Resting hand tremor, a prevalent neurological disorder, significantly compromises patients’ quality of life without being directly life-threatening. Conventional pharmacological and surgical interventions are often costly and carry potential complications, thereby generating considerable interest in non-invasive wearable assistive devices. However, existing exoskeleton-based tremor suppression devices, which predominantly rely on conventional motor-driven mechanisms, are frequently hampered by issues such as large size, substantial weight, and significant obtrusiveness. These limitations readily induce muscle fatigue, severely restricting their clinical utility and patient compliance. To address these challenges, this study pioneers the application of multilayer polyvinyl chloride (PVC) gel actuators for hand tremor suppression. Aiming to develop a practical suppression device, we first identified the optimal parameter set by investigating the force/displacement characteristics of the actuator under varying plasticizer contents and stacking layers. This established a high-performance gel actuator configuration suitable for tremor suppression, upon which a modular encapsulation structure with adjustable pre-tension was designed. Subsequently, guided by the principles of active vibration control, a dedicated control system was developed, incorporating tremor signal frequency/phase detection and a voltage-source switching control strategy. Finally, a hand tremor simulation test platform was constructed for validation. Experimental results demonstrated that the multilayer PVC gel actuator achieved a suppression efficiency of up to 49%. The encapsulated actuator exhibited outstanding comprehensive performance, including low power dissipation (5.2%), rapid response (50 ms), high operational bandwidth (10 Hz), and lightweight (33 g), thereby fully validating its application potential in physiological tremor suppression.
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