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Enhanced magnetic field sensing using geometric-mediated whispering gallery mode resonators 增强磁场感应使用几何介导低语画廊模式谐振器
IF 4.9 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-12 DOI: 10.1016/j.sna.2026.117458
Amir R. Ali , Yasmin Yousry , Alaa El Anssary
The development of highly sensitive magnetic field sensors is critical for applications in biomedical diagnostics, wearable technologies, and environmental monitoring. While conventional research focuses on material composition, the influence of geometric configuration remains largely unexplored. This study demonstrates the profound impact of macroscopic shape on the sensitivity of magnetorheological (MR) nanocomposite sensors. Initial macroscopic experiments with pyramid-like structures revealed unexpected localized magnetic field perturbations, challenging the assumption that only material properties dictate field interactions. Inspired by these findings, we fabricated a novel optical fiber magnetic field sensor using magnetic nanoparticles dispersed within a polydimethylsiloxane (PDMS) matrix. The sensor's performance was evaluated by subjecting it to a controlled harmonic magnetic field using a neodymium magnet. Our comparative analysis revealed that a conventional spherical sensor had a limited sensitivity of 0.0065 pm/mT and a resolution of ∼ 2mT. In contrast, an innovatively designed pyramidal sensor exhibited a remarkable sensitivity of 35.098 pm/µT, achieving a resolution of ∼ 0.2 µT. This represents a groundbreaking enhancement of over 5 million times in sensitivity and an improvement of nearly four orders of magnitude in resolution. We attribute this unprecedented amplification to the geometrical concentration of magnetic flux within the pyramidal shape, a finding that highlights the critical role of macroscopic geometry in dictating the performance of advanced sensing platforms and presents a promising pathway for the development of next-generation, ultrasensitive magnetic field detectors in different industrial and bio medical applications.
高灵敏度磁场传感器的开发对于生物医学诊断、可穿戴技术和环境监测的应用至关重要。虽然传统的研究主要集中在材料成分上,但几何结构的影响在很大程度上仍未被探索。本研究证明了宏观形状对磁流变(MR)纳米复合传感器灵敏度的深远影响。金字塔状结构的初始宏观实验揭示了意想不到的局部磁场扰动,挑战了只有材料性质决定场相互作用的假设。受这些发现的启发,我们利用分散在聚二甲基硅氧烷(PDMS)基质中的磁性纳米颗粒制造了一种新型光纤磁场传感器。通过将传感器置于钕磁铁控制的谐波磁场中,对传感器的性能进行了评估。我们的比较分析表明,传统的球形传感器的有限灵敏度为0.0065 pm/mT,分辨率为~ 2mT。相比之下,创新设计的金字塔传感器具有35.098 pm/µT的显着灵敏度,实现了~ 0.2µT的分辨率。这代表了灵敏度超过500万倍的突破性提高,分辨率提高了近四个数量级。我们将这种前所未有的放大归因于金字塔形状内磁通量的几何集中,这一发现突出了宏观几何在决定先进传感平台性能方面的关键作用,并为不同工业和生物医学应用中开发下一代超灵敏磁场探测器提供了一条有希望的途径。
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引用次数: 0
Contactless point-of-care detection of latent tuberculosis biomarker Hsp16.3 using a high-sensitivity magnetoimpedance biosensor 使用高灵敏度磁阻抗生物传感器检测潜伏性结核生物标志物Hsp16.3的非接触式护理点
IF 4.9 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-12 DOI: 10.1016/j.sna.2026.117493
Thimpika Pornprom , Bongkochawan Pakamwong , Jidapa Sangswan , Auradee Punkvang , Paptawan Thongdee , Khomson Suttisintong , Jiraporn Leanpolchareanchai , Poonpilas Hongmanee , Putthapoom Lumjiaktase , Orawon Chailapakul , Sakda Jampasa , Pornpan Pungpo , Ongard Thiabgoh
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), remains a leading cause of infectious disease-related mortality worldwide, with latent tuberculosis infection (LTBI) presenting a major diagnostic challenge. Heat shock protein 16.3 (Hsp16.3), a latency-associated antigen strongly expressed during dormancy, has emerged as a promising biomarker for LTBI detection. However, conventional diagnostic methods are costly, complex, and infrastructure-dependent, underscoring the need for portable and reagent-free biosensing solutions. Here, we report a contactless biosensing platform based on the giant magnetoimpedance (GMI) effect for the detection of Hsp16.3. The system integrates a commercial pico-Tesla resolution amorphous wire sensor with an Arduino-based microcontroller and MCP3223 analog-to-digital converter. Detection relies on binding-induced magnetic field perturbations generated by antibody- functionalized iron-oxide nanoparticles, and antibody-antigen complexes, which modulate the local magnetic fields and induce measurable impedance changes. The biosensor achieved reproducible detection of Hsp16.3 in model assays, with limits of detection of ∼99 µg/mL for antibody titration and ∼44 µg/mL for antigen response. More importantly, the platform was successfully validated with plasma samples from LTBI patients, demonstrating specific responses to antibody-antigen complexes in complex biological matrices. This work represents the first demonstration of a GMI-biosensor validated with LTBI plasma samples, highlighting its potential as a portable, scalable, and reagent-free diagnostic tool for future development toward early TB screening in resource-limited settings.
由结核分枝杆菌(MTB)引起的结核病(TB)仍然是世界范围内传染病相关死亡的主要原因,潜伏性结核感染(LTBI)提出了一个主要的诊断挑战。热休克蛋白16.3 (Hsp16.3)是一种在休眠期间强烈表达的潜伏期相关抗原,已成为LTBI检测的有希望的生物标志物。然而,传统的诊断方法昂贵、复杂且依赖于基础设施,因此需要便携式和无试剂的生物传感解决方案。本文报道了一种基于巨磁阻抗(GMI)效应的检测Hsp16.3的非接触式生物传感平台。该系统集成了商用pico-Tesla分辨率非晶线传感器、基于arduino的微控制器和MCP3223模数转换器。检测依赖于由抗体功能化的氧化铁纳米颗粒和抗体-抗原复合物产生的结合诱导的磁场扰动,它们调节局部磁场并诱导可测量的阻抗变化。该生物传感器在模型分析中实现了对Hsp16.3的重复性检测,抗体滴定的检测限为~ 99 µg/mL,抗原反应的检测限为~ 44 µg/mL。更重要的是,该平台成功地用LTBI患者的血浆样本进行了验证,显示出对复杂生物基质中抗体-抗原复合物的特异性反应。这项工作首次展示了用LTBI血浆样本验证的gmi -生物传感器,突出了其作为便携式、可扩展和无试剂诊断工具的潜力,可用于未来在资源有限的环境中开发早期结核病筛查。
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引用次数: 0
A flexible self-powered pentacene/Ga2O3 heterojunction solar-blind ultraviolet photodetector 柔性自供电的并五苯/Ga2O3异质结太阳盲紫外探测器
IF 4.9 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-12 DOI: 10.1016/j.sna.2026.117488
Chenglong Zhou, Yongsheng Tan, Anbiao Gui, Shunwei Zhu, Shunhang Wei, Zebo Fang, Qiufeng Ye
In this work, a self-powered pentacene/Ga2O3 heterojunction solar-blind ultraviolet (UV) photodetector was fabricated on a flexible mica substrate using magnetron sputtering and thermal evaporation. The device exhibits excellent self-powered characteristics under 254 nm solar-blind UV illumination. Under 254 nm irradiation with an intensity of 200 μW/cm2 at 0 V bias, the device achieved a responsivity of 2.11 mA/W, a specific detectivity of 3.05×1011 Jones, and a photo-to-dark current ratio of 2800. The rise and fall times were 0.69 s and 1.39 s, respectively. Furthermore, mechanical bending tests were conducted on the flexible device. After 700 bending cycles at a 30, no significant degradation was observed in the current–voltage characteristics or the responsivity at 0 V bias, demonstrating its outstanding mechanical robustness.
在这项工作中,利用磁控溅射和热蒸发技术,在柔性云母衬底上制作了自供电的并五苯/Ga2O3异质结太阳盲紫外(UV)光电探测器。该器件在254 nm太阳盲紫外光照下表现出优异的自供电特性。在254 nm、200 μW/cm2、0 V偏置照射下,器件的响应率为2.11 mA/W,比探测率为3.05×1011 Jones,光暗电流比为2800。上升和下降时间分别为0.69 s和1.39 s。并对柔性装置进行了机械弯曲试验。在30°下弯曲700次后,没有观察到电流-电压特性或0 V偏置下的响应性有明显的下降,显示了它出色的机械稳健性。
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引用次数: 0
Smart nanoprobes in diabetes management: Emerging role of carbon quantum dots in diagnosis and therapy 智能纳米探针在糖尿病管理:碳量子点在诊断和治疗中的新兴作用
IF 4.9 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-12 DOI: 10.1016/j.sna.2026.117490
Basila A.K. , Desu Gayathri Niharika , CS Krishna Murthy , K.Sandeep Raju , Punam Salaria , Amarendar Reddy M.
Insulin, a peptide hormone crucial for glucose homeostasis, is produced by the beta cells of the pancreatic islets of Langerhans. An imbalance in glucose metabolism can lead to diabetes mellitus, a chronic metabolic disorder. This imbalance can result from insufficient production or the body’s inability to effectively use the insulin it produces because of structural abnormalities or cellular resistance. The prevalence of diabetes is steadily increasing worldwide. Early and accurate detection of diabetes is crucial for effective treatment, prevention, and symptom management. In this discussion, we highlight the significance of Carbon Quantum Dots (CQDs), carbon-based nanoparticles (typically < 10 nm), in diabetes detection and their potential role in therapeutic applications for diabetes-related complications. We also explore various synthesis methods of CQDs, their characterization techniques, and different CQD-based sensors, along with their underlying detection mechanisms.
胰岛素是一种对葡萄糖稳态至关重要的肽激素,由朗格汉斯胰岛的β细胞产生。葡萄糖代谢失衡可导致糖尿病,这是一种慢性代谢紊乱。这种不平衡可能是由于结构异常或细胞抵抗导致胰岛素分泌不足或身体无法有效利用其产生的胰岛素。糖尿病的患病率在世界范围内稳步上升。糖尿病的早期和准确检测对于有效的治疗、预防和症状管理至关重要。在本讨论中,我们强调了碳量子点(CQDs),碳基纳米颗粒(通常为10 nm)在糖尿病检测中的重要性及其在糖尿病相关并发症治疗应用中的潜在作用。我们还探讨了cqd的各种合成方法、表征技术和不同的cqd传感器,以及它们的潜在检测机制。
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引用次数: 0
Piezoelectric sonic black hole for broadband energy harvesting 用于宽带能量收集的压电声波黑洞
IF 4.9 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-12 DOI: 10.1016/j.sna.2026.117487
Lihua Peng , Qibo Mao , Ziyan Chen , Xiaohang Hu , Ping Cai
In this study, an acoustic energy harvester (AEH) composed of a Sonic black hole (SBH) and a circular piezoelectric composite sheet (PCS) is proposed. As sound waves propagate through the SBH structure, their amplitude increases and the waves become concentrated at the SBH termination. In the proposed AEH, the SBH is used to amplify the incident sound pressure and enable the energy of the incident sound wave to be fully converted into electrical energy through the PCS. The proposed AEH was evaluated using theoretical calculations, numerical simulation and experimental tests. The results indicate that the SBH exhibits a significant sound pressure amplification effect. Final, the AEH was fabricated by 3D printing. Experimental results show that the half-absorption bandwidth of AEH is 523 Hz within the frequency range of 50–1000 Hz. The maximum output power of AEH is 8 μW and the maximum power conversion efficiency of the AEH is almost 100 % under the optimal load resistance (5000 Ω). The proposed AEH features an efficient, easy-to-integrate structure, making it versatile for use in acoustic energy harvesters and absorbers.
本文提出了一种由声波黑洞(SBH)和圆形压电复合片(PCS)组成的声能收集器(AEH)。当声波通过SBH结构传播时,其振幅增加,波在SBH末端集中。在本文提出的AEH中,SBH用于放大入射声压,并使入射声波的能量通过PCS充分转化为电能。通过理论计算、数值模拟和实验测试对所提出的AEH进行了评价。结果表明,SBH具有显著的声压放大效应。最后,采用3D打印技术制作AEH。实验结果表明,在50 ~ 1000 Hz的频率范围内,AEH的半吸收带宽为523 Hz。在最佳负载电阻(5000 Ω)下,AEH的最大输出功率为8 μW,最大功率转换效率接近100 %。所提出的AEH具有高效,易于集成的结构,使其在声能收集器和吸收器中用途广泛。
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引用次数: 0
Thermally tuned long-range surface plasmon resonance sensor for in situ detection of oil mixture in edible oils 用于食用油中油脂混合物原位检测的热调谐远程表面等离子体共振传感器
IF 4.9 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-11 DOI: 10.1016/j.sna.2026.117485
Mohd Hafiz Abu Bakar , Wan Mohd Ebtisyam Mustaqim Mohd Daniyal , Muhammad Qayyum Othman , Athiyah Sakinah Masran , Nur Hidayah Azeman , Muhammad Asif Ahmad Khushaini , Retna Apsari , Mohd Adzir Mahdi , Mohammed Thamer Alresheedi , Fairuz Abdullah , Ahmad Ashrif A. Bakar
Long-Range Surface Plasmon Resonance (LRSPR) has emerged as a promising sensing technique for detecting compositional changes in oil mixtures. In this study, LRSPR was applied to monitor the mixing of edible oil with mineral oil under different thermal conditions (30 °C and 50 °C). The resonance response at 30 °C exhibited a non-linear calibration profile with an overall sensitivity of 5.60 nm/% (R² = 0.997). Region I (0–10 %) showed a sensitivity of 1.39 nm/% (R² = 0.9545, LOD = 0.45 %), while Region II (10–50 %) demonstrated strong linearity with 6.63 nm/% (R² = 0.993). At 50 °C, the overall sensitivity decreased to 3.47 nm/% (R² = 0.991), with Region I (0–30 %) suppressed to 0.64 nm/% (R² = 0.792, LOD = 0.61 %), and Region II (30–50 %) regaining a steeper slope of 7.89 nm/% (R² = 0.991). Elevated temperature was found to broaden resonance features, reduce peak intensity, and increase damping, consistent with the Drude model. Despite these effects, the sensor maintained reliable detection performance across both temperature conditions. These findings highlight LRSPR as a sensitive and versatile platform for in situ screening of edible oil mixtures, offering robust detection even under variable thermal environments.
远程表面等离子体共振(LRSPR)是一种很有前途的检测石油混合物成分变化的传感技术。本研究采用LRSPR对不同热条件(30℃和50℃)下食用油与矿物油的混合进行监测。30°C时的共振响应呈现非线性校准曲线,总体灵敏度为5.60 nm/% (R²= 0.997)。区域1(0 ~ 10 %)的灵敏度为1.39 nm/% (R²= 0.9545,LOD = 0.45 %),区域2(10 ~ 50 %)的线性关系为6.63 nm/% (R²= 0.993)。在50°C时,总灵敏度下降到3.47 nm/% (R²= 0.991),其中区域I(0-30 %)被抑制到0.64 nm/% (R²= 0.792,LOD = 0.61 %),区域II(30-50 %)恢复到7.89 nm/% (R²= 0.991)。发现温度升高会拓宽共振特征,降低峰值强度,增加阻尼,与德鲁德模型一致。尽管存在这些影响,传感器在两种温度条件下都保持可靠的检测性能。这些发现突出了LRSPR作为一个敏感和通用的平台,用于食用油混合物的原位筛选,即使在可变的热环境下也能提供强大的检测。
{"title":"Thermally tuned long-range surface plasmon resonance sensor for in situ detection of oil mixture in edible oils","authors":"Mohd Hafiz Abu Bakar ,&nbsp;Wan Mohd Ebtisyam Mustaqim Mohd Daniyal ,&nbsp;Muhammad Qayyum Othman ,&nbsp;Athiyah Sakinah Masran ,&nbsp;Nur Hidayah Azeman ,&nbsp;Muhammad Asif Ahmad Khushaini ,&nbsp;Retna Apsari ,&nbsp;Mohd Adzir Mahdi ,&nbsp;Mohammed Thamer Alresheedi ,&nbsp;Fairuz Abdullah ,&nbsp;Ahmad Ashrif A. Bakar","doi":"10.1016/j.sna.2026.117485","DOIUrl":"10.1016/j.sna.2026.117485","url":null,"abstract":"<div><div>Long-Range Surface Plasmon Resonance (LRSPR) has emerged as a promising sensing technique for detecting compositional changes in oil mixtures. In this study, LRSPR was applied to monitor the mixing of edible oil with mineral oil under different thermal conditions (30 °C and 50 °C). The resonance response at 30 °C exhibited a non-linear calibration profile with an overall sensitivity of 5.60 nm/% (R² = 0.997). Region I (0–10 %) showed a sensitivity of 1.39 nm/% (R² = 0.9545, LOD = 0.45 %), while Region II (10–50 %) demonstrated strong linearity with 6.63 nm/% (R² = 0.993). At 50 °C, the overall sensitivity decreased to 3.47 nm/% (R² = 0.991), with Region I (0–30 %) suppressed to 0.64 nm/% (R² = 0.792, LOD = 0.61 %), and Region II (30–50 %) regaining a steeper slope of 7.89 nm/% (R² = 0.991). Elevated temperature was found to broaden resonance features, reduce peak intensity, and increase damping, consistent with the Drude model. Despite these effects, the sensor maintained reliable detection performance across both temperature conditions. These findings highlight LRSPR as a sensitive and versatile platform for <em>in situ</em> screening of edible oil mixtures, offering robust detection even under variable thermal environments.</div></div>","PeriodicalId":21689,"journal":{"name":"Sensors and Actuators A-physical","volume":"399 ","pages":"Article 117485"},"PeriodicalIF":4.9,"publicationDate":"2026-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimisation of adhesive-free high-frequency miniature class IV transducers incorporating single-element piezoelectric plates 包含单元件压电板的无粘合剂高频微型IV类换能器的优化
IF 4.9 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-11 DOI: 10.1016/j.sna.2026.117489
Xuan Li , Yifei Wang , Youheng Zeng , Dongliang Shi , Zhihong Huang , Kwok-Ho Lam
Tissue biopsy under regional anaesthesia requires accurate localisation of the needle tip during penetration through skin and soft tissue. To enhance needle tip visibility in colour Doppler imaging, ultrasonically actuated needle systems based on bolted Langevin transducers have been developed. However, these systems impose design constraints as the needle length must be tuned to the transducer resonance, and their relatively large size limits the suitability for hand-held procedures. Flextensional transducers offer a compact alternative, enabling large displacement with minimal bulk piezoelectric material. This paper presents an optimisation study of three metal shell geometries for class IV miniature flextensional transducers, excited by hard piezoelectric plates to maximise displacement amplification. The transducers employ a negative interference fit between the piezoelectric plate and metal shell, introducing structural pre-stress without bonding or transition mechanisms. Additionally, the dynamic response and power density of the transducers are evaluated for different active materials, including piezoceramics (Pz54) and piezocrystals (Mn:PIN-PMN-PT). Experimental results show that, for identical dimensions, the Mn:PIN-PMN-PT transducer achieves a lower resonant frequency, reduced and near-resistive impedance, enhanced electromechanical coupling, higher mechanical Q, and increased power density compared with the piezoceramic counterpart.
区域麻醉下的组织活检需要针头在穿透皮肤和软组织时准确定位。为了提高彩色多普勒成像中针尖的可见性,基于螺栓朗格万换能器的超声驱动针系统已经被开发出来。然而,这些系统施加了设计限制,因为针头长度必须调整到换能器共振,并且它们相对较大的尺寸限制了手持式程序的适用性。弯张换能器提供了一种紧凑的替代方案,可以用最小的体积压电材料实现大位移。本文提出了一个优化研究的三种金属外壳几何形状的IV类微型弯张换能器,由硬压电板激发,以最大限度地扩大位移。换能器在压电板和金属外壳之间采用负干涉配合,在没有粘合或过渡机制的情况下引入结构预应力。此外,对不同活性材料(包括压电陶瓷(Pz54)和压电晶体(Mn:PIN-PMN-PT))下换能器的动态响应和功率密度进行了评估。实验结果表明,在相同尺寸下,Mn:PIN-PMN-PT换能器比压电陶瓷换能器具有更低的谐振频率、更低的近阻阻抗、更强的机电耦合、更高的机械Q和更高的功率密度。
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引用次数: 0
A flexible miniatured wearable device for monitoring lactic acid and pH in sweat 一种灵活的微型可穿戴设备,用于监测汗液中的乳酸和pH值
IF 4.9 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-10 DOI: 10.1016/j.sna.2026.117478
Shengzhao Zhang , Jiaxin Li , Xinrui Qiu , Lei Xuan , Yuyang Xu , Jian Li , Haibo Xing , Guangli Liu , Runhuai Yang
Wearable sensor devices are crucial for monitoring physiological states and biochemical markers. A device that combines circuit miniaturization with accurate biochemical monitoring is essential for achieving long-term, continuous physiological tracking without burdening the user. In this paper, we introduce a flexible miniatured wearable device for simultaneous monitoring of sweat pH and lactate. The device is composed of a miniatured wireless flexible printed circuit board (FPCB, 25 mm×11 mm) and a flexible polyaniline (PANI) sensing patch which has good linearity, stability, and ion selectivity. Every component on the FPCB was meticulously selected to achieve a compact form factor, and a guard ring structure was used in the PCB layout to reduce the voltage decrease of the pH sensing patch. The resulting flexible, miniatured, and wearable (FMW) device features a low minimum detection volume threshold (20 μL) making it well-suited for low-volume biofluids such as sweat, which is typically secreted gradually rather than abundantly. Practical applicability was demonstrated through tests on artificial sweat, volunteer sweat, and other samples, confirming the accuracy for non-invasive monitoring. The low-power design enables prolonged operation, supporting continuous use for over 10 days. This FMW system enables for dual sweat biomarker monitoring and holds significant promise for providing user-friendly health assessments.
可穿戴传感器设备对于监测生理状态和生化指标至关重要。将电路小型化与精确的生化监测相结合的设备对于实现长期、连续的生理跟踪而不给用户带来负担至关重要。在本文中,我们介绍了一种灵活的微型可穿戴设备,用于同时监测汗液pH和乳酸。该器件由微型无线柔性印刷电路板(FPCB, 25 mm×11 mm)和柔性聚苯胺(PANI)传感贴片组成,具有良好的线性度、稳定性和离子选择性。FPCB上的每个元件都经过精心选择,以实现紧凑的外形因素,并且在PCB布局中使用保护环结构,以减少pH传感贴片的电压降低。由此产生的柔性,小型化和可穿戴(FMW)设备具有低最小检测体积阈值(20 μL),使其非常适合小体积生物流体,如汗液,这通常是逐渐分泌而不是大量分泌。通过对人工汗液、志愿者汗液等样本的测试,验证了其实用性,证实了其无创监测的准确性。低功耗设计可延长工作时间,支持连续使用10天以上。该FMW系统可实现双汗液生物标志物监测,并有望提供用户友好的健康评估。
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引用次数: 0
Voiceprint features and CNN for label-free identification of Na-alginate microdroplet size and concentration during high-frequency generation 声纹特征和CNN用于无标签识别海藻酸钠微滴在高频产生过程中的大小和浓度
IF 4.9 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-10 DOI: 10.1016/j.sna.2026.117467
Peng-Nian Chen, Chia-Hung Dylan Tsai
A voiceprint-based method was developed for label-free and non-contact identification of Na-alginate microdroplet properties during high-frequency (1 kHz) generation using a simple microphone setup. The generation of alginate microdroplets enables mass production in applications such as drug delivery and cell encapsulation, while the monitoring of droplets’ properties remains challenging. Conventional labeling-based or electrical methods can be costly and intrusive. In this study, sounds emitted from a coaxial microfluidic device were analyzed via short-time Fourier transform (STFT), and spectral features were input into a convolutional neural network (CNN) for droplet concentration estimation. Experimental results show that the sound’s spectral energy increased by 1.5 fold as the droplet diameter increased from 60 to 120 μm, attributed by varying the inner capillary diameter from 10 to 30 μm. Changes in Na-alginate concentration from 0.0 to 2.0 wt.% produced systematic shifts in spectral centroid and bandwidth, reflecting variations in droplet viscosity. The CNN model achieved a concentration estimation accuracy with a root mean square error of 0.1 wt.%. These results demonstrate that the proposed voiceprint-based approach provides a simple, accurate, and cost-effective alternative for monitoring microdroplet properties, while its millisecond-level detection speed makes the method practical for rapid microencapsulation and other fast-throughput processes.
利用简单的麦克风设置,开发了一种基于声纹的方法,用于在高频(~ 1 kHz)产生过程中无标签和非接触地鉴定海藻酸钠微滴的性质。海藻酸盐微滴的产生使药物输送和细胞封装等应用的大规模生产成为可能,但对微滴性质的监测仍然具有挑战性。传统的基于标签或电的方法可能是昂贵的和侵入性的。本研究通过短时傅里叶变换(STFT)对同轴微流控装置发出的声音进行分析,并将频谱特征输入卷积神经网络(CNN)进行液滴浓度估计。实验结果表明,当液滴直径从60 μm增加到120 μm时,声谱能量增加了1.5倍,这是由于内部毛细直径从10 μm增加到30 μm所致。海藻酸钠浓度从0.0 wt.%到2.0 wt.%的变化产生了光谱质心和带宽的系统变化,反映了液滴粘度的变化。CNN模型达到了浓度估计精度,均方根误差为0.1 wt.%。这些结果表明,所提出的基于声纹的方法为监测微滴特性提供了一种简单、准确、经济的替代方法,而其毫秒级的检测速度使该方法适用于快速微封装和其他快速吞吐过程。
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引用次数: 0
Geometry optimization of printed piezoresistive sensors for catheter monitoring 导管监测用印刷压阻式传感器的几何优化
IF 4.9 3区 工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-10 DOI: 10.1016/j.sna.2026.117483
E. Pimentel , S.G. Pereira , J.L. Vilaça , C.M. Costa , S. Lanceros-Méndez , D. Miranda
An increasing number of biomedical applications would benefit to implement printed piezoresistive sensors for improving device performance and sensor integration. In specific, in urinary catheters used to address urinary incontinence and retention, the implementation of piezoresistive sensors would allow to monitor the deformation along the process of insertion, allowing to reduce or even eliminate some of the inconveniences of this type of procedures. This works reports the development of composite inks based on poly(D,L-lactide-co-glycolide) (PDLG) 50/50 with 2 % of multiwalled carbon nanotubes and the development by spray printing of piezoresistive sensors with two types of geometry: square and zig zag shape. The spray printed sensors demonstrate a Gauge factor in the range 0.8–1.2 for the zig-zag geometry and 0.3–1.1 for the rectangular geometry. A theoretical study was performed to evaluate the stress on the piezoresistive sensors and predict the mechanical behavior of the developed geometries proving that, when strain is applied in the longitudinal way, the rectangular geometry presented double the stress value in relation to the zig zag one. Finally, the zig zag geometry was selected for a proof of concept using a KUKA LBR iiwa 7R800 robot, proving the suitability of the developed sensors for applications. Overall, this work demonstrates that the implementation of piezoresistive sensors based on natural polymers in a zig zag geometry is a suitable approach for urinary catheter deformation monitoring.
越来越多的生物医学应用将有利于实现印刷压阻传感器,以提高设备性能和传感器集成。具体来说,在用于解决尿失禁和尿潴留的导尿管中,压阻式传感器的实施将允许监测插入过程中的变形,从而减少甚至消除此类手术的一些不便。本文报道了基于聚(D, l -丙交酯-羟基乙醇酸酯)(PDLG) 50/50和2 %多壁碳纳米管的复合油墨的发展,以及通过喷涂打印具有两种几何形状的压阻传感器的发展:正方形和之字形。喷印传感器的测量系数范围为0.8-1.2 之字形几何形状和0.3-1.1 矩形几何形状。通过理论研究,对压阻式传感器的应力进行了评估,并预测了所开发几何形状的力学行为,证明了当应变以纵向方式施加时,矩形几何形状的应力值是之字形几何形状的两倍。最后,使用库卡LBR iiwa 7R800机器人选择之字形几何形状进行概念验证,证明开发的传感器适用于应用。总的来说,这项工作表明,基于天然聚合物的z形几何压阻传感器的实现是一种适用于导尿管变形监测的方法。
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引用次数: 0
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Sensors and Actuators A-physical
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