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The 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems最新文献

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A Dual Mode Neural Signal Recording System for synchronous neuroeletrical and neurochemical detection 用于同步神经电和神经化学检测的双模式神经信号记录系统
Shengwei Xu, Nansen Lin, Dalei Wang, Wenjing Yu, W. Shi, Tingjun Jiang, Xinxia Cai
This paper presents a 64-channel Dual Mode Neural Signal Recording System (DMNSRS) for detection of neuroeletrical and neurochemical signals. The DMNSRS comprises neurochemical recording module with current resolution of 1 pA and neuroelectricity recording module with voltage resolution of 0.3 μV. The two modules can work synchronously without mutual interference. In a global cerebral ischemia experiment, using Multi-Electrode Arrays (MEA) as neurobiological electrode and a single-walled carbon nanotube (SWNT)-modified glassy carbon electrode as neurochemical working electrode, the neuroelectrical and neurochemical signals are synchronously recorded by the DMNSRS in the Sprague-Dawley (SD) rat cortex.
本文介绍了一种64通道双模神经信号记录系统(DMNSRS),用于检测神经电信号和神经化学信号。DMNSRS由电流分辨率为1 pA的神经化学记录模块和电压分辨率为0.3 μV的神经电记录模块组成。两个模块可以同步工作,互不干扰。在全脑缺血实验中,采用多电极阵列(MEA)作为神经生物电极,单壁碳纳米管(SWNT)修饰的玻碳电极作为神经化学工作电极,用DMNSRS同步记录SD大鼠皮层的神经电和神经化学信号。
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引用次数: 1
Cantilever arrayed blood pressure sensor for arterial applanation tonometry 用于动脉压平测压的悬臂式阵列血压传感器
Byeungleul Lee, Jinwoo Jeong, Chanseob Cho, Jinseok Kim, Bonghwan Kim, H. Kim, K. Chun
We developed a cantilever-arrayed blood pressure sensor array fabricated by (111) silicon bulk-micromachining for the noninvasive and continuous measurement of blood pressure. The blood pressure sensor measures the blood pressure based on the change in resistance of the piezoresistor on a 5-μm-thick-arrayed perforated membrane and 20-μm-thick metal pads. The length and width of the unit membrane are 210 and 310 μm, respectively. The width of the insensible zone between adjacent units is only 10 μm. The resistance change over contact force was measured to verify the performance. The good linearity of the result confirmed that the PDMS package transfers the forces appropriately. The measured sensitivity was about 4.5%/N. The maximum measurement range and resolution of the fabricated blood pressure sensor were greater than 900 mmHg and less than 1 mmHg, respectively.
我们开发了一种由(111)硅体微加工制成的悬臂式血压传感器阵列,用于无创连续测量血压。血压传感器是在5 μm厚的穿孔膜和20 μm厚的金属垫片上,通过压敏电阻的电阻变化来测量血压。单元膜的长度为210 μm,宽度为310 μm。相邻单元之间的不敏感区宽度仅为10 μm。通过测量电阻随接触力的变化来验证其性能。结果良好的线性关系证实了PDMS包能很好地传递力。测得的灵敏度约为4.5%/N。所制血压传感器的最大测量范围大于900 mmHg,分辨率小于1 mmHg。
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引用次数: 8
Fabrication and analysis optical microsphere cavity based on high Q erbium-doped 高Q掺铒光学微球腔的制备与分析
S. Yan, Xiao-Qian Wang, Kezhen Ma, An-fu Zhang, C. Xue, Wendong Zhang
Using CO2 laser metal method process the top of erbium-doped tapered fiber, which formed by stretching a standard optical fiber (SMF-125) while heating it with a hydrogen flame. The top of tapered fiber formed erbium-doped microsphere cavity with higher spherical by its surface tension when heating is stopped. The size of erbium-doped microsphere is 21μm. The position of erbium-doped microsphere is accurately adjusted between the pump power and monochromatic spectrometer so that it can be easily excited by 980 nm and 1480 nm infrared light. Excited erbium ions produce energy level transition and a number of sharp transmission spectrums are observed around the center wavelength of 1550nm. It expanded the spectrum wide and proved the frequency selection role of micro-cavity. Further analysis of the experimental results, we obtained the quality factor Q=4.4×108 through calculating the transmission spectrum which is consistent with the theoretical value largely.
采用CO2激光金属法加工掺铒锥形光纤的顶部,该光纤是通过拉伸标准光纤(SMF-125),同时用氢火焰加热而形成的。当停止加热时,锥形纤维顶部利用其表面张力形成了球形度更高的掺铒微球腔。掺铒微球尺寸为21μm。在泵浦功率和单色光谱仪之间精确调节掺铒微球的位置,使其易于被980 nm和1480 nm红外光激发。受激铒离子产生能级跃迁,在中心波长1550nm附近观察到许多清晰的透射光谱。扩大了频谱范围,证明了微腔的选频作用。进一步分析实验结果,通过计算透射谱得到的品质因子Q=4.4×108与理论值基本一致。
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引用次数: 2
Low-cost rapid prototyping of flexible plastic paper based microfluidic devices 基于柔性塑料纸的微流体装置的低成本快速成型
Yiqiang Fan, Huawei Li, Ying Yi, I. Foulds
This research presents a novel rapid prototyping method for paper-based flexible microfluidic devices. The microchannels were fabricated using laser ablation on a piece of plastic paper (permanent paper), the dimensions of the microchannels was carefully studied for various laser powers and scanning speeds. After laser ablation of the microchannels on the plastic paper, a transparent poly (methyl methacrylate)(PMMA) film was thermally bonded to the plastic paper to enclose the channels. After connection of tubing, the device was ready to use. An example microfluidic device (droplet generator) was also fabricated using this technique. Due to the flexibility of the fabricated device, this technique can be used to fabricate 3D microfluidic devices. The fabrication process was simple and rapid without any requirement of cleanroom facilities.
本研究提出了一种新型的纸基柔性微流体器件快速成型方法。采用激光烧蚀法在塑料纸(永久纸)上制备微通道,研究了不同激光功率和扫描速度下微通道的尺寸。激光烧蚀塑料纸上的微通道后,一层透明的聚甲基丙烯酸甲酯(PMMA)薄膜被热粘合在塑料纸上,以封闭通道。连接油管后,设备就可以使用了。并利用该技术制作了微流控装置(液滴发生器)的实例。由于所制备器件的灵活性,该技术可用于制备三维微流体器件。制备过程简单、快速,不需要任何洁净室设施。
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引用次数: 3
Three dimensional compensation spherical coils for compact atomic magnetometers 紧凑型原子磁力仪用三维补偿球形线圈
C. Zhuo, H. Dong, L. Xuan
To avoid the broadening of Zeeman resonances of the vector atomic magnetometer working in an unshielded environment, the rapid and accurate magnetic compensation is necessary. A three dimensional mini spherical compensating system is presented, which can be used together with a chip-scale atomic magnetometer to realize an ultra-high precision field measurement. Based on the field gradient method, parameters are optimized to obtain a uniformity of 10-3 over the region of one half radius with a good tolerance on dimensional variations. A prototype applied in the single laser beam scheme has been built and the experimental results demonstrate the validity of the design.
为了避免矢量原子磁强计在无屏蔽环境下工作时塞曼共振的展宽,需要对矢量原子磁强计进行快速准确的磁补偿。提出了一种三维微型球面补偿系统,该系统可与芯片级原子磁强计配合使用,实现超高精度的磁场测量。基于场梯度法对参数进行了优化,在半半径范围内得到了10-3的均匀性,对尺寸变化有良好的容错能力。建立了应用于单光束方案的原型机,实验结果证明了该设计的有效性。
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引用次数: 1
Close-loop self-compensation of the coupling error for silicon micromachined gyroscope 硅微机械陀螺仪耦合误差的闭环自补偿
Jianbin Su, D. Xiao, Xuezhong Wu, Zhihua Chen, Z. Hou
This paper presents the detailed analysis and preliminary design and experiment for close-loop self-compensation of the coupling error for silicon micromachined gyroscope. A closed-loop feedback control technology is adopted, which uses electrostatic force to counteract the change of coupling stiffness. The electrostatic force is generated by the detection variation of coupling error. Comparing with the open-loop detection, the experimental results indicated evidently that the proposed method can effectively decrease the value of the coupling error, increase its stability by 38 times, while the scale factor of the microgyroscope remains unchanged.
本文对硅微机械陀螺仪的耦合误差闭环自补偿进行了详细的分析、初步设计和实验。采用闭环反馈控制技术,利用静电力抵消耦合刚度的变化。静电力是由耦合误差的检测变化产生的。与开环检测相比,实验结果表明,该方法在保持微陀螺尺度因子不变的情况下,有效地降低了耦合误差值,稳定性提高了38倍。
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引用次数: 1
Superhydrophobic surface obtained using pyramidal PTFE film fabricated on RIE etched silicon 在RIE蚀刻硅上制备锥体聚四氟乙烯薄膜获得超疏水表面
C. Baek, Litao Yao, S. Seo, Hwa-Min Kim, D. Pyo, Pyo-Hwan Hong, Jung-Hwa Oh, D. Kong, Chanseob Cho, Jong-Hyun Lee, In-Yong Eom, Bonghwan Kim
We have developed a surface texturing process using a polytetrafluoroethylene coating with a pyramidal structure for obtaining superhydrophobic surfaces. In order to investigate the hydrophobic properties of the surface, we measured the contact angle and roughness values. The calculated roughness factor and root mean square roughness ranged from 2.47 to 2.6 and from 0.25 μm to 0.4 μm, respectively. The contact angle of a water droplet on the surface was greater than 150°; moreover, this angle was maintained for over 7 weeks. This observation implies that extremely low wettability is achievable on superhydrophobic surfaces.
我们开发了一种表面纹理工艺,使用具有锥体结构的聚四氟乙烯涂层来获得超疏水表面。为了研究表面的疏水性,我们测量了接触角和粗糙度值。计算得到的粗糙度系数和均方根粗糙度分别在2.47 ~ 2.6和0.25 ~ 0.4 μm之间。水滴与表面的接触角大于150°;而且,这个角度保持了7周以上。这一观察结果表明,在超疏水表面上可以实现极低的润湿性。
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引用次数: 1
Laser additive manufacturing technology in titanium 64 implant of microstructure fabrication and analysis 激光增材制造技术在钛64植入体中的微结构制备及分析
S. Lin, C. C. Lin, D. Lin, C. Chuang
Laser additive manufacturing technology is very attractive for industry applications due to the characterizations of rapid manufacture, flexible parameters select, customize, and complex 3D object fabricate. In this article, an EOS M-type direct metal laser sintering (DMLS) system was used to manufacture for customized hip implant with an IPG fiber laser. The part building process takes place inside an enclosed chamber filled with argon gas to minimize oxidation powdered material. We are successful design and producing an implant of imitation bone microstructure in titanium alloy. From the SEM analysis image, an approximately 100% dense surface has be observed. The mainly composition of selective laser additive manufacturing product are acicular structure of alpha-phase titanium. X-ray diffraction patterns also are observed the alpha-phase and beta-phase mixture. This customized hip implant is used to clinical application for replacement the golden retriever's femoral head, and it get good results. Imitation bone structure can promote the biocompatible of titanium material and bone.
激光增材制造技术具有制造速度快、参数选择灵活、可定制化、三维物体加工复杂等特点,在工业应用中具有很大的吸引力。本文采用EOS m型直接金属激光烧结(DMLS)系统,利用IPG光纤激光器制造定制髋关节假体。零件制造过程在一个充满氩气的封闭室中进行,以尽量减少氧化粉末材料。我们成功地设计并生产了一种仿骨微结构钛合金种植体。从SEM分析图像中,可以观察到大约100%的致密表面。选择性激光增材制造产品的主要成分是针状结构的α相钛。x射线衍射图也被观察到相和相混合物。该定制髋关节假体用于金毛猎犬股骨头置换术的临床应用,取得了良好的效果。仿骨结构可促进钛材料与骨的生物相容性。
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引用次数: 12
MEMS modeling of the Posterior Semicircular Canal for treating Benign Paroxysmal Positional Vertigo 后半规管MEMS模型治疗良性阵发性位置性眩晕
D. Kumar, Anomitra Banerjee, S. Swaminathan, Mustafa Mahesri
In this paper, we study the Posterior Semicircular Canal of the Peripheral Vestibular system containing moving Otoconia (Calcium Carbonate crystals) which leads to the condition of Benign Paroxysmal Positional Vertigo (BPPV). Using the governing equations of the affected semicircular canal we develop a novel MEMS device to mimic the pathophysiological condition wherein the kinocilia structure is modeled using PZT-2 micro-cantilever placed at various positions in the device to sense the position of the otoconia. The deflection produces a voltage of 0.416 mV indicating the proximity of the particles. Using this information we describe a functional block of this device that aids in treating BPPV via an audio assisted Canalith Repositioning Procedure (CRP).
在本文中,我们研究了周围前庭系统的后半规管,其中含有移动的耳石(碳酸钙晶体),导致良性阵发性位置性眩晕(BPPV)。利用受影响半规管的控制方程,我们开发了一种新的MEMS设备来模拟病理生理条件,其中使用放置在设备中不同位置的PZT-2微悬臂来模拟耳廓结构,以感知耳廓的位置。偏转产生0.416 mV的电压,表明粒子的接近。利用这些信息,我们描述了该装置的功能块,该装置通过音频辅助的管道重新定位程序(CRP)帮助治疗BPPV。
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引用次数: 1
Metal-catalyst free integration of SiO2 nanowires into carbon MEMS 二氧化硅纳米线在碳MEMS中的无金属催化剂集成
Liangliang Xu, T. Shi, S. Xi, Hu Long, Shiyuan Liu, Zirong Tang
This paper presents an innovative technique of integrating silica nanowires to photoresist-derived carbon microelectromechanical systems (C-MEMS) on silicon substrate. The silica nanowires were synthesized through thermal treatment in a tube furnace at 1200 °C under a gaseous environment of N2 and H2. The stiff morphology and radicalized distribution around carbon posts of nanowires was observed, which was different from much of the previous studies. High-temperature annealing and meticulous-controlled pyrolying atmosphere could be the causes of the formation of unusual SiO2/C-MEMS integrated structures.
提出了一种将二氧化硅纳米线集成到硅衬底光敏电阻衍生碳微机电系统(C-MEMS)的创新技术。在1200℃的管式炉中,在N2和H2气体环境下进行热处理,合成了二氧化硅纳米线。观察到纳米线碳柱周围的刚性形态和自由基分布,这与以往的许多研究不同。高温退火和精心控制的热解气氛可能是形成不同寻常的SiO2/C-MEMS集成结构的原因。
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引用次数: 0
期刊
The 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems
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