Pub Date : 2023-04-15DOI: 10.18231/j.ijmmtd.2023.008
K. Nirmal, Priyanka Gupta, N. Singh, V. Misra
Neonatal Mortality Rate (NMR) is one of the indicators of health status of a nation and neonatal sepsis is one of the commonest causes of NMR contributing to 19% of all neonatal deaths in India. All over India, there is a gradually increasing trend of multi-drug resistant (MDR) pathogens in neonatal intensive care units (NICU) and special newborn care units (SNCUs) in tertiary care hospitals.To determine the changing trend in the bacteriological profile of neonatal septicemia and their antibiotic susceptibility pattern (AST).It is a retrospective study conducted on total 452 blood culture samples collected from SNCU over 1-year period from July 2017 to June 2018 in tertiary care government hospital. Organisms were identified by the standard protocol and their antimicrobial susceptibility testing was determined as per latest CLSI guidelines.out of 452 blood culture of neonatal septicemia patients, 138 cases (30.53%) were culture positive Most common isolated gram negative organism was spp. 55/138 (39.85%) followed by spp. 23/138 (16.66%). Most common isolated gram positive organism was 25/138 (18.11%) followed by Coagulase Negative Staphylococcus (CONS) (8.69%). Among gram negative isolates most sensitive antimicrobial was Imipenem (87.6%) followed by Levofloxacin (87.4%) and Piperacillin + Tazobactam (46%) and resistant to, Cotrimoxazole, Amoxicillin + clavulanate and 3rd generation Cephalosporins.spp. is the predominant organism of neonatal sepsis in the Indian subcontinent, although significant rise in proportion of spp. is occurring. High resistance to cephalosporins is a cause of concern, as they are one of the most common prescribed antibiotic groups.
{"title":"The changing bacteriological profile of neonatal sepsis in a tertiary care hospital – Emergence of Citrobacter septicemia","authors":"K. Nirmal, Priyanka Gupta, N. Singh, V. Misra","doi":"10.18231/j.ijmmtd.2023.008","DOIUrl":"https://doi.org/10.18231/j.ijmmtd.2023.008","url":null,"abstract":"Neonatal Mortality Rate (NMR) is one of the indicators of health status of a nation and neonatal sepsis is one of the commonest causes of NMR contributing to 19% of all neonatal deaths in India. All over India, there is a gradually increasing trend of multi-drug resistant (MDR) pathogens in neonatal intensive care units (NICU) and special newborn care units (SNCUs) in tertiary care hospitals.To determine the changing trend in the bacteriological profile of neonatal septicemia and their antibiotic susceptibility pattern (AST).It is a retrospective study conducted on total 452 blood culture samples collected from SNCU over 1-year period from July 2017 to June 2018 in tertiary care government hospital. Organisms were identified by the standard protocol and their antimicrobial susceptibility testing was determined as per latest CLSI guidelines.out of 452 blood culture of neonatal septicemia patients, 138 cases (30.53%) were culture positive Most common isolated gram negative organism was spp. 55/138 (39.85%) followed by spp. 23/138 (16.66%). Most common isolated gram positive organism was 25/138 (18.11%) followed by Coagulase Negative Staphylococcus (CONS) (8.69%). Among gram negative isolates most sensitive antimicrobial was Imipenem (87.6%) followed by Levofloxacin (87.4%) and Piperacillin + Tazobactam (46%) and resistant to, Cotrimoxazole, Amoxicillin + clavulanate and 3rd generation Cephalosporins.spp. is the predominant organism of neonatal sepsis in the Indian subcontinent, although significant rise in proportion of spp. is occurring. High resistance to cephalosporins is a cause of concern, as they are one of the most common prescribed antibiotic groups.","PeriodicalId":14553,"journal":{"name":"IP International Journal of Medical Microbiology and Tropical Diseases","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82773250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-15DOI: 10.18231/j.ijmmtd.2023.011
S. Bhattacharyya, T. Das, S. Datta, A. Banik
Probiotics are very important for our daily life and as food. However, they must be safe to consume. There can be many bacterial contaminants present in curd bought from the market, which can cause infections. We studied curd samples and found many such pathogens as well as Acid fast bacilli. Hence, one should be cautious while consuming curd bought from market. This is an important but neglected area of public health research.
{"title":"Study of normal and pathogenic bacteria and yeasts in curd samples","authors":"S. Bhattacharyya, T. Das, S. Datta, A. Banik","doi":"10.18231/j.ijmmtd.2023.011","DOIUrl":"https://doi.org/10.18231/j.ijmmtd.2023.011","url":null,"abstract":"Probiotics are very important for our daily life and as food. However, they must be safe to consume. There can be many bacterial contaminants present in curd bought from the market, which can cause infections. We studied curd samples and found many such pathogens as well as Acid fast bacilli. Hence, one should be cautious while consuming curd bought from market. This is an important but neglected area of public health research.","PeriodicalId":14553,"journal":{"name":"IP International Journal of Medical Microbiology and Tropical Diseases","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80879196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-15DOI: 10.18231/j.ijmmtd.2023.012
Tulika Mishra
Invasive meningococcal disease caused by is a serious disease that is deadly in 5–15% and incapacitating in 12–20% of cases. There are twelve strains known so far, out of which six serogroups (A, B, C, W, X, and Y) have been found to cause Invasive meningococcal disease. Infection can cause meningitis, septicemia, bacteremic pneumonia, and bacteremia without focus and can cause long-term disability. Outbreaks of meningococcal disease are rare in the United States but recently outbreak has declared in Florida by the Centers for Disease Control and Prevention. To study the pattern of Meningococcal infection from 2010-2020 in the United States. All analyses for this cross-sectional study were conducted using Bact Facts Interactive which collects data from Active Bacterial Core surveillance (ABCs), a part of CDC’s Emerging Infections Program All the data for percentage cases of bacteremia & pneumonia, percentage cases of bacteremia without focus, Meningitis, and total case rate of infection declined down from 2010 to 2020.The present study highlights that in the United States due to strict vaccination, surveillance, and usage of antibiotics at the appropriate time, the cases of infection declined to a greater extent.
{"title":"Evaluation of the rate of Neisseria meningitides Infection in the United States from 2010 to 2020","authors":"Tulika Mishra","doi":"10.18231/j.ijmmtd.2023.012","DOIUrl":"https://doi.org/10.18231/j.ijmmtd.2023.012","url":null,"abstract":"Invasive meningococcal disease caused by is a serious disease that is deadly in 5–15% and incapacitating in 12–20% of cases. There are twelve strains known so far, out of which six serogroups (A, B, C, W, X, and Y) have been found to cause Invasive meningococcal disease. Infection can cause meningitis, septicemia, bacteremic pneumonia, and bacteremia without focus and can cause long-term disability. Outbreaks of meningococcal disease are rare in the United States but recently outbreak has declared in Florida by the Centers for Disease Control and Prevention. To study the pattern of Meningococcal infection from 2010-2020 in the United States. All analyses for this cross-sectional study were conducted using Bact Facts Interactive which collects data from Active Bacterial Core surveillance (ABCs), a part of CDC’s Emerging Infections Program All the data for percentage cases of bacteremia & pneumonia, percentage cases of bacteremia without focus, Meningitis, and total case rate of infection declined down from 2010 to 2020.The present study highlights that in the United States due to strict vaccination, surveillance, and usage of antibiotics at the appropriate time, the cases of infection declined to a greater extent.","PeriodicalId":14553,"journal":{"name":"IP International Journal of Medical Microbiology and Tropical Diseases","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82288137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-15DOI: 10.18231/j.ijmmtd.2023.003
H. Ouédraogo, Pascal Nabia, K. Cissé, O. Ouédraogo, A. Zouré, Danielle Belemsaga Yugbare, Sylvie Zida, E. Diendéré, T. Sagna
This study aimed to evaluate the correlation between suspected COVID-19 symptoms and RT-PCR results in the diagnosis of SARS-CoV-2 infection in Burkina Faso. We analyzed SARS-CoV-2 RT-PCR routine diagnostic data in Burkina Faso. Data were collected from March 9, 2020 to September 30, 2020 in the framework of the COVID-19 surveillance. Sensitivity, specificity, predictive values, and Kappa concordance were used to check the correlation between COVID-19 symptoms and the RT-PCR results. A total of 2217 participants were tested for COVID-19 using RT-PCR, of them 779 COVID-19 positive. The mean age of the participants was 38.7± 17.69 years. Suspected symptoms presented by participants were fever (40.4%), cough (38.6%), asthenia (27.3%), headache (23.6%), dyspnea (20.8%), and odynophagia (16.3%). The sensitivity of presence of at least a clinical sign compared to RT-PCR results was 62.13% and the specificity was 39.85%. The kappa agreement between the presence of COVID-19 suspected symptoms and RT-PCR results was 0.017. The presence of aguesia and/or anosmia in patients induced a positive predictive value of RT-PCR of 91.30%. : The correlation between the COVID-19 symptoms and RT-PCR results in the diagnosis of COVID-19 was very weak. The present study confirms that most clinical signs associated with SARS-CoV-2 infection are not specific to COVID-19, hence the need to always combine RT-PCR or other biological tests with the clinical diagnosis. However, aguesia and anosmia are of interest with a high degree of RT-PCR positivity when present in a COVID-19 suspected patient.
{"title":"Correlation between clinical symptomatology and RT-PCR results in the diagnosis of COVID-19: An analysis using routine data in Burkina Faso","authors":"H. Ouédraogo, Pascal Nabia, K. Cissé, O. Ouédraogo, A. Zouré, Danielle Belemsaga Yugbare, Sylvie Zida, E. Diendéré, T. Sagna","doi":"10.18231/j.ijmmtd.2023.003","DOIUrl":"https://doi.org/10.18231/j.ijmmtd.2023.003","url":null,"abstract":"This study aimed to evaluate the correlation between suspected COVID-19 symptoms and RT-PCR results in the diagnosis of SARS-CoV-2 infection in Burkina Faso. We analyzed SARS-CoV-2 RT-PCR routine diagnostic data in Burkina Faso. Data were collected from March 9, 2020 to September 30, 2020 in the framework of the COVID-19 surveillance. Sensitivity, specificity, predictive values, and Kappa concordance were used to check the correlation between COVID-19 symptoms and the RT-PCR results. A total of 2217 participants were tested for COVID-19 using RT-PCR, of them 779 COVID-19 positive. The mean age of the participants was 38.7± 17.69 years. Suspected symptoms presented by participants were fever (40.4%), cough (38.6%), asthenia (27.3%), headache (23.6%), dyspnea (20.8%), and odynophagia (16.3%). The sensitivity of presence of at least a clinical sign compared to RT-PCR results was 62.13% and the specificity was 39.85%. The kappa agreement between the presence of COVID-19 suspected symptoms and RT-PCR results was 0.017. The presence of aguesia and/or anosmia in patients induced a positive predictive value of RT-PCR of 91.30%. : The correlation between the COVID-19 symptoms and RT-PCR results in the diagnosis of COVID-19 was very weak. The present study confirms that most clinical signs associated with SARS-CoV-2 infection are not specific to COVID-19, hence the need to always combine RT-PCR or other biological tests with the clinical diagnosis. However, aguesia and anosmia are of interest with a high degree of RT-PCR positivity when present in a COVID-19 suspected patient.","PeriodicalId":14553,"journal":{"name":"IP International Journal of Medical Microbiology and Tropical Diseases","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83081515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-15DOI: 10.18231/j.ijmmtd.2023.006
S. Bhattacharyya, Sri Krishna Vinay Triparagiri, Subhrajeet Chakraborty, A. Banik, Atul Raj
Parasitic infections of the gut are difficult to detect. It depends on microscopy and also different concentration techniques. All the concentration techniques may not be good and may not give reproducible results. Though there are some standard solutions giving good results but they are not always affordable in all geographical areas and there are very less solutions able to detect parasitic ova in both soil and faeces. We here report a new concentration technique i.e. sugar-ethanol solution for gut parasites. In this study we compared our novel solution (sugar ethanol) with saturated salt solution by flotation technique in the dung sample of cattle and soil samples around them in rural area of West Bengal. Results were conformable and new sugar-akcohol based solution was superior to Saturated saline. This solution can be used for concentration technique in stool samples.
{"title":"A study on prevalence of Intestinal worm infestation and a comparative analysis between two floatation methods, for demonstrating intestinal parasites in stool (dung) of cattle","authors":"S. Bhattacharyya, Sri Krishna Vinay Triparagiri, Subhrajeet Chakraborty, A. Banik, Atul Raj","doi":"10.18231/j.ijmmtd.2023.006","DOIUrl":"https://doi.org/10.18231/j.ijmmtd.2023.006","url":null,"abstract":"Parasitic infections of the gut are difficult to detect. It depends on microscopy and also different concentration techniques. All the concentration techniques may not be good and may not give reproducible results. Though there are some standard solutions giving good results but they are not always affordable in all geographical areas and there are very less solutions able to detect parasitic ova in both soil and faeces. We here report a new concentration technique i.e. sugar-ethanol solution for gut parasites. In this study we compared our novel solution (sugar ethanol) with saturated salt solution by flotation technique in the dung sample of cattle and soil samples around them in rural area of West Bengal. Results were conformable and new sugar-akcohol based solution was superior to Saturated saline. This solution can be used for concentration technique in stool samples.","PeriodicalId":14553,"journal":{"name":"IP International Journal of Medical Microbiology and Tropical Diseases","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87283664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-15DOI: 10.18231/j.ijmmtd.2023.007
Roshni Vaheeda Salahudeen, Sim S.M., Geetha Bhai
Dermatophtyosis is common, more prevalent in tropical and subtropical countries including India. Though not life threatening it can cause great discomfort, especially in immunocompromised conditions. In the last few years a number of new less toxic antifungal drugs have become available for clinical use. Lack of clinical response may occur in 20%.125 clinically suspected cases of dermatophytosis were studied.The samples were subjected to direct microscopy and culture. Identification of the causative pathogen was done by performing slide culture, lacto phenol cotton blue mount, hair perforation tests and urease tests. In this study we evaluated the efficacy of seven antifungal medications using CLSI broth microdilution method (M38-A). The antifungals used were sertaconazole, terbinafine, griseofulvin, fluconazole, itraconazole, voriconazole and amphotericin B.Out of 125 samples, dermatophytosis manifested clinically more in the age group of 21-30 yrs. In our study, KOH positivity rate was 60.8% and culture positivity rate was 32%. Dermatophytosis was more common in females. Tinea corporis was the most common lesion (54.4%) followed by Tinea cruris (25.6%), Tinea pedis (8%), Tinea unguium(7.2%) and Tinea faciei (0.8%). was the commonest aetiological agent (50%) followed by (35%), (7.5%), (5%) and (2.5%). The range of their minimum inhibitory concentration endpoint by broth microdilution technique for the seven antifungal drugs were as follows, sertoconazole <0.06-4 μg/ml , griseofulvin 0.25-1 μg/ml, terbinafine <0.06-2 μg/ml, voriconazole 0.06-0.5 μg/ml, itraconazole <0.06-1 μg/ml, fluconazole 2-8 μg/ml and amphotericin B 2-8 μg/ml. This study gives an insight about the aetiological agents of dermatophytosis in this part of South Kerala, India. Both direct microscopy and culture are important tools for diagnosis of the superficial fungal infections. Majority of strains in the study were inhibited by relatively low concentration of the antifungals tested.
{"title":"Isolation, identification and antifungal susceptibility of dermatophytes from clinical specimens in a tertiary care hospital in South Kerala","authors":"Roshni Vaheeda Salahudeen, Sim S.M., Geetha Bhai","doi":"10.18231/j.ijmmtd.2023.007","DOIUrl":"https://doi.org/10.18231/j.ijmmtd.2023.007","url":null,"abstract":"Dermatophtyosis is common, more prevalent in tropical and subtropical countries including India. Though not life threatening it can cause great discomfort, especially in immunocompromised conditions. In the last few years a number of new less toxic antifungal drugs have become available for clinical use. Lack of clinical response may occur in 20%.125 clinically suspected cases of dermatophytosis were studied.The samples were subjected to direct microscopy and culture. Identification of the causative pathogen was done by performing slide culture, lacto phenol cotton blue mount, hair perforation tests and urease tests. In this study we evaluated the efficacy of seven antifungal medications using CLSI broth microdilution method (M38-A). The antifungals used were sertaconazole, terbinafine, griseofulvin, fluconazole, itraconazole, voriconazole and amphotericin B.Out of 125 samples, dermatophytosis manifested clinically more in the age group of 21-30 yrs. In our study, KOH positivity rate was 60.8% and culture positivity rate was 32%. Dermatophytosis was more common in females. Tinea corporis was the most common lesion (54.4%) followed by Tinea cruris (25.6%), Tinea pedis (8%), Tinea unguium(7.2%) and Tinea faciei (0.8%). was the commonest aetiological agent (50%) followed by (35%), (7.5%), (5%) and (2.5%). The range of their minimum inhibitory concentration endpoint by broth microdilution technique for the seven antifungal drugs were as follows, sertoconazole <0.06-4 μg/ml , griseofulvin 0.25-1 μg/ml, terbinafine <0.06-2 μg/ml, voriconazole 0.06-0.5 μg/ml, itraconazole <0.06-1 μg/ml, fluconazole 2-8 μg/ml and amphotericin B 2-8 μg/ml. This study gives an insight about the aetiological agents of dermatophytosis in this part of South Kerala, India. Both direct microscopy and culture are important tools for diagnosis of the superficial fungal infections. Majority of strains in the study were inhibited by relatively low concentration of the antifungals tested.","PeriodicalId":14553,"journal":{"name":"IP International Journal of Medical Microbiology and Tropical Diseases","volume":"112 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79358767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-15DOI: 10.18231/j.ijmmtd.2023.002
R. Swaminathan, N. Kamath
Candida contains a wide range of organisms, and more than 17 different Candida species have been linked to human infections. Newer species are emerging and Candida albicans and other Species are re-emerging. Isolated strains showing increased antifungal resistance, which necessitates the need for new antifungal drugs. Candida Spp can cause a wide range of mycoses, including invasive candidiasis, which can be deep, widespread, and extremely painful. The majority of the time, it spreads by endogenous Candidaemia. They adhere to host tissues and medical equipment, form biofilms, and release enzymes that break down proteins. Conventional techniques and molecular techniques have made laboratory diagnosis of Candida easy. However, Candida infections are more common in immunocmpromised and hospitalised patients.
{"title":"Candida-An emerging and re-emerging pathogen","authors":"R. Swaminathan, N. Kamath","doi":"10.18231/j.ijmmtd.2023.002","DOIUrl":"https://doi.org/10.18231/j.ijmmtd.2023.002","url":null,"abstract":"Candida contains a wide range of organisms, and more than 17 different Candida species have been linked to human infections. Newer species are emerging and Candida albicans and other Species are re-emerging. Isolated strains showing increased antifungal resistance, which necessitates the need for new antifungal drugs. Candida Spp can cause a wide range of mycoses, including invasive candidiasis, which can be deep, widespread, and extremely painful. The majority of the time, it spreads by endogenous Candidaemia. They adhere to host tissues and medical equipment, form biofilms, and release enzymes that break down proteins. Conventional techniques and molecular techniques have made laboratory diagnosis of Candida easy. However, Candida infections are more common in immunocmpromised and hospitalised patients.","PeriodicalId":14553,"journal":{"name":"IP International Journal of Medical Microbiology and Tropical Diseases","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80906637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-15DOI: 10.18231/j.ijmmtd.2023.013
S. Bhat, Ashwin Venu, Jagadish K.L
is a beta-hemolytic Gram-positive, catalase-negative, nonmotile coccus arranged in short chains, usually found in the female genitourinary tract. Only a few human infections associated with this organism have been reported till date. is usually found as colonizer of female genital tract, has been rarely associated with bacteremia. We are reporting a rare case of causing bacteremia in patients with respiratory failure and coronary artery disease, who was treated with clindamycin and piperacillin/tazobactam. This case report illustrates the potential of these bacteria to cause severe invasive and life-threatening disease.
{"title":"Streptococcus pseudoporcinus bacteremia in a Type II-respiratory failure patient with coronary artery disease: A case report","authors":"S. Bhat, Ashwin Venu, Jagadish K.L","doi":"10.18231/j.ijmmtd.2023.013","DOIUrl":"https://doi.org/10.18231/j.ijmmtd.2023.013","url":null,"abstract":"is a beta-hemolytic Gram-positive, catalase-negative, nonmotile coccus arranged in short chains, usually found in the female genitourinary tract. Only a few human infections associated with this organism have been reported till date. is usually found as colonizer of female genital tract, has been rarely associated with bacteremia. We are reporting a rare case of causing bacteremia in patients with respiratory failure and coronary artery disease, who was treated with clindamycin and piperacillin/tazobactam. This case report illustrates the potential of these bacteria to cause severe invasive and life-threatening disease.","PeriodicalId":14553,"journal":{"name":"IP International Journal of Medical Microbiology and Tropical Diseases","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74300885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-15DOI: 10.18231/j.ijmmtd.2022.061
S. Pachpute, S. Jayalakshmi, A. Urhekar
Nosocomial Infections are the infections that are neither at incubating state nor present at the time of admission. They are greatly associated with Surgical procedures and Invasive Medical Devices and hence OTs and ICUs are known as ‘Hot Zones’ and Gram Negative and Gram-positive organisms are responsible. Hence, regular surveillance of these areas remains the mainstay to monitor the raising trend of nosocomial infections. To find out the prevalence of Bacteria and Bacterial load in Pre and Post fumigation swabs from various areas of Maternity and Children hospital like OTs, Patient Ward, Labor ward and NICUs and to test the effectiveness of the standard disinfectants. The swabs were collected from different areas of MGM Maternity and Children Hospital, Kalamboli Mumbai The swabs were further processed and organisms were identified using standard Microbiological procedures. The standard disinfectants were tested using Kelsey-Sykes Capacity test, and they “Passed” the test. Out of the total Pre fumigation swabs collected, growth was seen in 15% of the swabs while in Post fumigation swabs 3% of growth was seen. In places like Minor OT, Septic OT, Labor Room, Waiting Room a higher value of Chi-square test statistics indicated a statistically significant association between fumigation and growth of microorganisms. Majorly non-pathogenic organism like Bacillus was isolated followed by CoNS and few . Hence this indicates significant reduction in growth of microorganisms in majority of the areas of post fumigation swabs indicating following of proper infection control procedures. This study describes the profile of Bacterial Load in high-risk areas of Maternity and Children Hospital. Pre and post fumigation swabs were tested from high-risk areas including Minor OT, Major OT, Septic OT, Female Ward, Recovery Room, PNC, NICU. Also, suggestions were made to incorporate air sampling methods for better assessments. The knowledge of these findings and appropriate corrective measures can greatly impact the health of neonates as well as the mothers.
{"title":"Infection control measures at maternity and children hospital and data analysis","authors":"S. Pachpute, S. Jayalakshmi, A. Urhekar","doi":"10.18231/j.ijmmtd.2022.061","DOIUrl":"https://doi.org/10.18231/j.ijmmtd.2022.061","url":null,"abstract":"Nosocomial Infections are the infections that are neither at incubating state nor present at the time of admission. They are greatly associated with Surgical procedures and Invasive Medical Devices and hence OTs and ICUs are known as ‘Hot Zones’ and Gram Negative and Gram-positive organisms are responsible. Hence, regular surveillance of these areas remains the mainstay to monitor the raising trend of nosocomial infections. To find out the prevalence of Bacteria and Bacterial load in Pre and Post fumigation swabs from various areas of Maternity and Children hospital like OTs, Patient Ward, Labor ward and NICUs and to test the effectiveness of the standard disinfectants. The swabs were collected from different areas of MGM Maternity and Children Hospital, Kalamboli Mumbai The swabs were further processed and organisms were identified using standard Microbiological procedures. The standard disinfectants were tested using Kelsey-Sykes Capacity test, and they “Passed” the test. Out of the total Pre fumigation swabs collected, growth was seen in 15% of the swabs while in Post fumigation swabs 3% of growth was seen. In places like Minor OT, Septic OT, Labor Room, Waiting Room a higher value of Chi-square test statistics indicated a statistically significant association between fumigation and growth of microorganisms. Majorly non-pathogenic organism like Bacillus was isolated followed by CoNS and few . Hence this indicates significant reduction in growth of microorganisms in majority of the areas of post fumigation swabs indicating following of proper infection control procedures. This study describes the profile of Bacterial Load in high-risk areas of Maternity and Children Hospital. Pre and post fumigation swabs were tested from high-risk areas including Minor OT, Major OT, Septic OT, Female Ward, Recovery Room, PNC, NICU. Also, suggestions were made to incorporate air sampling methods for better assessments. The knowledge of these findings and appropriate corrective measures can greatly impact the health of neonates as well as the mothers.","PeriodicalId":14553,"journal":{"name":"IP International Journal of Medical Microbiology and Tropical Diseases","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84727532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-15DOI: 10.18231/j.ijmmtd.2022.066
Jyoti Tomar, N. Goyal, K. Jangid
Mycetoma is a chronic granulomatous infection of cutaneous and subcutaneous tissues caused by filamentous bacteria (actinomycetoma) or fungi (eumycetoma). The most common site of infection is the foot, followed by the hand, but sometimes other body parts may also be infected. The patients present with a painless hard and swelling subcutaneous mass, multiple sinuses, and the pathognomonic discharge of grains. A 42-year-old male patient, presented pain and swelling in his right hand and also complained of swelling in his right forearm. The swelling later involved his whole right hand and wrist joint. Physical examination revealed multiple discharging sinuses with serosanguineous exudates and black grains. Swelling and local erythema were present, lymph nodes were not palpable. The patient complained of constant mild pain which is relieved by pain medications. The serohematic discharge was witnessed with conglomerates of small and firm blackish pellets, evoking eumycetomaSaline dressing was applied overnight and next morning grains were directly collected from sinuses. Tissue and black grain samples were analyzed for bacterial and mycological evaluation. Direct microscopy was performed using Gram stain showed thicker hyphae of eumycetoma. Modified ZN stain showed no acid fast bacilli. LPCB was helpful in confirming thicker hyphae of eumycetoma. Here, on clinical diagnosis (classical triad that is, painless soft tissue swelling, draining sinuses and extrusion of grains) with microbiological investigation, we concluded it a case of “Eumycetoma”.
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