Pub Date : 2017-08-18DOI: 10.15406/JNMR.2017.06.00145
L. Mezentseva, Alex, R. Osipov, V. Ugolkov, A. Akatov, V. Doil’nitsyn, T. Maslennikova, Aleks, R. Yakovlev
technique with inverse precipitation and further dehydrated upon high heating rate to retain nanoscale. From this point of view the aim of this study was to investigate peculiarities of formation of nanopowders in the systems where components belong to the same or different structural groups, to determine their isomorphic capacity, to study thermal behavior, and thereby to develop physical and chemical approaches to prepare ceramic samples (as matrices) based on them. In this case the second component plays a role of immobilized ion (isotope).
{"title":"Synthesis and Thermal Behavior of Nanopowders in LaPO4-YPO4(-H2O), LaPO4-LuPO4(-H2O) and YPO4-ScPO4(-H2O) Systems for Ceramic Matrices","authors":"L. Mezentseva, Alex, R. Osipov, V. Ugolkov, A. Akatov, V. Doil’nitsyn, T. Maslennikova, Aleks, R. Yakovlev","doi":"10.15406/JNMR.2017.06.00145","DOIUrl":"https://doi.org/10.15406/JNMR.2017.06.00145","url":null,"abstract":"technique with inverse precipitation and further dehydrated upon high heating rate to retain nanoscale. From this point of view the aim of this study was to investigate peculiarities of formation of nanopowders in the systems where components belong to the same or different structural groups, to determine their isomorphic capacity, to study thermal behavior, and thereby to develop physical and chemical approaches to prepare ceramic samples (as matrices) based on them. In this case the second component plays a role of immobilized ion (isotope).","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":"14 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2017-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86326267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-15DOI: 10.15406/JNMR.2017.06.00144
Sachin Somwanshi, V. Kunde, R. Dolas
{"title":"The Pitfalls of Growing Nanomedicine in Relation to the Specific Nanoscale Properties: Mini Review","authors":"Sachin Somwanshi, V. Kunde, R. Dolas","doi":"10.15406/JNMR.2017.06.00144","DOIUrl":"https://doi.org/10.15406/JNMR.2017.06.00144","url":null,"abstract":"","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":"45 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85567840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-11DOI: 10.15406/JNMR.2017.06.00143
G. ArumugamDhanesh, Hi, Dh, apani Kayal Vizhi, K. Lavanya, R. Babujanarthanam
Microorganism secret high molecular weight compound called as extra cellular polymeric substance (EPS) which is attached on the outer surface of the bacteria which is mostly release during its log phase. Bacterial EPS have been identified as one of the major components in biofilms [1]. Biofilms are formed with interaction among microbial aggregates, filamentous bacterial strains, organic and inorganic particles, which are held together by EPS [2]. The biofilms are complex structure where microbial cell aggregates are embedded inside a hydrated matrix made up of extra cellular polymeric substances. EPS majorly comprised of four substance called carbohydrate, protein, lipids and environmental DNA (e DNA). This biofilm acts as a protective barrier and provides resistance against antibiotics, degrading enzymes, protozoan grazers and host immune response [3].
{"title":"Modification in Extra Cellular Polymeric Substances of Staphylococcus aureus Using Sesbania grandiflora","authors":"G. ArumugamDhanesh, Hi, Dh, apani Kayal Vizhi, K. Lavanya, R. Babujanarthanam","doi":"10.15406/JNMR.2017.06.00143","DOIUrl":"https://doi.org/10.15406/JNMR.2017.06.00143","url":null,"abstract":"Microorganism secret high molecular weight compound called as extra cellular polymeric substance (EPS) which is attached on the outer surface of the bacteria which is mostly release during its log phase. Bacterial EPS have been identified as one of the major components in biofilms [1]. Biofilms are formed with interaction among microbial aggregates, filamentous bacterial strains, organic and inorganic particles, which are held together by EPS [2]. The biofilms are complex structure where microbial cell aggregates are embedded inside a hydrated matrix made up of extra cellular polymeric substances. EPS majorly comprised of four substance called carbohydrate, protein, lipids and environmental DNA (e DNA). This biofilm acts as a protective barrier and provides resistance against antibiotics, degrading enzymes, protozoan grazers and host immune response [3].","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":"84 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2017-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83547866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-08DOI: 10.15406/JNMR.2017.06.00142
Dercas Caneus
In the realm of nanotechnology, there are no barriers aside from a researcher’s imagination that can prevent the field from being a reputable force. The emergence of nanomedicine is an actual benefit in the increased interest placed within the food sector. As the field evolves, it is in a constant state of improvement. Researchers seek for innovative ways to combine the fundamentals of Nano-measurement with the emerging importance of colon health. Nanotechnology is becoming a valuable source of supportive help to the once known golden standards of gastroenterology. The once preventative measures used for colon carcinomas, ulcerative colitis, and Celiac Disease and an option for post treatment bacterial and viral enteritis, has gotten the sense of melioration in the technology. There is an importance in understanding the microbial flora of the gut, and the efforts to maintain it and with promising results; nanotechnology is becoming increasingly important for the food sector.
{"title":"Nanotechnology and its Partnership with Synbiotics","authors":"Dercas Caneus","doi":"10.15406/JNMR.2017.06.00142","DOIUrl":"https://doi.org/10.15406/JNMR.2017.06.00142","url":null,"abstract":"In the realm of nanotechnology, there are no barriers aside from a researcher’s imagination that can prevent the field from being a reputable force. The emergence of nanomedicine is an actual benefit in the increased interest placed within the food sector. As the field evolves, it is in a constant state of improvement. Researchers seek for innovative ways to combine the fundamentals of Nano-measurement with the emerging importance of colon health. Nanotechnology is becoming a valuable source of supportive help to the once known golden standards of gastroenterology. The once preventative measures used for colon carcinomas, ulcerative colitis, and Celiac Disease and an option for post treatment bacterial and viral enteritis, has gotten the sense of melioration in the technology. There is an importance in understanding the microbial flora of the gut, and the efforts to maintain it and with promising results; nanotechnology is becoming increasingly important for the food sector.","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88499839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-04DOI: 10.15406/JNMR.2017.06.00141
Jingyu Wang, S. Chowdhury, De-Cheng Wu, B. Bohnstedt, Yingtao Liu, Chung-Hao Lee
This paper presented the synthesis and characterization of carbon nanotubes (CNTs) enhanced aliphatic urethane shape memory polymer (SMP) nanocomposites for the development of biomedical devices. Critical polymer properties, such as the glass transition temperature and shape memory function, have been tailored to desired applications, by adjusting the polymer composition. CNTs were uniformly dispersed within the polymer during nanocomposite fabrication. The synthesized SMPs nanocomposites were characterized to understand their thermal and mechanical properties. Novel biomedical devices for intracranial aneurysm treatment will be developed using these SMPs.
{"title":"Carbon Nanotube Enhanced Shape Memory Polymer Nanocomposites for Development of Biomedical Devices","authors":"Jingyu Wang, S. Chowdhury, De-Cheng Wu, B. Bohnstedt, Yingtao Liu, Chung-Hao Lee","doi":"10.15406/JNMR.2017.06.00141","DOIUrl":"https://doi.org/10.15406/JNMR.2017.06.00141","url":null,"abstract":"This paper presented the synthesis and characterization of carbon nanotubes (CNTs) enhanced aliphatic urethane shape memory polymer (SMP) nanocomposites for the development of biomedical devices. Critical polymer properties, such as the glass transition temperature and shape memory function, have been tailored to desired applications, by adjusting the polymer composition. CNTs were uniformly dispersed within the polymer during nanocomposite fabrication. The synthesized SMPs nanocomposites were characterized to understand their thermal and mechanical properties. Novel biomedical devices for intracranial aneurysm treatment will be developed using these SMPs.","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":"34 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83080386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-01DOI: 10.15406/JNMR.2017.05.00140
Suman Pahal, R. Gakhar, A. Raichur, M. Varma
Highly tuneable architecture of PEMs with nanometres precision is the most promising aspect to utilize them for variety of applications. The bulk loading properties of polyelectrolyte multilayer thin films (PEM) motivate researchers to utilize them as a carrier for biomedical applications. For designing an efficient carrier polymeric assembly for targeted and controlled drug delivery, it is very important to understand the loading and release kinetics of bio-molecules across PEM matrix. Therefore, a better and complete understanding of the molecular diffusion is highly recommended to achieve success in these areas. This mini review provides an overview of the current efforts in understanding the bio-molecular transport across the polymer thin films. Different strategies involving confocal-based approaches along with recent innovative techniques have been briefly explained here to probe biomolecules in PEM. Pros and cons of each technique with future perspectives are discussed to render the most suitable technique for understanding the permeability of desired polymer matrix.
{"title":"Probing Bio-Molecules across Polyelectrolyte Multilayers","authors":"Suman Pahal, R. Gakhar, A. Raichur, M. Varma","doi":"10.15406/JNMR.2017.05.00140","DOIUrl":"https://doi.org/10.15406/JNMR.2017.05.00140","url":null,"abstract":"Highly tuneable architecture of PEMs with nanometres precision is the most promising aspect to utilize them for variety of applications. The bulk loading properties of polyelectrolyte multilayer thin films (PEM) motivate researchers to utilize them as a carrier for biomedical applications. For designing an efficient carrier polymeric assembly for targeted and controlled drug delivery, it is very important to understand the loading and release kinetics of bio-molecules across PEM matrix. Therefore, a better and complete understanding of the molecular diffusion is highly recommended to achieve success in these areas. This mini review provides an overview of the current efforts in understanding the bio-molecular transport across the polymer thin films. Different strategies involving confocal-based approaches along with recent innovative techniques have been briefly explained here to probe biomolecules in PEM. Pros and cons of each technique with future perspectives are discussed to render the most suitable technique for understanding the permeability of desired polymer matrix.","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72738563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-21DOI: 10.15406/JNMR.2017.05.00138
D. Hariharan, K. Srinivasan, L. Nehru
The nano particles are different from the large particles of the same composition because of their large surface area and volume ratio. The metal oxide nanoparticles have received considerable attention on medical line due to their antibacterial properties, resistance against microbes, drug delivery, antibiotics and immune chromatography, tissue / tumour image, anticancer activities and identification of pathogens in clinical specimens [1-2]. TiO2 is the most promising material in the group of the metal oxides. In n type semiconductor, titanium dioxide is a most important semiconductor due to its light absorption, surface adsorption and charge transport properties [3]. TiO2 has three crystal structures namely anatase, rutile, and brookite. In three phases, the anatase phase has got applications in photo-voltaic cells (Fujima and Donald 2000), photo catalysts and more applications for its antimicrobial properties [4].
纳米颗粒具有较大的表面积和体积比，不同于相同成分的大颗粒。金属氧化物纳米颗粒由于其抗菌特性、抗微生物、药物传递、抗生素和免疫层析、组织/肿瘤图像、抗癌活性和临床标本中病原体的鉴定而受到医学界的广泛关注[1-2]。TiO2是金属氧化物中最有前途的材料。在n型半导体中，二氧化钛因其光吸收、表面吸附和电荷输运等特性而成为最重要的半导体材料。TiO2具有锐钛矿、金红石、蓝铜矿三种晶体结构。在三个阶段中，锐钛矿相因其抗菌性能在光伏电池(Fujima and Donald 2000)、光催化剂以及更多的应用中得到了应用。
{"title":"Synthesis and Characterization of Tio2 Nanoparticles Using Cynodon Dactylon Leaf Extract for Antibacterial and Anticancer (A549 Cell Lines) Activity","authors":"D. Hariharan, K. Srinivasan, L. Nehru","doi":"10.15406/JNMR.2017.05.00138","DOIUrl":"https://doi.org/10.15406/JNMR.2017.05.00138","url":null,"abstract":"The nano particles are different from the large particles of the same composition because of their large surface area and volume ratio. The metal oxide nanoparticles have received considerable attention on medical line due to their antibacterial properties, resistance against microbes, drug delivery, antibiotics and immune chromatography, tissue / tumour image, anticancer activities and identification of pathogens in clinical specimens [1-2]. TiO2 is the most promising material in the group of the metal oxides. In n type semiconductor, titanium dioxide is a most important semiconductor due to its light absorption, surface adsorption and charge transport properties [3]. TiO2 has three crystal structures namely anatase, rutile, and brookite. In three phases, the anatase phase has got applications in photo-voltaic cells (Fujima and Donald 2000), photo catalysts and more applications for its antimicrobial properties [4].","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":"115 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79365875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-13DOI: 10.15406/JNMR.2017.05.00137
S. Mukherjee, R. Shunmugam
Self-assembly of amphiphilic polymer opens a new avenue in the biomedical field; particularly, amphiphilic polymer vesicles have generally shown promising potential in drug delivery applications. The advantage of nanoparticle for drug delivery is because of the direct injection of these kind molecules to the body which will circulate in the body without any coagulation or blocking. The amphiphilic nature makes the micelles an effective carrier for the drugs, which are struggling with poor solubility, limited stability, and toxicity.
{"title":"Polymer based Nano-Assemblies: Very Efficient Carrier in the Field of Cancer Chemotherapy","authors":"S. Mukherjee, R. Shunmugam","doi":"10.15406/JNMR.2017.05.00137","DOIUrl":"https://doi.org/10.15406/JNMR.2017.05.00137","url":null,"abstract":"Self-assembly of amphiphilic polymer opens a new avenue in the biomedical field; particularly, amphiphilic polymer vesicles have generally shown promising potential in drug delivery applications. The advantage of nanoparticle for drug delivery is because of the direct injection of these kind molecules to the body which will circulate in the body without any coagulation or blocking. The amphiphilic nature makes the micelles an effective carrier for the drugs, which are struggling with poor solubility, limited stability, and toxicity.","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79725763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-12DOI: 10.15406/JNMR.2017.05.00136
K. Santhoshkumar, Monami Das Modak, P. Paik
Graphene oxide (GO) is one of the most promising functional materials used in various applications like energy storage (batteries and supercapacitors) sensors, photocatalysis, electronics and in biomedicine. The last 10 years literature on GO for biomedical applications revealed and confirmed the scope of its potential capabilities as biomaterial. GO alone and its modified form with different materials (surface functionalization, immobilization of nanoparticles and composite formation) also proved as a multifunctional candidate for medical biotechnology. A material for its use in biomedical applications must be biocompatible and nontoxic to the living cells.. Although there are some concerns about the toxicity of the GO in specific cases, a dosage range and size effects reported in the literature to use it as a nontoxic materials. In view of all these points, an effort has been made to review and emphasize the scope of GO as a biomedical agent for the applications like targeted drug delivery, cancer theranostics, bioimaging and biosensors etc. Further, potential applications along with the future scope and limitations of GO have also been highlighted in this review.
{"title":"Graphene Oxide for Biomedical Applications","authors":"K. Santhoshkumar, Monami Das Modak, P. Paik","doi":"10.15406/JNMR.2017.05.00136","DOIUrl":"https://doi.org/10.15406/JNMR.2017.05.00136","url":null,"abstract":"Graphene oxide (GO) is one of the most promising functional materials used in various applications like energy storage (batteries and supercapacitors) sensors, photocatalysis, electronics and in biomedicine. The last 10 years literature on GO for biomedical applications revealed and confirmed the scope of its potential capabilities as biomaterial. GO alone and its modified form with different materials (surface functionalization, immobilization of nanoparticles and composite formation) also proved as a multifunctional candidate for medical biotechnology. A material for its use in biomedical applications must be biocompatible and nontoxic to the living cells.. Although there are some concerns about the toxicity of the GO in specific cases, a dosage range and size effects reported in the literature to use it as a nontoxic materials. In view of all these points, an effort has been made to review and emphasize the scope of GO as a biomedical agent for the applications like targeted drug delivery, cancer theranostics, bioimaging and biosensors etc. Further, potential applications along with the future scope and limitations of GO have also been highlighted in this review.","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89853366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-12DOI: 10.15406/JNMR.2017.05.00135
Jianming Li
The foreign body reaction describes the host’s inflammatory response to an exogenous material. In the rapidly expanding disciplines of nanotechnology and nanomedicine, the interplay between an implant and host tissue has become increasingly important. Nanomedicine fundamentally aims to monitor and direct cell function at the molecular length scale. Controlling cell-biomaterial interactions is key to successful therapeutic implementation. However, current in vitro practice does not adequately address the foreign body reaction. In this opinion, I summarize consequences of the foreign body inflammatory response and its implications in nanoscale therapeutic designs.
{"title":"Biomaterial and Cell Interactions - The Foreign Body Response as an Obstacle in Nanomedicine","authors":"Jianming Li","doi":"10.15406/JNMR.2017.05.00135","DOIUrl":"https://doi.org/10.15406/JNMR.2017.05.00135","url":null,"abstract":"The foreign body reaction describes the host’s inflammatory response to an exogenous material. In the rapidly expanding disciplines of nanotechnology and nanomedicine, the interplay between an implant and host tissue has become increasingly important. Nanomedicine fundamentally aims to monitor and direct cell function at the molecular length scale. Controlling cell-biomaterial interactions is key to successful therapeutic implementation. However, current in vitro practice does not adequately address the foreign body reaction. In this opinion, I summarize consequences of the foreign body inflammatory response and its implications in nanoscale therapeutic designs.","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86517055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：