Pub Date : 2019-12-01DOI: 10.24815/jks.v19i3.17974
Y. Sutanto, M. Sutanto, Hendra - Kurniawan
Background: Harmful particles from cigarette smoke induces an inflammatory immune response in the lungs, followed by the release of proinflammatory cytokines such as TNF-α and IL-8 and damages histone deacetylase 2 (HDAC2) in the cell core leading to glucocorticoid resistance in COPD. Low dose Theophylline of below 10mg/L has an anti-inflammatory effect by activating HDAC. This study aimed to analyze the effect of low dose theophylline on the clinical improvement of stable COPD patients assessed by the COPD Assessment Test (CAT) score, IL-8 level, and sputum neutrophil count.Methods: We conducted a quasi-experimental clinical study using a pre-post test in stable COPD patients visiting the Pulmonary Outpatient Clinic of DR. Moewardi hospital Surakarta, between July and September 2016. The samples were taken using a consecutive sampling technique, assigned into two groups, treatment, receiving standard therapy plus 70 mg low dose theophylline per 8 hours, and control receiving standard therapy only. CAT score, IL-8 level, and sputum neutrophil count were measured at baseline and four weeks after treatment.Results: The treatment group's CAT score decreased by 3.67±3.58 pg/ml and increased by 2.40±3.38 pg/ml in the control group (p=0.003). IL-8 level decreased by 4.31±13.06 pg/ml in the treatment group and increased by 0.88±13.89 pg/ml in the control group (p=0.116). The sputum neutrophil count decreased in both treatment and control groups by 4.00 ±40.33 pg/ml and 2. 87±39. 91 pg/ml (p=0.939).Conclusion: Statistically low dose theophylline significantly lowers the CAT score of stable COPD patients. It also decreases IL-8 level and sputum neutrophil count, although it is not significant.
{"title":"The effect of low dose teophillyne on the improvement of copd assessment test score, interleukin-8 level and sputum neutrophil count in patients with stable COPD","authors":"Y. Sutanto, M. Sutanto, Hendra - Kurniawan","doi":"10.24815/jks.v19i3.17974","DOIUrl":"https://doi.org/10.24815/jks.v19i3.17974","url":null,"abstract":"Background: Harmful particles from cigarette smoke induces an inflammatory immune response in the lungs, followed by the release of proinflammatory cytokines such as TNF-α and IL-8 and damages histone deacetylase 2 (HDAC2) in the cell core leading to glucocorticoid resistance in COPD. Low dose Theophylline of below 10mg/L has an anti-inflammatory effect by activating HDAC. This study aimed to analyze the effect of low dose theophylline on the clinical improvement of stable COPD patients assessed by the COPD Assessment Test (CAT) score, IL-8 level, and sputum neutrophil count.Methods: We conducted a quasi-experimental clinical study using a pre-post test in stable COPD patients visiting the Pulmonary Outpatient Clinic of DR. Moewardi hospital Surakarta, between July and September 2016. The samples were taken using a consecutive sampling technique, assigned into two groups, treatment, receiving standard therapy plus 70 mg low dose theophylline per 8 hours, and control receiving standard therapy only. CAT score, IL-8 level, and sputum neutrophil count were measured at baseline and four weeks after treatment.Results: The treatment group's CAT score decreased by 3.67±3.58 pg/ml and increased by 2.40±3.38 pg/ml in the control group (p=0.003). IL-8 level decreased by 4.31±13.06 pg/ml in the treatment group and increased by 0.88±13.89 pg/ml in the control group (p=0.116). The sputum neutrophil count decreased in both treatment and control groups by 4.00 ±40.33 pg/ml and 2. 87±39. 91 pg/ml (p=0.939).Conclusion: Statistically low dose theophylline significantly lowers the CAT score of stable COPD patients. It also decreases IL-8 level and sputum neutrophil count, although it is not significant.","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84042639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-01DOI: 10.24815/JKS.V19I2.18057
Birgitta Vania Rarasati
Abstract. Background: Gedi plant (Abelmoschus manihot (L.) Medik) of the Malvaceae family is a plant which leaf is used by peoples for the treatment of several illnesses such as constipation. Purpose: To investigate the laxative activity of green gedi leaves infuses (Abelmoschus manihot (L.) Medik) on male white mice.Method: This study is an experimental study. Mice were divided in 5 groups of 6 animals each, first group as negative control (CMC Na 0.5%) while group 2, 3 and 4 were treated with green gedi leaves infuses (Abelmoschus manihot (L.) Medik) at doses of 130, 260 and 520 mg/kgBW, per as respectively and group 5 as positive control (bisacodyl). The laxative activity was determined based on the frequency of defecation, weight of feces and consistency of feces.Results: It is found that 520 mg/kgBW dose has the highest mean of defecating frequency (7.17) and 260 mg/kgBW dose has the highest mean of feces weight (0.20). Statically however, there is no significant difference between the groups overall with p value of 0.132 and 0.246 for defecating frequency and feces weight respectively. There is no difference between the groups in term of feces consistency with both not defecating and hard feces.Conclusion: The research concludes that there is no significant laxative activity between each groups after administration of several dosages in 6 hours on mice thus the use of green gedi leaves as laxative in society can not be proven empirically in the laboratory.Keywords: gedi leaf, Abelmoschus manihot (L.) Medik, laxative effect, constipation
摘要背景:格地植物(Abelmoschus manihot (L.))锦葵科的锦葵是一种植物，它的叶子被人们用来治疗便秘等几种疾病。目的:研究绿葛地叶冲剂的通便作用。在雄性白鼠身上。方法:本研究为实验研究。将小鼠分为5组，每组6只，第一组为阴性对照(CMC Na 0.5%)，第2、3、4组灌胃绿葛地叶(Abelmoschus manhot, L.)。Medik)剂量分别为130、260和520 mg/kgBW，第5组为阳性对照(bisacodyl)。根据排便次数、粪便重量和粪便粘稠度测定通便活性。结果:520 mg/kgBW剂量的平均排便次数最高(7.17次)，260 mg/kgBW剂量的平均排便重量最高(0.20次)。但总体上各组间无显著差异，排便次数和粪便重的p值分别为0.132和0.246。在粪便一致性方面，两组之间没有差异，不排便和硬粪便。结论:本研究认为，在6小时内多次给药后，各组之间没有明显的通便作用，因此绿葛地叶在社会上的通便作用还不能在实验室得到实证证明。关键词:葛地叶，马氏白毛鼠本品有通便、通便作用
{"title":"LAXATIVE EFFECT OF GREEN GEDI LEAVES INFUSES (Abelmoschus manihot (L.) Medik) ON MALE WHITE MICE (Mus musculus)","authors":"Birgitta Vania Rarasati","doi":"10.24815/JKS.V19I2.18057","DOIUrl":"https://doi.org/10.24815/JKS.V19I2.18057","url":null,"abstract":"Abstract. Background: Gedi plant (Abelmoschus manihot (L.) Medik) of the Malvaceae family is a plant which leaf is used by peoples for the treatment of several illnesses such as constipation. Purpose: To investigate the laxative activity of green gedi leaves infuses (Abelmoschus manihot (L.) Medik) on male white mice.Method: This study is an experimental study. Mice were divided in 5 groups of 6 animals each, first group as negative control (CMC Na 0.5%) while group 2, 3 and 4 were treated with green gedi leaves infuses (Abelmoschus manihot (L.) Medik) at doses of 130, 260 and 520 mg/kgBW, per as respectively and group 5 as positive control (bisacodyl). The laxative activity was determined based on the frequency of defecation, weight of feces and consistency of feces.Results: It is found that 520 mg/kgBW dose has the highest mean of defecating frequency (7.17) and 260 mg/kgBW dose has the highest mean of feces weight (0.20). Statically however, there is no significant difference between the groups overall with p value of 0.132 and 0.246 for defecating frequency and feces weight respectively. There is no difference between the groups in term of feces consistency with both not defecating and hard feces.Conclusion: The research concludes that there is no significant laxative activity between each groups after administration of several dosages in 6 hours on mice thus the use of green gedi leaves as laxative in society can not be proven empirically in the laboratory.Keywords: gedi leaf, Abelmoschus manihot (L.) Medik, laxative effect, constipation","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88158240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-01DOI: 10.24815/jks.v19i2.18063
Ni Putu Anggita Medyantari, S. Soedarsono, M. Wahyunitisari
Abstract. Multi-drug resistance is a condition where drugs rifampicin and isoniazid is not effective in killing bacteria Mycobacterium tuberculosis. Some of the causes of resistance to OAT are the use of a single drug in the treatment of tuberculosis, the use of drugs is inadequate and the irregular drug administration. In RSUD Dr. Soetomo, 25% of MDR Pulmonary TB patients do not want to be treated because symptoms are mild, no pain and feel the treatment is not comparable with the symptoms. This research is to determine the correlation between sex, age, nutritional status and diabetes mellitus with the clinical description of MDR pulmonary TB patients in RSUD Dr. Soetomo. Hence, it is expected people can make the earliest possible prevention against this disease. In addition, clinicians are more aware of the symptoms of MDR Pulmonary TB. Method in this research is descriptive observational study research. There were 103 patients taken as the sample of the study. Research variables consist of sex, age, nutritional status, and diabetes mellitus. The obtained data were analyzed by administering Chi- square analysis. The results of this study showed that each variable tested in this study (sex, age, nutritional status and diabetes mellitus) associated with the symptoms of MDR Pulmonary TB has p 0.05 which means no significant relationship. There are no relation between sex, age, nutrition status and comorbidities with symptom of MDR pulmonary TB. Keywords: multidrug resistance, sex, age, nutritional status, diabetes mellitus Multi-drug resistance adalah suatu kondisi dimana obat rifampisin dan isoniazid tidak efektif dalam membunuh bakteri Mycobacterium tuberculosis. Beberapa penyebab resistensi terhadap OAT adalah penggunaan obat tunggal dalam pengobatan tuberkulosis, penggunaan obat tidak memadai dan pemberian obat tidak teratur. Di RSUD Dr. Soetomo, 25% pasien TB paru MDR tidak mau diobati karena gejalanya ringan, tidak terasa sakit dan rasakan pengobatannya tidak sebanding dengan gejalanya. Penelitian ini bertujuan untuk mengetahui hubungan antara jenis kelamin, umur, status gizi dan diabetes mellitus dengan gambaran klinis pasien TB paru MDR di RSUD Dr. Soetomo. Sehingga diharapkan masyarakat bisa melakukan pencegahan paling dini terhadap penyakit ini. Selain itu, dokter lebih sadar akan gejala TB paru MDR. Metode yang digunakan dalam penelitian ini adalah penelitian observasional deskriptif. Terdapat 103 pasien yang diambil sebagai sampel penelitian. Variabel penelitian terdiri dari jenis kelamin, umur, status gizi, dan diabetes mellitus. Data yang diperoleh dianalisis dengan analisis Chi-square. Hasil penelitian ini menunjukkan bahwa setiap variabel yang diuji (jenis kelamin, usia, status gizi dan diabetes mellitus) yang dihubungkan dengan gejala TB paru MDR memiliki p 0,05 yang berarti tidak ada hubungan yang signifikan. Kesimpulannya, tidak ada hubungan antara jenis kelamin, usia, status gizi dan komorbiditas dengan gejala TB paru MD
摘要多重耐药是指药物利福平和异烟肼不能有效杀死结核分枝杆菌的情况。OAT耐药的一些原因是在治疗结核病时使用单一药物、药物使用不足和药物给药不规律。在RSUD Soetomo博士中，25%的耐多药肺结核患者不想接受治疗，因为症状轻微，没有疼痛，并且觉得治疗与症状不具有可比性。本研究旨在确定性别、年龄、营养状况和糖尿病与RSUD中耐多药肺结核患者临床描述的相关性。因此，人们可以尽早预防这种疾病。此外，临床医生也更加了解耐多药肺结核的症状。本研究方法为描述性观察性研究。本研究共选取103例患者作为研究样本。研究变量包括性别、年龄、营养状况和糖尿病。所得资料进行卡方分析。本研究结果显示，本研究检测的各变量(性别、年龄、营养状况和糖尿病)与耐多药肺结核症状相关的p < 0.05，即无显著相关性。性别、年龄、营养状况与耐多药肺结核合并症症状无相关性。关键词:多重耐药，性别，年龄，营养状况，糖尿病多重耐药阿达拉素，利福平，异烟肼，利福平，巴氏杆菌，结核分枝杆菌彭家南结核，彭家南结核，彭家南结核，彭家南结核，彭家南结核，彭家南结核，彭家南结核。Di RSUD Dr. Soetomo, 25%患者结核病paru MDR tidak mau diobati karena gejalanya ringan, tidak terasa sakit dan rasakan pengobatannya tidak sebanding dengan gejalanya。Penelitian ini bertujuan untuk mengetahui hubungan antara jenis kelamin, umur, status gizi dan糖尿病dengan gambaran klinis pasen TB paru MDR di RSUD Soetomo博士。sehinga diharapkan masyarakat bisa melakukan penegahan paling dini terhadap penyakit ini。Selain itu, dr . lebih sadar . akan . gejala TB paru MDR。Metode yang digunakan dalam penelitian ini adalah penelitian观测描述。[3][1][1][1][1][1][1][1]。变量penelitian terdiri dari jenis kelamin, umur, status gizi, dan糖尿病。数据阳斜分析，登甘分析，卡方分析。杨氏病(jenis kelamin, usia, status gizi dan diabetes);杨氏病(TB paru MDR memiliilij, 2005);杨氏病(dr);结核病耐多药(TB paru MDR)。
{"title":"THE CORRELATION BETWEEN SEX, AGE, NUTRITIONAL STATUS AND DIABETES MELLITUS WITH CLINICAL SYMPTOMS MDR PULMONARY TB AT RSUD DR SOETOMO","authors":"Ni Putu Anggita Medyantari, S. Soedarsono, M. Wahyunitisari","doi":"10.24815/jks.v19i2.18063","DOIUrl":"https://doi.org/10.24815/jks.v19i2.18063","url":null,"abstract":"Abstract. Multi-drug resistance is a condition where drugs rifampicin and isoniazid is not effective in killing bacteria Mycobacterium tuberculosis. Some of the causes of resistance to OAT are the use of a single drug in the treatment of tuberculosis, the use of drugs is inadequate and the irregular drug administration. In RSUD Dr. Soetomo, 25% of MDR Pulmonary TB patients do not want to be treated because symptoms are mild, no pain and feel the treatment is not comparable with the symptoms. This research is to determine the correlation between sex, age, nutritional status and diabetes mellitus with the clinical description of MDR pulmonary TB patients in RSUD Dr. Soetomo. Hence, it is expected people can make the earliest possible prevention against this disease. In addition, clinicians are more aware of the symptoms of MDR Pulmonary TB. Method in this research is descriptive observational study research. There were 103 patients taken as the sample of the study. Research variables consist of sex, age, nutritional status, and diabetes mellitus. The obtained data were analyzed by administering Chi- square analysis. The results of this study showed that each variable tested in this study (sex, age, nutritional status and diabetes mellitus) associated with the symptoms of MDR Pulmonary TB has p 0.05 which means no significant relationship. There are no relation between sex, age, nutrition status and comorbidities with symptom of MDR pulmonary TB. Keywords: multidrug resistance, sex, age, nutritional status, diabetes mellitus Multi-drug resistance adalah suatu kondisi dimana obat rifampisin dan isoniazid tidak efektif dalam membunuh bakteri Mycobacterium tuberculosis. Beberapa penyebab resistensi terhadap OAT adalah penggunaan obat tunggal dalam pengobatan tuberkulosis, penggunaan obat tidak memadai dan pemberian obat tidak teratur. Di RSUD Dr. Soetomo, 25% pasien TB paru MDR tidak mau diobati karena gejalanya ringan, tidak terasa sakit dan rasakan pengobatannya tidak sebanding dengan gejalanya. Penelitian ini bertujuan untuk mengetahui hubungan antara jenis kelamin, umur, status gizi dan diabetes mellitus dengan gambaran klinis pasien TB paru MDR di RSUD Dr. Soetomo. Sehingga diharapkan masyarakat bisa melakukan pencegahan paling dini terhadap penyakit ini. Selain itu, dokter lebih sadar akan gejala TB paru MDR. Metode yang digunakan dalam penelitian ini adalah penelitian observasional deskriptif. Terdapat 103 pasien yang diambil sebagai sampel penelitian. Variabel penelitian terdiri dari jenis kelamin, umur, status gizi, dan diabetes mellitus. Data yang diperoleh dianalisis dengan analisis Chi-square. Hasil penelitian ini menunjukkan bahwa setiap variabel yang diuji (jenis kelamin, usia, status gizi dan diabetes mellitus) yang dihubungkan dengan gejala TB paru MDR memiliki p 0,05 yang berarti tidak ada hubungan yang signifikan. Kesimpulannya, tidak ada hubungan antara jenis kelamin, usia, status gizi dan komorbiditas dengan gejala TB paru MD","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89906587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract. Stomach pain (dysmenorrhea) is abdominal cramps and pain during the menstrual period which can interfere with the daily activities of women of reproductive age. Dysmenorrhea is one of the symptoms that needs to be considered because it is often experienced by women and is an early sign of suffering from endometriosis. The presence of abdominal pain in women during menstruation, accompanied by pelvic pain, and infertility is a classic trias of symptoms used to diagnose endometriosis. Endometriosis occurs in almost 10% of women in the reproductive age period and more than 25-40% in infertile women. The risk of infertility is also linked because inflamed endometriosis tissue damages sperm and egg cells. Some treatments that can be done for patients with endometriosis are medical and surgical therapy. If medical therapy fails, operative laparoscopy can be alternative and hysterectomy can be considered for patients who no longer expect their reproductive function. Keywords: abdominal pain, endometriosis, infertility, dysmenorrhea. Abstrak. Nyeri Perut (dismenore) merupakan kram perut dan nyeri selama periode menstruasi yang dapat mengganggu aktivitas sehari-hari wanita usia reproduksi. Dismenore merupakan salah satu gejala yang perlu dipertimbangkan karena kerap dialami wanita dan menjadi tanda awal menderita endometriosis. Adanya nyeri perut pada wanita saat haid, disertai nyeri panggul, dan infertilitas merupakan trias klasik gejala yang digunakan untuk mendiagnosis endometriosis. Endometriosis terjadi pada hampir 10% wanita dalam kurun usia reproduksi dan lebih dari 25-40% pada wanita infertil (mandul). Risiko mandul juga dikaitkan karena jaringan endometriosis yang meradang merusak sperma dan sel telur. Beberapa pengobatan yang dapat dilakukan pada penderita endometriosis adalah terapi medikamentosa dan pembedahan. Jika terapi medikamentosa gagal, laparoskopi operatif dapat menjadi altenatif dan histerektomi dapat dipertimbangkan pada pasien yang tidak mengharapkan fungsi reproduksi lagi. Kata Kunci: nyeri perut, endometriosis, infertilitas, dismenore.
摘要胃痛(痛经)是月经期间腹部痉挛和疼痛，会干扰育龄妇女的日常活动。痛经是需要考虑的症状之一，因为它经常发生在女性身上，是子宫内膜异位症的早期征兆。女性在月经期间腹痛，伴有盆腔疼痛和不孕症是诊断子宫内膜异位症的典型症状。子宫内膜异位症发生在近10%的育龄妇女中，超过25-40%发生在不育妇女中。不孕的风险也与此有关，因为发炎的子宫内膜异位症组织会损害精子和卵细胞。子宫内膜异位症的一些治疗方法包括药物治疗和手术治疗。如果药物治疗失败，可以选择腹腔镜手术，对于不再期望生育功能的患者可以考虑子宫切除术。关键词:腹痛，子宫内膜异位症，不孕症，痛经。Abstrak。Nyeri Perut(更年期)merupakan kram Perut dan Nyeri selama period menstrual，月经期，月经期子宫内膜异位症，子宫内膜异位症，子宫内膜异位症子宫内膜异位症，子宫内膜异位症，子宫内膜异位症，子宫内膜异位症子宫内膜异位症:子宫内膜异位症，子宫内膜异位症，子宫内膜异位症，子宫内膜异位症，子宫内膜异位症，子宫内膜异位症，子宫内膜异位症，子宫内膜异位症，子宫内膜异位症，子宫内膜异位症，子宫内膜异位症，子宫内膜异位症，子宫内膜异位症子宫内膜异位症，子宫内膜异位症，子宫内膜异位症。子宫内膜异位症，子宫内膜异位症，子宫内膜异位症，子宫内膜异位症。腹腔镜手术，腹腔镜手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术，输卵管手术。Kata Kunci:子宫内膜异位症，不孕症，痴呆。
{"title":"NYERI PERUT BERULANG SAAT HAID, BERISIKO MANDUL?","authors":"Mohd. Andalas, Cut Rika Maharani, Rayhan Shafithri","doi":"10.24815/jks.v19i2.18066","DOIUrl":"https://doi.org/10.24815/jks.v19i2.18066","url":null,"abstract":"Abstract. Stomach pain (dysmenorrhea) is abdominal cramps and pain during the menstrual period which can interfere with the daily activities of women of reproductive age. Dysmenorrhea is one of the symptoms that needs to be considered because it is often experienced by women and is an early sign of suffering from endometriosis. The presence of abdominal pain in women during menstruation, accompanied by pelvic pain, and infertility is a classic trias of symptoms used to diagnose endometriosis. Endometriosis occurs in almost 10% of women in the reproductive age period and more than 25-40% in infertile women. The risk of infertility is also linked because inflamed endometriosis tissue damages sperm and egg cells. Some treatments that can be done for patients with endometriosis are medical and surgical therapy. If medical therapy fails, operative laparoscopy can be alternative and hysterectomy can be considered for patients who no longer expect their reproductive function. Keywords: abdominal pain, endometriosis, infertility, dysmenorrhea. Abstrak. Nyeri Perut (dismenore) merupakan kram perut dan nyeri selama periode menstruasi yang dapat mengganggu aktivitas sehari-hari wanita usia reproduksi. Dismenore merupakan salah satu gejala yang perlu dipertimbangkan karena kerap dialami wanita dan menjadi tanda awal menderita endometriosis. Adanya nyeri perut pada wanita saat haid, disertai nyeri panggul, dan infertilitas merupakan trias klasik gejala yang digunakan untuk mendiagnosis endometriosis. Endometriosis terjadi pada hampir 10% wanita dalam kurun usia reproduksi dan lebih dari 25-40% pada wanita infertil (mandul). Risiko mandul juga dikaitkan karena jaringan endometriosis yang meradang merusak sperma dan sel telur. Beberapa pengobatan yang dapat dilakukan pada penderita endometriosis adalah terapi medikamentosa dan pembedahan. Jika terapi medikamentosa gagal, laparoskopi operatif dapat menjadi altenatif dan histerektomi dapat dipertimbangkan pada pasien yang tidak mengharapkan fungsi reproduksi lagi. Kata Kunci: nyeri perut, endometriosis, infertilitas, dismenore.","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"148 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76760127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-01DOI: 10.24815/jks.v19i2.18058
Denaneer Rahmadatu, Erma Sulistyaningsih, Dini Agustina
Abstrak. Asma merupakan gangguan inflamasi kronik saluran napas yang bersifat hiperesponsif yang ditandai adanya gejala episodik berulang berupa mengi, sesak napas, dada terasa berat, dan batuk, terutama pada malam hari atau dini hari. Sekitar 50-80% asma disebabkan oleh tungau debu rumah (TDR), khususnya Dermatophagoides pteronyssinus dan Dermatophagoides farinae. Penelitian ini bertujuan untuk mengetahui apakah terdapat hubungan antara kepadatan Dermatophagoides spp. pada debu rumah dengan frekuensi serangan asma pada penderita asma di RS Paru Jember. Penelitian ini merupakan penelitian analitik observasional dengan desain penelitian cross-sectional. Sampel penelitian ini yaitu 30 penderita asma di RS Paru Jember yang diambil menggunakan teknik simple random sampling sesuai dengan kriteria inklusi dan eksklusi. Peneliti melakukan interview mengenai frekuensi serangan asma dalam tiga bulan terakhir, mengambil debu dari ruang tamu dan ruang tidur pada rumah penderita asma, dan mengidentifikasi tungau debu rumah (TDR) yang ditemukan pada debu. Hasil uji Pearson mendapatkan nilai p=0,011 dan nilai r=0,475 sehingga dapat disimpulkan bahwa terdapat hubungan bermakna antara kepadatan Dermatophagoides spp. dengan frekuensi serangan asma dengan kekuatan korelasi sedang pada penderita asma di RS Paru Jember. Kata Kunci: Dermatophagoides spp., Tungau Debu Rumah (TDR), Asma Abstract. Asthma is a chronic inflammatory disorder of the respiratory system characterized by recurrent episodes of wheezing, shortness of breath, chest tightness, and cough, particularly at night or early morning. About 50-80% of asthma is caused by house dust mite (HDM), especially Dermatophagoides pteronyssinus and Dermatophagoides farinae. This study aimed to investigate the correlation between the density of Dermatophagoides spp. and the frequency of asthma attacks in asthmatic patients at Jember Pulmonary Hospital. This study was an observational analytic study with a cross-sectional design. Respondents were 30 asthmatic patients at Jember Pulmonary Hospital matched with inclusion and exclusion criteria and chose by simple random sampling. Respondents were interviewed about the frequency of asthma attacks in the last three month,s and the hose dust from the living and sleeping rooms were collected for identification of house dust mites (HDM). The pearson test showed a value of p=0.011 and r=0.475. It can be concluded that there is a significant correlation with the moderate strenght between the density of Dermatophagoides spp. and the frequency of asthma attacks in the asthmatic patient at Jember Pulmonary Hospital. Keywords: Dermatophagoides spp., House Dust Mites (HDM), Asthma
{"title":"HUBUNGAN KEPADATAN DERMATOPHAGOIDES SPP. DENGAN FREKUENSI SERANGAN ASMA PADA PENDERITA ASMA DI RS PARU JEMBER","authors":"Denaneer Rahmadatu, Erma Sulistyaningsih, Dini Agustina","doi":"10.24815/jks.v19i2.18058","DOIUrl":"https://doi.org/10.24815/jks.v19i2.18058","url":null,"abstract":"Abstrak. Asma merupakan gangguan inflamasi kronik saluran napas yang bersifat hiperesponsif yang ditandai adanya gejala episodik berulang berupa mengi, sesak napas, dada terasa berat, dan batuk, terutama pada malam hari atau dini hari. Sekitar 50-80% asma disebabkan oleh tungau debu rumah (TDR), khususnya Dermatophagoides pteronyssinus dan Dermatophagoides farinae. Penelitian ini bertujuan untuk mengetahui apakah terdapat hubungan antara kepadatan Dermatophagoides spp. pada debu rumah dengan frekuensi serangan asma pada penderita asma di RS Paru Jember. Penelitian ini merupakan penelitian analitik observasional dengan desain penelitian cross-sectional. Sampel penelitian ini yaitu 30 penderita asma di RS Paru Jember yang diambil menggunakan teknik simple random sampling sesuai dengan kriteria inklusi dan eksklusi. Peneliti melakukan interview mengenai frekuensi serangan asma dalam tiga bulan terakhir, mengambil debu dari ruang tamu dan ruang tidur pada rumah penderita asma, dan mengidentifikasi tungau debu rumah (TDR) yang ditemukan pada debu. Hasil uji Pearson mendapatkan nilai p=0,011 dan nilai r=0,475 sehingga dapat disimpulkan bahwa terdapat hubungan bermakna antara kepadatan Dermatophagoides spp. dengan frekuensi serangan asma dengan kekuatan korelasi sedang pada penderita asma di RS Paru Jember. Kata Kunci: Dermatophagoides spp., Tungau Debu Rumah (TDR), Asma Abstract. Asthma is a chronic inflammatory disorder of the respiratory system characterized by recurrent episodes of wheezing, shortness of breath, chest tightness, and cough, particularly at night or early morning. About 50-80% of asthma is caused by house dust mite (HDM), especially Dermatophagoides pteronyssinus and Dermatophagoides farinae. This study aimed to investigate the correlation between the density of Dermatophagoides spp. and the frequency of asthma attacks in asthmatic patients at Jember Pulmonary Hospital. This study was an observational analytic study with a cross-sectional design. Respondents were 30 asthmatic patients at Jember Pulmonary Hospital matched with inclusion and exclusion criteria and chose by simple random sampling. Respondents were interviewed about the frequency of asthma attacks in the last three month,s and the hose dust from the living and sleeping rooms were collected for identification of house dust mites (HDM). The pearson test showed a value of p=0.011 and r=0.475. It can be concluded that there is a significant correlation with the moderate strenght between the density of Dermatophagoides spp. and the frequency of asthma attacks in the asthmatic patient at Jember Pulmonary Hospital. Keywords: Dermatophagoides spp., House Dust Mites (HDM), Asthma","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83657848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-01DOI: 10.24815/jks.v19i2.18064
Dino Irawan, Nopian Hidayat
Abstrak. Penelitian ini berjudul perbandingan tingkat kenyamanan pasca pembiusan umum dengan endotracheal tube antara pemberian dexametasone intravena dan lidocaine spray di RSUD Arifin Achmad Provinsi Riau. Tingkat kenyamanan berupa nyeri tenggorok pada pasien yang menjalani pembiusan umum dengan intubasi endotrakeal dapat dipengaruhi oleh beberapa hal yaitu obat-obatan yang diberikan, teknik insersi, tekanan cuff dan manajemen setelah insersi.Nyeri tenggorok pada pasien yang menjalani anestesi umum dengan intubasi endotrakeal pada umumnya tidak berakibat fatal dan akan menghilang dalam 48-72 jam setelah operasi tetapi hal ini dapat menyebabkan gangguan yang cukup berarti bagi pasien, menambah lama dan biaya rawatan pasien di rumah sakit serta meninggalkan kesan buruk terhadap operasi. Penelitian ini menggunakan pendekatan randomized clinical controlled trial dengan rancangan eksperimental yang dilakukan pada 104 pasien yang menjalani anestesi umum dengan endotrakeal tube di RSUD Arifin Achmad Provinsi Riau pada bulan September-Oktober 2019. Pada hasil penelitian didapatkan bahwa pemberian dexametasone intravena sebelum tindakan intubasi endotrakeal lebih efektif dalam mencegah nyeri tenggorok pasca operasi dibandingkan lidocaine spray (19.2% untuk Dexametasone intravena dan 29.8% pada Lidocaine spray). Secara statistik, perbedaan kejadian nyeri tenggorok antara kelompok Dexametasone intravena dan Lidocaine spray adalah bermakna pada skoring 1 jam post operasi (p 0.05) dan tidak bermakna pada skoring 24 jam post operasi (p0.05). Insidensi nyeri tenggorok terbanyak berdasarkan usia adalah pada kelompok usia 46-55 tahun dan 55-65 tahun, berdasarkan jenis kelamin adalah lebih banyak pada perempuan dibandingkan laki-laki, dan lebih banyak pada pasien yang mempunyai riwayat merokok. Kata kunci: nyeri tenggorok, dexametasone intravena, lidocaine spray, RSUD Arifin Achmad Provinsi Riau Abstract. This study is about the comparison of the level of comfort after general anesthesia with an endotracheal tube between administration of intravenous dexametasone and lidocaine spray in Arifin Achmad General Hospital of Riau Province. The level of comfort in the form of sore throat in patients undergoing general anesthesia with endotracheal intubation can be influenced by several things such as administration of drugs, insertion techniques, cuff pressure and management after insertion. Sore throat in patients undergoing general anesthesia with endotracheal intubation is generally not fatal and will disappear within 48-72 hours after surgery but this can cause significant disruption to the patient, increase the length and cost of patient care in the hospital and leave bad impression from surgery. This study is a randomized clinical controlled trial with an experimental design conducted on 104 patients undergoing general anesthesia with endotracheal tube at Arifin Achmad General Hospital in Riau Province in September-October 2019. The study found that administrati
{"title":"PERBANDINGAN PEMBERIAN DEXAMETHASONE 10 MG INTRAVENA DAN LIDOCAINE SPRAY PADA TINGKAT KENYAMANAN PASCA INTUBASI ENDOTRACHEAL TUBE DI RSUD ARIFIN ACHMAD PROVINSI RIAU","authors":"Dino Irawan, Nopian Hidayat","doi":"10.24815/jks.v19i2.18064","DOIUrl":"https://doi.org/10.24815/jks.v19i2.18064","url":null,"abstract":"Abstrak. Penelitian ini berjudul perbandingan tingkat kenyamanan pasca pembiusan umum dengan endotracheal tube antara pemberian dexametasone intravena dan lidocaine spray di RSUD Arifin Achmad Provinsi Riau. Tingkat kenyamanan berupa nyeri tenggorok pada pasien yang menjalani pembiusan umum dengan intubasi endotrakeal dapat dipengaruhi oleh beberapa hal yaitu obat-obatan yang diberikan, teknik insersi, tekanan cuff dan manajemen setelah insersi.Nyeri tenggorok pada pasien yang menjalani anestesi umum dengan intubasi endotrakeal pada umumnya tidak berakibat fatal dan akan menghilang dalam 48-72 jam setelah operasi tetapi hal ini dapat menyebabkan gangguan yang cukup berarti bagi pasien, menambah lama dan biaya rawatan pasien di rumah sakit serta meninggalkan kesan buruk terhadap operasi. Penelitian ini menggunakan pendekatan randomized clinical controlled trial dengan rancangan eksperimental yang dilakukan pada 104 pasien yang menjalani anestesi umum dengan endotrakeal tube di RSUD Arifin Achmad Provinsi Riau pada bulan September-Oktober 2019. Pada hasil penelitian didapatkan bahwa pemberian dexametasone intravena sebelum tindakan intubasi endotrakeal lebih efektif dalam mencegah nyeri tenggorok pasca operasi dibandingkan lidocaine spray (19.2% untuk Dexametasone intravena dan 29.8% pada Lidocaine spray). Secara statistik, perbedaan kejadian nyeri tenggorok antara kelompok Dexametasone intravena dan Lidocaine spray adalah bermakna pada skoring 1 jam post operasi (p 0.05) dan tidak bermakna pada skoring 24 jam post operasi (p0.05). Insidensi nyeri tenggorok terbanyak berdasarkan usia adalah pada kelompok usia 46-55 tahun dan 55-65 tahun, berdasarkan jenis kelamin adalah lebih banyak pada perempuan dibandingkan laki-laki, dan lebih banyak pada pasien yang mempunyai riwayat merokok. Kata kunci: nyeri tenggorok, dexametasone intravena, lidocaine spray, RSUD Arifin Achmad Provinsi Riau Abstract. This study is about the comparison of the level of comfort after general anesthesia with an endotracheal tube between administration of intravenous dexametasone and lidocaine spray in Arifin Achmad General Hospital of Riau Province. The level of comfort in the form of sore throat in patients undergoing general anesthesia with endotracheal intubation can be influenced by several things such as administration of drugs, insertion techniques, cuff pressure and management after insertion. Sore throat in patients undergoing general anesthesia with endotracheal intubation is generally not fatal and will disappear within 48-72 hours after surgery but this can cause significant disruption to the patient, increase the length and cost of patient care in the hospital and leave bad impression from surgery. This study is a randomized clinical controlled trial with an experimental design conducted on 104 patients undergoing general anesthesia with endotracheal tube at Arifin Achmad General Hospital in Riau Province in September-October 2019. The study found that administrati","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"28 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83957227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-01DOI: 10.24815/jks.v19i2.18065
Muhammad Ridho Rizky Nanda, Rizki Rahmadhani, Mohd. Andalas Mohd. Andalas
Abstrak. Hiperemesis gravidarum adalah muntah yang terjadi pada awal kehamilan sampai akhir kehamilan 20 minggu. Etiologinya belum diketahui secara pasti, tetapi beberapa ahli yang menyatakan bahwa erat hubungannya dengan faktor endokrin dan non endokrin. Mual dan muntah terjadi pada 60-80 % primigravida dan 40-60 % multigravida. 3, 4 Presentase hormon β-HCG akan meningkat sesuai dengan pertumbuhan plasenta. Diperkirakan hormon inilah yang mengakibatkan muntah melalui rangsangan terhadap otot polos lambung. Sehingga, semakin tinggi hormon HCG, semakin cepat pula rangsangan terhadap muntah mengakibatkan terhambatnya pertumbuhan janin. 4, 5, 6 Pada laporan kasus ini, kami memaparkan seorang wanita G1 Hamil 14-15 minggu datang dengan keluhan lemas akibat mual dan muntah sebanyak 20 kali sehari sejak 1 hari sebelum masuk rumah sakit. Berdasarkan pemeriksaan fisik ditemukan mata cekung dengan turgor kembali 2 detik. Hasil Laboratorium menunjukkan adanya hipoglikemia, dan ketonuria. Hasil ultrasonography (USG) ditemukan janin tunggal hidup intrauterin, usia kehamilan 11-12 minggu, CRL 4,63 cm. Berdasarkan PUQE (Pregnancy Unique Quantification of Emesis and Nausea) score, pasien didiagnosis dengan hiperemesis gravidarum stadium 1 dan mendapatkan terapi cairan, injeksi anti-emetik 4 mg/2 ml per 8 jam, asam folat 400 mcg per hari, dan suplementasi vitamin B kompleks per hari.Kata Kunci : Hiperemesis gravidarum, ketonuria, PUQE score
{"title":"HIPEREMESIS GRAVIDARUM","authors":"Muhammad Ridho Rizky Nanda, Rizki Rahmadhani, Mohd. Andalas Mohd. Andalas","doi":"10.24815/jks.v19i2.18065","DOIUrl":"https://doi.org/10.24815/jks.v19i2.18065","url":null,"abstract":"Abstrak. Hiperemesis gravidarum adalah muntah yang terjadi pada awal kehamilan sampai akhir kehamilan 20 minggu. Etiologinya belum diketahui secara pasti, tetapi beberapa ahli yang menyatakan bahwa erat hubungannya dengan faktor endokrin dan non endokrin. Mual dan muntah terjadi pada 60-80 % primigravida dan 40-60 % multigravida. 3, 4 Presentase hormon β-HCG akan meningkat sesuai dengan pertumbuhan plasenta. Diperkirakan hormon inilah yang mengakibatkan muntah melalui rangsangan terhadap otot polos lambung. Sehingga, semakin tinggi hormon HCG, semakin cepat pula rangsangan terhadap muntah mengakibatkan terhambatnya pertumbuhan janin. 4, 5, 6 Pada laporan kasus ini, kami memaparkan seorang wanita G1 Hamil 14-15 minggu datang dengan keluhan lemas akibat mual dan muntah sebanyak 20 kali sehari sejak 1 hari sebelum masuk rumah sakit. Berdasarkan pemeriksaan fisik ditemukan mata cekung dengan turgor kembali 2 detik. Hasil Laboratorium menunjukkan adanya hipoglikemia, dan ketonuria. Hasil ultrasonography (USG) ditemukan janin tunggal hidup intrauterin, usia kehamilan 11-12 minggu, CRL 4,63 cm. Berdasarkan PUQE (Pregnancy Unique Quantification of Emesis and Nausea) score, pasien didiagnosis dengan hiperemesis gravidarum stadium 1 dan mendapatkan terapi cairan, injeksi anti-emetik 4 mg/2 ml per 8 jam, asam folat 400 mcg per hari, dan suplementasi vitamin B kompleks per hari.Kata Kunci : Hiperemesis gravidarum, ketonuria, PUQE score","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78147102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-01DOI: 10.24815/jks.v19i2.18060
Sarah Izdihar, M. Yusuf, Meisy Andriana
Abstrak. Latar Belakang: Difteri adalah penyakit menular mematikan yang dapat menjadi peristiwa luar biasa yang disebabkan oleh Corynebacterium diphtheria. Kasus difteri di Indonesia meningkat dan yang terbesar di Jawa Timur terutama di Surabaya pada tahun 2017 tergolong tinggi karena rendahnya cakupan imunisasi difteri. Difteri rongga mulut (tonsil-faring-laring) adalah yang paling sering (90%). Populasi risiko tinggi biasanya anak-anak yang tidak diimunisasi atau daerah dengan cakupan imunisasi DPT3 dan DT yang rendah. Tujuan: Menganalisis faktor-faktor yang mempengaruhi difteri di Surabaya. Metode dan Materi: Jenis penelitian ini adalah penelitian deskriptif retrospektif dengan menggunakan total sampling. Sampel penelitian berjumlah 82. Data dikumpulkan melalui buku catatan Ruang Isolasi Khusus RSUD Dr. Soetomo Surabaya dan rekam medis elektronik. Hasil: Dari 82 sampel, distribusi responden menunjukkan bahwa kelompok jenis kelamin tertinggi adalah pria (64,63%), Usia didominasi oleh 0-5 tahun (46,34%) dan 6-11 tahun (34,14%), Pendidikan terakhir terbanyak adalah SD (24,39%), dan kota terbanyak adalah Surabaya (56,09%). Status imunisasi DPT terbanyak adalah tidak lengkap (63,41%), lokasi difteri terbanyak di tonsil (92,68%), terapi terbanyak yaitu penisilin procain 92,68%. Simpulan: difteri terbanyak didapatkan pada usia 0-11 tahun, berjenis kelamin laki-laki, mayoritas bertempat tinggal Surabaya, tingkat pendidikan terbanyak SD, status imunisasi DPT terbanyak adalah tidak lengkap, lokasi difteri terbanyak tonsil, jenis terapi terbanyak penisilin procain. Kata Kunci: Difteri, Tonsil, Imunisasi Abstract. Background: Diphtheria is a deadly infectious disease that can be an extraordinary event caused by Corynebacterium diphtheria. Diphtheria cases in Indonesia increased and the largest in East Java, especially in Surabaya in 2017 was classified as high due to the low coverage of diphtheria immunization. Diphtheria of the oral cavity (tonsils-pharynx-larynx) is the most frequent ( 90%). High risk populations are usually children who are not immunized or areas with low DPT3 and DT immunization coverage. Objective: The purpose of this study was to analyze the factors that influence diphtheria in Surabaya. Material and Methods: The type of research is a retrospective descriptive study using total sampling. The research sample was 82. The data was collected through the Special Isolation Room Dr. RS. Soetomo Surabaya and electronic medical records. Results: From 82 samples, showed that the highest gender group was male (64.63%), age was dominated by 0-5 years (46.34%) and 6-11 years (34.14%), the most recent education was SD (24.39%), and most cities are Surabaya (56.09%). Most DPT immunization status is incomplete (63.41%), most diphtheria locations in tonsils (92.68%), the most therapy is penicillin procain 92.68%. Conclusio: Diphtheria is found at the age of 0-11 years, male sex, the majority lives in Surabaya, the highest level of education is el
{"title":"PROFIL PENDERITA DIFTERI YANG DIRAWAT YANG DIRAWAT DI RUANG ISOLASI KHUSUS RSUD Dr. SOETOMO SURABAYA","authors":"Sarah Izdihar, M. Yusuf, Meisy Andriana","doi":"10.24815/jks.v19i2.18060","DOIUrl":"https://doi.org/10.24815/jks.v19i2.18060","url":null,"abstract":"Abstrak. Latar Belakang: Difteri adalah penyakit menular mematikan yang dapat menjadi peristiwa luar biasa yang disebabkan oleh Corynebacterium diphtheria. Kasus difteri di Indonesia meningkat dan yang terbesar di Jawa Timur terutama di Surabaya pada tahun 2017 tergolong tinggi karena rendahnya cakupan imunisasi difteri. Difteri rongga mulut (tonsil-faring-laring) adalah yang paling sering (90%). Populasi risiko tinggi biasanya anak-anak yang tidak diimunisasi atau daerah dengan cakupan imunisasi DPT3 dan DT yang rendah. Tujuan: Menganalisis faktor-faktor yang mempengaruhi difteri di Surabaya. Metode dan Materi: Jenis penelitian ini adalah penelitian deskriptif retrospektif dengan menggunakan total sampling. Sampel penelitian berjumlah 82. Data dikumpulkan melalui buku catatan Ruang Isolasi Khusus RSUD Dr. Soetomo Surabaya dan rekam medis elektronik. Hasil: Dari 82 sampel, distribusi responden menunjukkan bahwa kelompok jenis kelamin tertinggi adalah pria (64,63%), Usia didominasi oleh 0-5 tahun (46,34%) dan 6-11 tahun (34,14%), Pendidikan terakhir terbanyak adalah SD (24,39%), dan kota terbanyak adalah Surabaya (56,09%). Status imunisasi DPT terbanyak adalah tidak lengkap (63,41%), lokasi difteri terbanyak di tonsil (92,68%), terapi terbanyak yaitu penisilin procain 92,68%. Simpulan: difteri terbanyak didapatkan pada usia 0-11 tahun, berjenis kelamin laki-laki, mayoritas bertempat tinggal Surabaya, tingkat pendidikan terbanyak SD, status imunisasi DPT terbanyak adalah tidak lengkap, lokasi difteri terbanyak tonsil, jenis terapi terbanyak penisilin procain. Kata Kunci: Difteri, Tonsil, Imunisasi Abstract. Background: Diphtheria is a deadly infectious disease that can be an extraordinary event caused by Corynebacterium diphtheria. Diphtheria cases in Indonesia increased and the largest in East Java, especially in Surabaya in 2017 was classified as high due to the low coverage of diphtheria immunization. Diphtheria of the oral cavity (tonsils-pharynx-larynx) is the most frequent ( 90%). High risk populations are usually children who are not immunized or areas with low DPT3 and DT immunization coverage. Objective: The purpose of this study was to analyze the factors that influence diphtheria in Surabaya. Material and Methods: The type of research is a retrospective descriptive study using total sampling. The research sample was 82. The data was collected through the Special Isolation Room Dr. RS. Soetomo Surabaya and electronic medical records. Results: From 82 samples, showed that the highest gender group was male (64.63%), age was dominated by 0-5 years (46.34%) and 6-11 years (34.14%), the most recent education was SD (24.39%), and most cities are Surabaya (56.09%). Most DPT immunization status is incomplete (63.41%), most diphtheria locations in tonsils (92.68%), the most therapy is penicillin procain 92.68%. Conclusio: Diphtheria is found at the age of 0-11 years, male sex, the majority lives in Surabaya, the highest level of education is el","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78516853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstrak. Latar Belakang: Penyakit Ulkus Genital meningkatkan risiko tertularnya HIV. Di Indonesia, belum ada data pasti prevalensi pasien Ulkus Genital, juga di RSUD Dr. Soetomo Surabaya. Tujuan: Mengevaluasi profil pasien Ulkus Genital di Unit Rawat Kulit dan Kelamin RSUD Dr. Soetomo Surabaya.Metode: Penelitian ini merupakan jenis penelitian deskriptif retrospektif dengan data sekunder. Populasi penelitian adalah semua rekam medik pasien dengan Ulkus Genital yang dirawat di Unit Rawat Jalan Kulit dan Kelamin RSUD Dr. Soetomo Surabaya tahun 2016, 2017, dan 2018. Sampel diambil menggunakan purposive sampling tanpa eksklusi. Hasil : Ditemukan 36 sampel pasien dengan Ulkus Genital selama tiga tahun dengan distribusi usia antara 13 sampai 64 tahun. Usia yang paling mendominasi adalah kelompok usia 20 – 24 tahun sebanyak 30,56%. Sebagian besar sampel berjenis kelamin perempuan, sudah kawin, dan hanya berhubungan dengan lawan jenis. Diagnosis utama pasien Ulkus Genital paling banyak adalah Herpesviral infection of genitalia and urogenital tract. Tipe Ulkus Genital terbanyak adalah Ulkus Herpes dan pemeriksaan penunjang terbanyak yang dilakukan adalah Pemeriksaan Gram. Outcome/Hasil Terapi kebanyakan menunjukkan perkembangan yang baik kearah kesembuhan. Sebagian besar pasien Ulkus Genital datang tanpa kelainan penyerta. Kesimpulan: Mayoritas pasien sebanyak 53,8% dengan Ulkus Genital mengidap Herpes Simplek Primer. Kata Kunci: Ulkus Genital, Herpes Simplek PrimerAbstract. Background: Genital ulcer disease increases the risk of contracting HIV. In Indonesia, there is no exact data on the prevalence of Genital Ulcer patients, also in Dr. Soetomo Surabaya.Purpose: Evaluating the profile of genital ulcer patients in outpatient care unit Department of Dermatology and Venereology Dr. Soetomo General Academic Hospital.Methods: This is a retrospective descriptive reseach with secondary data. The study population was all medical records of patients with genital ulcers who were treated in the Department of Dermatology and Venereology Dr. Soetomo General Academic Hospital in 2016, 2017 and 2018. Samples were taken using purposive sampling without exclusion.Results: There were 36 samples of patients with genital ulcers for three years with age distribution between 13 to 64 years. The most dominant age group is in the age group of 20-24 years by 30.56%. Most of the samples were female, married, and only related to the opposite sex. The main diagnosis of most genital ulcer patients is Herpesviral infection of genitalia and urogenital tract. The most common type of genital ulcer is herpes ulcer and the most investigation is carried out is Gram examination. Outcome results mostly show good progress toward healing. Most patients with genital ulcer come without comorbidities.Conclusion: The majority of patients were 53.8% with genital ulcer suffering from Herpesviral infection of genitalia and urogenital tract.Keywords: Genital Ulcer, Herpesviral infection
{"title":"PROFIL PASIEN ULKUS GENITAL DI UNIT RAWAT JALAN KULIT DAN KELAMIN RSUD DR. SOETOMO SURABAYA","authors":"Senda Sulvain Rahmaningrat, Afifah Hidayati, Erwin Astha Triyono, Dwi Aprilawati","doi":"10.24815/jks.v19i2.18059","DOIUrl":"https://doi.org/10.24815/jks.v19i2.18059","url":null,"abstract":"Abstrak. Latar Belakang: Penyakit Ulkus Genital meningkatkan risiko tertularnya HIV. Di Indonesia, belum ada data pasti prevalensi pasien Ulkus Genital, juga di RSUD Dr. Soetomo Surabaya. Tujuan: Mengevaluasi profil pasien Ulkus Genital di Unit Rawat Kulit dan Kelamin RSUD Dr. Soetomo Surabaya.Metode: Penelitian ini merupakan jenis penelitian deskriptif retrospektif dengan data sekunder. Populasi penelitian adalah semua rekam medik pasien dengan Ulkus Genital yang dirawat di Unit Rawat Jalan Kulit dan Kelamin RSUD Dr. Soetomo Surabaya tahun 2016, 2017, dan 2018. Sampel diambil menggunakan purposive sampling tanpa eksklusi. Hasil : Ditemukan 36 sampel pasien dengan Ulkus Genital selama tiga tahun dengan distribusi usia antara 13 sampai 64 tahun. Usia yang paling mendominasi adalah kelompok usia 20 – 24 tahun sebanyak 30,56%. Sebagian besar sampel berjenis kelamin perempuan, sudah kawin, dan hanya berhubungan dengan lawan jenis. Diagnosis utama pasien Ulkus Genital paling banyak adalah Herpesviral infection of genitalia and urogenital tract. Tipe Ulkus Genital terbanyak adalah Ulkus Herpes dan pemeriksaan penunjang terbanyak yang dilakukan adalah Pemeriksaan Gram. Outcome/Hasil Terapi kebanyakan menunjukkan perkembangan yang baik kearah kesembuhan. Sebagian besar pasien Ulkus Genital datang tanpa kelainan penyerta. Kesimpulan: Mayoritas pasien sebanyak 53,8% dengan Ulkus Genital mengidap Herpes Simplek Primer. Kata Kunci: Ulkus Genital, Herpes Simplek PrimerAbstract. Background: Genital ulcer disease increases the risk of contracting HIV. In Indonesia, there is no exact data on the prevalence of Genital Ulcer patients, also in Dr. Soetomo Surabaya.Purpose: Evaluating the profile of genital ulcer patients in outpatient care unit Department of Dermatology and Venereology Dr. Soetomo General Academic Hospital.Methods: This is a retrospective descriptive reseach with secondary data. The study population was all medical records of patients with genital ulcers who were treated in the Department of Dermatology and Venereology Dr. Soetomo General Academic Hospital in 2016, 2017 and 2018. Samples were taken using purposive sampling without exclusion.Results: There were 36 samples of patients with genital ulcers for three years with age distribution between 13 to 64 years. The most dominant age group is in the age group of 20-24 years by 30.56%. Most of the samples were female, married, and only related to the opposite sex. The main diagnosis of most genital ulcer patients is Herpesviral infection of genitalia and urogenital tract. The most common type of genital ulcer is herpes ulcer and the most investigation is carried out is Gram examination. Outcome results mostly show good progress toward healing. Most patients with genital ulcer come without comorbidities.Conclusion: The majority of patients were 53.8% with genital ulcer suffering from Herpesviral infection of genitalia and urogenital tract.Keywords: Genital Ulcer, Herpesviral infection","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86474632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-01DOI: 10.24815/jks.v19i2.18062
Dedi Afandi, K. Khodijah, Fajri Marindra Siregar, Maysarah Elnas
Abstrak. Penentuan tinggi badan memiliki peran penting dalam menentukan identitas personal pada kasus penemuan jenazah yang tubuhnya sudah tidak utuh lagi. Perkiraan tinggi badan pada jenazah yang tidak utuh dapat diketahui dengan mengukur panjang bagian tubuh tertentu dari jenazah tersebut, salah satunya adalah panjang tulang sternum. Tujuan penelitian ini adalah untuk mengetahui korelasi dan menentukan rumus perkiraan tinggi badan berdasarkan jenis kelamin menggunakan panjang tulang sternum. Penelitian ini merupakan penelitian analitik dengan pendekatan cross sectional. Untuk mengetahui korelasi dan menentukan rumus regresi linier dilakukan uji statistik dengan menggunakan software IBM SPSS 26.0. Pada penelitian ini dilakukan pengukuran tinggi badan dan panjang tulang sternum pada 230 responden (115 pria dan 115 wanita) yang berusia 18-45 tahun di Provinsi Riau. Didapatkan korelasi bermakna antara panjang tulang sternum dengan tinggi badan (p0,01) pada responden pria dan wanita. Nilai koefisien korelasi pada responden pria (r = 0,33) dan wanita (r = 0,24) menunjukkan kekuatan korelasi lemah. Rumus regresi tinggi badan pada pria didapatkan yaitu: TB = 144,35 + 1,13(PS) ± 6,44 cm dan pada wanita: TB = 139,20 + 0,96(PS) ± 4,87 cm. Hasil penelitian ini menunjukkan bahwa panjang tulang sternum memiliki nilai forensik terbatas dan keandalan yang relatif rendah dalam memperkirakan tinggi badan manusia.Kata Kunci: Identifikasi, sternum, tinggi badan, korelasi, formula regresiAbstract. The determination of body height possesses a great and important role in establishing personal identities when founding an incomplete human corpse. The estimation of body height can be determined by measuring certain parts of the body, one of which is the length of the sternal bone. The purpose of this study was to understand the correlation and determining the approximate height equation based on sex using the sternal length. An analytical study with a cross-sectional approach was used in this research. To perceiving the correlation and determining the linear regression formula, a statistical test was performed using IBM SPSS 26.0. In this study, height measurement and the sternal length were recorded from 230 respondents (115 males and 115 females), aged between 18-45 years old in Riau Province. A significant correlation was obtained between sternal length and body height (p 0,01) in male and female respondents. The correlation coefficient (r) score for male (r = 0,33) and female (r = 0,24) respondents indicates a weak correlation strength. Height regression formula in men is obtained, namely: Body Height = 144,35 + 1,13(Sternal Length) ± 6,44 cm and in women: Body Height = 139,20 + 0,96(Sternal length) ± 4,87 cm. The result of this study shows that the length of the sternum bone has limited forensic value and relatively low reliability in estimating human height.Keywords: Identification, sternum, height, correlation, regression formula
{"title":"KORELASI ANTARA PANJANG TULANG STERNUM DENGAN TINGGI BADAN BERDASARKAN JENIS KELAMIN PADA RAS MONGOLOID USIA 18-45 TAHUN DI PROVINSI RIAU","authors":"Dedi Afandi, K. Khodijah, Fajri Marindra Siregar, Maysarah Elnas","doi":"10.24815/jks.v19i2.18062","DOIUrl":"https://doi.org/10.24815/jks.v19i2.18062","url":null,"abstract":"Abstrak. Penentuan tinggi badan memiliki peran penting dalam menentukan identitas personal pada kasus penemuan jenazah yang tubuhnya sudah tidak utuh lagi. Perkiraan tinggi badan pada jenazah yang tidak utuh dapat diketahui dengan mengukur panjang bagian tubuh tertentu dari jenazah tersebut, salah satunya adalah panjang tulang sternum. Tujuan penelitian ini adalah untuk mengetahui korelasi dan menentukan rumus perkiraan tinggi badan berdasarkan jenis kelamin menggunakan panjang tulang sternum. Penelitian ini merupakan penelitian analitik dengan pendekatan cross sectional. Untuk mengetahui korelasi dan menentukan rumus regresi linier dilakukan uji statistik dengan menggunakan software IBM SPSS 26.0. Pada penelitian ini dilakukan pengukuran tinggi badan dan panjang tulang sternum pada 230 responden (115 pria dan 115 wanita) yang berusia 18-45 tahun di Provinsi Riau. Didapatkan korelasi bermakna antara panjang tulang sternum dengan tinggi badan (p0,01) pada responden pria dan wanita. Nilai koefisien korelasi pada responden pria (r = 0,33) dan wanita (r = 0,24) menunjukkan kekuatan korelasi lemah. Rumus regresi tinggi badan pada pria didapatkan yaitu: TB = 144,35 + 1,13(PS) ± 6,44 cm dan pada wanita: TB = 139,20 + 0,96(PS) ± 4,87 cm. Hasil penelitian ini menunjukkan bahwa panjang tulang sternum memiliki nilai forensik terbatas dan keandalan yang relatif rendah dalam memperkirakan tinggi badan manusia.Kata Kunci: Identifikasi, sternum, tinggi badan, korelasi, formula regresiAbstract. The determination of body height possesses a great and important role in establishing personal identities when founding an incomplete human corpse. The estimation of body height can be determined by measuring certain parts of the body, one of which is the length of the sternal bone. The purpose of this study was to understand the correlation and determining the approximate height equation based on sex using the sternal length. An analytical study with a cross-sectional approach was used in this research. To perceiving the correlation and determining the linear regression formula, a statistical test was performed using IBM SPSS 26.0. In this study, height measurement and the sternal length were recorded from 230 respondents (115 males and 115 females), aged between 18-45 years old in Riau Province. A significant correlation was obtained between sternal length and body height (p 0,01) in male and female respondents. The correlation coefficient (r) score for male (r = 0,33) and female (r = 0,24) respondents indicates a weak correlation strength. Height regression formula in men is obtained, namely: Body Height = 144,35 + 1,13(Sternal Length) ± 6,44 cm and in women: Body Height = 139,20 + 0,96(Sternal length) ± 4,87 cm. The result of this study shows that the length of the sternum bone has limited forensic value and relatively low reliability in estimating human height.Keywords: Identification, sternum, height, correlation, regression formula","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82643541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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