabien D. Maso PhD, Mickael Begon PhD, Alireza Saidi PhD, Philippe Gendron PhD, Daniel Gagnon PhD

Background

To limit exposures to occupational heat stress, leading occupational health and safety organizations recommend work–rest regimens to prevent core temperature from exceeding 38°C or increasing by ≥1°C. This scoping review aims to map existing knowledge of the effects of work–rest regimens in hot environments and to propose recommendations for future research based on identified gaps.

Methods

We performed a search of 10 databases to retrieve studies focused on work–rest regimens under hot conditions.

Results

Forty-nine articles were included, of which 35 were experimental studies. Most studies were conducted in laboratory settings, in North America (71%), on healthy young adults, with 94% of the 642 participants being males. Most studies (66%) employed a protocol duration ≤240 min (222 ± 162 min, range: 37–660) and the time-weighted average wet-bulb globe temperature was 27 ± 4°C (range: 18–34). The work–rest regimens implemented were those proposed by the American Conference of Governmental and Industrial Hygiene (20%), National Institute of Occupational Safety and Health (11%), or the Australian Army (3%). The remaining studies (66%) did not mention how the work–rest regimens were derived. Most studies (89%) focused on physical tasks only. Most studies (94%) reported core temperature, whereas only 22% reported physical and/or mental performance outcomes, respectively. Of the 35 experimental studies included, 77% indicated that core temperature exceeded 38°C.

Conclusions

Although work–rest regimens are widely used, few studies have investigated their physiological effectiveness. These studies were mainly short in duration, involved mostly healthy young males, and rarely considered the effect of work–rest regimens beyond heat strain during physical exertion.

背景:为了限制职业热应激暴露,主要的职业健康与安全组织建议采取工作-休息方案,以防止核心体温超过 38°C 或升高≥1°C。本范围综述旨在了解有关高温环境下工作-休息方案影响的现有知识,并根据已发现的差距提出未来研究建议:方法:我们对 10 个数据库进行了搜索,以检索有关高温条件下工作-休息方案的研究:结果:共收录了 49 篇文章,其中 35 篇为实验研究。大多数研究都是在北美的实验室环境中进行的(71%),对象是健康的年轻人,642 名参与者中有 94% 是男性。大多数研究(66%)采用的方案持续时间不超过 240 分钟(222 ± 162 分钟,范围:37-660),时间加权平均湿球温度为 27 ± 4°C (范围:18-34)。所实施的工作-休息方案是由美国政府和工业卫生会议(20%)、美国国家职业安全与健康研究所(11%)或澳大利亚军队(3%)提出的。其余的研究(66%)没有提及工作-休息方案是如何得出的。大多数研究(89%)只关注体力任务。大多数研究(94%)报告了核心体温,而只有 22% 的研究分别报告了身体和/或精神表现的结果。在纳入的 35 项实验研究中,77% 的研究表明核心温度超过 38°C:尽管工作-休息方案被广泛使用,但很少有研究对其生理效果进行调查。这些研究主要持续时间较短,主要涉及健康的年轻男性,并且很少考虑工休方案在体力消耗时的热应变之外的影响。
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引用次数: 0
Risk of subsequent SARS-CoV-2 infection among vaccinated employees with or without hybrid immunity acquired early in the Omicron-predominant era of the COVID-19 pandemic 在 COVID-19 大流行的 Omicron 主导时代早期获得或未获得混合免疫力的已接种疫苗的员工随后感染 SARS-CoV-2 的风险。
IF 3.5 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-02-05 DOI: 10.1002/ajim.23570
Mark A. Jacobson MD, Paul D. Blanc MD, MSPH, Jacqueline Tulsky MD, Monica Tilly MD, MPH, Raymond Meister MD, Will Huen MD, MS, MPH, James E. McNicholas Jr. DO, MPH, FACP

Background

Hybrid immunity, from COVID-19 vaccination followed by SARS-CoV-2 infection acquired after its Omicron variant began predominating, has provided greater protection than vaccination alone against subsequent infection over 1–3 months of observation. Its longer-term protection is unknown.

Methods

We conducted a retrospective cohort study of COVID-19 case incidence among healthcare personnel (HCP) mandated to be vaccinated and report on COVID-19-associated symptoms, high-risk exposures, or known-positive test results to an employee health hotline. We compared cases with hybrid immunity, defined as incident COVID-19 during the first 6 weeks of Omicron-variant predominance (run-in period), to those with immunity from vaccination alone during the run-in period. Time until COVID-19 infection over 13 subsequent months (observation period) was analyzed by standard survival analysis.

Results

Of 5867 employees, 641 (10.9%, 95% confidence interval [CI]: 10.1%–11.8%) acquired hybrid immunity during the run-in period. Of these, 104 (16.2%, 95% CI: 13.5%–19.3%) experienced new SARS-CoV-2 infection during the 13-month observation period, compared to 2177 (41.7%, 95% CI: 40.3%–43.0%) of the 5226 HCP without hybrid immunity. Time until incident infection was shorter among the latter (hazard ratio: 3.09, 95% CI: 2.54–3.78).

Conclusions

In a cohort of vaccinated employees, Omicron-era acquired SARS-CoV-2 hybrid immunity was associated with significantly lower risk of subsequent infection over more than a year of observation—a time period far longer than previously reported and during which three, progressively more resistant, Omicron subvariants became predominant. These findings can inform institutional policy and planning for future COVID-19 additional vaccine dosing requirements for employees, for surveillance programs, and for risk modification efforts.

背景:接种 COVID-19 疫苗后,在其 Omicron 变体开始占主导地位后感染 SARS-CoV-2 可产生混合免疫力,在 1-3 个月的观察期内,混合免疫力比单独接种疫苗对后续感染的保护作用更大。其长期保护效果尚不清楚:我们对必须接种疫苗并向员工健康热线报告 COVID-19 相关症状、高危暴露或已知阳性检测结果的医护人员(HCP)中的 COVID-19 病例发生率进行了一项回顾性队列研究。我们将混合免疫病例(定义为在Omicron变异体占优势的前6周(磨合期)内发生COVID-19事件)与磨合期内仅接种疫苗获得免疫力的病例进行了比较。通过标准生存分析法对随后13个月(观察期)内感染COVID-19的时间进行了分析:在 5867 名员工中,有 641 人(10.9%,95% 置信区间 [CI]:10.1%-11.8%)在磨合期获得了混合免疫力。其中 104 人(16.2%,95% 置信区间:13.5%-19.3%)在 13 个月的观察期内新感染了 SARS-CoV-2,而在 5226 名未获得混合免疫的 HCP 中,有 2177 人(41.7%,95% 置信区间:40.3%-43.0%)新感染了 SARS-CoV-2。后者发生感染的时间更短(危险比:3.09,95% CI:2.54-3.78):在一组接种过疫苗的员工中,奥米克龙时代获得的 SARS-CoV-2 混合免疫与一年多的观察期中较低的后续感染风险有关--这段时间远远长于之前的报道,在此期间,三种抗药性逐渐增强的奥米克龙亚变体成为主要变体。这些研究结果可以为机构政策和规划提供参考,以便在未来对员工、监控项目和风险调整工作提出 COVID-19 额外疫苗剂量要求。
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引用次数: 0
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American journal of industrial medicine
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