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Technical Digest. MEMS 2001. 14th IEEE International Conference on Micro Electro Mechanical Systems (Cat. No.01CH37090)最新文献

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In-line pressure monitoring for microfluidic devices using a deformable diffraction grating 利用可变形衍射光栅的微流体装置在线压力监测
K. Hosokawa, R. Maeda
In this paper, a novel optical method for monitoring of local pressure in a microfluidic device using a deformable diffraction grating is presented. A test device was fabricated with transparent silicone elastomer-polydimethylsiloxane (PDMS)-using the replica molding technique. A diffraction grating of 2 mm/spl times/2 mm area and a microchannel of 200 /spl mu/m width and 20 /spl mu/m depth are defined by the conformal contact between a PDMS chip and a glass plate. The grating consists of 5 /spl mu/m wide, 2 /spl mu/m deep rectangular grooves arrayed with period of 10 /spl mu/m, and it is connected to access ports with the microchannel. Optical response of the device to internal pressure ranging from 0 to -80 kPa is presented and compared with theoretical prediction. It is also demonstrated that the test device can be used for measurement of air flow rate ranging form 0 to 0.3 cc/min. The major advantages of this method are simple fabrication and flexible design. This method is not only desirable for flow characterization of microfluidic devices, but also opens up the possibility of new types of fiber-optic pressure sensors and pressure-driven optical modulators.
本文提出了一种利用可变形衍射光栅监测微流控器件局部压力的光学方法。以透明有机硅弹性体聚二甲基硅氧烷(PDMS)为材料,采用复模成型技术制备了试验装置。通过PDMS芯片与玻璃板的保角接触,定义了2 mm/spl × / 2mm面积的衍射光栅和200 /spl mu/m宽、20 /spl mu/m深的微通道。光栅由5 /spl mu/m宽、2 /spl mu/m深、周期为10 /spl mu/m的矩形沟槽组成,并与微通道接入口相连。给出了器件对0 ~ - 80kpa内压的光学响应,并与理论预测结果进行了比较。试验还表明,该测试装置可用于测量0 ~ 0.3 cc/min的空气流量。该方法的主要优点是制作简单,设计灵活。该方法不仅适用于微流控器件的流动表征,而且为新型光纤压力传感器和压力驱动光调制器的开发开辟了可能性。
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引用次数: 12
Flexible microelectrode arrays with integrated insertion devices 具有集成插入装置的柔性微电极阵列
D.P. O'Brien, T. Nichols, M. Allen
Flexible microelectrode arrays (FMAs) allow interfacing to delicate living tissues such as neural tissue with a minimum of physical disruption of that tissue during and after insertion. This physical disruption is minimized since the compliant FMAs can deform along with the tissue. However, a problem with these arrays is the insertion and subsequent precise positioning of the arrays in the tissue. Previous FMAs required hand assembly of the flexible array with another rigid structure. This may not be feasible if the dimensions of the flexible array are too small. In this work, FMAs with integrated rigid insertion devices were designed, fabricated, and assessed. Thin-film technology and electrodeposition were used to create flexible arrays with attached rigid insertion devices in a single sequence of fabrication steps. These arrays can be designed in two different configurations. The first type allows for flexible electrodes to be sewn through a nerve. The second allows for insertion into a surface such as the cerebral cortex or the spinal cord. After insertion, the rigid portion of the FMA is removed from the tissue with the flexible portion remaining behind. These two implantation schemes were tested on tissue models and found to be straightforward and reliable. In addition, comparisons of the potential to cause tissue damage between flexible and rigid arrays of similar dimensions were made under three different conditions of mechanical perturbation. In all cases, FMAs caused no damage to the tissue model above that caused by the original electrode insertion track while rigid arrays caused significant tearing. Finally, FMAs were shown to successfully stimulate neural tissue in an experimental setting.
柔性微电极阵列(fma)允许连接精致的活组织,如神经组织,在插入期间和之后对该组织的物理破坏最小。由于柔性fma可以随组织一起变形,因此这种物理破坏被最小化。然而,这些阵列的一个问题是阵列在组织中的插入和随后的精确定位。以前的fma需要用另一种刚性结构手工组装柔性阵列。如果柔性阵列的尺寸太小,这可能是不可行的。在这项工作中,设计,制造和评估了集成刚性插入装置的fma。利用薄膜技术和电沉积技术,在单一的制造步骤序列中创建了带有附加刚性插入器件的柔性阵列。这些阵列可以设计成两种不同的配置。第一种是将柔性电极缝入神经。第二种方法允许植入表面,如大脑皮层或脊髓。插入后,FMA的刚性部分从组织中取出,柔性部分留在后面。在组织模型上对这两种植入方案进行了测试,结果表明这两种方案简单可靠。此外,在三种不同的机械扰动条件下,比较了类似尺寸的柔性和刚性阵列对组织损伤的潜在影响。在所有情况下,fma对上述组织模型都没有造成原始电极插入轨迹造成的损伤,而刚性阵列则造成了明显的撕裂。最后,FMAs在实验环境中成功地刺激了神经组织。
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引用次数: 40
Electrostatically actuated gas microvalve based on a Ta-Si-N membrane 基于Ta-Si-N膜的静电驱动气体微阀
P. Dubois, B. Guldimann, M. Gretillat, N. D. de Rooij
An electrostatically actuated gas microvalve has been designed, fabricated and characterized. This valve is composed of a vertically moving, double-clamped Ta-Si-N membrane, located over a small (10 /spl mu/m), round orifice machined by deep reactive ion etching (DRIE) through the silicon substrate. The valve can be actuated as an on/off switch, or using pulse width modulation (PWM) to achieve a controlled flow rate. To our knowledge, previously reported, electrostatically actuated microvalves have had much larger orifices, which limited the operating pressures to less than 200 mbar, an order of magnitude lower than the valve presented. Furthermore, a controlled flow rate using PWM has never been demonstrated experimentally. The valve reported here thus represents the first working MEMS device integrating a sputtered Ta-Si-N layer, for use at differential pressures greater than 2 bar and capable of achieving controlled flow rates.
设计、制作了一种静电驱动气体微阀,并对其进行了表征。该阀由垂直移动的双夹紧Ta-Si-N膜组成,位于通过硅衬底的深反应离子蚀刻(DRIE)加工的小(10 /spl mu/m)圆形孔上。该阀可以作为开/关开关来驱动,或使用脉宽调制(PWM)来实现控制流量。据我们所知,之前有报道称,静电驱动的微阀具有更大的孔口,将操作压力限制在200毫巴以下,比目前的阀门低一个数量级。此外,使用PWM控制流量从未被实验证明。因此,这里报道的阀门代表了第一个集成溅射Ta-Si-N层的工作MEMS器件,用于大于2 bar的压差,并能够实现可控的流量。
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引用次数: 21
In-chip cell-free protein synthesis from DNA by using biochemical IC chips 利用生物化学集成电路芯片从DNA合成片内无细胞蛋白
K. Ikuta, A. Takahashi, S. Maruo
World's first "In-chip cell-free protein synthesis from DNA" in the biochemical IC chips was demonstrated. A luminous protein of firefly "Luciferase" was synthesized from DNA and monitored in real time manner. This micro chemical laboratory was constructed by prefabricated biochemical IC chips proposed and developed by the authors. Each chip was three dimensionally fabricated by using "Hybrid micro stereolithography". Our successful results provide new and strong method demanded from post-genome research to find the relationship between gene and protein. User assemble versatile biochemical IC chips provide us to reduces experimental through put time, the cost of expensive biochemical reagent and apparatus for various kinds of protein. DNA originated cell-free protein synthesis is one of the biggest key technology for not only life science but also medicine and drug discovery.
展示了世界上第一个“芯片内无细胞DNA合成蛋白质”的生化集成电路芯片。利用荧光素酶(Luciferase)合成了萤火虫发光蛋白,并对其进行了实时监测。该微化学实验室是由作者提出并研制的预制生化IC芯片构建而成。每个芯片都采用“混合微立体光刻”技术进行三维制作。我们的研究成果为后基因组研究寻找基因与蛋白质之间的关系提供了新的有力方法。用户组装多功能生化IC芯片为我们减少各种蛋白质的实验时间、昂贵的生化试剂和仪器的成本。DNA来源的无细胞蛋白质合成不仅是生命科学的关键技术之一,也是医学和药物发现的关键技术之一。
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引用次数: 16
A micro ER valve fabricated by micromachining 微机械加工制备的微型电磁阀
K. Yoshida, M. Kikuchi, Jung-Ho Park, S. Yokota
As an advanced control component for practical micromachines using fluid power in millimeter size, the authors have proposed a micro ER valve using homogeneous ER fluids and verified the validity through basic experiments using several micro ER valves fabricated by conventional machining. In this paper, to control micro grippers mounted on micromachines, further miniaturized ER valves are realized by using micromachining. Firstly, to investigate an ER effect in micro size, several 2-port micro ER valves with different electrode gap lengths are fabricated and investigated. It is ascertained that the viscosity change rate is 4.5 constant with miniaturization. Secondly, a 3-port micro ER valve is fabricated and basic characteristics are experimentally investigated. It is ascertained that the controllable pressure change rate is 60% of supply pressure and the rise time is 0.2 s. Finally, the validity of the micro ER valve is confirmed by applying to position control of a bellows microactuator.
作为一种先进的毫米级流体动力微机械控制元件,作者提出了一种采用均质内质流体的微内质阀,并通过几个常规加工的微内质阀的基础实验验证了其有效性。为了控制安装在微机械上的微夹持器,本文采用微加工技术实现了电磁阀的进一步小型化。首先,为了研究微尺度下的电流变换器效应,制作并研究了几个具有不同电极间隙长度的2端口微型电流变换器阀。随着微型化,确定了粘度变化率为4.5常数。其次,制作了一种3孔微型电磁阀,并对其基本特性进行了实验研究。确定了可控压力变化率为供给压力的60%,上升时间为0.2 s。最后,通过应用于波纹管微执行器的位置控制,验证了微型电磁阀的有效性。
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引用次数: 6
Fabrication of microprobe array with sub-100 nm nano-heater for nanometric thermal imaging and data storage 用于纳米热成像和数据存储的亚100nm纳米加热器微探针阵列的制备
Dongwan Lee, T. Ono, T. Abe, M. Esashi
A novel fabrication method of a micro-thermal probe and its array for nanometric thermal imaging and a technological approach for probe-based data storage are presented. A small metal wire for a nano-heater is fabricated at the apex of a pyramidal SiO/sub 2/ tip, which is formed by low temperature oxidation of a silicon etch-pit at 950/spl deg/C, consecutive metal deposition (Pt/Cr or Au/Cr) to fill the metal into the etch-pit, and etching of the SiO/sub 2/ in buffered HF solution. Another metal (Ni) is deposited on the small wire to form a metal-to-metal junction that enables to measure the temperature at the tip end. Metal feed-through are formed on a glass substrate that is bonded with the probe array, which enables to transmit a high-speed signal to a processing-circuit and increase the probe array density. Using the thermal probe, temperature distribution on a sample surface is measured. The heating capability of nano-heater is confirmed by the resistivity change and thermophoton emission from the nano-heater when flowing a small current into the nano-heater. By using a micro-probe, preliminary experiment for data writing and erasing is performed on phase change medium.
提出了一种用于纳米热成像的微热探头及其阵列的新型制作方法和基于探头的数据存储技术途径。采用950℃低温氧化硅蚀刻坑,连续沉积金属(Pt/Cr或Au/Cr)填充到蚀刻坑中,并在缓冲HF溶液中蚀刻SiO/sub - 2/,在SiO/sub - 2/锥形尖端的顶端制作了用于纳米加热器的小金属丝。另一种金属(Ni)沉积在小导线上,形成金属对金属结,可以测量尖端的温度。在与探头阵列结合的玻璃基板上形成金属馈线,使高速信号传输到处理电路并增加探头阵列密度。利用热探针,测量样品表面的温度分布。通过对纳米加热器进行小电流输入时,其电阻率变化和热光子发射来证实纳米加热器的加热能力。利用微探针对相变介质进行了数据写入和擦除的初步实验。
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引用次数: 22
High density electrical feedthrough fabricated by deep reactive ion etching of Pyrex glass 高温玻璃深层反应离子刻蚀制备高密度电馈通
Xiaghua Li, T. Abe, Yongxun Liu, M. Esashi
This paper reports a new fabrication technology of Pyrex glass with a fine pitch electrical feedthrough. Small through holes (40-60 /spl mu/m in diameter) in Pyrex glass plate have been fabricated using deep reactive ion etching in sulfur hexafluoride (SF/sub 6/) plasma. By filling the through holes with electroplated metal, the fine pitch electrical feedthrough in Pyrex glass plate becomes enable technology. Pyrex glass can be anodically bonded with silicon. Thus, our technology will be widely used for high density electrical feedthrough to the backside of a plate. The applications of the technology to micro probe array used for high density data storage and packaged devices are expected.
本文报道了一种采用细间距电馈通法制备耐热玻璃的新工艺。在六氟化硫(SF/sub 6/)等离子体中,采用深度反应离子刻蚀技术,在Pyrex玻璃板上制备了直径为40 ~ 60 μ l μ m的小通孔。通过在通孔中填充电镀金属,使热玻璃板的细间距电馈通成为一项可行的技术。耐热玻璃可以与硅阳极结合。因此,我们的技术将广泛应用于高密度电馈通到板的背面。该技术在高密度数据存储和封装器件微探针阵列中的应用前景十分广阔。
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引用次数: 29
An electrostatic induction micromotor supported on gas-lubricated bearings 由气体润滑轴承支撑的静电感应微型电动机
Luc G. Fréchette, Steve Nagle, R. Ghodssi, S. Umans, Martin A. Schmidt, Jeffrey H. Lang
This paper reports the first successful fabrication and demonstration of an electrostatic induction micromotor supported on gas-lubricated bearings for electrical-to-mechanical energy conversion. The device consists of a stack of five (5) deep reactive ion etched (DRIE) fusion bonded silicon wafers, with an enclosed 4.2 mm diameter rotor driven by a high-voltage, high-frequency thin-film stator. Testing has demonstrated a torque of 0.3 /spl mu/Nm at a rotation rate of 15,000 revolutions per minute, corresponding to a shaft power of 0.5 mW. This development effort serves to support the creation of a wide array of power MEMS devices such as micro-scale pumps, compressors, generators, and coolers.
本文报道了一种基于气体润滑轴承的静电感应微型电机的首次成功制造和演示,用于电-机械能转换。该器件由五(5)片深度反应离子蚀刻(DRIE)融合硅片堆叠而成,带有一个由高压高频薄膜定子驱动的直径4.2 mm的封闭式转子。测试表明,在每分钟15,000转的转速下,扭矩为0.3 /spl mu/Nm,对应的轴功率为0.5 mW。这项开发工作有助于支持创建各种功率MEMS器件,如微型泵,压缩机,发电机和冷却器。
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引用次数: 82
Optically-driven actuator using photo-induced phase-transition material 采用光致相变材料的光驱动驱动器
T. Ikehara, M. Tanaki, S. Shimada, H. Matsuda
The authors propose a new optically driven actuator which utilizes photo-induced phase-transition (PIPT) material. This actuator is expected to be useful for micromechanical systems, since it provides a wireless energy supply by light. In these PIPT materials the material phase is changed by irradiation of light, as well as by temperature or external fields. In this report, a kind of polydiacetylene (PDA) substituted with alkyl-urethane is investigated. This material is known to exhibit reversible PIPT around 125/spl deg/C between the 'blue' phase and 'red' phase. The authors measured the induced macroscopic elongation of PDA crystal using a displacement meter. The induced strains due to thermal phase transition were measured to be 2%, 0.03%, and 0.9% at 125/spl deg/C for the a-, b-, and c-axes, respectively. These values are larger than that of the piezoelectric or thermal-expansion materials conventionally used for microactuators. Material deformation due to light-pulse irradiation was demonstrated for the first time. The observed bending was explained by bimorph formation induced by phase transition at the irradiated surface.
提出了一种利用光致相变(PIPT)材料的新型光驱动驱动器。这种驱动器有望用于微机械系统,因为它通过光提供无线能量供应。在这些PIPT材料中,材料相位通过光的照射以及温度或外部场而改变。本文研究了一种以烷基脲烷取代的聚二乙炔(PDA)。已知这种材料在“蓝”相和“红”相之间表现出125/spl℃左右的可逆PIPT。用位移计测量了PDA晶体的诱导宏观伸长。在125/spl℃下,a轴、b轴和C轴的热相变诱导菌株分别为2%、0.03%和0.9%。这些值比通常用于微致动器的压电或热膨胀材料的值大。首次证明了光脉冲辐照引起的材料变形。观察到的弯曲可以用辐照表面相变引起的双晶形成来解释。
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引用次数: 8
Localized plastic bonding for micro assembly, packaging and liquid encapsulation 用于微组装、包装和液体封装的本地化塑料粘接
Yu-Chuan Su, Liwei Lin
Localized plastic bonding schemes for plastics-to-silicon, plastics-to-glass, and plastics-to-plastics assembly, packaging and liquid encapsulation have been successfully demonstrated. Aluminum thin films are deposited and patterned as resistive heaters for the purpose of localized heating and bonding. In the experiments, plastic thin films are successfully bonded on silicon, glass, and plastic substrates in 0.25 seconds under a contact pressure of 0.4 MPa. Local temperature at the bonding interface can reach more than 140/spl deg/C for bonding and the global substrate remains at room temperature. The approach of localized heating for bonding of plastic materials while maintaining low temperature globally enables direct sealing of polymer based MEMS processing without using additional adhesive and without damaging pre-existing, temperature-sensitive substances on the bonding substrate. Water encapsulation by plastics-to-plastics bonding is performed to demonstrate the capability of low temperature processing. As such, this technique can be applied broadly in plastic assembly, packaging and liquid encapsulation for microsystems, including microfluidic devices.
已经成功演示了塑料与硅、塑料与玻璃、塑料与塑料组装、包装和液体封装的本地化塑料粘合方案。铝薄膜的沉积和图案化作为电阻加热器的目的是局部加热和键合。在实验中,在0.4 MPa的接触压力下,塑料薄膜在0.25秒内成功地粘合在硅、玻璃和塑料基板上。结合界面的局部温度可达到140℃以上,整体基底保持室温。在保持整体低温的同时,局部加热塑料材料粘合的方法可以直接密封基于聚合物的MEMS加工,而无需使用额外的粘合剂,也不会损坏粘合基板上已有的温度敏感物质。通过塑料与塑料的粘合进行水封装,以证明低温处理的能力。因此,该技术可以广泛应用于包括微流体装置在内的微系统的塑料组装、包装和液体封装。
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引用次数: 25
期刊
Technical Digest. MEMS 2001. 14th IEEE International Conference on Micro Electro Mechanical Systems (Cat. No.01CH37090)
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