Ali Anil Demircali, Abdurrahim Yilmaz, Huseyin Uvet
The efficient mixing of fluids at microscale dimensions presents challenges due to the dominant laminar flow regime which restricts convective mixing. This study introduces a numerical analysis of a novel microrobotic mixing system with a levitated propeller robot, driven by magnetic fields, within a Y-shaped microchannel with a square cross-section (500 × 500 μm). Our research investigates the fluid mixing effectiveness facilitated by the microrobot through various levitation heights and orientations to enhance the mixing index (MI). This index is tested under different conditions by leveraging the dynamics of the propeller robot, characterized by adjustable roll and pitch angles and varying levitation heights. The numerical simulations, conducted using COMSOL® (Finite Element Method, FEM) software, integrate Maxwell's equations for magnetic field interaction with momentum and transport-diffusion equations to analyze fluid dynamics within the microchannel. Results indicate that the propeller robot can achieve an MI of up to 98.94% at a 150 μm levitation height and 1500 rpm propeller speed within 3 s. Additionally, the study examines the impact of propeller speed, Reynolds number, and robot length on mixing performance, providing comprehensive guidance for optimizing microscale fluid mixing in lab-on-a-chip applications.
{"title":"Enhanced Fluid Mixing in Microchannels Using Levitated Magnetic Microrobots: A Numerical Study.","authors":"Ali Anil Demircali, Abdurrahim Yilmaz, Huseyin Uvet","doi":"10.3390/mi16010052","DOIUrl":"10.3390/mi16010052","url":null,"abstract":"<p><p>The efficient mixing of fluids at microscale dimensions presents challenges due to the dominant laminar flow regime which restricts convective mixing. This study introduces a numerical analysis of a novel microrobotic mixing system with a levitated propeller robot, driven by magnetic fields, within a Y-shaped microchannel with a square cross-section (500 × 500 μm). Our research investigates the fluid mixing effectiveness facilitated by the microrobot through various levitation heights and orientations to enhance the mixing index (MI). This index is tested under different conditions by leveraging the dynamics of the propeller robot, characterized by adjustable roll and pitch angles and varying levitation heights. The numerical simulations, conducted using COMSOL<sup>®</sup> (Finite Element Method, FEM) software, integrate Maxwell's equations for magnetic field interaction with momentum and transport-diffusion equations to analyze fluid dynamics within the microchannel. Results indicate that the propeller robot can achieve an MI of up to 98.94% at a 150 μm levitation height and 1500 rpm propeller speed within 3 s. Additionally, the study examines the impact of propeller speed, Reynolds number, and robot length on mixing performance, providing comprehensive guidance for optimizing microscale fluid mixing in lab-on-a-chip applications.</p>","PeriodicalId":18508,"journal":{"name":"Micromachines","volume":"16 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11767584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143039884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This paper proposes and designs a silicon-based negative capacitance field effect transistor (NCFET) to replace conventional MOSFETs as the rectifying device in RF-DC circuits, aiming to enhance the rectification efficiency under low-power density conditions. By combining theoretical analysis with device simulations, the impacts of the ferroelectric material anisotropy, ferroelectric layer thickness, and active region doping concentration on the device performance were systematically optimized. The proposed NCFET structure is tailored for microwave wireless power transmission applications. Based on the optimized NCFET, a half-wave rectifier circuit employing a novel diode connection configuration was constructed and verified through transient simulations. The results show that at a microwave frequency of 2.45 GHz, the designed NCFET rectifier achieves rectification efficiencies of 16.1% and 29.75% at input power densities of -10 dBm and -6 dBm, respectively, which are 7.15 and 2.3 times higher than those of conventional silicon-based MOS devices. Furthermore, it significantly outperforms CMOS rectifiers reported in the literature. This study demonstrates the superior rectification performance of the proposed NCFET under low-power density conditions, offering an efficient device solution for microwave wireless power transmission systems.
{"title":"A Negative Capacitance Field-Effect Transistor with High Rectification Efficiency for Weak-Energy 2.45 GHz Microwave Wireless Transmission.","authors":"Hualian Tang, Ailan Tang, Weifeng Liu, Jingxiang Huang, Jianjun Song, Wenjie Sun","doi":"10.3390/mi16010058","DOIUrl":"10.3390/mi16010058","url":null,"abstract":"<p><p>This paper proposes and designs a silicon-based negative capacitance field effect transistor (NCFET) to replace conventional MOSFETs as the rectifying device in RF-DC circuits, aiming to enhance the rectification efficiency under low-power density conditions. By combining theoretical analysis with device simulations, the impacts of the ferroelectric material anisotropy, ferroelectric layer thickness, and active region doping concentration on the device performance were systematically optimized. The proposed NCFET structure is tailored for microwave wireless power transmission applications. Based on the optimized NCFET, a half-wave rectifier circuit employing a novel diode connection configuration was constructed and verified through transient simulations. The results show that at a microwave frequency of 2.45 GHz, the designed NCFET rectifier achieves rectification efficiencies of 16.1% and 29.75% at input power densities of -10 dBm and -6 dBm, respectively, which are 7.15 and 2.3 times higher than those of conventional silicon-based MOS devices. Furthermore, it significantly outperforms CMOS rectifiers reported in the literature. This study demonstrates the superior rectification performance of the proposed NCFET under low-power density conditions, offering an efficient device solution for microwave wireless power transmission systems.</p>","PeriodicalId":18508,"journal":{"name":"Micromachines","volume":"16 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11767402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143039940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adaptive optics (AO) systems are capable of correcting wavefront aberrations caused by transmission media or defects in optical systems. The deformable mirror (DM) plays a crucial role as a component of the adaptive optics system. In this study, our focus is on analyzing the ability of a 97-element MEMS (Micro-Electro-Mechanical System) DM to correct blurred images of extended sources affected by atmospheric turbulence. The RUN optimizer is employed as the control method to evaluate the correction capability of the DM through simulations and physical experiments. Simulation results demonstrate that within 100 iterations, both the normalized gray variance and Strehl Ratio can converge, leading to an improvement in image quality by approximately 30%. In physics experiments, we observe an increase in normalized gray variance (NGV) from 0.53 to 0.97 and the natural image quality evaluation (NIQE) from 15.35 to 19.73, representing an overall improvement in image quality of about 28%. These findings can offer theoretical and technical support for applying MEMS DMs in correcting imaging issues related to extended sources degraded by wavefront aberrations.
{"title":"Wavefront Correction for Extended Sources Imaging Based on a 97-Element MEMS Deformable Mirror.","authors":"Huizhen Yang, Lingzhe Tang, Zhaojun Yan, Peng Chen, Wenjie Yang, Xianshuo Li, Yongqi Ge","doi":"10.3390/mi16010050","DOIUrl":"10.3390/mi16010050","url":null,"abstract":"<p><p>Adaptive optics (AO) systems are capable of correcting wavefront aberrations caused by transmission media or defects in optical systems. The deformable mirror (DM) plays a crucial role as a component of the adaptive optics system. In this study, our focus is on analyzing the ability of a 97-element MEMS (Micro-Electro-Mechanical System) DM to correct blurred images of extended sources affected by atmospheric turbulence. The RUN optimizer is employed as the control method to evaluate the correction capability of the DM through simulations and physical experiments. Simulation results demonstrate that within 100 iterations, both the normalized gray variance and Strehl Ratio can converge, leading to an improvement in image quality by approximately 30%. In physics experiments, we observe an increase in normalized gray variance (NGV) from 0.53 to 0.97 and the natural image quality evaluation (NIQE) from 15.35 to 19.73, representing an overall improvement in image quality of about 28%. These findings can offer theoretical and technical support for applying MEMS DMs in correcting imaging issues related to extended sources degraded by wavefront aberrations.</p>","PeriodicalId":18508,"journal":{"name":"Micromachines","volume":"16 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11767500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143040183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The SiC MOSFET with an integrated SBD (SBD-MOSFET) exhibits excellent performance in power electronics. However, the static and dynamic characteristics of this device are influenced by a multitude of parameters, and traditional TCAD simulation methods are often characterized by their complexity. Due to the increasing research on neural networks in recent years, such as the application of neural networks to the prediction of GaN JBS and Finfet devices, this paper considers the application of neural networks to the performance prediction of SiC MOSFET devices with an integrated SBD. This study introduces a novel approach utilizing neural network machine learning to predict the static and dynamic characteristics of the SBD-MOSFET. In this research, SBD-MOSFET devices are modeled and simulated using Sentaurus TCAD(2017) software, resulting in the generation of 625 sets of device structure and sample data, which serve as the sample set for the neural network. These input variables are then fed into the neural network for prediction. The findings indicate that the mean square error (MSE) values for the threshold voltage (Vth), breakdown voltage (BV), specific on-resistance (Ron), and total switching power dissipation (E) are 0.0051, 0.0031, 0.0065, and 0.0220, respectively, demonstrating a high degree of accuracy in the predicted values. Meanwhile, in the comparison of convolutional neural networks and machine learning, the CNN accuracy is much higher than the machine learning methods. This method of predicting device performance via neural networks offers a rapid means of designing SBD-MOSFETs with specified performance targets, thereby presenting significant advantages in accelerating research on SBD-MOSFET performance prediction.
{"title":"SiC MOSFET with Integrated SBD Device Performance Prediction Method Based on Neural Network.","authors":"Xiping Niu, Ling Sang, Xiaoling Duan, Shijie Gu, Peng Zhao, Tao Zhu, Kaixuan Xu, Yawei He, Zheyang Li, Jincheng Zhang, Rui Jin","doi":"10.3390/mi16010055","DOIUrl":"10.3390/mi16010055","url":null,"abstract":"<p><p>The SiC MOSFET with an integrated SBD (SBD-MOSFET) exhibits excellent performance in power electronics. However, the static and dynamic characteristics of this device are influenced by a multitude of parameters, and traditional TCAD simulation methods are often characterized by their complexity. Due to the increasing research on neural networks in recent years, such as the application of neural networks to the prediction of GaN JBS and Finfet devices, this paper considers the application of neural networks to the performance prediction of SiC MOSFET devices with an integrated SBD. This study introduces a novel approach utilizing neural network machine learning to predict the static and dynamic characteristics of the SBD-MOSFET. In this research, SBD-MOSFET devices are modeled and simulated using Sentaurus TCAD(2017) software, resulting in the generation of 625 sets of device structure and sample data, which serve as the sample set for the neural network. These input variables are then fed into the neural network for prediction. The findings indicate that the mean square error (MSE) values for the threshold voltage (Vth), breakdown voltage (BV), specific on-resistance (R<sub>on</sub>), and total switching power dissipation (E) are 0.0051, 0.0031, 0.0065, and 0.0220, respectively, demonstrating a high degree of accuracy in the predicted values. Meanwhile, in the comparison of convolutional neural networks and machine learning, the CNN accuracy is much higher than the machine learning methods. This method of predicting device performance via neural networks offers a rapid means of designing SBD-MOSFETs with specified performance targets, thereby presenting significant advantages in accelerating research on SBD-MOSFET performance prediction.</p>","PeriodicalId":18508,"journal":{"name":"Micromachines","volume":"16 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11767802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143039950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xue-Ping Li, Chao-Liang He, Jun-Fei Ji, Meng-Bing Yang, Yan Zhang, An-Xue Zhang, Wei Li
A novel common-aperture miniaturized antenna with wideband and dual-polarized characteristics is proposed, which consists of a circularly polarized (CP) and a linearly polarized (LP) antenna. The circularly polarized antenna stacked on the upper layer adopts asymmetrical ground and introduces the patch and T-type feed network. On this basis, the meshed reflector structure, which also works as a ground plane for the LP antenna, is added to reduce the influence on circular polarization and achieve directional radiation. The LP antenna stacked in the lower layer uses a monopole structure, and the coaxial feed line perforates the reflector, and thereby the common-aperture antennas are tightly stacked together from top to bottom. Simulation and test are in good accordance, and the results show that the two ports of the antenna are well matched in the range of 5.5 GHz to 7.8 GHz, where peak gains of 8.5 dB and 6 dB are realized for circular polarization and linear polarization, respectively. Moreover, the 3 dB axial ratio (AR) bandwidth of the CP antenna is 34.3% and the isolation between the two ports is better than 15 dB, suggesting potential applications in the relay platform or drone detection for signal transmission and reception.
{"title":"A Compact Broadband Common-Aperture Dual-Polarized Antenna for Drone Applications.","authors":"Xue-Ping Li, Chao-Liang He, Jun-Fei Ji, Meng-Bing Yang, Yan Zhang, An-Xue Zhang, Wei Li","doi":"10.3390/mi16010048","DOIUrl":"10.3390/mi16010048","url":null,"abstract":"<p><p>A novel common-aperture miniaturized antenna with wideband and dual-polarized characteristics is proposed, which consists of a circularly polarized (CP) and a linearly polarized (LP) antenna. The circularly polarized antenna stacked on the upper layer adopts asymmetrical ground and introduces the patch and T-type feed network. On this basis, the meshed reflector structure, which also works as a ground plane for the LP antenna, is added to reduce the influence on circular polarization and achieve directional radiation. The LP antenna stacked in the lower layer uses a monopole structure, and the coaxial feed line perforates the reflector, and thereby the common-aperture antennas are tightly stacked together from top to bottom. Simulation and test are in good accordance, and the results show that the two ports of the antenna are well matched in the range of 5.5 GHz to 7.8 GHz, where peak gains of 8.5 dB and 6 dB are realized for circular polarization and linear polarization, respectively. Moreover, the 3 dB axial ratio (AR) bandwidth of the CP antenna is 34.3% and the isolation between the two ports is better than 15 dB, suggesting potential applications in the relay platform or drone detection for signal transmission and reception.</p>","PeriodicalId":18508,"journal":{"name":"Micromachines","volume":"16 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11767652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143039936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In order to achieve high accuracy in interferometric direction-finding systems, antennas with a stable phase center in the working bandwidth are required. This article proposes a miniaturized loaded open-boundary quad-ridge horn (LOQRH) antenna with dimensions of 40 mm × 40 mm × 49 mm. First, to stabilize the phase center of the antenna, the design builds on the foundation of a quad-ridge horn antenna, where measures such as optimizing the ridge structure and introducing resistive loading were implemented to achieve size reduction. Second, electrically small-sized antennas are more susceptible to the effects of common-mode currents (CMCs), which can reduce the symmetry of the radiation pattern and the stability of the phase center. To avoid the generation of common-mode currents during operation, a self-balanced feed structure was introduced into the proposed antenna design. This structure establishes a balanced circuit and routes the feedline at the voltage null point, effectively suppressing the common-mode current. As a result, the miniaturization of the LOQRH antenna was achieved while ensuring the suppression of the common-mode current, thereby maintaining the stability of the antenna's electromagnetic performance. The measured results show that the miniaturized antenna has a small phase center change of less than 20.3 mm within 2-18 GHz, while the simulated phase center fluctuation is only 14.6 mm. In addition, when taking 18.5 mm in front of the antenna's feed point as the phase center, the phase fluctuation is less than 22.5° within the required beam width. Along with the desired stable phase center, the miniaturized design makes the proposed antenna suitable for interferometric direction-finding systems.
{"title":"A Miniaturized Loaded Open-Boundary Quad-Ridge Horn with a Stable Phase Center for Interferometric Direction-Finding Systems.","authors":"Zibin Weng, Chen Liang, Kaibin Xue, Ziming Lv, Xing Zhang","doi":"10.3390/mi16010044","DOIUrl":"10.3390/mi16010044","url":null,"abstract":"<p><p>In order to achieve high accuracy in interferometric direction-finding systems, antennas with a stable phase center in the working bandwidth are required. This article proposes a miniaturized loaded open-boundary quad-ridge horn (LOQRH) antenna with dimensions of 40 mm × 40 mm × 49 mm. First, to stabilize the phase center of the antenna, the design builds on the foundation of a quad-ridge horn antenna, where measures such as optimizing the ridge structure and introducing resistive loading were implemented to achieve size reduction. Second, electrically small-sized antennas are more susceptible to the effects of common-mode currents (CMCs), which can reduce the symmetry of the radiation pattern and the stability of the phase center. To avoid the generation of common-mode currents during operation, a self-balanced feed structure was introduced into the proposed antenna design. This structure establishes a balanced circuit and routes the feedline at the voltage null point, effectively suppressing the common-mode current. As a result, the miniaturization of the LOQRH antenna was achieved while ensuring the suppression of the common-mode current, thereby maintaining the stability of the antenna's electromagnetic performance. The measured results show that the miniaturized antenna has a small phase center change of less than 20.3 mm within 2-18 GHz, while the simulated phase center fluctuation is only 14.6 mm. In addition, when taking 18.5 mm in front of the antenna's feed point as the phase center, the phase fluctuation is less than 22.5° within the required beam width. Along with the desired stable phase center, the miniaturized design makes the proposed antenna suitable for interferometric direction-finding systems.</p>","PeriodicalId":18508,"journal":{"name":"Micromachines","volume":"16 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11767410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143039939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this paper, we present a method based on the conjugate image principle and micro-nano optics to detect tilt aberrations of a phased fiber laser array system. A co-aperture optics system was adapted to detect the tilt aberrations of a seven-element phased fiber laser array system simultaneously. A Kepler telescope was designed to construct the conjugate relation between the exit pupil of a fiber optic laser array system and a microlens array and also to match the size of the seven beams and the microlens array. The apochromatic theory was used to meet the multispectral (1064 ± 0.3 nm, 1030 ± 0.3 nm, and 633 ± 0.2 nm) detection needs. A far-field detection unit was also designed to evaluate beam quality. When the actual beam was offset by 1 pixel, the beam tilt was about 0.7 µrad. The maximum detection error of the seven-element system was about 7 µrad. It could not only directly detect the beam's tilt angle but also maintained detection accuracy while reducing the algorithm complexity.
{"title":"Beam Tilt Aberration Detection of the Seven-Unit Phased Fiber Laser Array.","authors":"Xin Yu, Xingyue Wang, Jing Liang, Cai Liu, Xiaolong Ni, Suping Bai, Jiasu Li, Zeping Liu, Lijie Hou","doi":"10.3390/mi16010038","DOIUrl":"10.3390/mi16010038","url":null,"abstract":"<p><p>In this paper, we present a method based on the conjugate image principle and micro-nano optics to detect tilt aberrations of a phased fiber laser array system. A co-aperture optics system was adapted to detect the tilt aberrations of a seven-element phased fiber laser array system simultaneously. A Kepler telescope was designed to construct the conjugate relation between the exit pupil of a fiber optic laser array system and a microlens array and also to match the size of the seven beams and the microlens array. The apochromatic theory was used to meet the multispectral (1064 ± 0.3 nm, 1030 ± 0.3 nm, and 633 ± 0.2 nm) detection needs. A far-field detection unit was also designed to evaluate beam quality. When the actual beam was offset by 1 pixel, the beam tilt was about 0.7 µrad. The maximum detection error of the seven-element system was about 7 µrad. It could not only directly detect the beam's tilt angle but also maintained detection accuracy while reducing the algorithm complexity.</p>","PeriodicalId":18508,"journal":{"name":"Micromachines","volume":"16 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11767342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143039877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
An automated micro-tweezers system with a flexible workspace would benefit the intelligent sorting of live cells. Such micro-tweezers could employ a forced vortex strong enough to capture a single cell. Furthermore, addressable control of the position to the vortex would constitute a robotic system. In this study, a spherical micro-object composed of super paramagnetic particles tightly packed in a non-magnetic resin is rotated with a combined magnetic field of permanent magnets. The said magnetic field is articulated by an open-kinematic chain controlled with a simple adaptive PI-control scheme. A vortex is formed as the spherical particle, assumed to be submerged under the surface of fluid, and follows the position and orientation of the external magnetic field. This forced vortex induces a radial pressure gradient that captures the live cell orbiting around the spherical object combined with the inertial effects. Here, a comprehensive mathematical model is presented to reflect on the dynamics of such micro-tweezer systems. Numerical results demonstrate that it is theoretically possible to capture and tow a bacterium cell while meeting extreme tracking references for motion control. Magnetic and fluid forces on the spherical particle traverse the vortex and the bacterium cell, with orbiting and sporadic collusion of the bacterium cell around the spherical particle, and the positions of the end-effector, i.e., the magnets, are analyzed.
{"title":"Multi-Scale Robotics: A Numerical Investigation on Mobile Micro-Tweezers for Micro-Manipulation with Extreme Requirements.","authors":"Ahmet Fatih Tabak","doi":"10.3390/mi16010040","DOIUrl":"10.3390/mi16010040","url":null,"abstract":"<p><p>An automated micro-tweezers system with a flexible workspace would benefit the intelligent sorting of live cells. Such micro-tweezers could employ a forced vortex strong enough to capture a single cell. Furthermore, addressable control of the position to the vortex would constitute a robotic system. In this study, a spherical micro-object composed of super paramagnetic particles tightly packed in a non-magnetic resin is rotated with a combined magnetic field of permanent magnets. The said magnetic field is articulated by an open-kinematic chain controlled with a simple adaptive PI-control scheme. A vortex is formed as the spherical particle, assumed to be submerged under the surface of fluid, and follows the position and orientation of the external magnetic field. This forced vortex induces a radial pressure gradient that captures the live cell orbiting around the spherical object combined with the inertial effects. Here, a comprehensive mathematical model is presented to reflect on the dynamics of such micro-tweezer systems. Numerical results demonstrate that it is theoretically possible to capture and tow a bacterium cell while meeting extreme tracking references for motion control. Magnetic and fluid forces on the spherical particle traverse the vortex and the bacterium cell, with orbiting and sporadic collusion of the bacterium cell around the spherical particle, and the positions of the end-effector, i.e., the magnets, are analyzed.</p>","PeriodicalId":18508,"journal":{"name":"Micromachines","volume":"16 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11767921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143039887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The development of bionic organ-on-a-chip technology relies heavily on advancements in in situ sensors and biochip packaging. By integrating precise biological and fluid condition sensing with microfluidics and electronic components, long-term dynamic closed-loop culture systems can be achieved. This study aims to develop biocompatible heterogeneous packaging and laser surface modification techniques to enable the encapsulation of electronic components while minimizing their impact on fluid dynamics. Using a kidney-on-a-chip as a case study, a non-toxic packaging process and fluid interface control methods have been successfully developed. Experimentally, miniature pressure sensors and control circuit boards were encapsulated using parylene-C, a biocompatible material, to isolate biochemical fluids from electronic components. Ultraviolet laser processing was employed to fabricate structures on parylene-C. The results demonstrate that through precise control of processing parameters, the wettability of the material can be tuned freely within a contact angle range of 60° to 110°. Morphological observations and MTT assays confirmed that the material and the processing methods do not induce cytotoxicity. This technology will facilitate the packaging of various miniature electronic components and biochips in the future. Furthermore, laser processing enables rapid and precise control of interface conditions across different regions within the chip, demonstrating a high potential for customized mass production of biochips. The proposed innovations provide a solution for in situ sensing in organ-on-a-chip systems and advanced biochip packaging. We believe that the development of this technology is a critical step toward realizing the concept of "organ twin".
{"title":"Biocompatible Heterogeneous Packaging and Laser-Assisted Fluid Interface Control for In Situ Sensor in Organ-on-a-Chip.","authors":"Yu-Hsuan Lin, Shing-Fung Lau, Yen-Pei Lu, Kuo-Cheng Huang, Chien-Fang Ding, Yu-Hsiang Tang, Hsin-Yi Tsai","doi":"10.3390/mi16010046","DOIUrl":"10.3390/mi16010046","url":null,"abstract":"<p><p>The development of bionic organ-on-a-chip technology relies heavily on advancements in in situ sensors and biochip packaging. By integrating precise biological and fluid condition sensing with microfluidics and electronic components, long-term dynamic closed-loop culture systems can be achieved. This study aims to develop biocompatible heterogeneous packaging and laser surface modification techniques to enable the encapsulation of electronic components while minimizing their impact on fluid dynamics. Using a kidney-on-a-chip as a case study, a non-toxic packaging process and fluid interface control methods have been successfully developed. Experimentally, miniature pressure sensors and control circuit boards were encapsulated using parylene-C, a biocompatible material, to isolate biochemical fluids from electronic components. Ultraviolet laser processing was employed to fabricate structures on parylene-C. The results demonstrate that through precise control of processing parameters, the wettability of the material can be tuned freely within a contact angle range of 60° to 110°. Morphological observations and MTT assays confirmed that the material and the processing methods do not induce cytotoxicity. This technology will facilitate the packaging of various miniature electronic components and biochips in the future. Furthermore, laser processing enables rapid and precise control of interface conditions across different regions within the chip, demonstrating a high potential for customized mass production of biochips. The proposed innovations provide a solution for in situ sensing in organ-on-a-chip systems and advanced biochip packaging. We believe that the development of this technology is a critical step toward realizing the concept of \"organ twin\".</p>","PeriodicalId":18508,"journal":{"name":"Micromachines","volume":"16 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11767515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143039878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jihyun Park, Jongmin Choi, Jihye Seo, Wolil Nam, Soobeom Lee, Seungchan Cho, Kyungchul Park, Geonhyoung An, Beomkyeong Park, Moonhee Choi
Developing thin-film sheets made of oxide-based solid electrolytes is essential for fabricating surface-mounted ultracompact multilayer oxide solid-state batteries. To this end, solid-electrolyte slurry must be optimized for excellent dispersibility. Although oxide-based solid electrolytes for multilayer structures require sintering, high processing temperatures cause problems such as Li-ion volatilization and reactions with graphite anodes. Thus, low-temperature sinterable oxide-based solid-electrolyte materials should be devised. We successfully developed the conditions for producing thin films from 21 μm thick solid-electrolyte sheets of Li2O-B2O3-Al2O3, one of the most promising candidates for multilayer solid-state batteries. A comprehensive analysis of the fabricated thin films included X-ray diffraction (XRD) to confirm their amorphous structure, scanning electron microscopy (SEM) for particle morphology, and contact angle measurements to verify surface hydrophilicity. Evaluation of a 32-layer bulk sample of solid-electrolyte sheets revealed an ionic conductivity of 2.33 × 10-7 S/cm and charge transfer resistance of 100.1 kΩ at a sintering temperature of 430 °C. Based on these results, cathode and anode active materials will be applied to develop high-energy-density multilayer ceramic batteries with hundreds of layers in future work.
{"title":"Slurry Synthesis and Thin-Film Fabrication Toward Production of Li₂O-B₂O₃-Al₂O₃-Based Multilayer Oxide Solid-State Batteries for Internet of Things Applications.","authors":"Jihyun Park, Jongmin Choi, Jihye Seo, Wolil Nam, Soobeom Lee, Seungchan Cho, Kyungchul Park, Geonhyoung An, Beomkyeong Park, Moonhee Choi","doi":"10.3390/mi16010039","DOIUrl":"10.3390/mi16010039","url":null,"abstract":"<p><p>Developing thin-film sheets made of oxide-based solid electrolytes is essential for fabricating surface-mounted ultracompact multilayer oxide solid-state batteries. To this end, solid-electrolyte slurry must be optimized for excellent dispersibility. Although oxide-based solid electrolytes for multilayer structures require sintering, high processing temperatures cause problems such as Li-ion volatilization and reactions with graphite anodes. Thus, low-temperature sinterable oxide-based solid-electrolyte materials should be devised. We successfully developed the conditions for producing thin films from 21 μm thick solid-electrolyte sheets of Li<sub>2</sub>O-B<sub>2</sub>O<sub>3</sub>-Al<sub>2</sub>O<sub>3</sub>, one of the most promising candidates for multilayer solid-state batteries. A comprehensive analysis of the fabricated thin films included X-ray diffraction (XRD) to confirm their amorphous structure, scanning electron microscopy (SEM) for particle morphology, and contact angle measurements to verify surface hydrophilicity. Evaluation of a 32-layer bulk sample of solid-electrolyte sheets revealed an ionic conductivity of 2.33 × 10<sup>-7</sup> S/cm and charge transfer resistance of 100.1 kΩ at a sintering temperature of 430 °C. Based on these results, cathode and anode active materials will be applied to develop high-energy-density multilayer ceramic batteries with hundreds of layers in future work.</p>","PeriodicalId":18508,"journal":{"name":"Micromachines","volume":"16 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11767993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143039955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}