International Journal of Ayurvedic Medicine最新文献

{"title":"Traditional Indian Medicine Improves Clinical Outcome in Non-alcoholic fatty Liver diseases - A Systematic Review and Meta-analysis","authors":"Piyush Chaudhary, B. Rathi, N. Lamba, A. Sharma, Renu Rathi","doi":"10.47552/ijam.v14i2.3395","DOIUrl":"https://doi.org/10.47552/ijam.v14i2.3395","url":null,"abstract":"Background: Non- Alcoholic Fatty Liver Disease (NAFLD) is a rapidly emerging liver disease linked strongly to metabolic syndrome. In the absence of specific pharmacological agents for the effective treatment of NAFLD, current treatment mainly focuses on lifestyle and dietary modifications. Several agents referenced in Ayurvedic texts have shown promising effects in patients over centuries of use. But the outcomes reported by various randomized clinical trials (RCTs) for the efficacy of herbs in non-alcoholic fatty liver disease (NAFLD) are conflicting. Objective: This study aims to systematically review and conduct meta-analysis of the available evidence to evaluate the efficacy and safety of Ayurveda-referenced drugs.  Methodology: The electronic databases PubMed, Web of Science, Embase, Cochrane library, and ARP were searched up to May 2022 to identify relevant studies. Quality of studies was evaluated using modified Jadad Scale. Risk of bias was assessed using Cochrane risk of bias tool. Result: The search retrieved 1352 studies, but only 18 studies were finally evaluated. Statistical analysis showed significant reduction in grades of fatty liver (RR: 2.42, 95% CI; 1.52, 3.86), AST (SMD: -0.91, 95% CI; -1.04, 0.08;) and ALT (SMD = − 0.91; 95% CI; − 1.53, − 0.28; P < 0.00001). Conclusion: Ayurveda drugs have shown positive results in managing NAFLD, as evidenced by the limited available data. More quality-based RCT’s using standardized Ayurveda drugs with large sample sizes and taking histological outcomes into consideration must be conducted to generate stronger evidence.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44261959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Vatakantaka (Plantar Fasciitis) with Agnikarma-A Case Study","authors":"Bhuvaneshwar A, S. K, Gayathri Sulochana","doi":"10.47552/ijam.v14i2.3180","DOIUrl":"https://doi.org/10.47552/ijam.v14i2.3180","url":null,"abstract":"Acharya Sushruta explained that when a person walk on the irregular or uneven surface, vata gets localized and aggravated in khuda pradesha (Ankle joint) and produce pain in heal region known as Vatakantaka. It can be compared to Plantar Fasciitis.  Plantar Fasciitis is the one of the painful condition in heel that hampers daily activity. Plantar Fasciitis is caused due to repeated stretch and strain of plantar fascia resulting in injury and inflammation which produces heel pain. Plantar fasciitis is managed with analgesic and anti-inflammatory, intra articular steroid injection and surgically by plantar fascia release as per requirement, but such type of treatment increased hospital stay and high economical expenses. Sushruta mentioned agnikarma in management of Vatakantaka which can be done with less economical expenditure and minimum hospitalization. Agnikarma is used in this case study to assess its efficacy in relieving pain. 46 years old female complaints of right heel pain in first few steps in morning and pain relived after walking, and again pain developed after prolonged period of rest. Patient was treated by Samyak Bindu vat Agnikarma at ankle region in 4 sittings at the interval of 7 days, which given complete relief from pain. ","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46171529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular docking analysis of selected bioactive components of Glycyrrhiza glabra against bronchial asthma","authors":"Nandhini E, Chakravarthi P, K. S, M. S","doi":"10.47552/ijam.v14i2.3415","DOIUrl":"https://doi.org/10.47552/ijam.v14i2.3415","url":null,"abstract":"Bronchial asthma is a chronic inflammatory disease of the lung by the combined action of various cytokines. As a result of the strong inflammatory response increased infiltration of cytokines result, damages respiratory epithelium, Hyperplasia of the trachealis muscle, and increased mucous production. Athimathura choornam is a promising drug used in all inflammatory conditions. Objective:  To explore the efficacy of the Siddha formulation Athimathura choornam, an anti asthmatic drug using computational molecular docking analysis. Method: Based on the phytochemical study the active principles present in the plant Athimathuram were retrieved. 3D structure of the targets were retrieved from the repository and purified before the initiation of docking using the software. The potency of the drug was screened based on the binding of the ligands Asparagine, Liquiritin, and Glabridin with targets mentioned. These results were compared with the standard drugs such as Cetirizine, Salicylic acid, Diclofenac, Ibuprofen, and Celecoxib. Results and Conclusion: Liquiritin has 9 interactions (90%) similar to that of Ibuprofen, 14 interactions (90%) similar to that of  Citrazinehence , 5 interactions (100%) similar to that of salicylic acid hence it has promising COX 1 inhibition ,Histamine 1 blocking activity and Prostaglandin Synthase inhibition activity. Asparagine has 3 interactions (60%) similar to Celecoxib, has promising COX 2 inhibition activity. Glabridin has 2 interactions (50%) similar to that of Diclofenac hence it has promising IL6 inhibition activity. ","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46523175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective clinical study to evaluate efficacy of Vasantkusumakar Rasa (Herbomineral preparation) on Psychological health of patients of Madhumeha (Diabetes Mellitus)","authors":"Sudarshan Hande, Amit Mujumdar, Kavita Turambekar Hande, Anjali Hingane, Smita Dhurde","doi":"10.47552/ijam.v14i2.3440","DOIUrl":"https://doi.org/10.47552/ijam.v14i2.3440","url":null,"abstract":"Diabetes Mellitus although a modern terminology it has been known to mankind since long through ancient Ayurvedic treatises with name Prameha (Diabetes). As the incidence & prevalence of DM with complications along with its ill effects on psychological health is growing rapid. Due to Consistent stress blood sugar control becomes difficult. So, to search a drug which may improve psychological health is need of an hour. Vasantkusumakar Rasa is one of such drugs mentioned in Ayurveda compendia as treatment protocol of Prameha (Diabetes) also the one which is reputed for its rejuvenating property. This Herbomineral composition is also known to improve psychological health. Its efficacy to improve psychological state in patients of DM i.e. Madhumeha (DM) is evaluated in this study. Herbomineral compound i.e. Vasantkusumakar Ras 125mg two times a day with Luke warm water before meal for one month to 37 patients in experimental group as a add on therapy in continuation to their standard medicines. In control group 31 patients were continued their regular standard protocol medicines for DM. To study the effect of drug following parameters were analyzed on 0th day and on 30th day of study. Parameters included for study are Blood sugar level, Symptoms of Madhumeha (DM), Manas Bhav (Psychological traits) and psychiatric rating scale. These parameters show significant improvement in experimental group but no such effect was found in Control group.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47667206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applied aspects of Dincharya – The Daily Regimen as per Ayurveda, directing towards health maintenance and disease prevention in present era","authors":"Sheetal G. Asutkar, Yogesh Yadav, V. Asutkar","doi":"10.47552/ijam.v14i2.3578","DOIUrl":"https://doi.org/10.47552/ijam.v14i2.3578","url":null,"abstract":"Introduction- Dinacharya means an ideal daily regimen as per Ayurveda that offers a lifestyle with beneficial physiological and psychological effects for a human body and mind. Why is it called ideal is because it harmonizes balance between body humors(Dosha),tissues(Dhatu) and wastes (Mala) power of digestion(Agni), grooms a pleasant mind, soul and sense organs and offers disease free long life. This is how health is defined by Sushruta Acharya. This idealism needs also to be understood through conceptual justification from Ayurveda. Dinacharya includes activities such waking in Bramha-muhurta (45min before sunrise), brushing teeth-Dantadhawana, Tongue cleaning-Jihva-Nirlekhan, applying corrylium-Anjana, Nasal drops-Nasya, Oilpulling-Kavala, Medicated gargles-Gandusha, Oil massaging-Abhyanga, Exercise-Vyayama, Powder massage-Udvartana, Bathing-Snana, righteous conduct-Sadvrutta and Bhojana-Rules for food consumption etc. Disregarding them have increased the ratio of non-communicable diseases, idiopathic diseases and lifestyle induced diseases like hypertension, diabetes, cardio-vascular diseases etc. Treatment options like anti-hypertensive drugs, anti-diabetic drugs, blood thinning agents etc, are expensive and have adverse reactions. Also invasive methods are preferred by people with fear of obligation for lifelong medications. This is leading to decrease in quality of life. The conceptual and applied explorative understanding of term ‘ideal’ and applying it with regimen of Dinacharya, can be aptly used to prevent above diseases in population today. Aim- To achieve health maintenance and disease prevention by obeying ideal Dinacharya. Objective-To understand the conceptual logic of idealness of a regimen and explore methods of ideal Dinacharya and justify their utility through updated researches. Materials and methods- Collecting and analyzing data from Google Scholar, PubMed, Scopus etc. Results- In Bramha-Muhurta Cortisol hormone is at its peak in 30 minutes post waking, responsible for anti-stress activity, immune-modulation and metabolic enhancement. Kavala/Gandusha decreases the plaque, gingival scores and the number of bacteria. Abhyanga normalises circadian rhythm by action on tryptophan and serotonin levels. Vyayama-studies shows that it is effective in Alzheimer’s disease, decreases blood pressure in HTN patients, decreases HbA1C in type-2 DM patients and decreases cardiovascular disease. Nasya has helped in preventing URTI and allied severe symptoms ex-COVID19, Discussion- weak immunity causes communicable diseases and disturbed metabolism causes non-communicable diseases. Conclusion -Following ideal regimen through Dinacharya activities timely corrects both these health aspects. \u0000Keywords- Dinacharya, Non-Communicable disease, Communicable disease, Diabetes, Hypertension","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43434600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of Hand Index with Prakriti:  A Cross -Sectional Study","authors":"Amrish Chanana, Dattu Bandapalle","doi":"10.47552/ijam.v14i2.3541","DOIUrl":"https://doi.org/10.47552/ijam.v14i2.3541","url":null,"abstract":"Introduction: Based on the measurements of the body, the constitution and physique of an individual can be classified as ectomorph, mesomorph, and endomorph body types (somaotypes). Similarly, the knowledge of anthropometry can be made applicable in the assessment of Deha Prakriti, described in Ayurveda. Somatometry, a division of anthropometry includes direct surface measurements of the human body by scientific methods. Analysis and comparison of the absolute measurements of body parts do not give a precise idea about the individual typology of the subject, so it is necessary to work out the relevant indices, so variation in hand index between the different groups of dominant Prakriti has been observed. Methodology: Two hundred apparently healthy male individuals of age 18-40 years were registered from the population residing in Delhi. Prakriti of the study participants was assessed through the questionnaire. The length and breadth of both the hands were measured by the digital sliding caliper. The hand index is calculated as the percentage of the breadth of hand to the length of hand. The difference in the values of the hand index in different groups of dominant Prakriti was statistically analyzed by appropriate statistical tests. Result: The receiver operating characteristic (ROC) analysis showed the value of right hand index in different dominant Prakriti as Vata dominant <= 41.344, 41.344 <  Pitta dominant < 43.930, Kapha dominant>=43.930, whereas in left hand, the value of hand index in Vata dominant  <= 41.895, 41.895 <  Pitta dominant < 43.687, Kapha dominant>=43.687. Conclusion: There are significant differences in the hand index among different Deha Prakriti. ","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48279709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study on development and quality analysis of a beverage incorporated with Terminalia chebula","authors":"Itisha Dhamija, D. Puri","doi":"10.47552/ijam.v14i2.3622","DOIUrl":"https://doi.org/10.47552/ijam.v14i2.3622","url":null,"abstract":"The study’s aim was to develop a beverage incorporated with Terminalia chebula Retz., locally known as Haritaki, having gastro-intestinal motility improving properties. The objectives of the study were to develop the beverage, check its acceptability by conducting sensory evaluation and chemically analyzing the beverage for quality assessment by testing its anti-oxidant properties and presence of gallic acid, i.e., a hydrolysable tannin present in Haritaki fruit which majorly possess the properties of improving gastro-intestinal motility. The beverage was made by two methods viz. overnight refrigeration and boiling method. Then sensory evaluation was conducted by 9-point hedonic scale and as a result of which sample made with overnight refrigeration method were found to be more acceptable. Then samples prepared with both the methods were subjected to antioxidant property test and High-performance liquid chromatography (HPLC) to check the presence of gallic acid. The test results were in favor of the sample prepared by overnight refrigeration method having 14.49% more antioxidant property and 26.06mg/kg more gallic acid than that of the sample prepared with boiling method. The original taste of Haritaki is very bitter and strong. So, with the development of this beverage the flavor of Haritaki is enhanced and bitterness is reduced. Therefore, consumers can opt for this beverage over the original powdered form, hence increasing the acceptability of Haritaki. Also, no further preparation is required, people can consume it at an ease. The beverage developed will be a boon to the food industry in this era of unhealthy lifestyle. ","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46989626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A clinical study on the management of Arshas (Prolapsed Piles) by Jaloukavacharana","authors":"Udaya Kiran T, A. Menon, Mugilmathi B K","doi":"10.47552/ijam.v14i2.3487","DOIUrl":"https://doi.org/10.47552/ijam.v14i2.3487","url":null,"abstract":"Background: Arshas is one among the Mahagadas (major diseases) which causes pain and obstruction in the anal passage. It is a rakta and mamsa doshaja vyadhi (disease related to blood and muscle). Arshas can be correlated to hemorrhoids. It is caused due to the varicosity of hemorrhoidal plexus which makes it a surgically curable disease. In Ayurveda, various treatments have been mentioned for the management of arshas (hemorrhoid) such as chedhana (excision), sweda (sudation), etc among which Visravana or raktamokshana (blood-letting therapy) plays an important role. Jalaukavacharana (leech therapy), a type of Asashtra krita Visravana (non-invasive blood-letting) has been mentioned as an alternate, non-surgical measure in the management of arshas (hemorrhoid). The arshas (hemorrhoids) which are swollen, prolapsed and containing more quantum of stagnated blood inside can be managed by leech therapy. The saliva of leech contains an anti-coagulant factor – Hirudin and a spreading factor – Hyaluronidase, which act as anesthetic and anti-inflammatory, thereby helping in the treatment of arshas (hemorrhoid). In the present study, raktamokshana (blood letting) was performed with jalauka or leech in patients with prolapsed pile mass. Materials and method: 30 patients fulfilling the assessment criteria were selected for the study. Result and conclusion: In the present study 26 patients were completely cured, 3 patients were cured with presence of mild symptoms and 1 patient had improvement from severe symptoms to moderate symptoms. Therefore, Jalaukavacharana (leech therapy) can give promising results in the management of prolapsed piles.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43183534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report study on long term follow up treatment of T-AYU-HM Premium in Sickle cell anaemia Patient","authors":"Atul Desai, K. Desai, Hemshree Desai, R. Desai, Chirag V Desai","doi":"10.47552/ijam.v14i2.3348","DOIUrl":"https://doi.org/10.47552/ijam.v14i2.3348","url":null,"abstract":"Sickle cell anaemia is a haemoglobin condition for which the Indian government has set up particular support provisions within the ministry of tribal affairs. Despite epidemiological and recent advances in the treatment of sickle cell anaemia over the past few years, it remains a global concern for everyone. To demonstrate the impact of T-AYU-HM Premium, the long-term treatment outcomes of a patient with sickle cell trait are detailed in this case study. A 35-year-old female patient with a family history of sickle cell anaemia was unable to finish her studies because she had blood transfusions every other month and experienced excruciating pain. Her reported painful crises, treatment compliance, the number of blood transfusions she received, and the number of hospitalizations she needed were all reviewed in this case study. Her past medication and medical history were assessed in 2008 following which the T-AYU-HM Premium treatment was started once she approached the clinic with these complaints. It was noted that the patient followed the prescribed line of treatment, had symptomatic relief from episodic pain, and was able to perform day-to-day tasks. It was noted that the patient only required one blood transfusion and one hospital stay throughout the course of the 15 years of follow-up. This case study would further the understanding and practical application of complementary medicine in the treatment of sickle cell anaemia. The potential for long-term treatment using alternative medical systems may well be established. ","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47754396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myths and Facts about Diet (Ahaar) in Today’s Era","authors":"Kusum, Satnam Singh","doi":"10.47552/ijam.v14i2.3164","DOIUrl":"https://doi.org/10.47552/ijam.v14i2.3164","url":null,"abstract":"In Ayurveda, diet has been given a great importance and is referred as Mahabhaisjaya in Ayurveda classics. Bhaisjaya means medicine or any substance that cure body, means diet is not only to satisfy hunger of Ahaara, but it also acts as medicine i.e., build and cure the body. The distinction between health and disease is correlated with wholesome and unwholesome diet because both body and disease are the product of food. There is urgent need to have knowledge about real facts and burst myths about food items. Ayurveda has its own unique approach to Planning a daily diet for an individual. It is not based on conventional chemistry; rather, it is based on Panchmahabhautic chemistry and Tridoshic functions. In Ayurveda, Annapanavidhi can be correlated with dietetics. It incorporates the concept of Pathya-Apathya, the natural characteristics of different food items and the dietary guidelines which leads towards sound health. According to Ayurvedic classics One type of food can’t be benefited for different type of people. There are many variations like Prakriti, Desh, Kaal, Agni etc. Digestion of Ahara and Poshan by Ahara is based on many factors. It’s not like modern science reduced to calories or in term of carbohydrates, proteins, fats etc. only. Unhealthy diet practice is considered as one of the important reasons of disease. Hence the correction of diet itself is considered as treatment. Without this knowledge our food is worthless even after we consume a very high-quality food. So, there is an effort to put some light on facts and myths about food in today lifestyle by this paper.","PeriodicalId":13751,"journal":{"name":"International Journal of Ayurvedic Medicine","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47885278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}