Background: In recent decades, violent behavior towards women has been considered as the most serious social problem beyond cultural, social, and regional boundaries. This type of violence includes any violent sexual action which causes physical, sexual, or mental damage in women, leading to obligatory deprivation from individual or social freedom. Objectives: The present study was aimed to examine levels of domestic abuse and emotional regulation in normal women and women exposed to violence. Methods: This study is causal-comparative and of an after-event type. The statistical population of the present study consisted of two groups of women: exposed-to-violence women with background in conflict intervention and social emergency centers; and normal women in the second half of 2015. Statistical sample included 200 individuals (100 exposed-to-violence women and 100 normal women), who were selected using Convenience Sampling method; and they were examined and compared using questionnaires of domestic abuse and emotional regulation. All analytical actions were done using SPSS-ver20. Results: Data analysis showed that there is a significant difference between exposed-to-violence women and normal women in terms of domestic abuse dimensions (emotional adjustment components) (P > 0.0001). The results of the multivariate analysis of variance showed that there is a significant difference between the two groups of women in terms of the three subscales of domestic abuse questionnaire (emotional, physical, and sexual misbehavior); and comparison of mean values showed that the degree of these dimensions in exposed-to-violence women is high. Conclusions: Results showed that exposed-to-violence women experience more physical, sexual, and emotional domestic abuse. This can also be related to their differences in terms of emotional adjustment, which must be cared about by experts in order to give better service to these women and prevent social damage.
{"title":"Comparing Levels of Domestic Abuse and Emotional Regulation of Normal Women and Women Exposed to Violence","authors":"B. Akbari, S. Sadeghi, Zainab Sirus Jahedi","doi":"10.5812/RIJM.61402","DOIUrl":"https://doi.org/10.5812/RIJM.61402","url":null,"abstract":"Background: In recent decades, violent behavior towards women has been considered as the most serious social problem beyond cultural, social, and regional boundaries. This type of violence includes any violent sexual action which causes physical, sexual, or mental damage in women, leading to obligatory deprivation from individual or social freedom. Objectives: The present study was aimed to examine levels of domestic abuse and emotional regulation in normal women and women exposed to violence. Methods: This study is causal-comparative and of an after-event type. The statistical population of the present study consisted of two groups of women: exposed-to-violence women with background in conflict intervention and social emergency centers; and normal women in the second half of 2015. Statistical sample included 200 individuals (100 exposed-to-violence women and 100 normal women), who were selected using Convenience Sampling method; and they were examined and compared using questionnaires of domestic abuse and emotional regulation. All analytical actions were done using SPSS-ver20. Results: Data analysis showed that there is a significant difference between exposed-to-violence women and normal women in terms of domestic abuse dimensions (emotional adjustment components) (P > 0.0001). The results of the multivariate analysis of variance showed that there is a significant difference between the two groups of women in terms of the three subscales of domestic abuse questionnaire (emotional, physical, and sexual misbehavior); and comparison of mean values showed that the degree of these dimensions in exposed-to-violence women is high. Conclusions: Results showed that exposed-to-violence women experience more physical, sexual, and emotional domestic abuse. This can also be related to their differences in terms of emotional adjustment, which must be cared about by experts in order to give better service to these women and prevent social damage.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43272343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soheila Jafarpour, Hoshang Jadidi, S. A. H. Almadani
Background: Various aspects of the psychological component have been affected by the spread of social networks and using these networks by the students. Objectives: This study aimed to examine the personality traits, mental health and self-esteem in users and non-users of social net-
{"title":"Comparing Personality Traits, Mental Health and Self-Esteem in Users and Non-Users of Social Networks","authors":"Soheila Jafarpour, Hoshang Jadidi, S. A. H. Almadani","doi":"10.5812/RIJM.61401","DOIUrl":"https://doi.org/10.5812/RIJM.61401","url":null,"abstract":"Background: Various aspects of the psychological component have been affected by the spread of social networks and using these networks by the students. Objectives: This study aimed to examine the personality traits, mental health and self-esteem in users and non-users of social net-","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47398657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Adolescence is a sensitive stage of life, where adolescents experience considerable emotional, physical, and intellectual changes. Hence, any delay in emotional maturity might be followed by serious problems in interpersonal relationships of adolescents as well as social challenges; the criterion for determination of social growth is the ability to adapt to others. Objectives: The present study aimed to examine the relationships between life expectancy as well as social intelligence and adaptability to the mediating role of resistance in high school boys in Tehran. Methods: It was a correlational descriptive study; the statistical population consisted of all high school boys in Tehran, from whom 250 students were selected by cluster sampling method. Data collection was based on Snyder’s et al. (1991) Life Expectancy standard questionnaire, Silvera’s et al. (2001) Social Intelligence questionnaire as well as Sinha and Sing’s (1993) Adaptability questionnaire. Results: The results showed that there is a significant relationship between life expectancy as well as social intelligence and the mediating role of resistance in high school boys in Tehran. It also showed that there is a significant relationship between life expectancy as well as adaptability dimensions (emotional, educational, and social) and the mediating role of resistance in high school boys in Tehran. Finally, it showed that there is a significant relationship between social intelligence well as adaptability dimensions (emotional, educational, and social) and the mediating role of resistance in high school boys. Conclusions: Based on the results, it can be stated that resistance plays an intermediary role in life expectancy and social intelligence with social adjustment.
{"title":"Relationship between Life Expectancy as well as Social Intelligence and Adaptability to the Mediating Role of Resistance in High School Boys","authors":"R. Padam, M. Nickname","doi":"10.5812/RIJM.57473","DOIUrl":"https://doi.org/10.5812/RIJM.57473","url":null,"abstract":"Background: Adolescence is a sensitive stage of life, where adolescents experience considerable emotional, physical, and intellectual changes. Hence, any delay in emotional maturity might be followed by serious problems in interpersonal relationships of adolescents as well as social challenges; the criterion for determination of social growth is the ability to adapt to others. Objectives: The present study aimed to examine the relationships between life expectancy as well as social intelligence and adaptability to the mediating role of resistance in high school boys in Tehran. Methods: It was a correlational descriptive study; the statistical population consisted of all high school boys in Tehran, from whom 250 students were selected by cluster sampling method. Data collection was based on Snyder’s et al. (1991) Life Expectancy standard questionnaire, Silvera’s et al. (2001) Social Intelligence questionnaire as well as Sinha and Sing’s (1993) Adaptability questionnaire. Results: The results showed that there is a significant relationship between life expectancy as well as social intelligence and the mediating role of resistance in high school boys in Tehran. It also showed that there is a significant relationship between life expectancy as well as adaptability dimensions (emotional, educational, and social) and the mediating role of resistance in high school boys in Tehran. Finally, it showed that there is a significant relationship between social intelligence well as adaptability dimensions (emotional, educational, and social) and the mediating role of resistance in high school boys. Conclusions: Based on the results, it can be stated that resistance plays an intermediary role in life expectancy and social intelligence with social adjustment.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48870263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The Basal-Like breast cancer, is always known for lack of expression of estrogen receptor (ER), progesterone receptor (PR) and as well, absence of epidermal growth factor receptor 2 (HER2) gene amplification. Improper expression pattern of ER, PR, and Her2, makes Basal-Like breast tumors resistant to the current hormonal and anti HER2 treatments. In recent decades, several studies have been conducted to investigate the regulatory role of chemical modifications of core histones in gene expression. Their results have shown that histone acetylation is involved in regulation of cell survival. Acetylation of core histones is regulated by the epigenetic-modifying enzymes named Histone Deacetylases (HDACs). As a new approach to control the viability of breast tumor cells resistant to the hormonal and anti-HER2 treatments, we have targeted the HDACs. Using Trichostatin A (TSA) as a known HDACs inhibitor, we have tried to hyperacetylate the core histones of MDA-MB-231 cells as an in vitro model of Basal-Like breast tumors. Then we have investigated the effect of histone hyperacetylation on viability of MDA-MB-231 cells. Methods: MDA-MB-231 cells were cultured in RPMI 1640 medium containing 10% fetal bovine serum (FBS) and were incubated at 37°C, in a humidified incubator with 5% CO2 atmosphere. Then cells were treated with different concentrations of TSA including: 50, 100, 200, 400, 800 and 1000 nM or control (1% DMSO). After 24 and 48 hours, viability of cells was evaluated by MTT assay. Results: After 24 and 48h exposure to different concentrations of TSA, MDA-MB-231 cells showed a maximum tolerable dose. At higher concentrations, TSA decreased the percentage of cell viability through a time-dose dependent manner. IC50 value for 48h treatment was 600 nM. Conclusions: Our results indicate that HDACs inhibition and subsequently hyperacetylation of histones, leads to cytotoxic effects on breast tumor cells resistant to the current treatments. Following this pilot research we are trying to suggest molecular mechanisms underlying the anti-proliferative effects triggered by HDACs inhibition.
{"title":"The Effect of Histone Hyperacetylation on Viability of Basal-Like Breast Cancer Cells MDA-MB-231","authors":"A. Rahimian, A. Mellati","doi":"10.5812/RIJM.55455","DOIUrl":"https://doi.org/10.5812/RIJM.55455","url":null,"abstract":"Background: The Basal-Like breast cancer, is always known for lack of expression of estrogen receptor (ER), progesterone receptor (PR) and as well, absence of epidermal growth factor receptor 2 (HER2) gene amplification. Improper expression pattern of ER, PR, and Her2, makes Basal-Like breast tumors resistant to the current hormonal and anti HER2 treatments. In recent decades, several studies have been conducted to investigate the regulatory role of chemical modifications of core histones in gene expression. Their results have shown that histone acetylation is involved in regulation of cell survival. Acetylation of core histones is regulated by the epigenetic-modifying enzymes named Histone Deacetylases (HDACs). As a new approach to control the viability of breast tumor cells resistant to the hormonal and anti-HER2 treatments, we have targeted the HDACs. Using Trichostatin A (TSA) as a known HDACs inhibitor, we have tried to hyperacetylate the core histones of MDA-MB-231 cells as an in vitro model of Basal-Like breast tumors. Then we have investigated the effect of histone hyperacetylation on viability of MDA-MB-231 cells. Methods: MDA-MB-231 cells were cultured in RPMI 1640 medium containing 10% fetal bovine serum (FBS) and were incubated at 37°C, in a humidified incubator with 5% CO2 atmosphere. Then cells were treated with different concentrations of TSA including: 50, 100, 200, 400, 800 and 1000 nM or control (1% DMSO). After 24 and 48 hours, viability of cells was evaluated by MTT assay. Results: After 24 and 48h exposure to different concentrations of TSA, MDA-MB-231 cells showed a maximum tolerable dose. At higher concentrations, TSA decreased the percentage of cell viability through a time-dose dependent manner. IC50 value for 48h treatment was 600 nM. Conclusions: Our results indicate that HDACs inhibition and subsequently hyperacetylation of histones, leads to cytotoxic effects on breast tumor cells resistant to the current treatments. Following this pilot research we are trying to suggest molecular mechanisms underlying the anti-proliferative effects triggered by HDACs inhibition.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42171775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Organophosphate compounds cause poisoning and death more than any other insecticide. These toxins can cause peripheral neuropathy which is delayed for about 3 6 weeks and no method has been known for predicting the incidence. It has been claimed that electrophysiological tests (EMG NCV) can help in predicting the disorder. Objectives: The main purpose of this research was to study EMG NCV tests in patients with moderate to severe organophosphate poisoning. Methods: This was a cross-sectional study conducted on patients with moderate to severe organophosphate poisoning from 2014 to 2016 in Imam Reza hospital of Mashhad. The minimum sample size was calculated as 68 patients and then all data was collected on the basis of inclusion and exclusion criteria using data collection form designed by the researcher, and finally data were analyzed using SPSS V.21 software, descriptive tests (including mean, median, mode) and analytical tests (K square, ANOVA). Results: Of all 78 patients with the mean age of 27.50± 10.0, 45 were female and the rest were male. Totally 29.5% of the patients had abnormal EMG NCV. Although no significant differences were observed between electro diagnostic tests (EMG NCV) and age, gender, clinical symptoms and levels of acetylcholinesterase serum activity, the relationship between EMG NCV and RBC levels of acetylcholinesterase activity was significant. Conclusions: Electrophysiological tests are not associated with clinical symptoms (muscle weakness) and they cannot be considered as a determining factor to discharge the patients; therefore, careful examination of the patients or evaluating the level of AChE activity in red blood cells is needed.
{"title":"Evaluating Diagnostic Value of Electrophysiological Testing (EMG-NCV) Compared to the Activity Level of Acetylcholinesterase in Serum and Red Blood Cells of Patients with Moderate to Severe Organophosphate Poisoning","authors":"F. Najari, A. Ghamsari, S. Mousavi, Bita Daadpour","doi":"10.5812/RIJM.44107","DOIUrl":"https://doi.org/10.5812/RIJM.44107","url":null,"abstract":"Background: Organophosphate compounds cause poisoning and death more than any other insecticide. These toxins can cause peripheral neuropathy which is delayed for about 3 6 weeks and no method has been known for predicting the incidence. It has been claimed that electrophysiological tests (EMG NCV) can help in predicting the disorder. Objectives: The main purpose of this research was to study EMG NCV tests in patients with moderate to severe organophosphate poisoning. Methods: This was a cross-sectional study conducted on patients with moderate to severe organophosphate poisoning from 2014 to 2016 in Imam Reza hospital of Mashhad. The minimum sample size was calculated as 68 patients and then all data was collected on the basis of inclusion and exclusion criteria using data collection form designed by the researcher, and finally data were analyzed using SPSS V.21 software, descriptive tests (including mean, median, mode) and analytical tests (K square, ANOVA). Results: Of all 78 patients with the mean age of 27.50± 10.0, 45 were female and the rest were male. Totally 29.5% of the patients had abnormal EMG NCV. Although no significant differences were observed between electro diagnostic tests (EMG NCV) and age, gender, clinical symptoms and levels of acetylcholinesterase serum activity, the relationship between EMG NCV and RBC levels of acetylcholinesterase activity was significant. Conclusions: Electrophysiological tests are not associated with clinical symptoms (muscle weakness) and they cannot be considered as a determining factor to discharge the patients; therefore, careful examination of the patients or evaluating the level of AChE activity in red blood cells is needed.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47013920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. A. Rad, Abdollah Firoozi, Fatemeh Akbarirad, M. H. Daloee, S. Bonakdaran
Background: In this study we assessed the relationship between corrected-QT intervals and other ECG characteristics with methadone dose and other parameters in MMT patients and healthy subjects. Methods: This was a case-control study which was carried out on patients underwent MMT and healthy control group who had been referred to Ebne-Sina academic hospital, Mashhad during 2014 2015. At the time of the study, 40 patients who received MMT therapy for at least 6 months and 40 voluntary healthy subjects who matched on age and sex enrolled in the study. 12-lead ECG was performed for all the patients. Mean QT interval, PR interval and QRS duration in every 12 leads were documented for each patient
{"title":"Relationship between Corrected-QT Intervals and Other ECG Characteristics with Methadone Dose in Methadone Maintenance Treatment (MMT) Patients and Healthy Subjects: A Case- Control Study","authors":"M. A. Rad, Abdollah Firoozi, Fatemeh Akbarirad, M. H. Daloee, S. Bonakdaran","doi":"10.5812/RIJM.13642","DOIUrl":"https://doi.org/10.5812/RIJM.13642","url":null,"abstract":"Background: In this study we assessed the relationship between corrected-QT intervals and other ECG characteristics with methadone dose and other parameters in MMT patients and healthy subjects. Methods: This was a case-control study which was carried out on patients underwent MMT and healthy control group who had been referred to Ebne-Sina academic hospital, Mashhad during 2014 2015. At the time of the study, 40 patients who received MMT therapy for at least 6 months and 40 voluntary healthy subjects who matched on age and sex enrolled in the study. 12-lead ECG was performed for all the patients. Mean QT interval, PR interval and QRS duration in every 12 leads were documented for each patient","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43643229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: This research aimed to study the effectiveness of “parent training based on the Choice Theory” on the motherdaughter conflicts and increasing mothers’ sense of self-efficacy. Methods: The quasi-experimental method was used to examine the research variables. The research population included a group of mothers of the students who were in sixth to ninth grade at Nure Narges school in region 5 of Tehran. The parentadolescent conflict questionnaire (teen’s papers) was used to assess the frequency and intensity of the conflict. A group of 24 volunteer mothers whose daughters had reported the most conflicts with their mothers was randomly assigned to the experimental and control groups. Both groups filled the parentadolescent conflict questionnaire. The experimental group were trained parenting skills based on the Choice Theory for 8 sessions, while the control group were not trained. Finally, both groups answered the questionnaire again. They also answered the questionnaires three months later, as a follow-up. Multivariate analysis of covariance was used for data
{"title":"Parent Training Based on the Choice Theory: Analysis of its Impact on Mothers’ Sense of Self-efficacy and their Conflicts with their Daughters","authors":"Monireh Hosseini, A. Esmaeili, A. Sahebi","doi":"10.5812/RIJM.13929","DOIUrl":"https://doi.org/10.5812/RIJM.13929","url":null,"abstract":"Background: This research aimed to study the effectiveness of “parent training based on the Choice Theory” on the motherdaughter conflicts and increasing mothers’ sense of self-efficacy. Methods: The quasi-experimental method was used to examine the research variables. The research population included a group of mothers of the students who were in sixth to ninth grade at Nure Narges school in region 5 of Tehran. The parentadolescent conflict questionnaire (teen’s papers) was used to assess the frequency and intensity of the conflict. A group of 24 volunteer mothers whose daughters had reported the most conflicts with their mothers was randomly assigned to the experimental and control groups. Both groups filled the parentadolescent conflict questionnaire. The experimental group were trained parenting skills based on the Choice Theory for 8 sessions, while the control group were not trained. Finally, both groups answered the questionnaire again. They also answered the questionnaires three months later, as a follow-up. Multivariate analysis of covariance was used for data","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44690246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Hosseini, A. Fazlinezhad, M. Jalalyazdi, Azadeh Mahmoodi Gharaee, L. Hosseini, M. Andalibi
Background: Some hypertensive patients experience dyspnea with exercise due to rise in filling pressures. So, exercise is helpful to determine left ventricular filling tension. Objectives: This study aims to evaluate the effect of dobutamine stress echocardiography on diastolic function in hypertensive patients with normal ejection fraction. Methods: In this study, 30 hypertensive patients (52.7 ± 3.6 years) and 30 sex and age matched healthy controls (50.8 ± 7.6 years) were examined. Exclusion criteria were patients with coronary artery disease, significant valvular heart disease, hypertrophic cardiomyopathy, left ventricular systolic dysfunction (EF (ejection fraction) < 50%), atrial fibrillation and bad echogenic view. We performed complete echocardiography and dobutamine stress echocardiography with pulsed wave Doppler tissue imaging at rest and during peak stress to measure primary mitral inflow diastolic wave rate (E), late mitral inflow diastolic wave rate (A), E/A ratio, primary diastolic myocardial wave rate (E′) and late diastolic myocardial wave velocity (A’). Results: At rest, E’ was significantly lower in patients than controls (8.2± 1.6 vs 14.7± 2.6 P value < 0.001) and E/E (early mitral inflow diastolic wave rate/early myocardial diastolic wave rate) was significantly higher in patients (7.6± 1.2 vs 4.8± 1.0 P value <0.001). At peak stress, E/A ratio was significantly lower in patients (P < 0.001) while E/E′ was significantly higher in patients than controls (8.3 ± 2.1 vs 4.7 ± 0.7 P value < 0.001). Conclusions: Dobutamine stress echocardiography with Doppler tissue study is effective in the evaluation of hypertensive patients with dyspnea on exertion with normal resting echocardiography.
背景:一些高血压患者在运动时由于充盈压升高而出现呼吸困难。因此，运动有助于确定左心室充盈张力。目的:探讨多巴酚丁胺应激超声心动图对射血分数正常的高血压患者舒张功能的影响。方法:选取30例高血压患者(52.7±3.6岁)和30例性别、年龄匹配的健康对照(50.8±7.6岁)。排除标准为冠心病、有明显瓣膜病、肥厚性心肌病、左室收缩功能不全(EF(射血分数)< 50%)、心房颤动、超声检查不良者。我们在静息和应激峰值时进行全超声心动图和多巴酚丁胺应激超声心动图及脉冲波多普勒组织成像，测量二尖瓣初级流入舒张波率(E)、二尖瓣晚期流入舒张波率(A)、E/A比值、初级舒张心肌波率(E′)和舒张晚期心肌波速度(A′)。结果:静息时，患者E′显著低于对照组(8.2±1.6 vs 14.7±2.6 P值<0.001)，E/E(早期二尖瓣流入舒张波率/早期心肌舒张波率)显著高于对照组(7.6±1.2 vs 4.8±1.0 P值<0.001)。应激峰值时，患者E/A比显著低于对照组(P < 0.001)，而E/E′显著高于对照组(P值8.3±2.1 vs 4.7±0.7)。结论:多巴酚丁胺应激超声心动图联合多普勒组织研究对正常静息超声心动图评价高血压呼吸困难患者运动时的表现是有效的。
{"title":"Diastolic Function Changes during Stress Echocardiography in Hypertensive Patients","authors":"S. Hosseini, A. Fazlinezhad, M. Jalalyazdi, Azadeh Mahmoodi Gharaee, L. Hosseini, M. Andalibi","doi":"10.5812/RIJM.42876","DOIUrl":"https://doi.org/10.5812/RIJM.42876","url":null,"abstract":"Background: Some hypertensive patients experience dyspnea with exercise due to rise in filling pressures. So, exercise is helpful to determine left ventricular filling tension. Objectives: This study aims to evaluate the effect of dobutamine stress echocardiography on diastolic function in hypertensive patients with normal ejection fraction. Methods: In this study, 30 hypertensive patients (52.7 ± 3.6 years) and 30 sex and age matched healthy controls (50.8 ± 7.6 years) were examined. Exclusion criteria were patients with coronary artery disease, significant valvular heart disease, hypertrophic cardiomyopathy, left ventricular systolic dysfunction (EF (ejection fraction) < 50%), atrial fibrillation and bad echogenic view. We performed complete echocardiography and dobutamine stress echocardiography with pulsed wave Doppler tissue imaging at rest and during peak stress to measure primary mitral inflow diastolic wave rate (E), late mitral inflow diastolic wave rate (A), E/A ratio, primary diastolic myocardial wave rate (E′) and late diastolic myocardial wave velocity (A’). Results: At rest, E’ was significantly lower in patients than controls (8.2± 1.6 vs 14.7± 2.6 P value < 0.001) and E/E (early mitral inflow diastolic wave rate/early myocardial diastolic wave rate) was significantly higher in patients (7.6± 1.2 vs 4.8± 1.0 P value <0.001). At peak stress, E/A ratio was significantly lower in patients (P < 0.001) while E/E′ was significantly higher in patients than controls (8.3 ± 2.1 vs 4.7 ± 0.7 P value < 0.001). Conclusions: Dobutamine stress echocardiography with Doppler tissue study is effective in the evaluation of hypertensive patients with dyspnea on exertion with normal resting echocardiography.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45019769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Ghazanfarpour, T. Khadivzade, Elham Arghavani, H. Kareshki
Background: Thereisapaucitystudiesonpartners’ discussionsaboutchildbearinginIran. Toshedsomelightonthisunderstud-ied subject, we need to develop a valid and reliable instrument at first. Objectives: To formulate a questionnaire that evaluates the responsible participation of couples in childbearing decision making. Methods: In this paper, a mixed-method sequential explanatory design was used to design the proper instrument. The questionnaire was developed and tested in three stages. In stage 1, an item pool was generated. In stage 2, content validity was assessed and in stage 3, validity (exploratory factor analysis and confirmatory factor analysis) was performed. Results: At the first step, a 13-item instrument was designed, with the results yielding a content validity index of 0.80 for the instrument. The principal component analysis was applied to a sample population consisting of 450 couples to identify the factor structure of the inventory. According to the results, values of 4.458 (df = 78, P < 0.001) and 0.84 were obtained for Bartlett’s test of sphericity and Kaiser-Meyer-Olkin (KMO) measure of sampling adequacy respectively. As such, three factors with a total variance of 62% were extracted, out of which four factors had acceptable reliability with a Cronbach’s alpha of 0.60 to 0.85. The results of confirmatory analysis of RPCF questionnaire demonstrated the acceptable fitness of the model (CFI = 0.95 TLI = 0.94 and RMSEA = 0.05 and x 2 / df = 2.99). Conclusions: Our results showed that the instrument consisted of three dimensions and exhibits high internal consistency. Also this study approved the use of RPCFQ to measure responsible participation of couples in childbearing.
{"title":"An Investigation of the Factor Structure and Validity of Responsible Participation of Couples in Childbearing Scale","authors":"M. Ghazanfarpour, T. Khadivzade, Elham Arghavani, H. Kareshki","doi":"10.5812/RIJM.43355","DOIUrl":"https://doi.org/10.5812/RIJM.43355","url":null,"abstract":"Background: Thereisapaucitystudiesonpartners’ discussionsaboutchildbearinginIran. Toshedsomelightonthisunderstud-ied subject, we need to develop a valid and reliable instrument at first. Objectives: To formulate a questionnaire that evaluates the responsible participation of couples in childbearing decision making. Methods: In this paper, a mixed-method sequential explanatory design was used to design the proper instrument. The questionnaire was developed and tested in three stages. In stage 1, an item pool was generated. In stage 2, content validity was assessed and in stage 3, validity (exploratory factor analysis and confirmatory factor analysis) was performed. Results: At the first step, a 13-item instrument was designed, with the results yielding a content validity index of 0.80 for the instrument. The principal component analysis was applied to a sample population consisting of 450 couples to identify the factor structure of the inventory. According to the results, values of 4.458 (df = 78, P < 0.001) and 0.84 were obtained for Bartlett’s test of sphericity and Kaiser-Meyer-Olkin (KMO) measure of sampling adequacy respectively. As such, three factors with a total variance of 62% were extracted, out of which four factors had acceptable reliability with a Cronbach’s alpha of 0.60 to 0.85. The results of confirmatory analysis of RPCF questionnaire demonstrated the acceptable fitness of the model (CFI = 0.95 TLI = 0.94 and RMSEA = 0.05 and x 2 / df = 2.99). Conclusions: Our results showed that the instrument consisted of three dimensions and exhibits high internal consistency. Also this study approved the use of RPCFQ to measure responsible participation of couples in childbearing.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46090666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The purpose of this research was to investigate the role of specialized translators and interpreters of medical discourse in bringing satisfaction to health tourists. The goal was to find the effect of non-professional medical interpreters (translators) in breaking efficient patient-physician relationship. Nowadays, most foreign patients are accompanied by someone who is not familiar with medical terminology and just thanks to knowing a language he/she becomes an interpreter of a foreign patient. Ten foreign patients from different countries were investigated in this report. Based on the gathered data, three findings could be concluded: Firstly, nonprofessional interpreters could not usually interpret medical terminologies accurately. Secondly, trained specialized translators can bring satisfaction to health tourists and help them with successful course of treatment. Thirdly, patients themselves were aware of non-professional translators’ misinterpretations which lead to dissatisfaction and considering other destinations for treatment.
{"title":"The Role of Medical Translator/Interpreter in Bringing Satisfaction to Health Tourists at Razavi Hospital","authors":"M. Fallah, Omid Akbari","doi":"10.5812/RIJM.42739","DOIUrl":"https://doi.org/10.5812/RIJM.42739","url":null,"abstract":"The purpose of this research was to investigate the role of specialized translators and interpreters of medical discourse in bringing satisfaction to health tourists. The goal was to find the effect of non-professional medical interpreters (translators) in breaking efficient patient-physician relationship. Nowadays, most foreign patients are accompanied by someone who is not familiar with medical terminology and just thanks to knowing a language he/she becomes an interpreter of a foreign patient. Ten foreign patients from different countries were investigated in this report. Based on the gathered data, three findings could be concluded: Firstly, nonprofessional interpreters could not usually interpret medical terminologies accurately. Secondly, trained specialized translators can bring satisfaction to health tourists and help them with successful course of treatment. Thirdly, patients themselves were aware of non-professional translators’ misinterpretations which lead to dissatisfaction and considering other destinations for treatment.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49337247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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