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Remerciements aux rédacteurs adjoints et aux experts 感谢助理编辑和专家
IF 1.1 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2026-01-30 DOI: 10.1016/j.jfo.2026.104787
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引用次数: 0
Anterior Segment Changes after Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) in Pseudophakic Patients with Open-angle Glaucoma 假性晶状体伴开角型青光眼患者经腔内小梁切开术后前段的变化。
IF 1.1 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-12-12 DOI: 10.1016/j.jfo.2025.104727
F.I. Sozen-Delil, R. Donmez Gun
<div><h3>Purpose</h3><div>We aimed to evaluate the anterior segment parameters and refractive changes after Gonioscopy-Assisted Transluminal Trabeculotomy (GATT).</div></div><div><h3>Materials and methods</h3><div>This retrospective, cross-sectional, observational study included 21 eyes of 19 patients with open-angle glaucoma who underwent at least 180° GATT between February 2022 and January 2024. The anterior segment parameters obtained using Sirius corneal topography (CSO, Italy) were retrospectively reviewed for the preoperative period and the 3rd postoperative month.</div></div><div><h3>Results</h3><div>Among the study population, fourteen eyes were diagnosed with primary open-angle glaucoma, six with pseudoexfoliative glaucoma, and one with pigmentary glaucoma. Compared to the preoperative period, the postoperative intraocular pressure (IOP) and the number of antiglaucomatous drugs (NAGD) used were significantly lower (23 [15–35] mmHg vs. 14 [7–19] mmHg, <em>P</em> <!--><<!--> <!-->0.001; 4 [1–4] vs. 0 [0–3], <em>P</em> <!--><<!--> <!-->0.001, respectively). Compared to the preoperative period, there were significant increases in the postoperative anterior chamber angle (ACA) (38 [27–55]° vs. 52 [35–62]°, <em>P</em> <!--><<!--> <!-->0.001), anterior chamber depth (ACD) (2.67 [1.93–3.82] mm vs. 3.36 [2.7–4.25] mm, <em>P</em> <!--><<!--> <!-->0.001), and anterior chamber volume (ACV) (111 [87–208] mm<sup>3</sup> vs. 155 [110–252] mm<sup>3</sup>, <em>P</em> <!-->=<!--> <!-->0.001). No significant differences were detected in K1, K2, spherical equivalent (SE), best-corrected visual acuity (BCVA), or central corneal thickness (CCT) before and after GATT (<em>P</em> <!-->><!--> <!-->0.05).</div></div><div><h3>Conclusion</h3><div>In our study, a decrease in IOP and the NAGD used, as well as an increase in ACA, ACD, and ACV, were observed after GATT compared to the preoperative period. The lack of changes in K1, K2, SE, BCVA, and CCT suggests that the surgery may be advantageous in these aspects.</div></div><div><h3>Objectif</h3><div>Nous avons souhaité évaluer les paramètres du segment antérieur et les changements réfractifs après une trabéculectomie transluminale assistée par gonioscopie (GATT).</div></div><div><h3>Matériels et méthodes</h3><div>Cette étude rétrospective, transversale et observationnelle a inclus 21 yeux de 19 patients atteints de glaucome à angle ouvert ayant bénéficié d’un GATT d’au moins 180° entre février 2022 et janvier 2024. Les paramètres du segment antérieur, obtenus à l’aide dutopographe cornéen Sirius (CSO, Italie), ont été analysés rétrospectivement pour la période préopératoire et le troisième mois postopératoire.</div></div><div><h3>Résultats</h3><div>Parmi ces yeux, quatorze ont été diagnostiqués avec un glaucome primitif à angle ouvert, six avec un glaucome pseudoexfoliatif et un avec un glaucome pigmentaire. Comparativement à la période préopératoire, la pression intraoculaire (PIO) postopératoire et
目的:评价经腔镜辅助下小梁切开术(GATT)后前段参数和屈光变化。材料和方法:这项回顾性、横断面、观察性研究包括19例开角型青光眼患者的21只眼,这些患者在2022年2月至2024年1月期间接受了至少180°GATT手术。利用Sirius角膜地形图(CSO, Italy)获得的术前和术后第3个月的前段参数进行回顾性分析。结果:在研究人群中,14只眼被诊断为原发性开角型青光眼,6只眼被诊断为假剥脱性青光眼,1只眼被诊断为色素性青光眼。与术前相比,术后眼压(IOP)和抗青光眼药物(NAGD)使用数量明显降低(23 [15-35]mmHg vs. 14 [7-19] mmHg, P3 vs. 155 [110-252] mm3, P=0.001)。GATT前后的K1、K2、球形当量(SE)、最佳矫正视力(BCVA)、角膜中央厚度(CCT)均无显著差异(P < 0.05)。结论:在我们的研究中,与术前相比,GATT术后IOP和使用的NAGD下降,ACA、ACD和ACV增加。K1、K2、SE、BCVA和CCT没有变化,提示手术在这些方面可能是有利的。
{"title":"Anterior Segment Changes after Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) in Pseudophakic Patients with Open-angle Glaucoma","authors":"F.I. Sozen-Delil,&nbsp;R. Donmez Gun","doi":"10.1016/j.jfo.2025.104727","DOIUrl":"10.1016/j.jfo.2025.104727","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;We aimed to evaluate the anterior segment parameters and refractive changes after Gonioscopy-Assisted Transluminal Trabeculotomy (GATT).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Materials and methods&lt;/h3&gt;&lt;div&gt;This retrospective, cross-sectional, observational study included 21 eyes of 19 patients with open-angle glaucoma who underwent at least 180° GATT between February 2022 and January 2024. The anterior segment parameters obtained using Sirius corneal topography (CSO, Italy) were retrospectively reviewed for the preoperative period and the 3rd postoperative month.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Among the study population, fourteen eyes were diagnosed with primary open-angle glaucoma, six with pseudoexfoliative glaucoma, and one with pigmentary glaucoma. Compared to the preoperative period, the postoperative intraocular pressure (IOP) and the number of antiglaucomatous drugs (NAGD) used were significantly lower (23 [15–35] mmHg vs. 14 [7–19] mmHg, &lt;em&gt;P&lt;/em&gt; &lt;!--&gt;&lt;&lt;!--&gt; &lt;!--&gt;0.001; 4 [1–4] vs. 0 [0–3], &lt;em&gt;P&lt;/em&gt; &lt;!--&gt;&lt;&lt;!--&gt; &lt;!--&gt;0.001, respectively). Compared to the preoperative period, there were significant increases in the postoperative anterior chamber angle (ACA) (38 [27–55]° vs. 52 [35–62]°, &lt;em&gt;P&lt;/em&gt; &lt;!--&gt;&lt;&lt;!--&gt; &lt;!--&gt;0.001), anterior chamber depth (ACD) (2.67 [1.93–3.82] mm vs. 3.36 [2.7–4.25] mm, &lt;em&gt;P&lt;/em&gt; &lt;!--&gt;&lt;&lt;!--&gt; &lt;!--&gt;0.001), and anterior chamber volume (ACV) (111 [87–208] mm&lt;sup&gt;3&lt;/sup&gt; vs. 155 [110–252] mm&lt;sup&gt;3&lt;/sup&gt;, &lt;em&gt;P&lt;/em&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;0.001). No significant differences were detected in K1, K2, spherical equivalent (SE), best-corrected visual acuity (BCVA), or central corneal thickness (CCT) before and after GATT (&lt;em&gt;P&lt;/em&gt; &lt;!--&gt;&gt;&lt;!--&gt; &lt;!--&gt;0.05).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;In our study, a decrease in IOP and the NAGD used, as well as an increase in ACA, ACD, and ACV, were observed after GATT compared to the preoperative period. The lack of changes in K1, K2, SE, BCVA, and CCT suggests that the surgery may be advantageous in these aspects.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objectif&lt;/h3&gt;&lt;div&gt;Nous avons souhaité évaluer les paramètres du segment antérieur et les changements réfractifs après une trabéculectomie transluminale assistée par gonioscopie (GATT).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Matériels et méthodes&lt;/h3&gt;&lt;div&gt;Cette étude rétrospective, transversale et observationnelle a inclus 21 yeux de 19 patients atteints de glaucome à angle ouvert ayant bénéficié d’un GATT d’au moins 180° entre février 2022 et janvier 2024. Les paramètres du segment antérieur, obtenus à l’aide dutopographe cornéen Sirius (CSO, Italie), ont été analysés rétrospectivement pour la période préopératoire et le troisième mois postopératoire.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Résultats&lt;/h3&gt;&lt;div&gt;Parmi ces yeux, quatorze ont été diagnostiqués avec un glaucome primitif à angle ouvert, six avec un glaucome pseudoexfoliatif et un avec un glaucome pigmentaire. Comparativement à la période préopératoire, la pression intraoculaire (PIO) postopératoire et","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 1","pages":"Article 104727"},"PeriodicalIF":1.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145751897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of flap morphology and visual outcomes using a new femtosecond-laser platform: An observational study 利用飞秒激光平台分析皮瓣形态和视觉效果:一项观察性研究。
IF 1.1 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-12-12 DOI: 10.1016/j.jfo.2025.104716
S. Partouche , C. Panthier , A. Saad , D. Gatinel
<div><h3>Purpose</h3><div>To evaluate the accuracy in terms of thickness of LASIK flaps created using the ELITA<sup>TM</sup> femtosecond laser (Johnson and Johnson Surgical Vision, Inc) compared to the intended thickness.</div></div><div><h3>Methods</h3><div>This retrospective, single-center study was conducted at the Institut Noemie de Rothschild (Paris, France) in patients eligible for bilateral LASIK surgery. The ELITA<sup>TM</sup> femtosecond laser was used to create all flaps, with an intended thickness of 110<!--> <!-->μm or 120<!--> <!-->μm. Flap thickness was measured manually by using images from two Optical Coherence Tomography (OCT) devices: Anterion (Heidelberg Engineering), which uses a “Swept Source” technology, and Avanti (Optovue), which uses “Spectral Domain” technology. For each patient, two flap thickness measurements were obtained from the horizontal Anterion B-scan. Additionally, two Avanti scans, one horizontal and one vertical, were acquired per patient, with two flap thickness measurements recorded from each scan. Postoperative refractive and visual outcomes were also evaluated.</div></div><div><h3>Results</h3><div>30 eyes of 15 patients were included. 66.6% were female. The mean age of the patients was 31.4 years (range: 25 to 45 years). 48 Anterion measurements were obtained: mean flap thickness was 124.9<!--> <!-->±<!--> <!-->12.3<!--> <!-->μm (range 101 to 157<!--> <!-->μm). 120 Avanti measurements were obtained: mean flap thickness was 115.1<!--> <!-->±<!--> <!-->7.7<!--> <!-->μm (range 92 to 132<!--> <!-->μm). The mean deviations between the achieved and attempted flap thickness were 8.38<!--> <!-->±<!--> <!-->9<!--> <!-->μm by Anterion measurements and 6.67<!--> <!-->μm<!--> <!-->±<!--> <!-->4.72<!--> <!-->μm by Avanti measurements. The mean postoperative spherical equivalent was 0.05<!--> <!-->±<!--> <!-->0.43 diopters. The mean uncorrected visual acuity (UCVA) was 0.99 (LogMar). No intraoperative or postoperative complications occurred.</div></div><div><h3>Conclusion</h3><div>The ELITA femtosecond laser provides accurate and consistent LASIK flap thickness with excellent visual outcomes and no reported complications.</div></div><div><h3>Objectif</h3><div>Évaluer la précision de l’épaisseur des capots LASIK créés avec le laser femtoseconde ELITA<sup>TM</sup>(Johnson & Johnson Surgical Vision, Inc.) par rapport à l’épaisseur cible prévue.</div></div><div><h3>Méthodes</h3><div>Cette étude, rétrospective et monocentrique, a été menée à l’Institut Noémie de Rothschild (Paris, France) chez des patients éligibles à une chirurgie par LASIK bilatéral. Le laser femtoseconde ELITA<sup>TM</sup> a été utilisé pour créer tous les capots avec une épaisseur cible de 110<!--> <!-->μm ou de 120<!--> <!-->μm. L’épaisseur des capots a été mesurée en postopératoire à l’aide d’images provenant de deux dispositifs OCT : Anterion (Heidelberg Engineering) qui utilise une technologie « Swept-Source » et Avanti (Optovue) qui utilise une
目的:评估使用ELITATM飞秒激光(Johnson and Johnson Surgical Vision, Inc)制作的LASIK皮瓣厚度与预期厚度的准确性。方法:在法国巴黎Noemie de Rothschild研究所(Institut Noemie de Rothschild)对符合双侧LASIK手术条件的患者进行回顾性、单中心研究。使用ELITATM飞秒激光器制作所有皮瓣,其预期厚度为110μm或120μm。皮瓣厚度通过使用两个光学相干断层扫描(OCT)设备的图像进行手动测量:Anterion(海德堡工程公司)使用“扫描源”技术,Avanti (Optovue公司)使用“谱域”技术。对于每个患者,通过水平心房b扫描获得两个皮瓣厚度测量。此外,每位患者进行两次Avanti扫描,一次水平扫描,一次垂直扫描,每次扫描记录两次皮瓣厚度测量。术后屈光和视力结果也进行了评估。结果:纳入15例患者30只眼。66.6%为女性。患者平均年龄31.4岁(25 ~ 45岁)。48个心房测量值:皮瓣平均厚度为124.9±12.3μm(范围101 ~ 157μm)。获得120个Avanti测量值:皮瓣平均厚度为115.1±7.7μm(范围为92 ~ 132μm)。Anterion测得皮瓣厚度与尝试皮瓣厚度的平均偏差为8.38±9μm, Avanti测得皮瓣厚度的平均偏差为6.67±4.72μm。术后平均球面等效度为0.05±0.43屈光度。平均未矫正视力(UCVA)为0.99 (LogMar)。无术中、术后并发症发生。结论:ELITA飞秒激光提供准确一致的LASIK皮瓣厚度,视觉效果良好,无并发症报道。
{"title":"Analysis of flap morphology and visual outcomes using a new femtosecond-laser platform: An observational study","authors":"S. Partouche ,&nbsp;C. Panthier ,&nbsp;A. Saad ,&nbsp;D. Gatinel","doi":"10.1016/j.jfo.2025.104716","DOIUrl":"10.1016/j.jfo.2025.104716","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;To evaluate the accuracy in terms of thickness of LASIK flaps created using the ELITA&lt;sup&gt;TM&lt;/sup&gt; femtosecond laser (Johnson and Johnson Surgical Vision, Inc) compared to the intended thickness.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;This retrospective, single-center study was conducted at the Institut Noemie de Rothschild (Paris, France) in patients eligible for bilateral LASIK surgery. The ELITA&lt;sup&gt;TM&lt;/sup&gt; femtosecond laser was used to create all flaps, with an intended thickness of 110&lt;!--&gt; &lt;!--&gt;μm or 120&lt;!--&gt; &lt;!--&gt;μm. Flap thickness was measured manually by using images from two Optical Coherence Tomography (OCT) devices: Anterion (Heidelberg Engineering), which uses a “Swept Source” technology, and Avanti (Optovue), which uses “Spectral Domain” technology. For each patient, two flap thickness measurements were obtained from the horizontal Anterion B-scan. Additionally, two Avanti scans, one horizontal and one vertical, were acquired per patient, with two flap thickness measurements recorded from each scan. Postoperative refractive and visual outcomes were also evaluated.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;30 eyes of 15 patients were included. 66.6% were female. The mean age of the patients was 31.4 years (range: 25 to 45 years). 48 Anterion measurements were obtained: mean flap thickness was 124.9&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;12.3&lt;!--&gt; &lt;!--&gt;μm (range 101 to 157&lt;!--&gt; &lt;!--&gt;μm). 120 Avanti measurements were obtained: mean flap thickness was 115.1&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;7.7&lt;!--&gt; &lt;!--&gt;μm (range 92 to 132&lt;!--&gt; &lt;!--&gt;μm). The mean deviations between the achieved and attempted flap thickness were 8.38&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;9&lt;!--&gt; &lt;!--&gt;μm by Anterion measurements and 6.67&lt;!--&gt; &lt;!--&gt;μm&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;4.72&lt;!--&gt; &lt;!--&gt;μm by Avanti measurements. The mean postoperative spherical equivalent was 0.05&lt;!--&gt; &lt;!--&gt;±&lt;!--&gt; &lt;!--&gt;0.43 diopters. The mean uncorrected visual acuity (UCVA) was 0.99 (LogMar). No intraoperative or postoperative complications occurred.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;The ELITA femtosecond laser provides accurate and consistent LASIK flap thickness with excellent visual outcomes and no reported complications.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objectif&lt;/h3&gt;&lt;div&gt;Évaluer la précision de l’épaisseur des capots LASIK créés avec le laser femtoseconde ELITA&lt;sup&gt;TM&lt;/sup&gt;(Johnson &amp; Johnson Surgical Vision, Inc.) par rapport à l’épaisseur cible prévue.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Méthodes&lt;/h3&gt;&lt;div&gt;Cette étude, rétrospective et monocentrique, a été menée à l’Institut Noémie de Rothschild (Paris, France) chez des patients éligibles à une chirurgie par LASIK bilatéral. Le laser femtoseconde ELITA&lt;sup&gt;TM&lt;/sup&gt; a été utilisé pour créer tous les capots avec une épaisseur cible de 110&lt;!--&gt; &lt;!--&gt;μm ou de 120&lt;!--&gt; &lt;!--&gt;μm. L’épaisseur des capots a été mesurée en postopératoire à l’aide d’images provenant de deux dispositifs OCT : Anterion (Heidelberg Engineering) qui utilise une technologie « Swept-Source » et Avanti (Optovue) qui utilise une","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 1","pages":"Article 104716"},"PeriodicalIF":1.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145751859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance of new Corvis ST parameters in differentiating between healthy corneas and different stages of keratoconus in a North African population 新Corvis ST参数在北非人群中区分健康角膜和不同阶段圆锥角膜的性能
IF 1.1 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-12-12 DOI: 10.1016/j.jfo.2025.104719
B. Omari , C. Khodriss , C. El Ouazzani , F. Bousgheiri , S. Lemrabett , M. El Bahloul
<div><h3>Purpose</h3><div>To determine the accuracy of various biomechanical parameters, including the updated version of the stress–strain index (SSIv2), the Corvis Biomechanical Factor (CBiF), and the Chinese Corvis Biomechanical Index (cCBI), in differentiating between normal corneas and keratoconus at different stages in a North African population.</div></div><div><h3>Methods</h3><div>This prospective observational case-control study included three groups: the normal group (100 eyes), moderate keratoconus group (KC grade 1: 56 eyes), and severe keratoconus group (KC Grade 2: 51 eyes). Each eye underwent Corvis ST examination to determine the stiffness parameter at first applanation (SP-A1), Ambrósio relational thickness (ARTh), integrated inverse radius (IIR), velocity at first applanation (velocity A1), biomechanical-corrected IOP (bIOP), tomographic and biomechanical index (TBI), CBI, and the new parameters SSIv2, CBiF, and cCBI. Comparison of biomechanical parameters between groups was performed using ANOVA or Kruskal-Wallis tests (with <em>P</em> <!--><<!--> <!-->0.05). The performance of these parameters was evaluated using ROC (Receiver Operating Characteristic) curves by determining AUCs (Area Under the Curve), which were compared using DeLong's test.</div></div><div><h3>Results</h3><div>Before and after correction for age, central corneal thickness, and bIOP, most biomechanical parameters were significantly different among the three groups (<em>P</em> <!--><<!--> <!-->0.05). The TBI had the highest diagnostic accuracy (AUC<!--> <!-->=<!--> <!-->0.997) in detecting keratoconus, followed by the CBI (0.975), ARTh (0.948), and IIR (0.939). The CBI and ARTh presented the highest efficacy in differentiating between keratoconus severities (AUC<!--> <!-->=<!--> <!-->0.861 and 0.850, respectively). CBiF and cCBI showed excellent ability to diagnose keratoconus (AUC<!--> <!-->=<!--> <!-->0.937 and 0.933, respectively). SSIv2 demonstrated good potential (AUC<!--> <!-->=<!--> <!-->0.796) for detecting keratoconus.</div></div><div><h3>Conclusion</h3><div>In a North African population, the TBI best distinguished keratoconus eyes from normal eyes, followed by the CBI and ARTh. CBiF, cCBI, and SSIv2 demonstrated excellent performance, albeit less so.</div></div><div><h3>Objectif</h3><div>Déterminer la performance des paramètres biomécaniques, incluant la version optimisée de l’indice Stress-Strain (SSIv2), le Corvis Biomechanical Factor (CBiF) et le Chinese Corvis Biomechanical Index (cCBI), pour différencier, au sein d’une population nord-africaine, les cornées normales des kératocônes de différents stades.</div></div><div><h3>Matériels et méthodes</h3><div>Il s’agit d’une étude observationnelle prospective type cas-témoins incluant trois groupes : le groupe normal (100 yeux), le groupe kératocône modéré (KC grade 1 : 56 yeux) et le groupe kératocône sévère (KC grade 2 : 51 yeux). Chaque œil a bénéficié d’une imagerie par Corvis ST pour déterm
目的:确定各种生物力学参数的准确性,包括应力-应变指数(SSIv2)、Corvis生物力学因子(cif)和中国Corvis生物力学指数(cCBI),以区分北非人群不同阶段的正常角膜和圆锥角膜。方法:本前瞻性观察性病例对照研究分为正常组(100眼)、中度圆锥角膜组(KC分级1级:56眼)、重度圆锥角膜组(KC分级2级:51眼)三组。每只眼进行Corvis ST检查,以确定首次压平时的刚度参数(SP-A1)、Ambrósio相关厚度(ARTh)、积分反半径(IIR)、首次压平时的速度(velocity A1)、生物力学校正IOP (bIOP)、断层扫描和生物力学指数(TBI)、CBI以及新参数SSIv2、cif和cCBI。采用方差分析(ANOVA)或Kruskal-Wallis检验比较各组间的生物力学参数(结果:在年龄、角膜中央厚度和bIOP校正前后,三组间的大多数生物力学参数存在显著差异)。结论:在北非人群中,TBI最能将圆锥角膜与正常眼睛区分出来,其次是CBI和ARTh。cif、cCBI和SSIv2表现出了出色的性能,尽管不那么出色。
{"title":"Performance of new Corvis ST parameters in differentiating between healthy corneas and different stages of keratoconus in a North African population","authors":"B. Omari ,&nbsp;C. Khodriss ,&nbsp;C. El Ouazzani ,&nbsp;F. Bousgheiri ,&nbsp;S. Lemrabett ,&nbsp;M. El Bahloul","doi":"10.1016/j.jfo.2025.104719","DOIUrl":"10.1016/j.jfo.2025.104719","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;To determine the accuracy of various biomechanical parameters, including the updated version of the stress–strain index (SSIv2), the Corvis Biomechanical Factor (CBiF), and the Chinese Corvis Biomechanical Index (cCBI), in differentiating between normal corneas and keratoconus at different stages in a North African population.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;This prospective observational case-control study included three groups: the normal group (100 eyes), moderate keratoconus group (KC grade 1: 56 eyes), and severe keratoconus group (KC Grade 2: 51 eyes). Each eye underwent Corvis ST examination to determine the stiffness parameter at first applanation (SP-A1), Ambrósio relational thickness (ARTh), integrated inverse radius (IIR), velocity at first applanation (velocity A1), biomechanical-corrected IOP (bIOP), tomographic and biomechanical index (TBI), CBI, and the new parameters SSIv2, CBiF, and cCBI. Comparison of biomechanical parameters between groups was performed using ANOVA or Kruskal-Wallis tests (with &lt;em&gt;P&lt;/em&gt; &lt;!--&gt;&lt;&lt;!--&gt; &lt;!--&gt;0.05). The performance of these parameters was evaluated using ROC (Receiver Operating Characteristic) curves by determining AUCs (Area Under the Curve), which were compared using DeLong's test.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Before and after correction for age, central corneal thickness, and bIOP, most biomechanical parameters were significantly different among the three groups (&lt;em&gt;P&lt;/em&gt; &lt;!--&gt;&lt;&lt;!--&gt; &lt;!--&gt;0.05). The TBI had the highest diagnostic accuracy (AUC&lt;!--&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;0.997) in detecting keratoconus, followed by the CBI (0.975), ARTh (0.948), and IIR (0.939). The CBI and ARTh presented the highest efficacy in differentiating between keratoconus severities (AUC&lt;!--&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;0.861 and 0.850, respectively). CBiF and cCBI showed excellent ability to diagnose keratoconus (AUC&lt;!--&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;0.937 and 0.933, respectively). SSIv2 demonstrated good potential (AUC&lt;!--&gt; &lt;!--&gt;=&lt;!--&gt; &lt;!--&gt;0.796) for detecting keratoconus.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;In a North African population, the TBI best distinguished keratoconus eyes from normal eyes, followed by the CBI and ARTh. CBiF, cCBI, and SSIv2 demonstrated excellent performance, albeit less so.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Objectif&lt;/h3&gt;&lt;div&gt;Déterminer la performance des paramètres biomécaniques, incluant la version optimisée de l’indice Stress-Strain (SSIv2), le Corvis Biomechanical Factor (CBiF) et le Chinese Corvis Biomechanical Index (cCBI), pour différencier, au sein d’une population nord-africaine, les cornées normales des kératocônes de différents stades.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Matériels et méthodes&lt;/h3&gt;&lt;div&gt;Il s’agit d’une étude observationnelle prospective type cas-témoins incluant trois groupes : le groupe normal (100 yeux), le groupe kératocône modéré (KC grade 1 : 56 yeux) et le groupe kératocône sévère (KC grade 2 : 51 yeux). Chaque œil a bénéficié d’une imagerie par Corvis ST pour déterm","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 1","pages":"Article 104719"},"PeriodicalIF":1.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145751872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Descemet membrane endothelial keratoplasty in patients with anterior chamber iris-claw lenses: Clinical outcomes and recommendations 前房虹膜-爪状晶状体患者的内皮角膜移植术:临床结果和建议。
IF 1.1 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-12-12 DOI: 10.1016/j.jfo.2025.104730
E. Fernández López, C. Martínez Gil, E. Arias García, M. Bautista Cortiella, G. Roig Ferreruela
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引用次数: 0
Complete involution of retinal hemangioblastoma with single session cryotherapy 单次冷冻治疗视网膜血管母细胞瘤完全消退。
IF 1.1 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-12-23 DOI: 10.1016/j.jfo.2025.104744
A.M. Ahmed, R.A. Choudhury, C.L. Shields
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引用次数: 0
Sommaire 摘要
IF 1.1 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2026-01-30 DOI: 10.1016/S0181-5512(25)00347-X
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引用次数: 0
Evaluating the quality of cataract clinical practice guidelines: A systematic review using the AGREE II instrument 评价白内障临床实践指南的质量:使用AGREE II工具的系统评价
IF 1.1 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-12-08 DOI: 10.1016/j.jfo.2025.104710
M. Sanguino-Jaramillo , A. Domínguez-Vargas , J. Galeano-Lopez , G. Cadavía-Carrascal
<div><h3>Introduction</h3><div>Clinical practice guidelines (CPGs) are crucial for providing evidence-based recommendations to improve patient care. Over the past 30 years, CPG development has progressed, particularly in addressing variations in care. However, significant disparities remain, especially in low- and middle-income countries. This systematic review aims to evaluate the methodological quality of cataract-related CPGs published between 2000 and 2023 by using the AGREE II instrument.</div></div><div><h3>Methods</h3><div>A comprehensive search identified 11 CPGs meeting eligibility criteria, assessed across six domains: Scope and Purpose, Stakeholder Involvement, Rigor of Development, Clarity of Presentation, Applicability, and Editorial Independence.</div></div><div><h3>Results</h3><div>CPGs from the United States, National Institute for Health and Care Excellence (NICE), and Peru showed high scores in Rigor of Development and Scope and Purpose domains. Conversely, guidelines from Asia, Chile, and Mexico were not recommended due to deficiencies across multiple domains. Applicability emerged as the weakest domain across all CPGs, indicating challenges in translating guidelines into practice.</div></div><div><h3>Conclusions</h3><div>These findings highlight variability in CPG quality, emphasizing the need for ongoing improvements, particularly in Stakeholder Involvement and Applicability domains. Continued efforts to enhance methodological rigor and practical applicability are crucial for improving quality of care in cataract management.</div></div><div><h3>Introduction</h3><div>Les lignes directrices de pratique clinique (LPC) sont essentielles pour fournir des recommandations basées sur des preuves afin d’améliorer les soins aux patients. Au cours des 30 dernières années, le développement des LPC a progressé, notamment pour répondre aux variations dans les soins. Cependant, des disparités significatives persistent, en particulier dans les pays à revenus faible et intermédiaire. Cette revue systématique visait à évaluer la qualité méthodologique des LPC liées à la cataracte et publiées entre 2000 et 2023 en utilisant l’instrument AGREE II.</div></div><div><h3>Méthodes</h3><div>Une recherche exhaustive a identifié 11 LPC répondant aux critères d’éligibilité, évaluées dans six domaines : Portée et Objectifs, Implication des Parties Prenantes, Rigueur du Développement, Clarté de la Présentation, Applicabilité et Indépendance Éditoriale.</div></div><div><h3>Résultats</h3><div>Les LPC des États-Unis, du National Institute for Health and Care Excellence (NICE) et du Pérou ont obtenu des scores élevés dans les domaines Rigueur du Développement et Portée et Objectifs. En revanche, les lignes directrices d’Asie, du Chili et du Mexique n’ont pas été recommandées en raison de lacunes dans plusieurs domaines. L’applicabilité s’est révélée être le domaine le plus faible pour toutes les LPC, indiquant des défis dans la traduction des lignes directrice
临床实践指南(cpg)对于提供循证建议以改善患者护理至关重要。在过去的30年里,CPG的发展取得了进展,特别是在解决护理差异方面。然而,差距仍然很大,特别是在低收入和中等收入国家。本系统综述旨在通过使用AGREE II仪器评估2000年至2023年间发表的白内障相关cpg的方法学质量。方法通过全面搜索确定了11个符合资格标准的cpg,并在六个领域进行了评估:范围和目的、利益相关者参与、开发的严密性、表述的清晰度、适用性和编辑独立性。结果来自美国、国家卫生与保健卓越研究所(NICE)和秘鲁的scpg在发展严谨性和范围与目的领域得分较高。相反,亚洲、智利和墨西哥的指南由于多个领域的不足而不被推荐。适用性是所有CPGs中最薄弱的领域,这表明将指南转化为实践存在挑战。这些发现突出了CPG质量的可变性,强调了持续改进的必要性,特别是在利益相关者参与和适用性领域。不断努力提高方法的严谨性和实际适用性是提高白内障治疗质量的关键。简介:《临床实践指南》(LPC)提出了四项基本建议,即在患者的治疗过程中,对患者的治疗方法进行了改进。在课程中,30种不同的 交换器和其他交换器的交换器和其他交换器的交换器的交换器。在此之前,差别的薪金具有重要的持久性,特别是在薪金和薪金之间的差别。在2000年和2023年的《实用工具协议II》中,将系统的薪金薪金与签证薪金、薪金薪金、薪金薪金、薪金薪金、薪金薪金、薪金薪金、薪金薪金、薪金薪金、薪金薪金、薪金薪金和薪金薪金进行比较。该研究详尽地确定了11个LPC的交换交换和交换交换条件:交换交换和交换交换条件、交换交换条件、交换交换条件、交换交换条件、交换交换条件、交换交换条件、交换交换条件、交换交换条件和交换交换条件。ResultatsLes LPC的des美国杜国家健康和保健研究所(NICE)等杜Perou位于安大略省obtenu des分数eleves在下属分支的du开发署等矿物等目的。在复仇、亚洲、智利、墨西哥和其他地区,我们都建议在不同的领域采用不同的标准。L ' applicabilit ' s 'est rs - cys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys - sys。结论:变异体与变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体、变异体。“努力的过程”和“适用的过程”和“关键的过程”都是指“成功的过程”和“成功的过程”,即“成功的过程”和“成功的过程”。
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引用次数: 0
Anterior segment optical coherence tomography of silicone oil conjunctivopathy 硅油结膜病前段光学相干断层扫描。
IF 1.1 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-12-12 DOI: 10.1016/j.jfo.2025.104715
M.U. Mustafa, A. Zafar, C.L. Shields
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引用次数: 0
Herpetic dendritic ulcer resistant to valaciclovir successfully treated with amenamevir 阿莫那韦成功治疗了对伐昔洛韦耐药的疱疹树突状溃疡。
IF 1.1 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2026-01-01 Epub Date: 2025-12-12 DOI: 10.1016/j.jfo.2025.104728
R. Attia , V. Reynaud , R. Fitoussi , T. David
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Journal Francais D Ophtalmologie
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