Current Developments in Nutrition最新文献_第3页

Associations Between Micronutrient Status, Hormones, and Immune Status During Pregnancy and Child Growth in Rural Bangladesh: A Prospective Cohort Study 孟加拉国农村怀孕期间微量营养素状况、激素和免疫状况与儿童生长之间的关系：一项前瞻性队列研究

IF 3.2 Q2 NUTRITION & DIETETICS

Current Developments in Nutrition

Pub Date : 2025-12-01 DOI: 10.1016/j.cdnut.2025.107596

Belinda Chen , Andrew N Mertens , Chih-Hsien Lin , Sophia T Tan , Farheen Jamshed , Diego Figueroa , Caitlin Hemlock , Zachary Butzin-Dozier , Lia CH Fernald , Christine P Stewart , Alan E Hubbard , Md Ziaur Rahman , Shahjahan Ali , Benjamin F Arnold , Firdaus S Dhabhar , Douglas A Granger , Mahbubur Rahman , Stephen P Luby , John M Colford Jr. , Audrie Lin

Background

Poor growth in early childhood is associated with increased mortality, impaired cognitive development, and reduced adult economic productivity, which may result in higher risks of social immobility and intergenerational poverty.

Objective

We aimed to evaluate whether maternal hormones, immune status, and micronutrient status during all trimesters of pregnancy were associated with child growth outcomes in the first two years after birth.

Methods

This observational study used data collected from the WASH Benefits trial in rural Bangladesh to examine associations between maternal hormones [plasma cortisol, estriol], immune status [C-reactive protein, α-1-acid glycoprotein (AGP), cytokine sum score], and micronutrient status [vitamin D (25-hydroxy-D [25(OH)D]), ferritin, soluble transferrin receptor, retinol binding protein (RBP)] during pregnancy and subsequent measures of child growth. Length-for-age z-score (LAZ), weight-for-length z-score (WLZ), and insulin-like growth factor 1 (IGF-1) at 3, 14, and 28 mo were measured as the primary outcomes. All outcomes were adjusted for confounding variables, and the P values were adjusted using the Benjamini–Hochberg procedure. We used generalized additive models, adjusted for covariates, and reported the mean difference in outcomes between the 25th and 75th percentiles of the exposure distribution.

Results

In the adjusted models of this study (n = 636), at 3 mo of age, maternal AGP and RBP were positively associated with infant WLZ. By 14 mo, higher maternal estriol was linked with higher LAZ, and RBP remained positively associated with WLZ. At 28 mo, maternal estriol showed a negative association with IGF-1, and a higher cytokine sum score was negatively associated with WLZ.

Conclusions

These findings suggest the possible pathways through which maternal biomarkers influence early childhood growth, highlighting the intrauterine environment’s critical role in shaping developmental outcomes.

The parent trial was registered at clinicaltrials.gov (NCT01590095).

儿童早期发育不良与死亡率上升、认知发展受损和成人经济生产力下降有关，这可能导致社会不动和代际贫困的更高风险。目的：我们旨在评估孕期所有三个月的母体激素、免疫状态和微量营养素状态是否与出生后头两年的儿童生长结局相关。方法：本观察性研究使用从孟加拉国农村WASH Benefits试验收集的数据，检查妊娠期间母体激素[血浆皮质醇、雌三醇]、免疫状态[c反应蛋白、α-1-酸性糖蛋白（AGP）、细胞因子总评分]、微量营养素状态[维生素D（25-羟基D [25(OH)D]）、铁蛋白、可溶性转铁蛋白受体、视黄醇结合蛋白（RBP）]和随后儿童生长指标之间的关系。在3、14和28个月时测量长度年龄z分数（LAZ）、体重长度z分数（WLZ）和胰岛素样生长因子1 （IGF-1）作为主要结局。根据混杂变量调整所有结果，并使用Benjamini-Hochberg程序调整P值。我们使用广义加性模型，对协变量进行了调整，并报告了暴露分布的第25和第75百分位之间结果的平均差异。结果本研究调整模型（n = 636）中，3月龄时，母亲AGP和RBP与婴儿WLZ呈正相关。到14个月时，较高的母体雌三醇与较高的LAZ相关，RBP仍与WLZ呈正相关。28月龄时，母体雌三醇与IGF-1呈负相关，较高的细胞因子总和评分与WLZ呈负相关。这些发现提示了母体生物标志物影响儿童早期生长的可能途径，强调了宫内环境在塑造发育结果中的关键作用。母试验已在clinicaltrials.gov注册（NCT01590095）。

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引用次数: 0

Validation Study of Adherence to Daily Multiple Micronutrient Supplementation by Palestine Refugee Women Attending United nations Relief and Works Agency for Palestine Refugees in the Near East Health Clinics in Jordan 参加联合国近东巴勒斯坦难民救济和工程处约旦保健诊所的巴勒斯坦难民妇女坚持每日补充多种微量营养素的验证研究

IF 3.2 Q2 NUTRITION & DIETETICS

Current Developments in Nutrition

Pub Date : 2025-12-01 DOI: 10.1016/j.cdnut.2025.107588

Masako Horino , Luai Al-Khatib , Rami Habash , Tamara Al-Rahahleh , Akihiro Seita , Saifuddin Ahmed , Klaus Kraemer , Kristen M Hurley , Keith P West Jr.

Background

Multiple micronutrient supplementation (MMS) is a new standard of antenatal care emerging in lower-income countries. Assessing adherence, a key implementation outcome, requires validation.

Objectives

Validate antenatal adherence to daily MMS based on recalled tablet days missed during follow-up intervals in UNRWA clinics serving Palestine refugees in Jordan.

Methods

This study was conducted during an implementation trial of antenatal MMS versus standard-of-care iron-folic acid supplementation. In 13 clinics, at registration, pregnant women received daily MMS in 180-count bottles weighing 111 g (bottle with desiccant = 26 g, tablet = 0.47 g). At seven follow-up visits, returning bottles were weighed to nearest gram on digital scales, and recalled tablet days missed were recorded. Tablets removed from bottles, estimated from bottle weight decrements, were regressed on tablets taken, obtained by subtracting tablet days missed from interval lengths. Similar analyses were conducted for cumulative intervals since registration.

Results

Among 9754 registered women, 7608 (78%), 6,208 (63.6%), 4,833 (49.5%), 3,409 (34.9%), 2159 (22.1%), 1063 (10.9%), and 384 (3.9%) completed the first-to-seventh follow-up visits, respectively, with a decline mainly due to censoring at close-out. Approximately 25% of women failed to return bottles, whose tablet intakes were modestly lower than those of bottle-returnees. Notwithstanding, 75 to 84% in both groups recalled missing <2 d and <5.3% missing >30 d. Interval-specific regression slopes (β₁) were 0.88–0.78 [95% confidence intervals (CIs) within +0.06 for first 5 intervals], reflecting a ∼20% over-reporting by recall, with r = 0.77–0.58, and root mean square errors (RMSE) of 10–12 tablets, reflecting model error in prediction, normalized to 7%–10% of interval ranges. Cumulative models yielded β₁ = 0.83–0.77 with similarly narrow 95% CIs, r = 0.79–0.64, and RMSE = 12–24 tablets, normalized to 7%–13% of range.

Conclusions

Histories of recalled tablet days missed provide a reliable and reasonably valid estimate of tablet disappearance from MMS bottles. Further research is warranted to correct a consistently reported ∼20% average overestimate of tablet intake.

背景：多种微量营养素补充（MMS）是低收入国家出现的产前保健新标准。评估依从性是一个关键的实施结果，需要验证。目的：根据在约旦为巴勒斯坦难民服务的近东救济工程处诊所在随访期间错过的召回药片天数，验证产前每日MMS的依从性。方法本研究是在产前MMS与标准护理铁叶酸补充的实施试验中进行的。在13个诊所登记时，孕妇每天接受180支重111克的MMS（瓶中干燥剂= 26克，片剂= 0.47克）。在七次随访中，退回的药瓶在数字秤上称重到最近的克，并记录召回的药片天数。从瓶中取出的片剂，根据瓶重减少量估计，对服用的片剂进行回归，通过从间隔长度中减去遗漏的片剂天数得到。对自登记以来的累积间隔进行了类似的分析。结果9754名登记妇女中，完成1 - 7次随访的分别为7608人（78%）、6208人（63.6%）、4833人（49.5%）、3409人（34.9%）、2159人（22.1%）、1063人（10.9%）、384人（3.9%），主要原因是闭关审查。大约25%的女性没有归还瓶子，她们的药片摄入量略低于归还瓶子的女性。尽管如此，两组中75%至84%的患者回忆缺失了2天，5.3%的患者回忆缺失了30天。区间特异性回归斜率（β1）为0.88-0.78[前5个区间的95%置信区间（ci）在+0.06范围内]，反映了召回率多报了约20%，r = 0.77-0.58，均方根误差（RMSE）为10-12片，反映了预测中的模型误差，归一化为区间范围的7%-10%。累积模型得到β1 = 0.83-0.77, 95% ci同样窄，r = 0.79-0.64, RMSE = 12-24片，归一化范围为7%-13%。结论遗漏召回天数的历史为MMS瓶中药片的消失提供了可靠、合理、有效的估计。有必要进一步的研究来纠正一贯报道的片剂摄入量平均高估约20%。

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引用次数: 0

Associations Between Healthy and Plant-Based Dietary Patterns and Cognitive Reserve: A Cross-Sectional Analysis of the 1946 British Birth Cohort 健康和植物性饮食模式与认知储备之间的关系：1946年英国出生队列的横断面分析

IF 3.2 Q2 NUTRITION & DIETETICS

Current Developments in Nutrition

Pub Date : 2025-12-01 DOI: 10.1016/j.cdnut.2025.107599

Kelly C Cara , Tammy M Scott , Paul F Jacques , Mei Chung

Background

Cognitive reserve (CR) is the ability to compensate for brain changes, injury, and disease, and it is measured by acquired knowledge and experiences. Genes and environmental factors influence CR, but the role of diet is unclear.

Objectives

This study examined associations between CR and alignment with different dietary patterns and investigated diet’s unique contribution to variability in CR.

Methods

We applied cross-sectional methods to data from the National Survey of Health and Development’s 1946 British Birth Cohort. National Adult Reading Test (NART) scores at age 53 identified CR levels. Scores for the Healthy Eating Index (HEI)-2020 and Plant-Based Diet Indexes (PDIs overall, healthful [hPDI], and unhealthful [uPDI]) were calculated from diet recalls and diaries at ages 4, 36, 43, and 53. Multiple linear regression models identified associations between NART and cumulative mean dietary index scores while adjusting for key confounders. Owen value R² decomposition determined variance explained by covariate groups.

Results

Participants with complete data were analyzed (n = 2514, 48% male). In regression models, NART was positively associated with HEI, PDI, and hPDI but inversely associated with uPDI. Compared with the lowest quintile, those in the highest quintile for HEI, PDI, and hPDI had significantly higher NART [adjusted mean difference (95% CI) for HEI: 2.25 (1.19, 3.30); PDI: 1.17 (0.19, 2.15); hPDI: 1.42 (0.51, 2.33)], whereas the highest quintile for uPDI showed lower NART (−1.55 [−2.55, −0.54]). Associations weakened but remained significant in models additionally adjusted for childhood cognitive ability. Among dietary patterns, HEI explained the most variation in NART (HEI 2.84%, uPDI 1.51%, hPDI 1.05%, PDI 0.51%).

Conclusions

CR was positively associated with healthy dietary patterns and inversely associated with unhealthful plant-based dietary patterns. Diet uniquely explained variations in CR and should be considered among influential lifestyle factors in future research. Longitudinal analyses are needed to confirm these findings.

认知储备（cognitive reserve， CR）是补偿大脑变化、损伤和疾病的能力，它是通过获得的知识和经验来衡量的。基因和环境因素影响CR，但饮食的作用尚不清楚。目的本研究考察了CR与不同饮食模式的一致性之间的关系，并调查了饮食对CR变异性的独特贡献。方法我们采用横断面方法对1946年英国国家健康与发展调查的出生队列数据进行了分析。全国成人阅读测试（NART）分数在53岁确定CR水平。健康饮食指数(HEI)-2020和植物性饮食指数（PDIs总体，健康[hPDI]和不健康[uPDI]）的得分是根据4岁、36岁、43岁和53岁的饮食回忆和日记计算的。在调整关键混杂因素后，多元线性回归模型确定了NART与累积平均饮食指数评分之间的关联。欧文值R2分解确定方差由协变量组解释。结果纳入资料完整的2514例，其中男性48%。在回归模型中，NART与HEI、PDI和hPDI呈正相关，而与uPDI呈负相关。与最低五分位数相比，HEI、PDI和hPDI最高五分位数的患者NART明显更高[HEI的调整平均差异（95% CI）： 2.25 (1.19, 3.30)；Pdi: 1.17 (0.19, 2.15)；hPDI: 1.42(0.51, 2.33)]，而uPDI最高的五分位数显示较低的NART（- 1.55[- 2.55, - 0.54]）。关联减弱，但在额外调整儿童认知能力的模型中仍然显著。在膳食模式中，HEI对NART的解释最多（HEI为2.84%，uPDI为1.51%，hPDI为1.05%，PDI为0.51%）。结论scr与健康饮食模式呈正相关，与不健康植物性饮食模式负相关。饮食独特地解释了CR的变化，在未来的研究中应将其视为影响生活方式的因素之一。需要进行纵向分析来证实这些发现。

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引用次数: 0

Diet and Lifestyle Quality in Australian Females with Endometrial Cancer at Diagnosis: Insights from the Fertility-sparing Management for Early Endometrial Cancer (FeMMe) Trial 澳大利亚子宫内膜癌女性诊断时的饮食和生活方式质量：来自早期子宫内膜癌（FeMMe）试验保留生育能力管理的见解

IF 3.2 Q2 NUTRITION & DIETETICS

Current Developments in Nutrition

Pub Date : 2025-12-01 DOI: 10.1016/j.cdnut.2025.107572

Ruqaiya Al Ramadhani , Monika Janda , Mary Playdon , Andreas Obermair

Background

Diet, lifestyle, and body composition may impact quality of life (QoL) and health outcomes in females with endometrial cancer (EC). Many seek guidance on improving prognosis, treatment outcomes, and QoL through nutrition and other modifiable lifestyle factors.

Objectives

This study aims to investigate diet and lifestyle quality in FeMMe trial participants and associations with glycemic control, body composition, QoL, and mental health before treatment.

Methods

Baseline data from the multicenter, 3-arm, phase II FeMMe trial (NCT01686126), which enrolled females with obesity and early-stage EC or complex endometrial hyperplasia with atypia undergoing conservative hormonal therapy. The Mediterranean diet score (MDS), World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR), and Extended Healthy Lifestyle Index (EHLI) scores were derived from self-reported dietary and lifestyle data. QoL, depression, and anxiety were measured using validated tools. Anthropometry and body composition (height, weight, hip, and waist circumference) were measured by a study nurse. Glycemic control was assessed using blood samples, utilizing the Homeostatic Model Assessment for Insulin Resistance as the measurement metric. Bonferroni correction applied for multiple comparisons; nominal associations defined as P < 0.05 but ≥ 0.001.

Results

Approximately 40.7%, 31.3%, and 34.7% of females had good diet and/or lifestyle quality according to the MDS, WCRF/AICR, and EHLI, respectively. We found that higher WCRF/AICR scores, expressed per standard deviation (SD) increase, were nominally associated with a better overall QoL score (β_perSD = 4.45, 95% confidence interval (CI): 0.30, 8.61, P = 0.036), and with higher anxiety and depression scores (β_perSD = 0.60, 95% CI: 0.09, 1.11, P = 0.02). For the EHLI, each SD increase was nominally associated with 8% reduction in insulin resistance (Exp(β_perSD) = 0.92, 95% CI: 0.85, 0.996, P = 0.039).

Conclusions

Among females with EC and BMI ≥ 30 kg/m², healthier lifestyle patterns were associated with better QoL and insulin sensitivity, but also higher anxiety and depression.

饮食、生活方式和身体组成可能影响子宫内膜癌（EC）女性患者的生活质量（QoL）和健康结果。许多人寻求通过营养和其他可改变的生活方式因素来改善预后、治疗结果和生活质量的指导。目的本研究旨在探讨FeMMe试验参与者的饮食和生活方式质量及其与治疗前血糖控制、身体成分、生活质量和心理健康的关系。方法基线数据来自多中心，3组，II期FeMMe试验（NCT01686126），该试验纳入了接受保守激素治疗的肥胖和早期EC或复杂子宫内膜增生伴异型的女性。地中海饮食评分（MDS）、世界癌症研究基金会/美国癌症研究所（WCRF/AICR）和扩展健康生活方式指数（EHLI）评分来源于自我报告的饮食和生活方式数据。使用经过验证的工具测量生活质量、抑郁和焦虑。由一名研究护士测量人体测量和身体组成（身高、体重、臀围和腰围）。使用血液样本评估血糖控制，使用胰岛素抵抗稳态模型评估作为测量指标。多次比较采用Bonferroni校正；名义关联定义为P <； 0.05但≥0.001。结果根据MDS、WCRF/AICR和EHLI，约有40.7%、31.3%和34.7%的女性饮食和/或生活方式质量良好。我们发现，较高的WCRF/AICR评分，以每标准差（SD）的增加表示，名义上与较好的总体生活质量评分（βperSD = 4.45, 95%可信区间（CI）： 0.30, 8.61, P = 0.036）以及较高的焦虑和抑郁评分（βperSD = 0.60, 95% CI: 0.09, 1.11, P = 0.02）相关。对于EHLI，每增加一个SD，名义上与胰岛素抵抗降低8%相关（Exp(βperSD) = 0.92, 95% CI: 0.85, 0.996, P = 0.039）。结论在EC和BMI≥30 kg/m2的女性中，健康的生活方式与更好的生活质量和胰岛素敏感性相关，但也与更高的焦虑和抑郁相关。

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引用次数: 0

Equivalent Glycemic Load and Insulinemic Responses Elicited by Low-Carbohydrate Foods: A Randomized Trial in Healthy Adults 低碳水化合物食物引起的等效血糖负荷和胰岛素反应：一项健康成年人的随机试验

IF 3.2 Q2 NUTRITION & DIETETICS

Current Developments in Nutrition

Pub Date : 2025-12-01 DOI: 10.1016/j.cdnut.2025.107594

Thomas MS Wolever , Kevin Miller , Taylor Banh

Background

The information on the Nutrition Facts Label may overestimate the available-carbohydrate (avCHO) content and glycemic impact of some low-carbohydrate foods containing novel carbohydrates.

Objectives

The primary objective was to test the hypothesis that the glycemic impact of low-carbohydrate foods, quantified as equivalent-glycemic-load (EGL), measures their avCHO content accurately and precisely (within ±1g). The secondary objectives were to measure the glycemic and insulinemic responses elicited by 7 low-carbohydrate foods.

Methods

Healthy overnight-fasted adults (n = 25) consumed 20.8 g or 5.2 g avCHO from white bread (WB20.8, WB5.2, respectively), or 1 of 7 test-products in random order; each subject tested WB20.8 twice. Plasma-glucose responses were measured in all subjects with serum-insulin measured in 10. For each subject, 20.8 × T/W was calculated [T = incremental area under the glucose curve (iAUC) after the test-food, W = mean iAUC after WB20.8]; the mean of the resulting values (excluding outliers) was the test-food EGL.

Results

The expected EGL of WB5.2 was 5.2 g and the measured value was 4.0 g (95% margin of error = 0.6 g). On the basis of the food-label, the test-products contained 3–12 g avCHO (total-carbohydrate minus dietary-fiber). However, because 5 of the test-products contained allulose, which is not included in dietary-fiber and not quantified on the food-label, their content of netCHO (avCHO minus allulose) ranged from 3 to 6 g; even so, their EGL values varied from just 0.6 to 2.4 g. The mean insulin responses elicited by the test-products were positively related to their protein content, but none differed significantly from that elicited by WB5.2.

Conclusions

The results support the hypothesis that the EGL measure is accurate and precise to within ∼±1 g. The EGLs of the 7 test-products were 20%–90% less than expected from their food-labels. The test-products elicited small insulin responses that were positively related to their protein content.

This trial was registered at clinicaltrials.gov as NCT05870891 (https://clinicaltrials.gov/study/NCT05870891).

背景：营养成分标签上的信息可能高估了一些含有新型碳水化合物的低碳水化合物食物的有效碳水化合物（avCHO）含量和对血糖的影响。主要目的是验证低碳水化合物食物的血糖影响，量化为等效血糖负荷（EGL），准确和精确地测量其avCHO含量（±1g）。次要目的是测量7种低碳水化合物食物引起的血糖和胰岛素反应。方法健康禁食的成年人（n = 25）从白面包（分别为WB20.8和WB5.2）或随机从7种试验产品中选择1种食用20.8 g或5.2 g的cho；每位受试者测试WB20.8两次。测定所有受试者的血糖反应，并测定血清胰岛素。每个受试者计算20.8 × T/W [T =试验食物后葡萄糖曲线下增量面积（iAUC）， W = WB20.8后平均iAUC]；结果值的平均值（不包括异常值）为测试食品EGL。结果WB5.2的预期EGL为5.2 g，实测值为4.0 g（95%误差范围为0.6 g）。根据食品标签，测试产品含有3 - 12g的avCHO（总碳水化合物减去膳食纤维）。然而，由于5个测试产品含有不包含在膳食纤维中且未在食品标签上量化的allulose，因此它们的netCHO （avCHO减去allulose）含量在3至6 g之间；即便如此，他们的EGL值从0.6 g到2.4 g不等。试验产品引起的平均胰岛素反应与其蛋白质含量呈正相关，但与WB5.2引起的胰岛素反应无显著差异。结论EGL测量结果准确，精确到~±1g。7种测试产品的egl比食品标签上的预期值低20%-90%。测试产品引起了与蛋白质含量呈正相关的小胰岛素反应。该试验在clinicaltrials.gov注册为NCT05870891 （https://clinicaltrials.gov/study/NCT05870891）。

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引用次数: 0

Trends in Unprocessed Red and Processed Meat Consumption in the Mexican Population, 2006–2020 2006-2020年墨西哥人口未加工红肉和加工肉消费趋势

IF 3.2 Q2 NUTRITION & DIETETICS

Current Developments in Nutrition

Pub Date : 2025-12-01 DOI: 10.1016/j.cdnut.2025.107598

Kaela Connors , Lindsay M Jaacks , Peter Alexander , Juan A Rivera , Carolina Batis

Background

Meat consumption trends in Mexico are poorly understood, and this may have implications for Mexico’s diet-related disease burden and the sustainability of diets.

Objectives

We assessed trends in protein-rich food groups and the contribution of unprocessed red and processed meat to nutrient intake.

Methods

We used nationally representative (all ages) dietary information from the Mexican National Health and Nutrition Survey, collected using a semiquantitative food frequency questionnaire in 2006, 2012, 2016, 2018, and 2020. We tested for time trends and sociodemographic differences in daily consumption using survey-weighted generalized linear regression, adjusting for total energy intake. The contribution to nutrient intake was assessed from a 2016 24-h dietary recall.

Results

Energy-adjusted unprocessed red meat consumption decreased slightly from 2006 to 2020, but processed meat remained unchanged [change in daily consumption (g) per survey cycle (95% confidence interval) β = −0.28 (−0.49, −0.08) and 0.01 (−0.06, 0.09), respectively]. Among 6–19 y olds, unprocessed red and processed meat consumption marginally increased. Other protein-rich foods such as seafood, legumes, nuts, and seeds decreased over time, whereas poultry and dairy increased. Egg consumption remained constant. Unprocessed red and processed meat contributed substantially to per capita heme iron intake (23% and 26%, respectively) and vitamin B12 intake (17% and 9.8%, respectively).

Conclusions

Processed meat consumption is well-above dietary targets and has not declined in Mexico, with modest increases among young people, posing potentially negative health and environmental consequences. Meat was a major contributor to heme iron and vitamin B12, but less so (<10%) for other essential nutrients. Therefore, policies to encourage meat reduction, particularly processed meat, are unlikely to adversely affect nutritional status.

墨西哥的肉类消费趋势尚不清楚，这可能对墨西哥与饮食有关的疾病负担和饮食的可持续性产生影响。目的：我们评估了蛋白质丰富食物组的趋势，以及未加工的红肉和加工过的肉对营养摄入的贡献。方法采用半定量食物频率问卷收集的2006年、2012年、2016年、2018年和2020年墨西哥国家健康与营养调查中具有全国代表性（所有年龄段）的饮食信息。我们使用调查加权广义线性回归测试了每日消费的时间趋势和社会人口差异，并对总能量摄入进行了调整。对营养摄入的贡献是通过2016年24小时饮食召回来评估的。结果2006 - 2020年，经能量调整后的未加工红肉消费量略有下降，但加工肉消费量保持不变[每个调查周期的日消费量(g)变化（95%置信区间）β分别= - 0.28（- 0.49,- 0.08）和0.01(- 0.06,0.09)]。在6-19岁的青少年中，未加工的红肉和加工肉类的消费量略有增加。其他富含蛋白质的食物，如海鲜、豆类、坚果和种子，随着时间的推移会减少，而家禽和乳制品则会增加。鸡蛋消费量保持不变。未加工的红肉和加工肉对人均血红素铁摄入量（分别为23%和26%）和维生素B12摄入量（分别为17%和9.8%）贡献很大。墨西哥的加工肉类消费量远高于饮食目标，而且没有下降，年轻人的消费量略有增加，这可能对健康和环境造成负面影响。肉类是血红素铁和维生素B12的主要来源，但对其他必需营养素的贡献较少（10%）。因此，鼓励减少肉类，特别是加工肉类的政策不太可能对营养状况产生不利影响。

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引用次数: 0

The Effects of Acute Caffeine Supplementation in Combination with Postactivation Performance Enhancement on Performance and Fatigue in High-Level Male Volleyball Athletes 急性咖啡因补充联合激活后性能增强对高水平男子排球运动员性能和疲劳的影响

IF 3.2 Q2 NUTRITION & DIETETICS

Current Developments in Nutrition

Pub Date : 2025-12-01 DOI: 10.1016/j.cdnut.2025.107601

Marjan Shidai , Hamid Rajabi , Neda Khaledi , Aref Basereh , Somayeh Ahmadabadi

Background

While both post-activation performance enhancement (PAPE) and caffeine (CAF) independently enhance performance, their combined effects on physical performance and the levels of central and peripheral fatigue remain unexplored.

Objectives

This study assessed the impact of the PAPE method and CAF supplementation on central and peripheral fatigue following a fatigue-inducing protocol in elite male volleyball athletes.

Methods

The study employed a convenience sampling method to recruit 40 voluntary participants (18–30 y), who were then divided into 4 groups: PAPE group (N = 10), CAF group (N = 10), PAPE + CAF group (CAF + PAPE, N = 10), and control group (CG, N = 10). The CAF group received a CAF supplement of 6 mg/kg of body mass 20 min before the warming up for 10 min, whereas the PAPE group performed 2 sets of back squats at 80% of 1RM (4 reps/set) 2 min before the protocol.

Results

Between-group comparisons revealed that the PAPE + CAF group demonstrated a significant improvement in the performance variables, including time to exhaustion, number of rounds, and serum dopamine concentrations, compared with all other groups (P < 0.05), whereas serum ammonia, serotonin, and prolactin concentrations decreased significantly compared with all other groups (P < 0.05). The CAF group also showed higher values in these performance and biochemical measures than the CG and PAPE groups, but these were lower than those in the CAF + PAPE group (P < 0.05). No significant differences were found for rating of perceived exertion or uric acid (P > 0.05).

Conclusions

This study confirms CAF's primary role in enhancing performance and reducing fatigue. The combined CAF + PAPE intervention provided a distinct advantage only for the number of rounds completed, but showed no significant benefit over CAF alone for time to exhaustion or most biochemical markers.

虽然激活后性能增强（PAPE）和咖啡因（CAF）都能单独提高性能，但它们对身体性能和中枢和外周疲劳水平的综合影响仍未被研究。目的：本研究评估PAPE方法和CAF补充对优秀男排运动员疲劳诱导方案后中枢和外周疲劳的影响。方法采用方便抽样法，随机招募年龄在18-30岁的志愿者40名，将其分为4组：PAPE组（N = 10）、CAF组（N = 10）、PAPE + CAF组（CAF + PAPE, N = 10）和对照组（CG, N = 10）。CAF组在热身前20分钟补充6 mg/kg体重的CAF，持续10分钟，而PAPE组在热身前2分钟以80%的1RM（4次/组）进行2组背部深蹲。结果组间比较显示，与其他组相比，PAPE + CAF组在疲劳时间、回合数和血清多巴胺浓度等性能变量上均有显著改善（P < 0.05），而血清氨、血清素和催乳素浓度较其他组显著降低（P < 0.05）。CAF组在这些性能指标和生化指标上均高于CG和PAPE组，但低于CAF + PAPE组（P < 0.05）。两组的劳累程度和尿酸评分无显著差异（P > 0.05）。结论：本研究证实了CAF在提高运动成绩和减轻疲劳方面的主要作用。CAF + PAPE联合干预仅在完成的回合数上有明显的优势，但在衰竭时间或大多数生化指标上，与CAF单独干预相比没有明显的优势。

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引用次数: 0

Effects of Maternal Feeding Style and Child Eating Behaviors on Body Mass Index in Young Children in the Hispanic Community Health Study/Study of Latinos Family Lifestyle Outcomes Research Study 西班牙裔社区健康研究/拉丁裔家庭生活方式结局研究中母亲喂养方式和儿童饮食行为对幼儿体重指数的影响

IF 3.2 Q2 NUTRITION & DIETETICS

Current Developments in Nutrition

Pub Date : 2025-11-29 DOI: 10.1016/j.cdnut.2025.107611

Sarah Gonzalez-Nahm , Daniela Sotres-Alvarez , Carmen R Isasi , Linda C Gallo , Christina Cordero , Alan M Delamater , Martha L Daviglus , Linda Van Horn , Anna Maria Siega-Riz

Background

Children’s eating behaviors influence weight, but the relationships among children’s eating behaviors, caregiver feeding styles, and modifying maternal and child factors remain unclear.

Objectives

This study aimed to examine the associations between 1) child eating behaviors and body mass index (BMI) z-scores, and 2) caregiver feeding style and child eating behaviors.

Methods

Data from 290 Hispanic mother–child dyads (children aged 3–9 y) in the Hispanic Community Health Study/Study of Latinos Family Lifestyle Outcomes Research cohort were analyzed cross-sectionally. Child eating behaviors, caregiver feeding styles, and child BMI z-scores were assessed. Linear regression examined: 1) child eating behaviors and BMI z-scores, and 2) caregiver feeding styles and child eating behaviors. Models adjusted for maternal marital status, prepregnancy BMI, child health, Supplemental Nutrition Assistance Program status, poverty level, and study site.

Results

Higher child food responsiveness [β = 0.16; 95% confidence interval (CI): 0.01, 0.32] and enjoyment of food (β = 0.18; 95% CI: 0.02, 0.33) were associated with higher BMI z-scores, while greater satiety responsiveness (β = −0.23; 95% CI: −0.42, −0.04) was associated with lower BMI z-score. Authoritarian feeding style was associated with a lower enjoyment of food (β = −0.72; 95% CI: −1.06, −0.38), greater food fussiness (β = 0.42; 95% CI: 0.09, 0.76), greater satiety responsiveness (β = 0.57; 95% CI: 0.31, 0.84), and greater slowness in eating (β = 0.44; 95% CI: 0.13, 0.76). An indulgent feeding style was associated with a lower desire to drink (β = −0.52; 95% CI: −0.90, −0.13), lower satiety responsiveness (β = −0.36; 95% CI: −0.65, −0.10), and lower emotional undereating (β = −0.55, 95% CI: −0.84, −0.25). An uninvolved feeding style was associated with lower emotional undereating (β = −0.63; 95% CI: −0.97, −0.29).

Conclusions

Child food approach behaviors correlate with higher BMI. Findings on caregiver feeding styles and child eating behaviors show complex, sometimes unexpected patterns, highlighting the need for further interdisciplinary research.

儿童的饮食行为影响体重，但儿童的饮食行为、照顾者的喂养方式和改变母婴因素之间的关系尚不清楚。目的探讨儿童饮食行为与身体质量指数（BMI） z分数的关系，以及照料者喂养方式与儿童饮食行为的关系。方法对来自拉美裔社区健康研究/拉美裔家庭生活方式结局研究队列的290名拉美裔母子对（3-9岁儿童）的数据进行横断面分析。评估儿童饮食行为、照顾者喂养方式和儿童BMI z分数。线性回归检验：1)儿童饮食行为与BMI z-score； 2)照顾者喂养方式与儿童饮食行为。模型根据产妇婚姻状况、孕前BMI、儿童健康、补充营养援助计划状态、贫困水平和研究地点进行了调整。结果儿童食物反应性增高[β = 0.16；95%可信区间（CI）： 0.01, 0.32]和食物享受（β = 0.18; 95% CI: 0.02, 0.33）与较高的BMI z-score相关，而较高的饱腹反应（β = - 0.23; 95% CI: - 0.42, - 0.04）与较低的BMI z-score相关。权威喂养方式与较低的食物享受（β = - 0.72; 95% CI: - 1.06, - 0.38），更大的食物挑剔（β = 0.42; 95% CI: 0.09, 0.76），更大的饱腹反应（β = 0.57; 95% CI: 0.31, 0.84）和更慢的进食（β = 0.44; 95% CI: 0.13, 0.76）相关。放纵的喂养方式与较低的饮酒欲望（β = - 0.52; 95% CI: - 0.90, - 0.13），较低的饱腹感反应（β = - 0.36; 95% CI: - 0.65, - 0.10）和较低的情绪不足（β = - 0.55, 95% CI: - 0.84, - 0.25）相关。无参与式喂养方式与较低的情绪不足相关（β = - 0.63; 95% CI: - 0.97, - 0.29）。结论儿童食物接近行为与高BMI相关。关于照顾者喂养方式和儿童饮食行为的研究结果显示出复杂的，有时是意想不到的模式，强调了进一步跨学科研究的必要性。

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引用次数: 0

Relationship between Fish Consumption and Undernutrition among Young Indian Children 印度儿童食用鱼类与营养不良的关系

IF 3.2 Q2 NUTRITION & DIETETICS

Current Developments in Nutrition

Pub Date : 2025-11-29 DOI: 10.1016/j.cdnut.2025.107610

Rajesh Kumar Rai , Sabri Bromage , Baban Bayan , Baishnaba Charan Ratha , Rockli Kim , Sourabh Kumar Dubey , Wanjiku N Gichohi-Wainaina , Edward H Allison , Cristiano M Rossignoli , Arun Panemangalore Padiyar , S.V. Subramanian , Christopher D Golden

Background

Although aquatic foods, particularly fish, hold promise as a dietary intervention to address child undernutrition, evidence supporting their role in Indian context remains limited and mixed, thus inconclusive.

Objectives

We assessed the association between fish consumption and undernutrition among children aged 6–23 mo using data from India's nationally representative, cross-sectional 2019–2021 National Family Health Survey (NFHS-5). This survey covered 707 districts across 36 states/union territories.

Methods

Undernutrition indicators included stunting (sample: 59,560), wasting (sample: 59,145), underweight (sample: 61,450), any anthropometric failure (sample: 60,440), and anemia (sample: 58,850). Stunting, wasting, and underweight were defined as <–2 standard deviations from the median of z-scores for height-for-age, weight-for-height, and weight-for-age of the reference population, respectively. Children measured as being either stunted, wasted, or underweight were defined as having any anthropometric failure. Children were classified as having any anemia, based on hemoglobin levels of <10.5 g/dL. Children's 24-h dietary recall provided information on fish consumption. We used modified Poisson regression models with robust error variance to attain the study objective.

Results

Nationally, a strikingly low prevalence of fish consumption among young children was recorded, with only 4.5% of them reporting intake in the preceding 24 h. Children in 111 of the 707 districts surveyed in NFHS-5 reported no fish consumption. Regression analysis revealed no association (P > 0.1) between fish consumption and anthropometric indicators (stunting, wasting, underweight, and any anthropometric failure) among children aged 6–23 mo. However, a protective association of fish consumption with anemia was observed (relative risk: 0.947; 95% confidence interval: 0.921, 0.973; P < 0.001).

Conclusion

Encouraging fish consumption through public initiatives like the National Nutrition Mission could be a valuable strategy for mitigating the burden of anemia among young children. Further research utilizing detailed food consumption data, including fish intake, is warranted to investigate its impact on child health.

尽管水生食物，特别是鱼类，有望作为解决儿童营养不良的饮食干预措施，但支持其在印度背景下的作用的证据仍然有限且混杂，因此尚无定论。我们利用印度2019-2021年全国家庭健康调查（NFHS-5）的全国代表性横断面数据，评估了6-23个月儿童食用鱼类与营养不良之间的关系。这项调查覆盖了36个邦/联邦属地的707个地区。方法营养不良指标包括发育迟缓（样本：59,560）、消瘦（样本：59,145）、体重不足（样本：61,450）、任何人体测量失败（样本：60,440）和贫血（样本：58,850）。发育迟缓、消瘦和体重不足的定义分别为参照人群身高年龄比、身高体重年龄比和体重年龄比z分数中位数的<； 2个标准差。被测量为发育不良、消瘦或体重过轻的儿童被定义为有任何人体测量失败。根据血红蛋白水平10.5 g/dL，儿童被归类为贫血。儿童24小时饮食召回提供了有关鱼类消费的信息。我们使用修正的泊松回归模型和稳健的误差方差来达到研究目标。结果在全国范围内，记录的幼儿食用鱼类的流行率非常低，只有4.5%的儿童报告在过去24小时内摄入了鱼类。在NFHS-5调查的707个地区中，有111个地区的儿童报告没有食用鱼类。回归分析显示，在6-23月龄儿童中，鱼类消费与人体测量指标（发育迟缓、消瘦、体重不足和任何人体测量失败）之间没有关联（P > 0.1）。然而，观察到鱼类消费与贫血之间存在保护性关联（相对风险：0.947；95%可信区间：0.921,0.973;P < 0.001）。结论通过国家营养使命等公共倡议鼓励鱼类消费可能是减轻幼儿贫血负担的宝贵策略。有必要利用详细的食物消费数据（包括鱼类摄入量）进行进一步研究，以调查其对儿童健康的影响。

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引用次数: 0

The UK Food Environment: A Systematic Review of Domains, Methodologies, and Outcomes 英国食品环境：领域，方法和结果的系统回顾

IF 3.2 Q2 NUTRITION & DIETETICS

Current Developments in Nutrition

Pub Date : 2025-11-01 DOI: 10.1016/j.cdnut.2025.107573

Deksha Kapoor , Kirsteen Shields , Christian Reynolds , Martín Del Valle Menendez , Lindsay M Jaacks

Understanding food environments is crucial for developing policies and interventions to enhance the healthfulness and sustainability of UK diets. We systematically reviewed published scientific research to answer 2 research questions. First, what types and domains of the food environment have been assessed in the United Kingdom using what methodologies? Domains included availability, affordability, promotion, product characteristics/quality, convenience, and sustainability. Second, what outcomes have been assessed in relation to food environments? Outcomes were classified as descriptive (describing the food environment), dietary intake, and health. Articles published between January 2000 and December 2024 were identified by searching 7 databases: CAB Abstracts, CINAHL, EMBASE, Global Health, PubMed, Scopus, and Web of Science. A total of 31,457 articles were identified, 3418 full texts were reviewed, and 286 articles were included. Another 26 articles were included after screening the references of articles identified in the database search. Thus, data were extracted from a total of 312 articles. The most common domain studied was availability (n = 100, 32%), followed by product characteristics/quality (n = 94, 30%) and promotion (n = 33, 10%). There was a paucity of research on the domains of sustainability (n = 19, 6%) and affordability (n = 16, 5%), with no articles on the domain of convenience. Only 49 articles (16%) evaluated >1 domain. Most articles were descriptive (n = 206, 66%); 64 (20%) evaluated the association of the food environment with dietary intake and 42 (13%) evaluated the association with health, nearly all with obesity. The current literature on the food environment in the United Kingdom focuses largely on availability in the food retail space. More research is needed to understand how different domains of the food environment interact to influence dietary intake and health.

The protocol was registered at PROSPERO as CRD42022306066 on 8 February 2022.

了解食物环境对于制定政策和干预措施以提高英国饮食的健康和可持续性至关重要。我们系统地回顾了已发表的科学研究，以回答两个研究问题。首先，在英国，用什么方法评估了食品环境的哪些类型和领域？领域包括可用性、可负担性、促销、产品特性/质量、便利性和可持续性。第二，与食品环境相关的评估结果是什么？结果分为描述性（描述食物环境）、饮食摄入和健康。2000年1月至2024年12月间发表的文章通过检索7个数据库进行鉴定：CAB Abstracts、CINAHL、EMBASE、Global Health、PubMed、Scopus和Web of Science。共识别31457篇文献，审阅全文3418篇，纳入286篇文献。在筛选数据库检索中找到的文章的参考文献后，又纳入了26篇文章。因此，数据是从312篇文章中提取的。最常见的研究领域是可用性（n = 100, 32%），其次是产品特性/质量（n = 94, 30%）和促销（n = 33, 10%）。关于可持续性（n = 19.6%）和可负担性（n = 16.5%）领域的研究很少，而关于便利性领域的研究则没有。只有49篇文章（16%）评估了1个领域。大多数文章是描述性的（n = 206, 66%）；64家（20%）评估了食物环境与饮食摄入的关系，42家（13%）评估了食物环境与健康的关系，几乎都与肥胖有关。目前关于英国食品环境的文献主要集中在食品零售空间的可用性上。需要更多的研究来了解食物环境的不同领域如何相互作用来影响饮食摄入和健康。该协议于2022年2月8日在普洛斯彼罗注册为CRD42022306066。

{"title":"The UK Food Environment: A Systematic Review of Domains, Methodologies, and Outcomes","authors":"Deksha Kapoor , Kirsteen Shields , Christian Reynolds , Martín Del Valle Menendez , Lindsay M Jaacks","doi":"10.1016/j.cdnut.2025.107573","DOIUrl":"10.1016/j.cdnut.2025.107573","url":null,"abstract":"<div><div>Understanding food environments is crucial for developing policies and interventions to enhance the healthfulness and sustainability of UK diets. We systematically reviewed published scientific research to answer 2 research questions. First, what types and domains of the food environment have been assessed in the United Kingdom using what methodologies? Domains included availability, affordability, promotion, product characteristics/quality, convenience, and sustainability. Second, what outcomes have been assessed in relation to food environments? Outcomes were classified as descriptive (describing the food environment), dietary intake, and health. Articles published between January 2000 and December 2024 were identified by searching 7 databases: CAB Abstracts, CINAHL, EMBASE, Global Health, PubMed, Scopus, and Web of Science. A total of 31,457 articles were identified, 3418 full texts were reviewed, and 286 articles were included. Another 26 articles were included after screening the references of articles identified in the database search. Thus, data were extracted from a total of 312 articles. The most common domain studied was availability (<em>n =</em> 100, 32%), followed by product characteristics/quality (<em>n =</em> 94, 30%) and promotion (<em>n =</em> 33, 10%). There was a paucity of research on the domains of sustainability (<em>n =</em> 19, 6%) and affordability (<em>n =</em> 16, 5%), with no articles on the domain of convenience. Only 49 articles (16%) evaluated >1 domain. Most articles were descriptive (<em>n =</em> 206, 66%); 64 (20%) evaluated the association of the food environment with dietary intake and 42 (13%) evaluated the association with health, nearly all with obesity. The current literature on the food environment in the United Kingdom focuses largely on availability in the food retail space. More research is needed to understand how different domains of the food environment interact to influence dietary intake and health.</div><div>The protocol was registered at PROSPERO as CRD42022306066 on 8 February 2022.</div></div>","PeriodicalId":10756,"journal":{"name":"Current Developments in Nutrition","volume":"9 11","pages":"Article 107573"},"PeriodicalIF":3.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145464198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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